<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/vo.owl#"
     xml:base="http://purl.obolibrary.org/obo/vo.owl"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:obo="http://purl.obolibrary.org/obo/"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:xml="http://www.w3.org/XML/1998/namespace"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:obo1="http://data.bioontology.org/metadata/obo/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:swrl="http://www.w3.org/2003/11/swrl#"
     xmlns:chebi="http://purl.obolibrary.org/obo/chebi/"
     xmlns:swrlb="http://www.w3.org/2003/11/swrlb#"
     xmlns:terms="http://purl.org/dc/terms/"
     xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#"
     xmlns:metadata="http://data.bioontology.org/metadata/"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#">
    <owl:Ontology rdf:about="http://purl.obolibrary.org/obo/vo.owl">
        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/vo/releases/2025-05-24/vo.owl"/>
        <protege:defaultLanguage>en</protege:defaultLanguage>
        <dc:contributor>Chris mungall</dc:contributor>
        <dc:contributor>Erica Marcos</dc:contributor>
        <dc:contributor>Ningxian Fan</dc:contributor>
        <dc:contributor>Paul Fabry</dc:contributor>
        <dc:contributor>Randi Vita</dc:contributor>
        <dc:contributor>Ryan R. Brinkman</dc:contributor>
        <dc:contributor>Shunzhou Deng</dc:contributor>
        <dc:creator>Alan Ruttenburg</dc:creator>
        <dc:creator>Alexander D. Diehl</dc:creator>
        <dc:creator>Amogh Madireddi</dc:creator>
        <dc:creator>Anna Maria Masci</dc:creator>
        <dc:creator>Anthony Huffman</dc:creator>
        <dc:creator>Barry Smith</dc:creator>
        <dc:creator>Bjoern Peters</dc:creator>
        <dc:creator>Edison Ong</dc:creator>
        <dc:creator>Ellen Zhang</dc:creator>
        <dc:creator>Hong Yu</dc:creator>
        <dc:creator>Jason Hu</dc:creator>
        <dc:creator>Jie Zheng</dc:creator>
        <dc:creator>Kallan Roan</dc:creator>
        <dc:creator>Khadeejah Khan</dc:creator>
        <dc:creator>Lindsay Cowell</dc:creator>
        <dc:creator>Melanie Courtot</dc:creator>
        <dc:creator>Ningxian Fan</dc:creator>
        <dc:creator>Omar Tibi</dc:creator>
        <dc:creator>Philip Huang</dc:creator>
        <dc:creator>Randi Vita</dc:creator>
        <dc:creator>Rebecca Racz</dc:creator>
        <dc:creator>Richard H. Scheuermann</dc:creator>
        <dc:creator>Rohit Goru</dc:creator>
        <dc:creator>Ronak Sutariya</dc:creator>
        <dc:creator>Samantha G. Sayers (SGS)</dc:creator>
        <dc:creator>Taiyu Lin</dc:creator>
        <dc:creator>Thomas Todd</dc:creator>
        <dc:creator>Xingxian Li</dc:creator>
        <dc:creator>Yongqun &quot;Oliver&quot; He (YH)</dc:creator>
        <dc:creator>Yu Lin (YL)</dc:creator>
        <dc:creator>Yuanyi (Penny) Pan</dc:creator>
        <dc:creator>Yuping Zheng</dc:creator>
        <dc:creator>Zuoshuang &quot;Allen&quot; Xiang</dc:creator>
        <dc:description xml:lang="en">The Vaccine Ontology (VO) is a community-based biomedical ontology in the domain of vaccine and vaccination. VO aims to standardize vaccine types and annotations, integrate various vaccine data, and support computer-assisted reasoning. The VO supports basic vaccine R&amp;D and clinical vaccine usage. VO is being developed as a community-based ontology with support and collaborations from the vaccine and bio-ontology communities.</dc:description>
        <dc:format xml:lang="en">OWL-DL</dc:format>
        <dc:subject xml:lang="en">An ontology in the domain of vaccine and vaccination</dc:subject>
        <dc:title xml:lang="en">Vaccine Ontology</dc:title>
        <terms:license rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
        <owl:versionInfo>2025-05-24</owl:versionInfo>
    </owl:Ontology>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://data.bioontology.org/metadata/prefixIRI -->

    <owl:AnnotationProperty rdf:about="http://data.bioontology.org/metadata/prefixIRI"/>
    


    <!-- http://data.bioontology.org/metadata/treeView -->

    <owl:AnnotationProperty rdf:about="http://data.bioontology.org/metadata/treeView"/>
    


    <!-- http://data.bioontology.org/metadata/obo/part_of -->

    <owl:AnnotationProperty rdf:about="http://data.bioontology.org/metadata/obo/part_of"/>
    


    <!-- http://protege.stanford.edu/plugins/owl/protege#defaultLanguage -->

    <owl:AnnotationProperty rdf:about="http://protege.stanford.edu/plugins/owl/protege#defaultLanguage"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000179 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000179">
        <obo:IAO_0000115 xml:lang="en">Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification.</obo:IAO_0000115>
        <obo:IAO_0000232 xml:lang="en">Really of interest to developers only</obo:IAO_0000232>
        <rdfs:label xml:lang="en">BFO OWL specification label</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.w3.org/2000/01/rdf-schema#label"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000180 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000180">
        <obo:IAO_0000115 xml:lang="en">Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2</obo:IAO_0000115>
        <obo:IAO_0000119>Person:Alan Ruttenberg</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">Really of interest to developers only</obo:IAO_0000232>
        <rdfs:label xml:lang="en">BFO CLIF specification label</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.w3.org/2000/01/rdf-schema#label"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000111 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000111">
        <obo:IAO_0000111 xml:lang="en">editor preferred term</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">editor preferred term</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000112 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000112">
        <obo:IAO_0000111 xml:lang="en">example of usage</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">example of usage</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000113 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000113">
        <obo:IAO_0000111 xml:lang="en">in branch</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">GROUP:OBI</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI_0000277</obo:IAO_0000119>
        <rdfs:label xml:lang="en">in branch</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000114 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000114">
        <obo:IAO_0000111 xml:lang="en">has curation status</obo:IAO_0000111>
        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON:Bill Bug</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
        <rdfs:label xml:lang="en">has curation status</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000115 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115">
        <obo:IAO_0000111 xml:lang="en">definition</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2012-04-05: 
Barry Smith

The official OBI definition, explaining the meaning of a class or property: &apos;Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions&apos;  is terrible.

Can you fix to something like:

A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property.

Alan Ruttenberg

Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can&apos;t be evaluated by those criteria. 

On the specifics of the proposed definition:

We don&apos;t have definitions of &apos;meaning&apos; or &apos;expression&apos; or &apos;property&apos;. For &apos;reference&apos; in the intended sense I think we use the term &apos;denotation&apos;. For &apos;expression&apos;, I think we you mean symbol, or identifier. For &apos;meaning&apos; it differs for class and property. For class we want documentation that let&apos;s the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let&apos;s the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The &apos;intended reader&apos; part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. 

Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. 

We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2012-04-05: 
Barry Smith

The official OBI definition, explaining the meaning of a class or property: &apos;Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions&apos;  is terrible.

Can you fix to something like:

A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property.

Alan Ruttenberg

Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can&apos;t be evaluated by those criteria. 

On the specifics of the proposed definition:

We don&apos;t have definitions of &apos;meaning&apos; or &apos;expression&apos; or &apos;property&apos;. For &apos;reference&apos; in the intended sense I think we use the term &apos;denotation&apos;. For &apos;expression&apos;, I think we you mean symbol, or identifier. For &apos;meaning&apos; it differs for class and property. For class we want documentation that let&apos;s the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let&apos;s the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The &apos;intended reader&apos; part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. 

Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. 

We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.  </obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">definition</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000116 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000116">
        <obo:IAO_0000111 xml:lang="en">editor note</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obofoundry.org/obo/obi&gt;</obo:IAO_0000119>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">editor note</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000117 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117">
        <obo:IAO_0000111 xml:lang="en">term editor</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">term editor</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000118 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000118">
        <obo:IAO_0000111 xml:lang="en">alternative label</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like.</obo:IAO_0000115>
        <obo:IAO_0000117>OBO Operations committee</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
        <rdfs:comment>Consider re-defing to: An alternative name for a class or property which can mean the same thing as the preferred name (semantically equivalent, narrow, broad or related).</rdfs:comment>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">alternative label</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000119 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119">
        <obo:IAO_0000111 xml:lang="en">definition source</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON:Daniel Schober</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">definition source</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000231 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000231">
        <obo:IAO_0000111 xml:lang="en">has obsolescence reason</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
        <rdfs:label xml:lang="en">has obsolescence reason</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000232 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000232">
        <obo:IAO_0000111 xml:lang="en">curator note</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">An administrative note of use for a curator but of no use for a user</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">curator note</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000233 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233">
        <obo:IAO_0000111 xml:lang="en">term tracker item</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">An IRI or similar locator for a request or discussion of an ontology term.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000119>
        <rdfs:comment xml:lang="en">The &apos;tracker item&apos; can associate a tracker with a specific ontology term.</rdfs:comment>
        <rdfs:label xml:lang="en">term tracker item</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000234 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000234">
        <obo:IAO_0000111 xml:lang="en">ontology term requester</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg</obo:IAO_0000119>
        <rdfs:comment>The &apos;term requester&apos; can credit the person, organization or project who request the ontology term.</rdfs:comment>
        <rdfs:label xml:lang="en">ontology term requester</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000411 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000411">
        <obo:IAO_0000111 xml:lang="en">is denotator type</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Relates an class defined in an ontology, to the type of it&apos;s denotator</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">In OWL 2 add AnnotationPropertyRange(&apos;is denotator type&apos; &apos;denotator type&apos;)</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">is denotator type</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000412 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412">
        <obo:IAO_0000111 xml:lang="en">imported from</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">For external terms/classes, the ontology from which the term was imported</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">imported from</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000424 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000424">
        <obo:IAO_0000111 xml:lang="en">expand expression to</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">ObjectProperty: RO_0002104
Label: has plasma membrane part
Annotations: IAO_0000424 &quot;http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.org/obo/owl/GO#GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)&quot;
</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
        <rdfs:label xml:lang="en">expand expression to</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000425 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000425">
        <obo:IAO_0000111 xml:lang="en">expand assertion to</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">ObjectProperty: RO???
Label: spatially disjoint from
Annotations: expand_assertion_to &quot;DisjointClasses: (http://purl.obolibrary.org/obo/BFO_0000051 some ?X)  (http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)&quot;
</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
        <rdfs:label xml:lang="en">expand assertion to</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000426 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000426">
        <obo:IAO_0000111 xml:lang="en">first order logic expression</obo:IAO_0000111>
        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">first order logic expression</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000427 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000427">
        <obo:IAO_0000111 xml:lang="en">antisymmetric property</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">part_of antisymmetric property xsd:true</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">Use boolean value xsd:true to indicate that the property is an antisymmetric property</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">antisymmetric property</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/OMO_0001001"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000589 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000589">
        <obo:IAO_0000111 xml:lang="en">OBO foundry unique label</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">An alternative name for a class or property which is unique across the OBO Foundry.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = &apos;sequence &apos; + [label], etc. , MA could specify &apos;mouse + [label]&apos; etc. Upon importing terms, ontology developers can choose to use the &apos;OBO foundry unique label&apos; for an imported term or not. The same applies to tools .</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON:Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON:Chris Mungall</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON:Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBO Foundry &lt;http://obofoundry.org/&gt;</obo:IAO_0000119>
        <rdfs:label xml:lang="en">OBO foundry unique label</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000596 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000596">
        <obo:IAO_0000111 xml:lang="en">has ID digit count</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Ontology: &lt;http://purl.obolibrary.org/obo/ro/idrange/&gt;
  Annotations: 
     &apos;has ID prefix&apos;: &quot;http://purl.obolibrary.org/obo/RO_&quot;
     &apos;has ID digit count&apos; : 7,
     rdfs:label &quot;RO id policy&quot;
     &apos;has ID policy for&apos;: &quot;RO&quot;</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the &apos;has ID prefix&quot; annotation property value concatenated with an integer in the id range (left padded with &quot;0&quot;s to make this many digits)</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">has ID digit count</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000597 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000597">
        <obo:IAO_0000111 xml:lang="en">has ID range allocated</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Datatype: idrange:1
Annotations: &apos;has ID range allocated to&apos;: &quot;Chris Mungall&quot;
EquivalentTo: xsd:integer[&gt; 2151 , &lt;= 2300]
</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">has ID range allocated to</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000598 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000598">
        <obo:IAO_0000111 xml:lang="en">has ID policy for</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Ontology: &lt;http://purl.obolibrary.org/obo/ro/idrange/&gt;
  Annotations: 
     &apos;has ID prefix&apos;: &quot;http://purl.obolibrary.org/obo/RO_&quot;
     &apos;has ID digit count&apos; : 7,
     rdfs:label &quot;RO id policy&quot;
     &apos;has ID policy for&apos;: &quot;RO&quot;</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">Relating an ontology used to record id policy to the ontology namespace whose policy it manages</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">has ID policy for</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000599 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000599">
        <obo:IAO_0000111 xml:lang="en">has ID prefix</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Ontology: &lt;http://purl.obolibrary.org/obo/ro/idrange/&gt;
  Annotations: 
     &apos;has ID prefix&apos;: &quot;http://purl.obolibrary.org/obo/RO_&quot;
     &apos;has ID digit count&apos; : 7,
     rdfs:label &quot;RO id policy&quot;
     &apos;has ID policy for&apos;: &quot;RO&quot;</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with &quot;0&quot;s to make this many digits) to construct an ID for a term being created.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">has ID prefix</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000600 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000600">
        <obo:IAO_0000111 xml:lang="en">elucidation</obo:IAO_0000111>
        <obo:IAO_0000117 xml:lang="en">person:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Person:Barry Smith</obo:IAO_0000119>
        <obo:IAO_0000600 xml:lang="en">Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms</obo:IAO_0000600>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">elucidation</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000601 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000601">
        <obo:IAO_0000111 xml:lang="en">has associated axiom(nl)</obo:IAO_0000111>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
        <obo:IAO_0000600 xml:lang="en">An axiom associated with a term expressed using natural language</obo:IAO_0000600>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">has associated axiom(nl)</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000602 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000602">
        <obo:IAO_0000111 xml:lang="en">has associated axiom(fol)</obo:IAO_0000111>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
        <obo:IAO_0000600 xml:lang="en">An axiom expressed in first order logic using CLIF syntax</obo:IAO_0000600>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">has associated axiom(fol)</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000603 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000603">
        <obo:IAO_0000111 xml:lang="en">is allocated id range</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. &quot;IAO_0020000-IAO_0020999&quot;</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON:Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:comment xml:lang="en">Add as annotation triples in the granting ontology</rdfs:comment>
        <rdfs:label xml:lang="en">is allocated id range</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000700 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000700">
        <obo:IAO_0000111 xml:lang="en">has ontology root term</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Nicolas Matentzoglu</obo:IAO_0000117>
        <rdfs:label xml:lang="en">has ontology root term</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0006011 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0006011">
        <obo:IAO_0000111 xml:lang="en">may be identical to</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
        <obo:IAO_0000233 xml:lang="en">#40</obo:IAO_0000233>
        <obo:IAO_0000234 xml:lang="en">VFB</obo:IAO_0000234>
        <rdfs:comment xml:lang="en">Edges asserting this should be annotated with to record evidence supporting the assertion and its provenance.</rdfs:comment>
        <rdfs:label xml:lang="en">may be identical to</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0006012 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0006012">
        <obo:IAO_0000111 xml:lang="en">scheduled for obsoletion on or after</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Chris Mungall, Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000233 xml:lang="en">https://github.com/geneontology/go-ontology/issues/15532</obo:IAO_0000233>
        <obo:IAO_0000233 xml:lang="en">https://github.com/information-artifact-ontology/ontology-metadata/issues/32</obo:IAO_0000233>
        <obo:IAO_0000234 xml:lang="en">GO ontology</obo:IAO_0000234>
        <rdfs:label xml:lang="en">scheduled for obsoletion on or after</rdfs:label>
        <rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#dateTime"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0010000 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0010000">
        <obo:IAO_0000111 xml:lang="en">has axiom id</obo:IAO_0000111>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
        <obo:IAO_0000600 xml:lang="en">A URI that is intended to be unique label for an axiom used for tracking change to the ontology. For an axiom expressed in different languages, each expression is given the same URI</obo:IAO_0000600>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">has axiom label</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0100001 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0100001">
        <obo:IAO_0000111 xml:lang="en">term replaced by</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">Use on obsolete terms, relating the term to another term that can be used as a substitute</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000119>
        <rdfs:comment xml:lang="en">Add as annotation triples in the granting ontology</rdfs:comment>
        <rdfs:label xml:lang="en">term replaced by</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0001847 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001847">
        <obo:IAO_0000111 xml:lang="en">ISA alternative term</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">An alternative term used by the ISA tools project (http://isa-tools.org).</obo:IAO_0000115>
        <obo:IAO_0000116>Requested by Alejandra Gonzalez-Beltran
https://sourceforge.net/tracker/?func=detail&amp;aid=3603413&amp;group_id=177891&amp;atid=886178</obo:IAO_0000116>
        <obo:IAO_0000117>Person: Alejandra Gonzalez-Beltran</obo:IAO_0000117>
        <obo:IAO_0000117>Person: Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000119>ISA tools project (http://isa-tools.org)</obo:IAO_0000119>
        <rdfs:label xml:lang="en">ISA alternative term</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_9991118 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OBI_9991118">
        <obo:IAO_0000111>IEDB alternative term</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">An alternative term used by the IEDB.</obo:IAO_0000115>
        <obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000119>IEDB</obo:IAO_0000119>
        <rdfs:label>IEDB alternative term</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OGG_0000000006 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OGG_0000000006">
        <obo:IAO_0000115>A GeneID in the NCBI Gene database </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He, Yue Liu</obo:IAO_0000117>
        <rdfs:label xml:lang="en">NCBI GeneID</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OGG_0000000007 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OGG_0000000007">
        <obo:IAO_0000115>the NCBI LocusTag name of a gene </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He, Yue Liu</obo:IAO_0000117>
        <rdfs:label xml:lang="en">NCBI LocusTag</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OGG_0000000009 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OGG_0000000009">
        <obo:IAO_0000115>a date of content modification</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He, Yue Liu</obo:IAO_0000117>
        <rdfs:label xml:lang="en">modification date</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OGG_0000000015 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OGG_0000000015">
        <obo:IAO_0000115>The NCBITaxon ontology ID of an organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He, Yue Liu</obo:IAO_0000117>
        <rdfs:label xml:lang="en">organism NCBITaxon ID</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OGG_0000000017 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OGG_0000000017">
        <obo:IAO_0000115>A chromosome ID where a gene is located.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">chromosome ID of gene</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OGG_0000000018 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OGG_0000000018">
        <obo:IAO_0000115>an annotation property that specifies the type of a gene</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">type of gene</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OGG_0000000019 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OGG_0000000019">
        <obo:IAO_0000115>an annotation property that specifies a nomenclature status</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">nomenclature status</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OGG_0000000030 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OGG_0000000030">
        <obo:IAO_0000115>An annotation property that represents a gene&apos;s association with PubMed publication(s). </obo:IAO_0000115>
        <obo:IAO_0000117>Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">has PubMed association</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0001001 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0001001">
        <obo:IAO_0000115>This is an annotation used on an object property to indicate a logical characterstic beyond what is possible in OWL.</obo:IAO_0000115>
        <obo:IAO_0000119>OBO Operations call</obo:IAO_0000119>
        <oboInOwl:created_by rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
        <rdfs:label>logical characteristic of object property</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0002000 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0002000">
        <obo:IAO_0000112>&apos;part disjoint with&apos; &apos;defined by construct&apos; &quot;&quot;&quot;
    PREFIX owl: &lt;http://www.w3.org/2002/07/owl#&gt;
    PREFIX : &lt;http://example.org/
    CONSTRUCT {
      [
        a owl:Restriction ;
        owl:onProperty :part_of ;
        owl:someValuesFrom ?a ;
        owl:disjointWith [
          a owl:Restriction ;
          owl:onProperty :part_of ;
          owl:someValuesFrom ?b
        ]
      ]
    }
    WHERE {
      ?a :part_disjoint_with ?b .
    }</obo:IAO_0000112>
        <obo:IAO_0000115>Links an annotation property to a SPARQL CONSTRUCT query which is meant to provide semantics for a shortcut relation.</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/ontodev/robot/issues/963"/>
        <dc:contributor rdf:resource="https://orcid.org/0000-0002-7356-1779"/>
        <dc:contributor rdf:resource="https://orcid.org/0000-0002-8688-6599"/>
        <rdfs:label>defined by construct</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003000 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003000">
        <obo:IAO_0000112>CHEBI:26523 (reactive oxygen species) has an exact synonym (ROS), which is of type OMO:0003000 (abbreviation)</obo:IAO_0000112>
        <obo:IAO_0000115>A synonym type for describing abbreviations or initalisms</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
        <rdfs:label>abbreviation</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003001 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003001">
        <obo:IAO_0000115>A synonym type for describing ambiguous synonyms</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
        <rdfs:label>ambiguous synonym</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003002 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003002">
        <obo:IAO_0000115>A synonym type for describing dubious synonyms</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
        <rdfs:label>dubious synonym</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003003 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003003">
        <obo:IAO_0000112>EFO:0006346 (severe cutaneous adverse reaction) has an exact synonym (scar), which is of the type OMO:0003003 (layperson synonym)</obo:IAO_0000112>
        <obo:IAO_0000115>A synonym type for describing layperson or colloquial synonyms</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
        <rdfs:label>layperson synonym</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003004 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003004">
        <obo:IAO_0000112>CHEBI:23367 (molecular entity) has an exact synonym (molecular entities), which is of the type OMO:0003004 (plural form)</obo:IAO_0000112>
        <obo:IAO_0000115>A synonym type for describing pluralization synonyms</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
        <rdfs:label>plural form</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003005 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003005">
        <obo:IAO_0000112>CHEBI:16189 (sulfate) has an exact synonym (sulphate), which is of the type OMO:0003005 (UK spelling synonym)</obo:IAO_0000112>
        <obo:IAO_0000115>A synonym type for describing UK spelling variants</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/122"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
        <rdfs:label>UK spelling synonym</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003006 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003006">
        <obo:IAO_0000115>A synonym type for common misspellings</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/132"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
        <rdfs:label>misspelling</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003007 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003007">
        <obo:IAO_0000115>A synonym type for misnomers, i.e., a synonym that is not technically correct but is commonly used anyway</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/133"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-03-03</terms:created>
        <rdfs:label>misnomer</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003008 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003008">
        <obo:IAO_0000112>MAPT, the gene that encodes the Tau protein, has a previous name DDPAC. Note: in this case, the name type is more specifically the gene symbol.</obo:IAO_0000112>
        <obo:IAO_0000115>A synonym type for names that have been used as primary labels in the past.</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/139"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-07-25</terms:created>
        <rdfs:label>previous name</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003009 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003009">
        <obo:IAO_0000112>The legal name for Harvard University (https://ror.org/03vek6s52) is President and Fellows of Harvard College</obo:IAO_0000112>
        <obo:IAO_0000115>A synonym type for the legal entity name</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/141"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-07-27</terms:created>
        <rdfs:label>legal name</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003010 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003010">
        <obo:IAO_0000112>CHEBI:46195 has been assigned the english International Nonproproprietary Name (INN) &quot;paracetamol&quot;. In some cases such as this one, the INN might be the same as the ontology&apos;s primary label</obo:IAO_0000112>
        <obo:IAO_0000115>The International Nonproprietary Name (INN) is a standardize name for a pharmaceutical drug or active ingredient issued by the World Health Organization (WHO) meant to address the issues with country- or language-specific brand names. These are issued in several languages, including English, Latin, French, Russian, Spanish, Arabic, and Chinese.</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/149"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-09-30</terms:created>
        <oboInOwl:hasExactSynonym>INN</oboInOwl:hasExactSynonym>
        <rdfs:label>International Nonproprietary Name</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003011 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003011">
        <obo:IAO_0000112>nasopharynx (UBERON:0001728) has the latin name &quot;pars nasalis pharyngis</obo:IAO_0000112>
        <obo:IAO_0000115>A synonym type for describing Latin term synonyms.</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/146"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0002-1773-2692"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-10-12</terms:created>
        <rdfs:label>latin term</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0003012 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0003012">
        <obo:IAO_0000112>NASA is an word acronym for the US National Aeronautics and Space Administration because the acronym is pronounced. FBI is an initialism (also known as alphabetism) for the US Federal Bureau of Investigation since the letters are pronounced one at a time. JPEG is an acronym for Joint Photographic Experts Group but does not count as a word acronym nor an initialism since it is mixed how it is pronounced.</obo:IAO_0000112>
        <obo:IAO_0000115>A synonym type for describing abbreviations that are a part of the full name&apos;s words, such as initialisms or alphabetisms.</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/135"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-4423-4370"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2023-11-01</terms:created>
        <rdfs:label>acronym</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0004000 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OMO_0004000">
        <obo:IAO_0000112>A serial number such as &quot;12324X&quot;; a stop sign; a written proper name such as &quot;OBI</obo:IAO_0000112>
        <obo:IAO_0000115>An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity.</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/144"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0002-6523-4866"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2024-03-25</terms:created>
        <rdfs:label>has symbol</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0001900 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001900">
        <obo:IAO_0000115>An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.</obo:IAO_0000115>
        <rdfs:label>temporal interpretation</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002161 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002161">
        <obo:IAO_0000112>tooth SubClassOf &apos;never in taxon&apos; value &apos;Aves&apos;</obo:IAO_0000112>
        <obo:IAO_0000115>x never in taxon T if and only if T is a class, and x does not instantiate the class expression &quot;in taxon some T&quot;. Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL.</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/17921072"/>
        <obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20973947"/>
        <obo:IAO_0000425>Class: ?X DisjointWith: RO_0002162 some ?Y </obo:IAO_0000425>
        <obo:OMO_0002000>PREFIX rdfs: &lt;http://www.w3.org/2000/01/rdf-schema#&gt;
PREFIX owl: &lt;http://www.w3.org/2002/07/owl#&gt;
PREFIX in_taxon: &lt;http://purl.obolibrary.org/obo/RO_0002162&gt;
PREFIX never_in_taxon: &lt;http://purl.obolibrary.org/obo/RO_0002161&gt;
CONSTRUCT {
  in_taxon: a owl:ObjectProperty .
    a owl:Restriction ;
    owl:onProperty in_taxon: ;
    owl:someValuesFrom ?taxon
  ] .
  ?x rdfs:subClassOf [
    a owl:Restriction ;
    owl:onProperty in_taxon: ;
    owl:someValuesFrom [
      a owl:Class ;
      owl:complementOf ?taxon
    ]
  ] .
}
WHERE {
  ?x never_in_taxon: ?taxon .
}</obo:OMO_0002000>
        <rdfs:label>never in taxon</rdfs:label>
        <rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002171 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002171">
        <obo:IAO_0000115>A is mutually_spatially_disjoint_with B if both A and B are classes, and there exists no p such that p is part_of some A and p is part_of some B.</obo:IAO_0000115>
        <obo:IAO_0000118>non-overlapping with</obo:IAO_0000118>
        <obo:IAO_0000118>shares no parts with</obo:IAO_0000118>
        <obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
        <obo:IAO_0000425>Class: &lt;http://www.w3.org/2002/07/owl#Nothing&gt; EquivalentTo: (BFO_0000050 some ?X) and (BFO_0000050 some ?Y)</obo:IAO_0000425>
        <obo:OMO_0002000>PREFIX owl: &lt;http://www.w3.org/2002/07/owl#&gt;
PREFIX part_of: &lt;http://purl.obolibrary.org/obo/BFO_0000050&gt;
PREFIX mutually_spatially_disjoint_with: &lt;http://purl.obolibrary.org/obo/RO_0002171&gt;
CONSTRUCT {
  part_of: a owl:ObjectProperty .
  [
    a owl:Restriction ;
    owl:onProperty part_of: ;
    owl:someValuesFrom ?x ;
      a owl:Restriction ;
      owl:onProperty part_of: ;
      owl:someValuesFrom ?y
    ]
  ]
}
WHERE {
  ?x mutually_spatially_disjoint_with: ?y .
}</obo:OMO_0002000>
        <rdfs:label xml:lang="en">mutually spatially disjoint with</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/RO_0002163"/>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern</rdfs:seeAlso>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002172 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002172">
        <obo:IAO_0000115>An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">taxonomic class assertion</rdfs:label>
        <rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002175 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002175">
        <obo:IAO_0000115>S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
        <obo:OMO_0002000>PREFIX rdfs: &lt;http://www.w3.org/2000/01/rdf-schema#&gt;
PREFIX owl: &lt;http://www.w3.org/2002/07/owl#&gt;
PREFIX in_taxon: &lt;http://purl.obolibrary.org/obo/RO_0002162&gt;
PREFIX present_in_taxon: &lt;http://purl.obolibrary.org/obo/RO_0002175&gt;
CONSTRUCT {
  in_taxon: a owl:ObjectProperty .
  ?witness rdfs:label ?label .
  ?witness rdfs:subClassOf ?x .
  ?witness rdfs:subClassOf [
    a owl:Restriction ;
    owl:onProperty in_taxon: ;
    owl:someValuesFrom ?taxon
  ] .
}
WHERE {
  ?x present_in_taxon: ?taxon .
  BIND(IRI(CONCAT(
    &quot;http://purl.obolibrary.org/obo/RO_0002175#&quot;,
    MD5(STR(?x)),
    &quot;-&quot;,
    MD5(STR(?taxon))
  )) as ?witness)
  BIND(CONCAT(STR(?x), &quot; in taxon &quot;, STR(?taxon)) AS ?label)
}</obo:OMO_0002000>
        <rdfs:comment>The SPARQL expansion for this relation introduces new named classes into the ontology. For this reason it is likely that the expansion should only be performed during a QC pipeline; the expanded output should usually not be included in a published version of the ontology.</rdfs:comment>
        <rdfs:label xml:lang="en">present in taxon</rdfs:label>
        <rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002416 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002416">
        <obo:IAO_0000115>An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">logical macro assertion</rdfs:label>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://purl.obolibrary.org/obo/ro/docs/shortcut-relations/</rdfs:seeAlso>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002420 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002420">
        <obo:IAO_0000115>A logical macro assertion whose domain is an IRI for a class</obo:IAO_0000115>
        <obo:IAO_0000116>The domain for this class can be considered to be owl:Class, but we cannot assert this in OWL2-DL</obo:IAO_0000116>
        <rdfs:label xml:lang="en">logical macro assertion on a class</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002421 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002421">
        <obo:IAO_0000115>A logical macro assertion whose domain is an IRI for a property</obo:IAO_0000115>
        <rdfs:label xml:lang="en">logical macro assertion on a property</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002422 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002422">
        <obo:IAO_0000115>Used to annotate object properties to describe a logical meta-property or characteristic of the object property.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">logical macro assertion on an object property</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002421"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002601 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002601">
        <obo:IAO_0000115>A shortcut relationship that holds between two entities based on their identity criteria</obo:IAO_0000115>
        <rdfs:label>logical macro assertion involving identity</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002602 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002602">
        <obo:IAO_0000115>A shortcut relationship between two entities x and y1, such that the intent is that the relationship is functional and inverse function, but there is no guarantee that this property holds.</obo:IAO_0000115>
        <rdfs:label>in approximate one to one relationship with</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002601"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002604 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002604">
        <obo:IAO_0000112>&apos;anterior end of organism&apos; is-opposite-of &apos;posterior end of organism&apos;</obo:IAO_0000112>
        <obo:IAO_0000112>&apos;increase in temperature&apos; is-opposite-of &apos;decrease in temperature&apos;</obo:IAO_0000112>
        <obo:IAO_0000115>x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) &lt;= M(x,y) or M(y,z) &lt;= M(y,x).</obo:IAO_0000115>
        <rdfs:label>is opposite of</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002602"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/UBPROP_0000001 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000001">
        <rdfs:label>external_definition</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/UBPROP_0000002 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000002">
        <rdfs:label>axiom_lost_from_external_ontology</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/UBPROP_0000003 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000003">
        <rdfs:label>homology_notes</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/UBPROP_0000007 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000007">
        <rdfs:label>has_relational_adjective</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/UBPROP_0000008 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000008">
        <rdfs:label>taxon_notes</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/UBPROP_0000011 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000011">
        <rdfs:label>development_notes</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/UBPROP_0000012 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000012">
        <rdfs:label>external_ontology_notes</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/UBPROP_0000202 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000202">
        <rdfs:label>fma_set_term</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001818 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001818">
        <obo:IAO_0000115>An annotation property that represents a matched vaccine identifier used in the VIOLIN database.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Omar Tibi</obo:IAO_0000117>
        <rdfs:label>VIOLIN vaccine ID</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003099 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003099">
        <obo:IAO_0000115>An annotation property that represents the trade name of a product.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>trade name</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003146 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003146">
        <obo:IAO_0000115>An annotation property that represents the active ingredient of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine active ingredient</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003147"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003147 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003147">
        <obo:IAO_0000115>An annotation property that represents the vaccine ingredient of a vaccine. Such an ingredient may not be active.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine ingredient</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003151 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003151">
        <obo:IAO_0000115>An annotation property that describes the dose information of a vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>vaccine dose annotation</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003158 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003158">
        <obo:IAO_0000112>The vaccine Prevnar (trade name) has a FDA-defined proper name: Pneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197 Protein). Reference:  https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm180017.htm</obo:IAO_0000112>
        <obo:IAO_0000115>An annotation property that represents the proper name of a vaccine, which is defined in an official way such as one defined by FDA.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete vaccine proper name</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003159 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003159">
        <obo:IAO_0000112>The vaccine Prevnar has the manufacturer: Wyeth Pharmaceuticals Inc. Reference: https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm180017.htm</obo:IAO_0000112>
        <obo:IAO_0000115>An annotation property that represents the manufacturer of a vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete vaccine manufacturer</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003160 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003160">
        <obo:IAO_0000112>The vaccine Prevnar has the indications:
- Immunization of infants 2, 4, 6 and 12-15 months of age to prevent invasive pneumococcal disease.
- Immunization of infants and toddlers against otitis media caused by vaccine serotypes.
Reference: https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm180017.htm</obo:IAO_0000112>
        <obo:IAO_0000115>An annotation property that represents the indications of a vaccine defined by the USA FDA.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>FDA vaccine indications</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003161 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003161">
        <obo:IAO_0000112>Prevnar has the package insert PDF URL: https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM137038.pdf . Recorded on 11/26/2018.</obo:IAO_0000112>
        <obo:IAO_0000115>An annotation property that represents a URL of the package insert PDF document of a licensed vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>vaccine package insert PDF URL</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003162 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003162">
        <obo:IAO_0000115>An annotation property that indicate the number that is generated by FDA based on a request from an applicant of a product licensing.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.fda.gov/downloads/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/ProceduresSOPPs/UCM461225.pdf</obo:IAO_0000119>
        <rdfs:label>vaccine STN</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003198 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003198">
        <rdfs:label>RxNorm ID</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003557 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003557">
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete has Protegen id</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003558 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003558">
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete has Protegen annotation</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003560 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003560">
        <obo:IAO_0000112>As seen: http://purl.bioontology.org/ontology/RXNORM/901644, the RxNORM vaccine term &quot;Prevnar 13 vaccine 0.5 ML Prefilled Syringe&quot; has Preferred Name of: 0.5 ML Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0088 MG/ML / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML Prefilled Syringe [Prevnar 13]&quot;. In this case, the whole preferred name is annotated under the annotation property &quot;RxNORM Preferred Name&quot;.</obo:IAO_0000112>
        <rdfs:label>RxNorm Preferred Name</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005279 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005279">
        <rdfs:label>RxNorm Synonym</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005328 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005328">
        <obo:IAO_0000115>An identifier assigned by the Vaccine Adjuvant Compendium (VAC: https://vac.niaid.nih.gov/)</obo:IAO_0000115>
        <obo:IAO_0000119>https://vac.niaid.nih.gov/</obo:IAO_0000119>
        <rdfs:label>VAC adjuvant ID</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005431 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005431">
        <obo:IAO_0000115>An annotation property that represents the annotated information about the antigens used for a specific vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Penny Pan</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Antigen</obo:IAO_0000119>
        <rdfs:label>vaccine antigen annotation</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005432 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005432">
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete vaccine preparation annotation</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005433 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005433">
        <rdfs:label>vaccine response annotation</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005438 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005438">
        <obo:IAO_0000115>An annotation property that refers to a specific CVX ID.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Penny Pan</obo:IAO_0000117>
        <obo:IAO_0000119>https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx</obo:IAO_0000119>
        <rdfs:label>CVX code</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005500 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005500">
        <obo:IAO_0000115>An annotation property that shows the status of vaccine developmeint including: clinical trial, research, licensed, or Emergency Use Authorization (EUA).</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Penny Pan</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete status of vaccine development</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010151 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0010151">
        <obo:IAO_0000115>An annotation property that represents an identifier of RxNorm or RxNorm extension concept assigned by OMOP.</obo:IAO_0000115>
        <rdfs:label>OMOP concept ID</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010152 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_0010152">
        <obo:IAO_0000115>An annotation property that represents an identifier of RxNorm extension term assigned by OMOP.</obo:IAO_0000115>
        <rdfs:label>RxNorm OMOP extension ID</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_1000000 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_1000000">
        <obo:IAO_0000115>An annotation property that refers to full vaccine name in CVX code set.</obo:IAO_0000115>
        <rdfs:label>CVX full vaccine name</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_1000001 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/VO_1000001">
        <obo:IAO_0000115>An annotation property that refers to short description in CVX code set.</obo:IAO_0000115>
        <rdfs:label>CVX short description</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/chebi/charge -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/charge"/>
    


    <!-- http://purl.obolibrary.org/obo/chebi/formula -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/formula"/>
    


    <!-- http://purl.obolibrary.org/obo/chebi/inchi -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchi"/>
    


    <!-- http://purl.obolibrary.org/obo/chebi/inchikey -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchikey"/>
    


    <!-- http://purl.obolibrary.org/obo/chebi/mass -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/mass"/>
    


    <!-- http://purl.obolibrary.org/obo/chebi/monoisotopicmass -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/monoisotopicmass"/>
    


    <!-- http://purl.obolibrary.org/obo/chebi/smiles -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/smiles"/>
    


    <!-- http://purl.obolibrary.org/obo/ncbitaxon#has_rank -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/ncbitaxon#has_rank">
        <rdfs:label>has_rank</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.org/dc/elements/1.1/contributor -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/contributor"/>
    


    <!-- http://purl.org/dc/elements/1.1/coverage -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/coverage"/>
    


    <!-- http://purl.org/dc/elements/1.1/creator -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/creator"/>
    


    <!-- http://purl.org/dc/elements/1.1/date -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/date"/>
    


    <!-- http://purl.org/dc/elements/1.1/description -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/description"/>
    


    <!-- http://purl.org/dc/elements/1.1/format -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/format"/>
    


    <!-- http://purl.org/dc/elements/1.1/identifier -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/identifier"/>
    


    <!-- http://purl.org/dc/elements/1.1/language -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/language"/>
    


    <!-- http://purl.org/dc/elements/1.1/license -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/license"/>
    


    <!-- http://purl.org/dc/elements/1.1/member -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/member"/>
    


    <!-- http://purl.org/dc/elements/1.1/publisher -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/publisher"/>
    


    <!-- http://purl.org/dc/elements/1.1/relation -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/relation"/>
    


    <!-- http://purl.org/dc/elements/1.1/rights -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/rights"/>
    


    <!-- http://purl.org/dc/elements/1.1/source -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/source"/>
    


    <!-- http://purl.org/dc/elements/1.1/subject -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/subject"/>
    


    <!-- http://purl.org/dc/elements/1.1/title -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/title"/>
    


    <!-- http://purl.org/dc/elements/1.1/type -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/type"/>
    


    <!-- http://purl.org/dc/terms/contributor -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/contributor"/>
    


    <!-- http://purl.org/dc/terms/created -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/created"/>
    


    <!-- http://purl.org/dc/terms/description -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/description"/>
    


    <!-- http://purl.org/dc/terms/license -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/license"/>
    


    <!-- http://purl.org/dc/terms/source -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/source"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#consider -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#consider"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#created_by -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#created_by"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#creation_date -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#creation_date"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#hasAlternativeId -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym">
        <obo:IAO_0000115>An alternative label for a class or property which has a more general meaning than the preferred name/primary label.</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
        <obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/18</obo:IAO_0000233>
        <rdfs:label xml:lang="en">has broad synonym</rdfs:label>
        <rdfs:seeAlso>https://github.com/information-artifact-ontology/ontology-metadata/issues/18</rdfs:seeAlso>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
    </owl:AnnotationProperty>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#hasDbXref -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref">
        <obo:IAO_0000112>disease characteristic (MONDO:0021125) has cross-reference (http://www.geneontology.org/formats/oboInOwl#hasDbXref) &quot;NCIT:C41009&quot;^^xsd:string</obo:IAO_0000112>
        <obo:IAO_0000115>An annotation property that links an ontology entity or a statement to a prefixed identifier or URI.</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/ontology-metadata/issues/123"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0002-7356-1779"/>
        <terms:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2024-03-18</terms:created>
        <rdfs:label>has cross-reference</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#hasExactSynonym -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym">
        <obo:IAO_0000115>An alternative label for a class or property which has the exact same meaning than the preferred name/primary label.</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
        <obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/20</obo:IAO_0000233>
        <rdfs:label xml:lang="en">has exact synonym</rdfs:label>
        <rdfs:seeAlso>https://github.com/information-artifact-ontology/ontology-metadata/issues/20</rdfs:seeAlso>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
    </owl:AnnotationProperty>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym">
        <obo:IAO_0000115>An alternative label for a class or property which has a more specific meaning than the preferred name/primary label.</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
        <obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/19</obo:IAO_0000233>
        <rdfs:label xml:lang="en">has narrow synonym</rdfs:label>
        <rdfs:seeAlso>https://github.com/information-artifact-ontology/ontology-metadata/issues/19</rdfs:seeAlso>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
    </owl:AnnotationProperty>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#hasOBONamespace -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym">
        <obo:IAO_0000115>An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct.</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
        <obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/21</obo:IAO_0000233>
        <rdfs:label xml:lang="en">has related synonym</rdfs:label>
        <rdfs:seeAlso>https://github.com/information-artifact-ontology/ontology-metadata/issues/21</rdfs:seeAlso>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
    </owl:AnnotationProperty>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#hasSynonym -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasSynonym"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#hasURI -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasURI"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#id -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#inSubset -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- http://www.w3.org/2000/01/rdf-schema#comment -->

    <owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#comment"/>
    


    <!-- http://www.w3.org/2000/01/rdf-schema#isDefinedBy -->

    <owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#isDefinedBy"/>
    


    <!-- http://www.w3.org/2000/01/rdf-schema#label -->

    <owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#label"/>
    


    <!-- http://www.w3.org/2000/01/rdf-schema#seeAlso -->

    <owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#seeAlso"/>
    


    <!-- http://www.w3.org/2004/02/skos/core#exactMatch -->

    <owl:AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
    


    <!-- http://www.w3.org/2004/02/skos/core#notation -->

    <owl:AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#notation"/>
    


    <!-- http://xmlns.com/foaf/0.1/depicted_by -->

    <owl:AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/depicted_by"/>
    


    <!-- http://xmlns.com/foaf/0.1/depiction -->

    <owl:AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/depiction"/>
    


    <!-- http://xmlns.com/foaf/0.1/homepage -->

    <owl:AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/homepage"/>
    


    <!-- http://xmlns.com/foaf/0.1/mbox -->

    <owl:AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/mbox"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://www.w3.org/1999/02/22-rdf-syntax-ns#PlainLiteral -->

    <rdfs:Datatype rdf:about="http://www.w3.org/1999/02/22-rdf-syntax-ns#PlainLiteral"/>
    


    <!-- http://www.w3.org/2000/01/rdf-schema#Literal -->

    <rdfs:Datatype rdf:about="http://www.w3.org/2000/01/rdf-schema#Literal"/>
    


    <!-- http://www.w3.org/2001/XMLSchema#date -->

    <rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#date"/>
    


    <!-- http://www.w3.org/2001/XMLSchema#dateTime -->

    <rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#dateTime"/>
    


    <!-- http://www.w3.org/2001/XMLSchema#float -->

    <rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#float"/>
    


    <!-- http://www.w3.org/2001/XMLSchema#integer -->

    <rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#integer"/>
    


    <!-- http://www.w3.org/2001/XMLSchema#nonNegativeInteger -->

    <rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#nonNegativeInteger"/>
    


    <!-- http://www.w3.org/2001/XMLSchema#string -->

    <rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#string"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <obo:IAO_0000111 xml:lang="en">is part of</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">my brain is part of my body (continuant parthood, two material entities)</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this day is part of this year (occurrent parthood)</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a core relation that holds between a part and its whole</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)

A continuant cannot be part of an occurrent: use &apos;participates in&apos;. An occurrent cannot be part of a continuant: use &apos;has participant&apos;. A material entity cannot be part of an immaterial entity: use &apos;has location&apos;. A specifically dependent continuant cannot be part of an independent continuant: use &apos;inheres in&apos;. An independent continuant cannot be part of a specifically dependent continuant: use &apos;bearer of&apos;.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">part_of</obo:IAO_0000118>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:label xml:lang="en">part of</rdfs:label>
        <rdfs:seeAlso>http://www.obofoundry.org/ro/#OBO_REL:part_of</rdfs:seeAlso>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000054 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000054">
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000055 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000055">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000062 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000062">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002086"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000063"/>
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:propertyChainAxiom rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062"/>
        </owl:propertyChainAxiom>
        <owl:propertyChainAxiom rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002091"/>
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062"/>
        </owl:propertyChainAxiom>
        <owl:propertyChainAxiom rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002092"/>
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062"/>
        </owl:propertyChainAxiom>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000063 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000063">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002222"/>
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:propertyChainAxiom rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063"/>
        </owl:propertyChainAxiom>
        <owl:propertyChainAxiom rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002092"/>
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063"/>
        </owl:propertyChainAxiom>
        <obo:IAO_0000111 xml:lang="en">precedes</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) &lt;= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">precedes</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000066 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000066">
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000067"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <owl:propertyChainAxiom rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
        </owl:propertyChainAxiom>
        <owl:propertyChainAxiom rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
        </owl:propertyChainAxiom>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000067 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000067">
        <obo:IAO_0000111 xml:lang="en">site of</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">[copied from inverse property &apos;occurs in&apos;] b occurs_in c =def b is a process and c is a material entity or immaterial entity&amp; there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.&amp; forall(t) if b exists_at t then c exists_at t &amp; there exist spatial regions s and s’ where &amp; b spatially_projects_onto s at t&amp; c is occupies_spatial_region s’ at t&amp; s is a proper_continuant_part_of s’ at t</obo:IAO_0000115>
        <rdfs:comment>Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant</rdfs:comment>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">contains process</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000133 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000133">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">process profile of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000136 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000136"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000142 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000142">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000293 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000293">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000295"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000295 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000295">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000299 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000299">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000304 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000304">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000835"/>
        <obo:IAO_0000111 xml:lang="en">is_manufactured_by</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">http://www.affymetrix.com/products/arrays/specific/hgu133.affx is_manufactered_by http://www.affymetrix.com/ (if we decide to use these URIs for the actual entities)</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the &quot;Manufacturer Role&quot;, and those people/and or machines were members or of directed by the organization to do this.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Liju Fan</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">has_make</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">has_manufacturer</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">is_manufactured_by</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000312 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000312">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000417 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000417">
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000833"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000643 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000643">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000833 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000833">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000111>objective_achieved_by</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.</obo:IAO_0000115>
        <obo:IAO_0000117>OBI</obo:IAO_0000117>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>objective_achieved_by</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0001938 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0001938">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002314"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000053 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000053">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#InverseFunctionalProperty"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
        <obo:IAO_0000111 xml:lang="en">bearer of</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">this apple is bearer of this red color</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this vase is bearer of this fragility</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">Inverse of characteristic_of</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">bearer_of</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">is bearer of</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:label xml:lang="en">has characteristic</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000056 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000056">
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000057 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000057">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000058 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000058">
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000015"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000020"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
        <obo:IAO_0000112 xml:lang="en">A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A relationship between a generically dependent continuant and a specifically dependent continuant or process, in which the generically dependent continuant depends on some independent continuant or process in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants or processes.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">is concretized as</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000059 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000059">
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000015"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000020"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
        <obo:IAO_0000112 xml:lang="en">A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A relationship between a specifically dependent continuant or process and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. Multiple specifically dependent continuants or processes can concretize the same generically dependent continuant.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">concretizes</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000079 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000079">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
        <obo:IAO_0000112 xml:lang="en">this catalysis function is a function of this enzyme</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">function_of</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">is function of</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:comment>This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.</rdfs:comment>
        <rdfs:label xml:lang="en">function of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000080 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000080">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
        <obo:IAO_0000112 xml:lang="en">this red color is a quality of this apple</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A quality inheres in its bearer at all times for which the quality exists.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">is quality of</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">quality_of</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:comment>This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.</rdfs:comment>
        <rdfs:label xml:lang="en">quality of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000081 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000081">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
        <obo:IAO_0000112 xml:lang="en">this investigator role is a role of this person</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">is role of</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">role_of</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:comment>This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.</rdfs:comment>
        <rdfs:label xml:lang="en">role of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000085 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000085">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000086 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000086">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000091 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000091">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000092"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000092 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000092">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
        <obo:IAO_0000115>inverse of has disposition</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/RO_0002259"/>
        <rdfs:comment>This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.</rdfs:comment>
        <rdfs:label xml:lang="en">disposition of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0001000 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001000">
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001001"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0001001 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001001">
        <obo:IAO_0000112 xml:lang="en">this parent cell derives into this cell (cell division)</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this parent nucleus derives into this nucleus (nuclear division)</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">This is a very general relation. More specific relations are preferred when applicable, such as &apos;directly develops into&apos;. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking &apos;derives from&apos; rather than the forward-looking &apos;derives into&apos;.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">derives_into</obo:IAO_0000118>
        <rdfs:label xml:lang="en">derives into</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0001015 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001015">
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <obo:IAO_0000111 xml:lang="en">is location of</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">my head is the location of my brain</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this cage is the location of this rat</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between two independent continuants, the location and the target, in which the target is entirely within the location</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">location_of</obo:IAO_0000118>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:label xml:lang="en">location of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0001025 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001025">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <rdfs:domain>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000004"/>
                    <owl:Class>
                        <owl:complementOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <rdfs:range>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000004"/>
                    <owl:Class>
                        <owl:complementOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
        <owl:annotatedProperty rdf:resource="http://www.w3.org/2000/01/rdf-schema#domain"/>
        <owl:annotatedTarget rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <obo:IAO_0000116>This is redundant with the more specific &apos;independent and not spatial region&apos; constraint. We leave in the redundant axiom for use with reasoners that do not use negation.</obo:IAO_0000116>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
        <owl:annotatedProperty rdf:resource="http://www.w3.org/2000/01/rdf-schema#range"/>
        <owl:annotatedTarget rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <obo:IAO_0000116>This is redundant with the more specific &apos;independent and not spatial region&apos; constraint. We leave in the redundant axiom for use with reasoners that do not use negation.</obo:IAO_0000116>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002000 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002000">
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002002"/>
        <obo:IAO_0000112 xml:lang="en">the surface of my skin is a 2D boundary of my body</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">2D_boundary_of</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">boundary of</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">is 2D boundary of</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">is boundary of</obo:IAO_0000118>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:label xml:lang="en">2D boundary of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002002 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002002">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
        <obo:IAO_0000112 xml:lang="en">my body has 2D boundary the surface of my skin</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">has boundary</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">has_2D_boundary</obo:IAO_0000118>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:label xml:lang="en">has 2D boundary</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002009 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002009">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
        <obo:IAO_0000115>A relation that applies between a cell(c) and a gene(g) , where the process of &apos;transcription, DNA templated (GO_0006351)&apos; is occuring in in cell c and that process has input gene g.</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-7073-9172"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <terms:description>x &apos;cell expresses&apos; y iff:
cell(x)
AND gene(y)
AND exists some &apos;transcription, DNA templated (GO_0006351)&apos;(t)
AND t occurs_in x
AND t has_input y</terms:description>
        <rdfs:label>cell expresses</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002086 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002086">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002222"/>
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/ro/subsets#ro-eco"/>
        <rdfs:comment xml:lang="en">X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)</rdfs:comment>
        <rdfs:label xml:lang="en">ends after</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002091 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002091">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002222"/>
        <obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
        <obo:IAO_0000118>io</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/ro/subsets#ro-eco"/>
        <rdfs:comment xml:lang="en">X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))</rdfs:comment>
        <rdfs:label xml:lang="en">starts during</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002092 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002092">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002091"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002093"/>
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
        <obo:IAO_0000118>d</obo:IAO_0000118>
        <obo:IAO_0000118>during</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/valid_for_go_annotation_extension"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/valid_for_go_ontology"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/valid_for_gocam"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/ro/subsets#ro-eco"/>
        <rdfs:comment xml:lang="en">X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))</rdfs:comment>
        <rdfs:label xml:lang="en">happens during</rdfs:label>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://wiki.geneontology.org/Happens_during</rdfs:seeAlso>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002093 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002093">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002222"/>
        <obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
        <obo:IAO_0000118>o</obo:IAO_0000118>
        <obo:IAO_0000118>overlaps</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/ro/subsets#ro-eco"/>
        <rdfs:comment xml:lang="en">X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). </rdfs:comment>
        <rdfs:label xml:lang="en">ends during</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002162 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002162">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002320"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002180 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002180">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002204 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002204">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115>definition &quot;x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x&quot;</obo:IAO_0000115>
        <obo:IAO_0000116>We would like to be able to express the rule: if t transcribed from g, and t is a noncoding RNA and has an evolved function, then t has gene product g.</obo:IAO_0000116>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">gene product of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002205 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002205">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
        <obo:IAO_0000112>every HOTAIR lncRNA is the gene product of some HOXC gene</obo:IAO_0000112>
        <obo:IAO_0000112>every sonic hedgehog protein (PR:000014841) is the gene product of some sonic hedgehog gene</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115>x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">has gene product</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002206 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002206">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
        <obo:IAO_0000112>&apos;neural crest cell&apos;  SubClassOf expresses some &apos;Wnt1 gene&apos;</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115>x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">expressed in</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002222 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002222">
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000119 rdf:resource="https://en.wikipedia.org/wiki/Allen%27s_interval_algebra"/>
        <obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <terms:source rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1</terms:source>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/ro/subsets#ro-eco"/>
        <rdfs:comment>A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.</rdfs:comment>
        <rdfs:label xml:lang="en">temporally related to</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002245 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002245">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002206"/>
        <obo:IAO_0000115>g is over-expressed in t iff g is expressed in t, and the expression level of g is increased relative to some background.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>over-expressed in</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002246 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002246">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002206"/>
        <obo:IAO_0000115>g is under-expressed in t iff g is expressed in t, and the expression level of g is decreased relative to some background.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>under-expressed in</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002260 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002260">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
        <obo:IAO_0000115>c has-biological-role r iff c has-role r and r is a biological role (CHEBI:24432)</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>has biological role</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002261 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002261">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
        <obo:IAO_0000115>c has-application-role r iff c has-role r and r is an application role (CHEBI:33232)</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>has application role</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002262 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002262">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
        <obo:IAO_0000115>c has-chemical-role r iff c has-role r and r is a chemical role (CHEBI:51086)</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>has chemical role</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002291 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002291">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002206"/>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115>x is ubiquitously expressed in y if and only if x is expressed in y, and the majority of cells in y express x</obo:IAO_0000115>
        <obo:IAO_0000116>Revisit this term after coordinating with SO/SOM. The domain of this relation should be a sequence, as an instance of a DNA molecule is only expressed in the cell of which it is a part.</obo:IAO_0000116>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">ubiquitously expressed in</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002292 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002292">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002293 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002293">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115>inverse of ubiquiotously expressed in</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/RO_0002259"/>
        <rdfs:label xml:lang="en">ubiquitously expresses</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002314 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002314">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002502"/>
        <obo:IAO_0000115>q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.</obo:IAO_0000115>
        <obo:IAO_0000116>Because part_of is transitive, inheres in is a sub-relation of characteristic of part of</obo:IAO_0000116>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000118>inheres in part of</obo:IAO_0000118>
        <obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20064205"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:label xml:lang="en">characteristic of part of</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/ro/docs/reflexivity/"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002320 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002320">
        <obo:IAO_0000115>A relationship that holds via some environmental process</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">evolutionarily related to</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002330 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002330">
        <obo:IAO_0000115>holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts.</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">genomically related to</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002350 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002350">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002351"/>
        <obo:IAO_0000112>An organism that is a member of a population of organisms</obo:IAO_0000112>
        <obo:IAO_0000115>is member of is a mereological relation between a item and a collection.</obo:IAO_0000115>
        <obo:IAO_0000118>is member of</obo:IAO_0000118>
        <obo:IAO_0000118>member part of</obo:IAO_0000118>
        <obo:IAO_0000119>SIO</obo:IAO_0000119>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:label xml:lang="en">member of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002351 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002351">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#IrreflexiveProperty"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002410 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002410">
        <obo:IAO_0000115>relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.</obo:IAO_0000115>
        <obo:IAO_0000116>This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an &apos;activity flow-centric approach&apos;, with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.

To define causal relations in an activity-flow type network, we make use of 3 primitives:

 * Temporal: how do the intervals of the two occurrents relate? 
 * Is the causal relation regulatory?
 * Is the influence positive or negative?

The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are &apos;direct&apos;, &apos;indirect&apos; or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under &apos;temporally related to&apos;). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.

For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.

For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.

Each of these 3 primitives can be composed to yield a cross-product of different relation types.</obo:IAO_0000116>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">causally related to</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002502 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002502">
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>depends on</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/BFO_0000169"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002503 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002503">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002502"/>
        <obo:IAO_0000115>q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2</obo:IAO_0000115>
        <obo:IAO_0000116>This relation is provided in order to support the use of relational qualities such as &apos;concentration of&apos;; for example, the concentration of C in V is a quality that inheres in V, but pertains to C.</obo:IAO_0000116>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20064205"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>towards</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002510 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002510">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
        <obo:IAO_0000115>x is transcribed from y if and only if x is synthesized from template y</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>transcribed from</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002511 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002511">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
        <obo:IAO_0000115>inverse of transcribed from</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/RO_0002259"/>
        <rdfs:label>transcribed to</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002512 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002512">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
        <obo:IAO_0000115>x is the ribosomal translation of y if and only if a ribosome reads x through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces y</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>ribosomal translation of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002513 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002513">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
        <obo:IAO_0000115>inverse of ribosomal translation of</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label>ribosomally translates to</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0004017 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004017">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:created_by rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-11-05T03:20:01Z</oboInOwl:creation_date>
        <rdfs:label>realizable has basis in</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0004019 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004019">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0004017"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0004023"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0004023 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004023">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0040035"/>
        <obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all of which have a disease as the subject.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:created_by rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-11-05T03:50:54Z</oboInOwl:creation_date>
        <rdfs:label>causal relationship with disease as subject</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0004096 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004096">
        <rdfs:comment>DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information.</rdfs:comment>
        <rdfs:label xml:lang="en">DEPRECATED inheres in</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0004097 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004097">
        <rdfs:label xml:lang="en">DEPRECATED bearer of</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0040035 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0040035">
        <obo:IAO_0000115>This relation groups  relations between diseases and any other kind of entity.</obo:IAO_0000115>
        <obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, in which the subject or object is a disease.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:created_by rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-09-26T00:00:32Z</oboInOwl:creation_date>
        <rdfs:label>disease relationship</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000016 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000016">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000520"/>
        <obo:IAO_0000115>A type of &apos;has vaccine component&apos; relation that specifies a vaccine conjugate protein for a specific vaccine</obo:IAO_0000115>
        <rdfs:label>has vaccine conjugate protein</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000138 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000138">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000530"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
        <obo:IAO_0000115>A type of &apos;has vaccine vector&apos; relation that specifies a bacterial vaccine vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has bacterial vaccine vector</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000270 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000270">
        <obo:IAO_0000115>A relation that specifies contraindication of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000116>This relation may be replaced by has_vaccine_allergen. We need to determine if any vaccine contraindicator is not a vaccine allergen.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine contraindication</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000281 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000281">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000530"/>
        <obo:IAO_0000115>A type of &apos;has vaccine vector&apos; that is specifically for viral vaccine vector</obo:IAO_0000115>
        <rdfs:label>has viral vaccine vector</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000369 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000369">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000520"/>
        <obo:IAO_0000115>A &apos;has vaccine component&apos; relation that specifies the plasmid used for development of a particular DNA vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has DNA vaccine plasmid</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000445 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000445">
        <obo:IAO_0000115>A relation between a disorder and an infectious pathogen.</obo:IAO_0000115>
        <obo:IAO_0000116>The relation &apos;infection_of&apos; is introduced to represent an infection caused by an infectious pathogen. A pathogen infection is a disorder. Since the number of pathogens is large, there are numerous infections. To make the description of a specific infection simple, the shortcut term &apos;infection_of&apos; is defined: 
infection_of X = infection and has_part some (organism X and has_disposition some infectious disposition)</obo:IAO_0000116>
        <obo:IAO_0000117>Alan Ruttenburg</obo:IAO_0000117>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>infection_of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000462 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000462">
        <obo:IAO_0000115>An object property that specifies a process that is induced by vaccination of a vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>induced by vaccination of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000476 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000476">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000520"/>
        <obo:IAO_0000115>A &apos;has vaccine component&apos; relation that specifies a gene inserted to DNA vaccine plasmid for development of a particular DNA vaccine, and this gene encodes for a protein antigen. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has DNA vaccine antigen gene</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000520 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000520">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <obo:IAO_0000115>An object property that defines a relation between a vaccine and its component</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine component</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000524 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000524">
        <obo:IAO_0000115>An object property that specifies a vaccine antigen</obo:IAO_0000115>
        <obo:IAO_0000116>This relation only works for those vaccine antigen that is physically part of a vaccine preparation. It does not include those antigens that are not part of vaccine. For example, a protein antigen expressed in a DNA vaccine is not a part of vaccine pe ser. In this case, the vaccine expresses the protein, but the gene is part of the vaccine, not the protein. For the case, we can use the relation &apos;DNA vaccine expresses protein antigen&apos; under the relation &apos;expresses&apos;. </obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine antigen</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000525 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000525">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000524"/>
        <obo:IAO_0000115>A type of &apos;has vaccine antigen&apos; relation that is specifically for vaccine protective protein antigen used in subunit vaccine development</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has subunit vaccine antigen</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000527 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000527">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000524"/>
        <obo:IAO_0000115>A type of &apos;has vaccine antigen&apos; relation that is specifically for vaccine protective antigen component</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine protective antigen</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000529 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000529">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000520"/>
        <obo:IAO_0000115>A type of &apos;has vaccine component&apos; relation that is specifically for vaccine adjuvant component</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine adjuvant</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000530 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000530">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000520"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/VO_0000599"/>
        <obo:IAO_0000115>A type of &apos;has vaccine component&apos; relation that is specifically for vaccine vector component</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine vector</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000531 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000531"/>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000537 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000537">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <obo:IAO_0000115>An object property that indicates a secretion of a material (e.g., protein) from a vaccine organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>vaccine organism secretes</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000538 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000538">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000520"/>
        <obo:IAO_0000115>A &apos;has vaccine component&apos; relation that is specifically used for vaccine preservative</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine preservative</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000547 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000547">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000553 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000553">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <obo:IAO_0000115>An object property that specifies a relation between a vaccine and its vaccinee</obo:IAO_0000115>
        <rdfs:label>has vaccinee</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000608 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000608">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
        <obo:IAO_0000115>An &apos;expresses&apos; relation that specifies a relation between a DNA vaccine and a  protein antigen to be expressed by the DNA vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>DNA vaccine expresses protein antigen</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000638 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000638">
        <obo:IAO_0000112>&quot;A vaccinates B&quot; means that the vaccine A is used for vaccinating the host B (e.g., human).</obo:IAO_0000112>
        <obo:IAO_0000115>A relation between a vaccine instance and an organism type such that if the vaccine instance is given to an instance of the organism by the process vaccination, then it changes the organism&apos;s disposition to have an immune response against a disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Alan Ruttenburg</obo:IAO_0000117>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>obsolete vaccinates</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000711 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000711">
        <obo:IAO_0000115>has_vaccine_allegen is a relation that specifies an allegen to a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>obsolete has_vaccine_allergen</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000799 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000799">
        <obo:IAO_0000115>An object property that represents a mutational relation between a vaccine organism and another material (e.g., gene or protein). the mutated material initially exists in the original wildtype organism. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>vaccine organism has mutation</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000818 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000818">
        <obo:IAO_0000115>An object property that specifies a relation between a vaccine and a vaccine virmugen. </obo:IAO_0000115>
        <obo:IAO_0000116>This is a shortcut relation.
Domain: vaccine
Range: a gene

Shortcut:
is_specified_output_of some 
(&apos;preparation of gene mutant vaccine&apos; and (has_specified_input some gene))</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine virmugen</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000894 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000894">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000525"/>
        <obo:IAO_0000115>A &apos;has subunit vaccine antigen&apos; relation that indicates the antigen is protective.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has subunit vaccine protective antigen</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000908 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0000908">
        <obo:IAO_0000115>A relation that specifies a company that distributes a product (e.g., vaccine). The company is very likely not the manufacturer of the product.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>is_distributed_by</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001011 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001011">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/DOID_4"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001039 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001039"/>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001243 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0001243">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:range>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001274"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003127 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003127">
        <obo:IAO_0000115>An object property that represents a relation between a vaccine with a prime-boost schedule and a vaccine used for priming.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has prime vaccine</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003128 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003128">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <obo:IAO_0000115>An object property that represents a relation between a vaccine with a prime-boost schedule and a vaccine used for boost.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has boost vaccine</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003355 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003355">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:range>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000718"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003390 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0003390">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004909 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0004909">
        <obo:IAO_0000115>A shortcut object property that represents a relation between a vaccine and a disease process where the vaccine immunizes a host against a disease process.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete immunizes against disease process</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005242 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005242">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <obo:IAO_0000115>An object property that represents a relation between a material entity and biological process</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>up-expressed as immune signature of</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005312 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005312"/>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005377 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005377"/>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005481 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005481">
        <obo:IAO_0000115>A relation between a material entity  and a parasite where the material entity causes some process against some parasite such that transmitting to additional hosts or vectors.</obo:IAO_0000115>
        <rdfs:label>capable of blocking transmission (of life cycle)</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005561 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005561">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005481"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005562 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0005562"/>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010396 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0010396">
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000233>flu season</obo:IAO_0000233>
        <rdfs:label>has flu season</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015002 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0015002">
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000233>brand name</obo:IAO_0000233>
        <rdfs:label>has drug brand name</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015007 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0015007"/>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015018 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0015018">
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000233>drug package</obo:IAO_0000233>
        <rdfs:label>has drug package</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015021 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/VO_0015021">
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000233>organization</obo:IAO_0000233>
        <rdfs:label>has drug supplier</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000001">
        <rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000001</metadata:prefixIRI>
        <obo:BFO_0000179>entity</obo:BFO_0000179>
        <obo:BFO_0000180>Entity</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">Julius Caesar</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">Verdi’s Requiem</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the Second World War</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">your body mass index</obo:IAO_0000112>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Entity doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. For example Werner Ceusters &apos;portions of reality&apos; include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, &apos;How to track absolutely everything&apos; at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])</obo:IAO_0000600>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">entity</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget xml:lang="en">Entity doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. For example Werner Ceusters &apos;portions of reality&apos; include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, &apos;How to track absolutely everything&apos; at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000004"/>
        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
        <rdfs:seeAlso rdf:resource="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/001-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:disjointWith>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
            </owl:Restriction>
        </owl:disjointWith>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000002</metadata:prefixIRI>
        <obo:BFO_0000179>continuant</obo:BFO_0000179>
        <obo:BFO_0000180>Continuant</obo:BFO_0000180>
        <obo:IAO_0000115 xml:lang="en">An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Continuant doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster&apos;s other portions of reality, questions are raised as to whether universals are continuants</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])</obo:IAO_0000600>
        <obo:IAO_0000601 xml:lang="en">if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">continuant</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget xml:lang="en">Continuant doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster&apos;s other portions of reality, questions are raised as to whether universals are continuants</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000007"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/008-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/126-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/009-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/011-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/009-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/126-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/008-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/011-002"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000001"/>
        <owl:disjointWith>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
            </owl:Restriction>
        </owl:disjointWith>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000003</metadata:prefixIRI>
        <obo:BFO_0000179>occurrent</obo:BFO_0000179>
        <obo:BFO_0000180>Occurrent</obo:BFO_0000180>
        <obo:IAO_0000115 xml:lang="en">An entity that has temporal parts and that happens, unfolds or develops through time.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Occurrent doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.</obo:IAO_0000116>
        <obo:IAO_0000116>Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by &apos;spn[e]&apos; and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write &apos;spr[e]&apos; and `spl[e]&apos; respectively for the spread and spell of e, omitting mention of the frame.</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])</obo:IAO_0000600>
        <obo:IAO_0000601 xml:lang="en">Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">occurrent</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget xml:lang="en">Occurrent doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000006"/>
        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget>Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by &apos;spn[e]&apos; and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write &apos;spr[e]&apos; and `spl[e]&apos; respectively for the spread and spell of e, omitting mention of the frame.</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000012"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/077-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/108-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/079-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/108-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/079-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000004</metadata:prefixIRI>
        <obo:BFO_0000179>ic</obo:BFO_0000179>
        <obo:BFO_0000180>IndependentContinuant</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">a chair</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a heart</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a leg</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a molecule</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a spatial region</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">an atom</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">an orchestra.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">an organism</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the bottom right portion of a human torso</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the interior of your mouth</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])</obo:IAO_0000115>
        <obo:IAO_0000601 xml:lang="en">For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] </obo:IAO_0000602>
        <rdfs:comment xml:lang="en">A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.</rdfs:comment>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">independent continuant</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
        <owl:annotatedTarget xml:lang="en">b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/017-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/134-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/018-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/134-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/018-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/017-002"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000006</metadata:prefixIRI>
        <obo:BFO_0000179>s-region</obo:BFO_0000179>
        <obo:BFO_0000180>SpatialRegion</obo:BFO_0000180>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Spatial regions do not participate in processes.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Spatial region doesn&apos;t have a closure axiom because the subclasses don&apos;t exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn&apos;t overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])</obo:IAO_0000600>
        <obo:IAO_0000601 xml:lang="en">All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">spatial region</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget xml:lang="en">Spatial region doesn&apos;t have a closure axiom because the subclasses don&apos;t exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn&apos;t overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000002"/>
        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/035-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/036-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/036-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/035-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000008">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000008</metadata:prefixIRI>
        <obo:BFO_0000179>t-region</obo:BFO_0000179>
        <obo:BFO_0000180>TemporalRegion</obo:BFO_0000180>
        <obo:IAO_0000116 xml:lang="en">Temporal region doesn&apos;t have a closure axiom because the subclasses don&apos;t exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn&apos;t overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])</obo:IAO_0000600>
        <obo:IAO_0000601 xml:lang="en">All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">temporal region</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget xml:lang="en">Temporal region doesn&apos;t have a closure axiom because the subclasses don&apos;t exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn&apos;t overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000003"/>
        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/100-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/101-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/119-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/119-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/101-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/100-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000009</metadata:prefixIRI>
        <obo:BFO_0000179>2d-s-region</obo:BFO_0000179>
        <obo:BFO_0000180>TwoDimensionalSpatialRegion</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">an infinitely thin plane in space.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the surface of a sphere-shaped part of space</obo:IAO_0000112>
        <obo:IAO_0000600 xml:lang="en">A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">two-dimensional spatial region</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000009"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/039-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000009"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/039-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000011</metadata:prefixIRI>
        <obo:BFO_0000179>st-region</obo:BFO_0000179>
        <obo:BFO_0000180>SpatiotemporalRegion</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">the spatiotemporal region occupied by a human life</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the spatiotemporal region occupied by a process of cellular meiosis.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the spatiotemporal region occupied by the development of a cancer tumor</obo:IAO_0000112>
        <obo:IAO_0000600 xml:lang="en">A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])</obo:IAO_0000600>
        <obo:IAO_0000601 xml:lang="en">All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">Every spatiotemporal region occupies_spatiotemporal_region itself.</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">spatiotemporal region</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/095-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/096-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/099-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/098-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/107-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/107-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/099-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/096-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/095-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000011"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/098-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000015">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000015</metadata:prefixIRI>
        <obo:BFO_0000179>process</obo:BFO_0000179>
        <obo:BFO_0000180>Process</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">a process of cell-division, \ a beating of the heart</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a process of meiosis</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a process of sleeping</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the course of a disease</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the flight of a bird</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the life of an organism</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">your process of aging.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)</obo:IAO_0000116>
        <obo:IAO_0000602>(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] </obo:IAO_0000602>
        <rdfs:comment xml:lang="en">An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.</rdfs:comment>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">process</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
        <owl:annotatedTarget xml:lang="en">p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/083-003"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/083-003"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000016</metadata:prefixIRI>
        <obo:BFO_0000179>disposition</obo:BFO_0000179>
        <obo:BFO_0000180>Disposition</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">an atom of element X has the disposition to decay to an atom of element Y</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">certain people have a predisposition to colon cancer</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">children are innately disposed to categorize objects in certain ways.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the cell wall is disposed to filter chemicals in endocytosis and exocytosis</obo:IAO_0000112>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">b is a disposition means: b is a realizable entity &amp; b’s bearer is some material entity &amp; b is such that if it ceases to exist, then its bearer is physically changed, &amp; b’s realization occurs when and because this bearer is in some special physical circumstances, &amp; this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])</obo:IAO_0000600>
        <obo:IAO_0000601 xml:lang="en">If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">disposition</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">b is a disposition means: b is a realizable entity &amp; b’s bearer is some material entity &amp; b is such that if it ceases to exist, then its bearer is physically changed, &amp; b’s realization occurs when and because this bearer is in some special physical circumstances, &amp; this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/062-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/063-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/063-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/062-002"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000017</metadata:prefixIRI>
        <obo:BFO_0000179>realizable</obo:BFO_0000179>
        <obo:BFO_0000180>RealizableEntity</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">the disposition of this piece of metal to conduct electricity.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the disposition of your blood to coagulate</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the function of your reproductive organs</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the role of being a doctor</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the role of this boundary to delineate where Utah and Colorado meet</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.</obo:IAO_0000115>
        <obo:IAO_0000600 xml:lang="en">To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])</obo:IAO_0000600>
        <obo:IAO_0000601 xml:lang="en">All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">realizable entity</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/058-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/060-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/060-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/058-002"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000018</metadata:prefixIRI>
        <obo:BFO_0000179>0d-s-region</obo:BFO_0000179>
        <obo:BFO_0000180>ZeroDimensionalSpatialRegion</obo:BFO_0000180>
        <obo:IAO_0000600 xml:lang="en">A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">zero-dimensional spatial region</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000018"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/037-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000018"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/037-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000019</metadata:prefixIRI>
        <obo:BFO_0000179>quality</obo:BFO_0000179>
        <obo:BFO_0000180>Quality</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">the ambient temperature of this portion of air</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the color of a tomato</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the length of the circumference of your waist</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the mass of this piece of gold.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the shape of your nose</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the shape of your nostril</obo:IAO_0000112>
        <obo:IAO_0000600 xml:lang="en">a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])</obo:IAO_0000600>
        <obo:IAO_0000601 xml:lang="en">If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">quality</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/055-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/105-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/055-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/105-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000020</metadata:prefixIRI>
        <obo:BFO_0000179>sdc</obo:BFO_0000179>
        <obo:BFO_0000180>SpecificallyDependentContinuant</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">of one-sided specifically dependent continuants: the mass of this tomato</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the disposition of this fish to decay</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the function of this heart: to pump blood</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the mutual dependence of proton donors and acceptors in chemical reactions [79</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the pink color of a medium rare piece of grilled filet mignon at its center</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the role of being a doctor</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the shape of this hole.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the smell of this portion of mozzarella</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">b is a specifically dependent continuant = Def. b is a continuant &amp; there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Specifically dependent continuant doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. We&apos;re not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.</obo:IAO_0000116>
        <obo:IAO_0000602>(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] </obo:IAO_0000602>
        <rdfs:comment xml:lang="en">A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.</rdfs:comment>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">specifically dependent continuant</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
        <owl:annotatedTarget xml:lang="en">b is a specifically dependent continuant = Def. b is a continuant &amp; there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/050-003"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget xml:lang="en">Specifically dependent continuant doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. We&apos;re not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000005"/>
        <rdfs:comment>per discussion with Barry Smith</rdfs:comment>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/050-003"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000023 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000023">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000023</metadata:prefixIRI>
        <obo:BFO_0000179>role</obo:BFO_0000179>
        <obo:BFO_0000180>Role</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the priest role</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the role of a boundary to demarcate two neighboring administrative territories</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the role of a building in serving as a military target</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the role of a stone in marking a property boundary</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the role of subject in a clinical trial</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the student role</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role &amp; c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals –  professor, sergeant, nurse – only during certain phases in their lives.</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">b is a role means: b is a realizable entity &amp; b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be&amp; b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">role</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">b is a role means: b is a realizable entity &amp; b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be&amp; b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/061-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/061-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000024">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000024</metadata:prefixIRI>
        <obo:BFO_0000179>fiat-object-part</obo:BFO_0000179>
        <obo:BFO_0000180>FiatObjectPart</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the FMA:regional parts of an intact human body.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the Western hemisphere of the Earth</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the division of the brain into regions</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the division of the planet into hemispheres</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the dorsal and ventral surfaces of the body</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the upper and lower lobes of the left lung</obo:IAO_0000112>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of  c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">fiat object part</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000024"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of  c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/027-004"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000024"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/027-004"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000026</metadata:prefixIRI>
        <obo:BFO_0000179>1d-s-region</obo:BFO_0000179>
        <obo:BFO_0000180>OneDimensionalSpatialRegion</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">an edge of a cube-shaped portion of space.</obo:IAO_0000112>
        <obo:IAO_0000600 xml:lang="en">A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">one-dimensional spatial region</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000026"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/038-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000026"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/038-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000027</metadata:prefixIRI>
        <obo:BFO_0000179>object-aggregate</obo:BFO_0000179>
        <obo:BFO_0000180>ObjectAggregate</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">a collection of cells in a blood biobank.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a swarm of bees is an aggregate of members who are linked together through natural bonds</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a symphony orchestra</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">defined by fiat: the aggregate of members of an organization</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">defined through physical attachment: the aggregate of atoms in a lump of granite</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">defined via attributive delimitations such as: the patients in this hospital</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the aggregate of bearings in a constant velocity axle joint</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the aggregate of blood cells in your body</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the nitrogen atoms in the atmosphere</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the restaurants in Palo Alto</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">your collection of Meissen ceramic plates.</obo:IAO_0000112>
        <obo:IAO_0000116>An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects </obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee).</obo:IAO_0000116>
        <obo:IAO_0000119>ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, &apos;A Theory of Granular Partitions&apos;, in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.</obo:IAO_0000119>
        <obo:IAO_0000600 xml:lang="en">b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">object aggregate</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget>An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000011"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget>An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000301"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000119"/>
        <owl:annotatedTarget>ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, &apos;A Theory of Granular Partitions&apos;, in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000300"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/025-004"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000027"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/025-004"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000028">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000006"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000028</metadata:prefixIRI>
        <obo:BFO_0000179>3d-s-region</obo:BFO_0000179>
        <obo:BFO_0000180>ThreeDimensionalSpatialRegion</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">a cube-shaped region of space</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a sphere-shaped region of space,</obo:IAO_0000112>
        <obo:IAO_0000600 xml:lang="en">A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">three-dimensional spatial region</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/040-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000028"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/040-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000029</metadata:prefixIRI>
        <obo:BFO_0000179>site</obo:BFO_0000179>
        <obo:BFO_0000180>Site</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">Manhattan Canyon)</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a hole in the interior of a portion of cheese</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a rabbit hole</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">an air traffic control region defined in the airspace above an airport</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the Grand Canyon</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the Piazza San Marco</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the cockpit of an aircraft</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the hold of a ship</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the interior of a kangaroo pouch</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the interior of the trunk of your car</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the interior of your bedroom</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the interior of your office</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the interior of your refrigerator</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the lumen of your gut</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">your left nostril (a fiat part – the opening – of your left nasal cavity)</obo:IAO_0000112>
        <obo:IAO_0000600 xml:lang="en">b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">site</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/034-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/034-002"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000030">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000030</metadata:prefixIRI>
        <obo:BFO_0000179>object</obo:BFO_0000179>
        <obo:BFO_0000180>Object</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">atom</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">cell</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">cells and organisms</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">engineered artifacts</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">grain of sand</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">molecule</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">organelle</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">organism</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">planet</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">solid portions of matter</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">star</obo:IAO_0000112>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below).</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: an object is a maximal causally unified material entity</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above &amp; is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])</obo:IAO_0000600>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">object</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000030"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above &amp; is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/024-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000031">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000031</metadata:prefixIRI>
        <obo:BFO_0000179>gdc</obo:BFO_0000179>
        <obo:BFO_0000180>GenericallyDependentContinuant</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the pdf file on your laptop, the pdf file that is a copy thereof on my laptop</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])</obo:IAO_0000115>
        <obo:IAO_0000602>(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] </obo:IAO_0000602>
        <rdfs:comment xml:lang="en">A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.</rdfs:comment>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">generically dependent continuant</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
        <owl:annotatedTarget xml:lang="en">b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/074-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/074-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000034</metadata:prefixIRI>
        <obo:BFO_0000179>function</obo:BFO_0000179>
        <obo:BFO_0000180>Function</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">the function of a hammer to drive in nails</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the function of a heart pacemaker to regulate the beating of a heart through electricity</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the function of amylase in saliva to break down starch into sugar</obo:IAO_0000112>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc.</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">function</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/064-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/064-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000035">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000035</metadata:prefixIRI>
        <obo:BFO_0000179>p-boundary</obo:BFO_0000179>
        <obo:BFO_0000180>ProcessBoundary</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">the boundary between the 2nd and 3rd year of your life.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">p is a process boundary =Def. p is a temporal part of a process &amp; p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])</obo:IAO_0000115>
        <obo:IAO_0000601 xml:lang="en">Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">process boundary</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
        <owl:annotatedTarget xml:lang="en">p is a process boundary =Def. p is a temporal part of a process &amp; p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/084-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/085-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/085-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000035"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/084-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000038">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000148"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000038</metadata:prefixIRI>
        <obo:BFO_0000179>1d-t-region</obo:BFO_0000179>
        <obo:BFO_0000180>OneDimensionalTemporalRegion</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">the temporal region during which a process occurs.</obo:IAO_0000112>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks).</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">one-dimensional temporal region</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/103-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/103-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000040</metadata:prefixIRI>
        <obo:BFO_0000179>material</obo:BFO_0000179>
        <obo:BFO_0000180>MaterialEntity</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">a flame</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a forest fire</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a human being</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a hurricane</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a photon</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a puff of smoke</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a sea wave</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a tornado</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">an aggregate of human beings.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">an energy wave</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">an epidemic</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the undetached arm of a human being</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])</obo:IAO_0000600>
        <obo:IAO_0000601 xml:lang="en">Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])</obo:IAO_0000601>
        <obo:IAO_0000601 xml:lang="en">every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])</obo:IAO_0000601>
        <obo:IAO_0000602>(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] </obo:IAO_0000602>
        <obo:IAO_0000602>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">material entity</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/019-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/020-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000601"/>
        <owl:annotatedTarget xml:lang="en">every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/021-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/019-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/021-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/020-002"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000140 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000140">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000140</metadata:prefixIRI>
        <obo:BFO_0000179>cf-boundary</obo:BFO_0000179>
        <obo:BFO_0000180>ContinuantFiatBoundary</obo:BFO_0000180>
        <obo:IAO_0000115 xml:lang="en">b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Continuant fiat boundary doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn&apos;t overlap it. The situation is analogous to temporal and spatial regions.</obo:IAO_0000116>
        <obo:IAO_0000601 xml:lang="en">Every continuant fiat boundary is located at some spatial region at every time at which it exists</obo:IAO_0000601>
        <obo:IAO_0000602>(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">continuant fiat boundary</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
        <owl:annotatedTarget xml:lang="en">b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/029-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget xml:lang="en">Continuant fiat boundary doesn&apos;t have a closure axiom because the subclasses don&apos;t necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn&apos;t overlap it. The situation is analogous to temporal and spatial regions.</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000008"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/029-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000141 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000141">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000141</metadata:prefixIRI>
        <obo:BFO_0000179>immaterial</obo:BFO_0000179>
        <obo:BFO_0000180>ImmaterialEntity</obo:BFO_0000180>
        <obo:IAO_0000116 xml:lang="en">BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10</obo:IAO_0000116>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">immaterial entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000142 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000142">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000146"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000142</metadata:prefixIRI>
        <obo:BFO_0000179>1d-cf-boundary</obo:BFO_0000179>
        <obo:BFO_0000180>OneDimensionalContinuantFiatBoundary</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">The Equator</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">all geopolitical boundaries</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">all lines of latitude and longitude</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the median sulcus of your tongue</obo:IAO_0000112>
        <obo:IAO_0000600 xml:lang="en">a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">one-dimensional continuant fiat boundary</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000142"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/032-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000142"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/032-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000144 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000144">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/BFO_0000182"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000144</metadata:prefixIRI>
        <obo:BFO_0000179>process-profile</obo:BFO_0000179>
        <obo:BFO_0000180>ProcessProfile</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from   rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])</obo:IAO_0000115>
        <obo:IAO_0000600 xml:lang="en">b process_profile_of c holds when b proper_occurrent_part_of c&amp; there is some proper_occurrent_part d of c which has no parts in common with b &amp; is mutually dependent on b&amp; is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] </obo:IAO_0000602>
        <obo:IAO_0000602>(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">process profile</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
        <owl:annotatedTarget xml:lang="en">b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/093-002"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">b process_profile_of c holds when b proper_occurrent_part_of c&amp; there is some proper_occurrent_part d of c which has no parts in common with b &amp; is mutually dependent on b&amp; is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/094-005"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/094-005"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/093-002"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000145 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000145">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000145</metadata:prefixIRI>
        <obo:BFO_0000179>r-quality</obo:BFO_0000179>
        <obo:BFO_0000180>RelationalQuality</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">a marriage bond, an instance of requited love, an obligation between one person and another.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t &amp; b quality_of d at t. (axiom label in BFO2 Reference: [057-001])</obo:IAO_0000115>
        <obo:IAO_0000602>(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">relational quality</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000145"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
        <owl:annotatedTarget xml:lang="en">b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t &amp; b quality_of d at t. (axiom label in BFO2 Reference: [057-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/057-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000145"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/057-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000146</metadata:prefixIRI>
        <obo:BFO_0000179>2d-cf-boundary</obo:BFO_0000179>
        <obo:BFO_0000180>TwoDimensionalContinuantFiatBoundary</obo:BFO_0000180>
        <obo:IAO_0000600 xml:lang="en">a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">two-dimensional continuant fiat boundary</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000146"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/033-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000146"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/033-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000147 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000147">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000140"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000147</metadata:prefixIRI>
        <obo:BFO_0000179>0d-cf-boundary</obo:BFO_0000179>
        <obo:BFO_0000180>ZeroDimensionalContinuantFiatBoundary</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">the geographic North Pole</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the point of origin of some spatial coordinate system.</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet</obo:IAO_0000112>
        <obo:IAO_0000116 xml:lang="en">zero dimension continuant fiat boundaries are not spatial points. Considering the example &apos;the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet&apos; : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.</obo:IAO_0000116>
        <obo:IAO_0000600 xml:lang="en">a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">zero-dimensional continuant fiat boundary</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000116"/>
        <owl:annotatedTarget xml:lang="en">zero dimension continuant fiat boundaries are not spatial points. Considering the example &apos;the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet&apos; : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/0000001"/>
        <rdfs:comment>requested by Melanie Courtot</rdfs:comment>
        <rdfs:seeAlso rdf:resource="https://groups.google.com/d/msg/bfo-owl-devel/s9Uug5QmAws/ZDRnpiIi_TUJ"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/031-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000147"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/031-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000148 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000148">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000148</metadata:prefixIRI>
        <obo:BFO_0000179>0d-t-region</obo:BFO_0000179>
        <obo:BFO_0000180>ZeroDimensionalTemporalRegion</obo:BFO_0000180>
        <obo:IAO_0000112 xml:lang="en">a temporal region that is occupied by a process boundary</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">right now</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the moment at which a child is born</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the moment at which a finger is detached in an industrial accident</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">the moment of death.</obo:IAO_0000112>
        <obo:IAO_0000118 xml:lang="en">temporal instant.</obo:IAO_0000118>
        <obo:IAO_0000600 xml:lang="en">A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])</obo:IAO_0000600>
        <obo:IAO_0000602>(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] </obo:IAO_0000602>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">zero-dimensional temporal region</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000148"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/102-001"/>
    </owl:Axiom>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000148"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000602"/>
        <owl:annotatedTarget>(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] </owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/102-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BFO:0000182</metadata:prefixIRI>
        <obo:BFO_0000179>history</obo:BFO_0000179>
        <obo:BFO_0000180>History</obo:BFO_0000180>
        <obo:IAO_0000600 xml:lang="en">A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])</obo:IAO_0000600>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">history</rdfs:label>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/BFO_0000182"/>
        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000600"/>
        <owl:annotatedTarget xml:lang="en">A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])</owl:annotatedTarget>
        <obo:IAO_0010000 rdf:resource="http://purl.obolibrary.org/obo/bfo/axiom/138-001"/>
    </owl:Axiom>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_15882 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_15882">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C6H6O</chebi:formula>
        <chebi:inchi>InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H</chebi:inchi>
        <chebi:inchikey>ISWSIDIOOBJBQZ-UHFFFAOYSA-N</chebi:inchikey>
        <chebi:mass>94.11120</chebi:mass>
        <chebi:monoisotopicmass>94.04186</chebi:monoisotopicmass>
        <chebi:smiles>Oc1ccccc1</chebi:smiles>
        <oboInOwl:hasAlternativeId>CHEBI:14777</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:25966</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:43543</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:8071</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:108-95-2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB03255</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Drug_Central:4266</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:2794</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0000228</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00146</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C15584</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00033</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D06536</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KNApSAcK:C00002664</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:IPH</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12058733</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16953321</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17852157</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19029204</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:20886261</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21492257</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21689881</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21809019</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21822930</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:969616</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UM-BBD_compID:c0128</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Phenol</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>PHENOL</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Phenol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>phenol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Benzenol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Carbolsaeure</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Hydroxybenzene</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Karbolsaeure</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Oxybenzene</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>PhOH</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Phenic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Phenylic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Phenylic alcohol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>acide carbolique</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>acide phenique</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>carbolic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:15882</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>phenol</rdfs:label>
        <skos:notation>CHEBI:15882</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_16199 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16199">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O).</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>CH4N2O</chebi:formula>
        <chebi:inchi>InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)</chebi:inchi>
        <chebi:inchikey>XSQUKJJJFZCRTK-UHFFFAOYSA-N</chebi:inchikey>
        <chebi:mass>60.05534</chebi:mass>
        <chebi:monoisotopicmass>60.03236</chebi:monoisotopicmass>
        <chebi:smiles>NC(N)=O</chebi:smiles>
        <oboInOwl:hasAlternativeId>CHEBI:15292</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:27218</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:46379</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:9888</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:57-13-6</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB03904</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Drug_Central:4264</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ECMDB:ECMDB04172</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:1378</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0000294</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00086</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00023</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KNApSAcK:C00007314</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:UREA</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:URE</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18037357</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22770225</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PPDB:1728</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:635724</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UM-BBD_compID:c0165</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Urea</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>YMDB:YMDB00003</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>UREA</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Urea</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>urea</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>1728</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Carbamide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>E927b</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>H2NC(O)NH2</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Harnstoff</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Karbamid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>carbamide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>carbonyldiamide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>ur</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>uree</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:16199</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>urea</rdfs:label>
        <skos:notation>CHEBI:16199</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_16412 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16412">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <oboInOwl:hasAlternativeId>CHEBI:14520</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:25062</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:6494</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>KEGG:C00338</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15589368</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24186868</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24506665</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24642373</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24659348</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Lipopolysaccharide</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>LPS</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>lipopolysaccharides</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:16412</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>lipopolysaccharide</rdfs:label>
        <skos:notation>CHEBI:16412</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_16670 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16670">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>(C2H2NOR)nC2H3NOR</chebi:formula>
        <oboInOwl:hasAlternativeId>CHEBI:14753</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:25906</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:7990</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>KEGG:C00012</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Peptide</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>peptides</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Peptid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>peptido</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>peptidos</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:16670</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>peptide</rdfs:label>
        <skos:notation>CHEBI:16670</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_16842 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16842">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>An aldehyde resulting from the formal oxidation of methanol.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>CH2O</chebi:formula>
        <chebi:inchi>InChI=1S/CH2O/c1-2/h1H2</chebi:inchi>
        <chebi:inchikey>WSFSSNUMVMOOMR-UHFFFAOYSA-N</chebi:inchikey>
        <chebi:mass>30.02598</chebi:mass>
        <chebi:monoisotopicmass>30.01056</chebi:monoisotopicmass>
        <chebi:smiles>[H]C([H])=O</chebi:smiles>
        <oboInOwl:hasAlternativeId>CHEBI:14274</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:24077</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:337763</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:5142</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:50-00-0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB03843</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Drug_Central:3244</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:445</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0001426</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00067</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00017</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:FORMALDEHYDE</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:FOR</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:110589</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12686735</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15091529</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16423181</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17618393</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18837732</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25042713</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7381846</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7548723</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7689168</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7896413</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9686972</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PPDB:359</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:1209228</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UM-BBD_compID:c0122</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Formaldehyde</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>FORMALDEHYDE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Formaldehyde</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>formaldehyde</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>FORMALIN</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Formaldehyd</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Formalin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Methanal</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Methylene oxide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Oxomethane</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Oxomethylene</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:16842</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>formaldehyde</rdfs:label>
        <skos:notation>CHEBI:16842</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_17076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C21H39N7O12</chebi:formula>
        <chebi:inchi>InChI=1S/C21H39N7O12/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+/m0/s1</chebi:inchi>
        <chebi:inchikey>UCSJYZPVAKXKNQ-HZYVHMACSA-N</chebi:inchikey>
        <chebi:mass>581.57434</chebi:mass>
        <chebi:monoisotopicmass>581.26567</chebi:monoisotopicmass>
        <chebi:smiles>CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@@H](O[C@@H](C)[C@]1(O)C=O)O[C@H]1[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]1NC(N)=N</chebi:smiles>
        <oboInOwl:hasAlternativeId>CHEBI:15119</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:26784</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:45745</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:9284</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:57-92-1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB01082</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Drug_Central:2481</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0015214</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00413</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D08531</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:STREPTOMYCIN</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:SRY</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11228320</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11905029</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12118520</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13030054</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13116094</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13136149</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13596285</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13691614</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13985260</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13990247</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:14623118</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:14828344</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:14852338</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:14939639</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15081082</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15137533</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15207172</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15686853</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15736038</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16904706</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17105735</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17238915</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17429930</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18173084</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18916143</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19052412</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19335957</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21350946</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21362244</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21593257</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21937264</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22101040</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Pesticides:streptomycin</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:74498</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Streptomycin</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>N,N&apos;&apos;&apos;-[(1R,2R,3S,4R,5R,6S)-4-{5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>STREPTOMYCIN</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Kantrex</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>SM</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>[2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1-&gt;2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1-&gt;4)-{N&apos;,N&apos;&apos;&apos;-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>streomycin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>streptomycin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:17076</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>streptomycin</rdfs:label>
        <skos:notation>CHEBI:17076</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_17716 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17716">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>A glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-1-&gt;4 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C12H22O11</chebi:formula>
        <chebi:inchi>InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11?,12+/m1/s1</chebi:inchi>
        <chebi:inchikey>GUBGYTABKSRVRQ-QKKXKWKRSA-N</chebi:inchikey>
        <chebi:mass>342.297</chebi:mass>
        <chebi:monoisotopicmass>342.11621</chebi:monoisotopicmass>
        <chebi:smiles>OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O</chebi:smiles>
        <oboInOwl:hasAlternativeId>CHEBI:10296</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:10380</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:14497</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:22460</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:22760</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:25005</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:27755</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:613009</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:63-42-3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GlyGen:G74621DY</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GlyTouCan:G74621DY</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:882872</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00243</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00046</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:G10504</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KNApSAcK:C00001136</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1292745</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17329833</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18300214</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19053747</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19846069</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19913595</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:20094999</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:20503067</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:20699559</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:20873837</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:20961532</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21403918</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2432147</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2456994</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:28690131</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:28807538</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:6194884</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7574700</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:1292745</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>beta-D-galactopyranosyl-(1-&gt;4)-D-glucopyranose</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>lactose</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>(+)-lactose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(Gal)1 (Glc)1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>1-beta-D-Galactopyranosyl-4-D-glucopyranose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>4-(beta-D-galactosido)-D-glucose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>4-O-beta-D-galactopyranosyl-D-glucose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>D-lactose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Galbeta1-4Glc</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Lac</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Laktobiose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Laktose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Milchzucker</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Milk sugar</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>WURCS=2.0/2,2,1/[a2122h-1x_1-5][a2112h-1b_1-5]/1-2/a4-b1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>beta-D-Gal-(1-&gt;4)-D-Glc</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>beta-D-Galp-(1-&gt;4)-D-Glcp</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>beta-Gal1,4-Glc</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>lactobiose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>milk sugar</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:17716</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>lactose</rdfs:label>
        <skos:notation>CHEBI:17716</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_17833 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17833">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <oboInOwl:hasAlternativeId>CHEBI:14293</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:24206</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:24212</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:5306</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:1403-66-3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB00798</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00505</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Gentamicin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gentamycins</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:17833</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>gentamycin</rdfs:label>
        <skos:notation>CHEBI:17833</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_17992 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17992">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>A glycosyl glycoside formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C12H22O11</chebi:formula>
        <chebi:inchi>InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1</chebi:inchi>
        <chebi:inchikey>CZMRCDWAGMRECN-UGDNZRGBSA-N</chebi:inchikey>
        <chebi:mass>342.29650</chebi:mass>
        <chebi:monoisotopicmass>342.11621</chebi:monoisotopicmass>
        <chebi:smiles>OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O</chebi:smiles>
        <oboInOwl:hasAlternativeId>CHEBI:15128</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:26812</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:45795</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:9314</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:57-50-1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB02772</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Drug_Central:4610</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:97695</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0000258</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00089</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00025</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D06533</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:G00370</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KNApSAcK:C00001151</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:SUCROSE</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:SUC</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11021636</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11093712</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11111003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12065720</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12706980</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13508893</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15291457</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15660210</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15792978</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15845855</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16228482</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16304615</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16313996</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16525719</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16660545</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16663947</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16665852</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17233733</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17439666</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17597061</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18625236</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19199566</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19726178</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21703290</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21972845</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22085755</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22311778</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22404833</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22751876</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:1435311</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:90825</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Sucrose</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>SUCROSE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Sucrose</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>beta-D-fructofuranosyl alpha-D-glucopyranoside</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>sucrose</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranoside</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Cane sugar</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Saccharose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Sacharose</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>White sugar</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>beta-D-Fruf-(2&lt;-&gt;1)-alpha-D-Glcp</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>sacarosa</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>table sugar</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:17992</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>sucrose</rdfs:label>
        <skos:notation>CHEBI:17992</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_23367 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23367">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24431"/>
        <obo:IAO_0000115>Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <oboInOwl:hasExactSynonym>molecular entity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>entidad molecular</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>entidades moleculares</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>entite moleculaire</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>molecular entities</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>molekulare Entitaet</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:23367</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>molecular entity</rdfs:label>
        <skos:notation>CHEBI:23367</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_24431 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24431">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <obo:IAO_0000115>A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <oboInOwl:hasExactSynonym>chemical entity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>CHEBI:24431</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>chemical entity</rdfs:label>
        <skos:notation>CHEBI:24431</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_26710 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_26710">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>An inorganic chloride salt having sodium(1+) as the counterion.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>ClNa</chebi:formula>
        <chebi:inchi>InChI=1S/ClH.Na/h1H;/q;+1/p-1</chebi:inchi>
        <chebi:inchikey>FAPWRFPIFSIZLT-UHFFFAOYSA-M</chebi:inchikey>
        <chebi:mass>58.44247</chebi:mass>
        <chebi:monoisotopicmass>57.95862</chebi:monoisotopicmass>
        <chebi:smiles>[Na+].[Cl-]</chebi:smiles>
        <oboInOwl:hasDbXref>CAS:7647-14-5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:13673</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C13563</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D02056</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:NACL</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PPDB:595</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:3534976</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Sodium_Chloride</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>sodium chloride</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Kochsalz</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>NaCl</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Natriumchlorid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>chlorure de sodium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>cloruro sodico</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>common salt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>halite</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>natrii chloridum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>rock salt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>salt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>table salt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:26710</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>sodium chloride</rdfs:label>
        <skos:notation>CHEBI:26710</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_2877 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_2877">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16670"/>
        <obo:IAO_0000115>A dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C14H18N2O5</chebi:formula>
        <chebi:inchi>InChI=1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1</chebi:inchi>
        <chebi:inchikey>IAOZJIPTCAWIRG-QWRGUYRKSA-N</chebi:inchikey>
        <chebi:mass>294.304</chebi:mass>
        <chebi:monoisotopicmass>294.12157</chebi:monoisotopicmass>
        <chebi:smiles>C(C[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(=O)OC)=O)N)(=O)O</chebi:smiles>
        <oboInOwl:hasAlternativeId>CHEBI:45047</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:22839-47-0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB00168</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0001894</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C11045</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D02381</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:PME</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1771173</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2013754</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>PMID:24925367</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>PMID:26912665</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27015640</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27038223</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27088715</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27127997</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27216413</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27298583</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27492574</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27565676</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27614095</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27640132</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27699780</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27728881</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27840415</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27845306</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:30000570</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:37291632</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:37297402</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:37454665</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Patent:US3492131</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:2223850</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Aspartame</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Aspartame</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>methyl L-alpha-aspartyl-L-phenylalaninate</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>1-methyl N-L-alpha-aspartyl-L-phenylalanate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>AminoSweet</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Asp-phe-ome</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Aspartylphenylalanine methyl ester</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>E 951</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>L-Aspartyl-L-phenylalanine methyl ester</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>NutraSweet</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Sanecta</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>aspartam</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>aspartamo</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>aspartamum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:2877</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>aspartame</rdfs:label>
        <skos:notation>CHEBI:2877</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_30911 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_30911">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C6H14O6</chebi:formula>
        <chebi:mass>182.172</chebi:mass>
        <chebi:monoisotopicmass>182.07904</chebi:monoisotopicmass>
        <oboInOwl:hasAlternativeId>CHEBI:15093</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:26724</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:26726</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:33795</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:33796</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:9201</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>Beilstein:1721909</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:83165</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Sorbitol</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>glucitol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Sorbitol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gulitol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>rel-(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:30911</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>glucitol</rdfs:label>
        <skos:notation>CHEBI:30911</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_32111 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_32111">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C7H5NO3S</chebi:formula>
        <chebi:inchi>InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)</chebi:inchi>
        <chebi:inchikey>CVHZOJJKTDOEJC-UHFFFAOYSA-N</chebi:inchikey>
        <chebi:mass>183.18500</chebi:mass>
        <chebi:monoisotopicmass>182.99901</chebi:monoisotopicmass>
        <chebi:smiles>O=C1NS(=O)(=O)c2ccccc12</chebi:smiles>
        <oboInOwl:hasAlternativeId>CHEBI:49717</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:81-07-2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:4203</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0029723</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D01085</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:CPD-5581</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:LSA</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24456165</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24549104</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24739358</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24780866</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:6888</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Saccharin</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>1,2-benzisothiazol-3(2H)-one 1,1-dioxide</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Saccharin</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>1,1-Dioxo-1,2-benzisothiazol-3(2H)-one</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>1,1-Dioxo-1,2-dihydro-benzo[d]isothiazol-3-one</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>1,2-Benzisothiazol-3(2H)-one 1,1-dioxide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>1,2-Benzisothiazolin-3-one 1,1-dioxide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>1,2-Dihydro-2-ketobenzisosulfonazole</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>1,2-Dihydro-2-ketobenzisosulphonazole</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>2,3-Dihydro-3-oxobenzisosulfonazole</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>2,3-Dihydro-3-oxobenzisosulphonazole</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>3-Hydroxybenzisothiazole-S,S-dioxide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Anhydro-o-sulfaminebenzoic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Benzo-2-sulphimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Benzoic acid sulfimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Benzoic sulfimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Benzoic sulphimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Benzosulfimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Benzosulphimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Benzoylsulfonic Imide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Saccharimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Saccharine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>o-Benzoic sulfimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>o-Benzosulfimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>o-Sulfobenzimide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>o-Sulfobenzoic acid imide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:32111</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>saccharin</rdfs:label>
        <skos:notation>CHEBI:32111</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_33130 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33130">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>AlH3O3</chebi:formula>
        <chebi:formula>H3AlO3</chebi:formula>
        <chebi:inchi>InChI=1S/Al.3H2O/h;3*1H2/q+3;;;/p-3</chebi:inchi>
        <chebi:inchikey>WNROFYMDJYEPJX-UHFFFAOYSA-K</chebi:inchikey>
        <chebi:mass>78.00356</chebi:mass>
        <chebi:monoisotopicmass>77.98976</chebi:monoisotopicmass>
        <chebi:smiles>[H]O[Al](O[H])O[H]</chebi:smiles>
        <oboInOwl:hasAlternativeId>CHEBI:30193</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:31195</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:21645-51-2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Drug_Central:4250</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:22216</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C13391</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D02859</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Aluminum_Hydroxide</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>aluminium(3+) hydroxide</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>aluminium(III) hydroxide</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>trihydroxidoaluminium</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Al(OH)3</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Aluminiumhydroxid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Aluminum hydroxide</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:33130</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>aluminium hydroxide</rdfs:label>
        <skos:notation>CHEBI:33130</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_37586 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_37586">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <oboInOwl:hasDbXref>CAS:7632-05-5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Sodium_phosphates</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>sodium phosphate</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>phosphoric acid, sodium salt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>sodium orthophosphate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>sodium phosphates</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>sodium salt of phosphoric acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:37586</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>sodium phosphate</rdfs:label>
        <skos:notation>CHEBI:37586</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_52071 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_52071">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>A (1-&gt;6)-alpha-D-glucan which has extra branching consisting of (1-&gt;2), (1-&gt;3) or (1-&gt;4) linkages.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <oboInOwl:hasDbXref>CAS:9004-54-0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00372</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00060</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D06541</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:G10502</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8154046</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>(1,6-alpha-D-Glucosyl)m</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(1,6-alpha-D-Glucosyl)m+1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(1,6-alpha-D-Glucosyl)n</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(1,6-alpha-D-Glucosyl)n+1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>1,6-alpha-D-Glucan</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Dextran 40</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Dextran 70</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Dextran 75</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>dextran</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>dextrane</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>dextrano</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>dextrans</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>dextranum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:52071</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>dextran</rdfs:label>
        <skos:notation>CHEBI:52071</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_53424 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_53424">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C58H114O26</chebi:formula>
        <chebi:mass>1226.75977</chebi:mass>
        <chebi:monoisotopicmass>1226.760</chebi:monoisotopicmass>
        <oboInOwl:hasDbXref>CAS:9005-64-5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C11624</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D05565</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:8187252</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:8973037</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Polysorbate_20</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Polyoxyethylene (20) sorbitan monolaurate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Polyoxyethylene sorbitan monolaurate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Polysorbate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Polysorbate 20</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Tween 20</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>polisorbato</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>polysorbate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>polysorbatum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:53424</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>polysorbate 20</rdfs:label>
        <skos:notation>CHEBI:53424</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_53426 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_53426">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by an oleoyl group.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C64H124O26</chebi:formula>
        <chebi:mass>1308.83802</chebi:mass>
        <chebi:monoisotopicmass>1308.838</chebi:monoisotopicmass>
        <oboInOwl:hasAlternativeId>CHEBI:9785</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>CAS:9005-65-6</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C11625</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D01067</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:8187125</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:8190601</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:8898414</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:9040798</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Polysorbate_80</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Glycol (polysorbate 80)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Polyethylene oxide sorbitan mono-oleate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Polyoxyethylene (20) sorbitan monooleate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Polyoxyethylene sorbitan monooleate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Polyoxyethylene sorbitan oleate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Polysorbate 80</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Tween 80</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>polisorbato</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>polysorbate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>polysorbatum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:53426</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>polysorbate 80</rdfs:label>
        <skos:notation>CHEBI:53426</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_64220 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_64220">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>An organic sodium salt that is the monosodium salt of glutamic acid.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C5H8NNaO4</chebi:formula>
        <chebi:inchi>InChI=1S/C5H9NO4.Na/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);/q;+1/p-1</chebi:inchi>
        <chebi:inchikey>LPUQAYUQRXPFSQ-UHFFFAOYSA-M</chebi:inchikey>
        <chebi:mass>169.11110</chebi:mass>
        <chebi:monoisotopicmass>169.03510</chebi:monoisotopicmass>
        <chebi:smiles>[Na+].[NH3+]C(CCC([O-])=O)C([O-])=O</chebi:smiles>
        <oboInOwl:hasDbXref>PMID:22293291</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:17003240</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>sodium 2-azaniumylpentanedioate</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>MSG</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>sodium 2-ammoniopentanedioate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>sodium glutamate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:64220</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>monosodium glutamate</rdfs:label>
        <skos:notation>CHEBI:64220</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_7507 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_7507">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <oboInOwl:hasDbXref>CAS:1404-04-2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB00994</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00384</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D08260</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Neomycin</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>CHEBI:7507</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>neomycin</rdfs:label>
        <skos:notation>CHEBI:7507</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_9546 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_9546">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
        <chebi:charge>0</chebi:charge>
        <chebi:formula>C9H9HgNaO2S</chebi:formula>
        <chebi:formula>C9H9HgO2S.Na</chebi:formula>
        <chebi:inchi>InChI=1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2</chebi:inchi>
        <chebi:inchikey>RTKIYNMVFMVABJ-UHFFFAOYSA-L</chebi:inchikey>
        <chebi:mass>404.81233</chebi:mass>
        <chebi:monoisotopicmass>405.99274</chebi:monoisotopicmass>
        <chebi:smiles>[Na+].CC[Hg]Sc1ccccc1C([O-])=O</chebi:smiles>
        <oboInOwl:hasDbXref>CAS:54-64-8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Gmelin:1677155</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00864</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18837732</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21616561</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21785120</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22015977</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22366633</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22658806</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22811707</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23145070</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23223227</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23282150</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23401210</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23554557</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23843785</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23949514</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23965928</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23992327</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25042713</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PPDB:3062</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:8169555</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VSDB:3062</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Thimerosal</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>sodium [(2-carboxylatophenyl)sulfanyl](ethyl)mercurate(1-)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>sodium ethyl[2-(sulfanyl-kappaS)benzoato(2-)]mercurate(1-)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Merthiolate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Thiomersal</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>[(o-carboxyphenyl)thio]ethylmercury sodium salt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>ethyl(2-mercaptobenzoato-S)mercury sodium salt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>ethylmercurithiosalicylate sodium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>ethylmercurithiosalicylic acid sodium salt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>mercurothiolate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>o-(ethylmercurithio)benzoic acid sodium salt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>sodium ethylmercurithiosalicylate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>sodium merthiolate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>thiomersal</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>thiomersalate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>thiomersalum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>tiomersal</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:9546</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <rdfs:label>thimerosal</rdfs:label>
        <skos:notation>CHEBI:9546</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000061"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000000</metadata:prefixIRI>
        <obo:IAO_0000115>A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:hasDbXref>CALOHA:TS-2035</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:00007002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:68646</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GO:0005623</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KUPO:0000002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002477</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0001533</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>WBbt:0004017</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0003012</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0009000</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/ubprop#_upper_level"/>
        <rdfs:comment>The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one).</rdfs:comment>
        <rdfs:label>cell</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000113 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000113">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000518"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000842"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000113</metadata:prefixIRI>
        <obo:IAO_0000115>A vertebrate phagocyte with a single nucleus.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <terms:description>This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies to only to some subtypes and species, and so should not be considered definitional.

Mononuclear phagocytes are immune cells that form a critical part of the body&apos;s innate immune system, the body&apos;s first line of defense against infections. Mononuclear phagocytes are characterized by the presence of a single, large nucleus. The ‘Mononuclear Phagocyte System’ nomenclature was introduced to distinguish mononuclear monocytes and macrophages from other cells with multiple nuclei. However, the cells within the mononuclear phagocyte system represent a highly heterogeneous group, all of which are able to perform highly efficient phagocytosis - engulfing and digesting microbes and cellular debris to fight infections and to maintain normal tissue homeostasis. 
In addition to phagocytosis, mononuclear phagocytes also secrete chemical compounds to recruit other immune cells to a site of infection. These cells produce different types of signaling molecules, including cytokines, chemokines, and reactive oxygen species, triggering a cascade of responses to ensure rapid and efficient containment and neutralization of invading pathogens. These cells are also involved in antigen presentation, a process essential for stimulating an adaptive immune response. They can process and present antigens to T cells, thereby linking the innate and adaptive immune responses.
Mononuclear phagocytes play key roles in tissue repair and remodeling. After infection or injury, these cells help in the clearance of dead cells and debris, a crucial step in the initiation of tissue remodeling and the resolution of inflammation. Overall, mononuclear phagocytes are versatile cells that have tailored their functions to meet the unique challenges of different tissues within the body. They are pivotal in homeostasis, immunity, and inflammation, making them important aspects in a range of human diseases including infection, autoimmunity, and cancer.</terms:description>
        <oboInOwl:hasDbXref>BTO:0001433</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0009064</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>https://cellxgene.cziscience.com/cellguide/CL_0000113</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <rdfs:label>mononuclear phagocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000255"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000182</metadata:prefixIRI>
        <obo:IAO_0000115>The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <terms:description>This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies to only to some subtypes and species, and so should not be considered definitional.

Hepatocytes are the major cell type constituting 70-80% of the liver&apos;s cytoplasmic mass, playing crucial roles in maintaining the body&apos;s metabolic homeostasis. Dimensions of mature hepatocytes typically range from 20 to 30 μm in humans, but size may vary depending on their location within the liver lobule. Hepatocytes are characterized by high biosynthetic, enzymatic, and endocytic activity. They contain abundant mitochondria, smooth and rough endoplasmic reticulum, peroxisomes, lysosomes, and a large nucleus that is often binucleate. 
The liver consists of three zones - the periportal Zone 1, midzone 2, and pericentral Zone 3 - which have differential nutrient and oxygen status, and damage susceptibility; hepatocytes in the different zones show signifcant functional heterogeneity (&apos;hepatocyte functional zonation&apos;). Hepatocytes are involved in a multitude of critical functions including the metabolism of lipids, carbohydrates, and proteins, the synthesis of serum proteins (e.g., albumin, transferrin, and lipoproteins), the detoxification and excretion of endogenous and exogenous substances, the storage of vitamins and minerals, and the production and secretion of bile. 
Heterocytes demonstrate a remarkable regenerative capacity, which enables the liver to recover from injury and loss of tissue mass. Notably, hepatocytes perform biotransformation with both phase I and phase II enzymes, which modify drugs, xenobiotics, and various substances for elimination from the body. Phase I enzymes, such as cytochrome P450, catalyze both oxidative and reductive reactions of many xenobiotics; many of the products of phase I enzymes are substrates for the phase II enzymes, which catalyze conjugation reactions. 
Alterations in hepatocyte function have significant implications for overall human health and disease. Certain conditions, such as hepatitis, cirrhosis, and liver cancer, can profoundly affect hepatocyte structure and function, thereby disrupting the liver&apos;s ability to perform its vital roles within the body. As the primary site for drug metabolism, changes in hepatocyte function can also impact the effectiveness and toxicity of pharmaceuticals. The regenerative ability of hepatocytes makes them valuable cells for liver regenerative medicine and bioartificial liver support systems, and their study has provided significant insights into liver biology and disease.</terms:description>
        <oboInOwl:hasDbXref>BTO:0000575</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0454</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:14515</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0009111</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>https://cellxgene.cziscience.com/cellguide/CL_0000182</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <rdfs:comment>Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive.</rdfs:comment>
        <rdfs:label>hepatocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000219 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000219">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000219</metadata:prefixIRI>
        <obo:IAO_0000115>A cell that moves by its own activities.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:hasDbXref>ZFA:0009136</oboInOwl:hasDbXref>
        <rdfs:label>motile cell</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000226 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000226">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000255"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0002242"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000226</metadata:prefixIRI>
        <obo:IAO_0000115>A cell with a single nucleus.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <rdfs:label>single nucleate cell</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000232">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000763"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000232</metadata:prefixIRI>
        <obo:IAO_0000115>A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:hasDbXref>BTO:0000424</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0290</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:81100</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>RBC</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>red blood cell</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#blood_and_immune_upper_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <rdfs:label>erythrocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000234">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000219"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000234</metadata:prefixIRI>
        <obo:IAO_0000115>Any cell capable of ingesting particulate matter via phagocytosis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:hasDbXref>BTO:0001044</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:83806</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D010586</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0009140</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <rdfs:label>phagocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000235 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000235">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000113"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000766"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000235</metadata:prefixIRI>
        <obo:IAO_0000115>A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:hasDbXref>BTO:0000801</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0587</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:63261</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:83585</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008264</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0009141</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>histiocyte</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#blood_and_immune_upper_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#general_cell_types_upper_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <rdfs:comment>Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse &amp; Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, &amp; tissue remodelling; lineage: hematopoietic, myeloid.</rdfs:comment>
        <rdfs:label>macrophage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000255</metadata:prefixIRI>
        <obo:IAO_0000115>Any cell that in taxon some Eukaryota.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:hasDbXref>MESH:D005057</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <rdfs:label>eukaryotic cell</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000518 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000518">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000234"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000255"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000518</metadata:prefixIRI>
        <obo:IAO_0000115>A phagocyte in vertebrates that is able to phagocytosis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <rdfs:label>phagocyte (sensu Vertebrata)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000738 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000738">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000219"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000255"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000988"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0002242"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000738</metadata:prefixIRI>
        <obo:IAO_0000115>An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:hasDbXref>BTO:0000751</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0549</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:62852</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D007962</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12529</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0009309</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>leucocyte</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>white blood cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>immune cell</oboInOwl:hasRelatedSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <rdfs:label>leukocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000763 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000763">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000255"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000988"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000763</metadata:prefixIRI>
        <obo:IAO_0000115>A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:hasDbXref>BTO:0001441</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0647</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D022423</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0009324</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <rdfs:label>myeloid cell</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000766 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000766">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000738"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000763"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000766</metadata:prefixIRI>
        <obo:IAO_0000115>A cell of the monocyte, granulocyte, or mast cell lineage.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:hasDbXref>ZFA:0009326</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <rdfs:label>myeloid leukocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000842 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000842">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000226"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000738"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000842</metadata:prefixIRI>
        <obo:IAO_0000115>A leukocyte with a single non-segmented nucleus in the mature form.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:hasDbXref>BTO:0000878</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0768</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:86713</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0009357</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>mononuclear leukocyte</oboInOwl:hasExactSynonym>
        <oboInOwl:hasNarrowSynonym>peripheral blood mononuclear cell</oboInOwl:hasNarrowSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#blood_and_immune_upper_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <rdfs:label>mononuclear cell</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000988 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000988">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0000988</metadata:prefixIRI>
        <obo:IAO_0000115>A cell of a hematopoietic lineage.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:hasDbXref>BTO:0000574</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-2017</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:70366</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:83598</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0005830</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>haematopoietic cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>haemopoietic cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hemopoietic cell</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/cl#cellxgene_subset"/>
        <rdfs:label>hematopoietic cell</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0002242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0002242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CL:0002242</metadata:prefixIRI>
        <obo:IAO_0000115>A cell containing at least one nucleus.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0003-1980-3228"/>
        <oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2010-09-07T03:32:33Z</oboInOwl:creation_date>
        <oboInOwl:hasDbXref>FMA:67513</oboInOwl:hasDbXref>
        <rdfs:label>nucleate cell</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0040084 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0040084">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_874"/>
        <obo:IAO_0000115 xml:lang="en">A bacterial pneumonia has_material_basis_in Streptococcus pneumoniae.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:J13</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:481</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0040084</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_IEDB_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <rdfs:label xml:lang="en">Streptococcus pneumonia</rdfs:label>
        <skos:notation>DOID:0040084</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0050012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0050012">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in infection located_in joint, has_material_basis_in Chikungunya virus (Alphavirus chikungunya), which is transmitted_by Aedes mosquito bite. The infection has_symptom fever, has_symptom arthralgia, and has_symptom maculopapular rash.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:6038</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Chikungunya fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0050012</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">chikungunya</rdfs:label>
        <skos:notation>DOID:0050012</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0050117 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0050117">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4"/>
        <obo:IAO_0000115 xml:lang="en">A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <obo:OBI_9991118>infectious disease</obo:OBI_9991118>
        <oboInOwl:hasAlternativeId>DOID:10115</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:11078</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1304</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1321</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2040</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2288</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:3099</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4120</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4620</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:5256</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:945</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:95</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9532</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9696</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD9CM:079.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0001485</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">infectious disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0050117</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <rdfs:comment xml:lang="en">DO:wk</rdfs:comment>
        <rdfs:label xml:lang="en">disease by infectious agent</rdfs:label>
        <skos:notation>DOID:0050117</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0050175 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0050175">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in inflammation located_in brain, has_material_basis_in Tick-borne encephalitis virus (Orthoflavivirus encephalitidis), which is transmitted_by Ixodes ticks. The infection has_symptom drowsiness, has_symptom confusion, has_symptom sensory disturbances, and has_symptom paralysis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:0050176</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:10251</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:10252</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:5216</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A84.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:063.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D004675</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:16901001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0014054</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Central European encephalitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Far Eastern TBE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Russian spring-summer encephalitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Siberian tick-borne encephalitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Taiga encephalitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Western European tick-borne encephalitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">west-Siberian encephalitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0050175</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#tick-borne_infectious_disease"/>
        <rdfs:label xml:lang="en">tick-borne encephalitis</rdfs:label>
        <skos:notation>DOID:0050175</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0050338 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0050338">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_104"/>
        <obo:IAO_0000115 xml:lang="en">A bacterial infectious disease that results_in infection by bacteria as a result of their presence or activity within the normal, healthy host, and their intrinsic virulence is, in part, a necessary consequence of their need to reproduce and spread.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0050338</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <rdfs:label xml:lang="en">primary bacterial infectious disease</rdfs:label>
        <skos:notation>DOID:0050338</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0050615 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0050615">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_1579"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer located_in the respiratory system that is characterized by uncontrolled cellular proliferation in the respiratory tract.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0050615</oboInOwl:id>
        <rdfs:label xml:lang="en">respiratory system cancer</rdfs:label>
        <skos:notation>DOID:0050615</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0050686 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0050686">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:IAO_0000115 xml:lang="en">A cancer that is classified based on the organ it starts in.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:created_by>snadendla</oboInOwl:created_by>
        <oboInOwl:creation_date>2011-06-13T03:28:33Z</oboInOwl:creation_date>
        <oboInOwl:hasDbXref>MESH:D009371</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0050686</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <rdfs:label xml:lang="en">organ system cancer</rdfs:label>
        <skos:notation>DOID:0050686</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0050687 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0050687">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:IAO_0000115 xml:lang="en">A cancer that is classified by the type of cell from which it is derived.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:created_by>snadendla</oboInOwl:created_by>
        <oboInOwl:creation_date>2011-06-13T03:28:50Z</oboInOwl:creation_date>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0050687</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <rdfs:label xml:lang="en">cell type cancer</rdfs:label>
        <skos:notation>DOID:0050687</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0050746 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0050746">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_707"/>
        <obo:IAO_0000115 xml:lang="en">A B-cell lymphocytic neoplasm due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:created_by>lschriml</oboInOwl:created_by>
        <oboInOwl:creation_date>2012-09-18T02:00:45Z</oboInOwl:creation_date>
        <oboInOwl:hasDbXref>GARD:6969</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9673/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D020522</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0050746</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <rdfs:label xml:lang="en">mantle cell lymphoma</rdfs:label>
        <skos:notation>DOID:0050746</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0060058 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0060058">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0060073"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_2531"/>
        <obo:IAO_0000115 xml:lang="en">A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1033</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:353</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C85.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9590/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008223</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3208</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7065</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:118600007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:414628006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0024299</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0598798</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">lymphoid cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0060058</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">lymphoma</rdfs:label>
        <skos:notation>DOID:0060058</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0060073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0060073">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0060083"/>
        <obo:IAO_0000115 xml:lang="en">An immune system cancer that is located_in the lymphatic system and is characterized by uncontrolled cellular proliferation of lymphoid tissue.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:created_by>lschriml</oboInOwl:created_by>
        <oboInOwl:creation_date>2011-05-11T01:05:14Z</oboInOwl:creation_date>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0060073</oboInOwl:id>
        <rdfs:label xml:lang="en">lymphatic system cancer</rdfs:label>
        <skos:notation>DOID:0060073</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0060083 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0060083">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_2914"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer located_in the immune system that is characterized by uncontrolled cellular proliferation in organs of the immune system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:created_by>lschriml</oboInOwl:created_by>
        <oboInOwl:creation_date>2011-06-08T01:11:18Z</oboInOwl:creation_date>
        <oboInOwl:hasDbXref>ICDO:9392/3</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0060083</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <rdfs:label xml:lang="en">immune system cancer</rdfs:label>
        <skos:notation>DOID:0060083</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0060097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0060097">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_14566"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">An organ system benign neoplam that is located_in the thoracic cavity.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:created_by>lschriml</oboInOwl:created_by>
        <oboInOwl:creation_date>2011-07-15T01:55:57Z</oboInOwl:creation_date>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0060097</oboInOwl:id>
        <rdfs:label xml:lang="en">thoracic benign neoplasm</rdfs:label>
        <skos:notation>DOID:0060097</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0060100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0060100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_17"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer located_in the muscular and skeletal organs and characterized by uncontrolled cellular proliferation of the musculoskeletal organs.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:created_by>lschriml</oboInOwl:created_by>
        <oboInOwl:creation_date>2011-07-15T02:30:51Z</oboInOwl:creation_date>
        <oboInOwl:hasAlternativeId>DOID:0060124</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym xml:lang="en">skeletal system cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0060100</oboInOwl:id>
        <rdfs:label xml:lang="en">musculoskeletal system cancer</rdfs:label>
        <skos:notation>DOID:0060100</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0060119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0060119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3119"/>
        <obo:IAO_0000115 xml:lang="en">A gastrointestinal system cancer that is located_in the pharynx.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:created_by>lschriml</oboInOwl:created_by>
        <oboInOwl:creation_date>2011-07-27T01:26:34Z</oboInOwl:creation_date>
        <oboInOwl:hasDbXref>MESH:D010610</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3325</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126685009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0031347</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">pharyngeal neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">pharynx neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">pharyngeal cancer</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:0060119</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">pharynx cancer</rdfs:label>
        <skos:notation>DOID:0060119</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0080001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0080001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_65"/>
        <obo:IAO_0000115 xml:lang="en">A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1290</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:M89.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001847</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:76069003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0005940</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">skeletal disease</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:0080001</oboInOwl:id>
        <rdfs:label xml:lang="en">bone disease</rdfs:label>
        <skos:notation>DOID:0080001</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0080176 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0080176">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_9470"/>
        <obo:IAO_0000115 xml:lang="en">A bacterial meningitis that has_material_basis_in Neisseria meningitidis infection.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:A39.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:036.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008585</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0080176</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <rdfs:label xml:lang="en">meningococcal meningitis</rdfs:label>
        <skos:notation>DOID:0080176</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0080179 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0080179">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_9470"/>
        <obo:IAO_0000115 xml:lang="en">A bacterial meningitis that has_material_basis_in Haemophilus influenzae infection.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:G00.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:320.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008583</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0080179</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <rdfs:label xml:lang="en">haemophilus meningitis</rdfs:label>
        <skos:notation>DOID:0080179</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0080355 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0080355">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3119"/>
        <obo:IAO_0000115 xml:lang="en">A gastrointestinal system cancer that is located_in the hepatobiliary system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0080355</oboInOwl:id>
        <rdfs:label xml:lang="en">hepatobiliary system cancer</rdfs:label>
        <skos:notation>DOID:0080355</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0080600 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0080600">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2, a subtype of Betacoronavirus pandemicum.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:U07.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D000086382</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C171133</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:840539006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C5203670</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">2019 Novel Coronavirus (2019-nCoV)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">2019-nCoV infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">COVID19</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">SARS-CoV-2 infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Wuhan coronavirus infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Wuhan seafood market pneumonia virus infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0080600</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">COVID-19</rdfs:label>
        <skos:notation>DOID:0080600</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_0081267 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_0081267">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_2914"/>
        <obo:IAO_0000115 xml:lang="en">An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient&apos;s tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD11:4B24</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D006086</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:614395</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:39812</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">GvHD</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">graft versus host disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:0081267</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <rdfs:label xml:lang="en">graft-versus-host disease</rdfs:label>
        <skos:notation>DOID:0081267</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_10154 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_10154">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_10155"/>
        <obo:IAO_0000115 xml:lang="en">An intestinal cancer that is located_in the small intestine.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:9385</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C17</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:152.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7523</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:363509000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153425</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:10154</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">small intestine cancer</rdfs:label>
        <skos:notation>DOID:10154</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_10155 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_10155">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3119"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_5295"/>
        <obo:IAO_0000115 xml:lang="en">A gastrointestinal system cancer that is located_in the intestine.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:C26.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:159.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D007414</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4572</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93838000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0346627</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant intestinal tumors</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of intestine</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:10155</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">intestinal cancer</rdfs:label>
        <skos:notation>DOID:10155</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_10264 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_10264">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_77"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results in inflammation located in salivary gland, has_material_basis_in Mumps rubulavirus, which is transmitted by droplet spread of saliva or mucus from the mouth, nose, or throat of an infected person, or transmitted by contaminated fomites. The infection has symptom fever, has symptom headache, has symptom muscle aches, has symptom tiredness, has symptom loss of appetite, has symptom swollen and tender salivary glands under the ears or jaw on one or both sides of the face.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:7116</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:B26</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:072</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009107</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C29888</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154352008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0026780</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:10264</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">mumps</rdfs:label>
        <skos:notation>DOID:10264</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_10283 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_10283">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3856"/>
        <obo:IAO_0000115 xml:lang="en">A male reproductive organ cancer that is located_in the prostate.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:514</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C61</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:185</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:05215</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D011471</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:176807</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:300147</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:300704</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:601518</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:602759</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:608656</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:608658</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:609299</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:609558</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:610321</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:610997</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:611100</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:611868</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:611928</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:611955</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:611958</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:611959</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3343</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7378</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:1331</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126906006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93974005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0033578</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0376358</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">NGP - new growth of prostate</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hereditary prostate cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of the prostate</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">prostate cancer, familial</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">prostate neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">prostatic cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">prostatic neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of the prostate</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:10283</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:comment xml:lang="en">Xref MGI. OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">prostate cancer</rdfs:label>
        <skos:notation>DOID:10283</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_104">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050117"/>
        <obo:IAO_0000115 xml:lang="en">A disease by infectious agent that results_in infection, has_material_basis_in Bacteria.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:A49.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001424</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2890</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:87628006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0004623</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:104</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">bacterial infectious disease</rdfs:label>
        <skos:notation>DOID:104</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_10534 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_10534">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3119"/>
        <obo:IAO_0000115 xml:lang="en">A gastrointestinal system cancer that is located_in the stomach.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:10539</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:10542</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:10543</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4713</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:7704</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C16</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C16.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C16.5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C16.6</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:151</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:151.4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:151.5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:151.6</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D013274</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:613659</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3387</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9331</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126824007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:269459004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:269460009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93717002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:94074003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0024623</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0038356</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153421</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153422</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153423</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">gastric cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">gastric neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:10534</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">stomach cancer</rdfs:label>
        <skos:notation>DOID:10534</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_10652 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_10652">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_331"/>
        <obo:IAO_0000115 xml:lang="en">A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:10254</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:G30</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:331.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:05010</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D000544</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2866</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:73768007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0002395</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Alzheimer disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Alzheimers dementia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:10652</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">Xref MGI. OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">Alzheimer&apos;s disease</rdfs:label>
        <skos:notation>DOID:10652</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_10844 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_10844">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_331"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in infection located_in brain, has_material_basis_in Japanese encephalitis virus (Orthoflavivirus japonicum), which is transmitted_by Culex tritaeniorhynchus mosquito bite. The infection has_symptom headache, has_symptom high fever, has_symptom neck stiffness, has_symptom stupor, has_symptom disorientation, has_symptom coma, has_symptom tremors, has_symptom convulsions, and has_symptom spastic paralysis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:6797</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A83.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:062.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D004672</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34577</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:266194002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0014057</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Japanese B encephalitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:10844</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">Japanese encephalitis</rdfs:label>
        <skos:notation>DOID:10844</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_229"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_28"/>
        <obo:IAO_0000115 xml:lang="en">A female reproductive system disease that is located_in the ovary.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>MESH:D010049</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C26841</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:5552004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0029928</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1100</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">ovarian disease</rdfs:label>
        <skos:notation>DOID:1100</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3996"/>
        <obo:IAO_0000115 xml:lang="en">An urinary system cancer that results_in malignant growth located_in the urinary bladder.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:5428</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:12210</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C67</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:188</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:05219</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001749</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:109800</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2901</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9334</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126885006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:363455001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0005684</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0005695</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">bladder cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of the bladder</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:11054</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">urinary bladder cancer</rdfs:label>
        <skos:notation>DOID:11054</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:IAO_0000115 xml:lang="en">A brucellosis that involves an infection caused by Brucella suis [NCBITaxon:29461] in swine and humans. The disease has_symptom fever, has_symptom chills, has_symptom malaise, has_symptom diaphoresis, has_symptom arthralgia, has_symptom myalgia, has_symptom headache, has_symptom anorexia, and has_symptom fatigue.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:11076</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">Brucella suis brucellosis</rdfs:label>
        <skos:notation>DOID:11076</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11077 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11077">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that is caused by the bacteria of the genus Brucella, when humans come in contact with contaminated animals or animal products or ingestion of infected food products. The disease has_symptom fever, has_symptom sweat, has_symptom headache, has_symptom back pain, has_symptom physical weakness, has_symptom joint pain and has_symptom fatigue.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:0050060</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:5966</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A23</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:023</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C84602</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154296006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0006309</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Maltese fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">undulant fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">Bang&apos;s disease</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">Gibraltar fever</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">Malta fever</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">Mediterranean fever</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:11077</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">brucellosis</rdfs:label>
        <skos:notation>DOID:11077</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that is a zoonotic infectious disease affecting multiple organs, has_material_basis_in Coxiella burnetii, which is transmitted_by inhalation of air contaminated by barnyard dust containing dried placental material, birth fluids, or excreta of infected herd animals, transmitted_by ingestion of contaminated milk, transmitted_by tick bites and transmitted_by contact with infected person. The infection has_symptom fever, has_symptom headache, has_symptom cough, has_symptom pleuritic chest pain, has_symptom myalgia and has_symptom arthralgia.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:7515</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A78</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:083.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D011778</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34970</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:266205000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0034362</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Infection due to Coxiella burnetii</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:11100</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">Q fever</rdfs:label>
        <skos:notation>DOID:11100</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1115 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1115">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050687"/>
        <obo:IAO_0000115 xml:lang="en">A cell type cancer that has_material_basis_in abnormally proliferating cells derives from embryonic mesoderm.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:3936</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C49</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:171.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:8800/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93765001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153519</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">connective and soft tissue neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of soft tissue and skeleton</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1115</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">sarcoma</rdfs:label>
        <skos:notation>DOID:1115</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1116 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1116">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_104"/>
        <obo:IAO_0000115 xml:lang="en">A commensal bacterial infectious disease that results_in inflammation located_in respiratory tract, has_material_basis_in Bordetella pertussis, or has_material_basis_in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by a prolonged, high-pitched, deeply indrawn breath (whoop).</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:11333</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:11751</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>KEGG:05133</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001885</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:26484003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0006015</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">WC - Whooping cough</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">bordetella infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">whooping cough</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1116</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <rdfs:label xml:lang="en">pertussis</rdfs:label>
        <skos:notation>DOID:1116</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11166 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11166">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that has_material_basis_in human papillomaviruses, which establish productive infections only in the stratified epithelium of the skin or mucous membranes. These viruses cause warts and sometimes tumors. They are transmitted_by sexual contact.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>MESH:D030361</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">HPV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:11166</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <rdfs:label xml:lang="en">Human papillomavirus infectious disease</rdfs:label>
        <skos:notation>DOID:11166</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11260 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11260">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results in inflammation located in brain or located in spinal cord, has_material_basis_in Rabies virus, which is transmitted by bite of an infected animal, or transmitted by contact of mucous membranes with saliva of an infected animal. The infection has symptom fever, has symptom headache, has symptom prickling or itching sensation at the site of bite, has symptom anxiety, has symptom confusion, has symptom agitation, has symptom delirium, has symptom difficulty swallowing, has symptom hydrophobia, and has symptom paralysis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:7516</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A82</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:071</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D011818</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C28182</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:14168008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0034494</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Lyssa</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:11260</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">rabies</rdfs:label>
        <skos:notation>DOID:11260</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11338 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11338">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that results in prolonged contraction of skeletal muscle fibers, has_material_basis_in Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord, where it binds irreversibly to receptors inhibiting neurotransmission. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:5144</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A35</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:037</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D013742</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C85185</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154312006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0039614</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Infection due to Clostridium tetani</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">clostridial tetanus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:11338</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-positive_bacterial_infectious_disease"/>
        <rdfs:label xml:lang="en">tetanus</rdfs:label>
        <skos:notation>DOID:11338</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11405 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11405">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that is characterized by sore throat, low fever, and an adherent membrane (a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. A milder form of diphtheria can be restricted to the skin. It is caused by Corynebacterium diphtheriae, an aerobic Gram-positive bacterium. Diphtheria toxin spreads through the bloodstream and can lead to potentially life-threatening complications that affect other organs of the body, such as the heart and kidneys.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:4132</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:1875</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D003354</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:397434007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0010153</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">corynebacterium infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:11405</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-positive_bacterial_infectious_disease"/>
        <rdfs:label xml:lang="en">diphtheria</rdfs:label>
        <skos:notation>DOID:11405</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11729 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11729">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia burgdorferi, which is transmitted_by blacklegged tick (Ixodes scapularis) or transmitted_by western blacklegged tick (Ixodes pacificus). The infection has_symptom fever, has_symptom headache, has_symptom fatigue, and has_symptom skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:12233</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:12073</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A69.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:088.81</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008193</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D020852</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C45161</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154376000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:715507005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0024198</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0752235</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Bannwarth syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Bannworth&apos;s syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Lyme borreliosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Neurological Lyme disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">lyme neuroboInOwlrreliosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neuroboInOwlrreliosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:11729</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#tick-borne_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">Lyme disease</rdfs:label>
        <skos:notation>DOID:11729</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1192">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3093"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_574"/>
        <obo:IAO_0000115 xml:lang="en">A nervous system cancer that is located in the peripheral nervous system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:3194</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>MESH:D010524</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D018317</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3321</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4972</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126980002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:189946005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0031118</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0206727</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of peripheral nerve</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">nerve sheath neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of PNS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1192</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">peripheral nervous system neoplasm</rdfs:label>
        <skos:notation>DOID:1192</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_11934 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_11934">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:12425</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D006258</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3077</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:255055008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0018671</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">head and neck neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">head and neck tumours</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">head/neck neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of head and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:11934</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">head and neck cancer</rdfs:label>
        <skos:notation>DOID:11934</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_193"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_229"/>
        <obo:IAO_0000115 xml:lang="en">A reproductive organ cancer that is manifested in the female genitals. This includes organs such as the ovaries, fallopian tubes, uterus, cervix, vagina and vulva.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1244</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1281</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C57</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:184</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D005833</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3053</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4913</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126907002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:188207007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0017416</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153585</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0699889</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">female reproductive cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant Gynecologic tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of female genital organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:120</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">female reproductive organ cancer</rdfs:label>
        <skos:notation>DOID:120</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1205 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1205">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_2914"/>
        <obo:IAO_0000115 xml:lang="en">An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <obo:OBI_9991118>allergic disease</obo:OBI_9991118>
        <oboInOwl:hasDbXref>ICD10CM:T78.40</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D006967</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3114</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:257550005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0020517</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">allergic hypersensitivity disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hypersensitivity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hypersensitivity reaction type I disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1205</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">allergic disease</rdfs:label>
        <skos:notation>DOID:1205</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_12205 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_12205">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results in infection, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted by Aedes mosquito bite. The infection has symptom fever, has symptom severe headache, has symptom severe pain behind the eyes, has symptom joint pain, has symptom muscle and bone pain, has symptom rash, and has symptom mild bleeding.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:0050142</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:6254</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A90</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:061</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D003715</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34528</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:38362002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0011311</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Dengue Fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">breakbone fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">classic dengue</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">classical dengue</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:12205</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">dengue disease</rdfs:label>
        <skos:notation>DOID:12205</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_12365 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_12365">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_1398"/>
        <obo:IAO_0000115 xml:lang="en">A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:12552</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>EFO:0001068</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GARD:6961</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:B54</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:084</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008288</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34797</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:673</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154374002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0024530</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">induced malaria</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:12365</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">Xref MGI.</rdfs:comment>
        <rdfs:label xml:lang="en">malaria</rdfs:label>
        <skos:notation>DOID:12365</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1240 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1240">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_2531"/>
        <obo:IAO_0000115 xml:lang="en">A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:9145</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C95.90</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:208</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9800/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D007938</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3161</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:255049003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0023418</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1240</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">leukemia</rdfs:label>
        <skos:notation>DOID:1240</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_12549 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_12549">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis A virus (Hepatovirus ahepa), which is transmitted_by ingestion of contaminated food or water, or transmitted_by direct contact with an infected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:12547</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>MESH:D006506</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3096</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:40468003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0019159</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Viral hepatitis, type A</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">Viral hepatitis A</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:12549</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">hepatitis A</rdfs:label>
        <skos:notation>DOID:12549</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1273">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus, which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>MESH:D018357</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3354</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:186750007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0035235</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">RSV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">respiratory syncytial virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1273</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">respiratory syncytial virus infectious disease</rdfs:label>
        <skos:notation>DOID:1273</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3620"/>
        <obo:IAO_0000115 xml:lang="en">A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:2125</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2126</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:3543</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:6649</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:911</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C71</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:191</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:239.6</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001932</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C170814</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2907</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3568</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C5115</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7710</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126952004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:428061005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93727008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0006118</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153633</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0220624</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0750974</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0750979</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1334557</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">BT - Brain tumour</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">adult brain tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">adult malignant brain neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">brain neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">brain neoplasm, adult</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant brain tumour</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant primary brain neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant primary brain tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of Brain</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of adult brain</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of brain</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">primary brain neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">primary brain tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">primary malignant neoplasm of brain</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of the Brain</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1319</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">brain cancer</rdfs:label>
        <skos:notation>DOID:1319</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1324 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1324">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050615"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_850"/>
        <obo:IAO_0000115 xml:lang="en">A respiratory system cancer that is located_in the lung.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:13075</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1322</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9881</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C34.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C34.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C34.3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:162.3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:162.4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:162.5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:162.8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:211980</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:608935</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:612571</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:612593</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:614210</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187860004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187864008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187868006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187874006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0024624</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153491</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153492</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153493</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">lung neoplasm</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:1324</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">lung cancer</rdfs:label>
        <skos:notation>DOID:1324</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_13258 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_13258">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that is a communicable systemic illness, has_material_basis_in Salmonella enterica subsp enterica serovar Typhi, which is transmitted_by ingestion of food or water contaminated with the feces of an infected person. The infection has_symptom fever, has_symptom diarrhea, has_symptom prostration, has_symptom headache, has_symptom splenomegaly, has_symptom liver enlargement, has_symptom eruption of rose-colored spots, and has_symptom leukopenia.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:3054</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:9564</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A01.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:002.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D014435</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C35089</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:186091002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0041466</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Typhoid</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:13258</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <rdfs:label xml:lang="en">typhoid fever</rdfs:label>
        <skos:notation>DOID:13258</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1398 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1398">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050117"/>
        <obo:IAO_0000115 xml:lang="en">A disease by infectious agent that is carried out by a parasite which by definition is a pathogen that simultaneously injures and derives sustenance from its host.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:11681</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:13509</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1396</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1494</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2114</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2293</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2922</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:3564</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4191</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:886</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:948</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9639</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9644</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:H44.12</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:360.13</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34587</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:57100005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0014238</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Ectoparasitic disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">parasitemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1398</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">parasitic infectious disease</rdfs:label>
        <skos:notation>DOID:1398</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_14067 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_14067">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:IAO_0000115 xml:lang="en">A malaria described as a severe form of the disease caused by a parasite Plasmodium falciparum, which is marked by irrregular recurrence of paroxysms and prolonged or continuous fever.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:B50</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:084.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D016778</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34798</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:62676009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0024535</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Malaria fever, subtertian</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">falciparum malaria</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tertian fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:14067</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">Plasmodium falciparum malaria</rdfs:label>
        <skos:notation>DOID:14067</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_14456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_14456">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:IAO_0000115 xml:lang="en">A brucellosis that involves an infection caused by Brucella melitensis [NCBITaxon:29459] in cattle, goats, sheep and humans. The disease has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom limb pain and has_symptom back pain.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:A23.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:023.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:186305007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0302362</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:14456</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">Brucella melitensis brucellosis</rdfs:label>
        <skos:notation>DOID:14456</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_14457 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_14457">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:IAO_0000115 xml:lang="en">A brucellosis that involves an infection caused by Brucella abortus [NCBITaxon:235] in cattle and humans. The disease has_symptom fever, has_symptom chills, has_symptom sweats, has_symptom weight loss, has_symptom malaise, has_symptom headaches, has_symptom myalgia, and has_symptom arthralgia.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:A23.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:023.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:427795000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0302363</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:14457</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">Brucella abortus brucellosis</rdfs:label>
        <skos:notation>DOID:14457</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_14566 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_14566">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4"/>
        <obo:IAO_0000115 xml:lang="en">A disease that is characterized by abnormally rapid cell division.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <obo:OBI_9991118>neoplasm</obo:OBI_9991118>
        <oboInOwl:hasAlternativeId>DOID:0000818</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym xml:lang="en">cell process disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:14566</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <rdfs:label xml:lang="en">disease of cellular proliferation</rdfs:label>
        <skos:notation>DOID:14566</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1498 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1498">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that is described as an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae, which is characterized by profuse watery diarrhea, vomiting, leg cramps, circulatory collapse and shock.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:6043</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A00</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002771</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:186087007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0008354</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Cholera - Vibrio cholerae</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Cholera due to Vibrio cholerae</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Vibrio cholerae</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1498</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#GOLD"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <rdfs:label xml:lang="en">cholera</rdfs:label>
        <skos:exactMatch>MESH:D002771</skos:exactMatch>
        <skos:notation>DOID:1498</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_15 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_15">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">A disease of anatomical entity that is located_in reproductive system organs.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:6309</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>NCI:C27613</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1335037</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">genital system disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:15</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">reproductive system disease</rdfs:label>
        <skos:notation>DOID:15</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1542 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1542">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_11934"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_305"/>
        <obo:IAO_0000115 xml:lang="en">A head and neck cancer that has_material_basis_in epithelial cells and is located in the upper aerodigestive tract, including the lip, oral cavity (mouth), nasal cavity, paranasal sinuses, pharynx, and larynx.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>NCI:C6077</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1334927</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">carcinoma of the neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">carcinoma of neck</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:1542</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">head and neck carcinoma</rdfs:label>
        <skos:notation>DOID:1542</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1579 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1579">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:3226</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:J98</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:519</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:155603009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0029582</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1579</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <rdfs:label xml:lang="en">respiratory system disease</rdfs:label>
        <skos:notation>DOID:1579</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1586 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1586">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_104"/>
        <obo:IAO_0000115 xml:lang="en">A connective tissue disease that develops from an antecedent Group A Streptococcal pharyngeal infection and has_symptom carditis, has_symptom polyarthritis, has_symptom chorea, has_symptom erythema marginatum, has_symptom subcutaneous nodules, has_symptom arthralgia, has_symptom prolonged PR interval, and/or has_symptom fever.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1006</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1007</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:5699</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:I00</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:I00-I02</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:390</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:390-392.99</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012213</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34984</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:155265007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:274095001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0035436</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0264743</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">ACUTE RHEUMATIC FEVER</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">RhF - Rheumatic fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1586</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-positive_bacterial_infectious_disease"/>
        <rdfs:label xml:lang="en">rheumatic fever</rdfs:label>
        <skos:exactMatch>MESH:D012213</skos:exactMatch>
        <skos:notation>DOID:1586</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1612 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1612">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer that originates in the mammary gland.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1648</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4241</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C50</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001943</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:114480</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9335</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:254837009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0006142</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">breast tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of breast</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of the breast</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">mammary cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">mammary tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">primary breast cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">mammary neoplasm</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:1612</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:comment xml:lang="en">Xref MGI. OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">breast cancer</rdfs:label>
        <skos:notation>DOID:1612</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_162">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_14566"/>
        <obo:IAO_0000115 xml:lang="en">A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:C80.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:199</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:8000/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009369</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9305</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:269513004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0006826</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">primary cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:162</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">Updating out dated UMLS CUI.</rdfs:comment>
        <rdfs:label xml:lang="en">cancer</rdfs:label>
        <skos:notation>DOID:162</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_17 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_17">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">A disease of anatomical entity that occurs in the muscular and/or skeletal system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>MESH:D009140</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C107377</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:268047003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0026857</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:17</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">musculoskeletal system disease</rdfs:label>
        <skos:notation>DOID:17</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_170 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_170">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer located_in endocrine system that is characterized by uncontrolled cellular proliferation of the hormone producing glands of the endocrine system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:10009</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C75.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:194.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D004701</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3010</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3575</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:127015005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93780007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0014132</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153658</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Endocrine tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">endocrine neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant Endocrine tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of endocrine gland</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumour of endocrine gland</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of endocrine gland</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of endocrine system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:170</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">endocrine gland cancer</rdfs:label>
        <skos:notation>DOID:170</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1789 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1789">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0060097"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>NCI:C7633</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1377610</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Mesothelioma of Peritoneum</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1789</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">benign peritoneal mesothelioma</rdfs:label>
        <skos:notation>DOID:1789</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1793 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1793">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_170"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_28"/>
        <obo:IAO_0000115 xml:lang="en">An endocrine gland cancer located_in the pancreas.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:14356</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1797</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:3588</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9859</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:9364</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C25.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C25.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C25.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:157.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:157.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:157.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:157.8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:05212</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D010190</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3305</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:1333</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:217074</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126859007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187796007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93715005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93823001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:94082003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0030297</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153458</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153459</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153460</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153463</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Ca body of pancreas</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ca head of pancreas</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ca tail of pancreas</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of body of pancreas</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of head of pancreas</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of tail of pancreas</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">pancreas neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">pancreatic neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">pancreatic tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1793</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:comment xml:lang="en">Xref MGI.</rdfs:comment>
        <rdfs:label xml:lang="en">pancreatic cancer</rdfs:label>
        <skos:notation>DOID:1793</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_18 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_18">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:579</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>NCI:C27599</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1335051</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Non-neoplastic urinary tract disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">urinary tract disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:18</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">urinary system disease</rdfs:label>
        <skos:notation>DOID:18</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_184">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0080001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_201"/>
        <obo:IAO_0000115 xml:lang="en">A connective tissue cancer that is located_in bone and is characterized by uncontrolled cellular proliferation that destroys normal bone tissue.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:3348</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>MESH:D001859</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9343</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126537000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0005967</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">CA - bone cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">bone neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">bone tumour</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant bone neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant bone tumour</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of bone</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant osseous tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of bone</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">osseous tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:184</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">bone cancer</rdfs:label>
        <skos:notation>DOID:184</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1909 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1909">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050687"/>
        <obo:IAO_0000115 xml:lang="en">A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0000756</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:8720/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:05218</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008545</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3224</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:2092003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0025202</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Naevocarcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant melanoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1909</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">melanoma</rdfs:label>
        <skos:exactMatch>MESH:D008545</skos:exactMatch>
        <skos:notation>DOID:1909</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_193 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_193">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_15"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer that is manifested in the reproductive organs.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1900</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>NCI:C3674</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0178830</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Reproductive tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant reproductive system neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">cancer of reproductive system</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:193</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">reproductive organ cancer</rdfs:label>
        <skos:notation>DOID:193</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1936 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1936">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0003914</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:I70</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:440</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D050197</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C35768</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:155414001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0004153</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1936</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">atherosclerosis</rdfs:label>
        <skos:exactMatch>MESH:D050197</skos:exactMatch>
        <skos:notation>DOID:1936</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1964 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1964">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_120"/>
        <obo:IAO_0000115 xml:lang="en">A female reproductive organ cancer that is located_in fallopian tube.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1961</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:9162</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C57.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:183.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D005185</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3032</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7480</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126916003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93794008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0015558</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153579</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">fallopian tube neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of uterine tube</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of fallopian tube</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumour of fallopian tube</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of fallopian tube</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of the fallopian tube</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor, fallopian tube, malignant</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:1964</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">fallopian tube cancer</rdfs:label>
        <skos:notation>DOID:1964</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_1993 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_1993">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
        <obo:IAO_0000115 xml:lang="en">A colorectal cancer that is located_in the rectum.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1989</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C20</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:154.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7418</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9382</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:254582000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93984006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0007113</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0949022</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">carcinoma of rectum</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">carcinoma of the rectum</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant Rectal tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of rectum</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant rectum tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of rectum</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">rectal cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">cancer of rectum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:1993</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">rectum cancer</rdfs:label>
        <skos:notation>DOID:1993</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_201 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_201">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0060100"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_65"/>
        <obo:IAO_0000115 xml:lang="en">A musculoskeletal system cancer that is located_in connective tissue.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>MESH:D009372</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126598008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0027656</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Tumour of connective tissue</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">connective tissue neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">mesenchymal tissue malignant neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of connective tissues</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:201</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">connective tissue cancer</rdfs:label>
        <skos:notation>DOID:201</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_2043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_2043">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:12591</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:12592</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2042</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>EFO:0004197</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D006509</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3097</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:66071002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0019163</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">chronic hepatitis B</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hepatitis B infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">Serum hepatitis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:2043</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#sexually_transmitted_infectious_disease"/>
        <rdfs:label xml:lang="en">hepatitis B</rdfs:label>
        <skos:notation>DOID:2043</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_2123 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_2123">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that has_material_basis_in Francisella tularensis, which is transmitted by dog tick bite (Dermacentor variabilis), transmitted by deer flies (Chrysops sp) or transmitted by contact with infected animal tissues.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:396</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:021.8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:186298002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0029835</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:2123</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-negative_bacterial_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#tick-borne_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">tularemia</rdfs:label>
        <skos:notation>DOID:2123</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_219 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_219">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
        <obo:IAO_0000115 xml:lang="en">A colorectal cancer that is located_in the colon.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:C18</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:153</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D003110</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9242</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:363406005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0007102</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:219</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">colon cancer</rdfs:label>
        <skos:notation>DOID:219</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_229">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_15"/>
        <obo:IAO_0000115 xml:lang="en">A reproductive system disease that impairs the ability to reproduce and is located in the uterus, vagina, cervix, ovaries or fallopian tubes.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD9CM:629.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D005831</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:38233001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0017411</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:229</oboInOwl:id>
        <rdfs:label xml:lang="en">female reproductive system disease</rdfs:label>
        <skos:notation>DOID:229</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_2394 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_2394">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_1100"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_120"/>
        <obo:IAO_0000115 xml:lang="en">A female reproductive organ cancer that is located_in the ovary.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:0060070</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2144</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9595</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:7295</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C56</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:183.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D010051</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:167000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:607893</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4984</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7431</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:213500</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:213517</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:123843001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:372117006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93934004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0919267</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1140680</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1299247</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant Ovarian tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumour of ovary</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">ovarian neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">ovary neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">primary ovarian cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of the Ovary</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:2394</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:comment xml:lang="en">Xref MGI. OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">ovarian cancer</rdfs:label>
        <skos:notation>DOID:2394</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_2531 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_2531">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_74"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1034</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2532</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>MESH:D019337</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C27134</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:414388001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0376544</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Hematologic malignancy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Hematologic neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Hematological tumors</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">blood cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hematopoietic and lymphoid system tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hematopoietic cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hematopoietic neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hematopoietic tumors</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant hematopoietic neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:2531</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">hematologic cancer</rdfs:label>
        <skos:notation>DOID:2531</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_263 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_263">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3996"/>
        <obo:IAO_0000115 xml:lang="en">A urinary system cancer that is located_in the kidney.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:11834</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:3676</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C64</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:189.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D007680</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C120456</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3150</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7548</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126880001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93849006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0022665</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0494158</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0740457</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of kidney except pelvis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumour of kidney</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">renal cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:263</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">kidney cancer</rdfs:label>
        <skos:notation>DOID:263</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_28 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_28">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">A disease of anatomical entity that is located_in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:E34.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:259.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D004700</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:67432001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0014130</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:28</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">endocrine system disease</rdfs:label>
        <skos:notation>DOID:28</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_2914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_2914">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">A disease of anatomical entity that is located_in the immune system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0000540</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:D89.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:279.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154782004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0041806</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:2914</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <rdfs:label xml:lang="en">immune system disease</rdfs:label>
        <skos:notation>DOID:2914</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_299 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_299">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_305"/>
        <obo:IAO_0000115 xml:lang="en">A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICDO:8140/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D000230</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2852</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:35917007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0001418</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:299</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">adenocarcinoma</rdfs:label>
        <skos:exactMatch>MESH:D000230</skos:exactMatch>
        <skos:notation>DOID:299</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_305 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_305">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050687"/>
        <obo:IAO_0000115 xml:lang="en">A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:2428</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:6570</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICDO:8010/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002277</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009375</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2916</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3709</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:188083002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:269513004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:71298006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0007097</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0553707</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1368683</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">epithelial cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">epithelioma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant Epithelioma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:305</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">carcinoma</rdfs:label>
        <skos:notation>DOID:305</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3068 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3068">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3069"/>
        <obo:IAO_0000115 xml:lang="en">A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:3075</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:3080</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:2491</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9440/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D005909</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C129295</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C39750</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9094</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:63634009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0017636</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0278878</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1514422</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">GBM</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">adult glioblastoma multiforme</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">glioblastoma multiforme</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">grade IV adult Astrocytic tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">primary glioblastoma multiforme</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">spongioblastoma multiforme</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3068</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">glioblastoma</rdfs:label>
        <skos:notation>DOID:3068</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3069 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3069">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050687"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3620"/>
        <obo:IAO_0000115 xml:lang="en">A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:4861</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICDO:9400/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001254</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4951</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C60781</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:189914005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:99131000119108</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0004114</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0750935</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Astrocytic tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">astrocytoma of Cerebrum</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">astrocytoma of brain</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">astroglioma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">cerebral astrocytoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3069</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">malignant astrocytoma</rdfs:label>
        <skos:exactMatch>MESH:D001254</skos:exactMatch>
        <skos:notation>DOID:3069</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3093">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_863"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer located_in the nervous system that affects the central or peripheral nervous system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1193</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:3195</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4695</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD9CM:192.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009380</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C35562</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:188306000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0027665</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153643</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1334956</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of nervous system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of nervous system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">nervous system neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neural neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neural tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of the nervous system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3093</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">nervous system cancer</rdfs:label>
        <skos:notation>DOID:3093</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3118 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3118">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_77"/>
        <obo:IAO_0000115 xml:lang="en">A gastrointestinal system disease that is located_in the liver and/or biliary tract.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>MESH:D004066</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3959</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0267792</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">liver and biliary tract disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3118</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">hepatobiliary disease</rdfs:label>
        <skos:notation>DOID:3118</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_77"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:4945</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8377</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C26.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:239.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D004067</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D005770</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3052</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4890</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:128348002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:276806006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:428905002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0012243</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0017185</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0685938</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">GI tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">digestive system cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">gastrointestinal tract cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3119</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">gastrointestinal system cancer</rdfs:label>
        <skos:notation>DOID:3119</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3292">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results in infection of primates, rodents and humans, located in skin, has_material_basis_in Monkeypox virus (Orthopoxvirus monkeypox), which is transmitted by contact with the animal&apos;s blood, body fluids, rash, or with the body fluids of a sick person, transmitted by fomites, and transmitted by respiratory droplets. The infection has symptom fever, has symptom muscle ache, has symptom headache, and has symptom lymphadenopathy.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:10722</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:B04</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:059.01</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D045908</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C128421</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:240466002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0276180</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">monkeypox</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3292</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:comment xml:lang="en">November 2022 WHO name update.</rdfs:comment>
        <rdfs:label xml:lang="en">mpox</rdfs:label>
        <skos:notation>DOID:3292</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_331 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_331">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_863"/>
        <obo:IAO_0000115 xml:lang="en">A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:G96.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002493</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2934</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:267144009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0007682</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:331</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">central nervous system disease</rdfs:label>
        <skos:notation>DOID:331</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3347 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3347">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_184"/>
        <obo:IAO_0000115 xml:lang="en">A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:183</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:7284</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9180/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012516</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D018213</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:259500</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9145</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:668</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:189878003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0029463</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0206639</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Osteogenic sarcoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Skeletal sarcoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">bone tissue neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">osteoid sarcoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3347</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">osteosarcoma</rdfs:label>
        <skos:notation>DOID:3347</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3369 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3369">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_201"/>
        <obo:IAO_0000115 xml:lang="en">A connective tissue cancer that has_material_basis_in neural crest cells derives_from undeveloped, undifferentiated neuroectoderm.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:0050607</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4158</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4390</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4391</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4392</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:4980</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:6390</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9364/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:C563168</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012512</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D018241</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:612219</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C27901</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C27903</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4817</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7542</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7806</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9341</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:134210007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:73676002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:76909002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0553580</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0684337</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0796547</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0863029</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0877849</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1334408</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Ewing&apos;s family localized tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ewing&apos;s sarcoma/peripheral primitive neuroectodermal tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ewing&apos;s tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ewings sarcoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ewings sarcoma-primitive neuroectodermal tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">PNET of Thoracopulmonary Region</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">localized Ewing sarcoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">localized Ewing&apos;s sarcoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">localized Ewing&apos;s sarcoma/peripheral primitive neuroectodermal tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">localized Ewing&apos;s tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">localized peripheral primitive neuroectodermal tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">peripheral primitive neuroectodermal tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3369</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">Ewing sarcoma</rdfs:label>
        <skos:notation>DOID:3369</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_345 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_345">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_229"/>
        <obo:IAO_0000115 xml:lang="en">A female reproductive system disease that is located_in the uterus.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:N85.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:621.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D014591</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C26907</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:237068005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0042131</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:345</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">uterine disease</rdfs:label>
        <skos:notation>DOID:345</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3571 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3571">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0080355"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_170"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3118"/>
        <obo:IAO_0000115 xml:lang="en">A hepatobiliary system cancer that is located_in the liver.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:12300</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:269</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:7330</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:915</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:919</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C22.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C22.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:155.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:155.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008113</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34803</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7692</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126851005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187771009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93870000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0023903</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0024620</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0345904</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0854795</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Ca liver - primary</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Resectable malignant neoplasm of Liver</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hepatic cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hepatic neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant hepato-biliary neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of liver</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of liver, not specified as primary or secondary</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of liver, primary</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of liver</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of liver</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">non-resectable primary hepatic malignant neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">primary liver cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">primary malignant neoplasm of liver</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">resectable malignant neoplasm of the liver</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3571</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">liver cancer</rdfs:label>
        <skos:notation>DOID:3571</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3620 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3620">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3093"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_331"/>
        <obo:IAO_0000115 xml:lang="en">A nervous system cancer that is located_in the central nervous system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:0060093</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1318</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>EFO:0000326</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C72.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D016543</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4627</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9293</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126951006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93744007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0085136</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0348374</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">CNS neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">central nervous system tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">central nervous system tumors</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of central nervous system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of CNS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of central nervous system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3620</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">central nervous system cancer</rdfs:label>
        <skos:notation>DOID:3620</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_363 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_363">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_120"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_345"/>
        <obo:IAO_0000115 xml:lang="en">A female reproductive organ cancer that is located_in the uterus.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:4363</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C55</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:179</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D014594</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3435</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3552</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126908007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:371973000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0042138</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153567</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">CA - cancer of uterus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Tumour of uterus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of uterus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant uterine tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of uterus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">uterine tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">uterus neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:363</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">uterine cancer</rdfs:label>
        <skos:notation>DOID:363</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3717 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3717">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_299"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_5517"/>
        <obo:IAO_0000115 xml:lang="en">A stomach carcinoma that derives_from epithelial cells of glandular origin.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>NCI:C4004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:408647009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0278701</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">adenocarcinoma of stomach</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">stomach adenocarcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3717</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">gastric adenocarcinoma</rdfs:label>
        <skos:notation>DOID:3717</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3856 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3856">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_193"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_48"/>
        <obo:IAO_0000115 xml:lang="en">A reproductive organ cancer that is manifested in the male genital system. This includes organs such as the penis and scrotum.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:10284</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C63.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:187.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D005834</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3054</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C8561</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126895004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:363515000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0017417</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153606</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">male genital cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">male reproductive system neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of male genital organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of male genital organ or tract</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of male genital organs</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of male Reproductive system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of male genital organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of male genital organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of male Reproductive system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">male genital neoplasm</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:3856</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">male reproductive organ cancer</rdfs:label>
        <skos:notation>DOID:3856</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3905 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3905">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_305"/>
        <obo:IAO_0000115 xml:lang="en">A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0001071</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4878</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154485001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0684249</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">cancer of lung</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">carcinoma of lung</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:3905</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">lung carcinoma</rdfs:label>
        <skos:notation>DOID:3905</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3908 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3908">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3905"/>
        <obo:IAO_0000115 xml:lang="en">A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0003060</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:05223</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002289</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2926</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:254637007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0007131</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">NSCLC</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Non-small cell lung cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">non-small cell lung carcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3908</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">lung non-small cell carcinoma</rdfs:label>
        <skos:notation>DOID:3908</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_399 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_399">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:10096</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:12688</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:12691</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:415</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9901</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9902</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:7827</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D014375</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:15202009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0041295</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:399</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-positive_bacterial_infectious_disease"/>
        <rdfs:label xml:lang="en">tuberculosis</rdfs:label>
        <skos:exactMatch>MESH:D014376</skos:exactMatch>
        <skos:notation>DOID:399</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_3996 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_3996">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050686"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_18"/>
        <obo:IAO_0000115 xml:lang="en">An organ system cancer that is located_in the kidneys, ureteres, bladder or urethra.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:C68.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:189.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:448233000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0348371</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:3996</oboInOwl:id>
        <rdfs:label xml:lang="en">urinary system cancer</rdfs:label>
        <skos:notation>DOID:3996</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_4 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_4">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <obo:IAO_0000115 xml:lang="en">A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>MESH:D004194</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2991</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:64572001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0012634</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:4</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">disease</rdfs:label>
        <skos:notation>DOID:4</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_417 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_417">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_2914"/>
        <obo:IAO_0000115 xml:lang="en">An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <obo:OBI_9991118>autoimmune disease</obo:OBI_9991118>
        <oboInOwl:hasDbXref>ICD9CM:720</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:109100</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0003089</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">autoimmune hypersensitivity disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">hypersensitivity reaction type II disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:417</oboInOwl:id>
        <rdfs:comment xml:lang="en">Xref MGI.</rdfs:comment>
        <rdfs:label xml:lang="en">autoimmune disease</rdfs:label>
        <skos:notation>DOID:417</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_4325 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_4325">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that is a hemorrhagic fever, has_material_basis_in Bundibugyo virus (Orthoebolavirus bundibugyoense), Sudan ebolavirus (Orthoebolavirus sudanense), Tai Forest ebolavirus (Orthoebolavirus taiense), or Zaire ebolavirus (Orthoebolavirus zairense), which are transmitted_by contact with the body fluids of an infected animal or person, transmitted by contaminated fomites, or transmitted by infected medical equipment. The infection has_symptom fever, has_symptom headache, has_symptom joint pain, has_symptom muscle aches, has_symptom sore throat, has_symptom weakness, has_symptom diarrhea, has_symptom vomiting, has_symptom stomach pain, has_symptom rash, has_symptom red eyes, has_symptom hiccups, and has_symptom internal and external bleeding.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:2035</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A98.4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D019142</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C36171</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:123323003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0282687</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Ebola</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ebola disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ebola hemorrhagic fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:4325</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">Ebola virus disease</rdfs:label>
        <skos:notation>DOID:4325</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_4362 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_4362">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_363"/>
        <obo:IAO_0000115 xml:lang="en">A female reproductive organ cancer that is located_in the cervix.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:4361</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C53</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:180</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002583</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:603956</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2940</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9311</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:123841004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:254885005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0007847</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0007873</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">cervical neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">cervix cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">cervix uteri cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">neoplasm of uterine cervix</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">tumor of the Cervix Uteri</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">uterine cervical neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:4362</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">cervical cancer</rdfs:label>
        <skos:notation>DOID:4362</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_4606 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_4606">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0080355"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3118"/>
        <obo:IAO_0000115 xml:lang="en">A biliary tract cancer that is located_in the bile duct.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:10019</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C24.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:156.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001650</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2898</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7483</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93790004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0005396</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153453</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Ca extrahepatic bile ducts</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">bile duct tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of the extrahepatic bile duct</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:4606</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">bile duct cancer</rdfs:label>
        <skos:notation>DOID:4606</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_48 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_48">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_15"/>
        <obo:IAO_0000115 xml:lang="en">A reproductive system disease that affects male reproductive organs.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:N50.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:608.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D005832</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:64557000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0017412</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:48</oboInOwl:id>
        <rdfs:label xml:lang="en">male reproductive system disease</rdfs:label>
        <skos:notation>DOID:48</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_4896 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_4896">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_299"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4897"/>
        <obo:IAO_0000115 xml:lang="en">A bile duct carcinoma that derives_from epithelial cells of glandular origin.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>NCI:C27813</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:70179006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1370800</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:4896</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">bile duct adenocarcinoma</rdfs:label>
        <skos:notation>DOID:4896</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_4897 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_4897">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_305"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4606"/>
        <obo:IAO_0000115 xml:lang="en">A bile duct cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>MESH:D001650</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C27814</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:70179006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0740277</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:4897</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">bile duct carcinoma</rdfs:label>
        <skos:notation>DOID:4897</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_4947 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_4947">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4896"/>
        <obo:IAO_0000115 xml:lang="en">A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:5249</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C22.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:8160/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D018281</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4436</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C8265</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:70179006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0206698</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0280725</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">adult primary Cholangiocarcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">adult primary cholangiocellular carcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">cholangiosarcoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:4947</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">cholangiocarcinoma</rdfs:label>
        <skos:notation>DOID:4947</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_4953 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_4953">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_574"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results in destruction located in motor neurons, has_material_basis_in Human poliovirus 1, has_material_basis_in Human poliovirus 2, or has_material_basis_in Human poliovirus 3, which are transmitted by ingestion of food or water contaminated with feces, or transmitted by direct contact with the oral secretions. The infection has symptom fever, has symptom sore throat, has symptom headache, has symptom vomiting, has symptom fatigue, has symptom neck stiffness, has symptom muscle spasms, and has symptom acute flaccid paralysis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:7413</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A80</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:045</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D011051</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C35550</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:54839009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0032371</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:4953</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">poliomyelitis</rdfs:label>
        <skos:notation>DOID:4953</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_4960 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_4960">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_2531"/>
        <obo:IAO_0000115 xml:lang="en">A hematopoietic cancer that derives_from the blood-forming stem cells of the bone marrow.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:2356</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2761</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>EFO:0004251</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:D47.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009196</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:128925001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0027022</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">bone Marrow tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">bone marrow neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant bone Marrow tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of bone marrow</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:4960</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <rdfs:label xml:lang="en">bone marrow cancer</rdfs:label>
        <skos:notation>DOID:4960</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_5041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_5041">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3119"/>
        <obo:IAO_0000115 xml:lang="en">A gastrointestinal system cancer that is located_in the esophagus.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:10291</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:10292</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:10448</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1102</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1104</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:6383</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C15.3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C15.4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C15.5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:150.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:150.3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:150.4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:150.5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:150.8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D004938</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:133239</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3028</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3533</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3534</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3535</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4764</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126817006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187729008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93656003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93877002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93895004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:94119000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0014859</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153413</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153414</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153415</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153416</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0496775</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Ca lower third oesophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ca middle third oesophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">esophagus cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of distal third of esophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of lower third of oesophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of middle third of oesophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of proximal third of esophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of upper third esophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of Distal Third of esophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of Proximal Third of esophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of abdominal esophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of the middle Third of the esophagus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:5041</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#TopNodes_DOcancerslim"/>
        <rdfs:label xml:lang="en">esophageal cancer</rdfs:label>
        <skos:notation>DOID:5041</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_526 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_526">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:B20</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:042-042.99</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D015658</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3108</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:86406008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0019693</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">HIV infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:526</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">human immunodeficiency virus infectious disease</rdfs:label>
        <skos:notation>DOID:526</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_5295 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_5295">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_77"/>
        <obo:IAO_0000115 xml:lang="en">A gastrointestinal system disease that is located_in the intestine.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:10759</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:11222</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:11789</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8531</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8558</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8591</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:K63.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:569.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D007410</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C26801</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:266483008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0021831</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:5295</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">intestinal disease</rdfs:label>
        <skos:notation>DOID:5295</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_5409 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_5409">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3905"/>
        <obo:IAO_0000115 xml:lang="en">A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:0050875</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>KEGG:05222</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D055752</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:182280</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4917</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:254632001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0149925</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:5409</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">lung small cell carcinoma</rdfs:label>
        <skos:notation>DOID:5409</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_5517 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_5517">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_10534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_305"/>
        <obo:IAO_0000115 xml:lang="en">A stomach cancer that is located_in the stomach.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0000178</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4911</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154446008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0699791</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">cancer of the stomach</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">carcinoma of stomach</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">gastric carcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:5517</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">stomach carcinoma</rdfs:label>
        <skos:notation>DOID:5517</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_5520 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_5520">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_1542"/>
        <obo:IAO_0000115 xml:lang="en">A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:8503</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D000077195</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:275355</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34447</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:716659002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1168401</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">carcinoma of the head and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">squamous cell carcinoma of the head and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">squamous cell carcinomas of head and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:5520</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">head and neck squamous cell carcinoma</rdfs:label>
        <skos:notation>DOID:5520</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_574 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_574">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_863"/>
        <obo:IAO_0000115 xml:lang="en">A nervous system disease that affects the peripheral nervous system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:13069</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>NCI:C119734</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C27587</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0031117</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1335029</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">peripheral nerve disease</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">peripheral neuropathy</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:574</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">peripheral nervous system disease</rdfs:label>
        <skos:notation>DOID:574</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_635 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_635">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_526"/>
        <obo:IAO_0000115 xml:lang="en">A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0000765</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:B20</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D000163</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2851</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:62479008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0001175</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">AIDS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">acquired Immune deficiency</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">acquired immune deficiency syndrome</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:635</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">acquired immunodeficiency syndrome</rdfs:label>
        <skos:exactMatch>MESH:D000163</skos:exactMatch>
        <skos:notation>DOID:635</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_65 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_65">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_17"/>
        <obo:IAO_0000115 xml:lang="en">A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>MESH:D003240</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C26729</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:201432001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0009782</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">connective tissue disorder</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">disorder of connective tissue</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:65</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">connective tissue disease</rdfs:label>
        <skos:notation>DOID:65</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_6536 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_6536">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_707"/>
        <obo:IAO_0000115 xml:lang="en">A mature B-cell neoplasm that is composed of plasma cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0000200</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D010265</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:71390001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1136084</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Plasma cell dyscrasia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Plasma cell tumour</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Plasmacytic tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:6536</oboInOwl:id>
        <rdfs:label xml:lang="en">plasma cell neoplasm</rdfs:label>
        <skos:notation>DOID:6536</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_684 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_684">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_686"/>
        <obo:IAO_0000115 xml:lang="en">A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:5005</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>EFO:0000182</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C22.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:8170/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D006528</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:114550</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3099</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:88673</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154469006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C2239176</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Hepatoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:684</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">hepatocellular carcinoma</rdfs:label>
        <skos:notation>DOID:684</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_686 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_686">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_305"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
        <obo:IAO_0000115 xml:lang="en">A liver cancer that has_material_basis_in epithelial cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>NCI:C7927</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0279000</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Liver and Intrahepatic bile duct carcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:686</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">liver carcinoma</rdfs:label>
        <skos:notation>DOID:686</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_7 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_7">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4"/>
        <obo:IAO_0000115 xml:lang="en">A disease that manifests in a defined anatomical structure.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:5</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:71</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:72</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8</oboInOwl:hasAlternativeId>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:7</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <rdfs:label xml:lang="en">disease of anatomical entity</rdfs:label>
        <skos:notation>DOID:7</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_707 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_707">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:IAO_0000115 xml:lang="en">A non-Hodgkin lymphoma that has_material_basis_in B cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:5877</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D016393</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3457</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:109979007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0079731</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">B-cell lymphocytic neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:707</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">B-cell lymphoma</rdfs:label>
        <skos:notation>DOID:707</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_74 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_74">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">A disease of anatomical entity that has_material_basis_in hematopoietic cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:D75.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:289.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D006402</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C26323</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154785002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0018939</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Blood disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Blood dyscrasia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">DISEASE OF THE BLOOD AND BLOOD-FORMING ORGANS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Hematological disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">blood disorder</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">disease of haematopoietic system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">disease of hematopoietic system</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">haematopoietic system disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:74</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">hematopoietic system disease</rdfs:label>
        <skos:notation>DOID:74</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_7427 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_7427">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050338"/>
        <obo:IAO_0000115 xml:lang="en">A primary bacterial infectious disease that results_in infection located_in skin, located_in lung lymph nodes or located_in gastrointestinal tract, has_material_basis_in Bacillus anthracis, transmitted_by contact with infected animals or animal products, transmitted_by airborne spores or transmitted_by ingestion of undercooked meat from infected animals and has_symptom skin ulcer, has_symptom nausea, has_symptom poor appetite, has_symptom bloody diarrhea, has_symptom fever or has_symptom shortness of breath.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:8157</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A22</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:022</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D000881</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C84565</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154295005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0003175</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:7427</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#gram-positive_bacterial_infectious_disease"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">anthrax disease</rdfs:label>
        <skos:notation>DOID:7427</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_769 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_769">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_1192"/>
        <obo:IAO_0000115 xml:lang="en">An autonomic nervous system neoplasm that derives_from immature nerve cells.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0000621</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GARD:7185</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9500/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009447</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3270</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:635</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:432328008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0027819</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:769</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_childhood_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">Xref MGI. OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">neuroblastoma</rdfs:label>
        <skos:notation>DOID:769</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_77 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_77">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">A disease of anatomical entity that is located_in the gastrointestinal tract.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:27</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:944</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:K92.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:520-579.99</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D004066</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:53619000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0012242</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">GIT disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Gastroenteropathy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">alimentary system disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">digestive system disorder</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">gastrointestinal disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">gastrointestinal disorder</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:77</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <rdfs:label xml:lang="en">gastrointestinal system disease</rdfs:label>
        <skos:notation>DOID:77</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_8469 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_8469">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_1579"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results in infection, located in respiratory tract, has_material_basis_in Influenzavirus A (Alphainfluenzavirus), has_material_basis_in Influenzavirus B (Betainfluenzavirus), or has_material_basis_in Influenzavirus C (Gammainfluenzavirus), which are transmitted_by droplet spread of oronasal secretions during coughing, sneezing, or talking from an infected person. It is a highly contagious disease that affects birds and mammals and has_symptom chills, has_symptom fever, has_symptom sore throat, has_symptom runny nose, has_symptom muscle pains, has_symptom severe headache, has_symptom cough, and has_symptom weakness.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:8468</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:J11.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:487</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D007251</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C53482</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:155559006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0021400</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Influenza with other manifestations</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">flu</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">influenza with non-respiratory manifestation</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:8469</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">influenza</rdfs:label>
        <skos:notation>DOID:8469</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_848 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_848">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0080001"/>
        <obo:IAO_0000115 xml:lang="en">A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located_in joint.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:M19.90</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001168</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2883</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:372091005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0003864</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Inflammatory disorder of joint</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:848</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">arthritis</rdfs:label>
        <skos:exactMatch>MESH:D001168</skos:exactMatch>
        <skos:notation>DOID:848</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_850 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_850">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_1579"/>
        <obo:IAO_0000115 xml:lang="en">A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:11894</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:11895</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:29</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:766</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:J98.4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008171</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3198</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:266374002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0024115</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:850</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">Updating out dated CUI and removing lung abscess as a synonym.</rdfs:comment>
        <rdfs:label xml:lang="en">lung disease</rdfs:label>
        <skos:notation>DOID:850</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_8536 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_8536">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_863"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in infection located_in nerve fiber, has_material_basis_in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The virus is transmitted_by direct contact with the rash, which can develop into chickenpox in newly-infected individuals. The infection has_symptom rash which is followed by blisters, has_symptom headache, has_symptom fever, has_symptom malaise, has_symptom itching, has_symptom burning pain, and has_symptom paresthesia.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:8554</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8555</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8772</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8801</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9085</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:B02</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:053</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D006562</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C71079</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:186514003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0019360</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Shingles</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">herpes zona</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:8536</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">herpes zoster</rdfs:label>
        <skos:notation>DOID:8536</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_8557 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_8557">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0060119"/>
        <obo:IAO_0000115 xml:lang="en">A pharynx cancer that is located_in the oropharynx.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:8684</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8851</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8949</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9168</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:C10</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C10.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C10.3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C10.8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:146</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:146.5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:146.6</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:146.7</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C7398</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187686007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93933005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93971002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153382</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153388</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153389</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153390</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Oropharyngeal carcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant Oropharyngeal tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumor of oropharynx</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant tumour of mesopharynx</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">oropharyngeal cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:8557</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">oropharynx cancer</rdfs:label>
        <skos:notation>DOID:8557</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_8622 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_8622">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in infection located_in skin, has_material_basis_in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection has_symptom fever, has_symptom cough, has_symptom coryza, has_symptom conjunctivitis, and has_symptom maculopapular, erythematous rash.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:8621</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8963</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9112</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:3434</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:B05</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:055</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008457</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C96406</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154338006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0025007</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">morbilli</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:8622</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">measles</rdfs:label>
        <skos:notation>DOID:8622</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_863 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_863">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <obo:IAO_0000115 xml:lang="en">A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:G98</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:349.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009422</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C26835</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:155262005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0027765</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:863</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_GXD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_MGI_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">nervous system disease</rdfs:label>
        <skos:notation>DOID:863</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_8659 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_8659">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in infection located_in skin, has_material_basis_in Human herpesvirus 3, which is transmitted_by direct contact with secretions from the rash, or transmitted_by droplet spread of respiratory secretions. The infection has_symptom anorexia, has_symptom myalgia, has_symptom nausea, has_symptom fever, has_symptom headache, has_symptom sore throat, and has_symptom blisters.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:8658</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8693</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9243</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:B01.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:052</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002644</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C97132</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:186508005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0008049</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">varicella</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:8659</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">chickenpox</rdfs:label>
        <skos:exactMatch>MESH:D002644</skos:exactMatch>
        <skos:notation>DOID:8659</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_8736 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_8736">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_7"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results in infection located in skin, has_material_basis_in Variola virus (Orthopoxvirus variola), which is transmitted by droplets from oral, nasal or pharyngeal mucosa, transmitted by contact with the body fluids, or transmitted by fomites. The infection results in formation of lesions, first on the face, hands and forearms and later on the trunk.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:7444</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:B03</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:050</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012899</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C35027</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:266193008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0037354</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Ordinary smallpox</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:8736</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">smallpox</rdfs:label>
        <skos:notation>DOID:8736</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_874 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_874">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_104"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_850"/>
        <obo:IAO_0000115 xml:lang="en">A pneumonia involving inflammation of the lungs caused by bacteria.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:13815</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:J15.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:482.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D018410</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C26704</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:53084003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0004626</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Pneumonia due to other gram-negative bacteria</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">gram-negative pneumonia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:874</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#GOLD"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">bacterial pneumonia</rdfs:label>
        <skos:notation>DOID:874</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_8781 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_8781">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in infection located_in skin, has_material_basis_in Rubella virus (Rubivirus rubellae), which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection has_symptom rash on the face which spreads to the trunk and limbs, has_symptom fever, has_symptom lymphadenopathy, has_symptom joint pains, has_symptom headache, and has_symptom conjunctivitis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:11765</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1463</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:1464</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8780</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8816</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8909</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9106</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9116</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9162</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9179</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:4742</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:B06.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:056</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012409</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C85051</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:266192003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0035920</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">german measles</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:8781</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">rubella</rdfs:label>
        <skos:notation>DOID:8781</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_9210 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_9210">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results_in inflammation located_in facial nerve, which leads to paralysis of one side of the face, has_material_basis_in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The infection has_symptom vesicular rash of the ear or mouth, has_symptom tinnitus, has_symptom vertigo, has_symptom otalgia, and has_symptom headache.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:7525</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:B02.21</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:053.11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D016697</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C84763</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:21954000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0017409</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Geniculate herpes zoster</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Herpes zoster auricularis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Herpetic geniculate ganglionitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ramsay Hunt syndrome type 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ramsay Hunt syndrome type II</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Ramsey Hunt syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">geniculate neuralgia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">nervus intermedius neuralgia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:9210</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">herpes zoster oticus</rdfs:label>
        <skos:notation>DOID:9210</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_9256 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_9256">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_10155"/>
        <obo:IAO_0000115 xml:lang="en">A large intestine cancer that is located_in the colon and/or located_in the rectum.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>ICD10CM:C18.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:05210</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D015179</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:114500</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2956</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C4978</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:126837005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93854002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0009404</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0346629</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:9256</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_CFDE_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_RAD_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">Xref MGI. OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">colorectal cancer</rdfs:label>
        <skos:notation>DOID:9256</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_9261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_9261">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050615"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0060119"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_305"/>
        <obo:IAO_0000115 xml:lang="en">A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:8813</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:8814</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9057</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9144</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9197</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9229</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:7163</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C11.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C11.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C11.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C11.3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:147</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:147.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:147.1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:147.2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:147.3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009303</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:161550</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:607107</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C9321</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:150</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187692001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187693006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:187700006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:363398003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:93919005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:94078000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153392</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153393</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153394</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153395</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0153396</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0238301</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Nasopharyngeal carcinoma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant Nasopharyngeal tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">malignant neoplasm of nasopharynx</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">nasopharynx cancer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym xml:lang="en">carcinoma of nasopharynx</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>DOID:9261</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">Xref MGI. OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">nasopharynx carcinoma</rdfs:label>
        <skos:notation>DOID:9261</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_934 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_934">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050117"/>
        <obo:IAO_0000115 xml:lang="en">A disease by infectious agent that results in infection, has_material_basis_in Viruses.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:1329</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:A94</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:B34.9</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:060-066.99</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001102</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D014777</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3439</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C34396</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:34014006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:40610006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0003723</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0042769</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Viral Infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Viral disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">virus infection</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:934</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_AGR_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_FlyBase_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">viral infectious disease</rdfs:label>
        <skos:notation>DOID:934</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_9351 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_9351">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4"/>
        <obo:IAO_0000115 xml:lang="en">A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:0081062</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:E08-E13</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:250</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D003920</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C2985</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:267467004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0011849</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">diabetes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:9351</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">diabetes mellitus</rdfs:label>
        <skos:notation>DOID:9351</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_9470 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_9470">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_104"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_331"/>
        <obo:IAO_0000115 xml:lang="en">A meningitis that has_material_basis_in a bacterial infection.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>GARD:5881</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:G00</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:320</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D016920</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C118297</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:267680008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0085437</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:9470</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:label xml:lang="en">bacterial meningitis</rdfs:label>
        <skos:notation>DOID:9470</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_9538 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_9538">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4960"/>
        <obo:IAO_0000115 xml:lang="en">A myeloid neoplasm that is located_in the plasma cells in bone marrow.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasDbXref>EFO:0001378</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GARD:7108</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C90.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:203.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009101</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:254500</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3242</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:29073</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:94705007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0026764</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">myeloma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:9538</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <rdfs:label xml:lang="en">multiple myeloma</rdfs:label>
        <skos:notation>DOID:9538</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_9682 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/DOID_9682">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_934"/>
        <obo:IAO_0000115 xml:lang="en">A viral infectious disease that results in infection, has_material_basis_in Yellow fever virus (Orthoflavivirus flavi), which is transmitted by Aedes, transmitted by Haemagogus, or transmitted by Sabethes species of mosquitoes. The infection has symptom fever, has symptom muscle pain, has symptom backache, has symptom headache, has symptom shivers, has symptom loss of appetite, has symptom jaundice, and has symptom bleeding from the mouth, nose, eyes or stomach leading to vomitus containing blood.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/doid.owl"/>
        <oboInOwl:hasAlternativeId>DOID:9683</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:9684</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:7914</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:A95</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:060</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D015004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C35547</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2023_03_01:154345006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0043395</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">Sylvatic yellow fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Yellow fever, sylvan</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">jungle yellow fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">urban yellow fever</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>DOID:9682</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_infectious_disease_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#NCIthesaurus"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/doid#zoonotic_infectious_disease"/>
        <rdfs:label xml:lang="en">yellow fever</rdfs:label>
        <skos:notation>DOID:9682</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/FMA_12278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/FMA_12278">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/fma.owl"/>
        <oboInOwl:hasOBONamespace>fma</oboInOwl:hasOBONamespace>
        <oboInOwl:id>FMA:12278</oboInOwl:id>
        <rdfs:label>Hormone</rdfs:label>
        <skos:notation>FMA:12278</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0002250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002250">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0006955"/>
        <obo:IAO_0000115>An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:hasDbXref>Wikipedia:Adaptive_immune_system</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>acquired immune response</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>immune memory response</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>biological_process</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0002250</oboInOwl:id>
        <rdfs:label>adaptive immune response</rdfs:label>
        <skos:notation>GO:0002250</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0002385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0002385">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0006955"/>
        <obo:IAO_0000115>An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:hasAlternativeId>GO:0002386</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>GO:0002422</oboInOwl:hasAlternativeId>
        <oboInOwl:hasNarrowSynonym>immune response in MALT</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>immune response in mucosal-associated lymphoid tissue</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>immune response in urogenital tract</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>biological_process</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0002385</oboInOwl:id>
        <rdfs:label>mucosal immune response</rdfs:label>
        <skos:notation>GO:0002385</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0006955 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0006955">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0050896"/>
        <obo:IAO_0000115>Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:hasOBONamespace>biological_process</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0006955</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_drosophila"/>
        <rdfs:label>immune response</rdfs:label>
        <skos:notation>GO:0006955</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0008150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0008150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <obo:IAO_0000115>A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.</obo:IAO_0000115>
        <obo:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/24968</obo:IAO_0000233>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:created_by>jl</oboInOwl:created_by>
        <oboInOwl:creation_date>2012-09-19T15:05:24Z</oboInOwl:creation_date>
        <oboInOwl:hasAlternativeId>GO:0000004</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>GO:0007582</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>GO:0044699</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>Wikipedia:Biological_process</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>biological process</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>physiological process</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>biological_process</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>single organism process</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>single-organism process</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>GO:0008150</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_candida"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_chembl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_metagenomics"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_plant"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_pombe"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_yeast"/>
        <rdfs:comment>Note that, in addition to forming the root of the biological process ontology, this term is recommended for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code &apos;no data&apos; (ND), is used to indicate this.</rdfs:comment>
        <rdfs:label>biological_process</rdfs:label>
        <skos:notation>GO:0008150</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0019814 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0019814">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0032991"/>
        <obo:IAO_0000115>A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:hasNarrowSynonym>antibody</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0019814</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_pir"/>
        <rdfs:comment>Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.</rdfs:comment>
        <rdfs:label>immunoglobulin complex</rdfs:label>
        <skos:notation>GO:0019814</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0032991 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0032991">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <obo:IAO_0000115>A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:hasAlternativeId>GO:0043234</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>macromolecular complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>macromolecule complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>protein containing complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasNarrowSynonym>protein complex</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>protein-protein complex</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0032991</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_agr"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_chembl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_euk_cellular_processes_ribbon"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_flybase_ribbon"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_mouse"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_pir"/>
        <rdfs:comment>A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole.</rdfs:comment>
        <rdfs:label>protein-containing complex</rdfs:label>
        <skos:notation>GO:0032991</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0050896 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0050896">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
        <obo:IAO_0000115>Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:hasAlternativeId>GO:0051869</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>physiological response to stimulus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>biological_process</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0050896</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#gocheck_do_not_annotate"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_agr"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_flybase_ribbon"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_mouse"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_prokaryote"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_prokaryote_ribbon"/>
        <rdfs:comment>Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.</rdfs:comment>
        <rdfs:label>response to stimulus</rdfs:label>
        <skos:notation>GO:0050896</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0071735 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071735">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
        <obo:IAO_0000115>A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:created_by>mah</oboInOwl:created_by>
        <oboInOwl:creation_date>2010-03-24T01:44:53Z</oboInOwl:creation_date>
        <oboInOwl:hasNarrowSynonym>IgG1</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>IgG2</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>IgG2a</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>IgG2b</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>IgG2c</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>IgG3</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>IgG4</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0071735</oboInOwl:id>
        <rdfs:comment>Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species.</rdfs:comment>
        <rdfs:label>IgG immunoglobulin complex</rdfs:label>
        <skos:notation>GO:0071735</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0071738 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071738">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
        <obo:IAO_0000115>A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:created_by>mah</oboInOwl:created_by>
        <oboInOwl:creation_date>2010-03-24T01:44:53Z</oboInOwl:creation_date>
        <oboInOwl:hasOBONamespace>cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0071738</oboInOwl:id>
        <rdfs:comment>Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.</rdfs:comment>
        <rdfs:label>IgD immunoglobulin complex</rdfs:label>
        <skos:notation>GO:0071738</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0071742 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071742">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
        <obo:IAO_0000115>A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:created_by>mah</oboInOwl:created_by>
        <oboInOwl:creation_date>2010-03-24T01:44:53Z</oboInOwl:creation_date>
        <oboInOwl:hasOBONamespace>cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0071742</oboInOwl:id>
        <rdfs:comment>Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.</rdfs:comment>
        <rdfs:label>IgE immunoglobulin complex</rdfs:label>
        <skos:notation>GO:0071742</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0071745 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071745">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
        <obo:IAO_0000115>A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:created_by>mah</oboInOwl:created_by>
        <oboInOwl:creation_date>2010-03-24T01:44:53Z</oboInOwl:creation_date>
        <oboInOwl:hasNarrowSynonym>IgA1 antibody</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>IgA2 antibody</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0071745</oboInOwl:id>
        <rdfs:comment>Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.</rdfs:comment>
        <rdfs:label>IgA immunoglobulin complex</rdfs:label>
        <skos:notation>GO:0071745</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0071753 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0071753">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0019814"/>
        <obo:IAO_0000115>A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/go.owl"/>
        <oboInOwl:created_by>mah</oboInOwl:created_by>
        <oboInOwl:creation_date>2010-03-24T01:44:53Z</oboInOwl:creation_date>
        <oboInOwl:hasOBONamespace>cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:id>GO:0071753</oboInOwl:id>
        <rdfs:comment>Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.</rdfs:comment>
        <rdfs:label>IgM immunoglobulin complex</rdfs:label>
        <skos:notation>GO:0071753</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000001</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">conditional specification</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that specifies what should happen if the trigger condition is fulfilled.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">OBI_0000349</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">conditional specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000009"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000003</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">measurement unit label</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Examples of measurement unit labels are liters, inches, weight per volume.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: provenance: a term measurement unit was
proposed for OBI (OBI_0000176) , edited by Chris Stoeckert and
Cristian Cocos, and subsequently moved to IAO where the objective for
which the original term was defined was satisfied with the definition
of this, different, term.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: review of this term done during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">measurement unit label</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000005</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">objective specification</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: original definition when imported from OBI read: &quot;objective is an non realizable information entity which can serve as that  proper part of a plan towards which the realization of the plan is directed.&quot;</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2014-03-31: In the example of usage (&quot;In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction&quot;) there is a protocol which is the ChIP assay protocol. In addition to being concretized on paper, the protocol can be concretized as a realizable entity, such as a plan that inheres in a person. The objective specification is the part that says that some protein and DNA interactions are identified. This is a specification of a process endpoint: the boundary in the process before which they are not identified and after which they are. During the realization of the plan, the goal is to get to the point of having the interactions, and participants in the realization of the plan try to do that.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Answers the question, why did you do this experiment?</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Jennifer Fostel</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">goal specification</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">OBI Plan and Planned Process/Roles Branch</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">OBI_0000217</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">objective specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000007</metadata:prefixIRI>
        <obo:IAO_0000112 xml:lang="en">Pour the contents of flask 1 into flask 2</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that describes an action the bearer will take.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI Plan and Planned Process branch</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">action specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000009</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">datum label</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">http://www.golovchenko.org/cgi-bin/wnsearch?q=label#4n</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">GROUP: IAO</obo:IAO_0000117>
        <obo:IAO_0000232>9/22/11 BP: changed the rdfs:label for this class from &apos;label&apos; to &apos;datum label&apos; to convey that this class is not intended to cover all kinds of labels (stickers, radiolabels, etc.), and not even all kind of textual labels, but rather the kind of labels occuring in a datum. 
</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">datum label</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000088"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000311"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000013</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">journal article</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Examples are articles published in the journals, Nature and Science. The content can often be cited by reference to a paper based encoding, e.g.  Authors, Title of article, Journal name, date or year of publication, volume and page number.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A report that is published in a journal.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI_0000159</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">group:OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">journal article</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000027</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">data item</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Data items include counts of things, analyte concentrations, and statistical summaries.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym.</obo:IAO_0000116>
        <obo:IAO_0000116>2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">JAR: datum     -- well, this will be very tricky to define, but maybe some 
information-like stuff that might be put into a computer and that is 
meant, by someone, to denote and/or to be interpreted by some 
process... I would include lists, tables, sentences... I think I might 
defer to Barry, or to Brian Cantwell Smith

JAR: A data item is an approximately justified approximately true approximate belief</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Jonathan Rees</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">data</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">data item</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000030">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000031"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000030</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">information content entity</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Examples of information content entites include journal articles, data, graphical layouts, and graphs.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A generically dependent continuant that is about some thing.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2014-03-10: The use of &quot;thing&quot; is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ).</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">information_content_entity &apos;is_encoded_in&apos; some digital_entity in obi before split (040907). information_content_entity &apos;is_encoded_in&apos; some physical_document in obi before split (040907).

Previous. An information content entity is a non-realizable information entity that &apos;is encoded in&apos; some digital or physical entity.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI_0000142</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">information content entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000032">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000032</metadata:prefixIRI>
        <obo:IAO_0000112 xml:lang="en">10 feet. 3 ml.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: we decided to keep datum singular in scalar measurement datum, as in
this case we explicitly refer to the singular form</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Would write this as: has_part some &apos;measurement unit label&apos; and has_part some numeral and has_part exactly 2, except for the fact that this won&apos;t let us take advantage of OWL reasoning over the numbers. Instead use has measurment value property to represent the same. Use has measurement unit label (subproperty of has_part) so we can easily say that there is only one of them.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">scalar measurement datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000033</metadata:prefixIRI>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">An information content entity whose concretizations indicate to their bearer how to realize them in a process.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: provenance: a term realizable information entity was proposed for OBI (OBI_0000337) , edited by the PlanAndPlannedProcess branch. Original definition was  &quot;is the specification of a process that can be concretized and realized by an actor&quot; with alternative term  &quot;instruction&quot;.It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2013-05-30 Alan Ruttenberg: What differentiates a directive information entity from an information concretization is that it can have concretizations that are either qualities or realizable entities. The concretizations that are realizable entities are created when an individual chooses to take up the direction, i.e. has the intention to (try to) realize it.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">8/6/2009 Alan Ruttenberg: Changed label from &quot;information entity about a realizable&quot; after discussions at ICBO</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Werner pushed back on calling it realizable information entity as it isn&apos;t realizable. However this name isn&apos;t right either. An example would be a recipe. The realizable entity would be a plan, but the information entity isn&apos;t about the plan, it, once concretized, *is* the plan. -Alan</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">directive information entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000064">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000064</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">algorithm</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PMID: 18378114.Genomics. 2008 Mar 28. LINKGEN: A new algorithm to process data in genetic linkage studies.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI_0000270</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">adapted from discussion on OBI list (Matthew Pocock, Christian Cocos, Alan Ruttenberg)</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">algorithm</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000078 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000078">
        <owl:equivalentClass>
            <owl:Class>
                <owl:oneOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000002"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000120"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000121"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000122"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000123"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000124"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000125"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000423"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000428"/>
                </owl:oneOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000078</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">curation status specification</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON:Bill Bug</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP:OBI:&lt;http://purl.obolibrary.org/obo/obi&gt;</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">OBI_0000266</obo:IAO_0000119>
        <rdfs:label xml:lang="en">curation status specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000088 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000088">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000088</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">report</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Examples of reports are gene lists and investigation reports. These are not published (journal) articles but may be included in a journal article.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">A document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record).</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: comment from Darren Natale: I am slightly uneasy with the sentence &quot;Topic of the report is on 
something that has completed.&quot;  Should it be restricted to those things 
that are completed?  For example, a progress report is (usually) about 
something that definitely has *not* been completed, or may include 
(only) projections.  I think the definition would not suffer if the 
whole sentence is deleted.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: this was report of results with definition: A report is a narrative object that is a formal statement of the results of an investigation, or of any matter on which definite information is required, made by some person or body instructed or required to do so.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2009-08-10 Alan Ruttenberg: Larry Hunter suggests that this be obsoleted and replaced by &apos;document&apos;. Alan restored as there are OBI dependencies and this merits further discussion</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">disagreement about where reports go. alan: only some gene lists are reports. Is a report all the content of some document? The example of usage suggests that a report may be part of  some article. Term needs clarification</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">GROUP: OBI</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">OBI_0000099</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">report</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000100</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">data set</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Intensity values in a CEL file or from multiple CEL files comprise a data set (as opposed to the CEL files themselves).</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2009/10/23 Alan Ruttenberg. The intention is that this term represent collections of like data. So this isn&apos;t for, e.g. the whole contents of a cel file, which includes parameters, metadata etc. This is more like java arrays of a certain rather specific type</obo:IAO_0000116>
        <obo:IAO_0000116>2014-05-05: Data sets are aggregates and thus must include two or more data items. We have chosen not to add logical axioms to make this restriction.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">person:Allyson Lister</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI_0000042</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">group:OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">data set</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000102 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000102">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000102</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">data about an ontology part</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Data about an ontology part is a data item about a part of an ontology, for example a term</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">data about an ontology part</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000104">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000104</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">plan specification</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PMID: 18323827.Nat Med. 2008 Mar;14(3):226.New plan proposed to help resolve conflicting medical advice.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2009-03-16: provenance: a term a plan was proposed for OBI (OBI_0000344) , edited by the PlanAndPlannedProcess branch. Original definition was &quot; a plan is a specification of a process that is realized by an actor to achieve the objective specified as part of the plan&quot;. It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2014-03-31: A plan specification can have other parts, such as conditional specifications.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">2022-01-16 Updated definition to that proposed by Clint Dowloand, IAO Issue 231.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Alternative previous definition: a plan is a set of instructions that specify how an objective should be achieved</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Clint Dowland</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI Plan and Planned Process branch</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">OBI_0000344</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:comment xml:lang="en">2/3/2009 Comment from OBI review.

Action specification not well enough specified.
Conditional specification not well enough specified.
Question whether all plan specifications have objective specifications.

Request that IAO either clarify these or change definitions not to use them</rdfs:comment>
        <rdfs:label xml:lang="en">plan specification</rdfs:label>
        <rdfs:seeAlso xml:lang="en">https://github.com/information-artifact-ontology/IAO/issues/231#issuecomment-1010455131</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000109 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000109">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000109</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">measurement datum</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Examples of measurement data are the recoding of the weight of a mouse as {40,mass,&quot;grams&quot;}, the recording of an observation of the behavior of the mouse {,process,&quot;agitated&quot;}, the recording of the expression level of a gene as measured through the process of microarray experiment {3.4,luminosity,}.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2/2/2009 is_specified_output of some assay?</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">person:Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI_0000305</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">group:OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">measurement datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000225 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000225">
        <owl:equivalentClass>
            <owl:Class>
                <owl:oneOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000103"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000226"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000227"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000228"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000229"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OMO_0001000"/>
                </owl:oneOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000225</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">obsolescence reason specification</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">The creation of this class has been inspired in part by Werner Ceusters&apos; paper, Applying evolutionary terminology auditing to the Gene Ontology.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
        <rdfs:label xml:lang="en">obsolescence reason specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000310">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000310</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">document</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">A journal article, patent application, laboratory notebook, or a book</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A collection of information content entities intended to be understood together as a whole</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON: Lawrence Hunter</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">document</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000311 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000311">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000311</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">publication</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">journal article, newspaper story, book, etc.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A document that is the output of a publishing process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON: Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Lawrence Hunter</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">published document</obo:IAO_0000118>
        <obo:IAO_0000233 rdf:resource="https://github.com/information-artifact-ontology/IAO/issues/232"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:comment xml:lang="en">Revisit the term in Octorber 2020. Improve the defintion.</rdfs:comment>
        <rdfs:label xml:lang="en">publication</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000409 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000409">
        <owl:equivalentClass>
            <owl:Class>
                <owl:oneOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000410"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000420"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000421"/>
                </owl:oneOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0000409</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">denotator type</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are &quot;natural kinds&quot; and the latter arbitrary collections of entities.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A denotator type indicates how a term should be interpreted from an ontological perspective.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Barry Smith, Werner Ceusters</obo:IAO_0000119>
        <rdfs:label xml:lang="en">denotator type</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0020000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0020000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:0020000</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">identifier</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Justin Whorton</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Mathias Brochhausen</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">proper name</obo:IAO_0000118>
        <obo:IAO_0000233 xml:lang="en">https://github.com/information-artifact-ontology/IAO/issues/237</obo:IAO_0000233>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <dc:creator>Mathias Brochhausen</dc:creator>
        <rdfs:comment xml:lang="en">Sep 29, 2016: The current definition has been amended from the previous version: &quot;A proper name is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity.&quot; to more accuratly reflect the necessary and sufficient condition on the class. (MB)</rdfs:comment>
        <rdfs:label xml:lang="en">identifier</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000102"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000000</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">ontology module</obo:IAO_0000111>
        <obo:IAO_0000116 xml:lang="en">I have placed this under &apos;data about an ontology part&apos;, but this can be discussed. I think this is OK if &apos;part&apos; is interpreted reflexively, as an ontology module is the whole ontology rather than part of it.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">ontology file</obo:IAO_0000118>
        <obo:IAO_0000232 xml:lang="en">This class and it&apos;s subclasses are applied to OWL ontologies. Using an rdf:type triple will result in problems with OWL-DL. I propose that dcterms:type is instead used to connect an ontology URI with a class from this hierarchy. The class hierarchy is not disjoint, so multiple assertions can be made about a single ontology.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000001</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">base ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">base ontology module</rdfs:label>
        <rdfs:seeAlso rdf:resource="https://github.com/INCATools/ontology-starter-kit/issues/50"/>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000002</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">editors ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users.</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">source ontology module</obo:IAO_0000118>
        <rdfs:label xml:lang="en">editors ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000003</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">main release ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An ontology module that is intended to be the primary release product and the one consumed by the majority of tools.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">TODO: Add logical axioms that state that a main release ontology module is derived from (directly or indirectly) an editors module</obo:IAO_0000116>
        <rdfs:label xml:lang="en">main release ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000004</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">bridge ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">bridge ontology module</rdfs:label>
        <rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/inter-anatomy-ontology-bridge-ontologies"/>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000005</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">import ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A subset ontology module that is intended to be imported from another ontology.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">TODO: add axioms that indicate this is the output of a module extraction process.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">import file</obo:IAO_0000118>
        <rdfs:label xml:lang="en">import ontology module</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/extract"/>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000006</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">subset ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms.</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">ontology slim</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">subset ontology</obo:IAO_0000118>
        <rdfs:label xml:lang="en">subset ontology module</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/filter"/>
        <rdfs:seeAlso rdf:resource="http://www.geneontology.org/page/go-slim-and-subset-guide"/>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000007</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">curation subset ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">curation subset ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000008">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000008</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">analysis ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An ontology module that is intended for usage in analysis or discovery applications.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">analysis subset ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000009</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">single layer ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint.</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">ribbon subset</obo:IAO_0000118>
        <rdfs:label xml:lang="en">single layer subset ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000010">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000010</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">exclusion subset ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes.</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">antislim</obo:IAO_0000118>
        <rdfs:label xml:lang="en">exclusion subset ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000011</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">external import ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach.</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">external import</obo:IAO_0000118>
        <rdfs:label xml:lang="en">external import ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000012">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000012</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">species subset ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A subset ontology that is crafted to either include or exclude a taxonomic grouping of species.</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">taxon subset</obo:IAO_0000118>
        <rdfs:label xml:lang="en">species subset ontology module</rdfs:label>
        <rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000013</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">reasoned ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">reasoned ontology module</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/reason"/>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000014</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">generated ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">TODO: Add axioms (using PROV-O?) that indicate this is the output-of some reasoning process</obo:IAO_0000116>
        <rdfs:label xml:lang="en">generated ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000015">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000014"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000015</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">template generated ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">An ontology module that is automatically generated from a template specification and fillers for slots in that template.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">template generated ontology module</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://robot.obolibrary.org/template"/>
        <rdfs:seeAlso rdf:resource="https://doi.org/10.1186/s13326-017-0126-0"/>
        <rdfs:seeAlso rdf:resource="https://github.com/dosumis/dead_simple_owl_design_patterns/"/>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000004"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000016</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">taxonomic bridge ontology module</obo:IAO_0000111>
        <rdfs:label xml:lang="en">taxonomic bridge ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000006"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000017</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">ontology module subsetted by expressivity</obo:IAO_0000111>
        <rdfs:label xml:lang="en">ontology module subsetted by expressivity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000017"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000018</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">obo basic subset ontology module</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.

Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).

An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports</obo:IAO_0000115>
        <rdfs:label xml:lang="en">obo basic subset ontology module</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://owlcollab.github.io/oboformat/doc/obo-syntax.html#6.2"/>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000017"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000019</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">ontology module subsetted by OWL profile</obo:IAO_0000111>
        <rdfs:label xml:lang="en">ontology module subsetted by OWL profile</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IAO_8000020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_8000020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_8000019"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IAO:8000020</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">EL++ ontology module</obo:IAO_0000111>
        <rdfs:label xml:lang="en">EL++ ontology module</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IDO_0000403 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000403">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IDO:0000403</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">A symbiont role borne by an organism in virtue of the fact that it derives a growth, survival, or fitness advantage from symbiosis while the other symbiont&apos;s growth, survival, or fitness is reduced.</obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
        <rdfs:comment>In the medical community, the term &apos;parasite&apos; is used with the narrower meaning of eukaryotic pathogen.</rdfs:comment>
        <rdfs:comment>The role is realized in processes that result in the parasite&apos;s growth, survival, or fitness advantage or in the other organism&apos;s growth, survival, or fitness reduction.</rdfs:comment>
        <rdfs:label xml:lang="en">parasite role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IDO_0000409 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000409">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000725"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IDO:0000409</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis reaches developmental maturity or reproduces sexually in the host.  </obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">primary host role</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
        <rdfs:comment>The role is realized in developmental and reproduction processes of the host&apos;s partner in symbiosis.</rdfs:comment>
        <rdfs:label xml:lang="en">definitive host role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IDO_0000418 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000418">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IDO:0000418</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">An infectious agent transporter role that is borne by an organism active in the transfer of an infectious agent to an organism of another Species and in which the agent is infectious.</obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
        <rdfs:comment>The role is realized in a transmission process.  A bearer of a vector role is also a bearer of a host role.</rdfs:comment>
        <rdfs:label xml:lang="en">infectious agent vector role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IDO_0000420 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000420">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IDO_0000418"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IDO:0000420</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">An infectious agent vector role borne by an organism in virtue of the fact that the infectious agent multiplies in the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
        <rdfs:label xml:lang="en">biological vector of infectious agent role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IDO_0000450 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000450">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IDO:0000450</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">A disposition to initiate processes that result in a disorder.</obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">pathogenicity</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
        <rdfs:comment>A pathogenic disposition is realized in processes that create a disorder.</rdfs:comment>
        <rdfs:comment>The use of &apos;initiates&apos; is intended to convey that a pathogenic disposition is realized when processes resulting in a disorder begin because of some action on the part of the bearer of the disposition.  By this interpretation of &apos;initiates&apos;, disorder-causing entities such as glass, UV light, and toxins do not have a pathogenic disposition.</rdfs:comment>
        <rdfs:label xml:lang="en">pathogenic disposition</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IDO_0000528 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000528">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IDO:0000528</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">A material entity with a pathogenic disposition.</obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
        <rdfs:label xml:lang="en">pathogen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IDO_0000547 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000547">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IDO:0000547</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">A biological macromolecule produced by a pathogen and that has a virulence factor disposition.</obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
        <rdfs:label xml:lang="en">virulence factor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/IDO_0000586 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IDO_0000586">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IDO:0000586</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population.</obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ido.owl"/>
        <rdfs:comment>The organism corresponding to the extended organism is host to the infectious agents.  By this definition, parts of the host can be considered part of the infection.</rdfs:comment>
        <rdfs:label xml:lang="en">infection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0005065 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0005065">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_14566"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MONDO:0005065</metadata:prefixIRI>
        <obo:IAO_0000115>A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mondo.owl"/>
        <rdfs:label>mesothelioma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0005194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0005194">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_0050117"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MONDO:0005194</metadata:prefixIRI>
        <obo:IAO_0000115>Infection with any of the rotaviruses. Specific infections include human infantile diarrhea, neonatal calf diarrhea, and epidemic diarrhea of infant mice.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mondo.owl"/>
        <rdfs:label>Rotavirus infection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0023644 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0023644">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_1542"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MONDO:0023644</metadata:prefixIRI>
        <obo:IAO_0000115>A carcinoma arising in the lip or oral cavity. Most oral cavity carcinomas are squamous cell carcinomas of the tongue, buccal mucosa, or gums. Less frequent morphologic variants include mucoepidermoid carcinoma and adenocarcinoma. Lip carcinomas are usually basal cell or squamous cell carcinomas.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/mondo.owl"/>
        <rdfs:label>lip and oral cavity carcinoma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10090 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10090">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39107"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10090</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:85055</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>house mouse</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>mouse</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mus musculus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10114 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10114">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39107"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10114</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>rat</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>rats</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rattus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10141 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10141">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33550"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10141</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:84274</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>domestic guinea pig</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>guinea pig</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Cavia aperea porcellus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Cavia cobaya</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mus porcellus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Cavia porcellus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33550"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10150</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chinchillas</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chinchillas and viscachas</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Chinchillidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10239 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10239">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10239</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superkingdom"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Vira</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Viridae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>viruses</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Viruses</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10240 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10240">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732525"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10240</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Poxviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10240"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10241</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Chordopoxvirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10241"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10242</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthopoxvirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10242"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10244</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:130669</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:130670</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>MPXV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>monkey pox virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>mpox</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>mpox virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Monkeypox virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10245">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10242"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10245</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>vaccinia virus VV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Vaccinia virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10242"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10255</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12871</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>small pox virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>smallpox</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>smallpox virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>variola virus VAR</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Variola virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10258 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10258">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10241"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10258</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Contagious pustular dermatitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orf virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10260 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10260">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10241"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10260</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Avipoxvirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10261">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10260"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10261</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>FWPV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avipoxvirus clade A1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Fowlpoxvirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>fowl poxvirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>fowlpox virus FP</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>fowlpox virus FPV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Fowlpox virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10264 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10264">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10260"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10264</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Pigeon pox virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Pigeon poxvirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>pigeonpox virus PPV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Pigeonpox virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_102793 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_102793">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:102793</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avian influenza virus H5N1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>H5N1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>H5N1 subtype</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10292">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_548681"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10292</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Herpesviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10293 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10293">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3044472"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10293</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Alphaherpesviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Alphaherpesvirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10294 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10294">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10293"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10294</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Simplexvirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10298 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10298">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10294"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10298</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>HSV-1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>HSV1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Herpes simplex virus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human herpesvirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>herpes simplex virus 1 HSV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>herpes simplex virus HSV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>herpes simplex virus type 1 HSV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>herpes simplex virus type 1 HSV1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>herpes simplex virus type-1 HSV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Herpes simplex virus 1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Human herpesvirus 1</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Human alphaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10310">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10294"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10310</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>HSV2</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Herpes simplex virus (type 2)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Herpes simplex virus II</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Herpes simplex virus type 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Herpes simplex virus type 2 (HSV-2)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human herpesvirus 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Herpes simplex virus 2</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>herpes simplex virus type 2 HSV-2</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Human alphaherpesvirus 2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10293"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10319</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Varicellovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10320">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10319"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10320</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11265</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:12738</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>BoHV-1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Bovine herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine herpesvirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine herpesvirus-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine rhinotracheitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine herpesvirus 1 BHV 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine herpesvirus 1 BHV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine herpesvirus 1 BHV1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine herpesvirus BHV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine herpesvirus type 1 BHV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine herpesvirus type-1 BHV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>infectious bovine rhinotracheitis virus BHV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Infectious bovine rhinotracheitis virus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>bovine alphaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10326 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10326">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10319"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10326</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>EHV-1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Equid herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Equine herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Equine herpesvirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Equine herpesvirus-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>equine abortion virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>equine herpesvirus 1 EHV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>equine herpesvirus type-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>equine herpesvirus type 1 EHV-1</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Equid alphaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10334">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10319"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10334</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Felid herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Feline alphaherpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Feline herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Feline herpesvirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>feline herpesvirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>feline herpesvirus type 1 FHV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>feline herpesvirus-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>feline herpesvirus-1 FHV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Felid alphaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10335 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10335">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10319"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10335</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>HHV-3</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>VZV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human herpes virus 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human herpesvirus 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Varicella Zoster Virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Varicella-zoster virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>varicella zoster virus VZV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>varicella-zoster virus VZV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Human alphaherpesvirus 3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10345 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10345">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10319"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10345</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:44156</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>PRV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Alphaherpesvirus pseudorabies virus PRV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Aujeszky&apos;s disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Pseudorabies Virus PRV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Pseudorabies virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Suid herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Suid herpesvirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Suid alphaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10357 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10357">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3044472"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10357</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Betaherpesviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Betaherpesvirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10358 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10358">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10358</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Cytomegalovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10359">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10358"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10359</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>HHV-5</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human cytomegalovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human herpesvirus 5</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>human herpesvirus type 5</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Human betaherpesvirus 5</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10366 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10366">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10366</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Mouse cytomegalovirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Murid herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Murine cytomegalovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>murine cytomegalovirus (MCMV)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>murine cytomegalovirus MCMV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>murine herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Murid betaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10386">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_180255"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10386</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:10342</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:12743</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:46620</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>GaHV-1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>ILTV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avian infectious laryngotracheitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Gallid herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Gallid herpesvirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Laryngotracheitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>infectious laryngotracheitis virus ILTV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Infectious laryngotracheitis virus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Gallid alphaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10390 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10390">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_180252"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10390</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:38013</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:39111</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:43684</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>GaHV-2</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>MDV1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Gallid herpesvirus 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Gallid herpesvirus type 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek disease virus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek&apos;s disease herpesvirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek&apos;s disease herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek&apos;s disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek&apos;s disease virus (MDV)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek&apos;s disease virus MDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek&apos;s disease virus MDV1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek&apos;s disease virus serotype 1 MDV-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Marek&apos;s disease virus type 1 MDV1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Mareks disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Marek&apos;s disease virus type 1</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Gallid alphaherpesvirus 2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10405 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10405">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732514"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10405</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>mammalian hepatitis B-type viruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthohepadnavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10407 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10407">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10405"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10407</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>HBV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human hepatitis B virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hepatitis B virus (HBV)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hepatitis B virus HBV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hepatitis B virus, HBV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>human hepatitis B virus HBV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Hepatitis B virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_104388 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_104388">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_180252"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:104388</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:72150</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Anatid Herpes virus-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Anatid herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Duck enteritis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Duck plague virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>anatid alphaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10469 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10469">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10469</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Baculovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Baculovirus sp.</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>unidentified baculovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10497 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10497">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732525"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10497</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>ASFV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>African swine fever virus ASF</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>African swine fever virus ASFV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>African swine fever virus, ASFV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>African swine fever virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10508 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10508">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10508</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Adenoviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10509 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10509">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10508"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10509</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mastadenovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10512 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10512">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10537"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10512</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12607</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Canine adenovirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Canine adenovirus type 1 Cav-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Mastadenovirus c1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Mastadenovirus can1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>canine adenovirus type 1 Can1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>dog adenovirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canine adenovirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10514 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10514">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10537"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10514</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Canine adenovirus type 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Canine adenovirus type 2 Cav-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Mastadenovirus c2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Mastadenovirus can2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>dog adenovirus 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canine adenovirus 2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10535 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10535">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10509"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10535</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Adenovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>unidentified adenovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10537 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10537">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10509"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10537</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Canine adenovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Canine adenovirus A</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canine mastadenovirus A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10566 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10566">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_333774"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10566</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human Papilloma Virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>human papillomavirus HPV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Human papillomavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10571 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10571">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_333774"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10571</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bovine papillomavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_107819 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_107819">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1502"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:107819</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Clostridium perfringens (type D)</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Clostridium perfringens D</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10786 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10786">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052707"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10786</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>FPLV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Feline panleucopenia virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Feline panleukopaenia virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Feline panleukopenia virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10787 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10787">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10786"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10787</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Feline panleukopenia virus (strain 193)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10788 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10788">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052707"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10788</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>CPV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canine parvovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10792 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10792">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10786"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10792</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>MEV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mink enteritis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10796 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10796">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1506574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10796</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>PPV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>porcine parvovirus PPV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Porcine parvovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10892 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10892">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2946186"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10892</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Orbiviridae</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Orbiviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orbivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10912 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10912">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2946186"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10912</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Rotaviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rotavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10913 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10913">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10913</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Porcine rotavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10927 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10927">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10927</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>bovine rotavirus BRV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bovine rotavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10937 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10937">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10937</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Equine rotavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10993 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10993">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732396"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10993</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Birnaviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_10995 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10995">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10993"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:10995</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12740</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>IBDV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avian infectious bursal disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Gumboro virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Infectious bursal disease virus of chickens</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>infectious bursal disease virus IBDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Infectious bursal disease virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10993"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11002</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12744</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>IPNV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>infectious pancreatic necrosis virus IPNV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Infectious pancreatic necrosis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732461"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11019</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Alphaviridae</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>arboviruses group A</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Alphavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11021">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11019"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11021</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Eastern equine encephalomyelitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>eastern equine encephalomyelitis EEE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>eastern equine encephalomyelitis virus EEEV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Eastern equine encephalitis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11019"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11034</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Sindbis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11019"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11036</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>VEE</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>VEEV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Venezuelan equine encephalitis VEE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Venezuelan equine encephalitis virus VEE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Venezuelan equine encephalomyelitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Venezuelan equine encephalitis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11039 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11039">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11019"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11039</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Western equine encephalomyelitis virus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Western equine encephalitis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732543"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11040</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rubivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11041">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11041</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rubella virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_76803"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11047</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>EAV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Equine arteritis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732406"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11050</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Flavivirus (arbovirus group B)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Flaviviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11050"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11051</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>arboviruses group B</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Flavivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11072 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11072">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3044782"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11072</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Japanese encephalitis (JE) virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Japanese encephalitis virus JE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Japanese encephalitis virus JEV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Japanese encephalitis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11082 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11082">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3044782"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11082</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>WNV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>West Nile virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11084 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11084">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3044782"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11084</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>TBEV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>FSME virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Tick born encephalitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>tick-borne encephalitis virus TBE virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>tick-borne encephalitis virus TBEV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Tick-borne encephalitis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11089 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11089">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3044782"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11089</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>YFV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Flavivirus febricis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>yellow fever virus YFV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Yellow fever virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11095 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11095">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11050"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11095</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12832207</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7747470</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Pestivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11096">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11095"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11096</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12625</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:54314</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7747470</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Hog cholera virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Pestivirus type 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>classical swine fever virus CSFV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>swine fever virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Classical swine fever virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11099">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11095"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11099</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:121864</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>BVDV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>BVDV-1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7747470</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Bovine viral diarrhea virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine viral diarrhea virus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine viral diarrhea virus-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Mucosal disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Pestivirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine viral diarrhea virus BVDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine viral diarrhea virus type I</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bovine viral diarrhea virus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_111105 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_111105">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_836"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:111105</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11411686</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:28066339</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Porphyromonas gulae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11118 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11118">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_76804"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11118</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Coronaviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2501931"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11120</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>IBV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avian infectious bronchitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>avian infectious bronchitis coronavirus IBV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>avian infectious bronchitis virus IBV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>avian infectious bronchitis virus, IBV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>infectious bronchitis virus IBV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Infectious bronchitis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11128 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11128">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_694002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11128</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>BCV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>BECV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Bovine enteritic coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine enteritic coronavirus BECV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine coronavirus BCV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine enteric coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>calf diarrheal coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>neonatal calf diarrhea virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bovine coronavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11135 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11135">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_693997"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11135</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>FIPV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Feline infectious peritonitis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11149 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11149">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_693997"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11149</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12859</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>TGEV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Porcine transmissable gastroenteritis coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Porcine transmissible gastroenteritis coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>porcine transmissible gastroenteritis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>transmissible gastroenteritis coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>transmissible gastroenteritis virus TGEV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Transmissible gastroenteritis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11153 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11153">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_693997"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11153</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Canine enteric coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>canine coronavirus CCV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canine coronavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11157 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11157">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2497569"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11157</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>negative-sense genome single-stranded RNA viruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mononegavirales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11158 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11158">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11157"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11158</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Paramyxoviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11216 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11216">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186938"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11216</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11202</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>HPIV-3</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>HPIV3</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human parainfluenza 3 virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human parainfluenza virus 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human parainfluenza virus type 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Parainfluenza virus type 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>human parainfluenza virus 3 HPIV3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>human parainfluenza virus type 3 PIV3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>parainfluenza virus type 3 PIV-3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>human parainfluenza virus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Human respirovirus 3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11229">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560076"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11229</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Morbilliviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Morbillivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11234">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11229"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11234</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11230</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Cell-associated subacute sclerosing panencephalitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Measles virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Subacute sclerosing panencephalitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>measles virus MV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>rougeole virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>rubeola virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>subacute sclerose panencephalitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>subacute sclerosing panencephalitis virus, SSPEV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Measles morbillivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11229"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11241</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>RDV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Rinderpest virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>rinderpest virus RPV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>rinderpest virus RV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rinderpest morbillivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11157"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11244</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Pneumovirinae</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Pneumoviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11246 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11246">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1868215"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11246</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12604</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>BRS</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>BRSV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>bovine RSV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine respiratory syncytial virus BRSV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bovine orthopneumovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11250">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1868215"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11250</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>HRSV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human orthopneumovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>human RSV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>human respiratory syncytial virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11266 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11266">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11157"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11266</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11267</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Filovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Filoviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11270 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11270">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11157"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11270</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16186241</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rhabdoviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11286 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11286">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11270"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11286</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Lyssavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11287 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11287">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186778"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11287</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12873</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:12874</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>VHSV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Haemorrhagic septicemia virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Hemorrhagic septicemia virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Viral haemorrhagic septicaemia virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hemorragic septicemy virus of fish</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>viral haemorrhagic scepticaemia virus VHS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>viral haemorrhagic septicaemia virus VHSV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>viral hemorrhagic septicemia virus VHSV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Viral hemorrhagic septicemia virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11290 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11290">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186778"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11290</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>IHNV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Infectious hematopoietic necrosis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11292">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11286"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11292</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Rabies lyssavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Rabies virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Lyssavirus rabies</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11308 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11308">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2497571"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11308</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthomyxoviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11309 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11309">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_35324"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11309</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Influenza virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Influenza virus sp.</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Influenzavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>avian influenza virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>unidentified influenza virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11318 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11318">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11318</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Dhori thogotovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Dhori virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Tick-borne virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Thogotovirus dhoriense</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11320">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197911"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11320</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>FLUAV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human Influenza A Virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Influenza virus type A</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>influenza A virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Influenza A virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_114727 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_114727">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:114727</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>H1N1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>H1N1 subtype</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11520 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11520">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11520</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>FLUBV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Influenza virus type B</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Influenza B virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11588 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11588">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980410"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11588</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>RVFV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rift Valley fever virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11636 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11636">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_153135"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11636</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11835</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:11872</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:36380</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avian reticuloendotheliosis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>reticuloendotheliosis virus A REV-A</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>reticuloendotheliosis virus REV-A</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Reticuloendotheliosis virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11646 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11646">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_327045"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11646</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Lentivirinae</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Lentivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11673 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11673">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11646"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11673</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>FIV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>feline immunodeficiency virus FIV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Feline immunodeficiency virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11723 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11723">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11646"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11723</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11677</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:11739</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:11740</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>CIV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>SIV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Chimpanzee immunodeficiency virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Chimpanzee immunodeficiency virus (SIV(CPZ))</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Simian immunodeficiency virus SIVcpz</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>simian immunodeficiency virus SIV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>simian immunodeficiency virus, SIV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>simian immunodeficiency viruses SIV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Simian immunodeficiency virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_117565 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_117565">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7742"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:117565</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>fish</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>fishes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Agnatha</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Hyperotreti</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Myxini</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_117571 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_117571">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7742"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:117571</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:40673</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>bony vertebrates</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Euteleostomi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11768 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11768">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_153135"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11768</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11920</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Feline leukemia provirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>feline leukemia virus FeLV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Feline leukemia virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11901 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11901">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_327045"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11901</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>BLV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>bovine leukemia virus BLV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine leukemia virus, BLV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bovine leukemia virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_119088 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_119088">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1206794"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:119088</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Enoplea</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_119210 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_119210">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:119210</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>H3N2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>H3N2 subtype</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11974 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11974">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_464095"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11974</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Caliciviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11976 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11976">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11974"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11976</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12806</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:31701</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>RHDV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Rabbit haemorrhagic disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>rabbit hemorrhagic disease virus RHDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rabbit hemorrhagic disease virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_11978 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_11978">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11974"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:11978</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>FCV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Feline vesivirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>feline calicivirus FCV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Feline calicivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12058 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12058">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_464095"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12058</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Picornavirus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Picornaviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12059 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12059">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12058"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12059</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12128</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Enteroviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Enterovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12066">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12059"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12066</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Coxsackievirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1206794 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1206794">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33317"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1206794</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Ecdysozoa</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12080</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasBroadSynonym>HPV-1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>PV1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human poliovirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human poliovirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Polio virus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Poliovirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>poliovirus type 1 PV1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Poliovirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12083 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12083">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12083</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasBroadSynonym>HPV-2</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human Poliovirus type 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human poliovirus 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Poliovirus type 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Poliovirus 2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12086 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12086">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12086</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasBroadSynonym>HPV-3</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human poliovirus 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human poliovirus type 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Polio virus 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Poliovirus serotype 3</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Poliovirus type 3</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Poliovirus 3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12091 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12091">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2946633"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12091</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Hepatovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12092 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12092">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12091"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12092</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>HAV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Hepatitis A virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Hepatovirus A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12110 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12110">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12058"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12110</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>FMDV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Foot and mouth disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>foot and mouth disease virus FMDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>foot-and-mouth disease virus FMDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Foot-and-mouth disease virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1224">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3379134"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1224</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_phylum"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11321122</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11837318</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>purple photosynthetic bacteria and relatives</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>&quot;Alphaproteobacteriota&quot; Whitman et al. 2018</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Alphaproteobacteriota</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Proteobacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Proteobacteriota</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>proteobacteria</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Pseudomonadota</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12264 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12264">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_464095"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12264</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>CPMV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Cowpea mosaic virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1236">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1224"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1236</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23334881</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Proteobacteria gamma subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pseudomonadia</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Purple bacteria, gamma subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>g-proteobacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gamma proteobacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gamma subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gamma subgroup</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Gammaproteobacteria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1238 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1238">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_72273"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1238</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1371057</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Piscirickettsia salmonis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1239 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1239">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1783272"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1239</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_phylum"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10555317</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11034484</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11542017</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15143038</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25403554</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:37409558</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:38376502</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>low G+C Gram-positive bacteria</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>low GC Gram+</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillaeota</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillota corrig. Gibbons and Murray 2021</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus/Clostridium group</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Clostridium group firmicutes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Low G+C firmicutes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>clostridial firmicutes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>firmicutes</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bacillota</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12455 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12455">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11157"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12455</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>BDV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25449305</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Borna disease virus BDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Borna disease virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12475 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12475">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12475</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12682</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>HDV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Hepatitis D virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hepatitis delta virus HDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Hepatitis delta virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12618 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12618">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12618</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>CAV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Chicken infectious anemia virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chicken anaemia agent CAA</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chicken anemia virus CAV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chicken anemia virus, CAV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>chicken anaemia agent virus CAA</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Chicken anemia virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12637 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12637">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3044782"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12637</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Dengue virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12721 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12721">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11646"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12721</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>HIV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>AIDS virus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Human immunodeficiency virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1279 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1279">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1385"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1279</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319469</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319495</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10425778</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10758876</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12656157</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17220435</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9734063</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Aurococcus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Staphylococcus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1280">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1279"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1280</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:325213</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:46170</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:72759</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31023808</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8573498</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Micrococcus aureus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Micrococcus pyogenes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Staphlococcus pyogenes citreus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Staphylococcus aureus subsp. anaerobius</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Staphylococcus pyogenes aureus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Staphylococcus aureus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12814 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12814">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12814</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>RSV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>respiratory syncytial virus RS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>respiratory syncytial virus RS virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>respiratory syncytial virus RSV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Respiratory syncytial virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_12845 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_12845">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_35324"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:12845</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Swine influenza virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1301 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1301">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91061"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1301</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10555340</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:14657115</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1720654</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19620365</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19880633</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7537076</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8995803</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Streptococcus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1307 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1307">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1301"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1307</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23245487</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:5220563</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9731300</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9734065</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Streptococcus suis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1311 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1311">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1301"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1311</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:76757</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15774692</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8995807</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Streptoccocus de la mammite</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Streptococcus agalactiae contagiosae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Streptococcus difficile</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Streptococcus difficilis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Streptococcus mastitidis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Streptococcus agalactiae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1313 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1313">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1301"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1313</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Diplococcus pneumoniae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Micrococcus pneumoniae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Streptococcus pneumoniae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1314 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1314">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1301"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1314</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Micrococcus scarlatinae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Streptococcus erysipelatos</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Streptococcus hemolyticus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Streptococcus scarlatinae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Streptococcus pyogenes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1335626 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1335626">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_694002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1335626</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>MERS</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>MERS-CoV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>MERS coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>MERS virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Middle East Respiratory Syndrome Coronavirus (MERS-CoV)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Middle East respiratory syndrome coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Middle East respiratory syndrome-related coronavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1336 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1336">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1301"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1336</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Streptococcus equi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_13488 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_13488">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1489388"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:13488</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Dicentrarchus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_13489 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_13489">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_13488"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:13489</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>European sea bass</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>European seabass</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Labrax labrax</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Morone labrax</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Perca labrax</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Roccus labrax</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Sciaena labrax</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Dicentrarchus labrax</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_136 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_136">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_203692"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:136</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11075904</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11542017</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16558735</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1917844</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23908650</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>spirochetes</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Spirochaetales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1385">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91061"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1385</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:2954866</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:30896383</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus/Staphylococcus group</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Caryophanales</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bacillales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1386">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1385"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1386</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10843090</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11491334</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1742196</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2223602</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23475340</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7727277</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8138135</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8863420</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Bacillus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bacillus rRNA group 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bacillus &lt;firmicutes&gt;</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_138950 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_138950">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12059"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:138950</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:138953</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Enterovirus EV-C</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human enterovirus C</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Poliovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Enterovirus C</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_139 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_139">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_64895"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:139</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1380285</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1503971</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24744012</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7699027</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7981102</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8995796</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9336916</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Lyme disease spirochete</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Borrelia burgdorferi</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Borreliella burgdorferi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1392 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1392">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1386"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1392</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1494525</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1494531</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1494577</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8123566</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>anthrax</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>anthrax bacterium</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus cereus var. anthracis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacteridium anthracis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bacillus anthracis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1437010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1437010">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40674"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1437010</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11743200</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11791233</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Boreotheria</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Boreoeutheria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1485 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1485">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1485</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:69207</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:26643615</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27488356</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Anaerobacter</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Anaerobacter Duda et al. 1996</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Clostridium</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1489388 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1489388">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186625"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1489388</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_cohort"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Euteleosteomorpha</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1491 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1491">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1485"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1491</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:29368</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10028279</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15244052</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus botulinus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus putrificus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Botulobacillus botulinus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Clostridium putrificum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Ermengemillus botulinus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pacinia putrifica</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Clostridium botulinum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_149539 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_149539">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_59201"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:149539</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1245786</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2588446</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2588447</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:41533</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:592</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10758910</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Salmonella enterica serovar Enteritidis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus enteritidis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enteritidis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Salmonella enterica subsp. enterica serovar Enteritidis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_149595 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_149595">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11158"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:149595</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canine parainfluenza virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_150052 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_150052">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_629"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:150052</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subspecies"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11043982</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Yersinia enterocolitica subsp. enterocolitica</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1502 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1502">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1485"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1502</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1683536</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3298488</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1374625</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:184898</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacterium welchii</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Clostridium perfringens (Veillon and Zuber 1898) Hauduroy et al. 1937 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Clostridium plagarum</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Clostridium perfringens</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1506574 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1506574">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40119"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1506574</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:10781</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Parvovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Parvoviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Protoparvovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1513 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1513">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1485"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1513</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus tetani</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Clostridium tetani</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_151340 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_151340">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732421"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:151340</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:20206957</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Papillomavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Papillomaviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_151341 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_151341">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732421"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:151341</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Polyomaviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_153135 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_153135">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_327045"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:153135</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11762</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>MLV-related viruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Mammalian type C retrovirus group</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Mammalian type C retroviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>mammalian type C oncoviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>type C oncoviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Gammaretrovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1549675 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1549675">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8825"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1549675</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superorder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Galloanseri</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Galloanserae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_160 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_160">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:160</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Microspironema pallidum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spirillum pallidum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spirochaeta pallida</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spironema pallidum</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Treponema pallidum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_162145 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_162145">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162387"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:162145</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>HMPV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>human metapneumovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_162387 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_162387">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11244"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:162387</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Metapneumovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1639 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1639">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1385"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1639</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1634566</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293539</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293540</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293541</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293542</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293543</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293544</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293545</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293546</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293547</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364651</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364652</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364653</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364654</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364655</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364656</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364657</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364658</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364659</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2364660</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482733</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482734</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482735</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482736</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482737</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482738</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482739</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482740</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482741</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482742</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482743</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482744</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482745</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482746</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482747</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482748</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2482749</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2484857</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2484858</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485082</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485083</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485084</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485085</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485086</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485087</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485088</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485089</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485090</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485091</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485092</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485093</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485094</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485095</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2485096</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486732</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486733</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486734</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486735</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486736</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486737</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486738</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486739</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486740</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2486741</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17773427</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1906732</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8782698</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacterium monocytogenes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium monocytogenes hominis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Corynebacterium infantisepticum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Corynebacterium parvulum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Erysipelothrix monocytogenes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Listerella hepatolytica</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Listeria monocytogenes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1648 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1648">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1648</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1503975</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8427802</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus insidiosus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus rhusiopathiae suis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium rhusiopathiae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Erysipelothrix erysipeloides</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Erysipelothrix insidiosa</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Erysipelothrix murisepticus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Erysipelothrix porci</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Erysipelothrix rhusiopathiae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1649845 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1649845">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_629"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1649845</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon#_species_group"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Yersinia pseudotuberculosis complex</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1653394 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1653394">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980410"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1653394</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mammarenavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1678143 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1678143">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732543"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1678143</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12461</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2953663</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Orthohepevirus A</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Paslahepevirus balayani</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_169418 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_169418">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3072906"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:169418</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mustelinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_171 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_171">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_203692"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:171</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:29512</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:29514</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:29516</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10425768</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1581182</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19868121</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9103653</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Leptospira</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1716 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1716">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85007"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1716</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:144193</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10425754</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19661509</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:29760685</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:30186281</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7547284</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7547291</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7547293</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8186090</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Turicella</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Corynebacterium</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1717 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1717">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1716"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1717</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7729671</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus diphtheriae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium diphtheriae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Microsporon diphthericum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Microsporon diphtheriticum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium diphtheriae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pacinia loeffleri</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Corynebacterium diphtheriae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1719 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1719">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1716"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1719</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus pseudotuberculosis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus pseudotuberculosis-ovis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Corynebacterium ovis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Corynebacterium preisz-nocardi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Corynebacterium pseudotuberculosis-ovis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium tuberculosis-ovis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Corynebacterium pseudotuberculosis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_173 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_173">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:173</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:2843297</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2843299</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15545494</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19867994</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19868337</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19972157</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25288661</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9542090</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Leptospira icteroides</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spirochaeta biflexa</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spirochaeta icterogenes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spirochaeta icterohaemorrhagiae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spirochaeta interrogans</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spirochaeta nodosa</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Leptospira interrogans</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_175121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_175121">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3073809"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:175121</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Passeroidea</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_176 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_176">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_173"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:176</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Leptospira hardjo</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Leptospira interrogans serovar Hardjo</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1763 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1763">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85007"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1763</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1380284</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1581193</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16014496</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1883713</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2275850</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31296783</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31649146</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31649147</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:34554081</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7547284</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7547304</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7907223</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8863452</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mycobacterium Lehmann and Neumann 1896 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycobacterium</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1764 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1764">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1763"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1764</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2397193</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8347508</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus tuberculosis gallinarum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium tuberculosis avium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium tuberculosis typus gallinaceus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Tuberculose des oiseaux</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycobacterium avium</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1765 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1765">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1765</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_biotype"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:115863</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10618079</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11931153</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:14657105</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:29205127</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mycobacterium bovis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium tuberculosis typus bovinus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium tuberculosis var. bovis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycobacterium tuberculosis variant bovis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1769 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1769">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1763"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1769</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus leprae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycobacterium leprae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1773 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1773">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1763"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1773</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:2528440</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:29205127</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus tuberculosis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium tuberculosis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium tuberculosis (Zopf 1883) Lehmann and Neumann 1896 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium tuberculosis typus humanus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium tuberculosis var. hominis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycobacterium tuberculosis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1781 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1781">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1763"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1781</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12089250</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:20668542</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:38415640</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mycobacterium balnei</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium platypoecilus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycobacterium marinum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1783272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1783272">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1783272</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_kingdom"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:31968</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3376104</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18988685</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Terrabacteria group</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Firmacutes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Firmicuteota</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Firmicutes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Firmicutes corrig. Gibbons and Murray 1978 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Terrabacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Terrabacterida</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bacillati</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_180252 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_180252">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10293"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:180252</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Marek&apos;s disease-like viruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mardivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_180255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_180255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10293"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:180255</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Infectious laryngo-tracheitis-like viruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Infectious laryngotracheitis-like viruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Iltovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_186537 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_186537">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11266"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:186537</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Marburg-like viruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Marburgvirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_186625 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_186625">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7898"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:186625</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Clupeocephala</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_186778 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_186778">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11270"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:186778</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Novirhabdovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1868215 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1868215">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11244"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1868215</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthopneumovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_186938 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_186938">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11158"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:186938</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Respirovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1891747 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1891747">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_151341"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1891747</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:10625</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>BFPyV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Aves polyomavirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>BFDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Budgerigar fledgling disease polyomavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Budgerigar fledgling disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Budgerigar fledgling polyomavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Gammapolyomavirus avis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1903411 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1903411">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91347"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1903411</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27620848</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Yersiniaceae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_194">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_213849"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:194</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11542086</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12361288</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16627635</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1704793</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19801389</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:29034857</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:38530055</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Campylobacter</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_196 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_196">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_194"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:196</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11321120</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1354478</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Spirillum fetus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio fetus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Campylobacter fetus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_197 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_197">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_194"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:197</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:2172531</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2182326</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2201165</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2211407</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2211408</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2211409</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293848</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293849</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2293850</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2303571</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2305452</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2305453</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2305454</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2305455</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2305456</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2305457</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2305458</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2305459</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2340789</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2478524</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2572055</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2572062</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2572070</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2572072</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2572075</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2572080</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2572086</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2870880</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2870881</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2893406</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2916035</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2916036</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2939732</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2950109</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042472</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042475</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042476</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042477</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042478</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042479</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042480</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042481</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042482</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042483</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042484</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042485</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042486</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3042488</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3109033</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3109035</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3109036</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3109054</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3109055</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:3231045</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11321120</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Campylobacter fetus subsp. jejuni</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio hepaticus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio jejuni</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Campylobacter jejuni</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_197911 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_197911">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:197911</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Influenzavirus A</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Alphainfluenzavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_197912 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_197912">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:197912</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Influenzavirus B</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Betainfluenzavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_197913 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_197913">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:197913</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Influenzavirus C</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Gammainfluenzavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1980410 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1980410">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2497571"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1980410</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bunyavirales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1980442 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1980442">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980410"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1980442</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11598</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Hantavirus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Orthohantavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_1980915 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_1980915">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186778"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:1980915</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:38142</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>HIRRV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Hirame novirhabdovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Hirame rhabdovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Novirhabdovirus hirame</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superkingdom"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10425795</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10425796</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10425797</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10490293</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10843050</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10939651</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10939673</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10939677</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11211268</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11321083</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11321113</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11411719</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11540071</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11542017</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11542087</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11760965</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12054223</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:270744</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:32628106</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:36748408</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7520741</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8123559</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8186100</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8590690</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9103655</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9336922</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>eubacteria</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacteria (ex Cavalier-Smith 1987)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacteria Woese et al. 2024</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacteriobiota</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Monera</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Procaryotae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Prokaryota</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Prokaryotae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>bacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>prokaryote</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>prokaryotes</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bacteria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_200644 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_200644">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_976"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:200644</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Flavobacteriales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_203692 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_203692">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3379134"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:203692</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11837318</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25288668</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:26654112</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Spirochaetes</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Spirochaetia</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_204722 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_204722">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:204722</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12271122</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella suis str. 1330</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Brucella melitensis biovar Suis str. 1330</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Brucella suis ATCC 23444</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Brucella suis NCTC 10316</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Brucella suis 1330</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_205488 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_205488">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11266"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:205488</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11268</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Ebola virus EBO</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>unidentified Ebola virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Ebola virus sp.</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_206351 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_206351">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28216"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:206351</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23575986</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Neisseriales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2093">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_544448"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2093</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:29500</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:57371</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10826816</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11321109</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11411711</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11931184</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13403276</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15176735</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16350067</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16403858</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25288662</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8863441</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8995799</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Asterococcus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Asteromyces</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Borrelomyces</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bovimyces</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Eperythrozoon</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haemobartonella</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pleuropneumonia</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycoplasma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2096">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2790996"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2096</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:4</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mycoplasma gallisepticum</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycoplasmoides gallisepticum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2099">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2895623"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2099</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11491338</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1316139</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1374621</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8573513</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mycoplasma hyopneumoniae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycoplasma suipneumoniae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mesomycoplasma hyopneumoniae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_210 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_210">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_213849"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:210</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:219</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11931154</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1995031</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8186097</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8494747</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Campylobacter pylori</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Campylobacter pylori subsp. pylori</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Campylobacter pyloridis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Helicobacter nemestrinae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Helicobacter pylori</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2109 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2109">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2895623"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2109</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:4</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mycoplasma synoviae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycoplasmopsis synoviae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_211880 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_211880">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_173"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:211880</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Leptospira canicola</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Leptospira interrogans serovar Canicola</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_213849 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_213849">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3379134"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:213849</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16403855</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Campylobacterales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2157 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2157">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2157</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superkingdom"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10425795</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10425796</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10425797</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10490293</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10843050</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10939651</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10939673</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10939677</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11211268</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11321083</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11321113</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11411719</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11540071</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11541975</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11542064</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11542149</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11760965</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12054223</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25527841</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:270744</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:32628106</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:36748408</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8123559</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8590690</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9103655</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9336922</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Archaebacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Archaebiota</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mendosicutes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Metabacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Monera</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Procaryotae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Prokaryota</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Prokaryotae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>archaea</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>prokaryote</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>prokaryotes</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Archaea</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2169991 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2169991">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1653394"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2169991</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11619</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Argentinian mammarenavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Junin arenavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Junin mammarenavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Junin virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Junn mammarenavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mammarenavirus juninense</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_224914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_224914">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:224914</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11756688</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Brucella melitensis ATCC 23456</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Brucella melitensis bv. 1 str. 16M</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_234">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28211"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:234</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:28066370</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:32373076</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:35335701</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:37395662</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8573514</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Brucella</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_235 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_235">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:235</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella melitensis bv. Abortus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacterium abortus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Brucella melitensis biovar Abortus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Brucella abortus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_236">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:236</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella melitensis bv. Ovis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Brucella melitensis biovar Ovis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Brucella ovis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2497569 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2497569">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732396"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2497569</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_phylum"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Negative-strand RNA viruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Negarnaviricota</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2497571 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2497571">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2497569"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2497571</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subphylum"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Polyploviricotina</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2501931 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2501931">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2501931</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthocoronavirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2559587 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2559587">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2559587</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>RNA viruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>RNA viruses and viroids</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Riboviria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2560069 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2560069">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11158"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2560069</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Avulavirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2560076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2560076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11158"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2560076</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthoparamyxovirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2560080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2560080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11158"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2560080</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rubulavirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2560319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2560319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560069"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2560319</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11176</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>NDV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avian Paramyxovirus Serotype I</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Avian avulavirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Avian orthoavulavirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Avian paramyxovirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Avian paramyxovirus type-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Newcastle disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Newcastle disease virus NDV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>avian paramyxovirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2560602 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2560602">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560080"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2560602</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11161</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1979165</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Mumps virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mumps rubulavirus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mumps orthorubulavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_260963 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_260963">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560069"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:260963</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Avulavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_260964 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_260964">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560076"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:260964</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Henipavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2611341 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2611341">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2611341</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:30257078</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Metamonada</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2611352 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2611352">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2611352</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Discoba</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_262698 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_262698">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:262698</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15805518</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella abortus biovar 1 str. 9-941</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Brucella abortus bv. 1 strain 9-941</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Brucella abortus bv. 1 str. 9-941</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_263 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_263">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_72273"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:263</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacterium tularense</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Brucella tularensis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Francisella tularense</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pasteurella tularensis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Francisella tularensis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2697049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2697049">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_694009"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2697049</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>SARS-CoV-2</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>2019-nCoV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>COVID-19 virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>HCoV-19</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Human coronavirus 2019</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>SARS-2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>SARS-CoV2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>SARS2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Severe acute respiratory syndrome coronavirus 2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732005</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_kingdom"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bamfordvirae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732092 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732092">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732092</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_kingdom"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Shotokuvirae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732396 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732396">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2559587"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732396</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_kingdom"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthornavirae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732406 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732406">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732396"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732406</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_phylum"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Tombus-Noda-like virus sp.</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Kitrinoviricota</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732415 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732415">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732092"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732415</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_phylum"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Cossaviricota</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732421 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732421">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732415"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732421</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Papovaviricetes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732461 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732461">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732406"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732461</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Alsuviricetes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732506 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732506">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732396"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732506</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Pisoniviricetes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732514 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732514">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2559587"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732514</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Revtraviricetes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732525 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732525">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732525</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Pokkesviricetes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732541 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732541">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732396"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732541</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:10880</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Reoviridae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Reovirales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2732543 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2732543">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732461"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2732543</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Hepelivirales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2759 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2759">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2759</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superkingdom"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23020233</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:30257078</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>eucaryotes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>eukaryotes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Eucarya</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Eucaryotae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Eukarya</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Eukaryotae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>eukaryotes</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Eukaryota</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_27592 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_27592">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9895"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:27592</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bovinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2790996 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2790996">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_544448"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2790996</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31385780</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31971499</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:35947640</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mycoplasmoidales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_28115 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_28115">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_836"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:28115</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:29525</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1503973</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacteroides macacae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacteroides melaninogenicus subsp. macacae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacteroides salivosus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Porphyromonas salivosa</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Porphyromonas macacae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_28174 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_28174">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_641"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:28174</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:707</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Listonella ordalii</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Vibrio ordalii</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_28211 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_28211">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1224"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:28211</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11541974</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11837318</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16166687</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16403855</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19060069</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Alphabacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Proteobacteria alpha subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Purple bacteria, alpha subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>a-proteobacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>alpha proteobacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>alpha subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>alpha subgroup</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Alphaproteobacteria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_28216 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_28216">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1224"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:28216</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16403855</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:28581923</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Proteobacteria beta subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Purple bacteria, beta subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>b-proteobacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>beta proteobacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>beta subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>beta subgroup</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Betaproteobacteria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_28344 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_28344">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_76803"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:28344</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12796</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:70172</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>PRRSV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Porcine reproductive and respiratory syndrome virus (PRRSV)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Porcine respiratory and reproductive syndrome virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>porcine reproductive and respiratory syndrome virus PRRSV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>porcine reproductive and respiratory syndrome virus, PRRSV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Porcine reproductive and respiratory syndrome virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_28450 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_28450">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_80840"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:28450</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1435366</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1435368</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1435988</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1439853</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1487954</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1487955</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12734250</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1283774</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus pseudomallei</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium whitmori</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Loefflerella pseudomallei</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Malleomyces pseudomallei</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pseudomonas pseudomallei</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Burkholderia pseudomallei</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_286 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_286">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1236"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:286</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:212745</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10758879</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10939664</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15950132</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18048745</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7727274</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9103607</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>RNA similarity group I</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>&quot;Chlorobacterium&quot; Guillebeau 1890, nom. rejic. Opin. 6 (not &quot;Chlorobacterium&quot; Lauterborn 1916)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Chryseomonas</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Flavimonas</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Liquidomonas</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Loefflerella</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pseudomonas Migula 1894 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Serpens</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Serpens Hespell 1977 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Pseudomonas</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_287 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_287">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_286"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:287</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1224290</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1437768</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1437769</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1437770</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1508364</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1607811</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1607813</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1683559</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1683561</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1851858</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1851865</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1860124</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2952935</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:665948</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:912077</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:931955</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:931956</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:931957</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:931958</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:932477</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus aeruginosus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus pyocyaneus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium aeruginosum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium pyocyaneum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Micrococcus pyocyaneus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pseudomonas aeruginosa (Schroeter 1872) Migula 1900 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pseudomonas polycolor</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pseudomonas pyocyanea</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>probable synonym or variety: &quot;Pseudomonas polycolor&quot; Clara 1930</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Pseudomonas aeruginosa</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2871093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2871093">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2871093</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>avian encephalomyelitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>tremovirus A1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2895623 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2895623">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2790996"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2895623</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31385780</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31971499</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:35947640</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Metamycoplasmataceae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2901879 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2901879">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_694009"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2901879</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>SARS-CoV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>SARS coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>SARS virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Severe acute respiratory syndrome coronavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_29176 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_29176">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5809"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:29176</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Neospora caninum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_29459 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_29459">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:29459</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8573514</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Micrococcus melitensis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Streptococcus Miletensis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Brucella melitensis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_29461 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_29461">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:29461</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella melitensis bv. Suis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Brucella melitensis biovar Suis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Brucella suis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2946186 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2946186">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732541"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2946186</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:689832</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Sedoreovirinae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Sedoreoviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_2946633 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2946633">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12058"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:2946633</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Heptrevirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_29486 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_29486">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_629"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:29486</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Yersinia ruckeri</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_29546 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_29546">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3379134"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:29546</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7547305</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7857801</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7981108</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8123559</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8347512</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9226893</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Candidatus intracellularis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Ileal symbiont intracellularis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Lawsonia intracellularis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3044472 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3044472">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_548681"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3044472</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthoherpesviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3044782 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3044782">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11050"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3044782</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthoflavivirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3052223 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052223">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_260964"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3052223</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:45337</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:63330</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7701348</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Equine morbillivirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Hendra henipavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Hendra virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Henipavirus hendraense</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3052225 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052225">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_260964"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3052225</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:121791</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Nipah henipavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Nipah virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Nipah-virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Henipavirus nipahense</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3052230 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052230">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11050"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3052230</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11103</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>HCV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Hepacivirus C</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Hepatitis C virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hepatitis C virus HCV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>human hepatitis C virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>human hepatitis C virus HCV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>human hepatitis virus C HCV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>post-transfusion hepatitis non A non B virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Hepacivirus hominis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3052303 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052303">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1653394"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3052303</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11623</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:12748</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>LCMV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Lymphocytic choriomeningitis mammarenavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Lymphocytic choriomeningitis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>lymphocytic choriomeningitis virus LCMV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mammarenavirus choriomeningitidis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3052310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052310">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1653394"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3052310</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11620</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Lassa mammarenavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Lassa virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Mammarenavirus lassaense</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3052342 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052342">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11229"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3052342</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11232</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Canine morbillivirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Morbillivirus canis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3052518 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052518">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980410"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3052518</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11593</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1980519</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>CCHFV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Crimean-Congo haemorrhagic fever virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Crimean-Congo hemorrhagic fever nairovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Crimean-Congo hemorrhagic fever orthonairovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Crimean-Congo hemorrhagic virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Crimean-Congo hemorrhagic fever virus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Orthonairovirus haemorrhagiae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3052707 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052707">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1506574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3052707</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1511906</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Carnivore protoparvovirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Protoparvovirus carnivoran 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Protoparvovirus carnivoran1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3052729 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3052729">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186938"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3052729</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:11215</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Bovine parainfluenza 3 virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine parainfluenza virus 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine parainfluenza virus type 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine respirovirus 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Respirovirus bovis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3072906 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3072906">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_379584"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3072906</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Musteloidea</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3073809 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3073809">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8825"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3073809</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Australaves</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_314145 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_314145">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1437010"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:314145</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superorder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11214318</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11214319</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12878460</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Laurasiatheria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_314146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_314146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1437010"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:314146</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superorder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11214319</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12082125</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12878460</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15522813</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Euarchontoglires</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_314147 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_314147">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314146"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:314147</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11214319</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12082125</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15522813</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Rodents and rabbits</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Glires</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_314293 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_314293">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9443"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:314293</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_infraorder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Anthropoidea</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Simiiformes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_32524 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_32524">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117571"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:32524</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>amniotes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Amniota</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_32561 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_32561">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_32524"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:32561</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>diapsids</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Diapsida</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Sauria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_327045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_327045">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732514"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:327045</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Orthoretrovirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_329639 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_329639">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40119"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:329639</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:186155</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Canine parvovirus-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Minute virus of canines</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canine minute virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_33154 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33154">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:33154</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Fungi/Metazoa group</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>opisthokonts</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Opisthokonta</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_33213 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33213">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33154"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:33213</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bilateria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_33317 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33317">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33213"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:33317</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Protostomia</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_33340 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33340">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1206794"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:33340</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_infraclass"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Neoptera</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_333774 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_333774">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_151340"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:333774</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>unclassified Papillomaviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3344809 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3344809">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10294"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3344809</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Herpes Simplexvirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_33550 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33550">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9989"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:33550</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_suborder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>guinea pigs and others</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Hystricognathi</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Hystricomorpha</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_33554 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33554">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314145"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:33554</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>carnivores</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>carnivores</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Carnivora</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_3379134 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_3379134">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:3379134</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_kingdom"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Pseudomonadati</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_33892 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_33892">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:33892</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>BCG</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mycobacterium bovis BCG</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>bacillus Calmette-Guerin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>bacillus Calmette-Guerin BCG</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycobacterium tuberculosis variant bovis BCG</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_34085 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_34085">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_200644"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:34085</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13200095</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22427448</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8240957</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9103649</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Moraxella anatipestifer</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pasteurella anapestifer</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pasteurella anatipestifer</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pfeifferella anatipestifer</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Riemerella anatipestifer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_353210 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_353210">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_153135"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:353210</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Replication competent viruses</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_35324 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_35324">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:35324</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>unclassified Orthomyxoviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_35500 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_35500">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91561"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:35500</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_infraorder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Pecora</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_359391 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_359391">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:359391</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16299333</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:20462421</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Brucella melitensis biovar Abortus 2308</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Brucella abortus 2308</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_36362 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_36362">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_151341"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:36362</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:10624</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Polyomavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Polyomaviruses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Polyomavirus sp.</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_36420 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_36420">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:36420</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>H1N1 swine influenza virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_36470 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_36470">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1301"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:36470</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Streptococcus sp. (group A)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>group A streptococci</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>group A streptococcus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Streptococcus sp. &apos;group A&apos;</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_36855 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_36855">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:36855</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella melitensis bv. Canis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Brucella melitensis biovar Canis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Brucella canis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_37124 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_37124">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11019"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:37124</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Chikungunya virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_379584 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_379584">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33554"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:379584</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_suborder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Caniformia</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_38170 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_38170">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732541"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:38170</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avian reovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Avian orthoreovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_38345 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_38345">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:38345</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1581182</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Leptospira grippotyphosa</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Leptospira kirschneri serovar Grippotyphosa</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_38525 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_38525">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162387"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:38525</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avian pneumovirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>avian metapneumovirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_38568 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_38568">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5658"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:38568</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subgenus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Leishmania</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Leishmania &lt;subgenus&gt;</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_38574 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_38574">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38568"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:38574</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon#_species_group"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Leishmania donovani species complex</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_39107 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_39107">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9989"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:39107</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:109679</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Murinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_391902 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_391902">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_27592"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:391902</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subspecies"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bos bubalis bubalis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bubalus bubalis bubalis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_393305 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_393305">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:393305</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Yersinia enterocolitica subsp. enterocolitica str. 8081</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Yersinia enterocolitica subsp. enterocolitica strain 8081</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Yersinia enterocolitica subsp. enterocolitica 8081</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_39744 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_39744">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560080"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:39744</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rubulavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_39944 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_39944">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10319"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:39944</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>CpHV-1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Caprine herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Caprine herpesvirus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>goat herpesvirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Caprine alphaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_40050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_40050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10892"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:40050</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:10896</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>AHSV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>African horse sickness group</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>African horse sickness virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>African horse sickness virus (AHSV)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>African horsesickness virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>African horse sickness virus AHSV</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Orbivirus alphaequi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_40051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_40051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10892"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:40051</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:12591</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Bluetongue virus group</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bluetongue virus BTV</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bluetongue virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_400570 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_400570">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10260"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:400570</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Quailpox virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_40119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_40119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732415"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:40119</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Parvovirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_40269 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_40269">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_641"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:40269</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18048732</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Vibrio salmonicida</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Aliivibrio salmonicida</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_40674 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_40674">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_32524"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:40674</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>mammals</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>mammals</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mammalia</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_41678 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_41678">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10508"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:41678</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasBroadSynonym>TAdV-3</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Marble spleen disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Turkey adenovirus serotype 3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Turkey haemorrhagic enteritis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Turkey hemorrhagic enteritis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hemorrhagic enteritis virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Turkey adenovirus 3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_418101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_418101">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:418101</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subgenus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Vinckeia</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Plasmodium (Vinckeia)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_418103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_418103">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:418103</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subgenus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Plasmodium</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Plasmodium (Plasmodium)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_422676 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_422676">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5794"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:422676</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Hematozoa Vivier 1982</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Aconoidasida</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_423054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_423054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5794"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:423054</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_suborder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Eimeriorina</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_42890 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_42890">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5809"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:42890</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Sarcocystis neurona</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_430066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_430066">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:430066</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella abortus str. S19</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Brucella abortus strain S19</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Brucella abortus S19</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_44088 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_44088">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10260"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:44088</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasBroadSynonym>CNPV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Avipoxvirus clade B1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Canary poxvirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canarypox virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_444163 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_444163">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:444163</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:399128</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18218934</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Brucella microti</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_444178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_444178">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_236"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:444178</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella ovis str. ATCC 25840</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Brucella ovis strain ATCC 25840</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Brucella ovis ATCC 25840</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_452646 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_452646">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_169418"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:452646</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:9667</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>American mink</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>mink</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mustela vison</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Neovison vison</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Neogale vison</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_464095 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_464095">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732506"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:464095</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Picornavirales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_470137 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_470137">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:470137</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19346311</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella suis str. ATCC 23445</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Brucella suis strain ATCC 23445</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Brucella suis ATCC 23445</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_4751 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_4751">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33154"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:4751</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_kingdom"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11062127</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12684019</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mycota</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>fungi</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Fungi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_476 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_476">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1236"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:476</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Haemophilus bovis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Moraxella (subgen. Moraxella Lwoff 1939) bovis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Moraxella duplex des bovids</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Moraxella bovis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_483179 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_483179">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_36855"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:483179</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19346311</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella canis str. ATCC 23365</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Brucella canis strain ATCC 23365</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Brucella canis ATCC 23365</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_487 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_487">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_206351"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:487</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Diplokokkus intracellularis meningitidis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Micrococcus intracellularis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Micrococcus meningitidis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Micrococcus meningitidis cerebrospinalis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Neisseria weichselbaumii</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Neisseria meningitidis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_50294 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_50294">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_180255"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:50294</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>PsHV-1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Pacheco&apos;s disease virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Psittacid herpesvirus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Psittacid alphaherpesvirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_504568 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_504568">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:504568</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>trouts, salmons &amp; chars</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Salmoninae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_517 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_517">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_80840"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:517</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11491321</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bordetella</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_518 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_518">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_517"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:518</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:514</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8240949</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8782670</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9226899</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Alcaligenes bronchicanis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Alcaligenes bronchisepticus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus bronchicanis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus bronchisepticus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium bronchisepticus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Brucella bronchiseptica</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haemophilus bronchisepticus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bordetella bronchiseptica</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_520 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_520">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_517"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:520</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8240949</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacterium tussis-convulsivae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haemophilus pertussis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Hemophilus pertussis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Microbe de la coqueluche</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bordetella pertussis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_521 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_521">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_517"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:521</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:4074238</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bordetella avium</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_543 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_543">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91347"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:543</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10555323</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10555334</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16166704</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27620848</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Enterobacteraceae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>enterobacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gamma-3 proteobacteria</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Enterobacteriaceae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_54315 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_54315">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11095"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:54315</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:136447</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:64986</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:96055</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>BVDV type II</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>BVDV-2</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7747470</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Bovine viral diarrhea virus genotype 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine viral diarrhea virus type 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bovine viral diarrhea virus-2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bovine viral diarrhea virus type II</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>pestivirus type 4</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bovine viral diarrhea virus 2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_544448 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_544448">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1783272"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:544448</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_phylum"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Tenericutes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>&quot;Mollicutaeota&quot; Oren et al. 2015</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>&quot;Tenericutes&quot; Murray 1984</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mollicutota</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycoplasmatota</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_546272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_546272">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:546272</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19346311</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella melitensis str. ATCC 23457</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Brucella melitensis strain ATCC 23457</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Brucella melitensis ATCC 23457</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_548681 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_548681">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:548681</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Herpesvirales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5500 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5500">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5500</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Coccidioides</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_55601 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_55601">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_662"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:55601</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:28167</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:665</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21296930</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Achromobacter ichthyodermis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Listonella anguillara</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Listonella anguillarum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pseudomonas ichthyodermis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio ichthyodermis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio piscium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio piscium var. japonicus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Vibrio anguillarum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_55987 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_55987">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:55987</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:155284</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:86501</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Salmon isavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Isavirus salaris</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_560210 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_560210">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119088"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:560210</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Dintheria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_562 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_562">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_543"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:562</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1637691</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1806490</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:469598</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:662101</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:662104</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319482</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>E. coli</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Escherichia/Shigella coli</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus coli</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium coli</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium coli commune</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Enterococcus coli</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Escherichia coli</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5654 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5654">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2611352"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5654</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Trypanosomatidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5658 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5658">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5654"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5658</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Leishmania</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Leishmania &lt;genus&gt;</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5659 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5659">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38568"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5659</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:31284</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Leishmania (Leishmania) amazonensis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Leishmania mexicana amazonensis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Leishmania amazonensis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5661 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5661">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5661</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Leishmania (Leishmania) donovani</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Leishmania donovani</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5664 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5664">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38568"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5664</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Leishmania (Leishmania) major</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Leishmania tropica major</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Leishmania major</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_56690 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_56690">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2611341"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:56690</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:33701</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:5724</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12046599</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15734659</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22000167</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Tritrichomonas suis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5671 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5671">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5671</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:5662</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Leishmania (Leishmania) infantum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Leishmania donovani infantum</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Leishmania infantum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_568815 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_568815">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_444163"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:568815</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_strain"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:399127</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19653890</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Brucella microti str. CCM 4915</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Brucella microti strain CCM 4915</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Brucella sp. CCM 4915</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Brucella microti CCM 4915</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5690 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5690">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5654"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5690</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Trypanosoma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5691 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5691">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5690"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5691</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Trypanosoma (Trypanozoon) brucei</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Trypanosoma brucei subgroup</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Trypanosoma brucei</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5693 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5693">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5690"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5693</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Trypanosoma cruzi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5741 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5741">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2611341"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5741</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11432808</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19135417</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Giardia duodenalis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Giardia lamblia</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Lamblia intestinalis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Giardia intestinalis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5759 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5759">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5759</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Entamoeba histolytica</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5761 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5761">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2611352"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5761</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Naegleria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5762 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5762">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5761"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5762</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Naegleria gruberi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5763 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5763">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5761"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5763</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>brain-eating amoeba</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Naegleria fowleri</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5794 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5794">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5794</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_phylum"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>apicomplexans</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>apicomplexans</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Apicomplexa</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5800 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5800">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_423054"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5800</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Eimeria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5802 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5802">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5802</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Eimeria tenella</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5804 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5804">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5804</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Eimeria maxima</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5807 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5807">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_423054"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5807</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200815</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200816</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200817</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200818</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200819</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200820</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200821</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200822</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200823</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200824</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200825</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:2200826</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Cryptosporidium parvum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5809 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5809">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_423054"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5809</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Sarcocystids</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Sarcocystidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5811 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5811">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5809"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5811</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Toxoplasma gondii</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5820 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_422676"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5820</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Plasmodium</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5821 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5821">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_418101"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5821</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Plasmodium berghei</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5825 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5825">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_418101"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5825</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Plasmodium chabaudi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5833 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5833">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5833</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>malaria parasite P. falciparum</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Plasmodium (Laverania) falciparum</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Plasmodium falciparum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5850 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5850">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_418103"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5850</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Plasmodium knowlesi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5855 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5855">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_418103"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5855</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>malaria parasite P. vivax</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Haemamoeba vivax</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haemamoeba vivax Grassi and Feletti, 1890</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Plasmodium vivax</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5861 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5861">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_418101"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5861</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Plasmodium yoelli</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Plasmodium yoelii</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5863 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5863">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_422676"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5863</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Piroplasmids</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Piroplasmida</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5864 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5864">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5863"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5864</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Babesia</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5865 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5865">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5864"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5865</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Babesia bovis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5866 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5866">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5864"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5866</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Babesia bigemina</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5867 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5867">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5864"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5867</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Babesia canis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5873 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5873">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5863"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5873</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Theileria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5874 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5874">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5873"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5874</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Theileria annulata</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_5875 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5875">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5873"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:5875</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Theileria parva</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_590 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_590">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_543"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:590</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319519</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10939679</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12072558</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15653929</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15653930</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:3231714</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:37486130</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9731304</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Salmonella</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_59201 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_59201">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:59201</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subspecies"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:149049</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15653929</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15653930</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7149525</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Salmonella cholerae-suis subsp. cholerae-suis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella choleraesuis subsp. choleraesuis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica I</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica subsp. I</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica subsp. Subsp. I</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica subsp. Subsp. Ixxx</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Salmonella enterica subsp. enterica</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_594 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_594">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_59201"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:594</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:41510</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica serovar Gallinarum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella gallinarum</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Salmonella enterica subsp. enterica serovar Gallinarum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_6181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_6181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33317"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:6181</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Schistosoma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_6182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_6182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:6182</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Schistosoma japonicum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_6183 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_6183">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:6183</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Schistosoma mansoni</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_619591 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_619591">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10244"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:619591</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Monkeypox virus Zaire-96-I-16</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_620 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_620">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_543"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:620</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:26834722</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Shigella</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_622 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_622">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:622</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12054222</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Escherichia/Shigella dysenteriae</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus dysenteriae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus dysentericus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus shigae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Eberthella dysenteriae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Shigella shigae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Shigella dysenteriae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_623 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_623">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:623</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Escherichia flexneri</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Escherichia/Shigella flexneri</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Shigella paradysenteriae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Shigella flexneri</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_624 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_624">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:624</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacterium sonnei</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Shigella sonnei</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_629 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_629">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1903411"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:629</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Yersinia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Yersinia &lt;enterobacteria&gt;</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_632 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_632">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1649845"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:632</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15084509</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus pestis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium pestis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pasteurella pestis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pestisella pestis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Yersinia pseudotuberculosis subsp. pestis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Yersinia pestis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_633 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_633">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1649845"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:633</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1161941</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2223608</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23919959</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus pseudotuberkulosis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium pseudotuberculosis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pasteurella lymphangitidis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pasteurella pseudotuberculosis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Shigella pseudotuberculosis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Yersinia pseudotuberculosis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_6334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_6334">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119088"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:6334</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Trichina spiralis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Trichinella spiralis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_635 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_635">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91347"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:635</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Edwardsiella</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Asakusa group</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bartholomew group</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Edwardsiella &lt;enterobacteria&gt;</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_636 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_636">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_635"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:636</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1471792</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1471793</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27539016</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Edwardsiella anguillimortifera</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Paracolobactrum anguillimortiferum</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Edwardsiella tarda</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_641 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_641">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1236"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:641</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15143042</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:4954820</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8427811</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>gamma-3 proteobacteria</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Vibrionaceae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_642 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_642">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1236"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:642</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11155981</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12067377</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12807216</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1380286</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1380289</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15388703</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16560691</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17012583</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17158971</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19567585</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7520733</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8347521</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8934910</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Aeromonas</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_644 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_644">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_642"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:644</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1426505</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1426713</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1471787</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1471788</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:1538469</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:329135</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:329140</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:346633</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:346634</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582196</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582198</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582214</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582215</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582216</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582217</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582218</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582219</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582220</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582221</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582222</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582223</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582224</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582225</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582226</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582228</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582229</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582231</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582236</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582237</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582240</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582250</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582251</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582253</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582254</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582265</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582266</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582267</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582279</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582282</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582284</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582286</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582287</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582289</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582290</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582291</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582292</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582295</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582297</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582299</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582300</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582302</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582303</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582304</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582305</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582306</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582307</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582308</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582309</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582310</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582311</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582312</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582313</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582314</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582315</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582316</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582317</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582318</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582319</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582320</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582321</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582322</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582323</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:582324</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:98358</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16560691</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19965992</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:932684</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Aeromonas dourgesi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Aeromonas hydrophila (Chester 1901) Stanier 1943 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Aeromonas liquefaciens</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus hydrophilus fuscus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium hydrophilum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Proteus hydrophilus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Proteus ichthyosmius</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pseudomonas hydrophila</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Aeromonas hydrophila</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_645 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_645">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_642"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:645</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1055664</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:697046</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19965992</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus salmonicida</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium salmonicida</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Proteus salmonicida</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Aeromonas salmonicida</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_64895 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_64895">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:64895</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1618316</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10515907</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10758897</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16585709</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24744012</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27930271</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:28141502</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:30154058</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:30586413</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31454394</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31722850</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31836459</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:32320380</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:35816828</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:36748499</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7981102</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8573491</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8934900</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8995795</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9336916</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Lyme Disease Borrelia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Borrelia burgdorferi group</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Borrelia burgdorferi sensu lato</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Borreliella</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_662 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_662">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_641"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:662</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:705</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1371064</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17978204</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21057054</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21296930</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24409173</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:4935323</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7520733</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8590667</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Beneckea</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Listonella</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Microspira</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pacinia</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Vibrio</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_666 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_666">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_662"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:666</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:140100</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:376726</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1015934</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9272984</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillo virgola del Koch</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus cholerae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacillus cholerae-asiaticae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Kommabacillus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Liquidivibrio cholerae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Microspira comma</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pacinia cholerae-asiaticae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spirillum cholerae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Spirillum cholerae-asiaticae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio albensis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio cholera</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio cholerae biovar albensis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio cholerae bv. albensis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio cholerae-asiaticae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Vibrio comma</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Vibrio cholerae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_67780 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_67780">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_635"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:67780</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Edwardsiella ictaluri</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_691956 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_691956">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12058"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:691956</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:352473</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>DHV-1</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Duck hepatitis A virus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Duck hepatitis virus 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Duck hepatitis virus type 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Avihepatovirus A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_693995 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_693995">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:693995</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Coronavirinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_693997 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_693997">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2501931"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:693997</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Alphacoronavirus-1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Alphacoronavirus 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_694002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_694002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2501931"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:694002</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:156439</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Coronavirus group 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Group 2 species</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Coronavirus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Betacoronavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_694009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_694009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_694002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:694009</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:227859</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:311178</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>HCoV-SARS</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>SARS</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>SARSr-CoV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>SARSrCoV</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Human coronavirus (strain SARS)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>SARS-like coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>SARS-related coronavirus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Severe acute respiratory syndrome-related coronavirus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_70796 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_70796">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2946633"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:70796</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Tremovirus A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_70999 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_70999">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33340"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:70999</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>kissing bugs</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Triatominae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_712 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_712">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1236"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:712</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10843050</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15280320</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15388716</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17220461</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2223605</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:29923825</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Pasteurellaceae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_715 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_715">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_712"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:715</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1847295</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Haemophilus pleuropneumoniae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Actinobacillus pleuropneumoniae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_7164 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7164">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33340"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:7164</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Anopheles</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Anopheles &lt;genus&gt;</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_72273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_72273">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1236"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:72273</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Thiomicrospira group</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Thiothrix/Francisella group</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Thiotrichales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_724 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_724">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_712"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:724</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1736960</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Haemophilus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_727 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_727">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_724"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:727</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacterium influenzae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Coccobacillus pfeifferi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haemophilus meningitidis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Influenza-bacillus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacterium influenzae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Haemophilus influenzae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_731 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_731">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_712"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:731</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:163489</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:214923</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13130032</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:4333932</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Haemophilus agni</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haemophilus ovis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haemophilus somnifer</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haemophilus somnus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Hemophilus agni</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Histophilus ovis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Histophilus somni</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_738 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_738">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_712"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:738</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:5821848</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Haemophilus parasuis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Glaesserella parasuis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_747 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_747">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_712"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:747</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15184562</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacterium multocidum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Micrococcus gallicidus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pasteurella cholerae-gallinarum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Pasteurella gallicida</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Pasteurella multocida</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_75985 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_75985">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_712"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:75985</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:746</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10028248</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8782683</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Pasteurella haemolytica Newsom and Cross 1932 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mannheimia haemolytica</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_766 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_766">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28211"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:766</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11760958</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8240958</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>rickettsias</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>alpha-1 proteobacteria</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Rickettsiales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_76803 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_76803">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_76804"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:76803</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Arteriviridae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_76804 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_76804">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732506"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:76804</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Nidovirales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_77054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_77054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5873"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:77054</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:61430</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Theileria hirci</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Theileria lestoquardi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_7742 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7742">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33213"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:7742</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_clade"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Vertebrata</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>vertebrates</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>vertebrates</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Vertebrata &lt;vertebrates&gt;</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_777 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_777">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1236"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:777</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9226923</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Rickettsia burneti</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Rickettsia diaporica</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Coxiella burnetii</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_780 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_780">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_766"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:780</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10939649</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11491333</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:14662925</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9103608</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Rickettsia</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_7898 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7898">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117571"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:7898</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_superclass"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>fish</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>fishes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>ray-finned fishes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Actinopterygi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Osteichthyes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>bony fishes</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Actinopterygii</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_79668 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_79668">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1502"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:79668</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Clostridium perfringens C</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_7995 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7995">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186625"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:7995</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>catfishes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Siluriformes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_8015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_8015">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1489388"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:8015</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15062801</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>salmonids</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Salmonidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_8022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_8022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_504568"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:8022</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1311475</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>rainbow trout</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Oncorhynchus nerka mykiss</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Parasalmo mykiss</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmo mykiss</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Oncorhynchus mykiss</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_80840 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_80840">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28216"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:80840</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16403855</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Burkholderia/Oxalobacter/Ralstonia group</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Burkholderiales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_810 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_810">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3379134"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:810</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:83553</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319462</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11211265</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21048221</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21048222</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23620152</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25618261</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9103632</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9103637</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>&quot;Prowazekia&quot; Coles 1953</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bedsonia</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Chlamydophila</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Miyagawanella</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Rakeia</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Rickettsiaformis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Chlamydia</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_813 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_813">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_810"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:813</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10192388</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319462</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8102247</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8347519</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Chlamydozoon trachomatis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Rickettsia trachomae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Rickettsia trachomatis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Chlamydia trachomatis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_83334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_83334">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:83334</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_serotype"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Escherichia coli O157:H7</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_83554 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_83554">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_810"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:83554</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:812</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319462</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12807198</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8102247</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8347519</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Chlamydophila psittaci</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Chlamydozoon psittaci</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Ehrlichia psittaci</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Rickettsia psittaci</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Rickettsiaformis psittacosis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Chlamydia psittaci</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_83555 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_83555">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_810"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:83555</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319462</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12807198</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25618261</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Chlamydia psittaci (Lillie 1930) Page 1968</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Chlamydia psittaci serotype 1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Chlamydophila abortus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Chlamydia abortus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_83558 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_83558">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_810"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:83558</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:811</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319462</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8102247</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8347519</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Chlamydophila pneumoniae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Chlamydia pneumoniae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_83560 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_83560">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_810"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:83560</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319462</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>agent of mouse pneumonitis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Chlamydia trachomatis MoPn</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Chlamydia muridarum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_836 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_836">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_976"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:836</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15774632</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24158948</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25481042</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8186083</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8590687</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Porphyromonas</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_85007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_85007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1783272"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:85007</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:1761</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11837321</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1736962</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:19244447</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31157615</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Corynebacteriales</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Corynebacteriales Goodfellow and Jones 2015</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Corynebacteriineae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Corynebacteriineae corrig. Stackebrandt et al. 1997</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Corynebacterineae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacteriales Janke 1924 (Approved Lists 1980)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mycobacteriineae</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mycobacteriales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_85708 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_85708">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732092"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:85708</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasBroadSynonym>PCV2</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Porcine circovirus Type II</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Porcine circovirus type 2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Porcine circovirus-2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Porcine circovirus 2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_8782 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_8782">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_32561"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:8782</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>birds</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>avian</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>birds</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Aves</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_8825 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_8825">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:8825</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_infraclass"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Neognathae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_8835 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_8835">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1549675"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:8835</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>ducks</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Anas</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1549675"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9005</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:9099</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>turkeys</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Phasianidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_90062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_90062">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_173"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:90062</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Leptospira interrogans serovar Icterohaemorrhagiae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9031">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9031</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Gallus domesticus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>bantam</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chicken</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>chickens</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Gallus gallus domesticus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Phasianus gallus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Gallus gallus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_90370 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_90370">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_59201"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:90370</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:41530</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:601</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:72667</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10319519</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10758910</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15653930</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16558776</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9336938</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus typhi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacterium (subgen. Eberthella) typhi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella choleraesuis serovar Typhi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella choleraesuis typhi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica ser. typhi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica serotype Typhi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica serovar Typhi</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella typhi</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Salmonella enterica subsp. enterica serovar Typhi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_90371 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_90371">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_59201"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:90371</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:41532</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:59210</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:602</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10758910</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15653930</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9336938</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus typhimurium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella choleraesuis serotype typhimurium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica 1,4,[5],12,:i:1,2</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica ser. typhimurium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica serotype Typhimurium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica serovar Typhimurium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:1,2</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella typhi-murium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Salmonella typhimurium</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Salmonella enterica subsp. enterica serovar Typhimurium</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9103">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9103</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>common turkey</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>turkey</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>wild turkey</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Meleagris gallopavo</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_91061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_91061">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1239"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:91061</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_class"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bacillus/Lactobacillus/Streptococcus group</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Firmibacteria</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bacilli</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_91347 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_91347">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1236"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:91347</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:27620848</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Enterobacteriaceae and related endosymbionts</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Enterobacteriaceae group</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Enterobacteriales</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gamma-3 proteobacteria</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Enterobacterales</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_91561 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_91561">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314145"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:91561</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>even-toed ungulates &amp; whales</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Cetartiodactyla</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>even-toed ungulates &amp; whales</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Artiodactyla</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9224">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3073809"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9224</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>parrot</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>parrots</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Psittacidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_94063 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_94063">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:94063</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Leptospira sp. Pomona</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9443 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9443">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314146"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9443</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>primate</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Primata</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>primates</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Primates</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9479 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9479">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314293"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9479</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_parvorder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>New World monkeys</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>monkey</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>monkeys</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Platyrrhini</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_950 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_950">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_766"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:950</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11760958</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1736961</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7537065</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Potomac horse fever agent</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>equine monocytic ehrlichiosis agent</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Ehrlichia risticii</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Neorickettsia risticii</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9526 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9526">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314293"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9526</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_parvorder"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Catarrhini</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9534 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9534">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9526"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9534</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>African green monkey</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>African green monkeys</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>grivet</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>savanah monkey</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Cercopithecus aethiops</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Ceropithecus aethiops</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Simia aethiops</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Chlorocebus aethiops</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9526"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9606</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>human</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Homo sapiens</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9608 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9608">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_379584"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9608</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>dog, coyote, wolf, fox</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9611 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9611">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9608"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9611</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9612 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9612">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9611"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9612</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>gray wolf</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>grey wolf</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Canis lupus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9615 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9615">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9615</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subspecies"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>dog</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>dogs</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Canis borealis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Canis canis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Canis domesticus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Canis familiaris</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Canis lupus borealis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Canis lupus familiaris</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9625 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9625">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9608"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9625</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:68731</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:9609</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Fennecus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Vulpes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9654 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9654">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3072906"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9654</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>northern raccoon</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>raccoon</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Ursus lotor</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Procyon lotor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9669 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9669">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_169418"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9669</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subspecies"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:77150</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>black ferret</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>domestic ferret</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>ferret</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Mustela furo</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Mustela putorius furo</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9682 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9682">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33554"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9682</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Felis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9685 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9685">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9682"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9685</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:36475</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:17600185</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8581300</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8603894</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>cat</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>cats</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>domestic cat</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Felis domesticus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Felis silvestris catus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Felis catus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_976 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_976">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3379134"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:976</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_phylum"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:171554</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11541229</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11542017</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:28066339</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>BCF group</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bacteroides-Cytophaga-Flexibacter group</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>CFB group</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Cytophaga-Flexibacter-Bacteroides phylum</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>&quot;Bacteroidota&quot; Whitman et al. 2018</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bacteroidetes</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>CFB group bacteria</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Sphingobacteria</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bacteroidota</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9768 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9768">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91561"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9768</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>sei whale</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Balaenoptera borealis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9788 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9788">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314145"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9788</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>horses</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Equidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9796 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9796">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9788"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9796</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>domestic horse</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>equine</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>horse</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Equus przewalskii f. caballus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Equus przewalskii forma caballus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Equus caballus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9823 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9823">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91561"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9823</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>pig</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>pigs</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>swine</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>wild boar</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Sus scrofa</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9850 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9850">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_35500"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9850</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>deer</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Cervidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9895 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9895">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_35500"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9895</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_family"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bovidae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9900 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9900">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_27592"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9900</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Bison</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9901 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9901">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9900"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9901</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>American bison</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Bison</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bos (Bison) bison</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bos bison</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bison bison</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9913 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9913">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_27592"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9913</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:272461</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>bovine</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>cow</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>dairy cow</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>domestic cattle</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>domestic cow</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>ox</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Bos bovis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bos primigenius taurus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Bos taurus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9925 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9925">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9963"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9925</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:57076</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>domestic goat</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>goat</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>goats</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Capra aegagrus hircus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Capra hircus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9935 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9935">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9963"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9935</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_genus"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Ovis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9940 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9940">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9935"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9940</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:9936</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>domestic sheep</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>lambs</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>sheep</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>wild sheep</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Ovis ammon aries</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Ovis orientalis aries</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Ovis ovis</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Ovis aries</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_996 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_996">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_200644"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:996</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:29531</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:11</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11594628</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16560903</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:29593693</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Chondrococcus columnaris</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Cytophaga columnaris</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Flavobacterium columnare (Bernardet and Grimont 1989) Bernardet et al. 1996</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Flexibacter columnaris</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Flexibacter columnaris (ex Davis 1922) Bernardet and Grimont 1989</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Flavobacterium columnare</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9963 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9963">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9895"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9963</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_subfamily"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <rdfs:label>Caprinae</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9986 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9986">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314147"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9986</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_species"/>
        <oboInOwl:hasAlternativeId>NCBITaxon:34833</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>NCBITaxon:9985</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>European rabbit</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Japanese white rabbit</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>domestic rabbit</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>rabbit</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>rabbits</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Lepus cuniculus</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Oryctolagus cuniculus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9989 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9989">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_314147"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCBITaxon:9989</metadata:prefixIRI>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncbitaxon.owl"/>
        <ncbitaxon:has_rank rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_order"/>
        <oboInOwl:hasDbXref>GC_ID:1</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>rodent</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>ncbi_taxonomy</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>rodents</oboInOwl:hasRelatedSynonym>
        <rdfs:label>Rodentia</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C85994 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C85994">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCIT:C85994</metadata:prefixIRI>
        <obo:IAO_0000115>A test to determine if a subject has ever had a tuberculosis infection. A small amount of purified tuberculosis protein is placed under the skin of the forearm and a positive skin reaction indicates previous exposure to Mycobacterium tuberculosis.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncit.owl"/>
        <rdfs:label>Tuberculin Skin Test</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OAE_0000001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OAE_0000001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000061"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OAE:0000001</metadata:prefixIRI>
        <obo:IAO_0000115>a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event.</obo:IAO_0000115>
        <obo:IAO_0000116>Melanie Courtot and YH: More work is needed on how to restrict the scope of a term to be an &apos;adverse event&apos;, notably regarding temporal association. When is an appropirate time interval between a medical intervention and an adverse event observed? One week, one month, one year, or a lifetime? For some well-studied medical interventions (e.g., administration of many vaccines or drugs), we probably have a general idea. For many new interventions, we don&apos;t know much. In OAE, this issue is associated with defining the &apos;adverse event incubation time&apos;.</obo:IAO_0000116>
        <obo:IAO_0000116>YH: An adverse event is a process that has specified output of some adverse medical outcome (e.g., symptom, sign or accident) after a medical intervention (or process) (e.g., administration of drug or vaccine). The medical intervention can be an administration of a drug, a vaccine (i.e., vaccination), or a special nutritional product (for example, dietary supplement, infant formula, medical food), surgery, or usage of a medical device.</obo:IAO_0000116>
        <obo:IAO_0000116>YH: An adverse event is possibly induced by the medical intervention. It can be caused by the medical intervention, or may not be caused by the medical intervention. One ultimate goal (or the goal in clinics) of study adverse events is to assess if the adverse event outcome is due to the medical intervention.</obo:IAO_0000116>
        <obo:IAO_0000116>YH: In development of OAE, we initially use vaccine adverse event as our use case. A vaccine adverse event is associated with a vaccination (i.e. a medical intervention), regardless of whether it is considered vaccine-related, and includes any side effect, injury, toxicity, or sensitivity reaction or significant failure of immunization (i.e., a pharmacologic action).
Ref: Baylor NW and Midthum K. Regulation and testing of vaccines. In: Vaccines (Editors: Plotkin S, Orenstein W, and Offit P). 2008.  p1623.</obo:IAO_0000116>
        <obo:IAO_0000116>YH: The current term &apos;adverse event&apos; is different from the term definition shown in our paper: He Y, Xiang Z, Sarntivijai S, Toldo L, Ceusters W. OAE: a realism-based biomedical ontology for the representation of adverse events. Adverse Event Representation Workshop, International Conference on Biomedical Ontologies (ICBO), University at Buffalo, NY, July 26-30, 2011. Full lenghth conference proceeding paper.  

We  made the name changing in order to make OAE cover the broader sense of the &apos;adverse event&apos; which does not assume definite causal effect between an adverse event and a medical intervention. In current definition, the adverse event emphasizes the time association and assumes a likelihood of such a causal association. This term &apos;adverse event&apos; is stil under the OGMS:pathological bodily process.

The &apos;adverse event&apos; defined in the above paper has now been changed to a new term: &apos;causal adverse event&apos;. See more information in the new publication: Yongqun He Y, Sirarat Sarntivijai, Yu Lin, Zuoshuang Xiang, Abra Guo, Shelley Zhang, Desikan Jagannathan, Luca Toldo, Cui Tao and Barry Smith. OAE: The Ontology of Adverse Events. Journal of Biomedical Semantics. 2014, 5:29  doi:10.1186/2041-1480-5-29. PMID: 25093068.PMCID: PMC4120740.</obo:IAO_0000116>
        <obo:IAO_0000116>YH: The main scope of OAE includes: (1) represent terms and relations in the area of adverse events, (2) assess possible associations between an adverse event and a medical intervention, particularly, identify any causal effect of a medical intervention to an adverse event; and (2) understand the mechanism (including molecular mechanisms) of causal adverse events.</obo:IAO_0000116>
        <obo:IAO_0000116>YH: There has been discussion regarding whether the term &apos;side effect&apos; is an alternative term for &apos;adverse event&apos;. In AERO, the term &apos;AERO:adverse event&apos; represents a subset of those adverse events for which causality has been established. In OAE, an adverse event for which causality has been established is called &apos;causal adverse event&apos;.</obo:IAO_0000116>
        <obo:IAO_0000117>Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000118>AE</obo:IAO_0000118>
        <obo:IAO_0000118>adverse reaction</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Adverse_event</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/pubmed/25093068</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oae.owl"/>
        <rdfs:comment>The OAE official website is: http://www.oae-ontology.org/.</rdfs:comment>
        <rdfs:label>adverse event</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OAE_0000004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OAE_0000004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OAE_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OAE:0000004</metadata:prefixIRI>
        <obo:IAO_0000115>an adverse event that occurs after a vaccination.</obo:IAO_0000115>
        <obo:IAO_0000117>YH</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oae.owl"/>
        <rdfs:label>vaccine adverse event</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OAE_0000055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OAE_0000055">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OAE:0000055</metadata:prefixIRI>
        <obo:IAO_0000115>A contraindication is a disposition that increases the risk of harm involved in using a particular drug, carrying out a medical procedure, or engaging in a particular activity such that the risk of harm exceeds a threshold. An contraindication serves as a reason to withhold a certain medical treatment.</obo:IAO_0000115>
        <obo:IAO_0000117>Yongqun He, Sirarat Sarntivijai,  Mathias Brochhausen,  William Hogan, ‎Philip E. Empey</obo:IAO_0000117>
        <obo:IAO_0000119>http://en.wikipedia.org/wiki/Contraindication</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oae.owl"/>
        <rdfs:label>contraindication</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OAE_0000097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OAE_0000097">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OAE_0000004"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OAE:0000097</metadata:prefixIRI>
        <obo:IAO_0000115>an adverse event that is induced by a vaccination.</obo:IAO_0000115>
        <obo:IAO_0000117>YH</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/oae.owl"/>
        <rdfs:label>vaccine-induced adverse event</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000011">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000011</metadata:prefixIRI>
        <obo:IAO_0000111>planned process</obo:IAO_0000111>
        <obo:IAO_0000112>Injecting mice with a vaccine in order to test its efficacy</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A process that realizes a plan which is the concretization of a plan specification.</obo:IAO_0000115>
        <obo:IAO_0000116>&apos;Plan&apos; includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn&apos;t have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.)</obo:IAO_0000116>
        <obo:IAO_0000116>We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some 
objectives is a planned process.</obo:IAO_0000116>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000119>branch derived</obo:IAO_0000119>
        <obo:IAO_0000232>6/11/9: Edited at workshop. Used to include: is initiated by an agent</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call)</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">planned process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000017"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000014</metadata:prefixIRI>
        <obo:IAO_0000111>regulator role</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Fact sheet - Regulating the companies The role of the regulator. Ofwat is the economic regulator of the water and sewerage industry in England and Wales.  http://www.ofwat.gov.uk/aptrix/ofwat/publish.nsf/Content/roleofregulator_factsheet170805</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">a regulatory role involved with making and/or enforcing relevant legislation and governmental orders</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person:Jennifer Fostel</obo:IAO_0000117>
        <obo:IAO_0000118>regulator</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">regulator role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000017"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000016</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">regulation-assigned role</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Approval letter</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">Regulation-assigned role is a regulatory role defined by legislation or governmental orders</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person: Jennifer Fostel</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">regulation-assigned role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000017</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">regulatory role</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Regulatory agency, Ethics committee, Approval letter; example:  Browse these EPA Regulatory Role subtopics  http://www.epa.gov/ebtpages/enviregulatoryrole.html  Feb 29, 2008</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">GROUP:  Role branch</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI, CDISC</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">govt agents responsible for creating regulations; proxies for enforcing regulations.  CDISC definition:  regulatory authorities. Bodies having the power to regulate. NOTE: In the ICH GCP guideline the term includes the authorities that review submitted clinical data and those that conduct inspections. These bodies are sometimes referred to as competent</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">regulatory role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000047">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000047</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">processed material</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">Is a material entity that is created or changed during material processing.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">processed material</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000067 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000067">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000067</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">evaluant role</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">When a specimen of blood is assayed for glucose concentration, the blood has the evaluant role. When measuring the mass of a mouse, the evaluant is the mouse. When measuring the time of DNA replication, the evaluant is the DNA. When measuring the intensity of light on a surface, the evaluant is the light source.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Role call - 17nov-08: JF and MC think an evaluant role is always specified input of a process. Even in the case where we have an assay taking blood as evaluant and outputting blood, the blood is not the specified output at the end of the assay (the concentration of glucose in the blood is)</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">examples of features that could be described in an evaluant: quality.... e.g. &quot;contains 10 pg/ml IL2&quot;, or &quot;no glucose detected&quot;)</obo:IAO_0000116>
        <obo:IAO_0000117>GROUP:  Role Branch</obo:IAO_0000117>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000232>Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:RO_0000052 rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <rdfs:label xml:lang="en">evaluant role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000070 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000070">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000441"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000027"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
                                <owl:someValuesFrom>
                                    <owl:Class>
                                        <owl:intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
                                            <owl:Restriction>
                                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
                                            </owl:Restriction>
                                        </owl:intersectionOf>
                                    </owl:Class>
                                </owl:someValuesFrom>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000070</metadata:prefixIRI>
        <obo:BFO_0000055 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000067"/>
        <obo:IAO_0000111 xml:lang="en">assay</obo:IAO_0000111>
        <obo:IAO_0000112>Assay the wavelength of light emitted by excited Neon atoms. Count of geese flying over a house.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that has the objective to produce information about a material entity (the evaluant) by examining it.</obo:IAO_0000115>
        <obo:IAO_0000116>12/3/12: BP: the reference to the &apos;physical examination&apos; is included to point out that a prediction is not an assay, as that does not require physical examiniation.</obo:IAO_0000116>
        <obo:IAO_0000116>Discussion on OBI call 2023-05-01 resulted in an agreement to revise the textual definition of &apos;assay&apos;.  https://github.com/obi-ontology/obi/issues/1683.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">measuring</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">scientific observation</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0001847>study assay</obo:OBI_0001847>
        <obo:OBI_9991118>any method</obo:OBI_9991118>
        <rdfs:label xml:lang="en">assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000086 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000086">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000086</metadata:prefixIRI>
        <obo:IAO_0000111>reagent role</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Buffer, dye, a catalyst, a solvating agent.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON:Matthew Brush</obo:IAO_0000117>
        <obo:IAO_0000118>reagent</obo:IAO_0000118>
        <obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
        <obo:IAO_0000232>Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term.

May 28 2013. Updated definition taken from ReO based on discussions initiated in Philly 2011 workshop.  Former defnition described a narrower view of reagents in chemistry that restricts bearers of the role to be chemical entities (&quot;a role played by a molecular entity used to produce a chemical reaction to detect, measure, or produce other substances&quot;).  Updated definition allows for broader view of reagents in the domain of biomedical research to include larger materials that have parts that participate chemically in a molecular reaction or interaction.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:comment>(copied from ReO)
Reagents are distinguished from instruments or devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique.  By contrast, instruments do not participate in a chemical reaction/interaction during the technique.

Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not.  It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance will realize only one of these roles in the execution of a given assay or technique. For example, taq polymerase can bear a reagent role or an evaluant role.  In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.

In regard to the statement that reagents are &apos;distinct&apos; from the specified outputs of a technique, note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role.  For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a &apos;nucleic acid molecule&apos;) that is distinct from the identity of the dNTPs that comprise it.  Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of &apos;reagent-ness&apos; is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).</rdfs:comment>
        <rdfs:label xml:lang="en">reagent role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000094 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000094">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000094</metadata:prefixIRI>
        <obo:IAO_0000111>material processing</obo:IAO_0000111>
        <obo:IAO_0000112>A cell lysis, production of a cloning vector, creating a buffer.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A planned process which results in physical changes in a specified input material</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Philippe Rocca Serra</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">material transformation</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">OBI branch derived</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
        <rdfs:label xml:lang="en">material processing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000181</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">population</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PMID12564891. Environ Sci Technol. 2003 Jan 15;37(2):223-8. Effects of historic PCB exposures on the reproductive success of the Hudson River striped bass population.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area</obo:IAO_0000115>
        <obo:IAO_0000116>1/28/2013, BP, on the call it was raised that we may want to switch to an external ontology for all populatin terms: 
http://code.google.com/p/popcomm-ontology/</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">adapted from Oxford English Dictionnary</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">rem1: collection somehow always involve a selection process</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">population</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000237 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000237">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0006955"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000237</metadata:prefixIRI>
        <obo:IAO_0000111>antigen role</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">A role of a material entity that is being recognized in whole or in part by receptors of the immune system such as antibodies or T cell receptors.</obo:IAO_0000115>
        <obo:IAO_0000116>An antigen is a substance that prompts the generation of antibodies and can cause an immune response.  Wikipedia  http://en.wikipedia.org/wiki/Antigen. In the strict sense, immunogens are those substances that elicit a response from the immune system, whereas antigens are defined as substances that bind to specific antibodies. Not all antigens produce an immunogenic response, but all immunogens are antigens</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Role Branch</obo:IAO_0000117>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000232>9Mar09 waiting for discussion with immunology terms</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">antigen role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000245">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000245</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">organization</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">BP: The definition summarizes long email discussions on the OBI developer, roles, biomaterial and denrie branches. It leaves open if an organization is a material entity or a dependent continuant, as no consensus was reached on that.  The current placement as material is therefore temporary, in order to move forward with development. Here is the entire email summary, on which the definition is based:

1) there are organization_member_roles (president, treasurer, branch
editor), with individual persons as bearers

2) there are organization_roles (employer, owner, vendor, patent holder)

3) an organization has a charter / rules / bylaws, which specify what roles
there are, how they should be realized, and how to modify the
charter/rules/bylaws themselves.

It is debatable what the organization itself is (some kind of dependent
continuant or an aggregate of people). This also determines who/what the
bearer of organization_roles&apos; are. My personal favorite is still to define
organization as a kind of &apos;legal entity&apos;, but thinking it through leads to
all kinds of questions that are clearly outside the scope of OBI.

Interestingly enough, it does not seem to matter much where we place
organization itself, as long as we can subclass it (University, Corporation,
Government Agency, Hospital), instantiate it (Affymetrix, NCBI, NIH, ISO,
W3C, University of Oklahoma), and have it play roles.

This leads to my proposal: We define organization through the statements 1 -
3 above, but without an &apos;is a&apos; statement for now. We can leave it in its
current place in the is_a hierarchy (material entity) or move it up to
&apos;continuant&apos;. We leave further clarifications to BFO, and close this issue
for now.</obo:IAO_0000116>
        <obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Susanna Sansone</obo:IAO_0000117>
        <obo:IAO_0000119>GROUP: OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000272">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000272</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">protocol</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PCR protocol, has objective specification, amplify DNA fragment of interest, and has action specification describes the amounts of experimental reagents used (e..g. buffers, dNTPS, enzyme), and the temperature and cycle time settings for running the PCR.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PlanAndPlannedProcess Branch</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">OBI branch derived + wikipedia (http://en.wikipedia.org/wiki/Protocol_%28natural_sciences%29)</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0001847>study protocol</obo:OBI_0001847>
        <rdfs:label xml:lang="en">protocol</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000274 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000274">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000434"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000652"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000444"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                                <owl:someValuesFrom>
                                    <owl:Class>
                                        <owl:intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
                                            <owl:Restriction>
                                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000444"/>
                                            </owl:Restriction>
                                        </owl:intersectionOf>
                                    </owl:Class>
                                </owl:someValuesFrom>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000274</metadata:prefixIRI>
        <obo:BFO_0000055 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
        <obo:BFO_0000055 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000444"/>
        <obo:IAO_0000111>adding a material entity into a target</obo:IAO_0000111>
        <obo:IAO_0000112>Injecting a drug into a mouse. Adding IL-2 to a cell culture. Adding NaCl into water.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">is a process with the objective to place a material entity bearing the &apos;material to be added role&apos; into a material bearing the &apos;target of material addition role&apos;.</obo:IAO_0000115>
        <obo:IAO_0000116>Class was renamed from &apos;administering substance&apos;, as this is commonly used only for additions into organisms.</obo:IAO_0000116>
        <obo:IAO_0000117>BP</obo:IAO_0000117>
        <obo:IAO_0000119>branch derived</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">adding a material entity into a target</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000281">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000429"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000422"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000426"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000429"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000281</metadata:prefixIRI>
        <obo:IAO_0000111>intraperitoneal injection</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe</obo:IAO_0000115>
        <obo:IAO_0000117>BP</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>intraperitoneal injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000319</metadata:prefixIRI>
        <obo:IAO_0000111>material to be added role</obo:IAO_0000111>
        <obo:IAO_0000112>drug added to a buffer contained in a tube; substance injected into an animal;</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A role of a material entity that is realized in an &quot;adding a material entity into a target&quot; process where the bearer of the role is added into another material entity (the target).</obo:IAO_0000115>
        <obo:IAO_0000117>Role Branch</obo:IAO_0000117>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000232>9 March 09 from discussion with PA branch</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">material to be added role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000383 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000383">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000383</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">transfer function</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A transfer function is a function to displace a material from one location to another.</obo:IAO_0000115>
        <obo:IAO_0000117>Bill Bug</obo:IAO_0000117>
        <obo:IAO_0000117>Daniel Schober</obo:IAO_0000117>
        <obo:IAO_0000117>Frank Gibson</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">transfer function</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000422 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000422">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000968"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000422</metadata:prefixIRI>
        <obo:IAO_0000111>syringe</obo:IAO_0000111>
        <obo:IAO_0000112>Accuracy of oral liquid measuring devices: comparison of dosing cup and oral dosing syringe.Ann Pharmacother. 2008 Jan;42(1):46-52. Epub 2007 Dec 4. PMID: 18056832</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A processed material which is used to introduce or draw fluids from a material entity. A syringe is made of a piston and body. the movement of the piston in the body determines the amount/volume of fluid to inject or draw</obo:IAO_0000115>
        <obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000119>OBI Instrument adapted from Wikipedia</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000383"/>
        <rdfs:label>syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000426 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000426">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000422"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000274"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000434"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000426</metadata:prefixIRI>
        <obo:IAO_0000111>injection</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">Multiple Small-Dose Injections Can Reduce the Passage of Sclerosant Foam into Deep Veins During Foam Sclerotherapy for Varicose Veins. Eur J Vasc Endovasc Surg. 2008 Oct 13. PMID: 18922712</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">injection is process which aims at introducing a compound or a mixture into a material entity (either biological entity or instrument) by relying on devices such as syringe or injector connection, attached or forced into a vascular system (veins of an organism or tubes of a machine) or in a tissue.</obo:IAO_0000115>
        <obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000119>OBI Biomaterial</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0000417 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000434"/>
        <rdfs:label xml:lang="en">injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000429 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000429">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600007"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002358"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000429</metadata:prefixIRI>
        <obo:IAO_0000111>intraperitoneal administration</obo:IAO_0000111>
        <obo:IAO_0000112>Rats were injected intraperitoneally with either rrIL-6 (250 ng/0.5 ml) or equal-volume sterile saline twice within an interval of 24 h</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">The administration of a substance into the peritoneum of an organism</obo:IAO_0000115>
        <obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>intraperitoneal administration</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000434 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000434">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000686"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000434</metadata:prefixIRI>
        <obo:IAO_0000111>adding material objective</obo:IAO_0000111>
        <obo:IAO_0000112>creating a mouse infected with LCM virus</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity</obo:IAO_0000115>
        <obo:IAO_0000117>BP</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">adding material objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000441 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000441">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000441</metadata:prefixIRI>
        <obo:IAO_0000111>assay objective</obo:IAO_0000111>
        <obo:IAO_0000112>the objective to determine the weight of a mouse.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)</obo:IAO_0000115>
        <obo:IAO_0000117>PPPB branch</obo:IAO_0000117>
        <obo:IAO_0000119>PPPB branch</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">assay objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000444 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000444">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000274"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000444</metadata:prefixIRI>
        <obo:IAO_0000111>target of material addition role</obo:IAO_0000111>
        <obo:IAO_0000112>peritoneum of an animal receiving an interperitoneal injection; solution in a tube receiving additional material; location of absorbed material following a dermal application.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A role of a material entity that is realized in an &quot;adding a material entity into a target&quot; process where the bearer of the role (the target) receives the addition of another material entity.</obo:IAO_0000115>
        <obo:IAO_0000116>From Branch discussion with BP, AR, MC -- there is a need for the recipient to interact with the administered material.  for example, a tooth receiving a filling was not considered to be a target role.</obo:IAO_0000116>
        <obo:IAO_0000117>GROUP:  Role Branch</obo:IAO_0000117>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:RO_0000052 rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <rdfs:label xml:lang="en">target of material addition role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000450 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000450">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000014"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000450</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">regulatory agency</obo:IAO_0000111>
        <obo:IAO_0000112>The US Environmental Protection Agency</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government.</obo:IAO_0000115>
        <obo:IAO_0000117>GROUP: OBI Biomaterial Branch</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: en.wikipedia.org/wiki/Regulator</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">regulatory agency</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000456">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000456</metadata:prefixIRI>
        <obo:IAO_0000111>material transformation objective</obo:IAO_0000111>
        <obo:IAO_0000112>The objective to create a mouse infected with LCM virus. The objective to create a defined solution of PBS.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">an objective specifiction that creates an specific output object from input materials.</obo:IAO_0000115>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">artifact  creation objective</obo:IAO_0000118>
        <obo:IAO_0000119>GROUP: OBI PlanAndPlannedProcess Branch</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">material transformation objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000457 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000457">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000458"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000457</metadata:prefixIRI>
        <obo:IAO_0000111>manufacturing</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A planned process with the objective to produce a processed material which will have a function for future use.</obo:IAO_0000115>
        <obo:IAO_0000116>A person or organization (having manufacturer role) is a participant in this process</obo:IAO_0000116>
        <obo:IAO_0000116>Manufacturing implies reproducibility and responsibility AR</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">This includes a single scientist making a processed material for personal use.</obo:IAO_0000116>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000119>GROUP: OBI PlanAndPlannedProcess Branch</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0000293 rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
        <rdfs:label xml:lang="en">manufacturing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000458 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000458">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000458</metadata:prefixIRI>
        <obo:IAO_0000111>manufacturing objective</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">is the objective to manufacture a material of a certain function (device)</obo:IAO_0000115>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Frank Gibson</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000119>GROUP: OBI PlanAndPlannedProcess Branch</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">manufacturing objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000571 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000571">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000571</metadata:prefixIRI>
        <obo:IAO_0000111>manufacturer role</obo:IAO_0000111>
        <obo:IAO_0000112>With respect to The Accuri C6 Flow Cytometer System, the organization Accuri bears the role manufacturer role.  With respect to a transformed line of tissue culture cells derived by a specific lab, the lab whose personnel isolated the cll line bears the role manufacturer role.  With respect to a specific antibody produced by an individual scientist, the scientist who purifies, characterizes and distributes the anitbody bears the role manufacturer role.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process.</obo:IAO_0000115>
        <obo:IAO_0000117>GROUP:  Role Branch</obo:IAO_0000117>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>manufacturer role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000576 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000576">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000576</metadata:prefixIRI>
        <obo:IAO_0000111>scattered molecular aggregate</obo:IAO_0000111>
        <obo:IAO_0000112>the sodium and chloride ions in a glass of salt water</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">Collective</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. With inspiration from the paper Granularity, scale and collectivity: When size does and does not matter, Alan Recto, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0000643 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <rdfs:label xml:lang="en">scattered molecular aggregate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000652 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000652">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000686"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000652</metadata:prefixIRI>
        <obo:IAO_0000111>material combination</obo:IAO_0000111>
        <obo:IAO_0000112>Mixing two fluids. Adding salt into water. Injecting a mouse with PBS.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">is a material processing with the objective to combine two or more material entities as input into a single material entity as output.</obo:IAO_0000115>
        <obo:IAO_0000116>created at workshop as parent class for &apos;adding material into target&apos;, which is asymmetric, while combination encompasses all addition processes.</obo:IAO_0000116>
        <obo:IAO_0000117>bp</obo:IAO_0000117>
        <obo:IAO_0000119>bp</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0000293 rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <rdfs:label>material combination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000673 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000673">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000675"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000673</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">statistical hypothesis test</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test.</obo:IAO_0000115>
        <obo:IAO_0000117>James Malone</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">statistical hypothesis test</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000675 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000675">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000675</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">statistical hypothesis test objective</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
        <obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
        <obo:IAO_0000118>hypothesis test objective</obo:IAO_0000118>
        <obo:IAO_0000119>WEB:  http://en.wikipedia.org/wiki/Statistical_hypothesis_testing</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">statistical hypothesis test objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000685 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000685">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000652"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000686"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000685</metadata:prefixIRI>
        <obo:IAO_0000111>creating a mixture of molecules in solution</obo:IAO_0000111>
        <obo:IAO_0000112>The production of PBS</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">is a process with the objective to prepare a liquid solution of one or more chemicals at desired concentrations.</obo:IAO_0000115>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000119>PERSON: Helen Parkinson</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0000293 rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/OBI_0302729"/>
        <obo:OBI_0000417 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
        <obo:OBI_0000417 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000686"/>
        <rdfs:label>creating a mixture of molecules in solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000686 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000686">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000456"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000686</metadata:prefixIRI>
        <obo:IAO_0000111>material combination objective</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">is an objective to obtain an output material that contains several input materials.</obo:IAO_0000115>
        <obo:IAO_0000117>PPPB branch</obo:IAO_0000117>
        <obo:IAO_0000119>bp</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>material combination objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000712 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000712">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003456"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000725"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
                                <owl:someValuesFrom>
                                    <owl:Class>
                                        <owl:intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
                                            <owl:Restriction>
                                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000718"/>
                                            </owl:Restriction>
                                        </owl:intersectionOf>
                                    </owl:Class>
                                </owl:someValuesFrom>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
                                <owl:someValuesFrom>
                                    <owl:Class>
                                        <owl:intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
                                            <owl:Restriction>
                                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000725"/>
                                            </owl:Restriction>
                                        </owl:intersectionOf>
                                    </owl:Class>
                                </owl:someValuesFrom>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000712</metadata:prefixIRI>
        <obo:BFO_0000055 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000725"/>
        <obo:IAO_0000111>pathogen challenge</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">The administration of a live pathogenic organism to a host.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>pathogen challenge</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000718 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000718">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000063"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000718</metadata:prefixIRI>
        <obo:IAO_0000111>pathogen role</obo:IAO_0000111>
        <obo:IAO_0000112>Pathogen: An agent of disease. A disease producer. The term pathogen most commonly is used to refer to infectious organisms. These include bacteria (such as staph), viruses (such as HIV), and fungi (such as yeast). Less commonly, pathogen refers to a noninfectious agent of disease such as a chemical.   http://www.medterms.com/script/main/art.asp?articlekey=6383</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">pathogen role is a role which inheres in an organism and realized in the process of disease course in the organism bearing host role caused by the organism bearing pathogen role</obo:IAO_0000115>
        <obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000232>6 April 2009:  from the Vaccine Community</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:RO_0000052 rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <rdfs:label>pathogen role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000725 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000725">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000725</metadata:prefixIRI>
        <obo:IAO_0000111>host role</obo:IAO_0000111>
        <obo:IAO_0000112>In biology, a host is an organism that harbors a virus or parasite, or a mutual or commensal symbiont, typically providing nourishment and shelter.  http://en.wikipedia.org/wiki/Host_(biology)  30 March 09</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role</obo:IAO_0000115>
        <obo:IAO_0000116>30Mar09 virus reproducing inside a cell; bacteria causing a disease, host can be harmed or not.  we want to avoid a cat sitting on my lap and an animal care technician; these are not examples or hosts; dental cares = on tooth, but part of outer layer of tooth, so covered by &quot;within&quot; in the definition</obo:IAO_0000116>
        <obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
        <obo:IAO_0000119>30 Mar09 submitted by vaccine community</obo:IAO_0000119>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000119>http://en.wikipedia.org/wiki/Host_(biology)</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:RO_0000052 rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <rdfs:label>host role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000750 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000750">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000750</metadata:prefixIRI>
        <metadata:treeView rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
        <obo1:part_of rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
        <obo:IAO_0000111>independent variable specification</obo:IAO_0000111>
        <obo:IAO_0000112>In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, disease status is the independent variable.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2/2/2009 Original definition - In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled.</obo:IAO_0000116>
        <obo:IAO_0000116>In the Philly 2013 workshop the label was chosen to distinguish it from &quot;dependent variable&quot; as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling</obo:IAO_0000116>
        <obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000118>experimental factor</obo:IAO_0000118>
        <obo:IAO_0000118>independent variable</obo:IAO_0000118>
        <obo:IAO_0000119>Web: http://en.wikipedia.org/wiki/Dependent_and_independent_variables</obo:IAO_0000119>
        <obo:IAO_0000232>2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0001847>study factor</obo:OBI_0001847>
        <rdfs:label xml:lang="en">study design independent variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000751 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000751">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000751</metadata:prefixIRI>
        <metadata:treeView rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
        <obo1:part_of rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
        <obo:IAO_0000111>dependent variable specification</obo:IAO_0000111>
        <obo:IAO_0000112>In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, the gene expression is the dependent variable.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">2/2/2009 In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled.</obo:IAO_0000116>
        <obo:IAO_0000116>In the Philly 2013 workshop the label was chosen to distinguish it from &quot;dependent variable&quot; as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling</obo:IAO_0000116>
        <obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000118>dependent variable</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Dependent_and_independent_variables</obo:IAO_0000119>
        <obo:IAO_0000232>2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">study design dependent variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000806 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000806">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000806</metadata:prefixIRI>
        <obo:IAO_0000111>material maintenance objective</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">An objective specification maintains some or all of the qualities of a material over time.</obo:IAO_0000115>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000119>PERSON: Bjoern Peters</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>material maintenance objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000835 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000835">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
                        </owl:unionOf>
                    </owl:Class>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000571"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000835</metadata:prefixIRI>
        <obo:IAO_0000111>manufacturer</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">A person or organization that has a manufacturer role.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>manufacturer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000838 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000838">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000806"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000838</metadata:prefixIRI>
        <obo:IAO_0000111>material maintenance</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">A planned process with the objective to maintain some or all of the characteristics of an input material over time.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>material maintenance</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000852 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000852">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000852</metadata:prefixIRI>
        <obo:IAO_0000111>record of missing knowledge</obo:IAO_0000111>
        <obo:IAO_0000112>A statement in a journal article indicating that the age of a patient at the onset of disease is not known. A statement indicating that the weight of a mouse was not measured.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">An information content entity created to indicate that information about something is not available to the person recording it.</obo:IAO_0000115>
        <obo:IAO_0000116>This class should probably end up in IAO. It could be further breaken down to indicate different kinds of lack of knowledge, e.g. inability to determine something vs. no attempt made to determine something vs. no informatino available if it was even attempted to determine something. The design pattern should be generalizable. &apos;unknown sex&apos; is the first example, and needed immediately.</obo:IAO_0000116>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000119></obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>record of missing knowledge</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000938 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000938">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0001938"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000938</metadata:prefixIRI>
        <obo:IAO_0000111>categorical measurement datum</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A measurement datum that is reported on a categorical scale.</obo:IAO_0000115>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000118>nominal mesurement datum</obo:IAO_0000118>
        <obo:IAO_0000119>Bjoern Peters</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0001938 rdf:resource="http://purl.obolibrary.org/obo/OBI_0001930"/>
        <rdfs:label>categorical measurement datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000968 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000968">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000312"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000968</metadata:prefixIRI>
        <obo:IAO_0000111>device</obo:IAO_0000111>
        <obo:IAO_0000112>A voltmeter is a measurement device which is intended to perform some measure function.</obo:IAO_0000112>
        <obo:IAO_0000112>An autoclave is a device that sterlizes instruments or contaminated waste by applying high temperature and pressure.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A material entity that is designed to perform a function in a scientific investigation, but is not a reagent.</obo:IAO_0000115>
        <obo:IAO_0000116>2012-12-17 JAO: In common lab usage, there is a distinction made between devices and reagents that is difficult to model. Therefore we have chosen to specifically exclude reagents from the definition of &quot;device&quot;, and are enumerating the types of roles that a reagent can perform.

2013-6-5 MHB: The following clarifications are outcomes of the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions.  Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear.  For example:

(1) An HPLC machine is considered a device, but has a column that holds a stationary phase resin as an operational component.  This resin qualifies as a device if it participates purely in size exclusion, but bears a reagent role that is realized in the running of a column if it interacts electrostatically or chemically with the evaluant. The container the resin is in (“the column”) considered alone is a device. So the entire column as well as the entire HPLC machine are devices that have a reagent as an operating part.

(2) A pH meter is a device, but its electrode component bears a reagent role in virtue of its interacting directly with the evaluant in execution of an assay.

(3) A gel running  box  is a device that has a metallic lead as a component that participates in a chemical reaction with the running buffer when a charge is passed through it.  This metallic lead is considered to have a reagent role as a component of this device realized in the running of a gel.

In the examples above, a reagent is an operational component of a device, but the device itself does not realize a reagent role (as bearing a reagent role is not transitive across the part_of relation).  In this way, the asserted disjointness between a reagent and device holds, as both roles are never realized in the same bearer during execution of an assay.</obo:IAO_0000116>
        <obo:IAO_0000117>PERSON: Helen Parkinson</obo:IAO_0000117>
        <obo:IAO_0000118>instrument</obo:IAO_0000118>
        <obo:IAO_0000119>OBI development call 2012-12-17.</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0000312 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000094"/>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
        <rdfs:label>device</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000969 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000969">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000969</metadata:prefixIRI>
        <obo:IAO_0000111>dose specification</obo:IAO_0000111>
        <obo:IAO_0000112>a protocol specifying to administer 1 ml of vaccine to a mouse</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">a directive information entity that describes the dose that will be administered to a target</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>dose specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000984 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000984">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0000984</metadata:prefixIRI>
        <obo:IAO_0000111>dose</obo:IAO_0000111>
        <obo:IAO_0000112>An organism has been injected 1ml of vaccine</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>dose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0001930 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001930">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001933"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0001930</metadata:prefixIRI>
        <obo:IAO_0000111>categorical value specification</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">A value specification that is specifies one category out of a fixed number of nominal categories</obo:IAO_0000115>
        <obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>categorical value specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0001933 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001933">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0001933</metadata:prefixIRI>
        <obo:IAO_0000111>value specification</obo:IAO_0000111>
        <obo:IAO_0000112>The value of &apos;positive&apos; in a classification scheme of &quot;positive or negative&quot;; the value of &apos;20g&apos; on the quantitative scale of mass.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">An information content entity that specifies a value within a classification scheme or on a quantitative scale.</obo:IAO_0000115>
        <obo:IAO_0000116>This term is currently a descendant of &apos;information content entity&apos;, which requires that it &apos;is about&apos; something. A value specification of &apos;20g&apos; for a measurement data item of the mass of a particular mouse &apos;is about&apos; the mass of that mouse. However there are cases where a value specification is not clearly about any particular. In the future we may change &apos;value specification&apos; to remove the &apos;is about&apos; requirement.</obo:IAO_0000116>
        <obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>value specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0003456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003456">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0003456</metadata:prefixIRI>
        <obo:IAO_0000111>in vivo challenge</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">The administration of a challenge to a live host.</obo:IAO_0000115>
        <obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
        <obo:IAO_0000119>IEDB</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>in vivo challenge</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0003610 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0003610">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0003610</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">reactant role</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">A role borne by a biological or chemical entity that participates or has molecular components that participate in a chemical reaction.</obo:IAO_0000115>
        <obo:IAO_0000117>Sebastian Duesing</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">reactant role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0100026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100026">
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2157"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0100026</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">organism</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">animal</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">fungus</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">plant</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">virus</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.</obo:IAO_0000115>
        <obo:IAO_0000116>10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and &apos;other organisms&apos;)</obo:IAO_0000116>
        <obo:IAO_0000116>13-02-2009:
OBI doesn&apos;t take position as to  when an organism starts or ends being an organism - e.g. sperm, foetus.
This issue is outside the scope of OBI.</obo:IAO_0000116>
        <obo:IAO_0000117>GROUP: OBI Biomaterial Branch</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Organism</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">organism</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0100046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100046">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302729"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000576"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
                                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_26710"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000576"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000643"/>
                                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_37586"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302731"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0100046</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">phosphate buffered saline solution</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PMID: 16279733.Dent Mater J. 2005 Sep;24(3):414-21.PBS buffer solutions with different pH values can change porosity of DNA-chitosan complexes.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">Phosphate buffered saline (abbreviated PBS) is a buffer solution commonly used in biochemistry. It is a salty solution containing sodium chloride, sodium phosphate and in some preparations potassium chloride and potassium phosphate. The buffer helps to maintain a constant pH. The concentration usually matches the human body (isotonic).</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Tina Boussard</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">PBS buffer</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">WEB: http://en.wikipedia.org/wiki/Phosphate_buffered_saline</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/OBI_0302731"/>
        <rdfs:label xml:lang="en">phosphate buffered saline solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0200000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200000">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0200166"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000064"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0200000</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">data transformation</obo:IAO_0000111>
        <obo:IAO_0000112>The application of a clustering protocol to microarray data or the application of a statistical testing method on a primary data set to determine a p-value.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that produces output data from input data.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elisabetta Manduchi</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Helen Parkinson</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Richard Scheuermann</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Ryan Brinkman</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Tina Hernandez-Boussard</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">data analysis</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">data processing</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">Branch editors</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">data transformation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0200166 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200166">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0200166</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">data transformation objective</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">normalize objective</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">An objective specification to transformation input data into output data</obo:IAO_0000115>
        <obo:IAO_0000116>Modified definition in 2013 Philly OBI workshop</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">James Malone</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">PERSON: James Malone</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">data transformation objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0200201 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0200201">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000673"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0200201</metadata:prefixIRI>
        <obo:IAO_0000111>ANOVA</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">A statistical hypothesis test in which the means of several groups are all equal.</obo:IAO_0000115>
        <obo:IAO_0000117>James Malone</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>ANOVA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0302729 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302729">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000576"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302732"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000576"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0302733"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0302729</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">chemical solution</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PMID: 18289311.Anesth Analg. 2008 Apr;106(4):1078-86.Less impairment of hemostasis and reduced blood loss in pigs after resuscitation from hemorrhagic shock using the small-volume concept with hypertonic saline/hydroxyethyl starch as compared to administration of 4% gelatin or 6% hydroxyethyl starch solution.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A material entity  that is made up of at least 2 scattered molecular aggregates, one playing the role of solvent and the other one playing the role of solute.</obo:IAO_0000115>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">liquid chemical solution</obo:IAO_0000118>
        <obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">chemical solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0302731 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302731">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0302731</metadata:prefixIRI>
        <obo:IAO_0000111>buffer role</obo:IAO_0000111>
        <obo:IAO_0000112>A buffer of carbonic acid (H2CO3) and bicarbonate (HCO3-) is present in blood plasma, to maintain a pH between 7.35 and 7.45. http://en.wikipedia.org/wiki/Buffer_solution</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">a role which inheres in some molecular entity realized during the process of buffering</obo:IAO_0000115>
        <obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
        <obo:IAO_0000117>Person:Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000118>buffer</obo:IAO_0000118>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">buffer role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0302732 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302732">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0003610"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000685"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0302732</metadata:prefixIRI>
        <obo:IAO_0000111>solvent role</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PMID: 18373502.Transfusion. 2008 Mar 25. Solvent/detergent treatment of platelet concentrates enhances the release of growth factors.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">solvent role is a role which inheres in a molecular entity capable of ensuring the dissolution of another chemical entity and realized by the process of solvation</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">The class CHEBI:solvent is logically equivalent to this class, iff it is properly subsumed under the BFO:role branch. The label and textual definition of this CHEBI class are however misleadingly denoting the material entity that bears this role and not the role itself. The OBI modeling was needed as what is considered a solvent in a mixture can depend on the intent of the person creating the mixture. It would be great if this could be dealt with in CHEBI itself. See also https://github.com/obi-ontology/obi/issues/1771.</obo:IAO_0000116>
        <obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000119>adpated from wikipedia (http://en.wikipedia.org/wiki/Solvatation)</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:RO_0000052 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <rdfs:label xml:lang="en">solvent role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0302733 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302733">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000685"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0302733</metadata:prefixIRI>
        <obo:IAO_0000111>solute role</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PMID: 18380397.Pharmazie. 2008 Feb;63(2):113-21.Deviations of drug solubility in water-cosolvent mixtures from the Jouyban-Acree model--effect of solute structure.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">solute role is a role played by a chemical entity which is dissolved by another chemical entity (the solvent) when creating a solution</obo:IAO_0000115>
        <obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000119>adapted from wikipedia (http://en.wikipedia.org/wiki/Solute)</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:RO_0000052 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <rdfs:label xml:lang="en">solute role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0302893 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0302893">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000806"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0302893</metadata:prefixIRI>
        <obo:IAO_0000111>storage</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">PMID: 18550121.Total Prostate Specific Antigen Stability Confirmed After Long-Term Storage of Serum at -80C. J Urol. 2008 Jun 10.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A planned process with the objective to preserve and protect material entities by placing them in an identified location which may have a controlled environment.</obo:IAO_0000115>
        <obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
        <obo:IAO_0000119>OBI-Branch</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <obo:OBI_0000293 rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <obo:OBI_0000417 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000806"/>
        <rdfs:label xml:lang="en">storage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0500000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0500000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000272"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0500000</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000272"/>
        <obo:IAO_0000111 xml:lang="en">study design</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">a matched pairs study design describes criteria by which subjects are identified as pairs which then undergo the same protocols, and the data generated is analyzed by comparing the differences between the paired subjects, which constitute the results of the executed study design.</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.</obo:IAO_0000115>
        <obo:IAO_0000116>Editor note: there is at least an implicit restriction on the kind of data transformations that can be done based on the measured data available.</obo:IAO_0000116>
        <obo:IAO_0000117>PERSON: Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">experimental design</obo:IAO_0000118>
        <obo:IAO_0000232 xml:lang="en">rediscussed at length (MC/JF/BP). 12/9/08). The definition was clarified to differentiate it from protocol.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">study design</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0600007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0600007">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000319"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
                                        <owl:someValuesFrom>
                                            <owl:Class>
                                                <owl:unionOf rdf:parseType="Collection">
                                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
                                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000465"/>
                                                </owl:unionOf>
                                            </owl:Class>
                                        </owl:someValuesFrom>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:0600007</metadata:prefixIRI>
        <obo:IAO_0000111 xml:lang="en">administering substance in vivo</obo:IAO_0000111>
        <obo:IAO_0000112>Balb/c mice received an intracameral or subconjunctival injection of trinitrophenylated spleen cells</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">injecting mice with 10 ug morphine intranasally, a patient taking two pills of 1 mg aspirin orally</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">A process by which a substance is intentionally given to an organism resulting in exposure of the organism to that substance.</obo:IAO_0000115>
        <obo:IAO_0000116>2009-11-10. Tracker: https://sourceforge.net/tracker/?func=detail&amp;aid=2893050&amp;group_id=177891&amp;atid=886178</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Different routes and means of administration should go as children underneath this</obo:IAO_0000116>
        <obo:IAO_0000116>Update the definition based on the discussion. Details see the tracker:
https://sourceforge.net/p/obi/obi-terms/738/</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">needs roles such as perturber and perturbee (children of input role). Perturb is too strong. Host might be the name for one role. Others considered: Doner, Donated, Acceptor.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">administering substance in vivo</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OBI_1110034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_1110034">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000237"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OBI:1110034</metadata:prefixIRI>
        <obo:IAO_0000111>antigen</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
        <obo:IAO_0000115 xml:lang="en">A material entity that has the antigen role.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">IEDB</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">IEDB</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_0000000002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_0000000002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:0000000002</metadata:prefixIRI>
        <obo:IAO_0000115>A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/books/NBK21640/</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <rdfs:label xml:lang="en">gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_2000000002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_2000000002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_0000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:2000000002</metadata:prefixIRI>
        <obo:IAO_0000115>A gene of an organism of Bacteria</obo:IAO_0000115>
        <obo:IAO_0000117>Yue Liu, Bin Zhao, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000015>2</obo:OGG_0000000015>
        <rdfs:label>gene of Bacteria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_2000001224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_2000001224">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:2000001224</metadata:prefixIRI>
        <obo:IAO_0000115>A gene of an organism of Proteobacteria</obo:IAO_0000115>
        <obo:IAO_0000117>Yue Liu, Bin Zhao, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000015>1224</obo:OGG_0000000015>
        <rdfs:label>gene of Proteobacteria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_2000083332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_2000083332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:2000083332</metadata:prefixIRI>
        <obo:IAO_0000115>A gene of an organism of Mycobacterium tuberculosis H37Rv</obo:IAO_0000115>
        <obo:IAO_0000117>Yue Liu, Bin Zhao, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <rdfs:label>gene of Mycobacterium tuberculosis H37Rv</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_2000224914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_2000224914">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000001224"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:2000224914</metadata:prefixIRI>
        <obo:IAO_0000115>A gene of an organism of Brucella melitensis bv. 1 str. 16M</obo:IAO_0000115>
        <obo:IAO_0000117>Yue Liu, Bin Zhao, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000015>224914</obo:OGG_0000000015>
        <rdfs:label>gene of Brucella melitensis bv. 1 str. 16M</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_2060083332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_2060083332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:2060083332</metadata:prefixIRI>
        <obo:IAO_0000115>A gene of Mycobacterium tuberculosis H37Rv that has a protein-coding gene disposition</obo:IAO_0000115>
        <obo:IAO_0000117>Bin Zhao, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <rdfs:label>protein-coding gene of Mycobacterium tuberculosis H37Rv</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_2060224914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_2060224914">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000224914"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:2060224914</metadata:prefixIRI>
        <obo:IAO_0000115>A gene of Brucella melitensis bv. 1 str. 16M that has a protein-coding gene disposition</obo:IAO_0000115>
        <obo:IAO_0000117>Bin Zhao, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000015>224914</obo:OGG_0000000015>
        <rdfs:label>protein-coding gene of Brucella melitensis bv. 1 str. 16M</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000885459 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000885459">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000885459</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>885459</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv3602c</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140405</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 20980199</obo:OGG_0000000030>
        <dc:description>Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme)</dc:description>
        <rdfs:label>panC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000885594 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000885594">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000885594</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>885594</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv1821</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140329</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 17030572; 18487341; 19240020; 20980199; 24297168</obo:OGG_0000000030>
        <dc:description>Possible preprotein translocase ATPase SecA2</dc:description>
        <rdfs:label>secA2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000885596 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000885596">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000885596</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>885596</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv3601c</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140405</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 20980199</obo:OGG_0000000030>
        <dc:description>Probable aspartate 1-decarboxylase precursor PanD (aspartate alpha-decarboxylase)</dc:description>
        <rdfs:label>panD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000886960 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000886960">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000886960</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>886960</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv1293</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140405</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 16511157; 19543810; 20980199</obo:OGG_0000000030>
        <dc:description>Diaminopimelate decarboxylase LysA (DAP decarboxylase)</dc:description>
        <rdfs:label>lysA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000887603 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000887603">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000887603</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>887603</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv2930</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140322</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 15749014; 20553505; 20980199</obo:OGG_0000000030>
        <dc:description>Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)</dc:description>
        <rdfs:label>fadD26</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000887681 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000887681">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000887681</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>887681</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv2192c</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140405</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 16337227; 20980199; 23363292</obo:OGG_0000000030>
        <dc:description>Probable anthranilate phosphoribosyltransferase TrpD</dc:description>
        <rdfs:label>trpD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000888225 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000888225">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000888225</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>888225</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv2987c</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140405</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 19194004; 20980199</obo:OGG_0000000030>
        <dc:description>Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI)</dc:description>
        <rdfs:label>leuD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000888491 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000888491">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000888491</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>888491</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv2938</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140322</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 20980199</obo:OGG_0000000030>
        <dc:description>Probable daunorubicin-dim-transport integral membrane protein ABC transporter DrrC</dc:description>
        <rdfs:label>drrC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000888751 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000888751">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000888751</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>888751</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv1221</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140406</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 16513743; 18192397; 18606740; 18657035; 20980199</obo:OGG_0000000030>
        <dc:description>Alternative RNA polymerase sigma factor SigE</dc:description>
        <rdfs:label>sigE</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3000888772 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3000888772">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060083332"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3000888772</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>888772</obo:OGG_0000000006>
        <obo:OGG_0000000007>Rv0757</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140322</obo:OGG_0000000009>
        <obo:OGG_0000000015>83332</obo:OGG_0000000015>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 9634230; 12368430; 16573683; 18052041; 18065542; 18065544; 18282096; 18757548; 18946503; 19820095; 20363229; 20814030; 20980199; 21634789; 22072719; 22880126</obo:OGG_0000000030>
        <dc:description>Possible two component system response transcriptional positive regulator PhoP</dc:description>
        <rdfs:label>phoP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGG_3001197075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGG_3001197075">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2060224914"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGG:3001197075</metadata:prefixIRI>
        <obo:IAO_0000117>Bin Zhao, Yue Liu, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/gene</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogg.owl"/>
        <obo:OGG_0000000006>1197075</obo:OGG_0000000006>
        <obo:OGG_0000000007>BMEI1364</obo:OGG_0000000007>
        <obo:OGG_0000000009>20140222</obo:OGG_0000000009>
        <obo:OGG_0000000015>224914</obo:OGG_0000000015>
        <obo:OGG_0000000017>I</obo:OGG_0000000017>
        <obo:OGG_0000000018>protein-coding</obo:OGG_0000000018>
        <obo:OGG_0000000019>NCBI-supplied</obo:OGG_0000000019>
        <obo:OGG_0000000030>PMID: 11756688; 12271122; 23161025</obo:OGG_0000000030>
        <dc:description>transcriptional regulatory protein MUCR</dc:description>
        <rdfs:label>BMEI1364</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGMS_0000060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000060">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGMS:0000060</metadata:prefixIRI>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000232>creation date: 2009-06-23T11:53:49Z</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
        <rdfs:label>bodily process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGMS_0000061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000061">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000060"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGMS:0000061</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">A bodily process that is clinically abnormal.</obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
        <obo:IAO_0000232>creation date: 2009-06-23T11:54:29Z</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
        <rdfs:label>pathological bodily process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OGMS_0000063 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000063">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OGMS:0000063</metadata:prefixIRI>
        <obo:IAO_0000115 xml:lang="en">The totality of all processes through which a given disease instance is realized.</obo:IAO_0000115>
        <obo:IAO_0000117>Albert Goldfain</obo:IAO_0000117>
        <obo:IAO_0000119>http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf</obo:IAO_0000119>
        <obo:IAO_0000232>creation date: 2009-06-23T11:55:44Z</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ogms.owl"/>
        <rdfs:label>disease course</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000004">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0001046"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70999"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001046"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000004</metadata:prefixIRI>
        <obo:IAO_0000115>A hindgut that is a part of or originated from a Triatominae bug.</obo:IAO_0000115>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Triatominae hindgut</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000007">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000119"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000010"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000119"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000007</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>An exflagellated microgametocyte stage in the lifecycle of Plasmodium falciparum that occurs in the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum exflagellated microgametocyte stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum exflagellated microgametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000010">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000143"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000143"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000192"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000291"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000010</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <obo:IAO_0000115>A microgametocyte stage in the Plasmodium falciparum lifecycle that occurs either in the bloodstream of a human host or the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>P. Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan.</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum microgametocyte stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum microgametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000260"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000026</metadata:prefixIRI>
        <obo:IAO_0000115>A gamete stage in apicomplexan parasites when exflagellated microgametocyte divides into microgamete.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Matt Berriman</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
        <rdfs:label>microgamete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000028">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000150"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000028</metadata:prefixIRI>
        <obo:IAO_0000115>A gametocyte stage where a cell differentiates into a female sexual form called macrogametocyte.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>macrogametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000032">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0001045"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7164"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001045"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000032</metadata:prefixIRI>
        <obo:IAO_0000115>A midgut that is a part of or originated from an Anopheles mosquito.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Anopheles midgut</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5690"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000033</metadata:prefixIRI>
        <obo:IAO_0000115>A parasite lifecycle stage of trypanosomes. In trypomastigote stage, the kinetoplast is near the posterior end of the body, and the flagellum lies attached to the cell body for most of its length by an undulating membrane.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>Wikipedia: Trypanosomatid</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5690"/>
        <rdfs:label>trypomastigote stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000035">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000078"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000078"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000158"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000298"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000035</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <obo:IAO_0000115>An erythrocytic schizont stage in the Plasmodium falciparum lifecycle that occurs in the infected erythrocytes of a human host.</obo:IAO_0000115>
        <obo:IAO_0000116>updated according to OPL terms Plasmodium final excel file from C. Janse, S. Khan</obo:IAO_0000116>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum erythorcytic schizont stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum erythrocytic schizont stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000036</metadata:prefixIRI>
        <obo:IAO_0000115>A parasite lifecycle stage of apicomplexan species where a daughter cell, called merozoite is produced from schizont through schizogony.</obo:IAO_0000115>
        <obo:IAO_0000116>adjusted to be more general</obo:IAO_0000116>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarM.htm</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
        <rdfs:label>merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000040">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000182"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000182"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000040</metadata:prefixIRI>
        <obo:IAO_0000115>A hepatocyte that is a part of or originated from a human (Homo sapiens).</obo:IAO_0000115>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>human hepatocyte</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <oboInOwl:hasDbXref>FMA:14515</oboInOwl:hasDbXref>
        <rdfs:label>Homo sapiens hepatocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000042">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000140"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000140"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000207"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000305"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000042</metadata:prefixIRI>
        <obo:IAO_0000115>An erythrocytic ring trophozoite stage in the Plasmodium falciparum life cycle that occurs in erythrocytes of a human host. During this stage some Plasmodium falciparum merozoites undergo asexual reproduction cycle in erythrocytes and form young trophozoites that are referred to as &quot;ring form&quot; due to their morphology.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum erythrocytic ring trophozoite stage</obo:IAO_0000118>
        <obo:IAO_0000119>Wikipedia: Plasmodium falciparum biology</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum erythrocytic ring trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000048 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000048">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5691"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000048</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Trypanosoma brucei.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>T. brucei lifecycle stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Trypanosoma brucei lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000249"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000269"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000010"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000050</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum gametocyte that is a male gametocyte and found in either bloodstream of a human host or midgut of a mosquito vector. The microgametocyte is a precursor cell of the microgamete.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum microgametocyte</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000010"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <rdfs:label>Plasmodium falciparum microgametocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000057 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000057">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000057</metadata:prefixIRI>
        <obo:IAO_0000115>A parasite lifecycle stage of some protozoan parasites that is a non-reproductive, feeding and growing stage.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarT.htm</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
        <rdfs:label>trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000059 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000059">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000059</metadata:prefixIRI>
        <obo:IAO_0000115>A schizont stage that occurs in hepatocyte where sporozoites mature into a schizont.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Matt Berriman</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:11006474</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>hepatic schizont stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000060">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000275"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000158"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000060</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum divides through schizogony. Depending on its location, it is either called hepatic or erythrocytic schizont. The schizont is a dividing stage with 2 or more nuclei.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum schizont</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000158"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <rdfs:label>Plasmodium falciparum schizont</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000068 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000068">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000028"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000028"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000192"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000290"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000068</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <obo:IAO_0000115>A macrogametocyte stage in the Plasmodium falciparum lifecycle that occurs either in the bloodstream of a human host or the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000116>gametocytes are mainly found in the blood</obo:IAO_0000116>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum macrogametocyte stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum macrogametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000073">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000073</metadata:prefixIRI>
        <obo:IAO_0000115>A parasite lifecycle stage of sporozoa consisting of a zygote enclosed by cyst wall.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>Mosby&apos;s Medical Dictionary, 8th edition. � 2009, Elsevier. (http://medical-dictionary.thefreedictionary.com/oocyst)</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
        <rdfs:label>oocyst stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000075">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000085"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000085"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000262"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000287"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000075</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>A macrogamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum macrogamete stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum macrogamete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000078 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000078">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000078</metadata:prefixIRI>
        <obo:IAO_0000115>A schizont stage that occurs in erythrocytes where trophozoites mature into a schizont and schizont produces daughter trophozoites or merozoites.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Matt Berriman</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 11006474</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>erythrocytic schizont stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000084 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000084">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000084</metadata:prefixIRI>
        <obo:IAO_0000115>A parasite lifecycle stage that is the multinucleate stage in the development of some members of the Sarcodina and some sporozoans during schizogony.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>http://medical-dictionary.thefreedictionary.com/schizont</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
        <rdfs:label>schizont stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000085 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000085">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000260"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000085</metadata:prefixIRI>
        <obo:IAO_0000115>A gamete stage in parasites when macrogametocytes produce macrogametes through the process known as gametogenesis.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.tulane.edu/~wiser/malaria/mal_lc.PDF</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
        <rdfs:label>macrogamete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000089 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000089">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000274"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000187"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000089</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum that is a &apos;banana-shaped&apos; form and originates from the round zygote. The ookinete is found in the midgut of a mosquito vector and traverses the midgut wall of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum ookinete</obo:IAO_0000118>
        <obo:IAO_0000119>Wikipedia: Plasmodium falciparum biology</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000187"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium falciparum ookinete</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000093">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000059"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000059"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000158"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000299"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000093</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:IAO_0000115>A hepatic schizont stage in the lifecycle of Plasmodium falciparum that occurs in the infected hepatocytes of a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum hepatic schizont stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum hepatic schizont stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000096">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000232"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000096</metadata:prefixIRI>
        <obo:IAO_0000115>An erythrocyte that is a part of or originated from a human (Homo sapiens).</obo:IAO_0000115>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>human RBC</obo:IAO_0000118>
        <obo:IAO_0000118>human erythrocyte</obo:IAO_0000118>
        <obo:IAO_0000118>human red blood cell</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <oboInOwl:hasDbXref>FMA:62845</oboInOwl:hasDbXref>
        <rdfs:label>Homo sapiens erythrocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000103">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000036"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000036"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000292"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000103</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <obo:IAO_0000115>A merozoite stage in the Plasmodium falciparum lifecycle that occurs in the bloodstream or hepatocytes of a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum merozoite stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000110 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000110">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000060"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000276"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000035"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000110</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum schizont that is found in infected erythrocytes of a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum erythrocytic schizont</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000035"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <rdfs:label>Plasmodium falciparum erythrocytic schizont</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000113 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000113">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000073"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000073"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000113</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>An oocyst stage in the Plasmodium falciparum lifecycle that occurs on the hemocoel side of the midgut of a mosquito vector. During this stage Plasmodium falciparum ookinete invades and escapes midgut wall of mosquito and embed itself onto the exterior of the gut membrane and develop encysted zygote, called oocyst.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum oocyst stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum oocyst stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000115 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000115">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000152"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000300"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000115</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
        <obo:IAO_0000115>A sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Matt Berrimen</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum sporozoite stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000117 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000117">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000320"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000117</metadata:prefixIRI>
        <obo:IAO_0000115>Blood that is part of or originated from a human (Homo sapiens).</obo:IAO_0000115>
        <obo:IAO_0000116>previous def was: blood of human</obo:IAO_0000116>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000118>human blood</obo:IAO_0000118>
        <obo:IAO_0000119>OPL</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Homo sapiens blood</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000143"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000119</metadata:prefixIRI>
        <obo:IAO_0000115>A microgametocyte stage in some apicomplexan parasites where microgametocyte gets matured and form microgamete through the process known as exflagellation.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>exflagellated microgametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000121">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0001044"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7164"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001044"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000121</metadata:prefixIRI>
        <obo:IAO_0000115>A salivary gland that is a part of or originated from an Anopheles mosquito.</obo:IAO_0000115>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Anopheles salivary gland</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000130 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000130">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000270"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000103"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000130</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum that is produced in a schizont, found in the bloodstream of a human host and invades erythrocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum merozoite</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000103"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <rdfs:label>Plasmodium falciparum merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000137 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000137">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000278"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000115"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000137</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum is formed in the oocyst. It migrates to and resides in the salivary glands of the mosquito vector. A distinction is made between oocyst-derived and salivary gland-derived sporozoites. Sporozoites invade hepatocytes in the vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum sporozoite</obo:IAO_0000118>
        <obo:IAO_0000119>Wikipedia: Plasmodium falciparum biology</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000115"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
        <rdfs:label>Plasmodium falciparum sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000138 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000138">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000273"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000113"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000138</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum that oocyst is formed, after traversal of the midgut wall by the ookinete stage, on the hemocoel side of the midgut wall of the mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum oocyst</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000113"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium falciparum oocyst</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000140 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000140">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000243"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000140</metadata:prefixIRI>
        <obo:IAO_0000115>An early trophozoite stage of Plasmodium sp. where a large central vacuole and peripheral nucleus give an appearance of a signet ring.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarR.htm</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>erythrocytic ring trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000143 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000143">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000150"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000143</metadata:prefixIRI>
        <obo:IAO_0000115>A gametocyte stage where a cell differentiates into a male sexual form called microgametocyte.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>microgametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000281"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000251"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000146</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum is a feeding form. The trophozoite stage has only 1 nucleus. Depending on its location, it is either called hepatic or erythrocytic trophozoite.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum trophozoite</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000251"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <rdfs:label>Plasmodium falciparum trophozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000105"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000150</metadata:prefixIRI>
        <obo:IAO_0000115>A life cycle stage where a cell differentiates into male or female sexual forms.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>gametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000152 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000152">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000152</metadata:prefixIRI>
        <obo:IAO_0000115>A parasite lifecycle stage of some sporozoans where cells divide through sporogony producing daughter cells called sporozoites that infect new hosts.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarS.htm</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
        <rdfs:label>sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000153 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000153">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000153</metadata:prefixIRI>
        <obo:IAO_0000115>A parasite lifecycle stage of some sporozoans where motile and elongated zygote is formed by the fertilization of the macrogamete during the sexual reproductive phase of the sporozoan life cycle, specifically the malarial parasite Plasmodium.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>Mosby&apos;s Medical Dictionary, 8th edition. � 2009, Elsevier. (http://medical-dictionary.thefreedictionary.com/ookinete)</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
        <rdfs:label>ookinete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000158 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000158">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000084"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000084"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000297"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000158</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <obo:IAO_0000115>A schizont stage in the Plasmodium falciparum lifecycle that occurs in erythrocytes or in hepatocytes.</obo:IAO_0000115>
        <obo:IAO_0000116>updated according to OPL terms Plasmodium final excel file from C. Janse, S. Khan</obo:IAO_0000116>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum schizont stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum schizont stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000161 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000161">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000285"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000199"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000161</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum zygote is formed after fertilisation of the macrogamete by a microgamete in the midgut of the mosquito vector. This round form is the only diploid stage in the Plasmodium falciparum life cycle.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>P. Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum zygote</obo:IAO_0000118>
        <obo:IAO_0000119>Wikipedia: Plasmodium falciparum biology</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000199"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium falciparum zygote</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000162">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000050"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000007"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000162</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum microgametocyte that is matured with flagellated motile microgametes still attached to its central body. Exflagellated microgametocyte of Plasmodium falciparum is found in the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Matt Berriman</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum exflagellated microgametocyte</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000007"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium falciparum exflagellated microgametocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000164 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000164">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000169"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000004"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000321"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000164</metadata:prefixIRI>
        <obo:IAO_0000115>A Trypanosoma cruzi that is found in the bloodstream of infected mammals. It is a non-dividing form that is infectious for its insect vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi trypomastigote</obo:IAO_0000118>
        <obo:IAO_0000119>http://dna.kdna.ucla.edu/parasite_course-old/cruzi_files/intro.htm</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000169"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000004"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000320"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000321"/>
        <rdfs:label>Trypanosoma cruzi trypomastigote</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000165 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000165">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000165</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Plasmodium falciparum.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum lifecycle stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000167 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000167">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000265"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000075"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000167</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum gamete that is a matured form of the macrogametocyte and is found in the midgut of a mosquito vector. The macrogamete is fertilized by the microgamete, forming the zygote</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum macrogamete</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000075"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium falciparum macrogamete</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000169 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000169">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000033"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000033"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000185"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000004"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000321"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000169</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000004"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000320"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000321"/>
        <obo:IAO_0000115>A trypomastigote stage in the Trypanosoma cruzi lifecycle that occurs either in the vertebrate host or an insect vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi trypomastigote stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Trypanosoma cruzi trypomastigote stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000170 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000170">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000026"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000026"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000262"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000288"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000170</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>A microgamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum microgamete stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum microgamete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000171 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000171">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IDO_0000403"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000171</metadata:prefixIRI>
        <obo:IAO_0000115>A parasite role which is realized only during parasitic infection of a human.</obo:IAO_0000115>
        <obo:IAO_0000116>previous def was not about a role.</obo:IAO_0000116>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>human parasite role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000174 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000174">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000266"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000170"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000174</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum gamete that is a matured form of exflagellated microgametocyte and found in the midgut of a mosquito vector. The microgamete fertilizes the macrogamete, forming the zygote.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum microgamete</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000170"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium falciparum microgamete</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000175 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000175">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000033"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5691"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000033"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000048"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000175</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000313"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000320"/>
        <obo:IAO_0000115>A trypomastigote stage in the Trypanosoma brucei lifecycle that occurs in the vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>T. brucei trypomastigote stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Trypanosoma brucei trypomastigote stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000181">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000105"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000232"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000105"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000181</metadata:prefixIRI>
        <obo:IAO_0000115>A life cycle stage of a parasite.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>parasite lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5691"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000175"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000182</metadata:prefixIRI>
        <obo:IAO_0000115>A Trypanosoma brucei that is a Trypomastigote form of Trypanosoma brucei. In this form the large kinetoplast is postnuclear and is at the most posterior part of the body and the flagellum emerges from the flagellar pocket, and runs along the entire length of the body as an undulating membrane.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>T. brucei trypomastigote</obo:IAO_0000118>
        <obo:IAO_0000119>http://dna.kdna.ucla.edu/parasite_course-old/african%20tryps%20new_files/contents1.htm</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000175"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000313"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000320"/>
        <rdfs:label>Trypanosoma brucei trypomastigote</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000185">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000185</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Trypanosoma cruzi.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi lifecycle stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Trypanosoma cruzi lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000187 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000187">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000153"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000153"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000296"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000187</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>An ookinete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector and on the outside of the midgut.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum ookinete stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum ookinete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000190 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000190">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000060"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000277"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000093"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000190</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum schizont that is found in infected hepatocytes (i.e., liver cells) of a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum hepatic schizont</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000093"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <rdfs:label>Plasmodium falciparum hepatic schizont</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000192">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000150"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000150"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000289"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000192</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <obo:IAO_0000115>A gametocyte stage in the lifecycle of Plasmodium falciparum.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum gametocyte stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum gametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000199 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000199">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000106"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000307"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000106"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000199</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>A zygote stage in the Plasmodium falciparum lifecycle that occurs in the midgut of the mosquito vector where a microgamete and a macrogamete fertilizes each other to produce a diploid cell.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum zygote stage</obo:IAO_0000118>
        <obo:IAO_0000119>Wikipedia: Plasmodium falciparum biology</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum zygote stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000206 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000206">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000249"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000268"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000068"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000206</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum gametocyte that is a female gametocyte and found either in bloodstream of a human host or midgut of mosquito vector. The macrogametocyte is a precursor of the macrogamete.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum macrogametocyte</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000068"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <rdfs:label>Plasmodium falciparum macrogametocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000207 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000207">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000243"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000243"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000251"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000304"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000207</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <obo:IAO_0000115>An erythrocytic trophozoite stage in the Plasmodium falciparum life cycle that occurs in erythrocytes of a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum erythrocytic trophozoite stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum erythrocytic trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000222 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000222">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000244"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000283"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000042"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000222</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum erythrocytic trophozoite that is found in erythrocytes. It is a young trophozoite stage that has a typical &apos;ring-like&apos; appearance. Ring-form trophozoites of Plasmodium falciparum are often thin and delicate, measuring on average 1/5 the diameter of the red blood cell.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parkh</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum erythrocytic ring trophozoite</obo:IAO_0000118>
        <obo:IAO_0000119>http://www.dpd.cdc.gov/dpdx/html/frames/m-r/malaria/falciparum/body_malariadffalcring.htm</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000042"/>
        <rdfs:label>Plasmodium falciparum erythrocytic ring trophozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000232">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/IDO_0000403"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000232</metadata:prefixIRI>
        <obo:IAO_0000115>An organism living in, with, or on another organism in parasitism. Individual members of parasite species, such as Leishmania, Plasmodium, Trypanosoma, etc. are members of this class.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Priti Parikh</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.merriam-webster.com/dictionary/parasite?show=0&amp;t=1310398415</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>parasite organism</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000272"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000246"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000241</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum merozoite that is produced in a hepatic schizont and released into the bloodstream of a human host. These forms invade erythrocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum hepatic merozoite</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000246"/>
        <rdfs:label>Plasmodium falciparum hepatic merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000271"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000245"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000242</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum merozoite that is produced in an erythrocytic schizont and released into the bloodstream of a human host. These forms invade erythrocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum erythrocytic merozoite</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000245"/>
        <rdfs:label>Plasmodium falciparum erythrocytic merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000243 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000243">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000057"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000243</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
        <obo:IAO_0000115>A trophozoite stage in some protozoan parasite life cycle that occurs in erythrocytes.</obo:IAO_0000115>
        <obo:IAO_0000116>definition adapted from that for P. falciparum erythrocytic trophozoite stage and parent trophozoite stage</obo:IAO_0000116>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>erythrocytic trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000146"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000282"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000207"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000244</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum trophozoite that is found in erythrocytes. It is a feeding stage with a single nucleus.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum erythrocytic trophozoite</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000207"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <rdfs:label>Plasmodium falciparum erythrocytic trophozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000245">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000248"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000103"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000248"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000293"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000245</metadata:prefixIRI>
        <obo:IAO_0000115>An erythrocytic merozoite stage in the Plasmodium falciparum lifecycle that occurs in the bloodstream of a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum erythrocytic merozoite stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum erythrocytic merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000246 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000246">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000247"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000103"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000247"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000294"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000246</metadata:prefixIRI>
        <obo:IAO_0000115>A hepatic merozoite stage in the Plasmodium falciparum lifecycle that occurs in the hepatocyte of a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum hepatic merozoite stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum hepatic merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000247 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000247">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000036"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000182"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000247</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/CL_0000182"/>
        <obo:IAO_0000115>A merozoite stage in the Plasmodium lifecycle that occurs in the hepatocyte of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000116>definition adapted from that for P. falciparum hepatic merozoite stage</obo:IAO_0000116>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>hepatic merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000248 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000248">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000036"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000248</metadata:prefixIRI>
        <obo:IAO_0000115>A merozoite stage in the apicomplexan lifecycle that occurrs in the bloodstream of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000116>definition adapted from that for P. falciparum salivary erythrocytic merozoite stage and from the general merozoite definition</obo:IAO_0000116>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>erythrocytic merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000249 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000249">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000267"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000192"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000249</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum that is located either in the bloodstream of the human host or midgut of mosquito vector. Gametocytes are the precursor cells of the macro- or micro-gametes.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>K. Louis</obo:IAO_0000117>
        <obo:IAO_0000117>S Khan</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000192"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <rdfs:label>Plasmodium falciparum gametocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000250">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000261"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000251"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000261"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000306"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000250</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:IAO_0000115>A hepatic trophozoite stage in the Plasmodium falciparum life cycle that occurs in hepatocytes of a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum hepatic trophozoite stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum hepatic trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000251 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000251">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000057"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000057"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000303"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000251</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <obo:IAO_0000115>A trophozoite stage in the Plasmodium falciparum lifecycle that occurs in a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum trophozoite stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000252 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000252">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000256"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000115"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000256"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000301"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000252</metadata:prefixIRI>
        <obo:IAO_0000115>A sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum oocyst-derived sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000253 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000253">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001044"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000253</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001044"/>
        <obo:IAO_0000115>A sporozoite stage in the Plasmodium lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000116>definition adapted from that for P. falciparum salivary gland derived sporozoite stage</obo:IAO_0000116>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>salivary gland-derived sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000254 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000254">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000253"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000115"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000253"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000302"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000254</metadata:prefixIRI>
        <obo:IAO_0000115>A salivary gland-derived sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum salivary gland-derived sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000280"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000254"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000255</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum sporozoite that is formed in the oocyst. It migrates to and resides in the salivary glands of the mosquito vector. Sporozoites invade hepatocytes in a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum salivary gland-derived sporozoite</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000254"/>
        <rdfs:label>Plasmodium falciparum salivary gland-derived sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000256 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000256">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000256</metadata:prefixIRI>
        <obo:IAO_0000115>A sporozoite stage in some parasite lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000116>definition adapted from that for P. falciparum oocyte derived sporozoite stage</obo:IAO_0000116>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>oocyst-derived sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000257 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000257">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000146"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000284"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000250"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000257</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum trophozoite that is found in hepatocytes of a human host. It is a feeding stage with a single nucleus</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum hepatic trophozoite</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000250"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <rdfs:label>Plasmodium falciparum hepatic trophozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000258 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000258">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000264"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000262"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000258</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum that is found in midgut of mosquito vector. There are two forms of gametes: micro- and macrogametocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum gamete</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000262"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium falciparum gamete</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000259 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000259">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000279"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000252"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000259</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum sporozoite that is found in the infected hepatocytes of a human host.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum oocyst-derived sporozoite</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000252"/>
        <rdfs:label>Plasmodium falciparum oocyst-derived sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000260 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000260">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000105"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000260</metadata:prefixIRI>
        <obo:IAO_0000115>A life cycle stage of some parasites that develop into mature sexual cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>gamete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000261">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000057"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000182"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000261</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/CL_0000182"/>
        <obo:IAO_0000115>A trophozoite stage in some protozoan parasite life cycle that occurs in hepatocytes.</obo:IAO_0000115>
        <obo:IAO_0000116>definition adapted from that for P. falciparum hepatic trophozoite stage and from parent trophozoite stage</obo:IAO_0000116>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>hepatic trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000262 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000262">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000260"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5833"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000260"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000286"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000262</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>A gamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>C. Janse</obo:IAO_0000117>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>S. Khan</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum gamete stage</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium falciparum gamete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000264 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000264">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000260"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000264</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium that is found in the midgut of a mosquito vector during gamete lifecycle stage. There are two forms of gametes: micro- and macrogametocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium gamete</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000265 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000265">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000085"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000264"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000265</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium gamete that is in a matured form of the macrogametocyte and found in the midgut of a mosquito vector. The macrogamete is fertilized by the microgamete, forming the zygote.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium macrogamete</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000266 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000266">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000026"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000264"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000266</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium gamete that is in a matured form of exflagellated microgametocyte and found in the midgut of a mosquito vector. The microgamete fertilises the macrogamete, forming the zygote.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium microgamete</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000267 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000267">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000150"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000267</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium that is located either in the bloodstream of the vertebrate host or midgut of mosquito vector during gametocyte stage. Gametocytes are the precursor cells of the macro- or microgametes</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium gametocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000268 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000268">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000028"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000267"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000268</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium gametocyte that is a female gametocyte of Plasmodium and found either in the bloodstream of the vertebrate host or midgut of mosquito vector. The macrogametocyte is a precursor of the macrogamete.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <rdfs:label>Plasmodium macrogametocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000269 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000269">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000143"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000267"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000269</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium gametocyte that is a male gametocyte of Plasmodium and found either in the bloodstream of a vertebrate host or midgut of a mosquito vector. The microgametocyte is a precursor cell of the microgamete</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <rdfs:label>Plasmodium microgametocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000270 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000270">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000036"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000270</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium that is during merozoite lifecycle stage, occurs in the bloodstream of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000271 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000271">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000248"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000270"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000271</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium merozoite that is produced in an erythrocytic schizont and released into the bloodstream of a vertebrate host. These forms invade erythrocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium erythrocytic merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000272">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000247"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000270"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000272</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium merozoite that is produced in a hepatic schizont and released into the bloodstream of a vertebrate host. These forms invade erythrocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium hepatic merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000273">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000073"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000273</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium that is formed after traversal of the midgut wall by the ookinete stage, on the hemocoel side of the midgut wall of the mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium oocyst</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000274 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000274">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000153"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000274</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium that is a &apos;banana-shaped&apos; form originates from the round zygote. The ookinete is found in the midgut of a mosquito vector and traverses the midgut wall of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium ookinete</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000275 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000275">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000084"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000275</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium that is a form divides through schizogony. Depending on its location, it is either called hepatic or erythrocytic schizont. The schizont is a dividing stage with 2 or more nuclei.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium schizont</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000276 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000276">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000078"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000275"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000276</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium schizont that is found in infected erythrocytes of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <rdfs:label>Plasmodium erythrocytic schizont</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000277 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000277">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000059"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000275"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000277</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium schizont that is found in infected hepatocytes (i.e. liver cells) of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
        <rdfs:label>Plasmodium hepatic schizont</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000278">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000278</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium that is formed in the oocyst and migrates to and reside in the salivary glands of the mosquito vector. A distinction is made between oocyst-derived and salivary gland-derived sporozoites. Sporozoites invade hepatocytes in the vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000310"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
        <rdfs:label>Plasmodium sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000279 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000279">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000256"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000278"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000279</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium sporozoite that is found in the infected hepatocytes of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium oocyst-derived sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000280">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000253"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000278"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000280</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium sporozoite that is found in the salivary glands of the mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium salivary gland-derived sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000281">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000057"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000281</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium that is a feeding form which has a single nucleus during the trophozoite stage. Depending on its location, it is either called hepatic or erythrocytic trophozoite.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
        <rdfs:label>Plasmodium trophozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000282 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000282">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000243"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000281"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000282</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium trophozoite that is found in erythrocytes of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <rdfs:label>Plasmodium erythrocytic trophozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000283 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000283">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000140"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000282"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000283</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium erythrocytic trophozoite that has a typical &apos;ring-like&apos; appearance. Ring-form trophozoites of Plasmodium are often thin and delicate, measuring on average 1/5 the diameter of the red blood cell.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium erythrocytic ring trophozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000284 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000284">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000261"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000281"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000284</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium trophozoite that is found in hepatocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
        <rdfs:label>Plasmodium hepatic trophozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000285 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000285">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000106"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000285</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium that is formed after fertilization of the macrogamete by a microgamete in the midgut of the mosquito vector. This round form is the only diploid stage in the Plasmodium life cycle.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Ulrike Boehme</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/2</obo:IAO_0000233>
        <obo:IAO_0000234>GeneDB</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <rdfs:label>Plasmodium zygote</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000286 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000286">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000260"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000260"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000286</metadata:prefixIRI>
        <obo:IAO_0000115>A gamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium gamete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000287 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000287">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000085"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000085"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000286"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000287</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>A macrogamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium macrogamete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000288 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000288">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000026"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000026"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000286"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000288</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>A microgamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium microgamete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000289 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000289">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000150"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000150"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000289</metadata:prefixIRI>
        <obo:IAO_0000115>A gametocyte stage in the lifecycle of Plasmodium.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium gametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000290 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000290">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000028"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000028"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000289"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000290</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <obo:IAO_0000115>A macrogametocyte stage in the Plasmodium lifecycle that occurs either in the bloodstream of a vertebrate host or the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium macrogametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000291 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000291">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000143"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000143"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000289"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000291</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <obo:IAO_0000115>A microgametocyte stage in the Plasmodium lifecycle that occurs either in the bloodstream of a vertebrate host or the midgut of a mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium microgametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000292">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000036"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000036"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000292</metadata:prefixIRI>
        <obo:IAO_0000115>A merozoite stage in the Plasmodium lifecycle that occurs in the bloodstream or hepatocytes of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000293 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000293">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000248"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000248"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000292"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000293</metadata:prefixIRI>
        <obo:IAO_0000115>An erythrocytic merozoite stage in the Plasmodium lifecycle that occurs in the bloodstream of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium erythrocytic merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000294 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000294">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000247"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000247"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000292"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000294</metadata:prefixIRI>
        <obo:IAO_0000115>A hepatic merozoite stage in the Plasmodium lifecycle that occurs in the hepatocyte of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium hepatic merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000295 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000295">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000073"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000073"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000295</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>An oocyst stage in the Plasmodium lifecycle that occurs on the hemocoel side of the midgut of a mosquito vector. During this stage Plasmodium ookinete invades and escapes midgut wall of mosquito and embed itself onto the exterior of the gut membrane and develop encysted zygote, called oocyst.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium oocyst stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000296 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000296">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000153"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000153"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000296</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>An ookinete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector and on the outside of the midgut.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium ookinete stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000297 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000297">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000084"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000297</metadata:prefixIRI>
        <obo:IAO_0000115>A schizont stage in the Plasmodium lifecycle that occurs in erythrocytes or in hepatocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium schizont stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000298 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000298">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000078"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000078"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000297"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000298</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <obo:IAO_0000115>An erythrocytic schizont stage in the Plasmodium lifecycle that occurs in the infected erythrocytes of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium erythrocytic schizont stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000299 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000299">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000059"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000059"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000297"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000299</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
        <obo:IAO_0000115>A hepatic schizont stage in the Plasmodium lifecycle that occurs in the infected hepatocytes of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium hepatic schizont stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000300 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000300">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000152"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000300</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000310"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
        <obo:IAO_0000115>A sporozoite stage in the Plasmodium lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000301 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000301">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000256"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000256"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000300"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000301</metadata:prefixIRI>
        <obo:IAO_0000115>A sporozoite stage in the Plasmodium lifecycle that develops in oocyst of the mosquito midgut.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Omar harb</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium oocyst-derived sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000302 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000302">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000253"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000253"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000300"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000302</metadata:prefixIRI>
        <obo:IAO_0000115>A salivary gland-derived sporozoite stage in the Plasmodium lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Omar harb</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium salivary gland-derived sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000303 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000303">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000057"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000057"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000303</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
        <obo:IAO_0000115>A trophozoite stage in the Plasmodium lifecycle that occurs in a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000304 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000304">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000243"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000243"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000303"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000304</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <obo:IAO_0000115>An erythrocytic trophozoite stage in the Plasmodium life cycle that occurs in erythrocytes of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium erythrocytic trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000305 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000305">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000140"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000140"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000304"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000305</metadata:prefixIRI>
        <obo:IAO_0000115>An erythrocytic ring trophozoite stage in the Plasmodium life cycle that occurs in erythrocytes of a vertebrate host. During this stage some Plasmodium merozoites undergo asexual reproduction cycle in erythrocytes and form young trophozoites that are referred to as &quot;ring form&quot; due to their morphology.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium erythrocytic ring trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000306 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000306">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000261"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000261"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000303"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000306</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000312"/>
        <obo:IAO_0000115>A hepatic trophozoite stage in the Plasmodium life cycle that occurs in hepatocytes of a vertebrate host.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium hepatic trophozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000307 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000307">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000106"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000106"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000307</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000032"/>
        <obo:IAO_0000115>A zygote stage in the Plasmodium lifecycle that occurs in the midgut of the mosquito vector where a microgamete and a macrogamete fertilizes each other to produce a diploid cell.</obo:IAO_0000115>
        <obo:IAO_0000117>Chris Stoeckert</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium zygote stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000310">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7742"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000310</metadata:prefixIRI>
        <obo:IAO_0000115>Blood that is part of or originated from a vertebrate.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>OPL</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Vertebrate blood</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000311 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000311">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000232"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7742"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000311</metadata:prefixIRI>
        <obo:IAO_0000115>An erythrocyte that is a part of or originated from a vertebrate.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>OPL</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Vertebrate erythrocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000312 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000312">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000182"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7742"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000182"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000312</metadata:prefixIRI>
        <obo:IAO_0000115>A hepatocyte that is a part of or originated from a vertebrate.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>OPL</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Vertebrate hepatocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000313 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000313">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0001359"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40674"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001359"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000313</metadata:prefixIRI>
        <obo:IAO_0000115>Cerebrospinal fluid that is a part of or originated from a mammal.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Mammalia cerebrospinal fluid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000320">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40674"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000310"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000320</metadata:prefixIRI>
        <obo:IAO_0000115>Blood that is part of or originated from a mammalia.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Mammalia blood</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000321 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000321">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000235"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40674"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000235"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000321</metadata:prefixIRI>
        <obo:IAO_0000115>A macrophage that is a part of or originated from a mammalia.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Mammalia macrophage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000325 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000325">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000325</metadata:prefixIRI>
        <obo:IAO_0000115>A parasite lifecycle stage that parasite replicates rapidly within the host cell.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744739/</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>tachyzoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000327 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000327">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5855"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000278"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000348"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000327</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium vivax is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000348"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
        <rdfs:label>Plasmodium vivax sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000328 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000328">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5855"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000270"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000349"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000328</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium vivax that is found in the bloodstream of the human host and invades erythrocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000349"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <rdfs:label>Plasmodium vivax merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000330 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000330">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5821"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000278"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000351"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000330</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium berghei is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000351"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
        <rdfs:label>Plasmodium berghei sporazoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000353"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9611"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000332</metadata:prefixIRI>
        <obo:IAO_0000115>A Neospora caninum that is found intracellular in the intermediate hosts in which asexual replication takes place.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890850/</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000353"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9611"/>
        <rdfs:label>Neospora caninum tachyzoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000336 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000336">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_42890"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000357"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000369"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000336</metadata:prefixIRI>
        <obo:IAO_0000115>A Sarcocystis neurona that is found in the bloodstream of the human host and invades erythrocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/books/NBK574577/</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000357"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000369"/>
        <rdfs:label>Sarcocystis neurona merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000338 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000338">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000359"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40674"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000338</metadata:prefixIRI>
        <obo:IAO_0000115>A Toxoplasma gondii that is formed in tissue in  a host and replicates quickly. This replaces the previous term as .</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>Toxoplasma gondii trophozoite</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000359"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40674"/>
        <rdfs:label>Toxoplasma gondii tachyzoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000348 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000348">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000152"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5855"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000300"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000374"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000348</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
        <obo:IAO_0000115>A sporozoite stage in Plasmodium vivax life cycle.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium vivax sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000349 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000349">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000036"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5855"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000036"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000292"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000374"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000349</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000096"/>
        <obo:IAO_0000115>A merozoite stage in the Plasmodium vivax life cycle.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium vivax merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000351 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000351">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000152"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5821"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000300"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000375"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000351</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000040"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000117"/>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000121"/>
        <obo:IAO_0000115>A sporozoite stage in the Plasmodium berghei life cycle.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium berghei sporazoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000353 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000353">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000325"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000325"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000376"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9611"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000353</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9611"/>
        <obo:IAO_0000115>A tachyzoite stage in the Neospora caninum life cycle.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890850/</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Neospora caninum tachyzoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000357 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000357">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000036"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_42890"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000036"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000379"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000369"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000357</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000369"/>
        <obo:IAO_0000115>A merozoite stage in the Sarcocystis neurona life cycle.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://wcvm.usask.ca/learnaboutparasites/parasites/sarcocystis-neurona.php</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Sarcocystis neurona merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000359">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000325"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000325"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000380"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40674"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000359</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40674"/>
        <obo:IAO_0000115>A tachyzoite stage in the Toxoplasma gondii life cycle.</obo:IAO_0000115>
        <obo:IAO_0000116>Tachyzoites can be found in various organs and tissues during the acute phase of Toxoplasma gondii infection, including lymph nodes, spleen, liver, lungs, and the central nervous system. </obo:IAO_0000116>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/21</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Toxoplasma gondii tachyzoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000369 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000369">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000232"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000369</metadata:prefixIRI>
        <obo:IAO_0000115>An erythrocyte that is a part of or originated from a Canis lupus familiaris.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Canis lupus familiaris erythrocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000374 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000374">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5855"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000374</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Plasmodium vivax.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium vivax lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000375 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000375">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5821"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000375</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Plasmodium berghei.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium berghei lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000376 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000376">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000376</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Neospora caninum.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Neospora caninum lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000379 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000379">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_42890"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000379</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Sarcocystis neurona.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Sarcocystis neurona lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000380 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000380">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000380</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Toxoplasma gondii.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Toxoplasma gondii lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000385">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000278"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000400"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000385</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium yoelii in sporozoite stage.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000400"/>
        <rdfs:label>Plasmodium yoelii sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000386">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000270"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000401"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000386</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium yoelii in merozoite stage.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000401"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
        <rdfs:label>Plasmodium yoelii merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000387 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000387">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000267"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000402"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000387</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium yoelii in gametocyte stage.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000402"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
        <rdfs:label>Plasmodium yoelii gametocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000389 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000389">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5825"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000278"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000404"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000389</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium chabaudi in sporozoite stage.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000404"/>
        <rdfs:label>Plasmodium chabaudi sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000393 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000393">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5850"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000278"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000408"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000393</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium knowlesi in sporozoite stage.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000408"/>
        <rdfs:label>Plasmodium knowlesi sporozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000394 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000394">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5850"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000270"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000409"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000394</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium knowlesi in merozoite stage.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <obo:RO_0000056 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000409"/>
        <obo:RO_0001025 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
        <rdfs:label>Plasmodium knowlesi merozoite</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000400 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000400">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000152"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000300"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000415"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000400</metadata:prefixIRI>
        <obo:IAO_0000115>A sporozoite stage in the Plasmodium yoelii.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium yoelii sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000401 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000401">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000036"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000036"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000292"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000401</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
        <obo:IAO_0000115>A merozoite stage in the Plasmodium yoelii.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium yoelii merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000402 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000402">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000150"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000150"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000289"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000402</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
        <obo:IAO_0000115>A gametocyte stage in the Plasmodium yoelii.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium yoelii gametocyte stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000404 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000404">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000152"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5825"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000300"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000416"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000404</metadata:prefixIRI>
        <obo:IAO_0000115>A sporozoite stage in the Plasmodium chabaudi.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium chabaudi sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000408 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000408">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000152"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5850"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000152"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000300"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000417"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000408</metadata:prefixIRI>
        <obo:IAO_0000115>A sporozoite stage in the Plasmodium knowlesi.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium knowlesi sporozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000409 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000409">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000036"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5850"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000036"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000292"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000409</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000414"/>
        <obo:IAO_0000115>A merozoite stage in the Plasmodium knowlesi.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/dpdx/malaria/index.html</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/OPL-ontology/OPL/issues/24</obo:IAO_0000233>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium knowlesi merozoite stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000414 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000414">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000232"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9443"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000311"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000414</metadata:prefixIRI>
        <obo:IAO_0000115>An erythrocyte that is a part of or originated from a primate.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>primate erythrocyte</obo:IAO_0000118>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Primates erythrocyte</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000415 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000415">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000415</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Plasmodium yoelii.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium yoelii lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000416 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000416">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000416</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Plasmodium chabaudi.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium chabaudi lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPL_0000417 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPL_0000417">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OPL_0000181"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5850"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPL_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPL:0000417</metadata:prefixIRI>
        <obo:IAO_0000115>A lifecycle stage of Plasmodium knowlesi.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>He Group</obo:IAO_0000119>
        <obo:IAO_0000234>He Group</obo:IAO_0000234>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opl.owl"/>
        <rdfs:label>Plasmodium knowlesi lifecycle stage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPMI_0000441 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPMI_0000441">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPMI:0000441</metadata:prefixIRI>
        <obo:IAO_0000117>Yingtong Liu, Anthony Huffman, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opmi.owl"/>
        <rdfs:label xml:lang="en">biomarker role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPMI_0000445 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPMI_0000445">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPMI_0000441"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPMI:0000445</metadata:prefixIRI>
        <obo:IAO_0000115>Material entity that has a measurable quality, or that participates in a measurement process profile, which can be used as an indicator of an underlying biological state or identity.</obo:IAO_0000115>
        <obo:IAO_0000116>The NIH Biomarkers and Surrogate Endpoint Working Group defined a biomarker as “A characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention” (https://pubmed.ncbi.nlm.nih.gov/11240971/). However, the definition of &apos;characteriistc&apos; is unclear, so we do not use the exact definintion in the ontology.</obo:IAO_0000116>
        <obo:IAO_0000117>Yingtong Liu, Anthony Huffman, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Biomarker</obo:IAO_0000119>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Biomarker_(cell)</obo:IAO_0000119>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Biomarker_(medicine)</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opmi.owl"/>
        <rdfs:label xml:lang="en">biomarker</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/OPMI_0000446 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OPMI_0000446">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPMI_0000445"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">OPMI:0000446</metadata:prefixIRI>
        <obo:IAO_0000115>Biomarker that has a measurable quality or process profile(s), that can be used as an indicator of an underlying immune state or identity.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>A biomarker that is indicative of an immune response</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/22072636/</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/32286245/</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/opmi.owl"/>
        <rdfs:label xml:lang="en">immune biomarker</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
        <obo:IAO_0000115>A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasAlternativeId>PATO:0000072</oboInOwl:hasAlternativeId>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0000001</oboInOwl:id>
        <rdfs:label>quality</rdfs:label>
        <skos:notation>PATO:0000001</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000165"/>
        <obo:IAO_0000115>A time quality inhering in a bearer by virtue of how long the bearer has existed.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0000011</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#attribute_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#scalar_slim"/>
        <rdfs:label>age</rdfs:label>
        <skos:notation>PATO:0000011</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000044">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000001"/>
        <obo:IAO_0000115>A physical quality which inheres in a bearer by virtue of the number of the bearer&apos;s repetitive actions in a particular time.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0000044</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#attribute_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#scalar_slim"/>
        <rdfs:label>frequency</rdfs:label>
        <skos:notation>PATO:0000044</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
        <obo:IAO_0000115>An organismal quality inhering in a bearer by virtue of the bearer&apos;s ability to undergo sexual reproduction in order to differentiate the individuals or types involved.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0000047</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#attribute_slim"/>
        <rdfs:label>biological sex</rdfs:label>
        <skos:notation>PATO:0000047</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000165 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000165">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
        <obo:IAO_0000115>A quality in which events occur in sequence.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0000165</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#attribute_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#scalar_slim"/>
        <rdfs:label>time</rdfs:label>
        <skos:notation>PATO:0000165</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000169 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000169">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
        <obo:IAO_0000115>An organismal quality inhering in a bearer or a population by virtue of the bearer&apos;s disposition to survive and develop normally or the number of surviving individuals in a given population.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0000169</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#attribute_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#disposition_slim"/>
        <rdfs:label>viability</rdfs:label>
        <skos:notation>PATO:0000169</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000719 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000719">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000169"/>
        <obo:IAO_0000115>A viability quality inhering in a bearer or a population by virtue of the bearer&apos;s ability to survive or the long term survival ability of a given population.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0000719</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#disposition_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#value_slim"/>
        <rdfs:label>viable</rdfs:label>
        <skos:notation>PATO:0000719</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000918 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000918">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
        <obo:IAO_0000115>A 3-D extent quality inhering in a bearer by virtue of the bearer&apos;s amount of 3-dimensional space it occupies.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0000918</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#attribute_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#mpath_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#scalar_slim"/>
        <rdfs:label>volume</rdfs:label>
        <skos:notation>PATO:0000918</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
        <obo:IAO_0000115>A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasAlternativeId>PATO:0002079</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>Wikipedia:Physical_property</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>relational physical quality</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0001018</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#attribute_slim"/>
        <rdfs:label>physical quality</rdfs:label>
        <skos:notation>PATO:0001018</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
        <obo:IAO_0000115>A physical quality inhering in a bearer by virtue of ratio of the bearer&apos;s output to the bearer&apos;s input.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0001029</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#attribute_slim"/>
        <rdfs:label>efficiency</rdfs:label>
        <skos:notation>PATO:0001029</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
        <obo:IAO_0000115>A quality which inheres in a continuant.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasAlternativeId>PATO:0001237</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>PATO:0001238</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>snap:Quality</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>monadic quality of a continuant</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>multiply inhering quality of a physical entity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>quality of a continuant</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>quality of a single physical entity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>quality of an object</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>quality of continuant</oboInOwl:hasExactSynonym>
        <oboInOwl:hasNarrowSynonym>monadic quality of an object</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>monadic quality of continuant</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0001241</oboInOwl:id>
        <rdfs:comment>Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles.</rdfs:comment>
        <rdfs:label>physical object quality</rdfs:label>
        <skos:notation>PATO:0001241</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001422 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001422">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000169"/>
        <obo:IAO_0000115>A viability quality inhering in a bearer by virtue of the cessation of the bearer&apos;s life.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0001422</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#value_slim"/>
        <rdfs:label>dead</rdfs:label>
        <skos:notation>PATO:0001422</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001677 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001677">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001029"/>
        <obo:IAO_0000115>An efficiency quality inhering in a bearer by virtue of the bearer&apos;s lacking efficiency.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <obo:RO_0002604 rdf:resource="http://purl.obolibrary.org/obo/PATO_0001678"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0001677</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#value_slim"/>
        <rdfs:label>inefficient</rdfs:label>
        <skos:notation>PATO:0001677</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001678 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001678">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001029"/>
        <obo:IAO_0000115>An efficiency quality inhering in a bearer by virtue of the bearer&apos;s having efficiency.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <obo:RO_0002604 rdf:resource="http://purl.obolibrary.org/obo/PATO_0001677"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0001678</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#value_slim"/>
        <rdfs:label>efficient</rdfs:label>
        <skos:notation>PATO:0001678</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001995 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001995">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
        <obo:IAO_0000115>A quality that inheres in an entire organism or part of an organism.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0001995</oboInOwl:id>
        <rdfs:label>organismal quality</rdfs:label>
        <skos:notation>PATO:0001995</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0002146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
        <obo:IAO_0000115>A quality inhering in a bearer by virtue of the severity of infectious disease caused by the bearer in a target organism.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0002-2061-091X"/>
        <oboInOwl:creation_date>2009-10-30T05:04:06Z</oboInOwl:creation_date>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0002146</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#attribute_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#scalar_slim"/>
        <rdfs:label>virulence</rdfs:label>
        <skos:notation>PATO:0002146</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0002147 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002147">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002146"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002303"/>
        <obo:IAO_0000115>A virulence that is relatively low.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <obo:RO_0002604 rdf:resource="http://purl.obolibrary.org/obo/PATO_0002148"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0002-2061-091X"/>
        <oboInOwl:creation_date>2009-10-30T05:05:02Z</oboInOwl:creation_date>
        <oboInOwl:hasExactSynonym>attenuated</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0002147</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/pato#value_slim"/>
        <rdfs:label>reduced virulence</rdfs:label>
        <skos:notation>PATO:0002147</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0002303 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002303">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
        <obo:IAO_0000115>A quality of an object that has a value that is decreased compared to normal or average.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pato.owl"/>
        <obo:RO_0002604 rdf:resource="http://purl.obolibrary.org/obo/PATO_0002305"/>
        <terms:contributor rdf:resource="https://orcid.org/0000-0002-2061-091X"/>
        <oboInOwl:creation_date>2011-06-16T06:51:54Z</oboInOwl:creation_date>
        <oboInOwl:hasOBONamespace>quality</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PATO:0002303</oboInOwl:id>
        <rdfs:label>decreased object quality</rdfs:label>
        <skos:notation>PATO:0002303</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000000001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000000001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <obo:IAO_0000115>An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasExactSynonym>natural protein</oboInOwl:hasExactSynonym>
        <oboInOwl:hasNarrowSynonym>native protein</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PR:000000001</oboInOwl:id>
        <rdfs:comment>The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB).</rdfs:comment>
        <rdfs:label>protein</rdfs:label>
        <skos:notation>PR:000000001</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000001096">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
        <obo:IAO_0000115>A protein that has a core domain composition consisting of a signal peptide, an extracellular domain with multiple Leucine rich repeat (Pfam:PF13855) domain (LRR), a cysteine-rich region, a single-pass transmembrane domain and a C-terminal cytoplasmic tail containing a TIR domain (Pfam:PF01582).</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasDbXref>PIRSF:PIRSF800008</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>fam:TLR</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PR:000001096</oboInOwl:id>
        <rdfs:comment>Category=family.</rdfs:comment>
        <rdfs:label>Toll-like receptor</rdfs:label>
        <skos:notation>PR:000001096</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001153 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000001153">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000001096"/>
        <obo:IAO_0000115>A Toll-like receptor that is a translation product of the human TLR2 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasDbXref>IUPHARobj:1752</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>CD282</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>TLR2</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Toll/interleukin-1 receptor-like protein 4</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>TIL4</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>PR:000001153</oboInOwl:id>
        <rdfs:comment>Category=gene.</rdfs:comment>
        <rdfs:label>Toll-like receptor 2</rdfs:label>
        <skos:notation>PR:000001153</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001154 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000001154">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000001096"/>
        <obo:IAO_0000115>A Toll-like receptor that is a translation product of the human TLR3 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasDbXref>IUPHARobj:1753</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>CD283</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>TLR3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PR:000001154</oboInOwl:id>
        <rdfs:comment>Category=gene.</rdfs:comment>
        <rdfs:label>Toll-like receptor 3</rdfs:label>
        <skos:notation>PR:000001154</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001155 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000001155">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000001096"/>
        <obo:IAO_0000115>A Toll-like receptor that is a translation product of the human TLR4 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasBroadSynonym>Toll</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>IUPHARobj:1754</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>CD284</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>TLR4</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Lps</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>PR:000001155</oboInOwl:id>
        <rdfs:comment>Category=gene.</rdfs:comment>
        <rdfs:label>Toll-like receptor 4</rdfs:label>
        <skos:notation>PR:000001155</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001158 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000001158">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000001096"/>
        <obo:IAO_0000115>A Toll-like receptor that is a translation product of the human TLR7 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasDbXref>IUPHARobj:1757</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>TLR7</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>UNQ248/PRO285</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>PR:000001158</oboInOwl:id>
        <rdfs:comment>Category=gene.</rdfs:comment>
        <rdfs:label>Toll-like receptor 7</rdfs:label>
        <skos:notation>PR:000001158</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001159 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000001159">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000001096"/>
        <obo:IAO_0000115>A Toll-like receptor that is a translation product of the human TLR8 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasDbXref>IUPHARobj:1758</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>CD288</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>TLR8</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>UNQ249/PRO286</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>PR:000001159</oboInOwl:id>
        <rdfs:comment>Category=gene.</rdfs:comment>
        <rdfs:label>Toll-like receptor 8</rdfs:label>
        <skos:notation>PR:000001159</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000011271 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000011271">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
        <obo:IAO_0000115>A protein that is a translation product of the human NLRP3 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasDbXref>IUPHARobj:1770</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>CLR1.1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>NLRP3</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>PYRIN-containing APAF1-like protein 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>angiotensin/vasopressin receptor AII/AVP-like</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>caterpiller protein 1.1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>cold autoinflammatory syndrome 1 protein</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>cold autoinflammatory syndrome 1 protein homolog</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>cryopyrin</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>mast cell maturation-associated-inducible protein 1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>C1orf7</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>CIAS1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mmig1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>NALP3</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>PYPAF1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>PR:000011271</oboInOwl:id>
        <rdfs:comment>Category=gene.</rdfs:comment>
        <rdfs:label>NACHT, LRR and PYD domains-containing protein 3</rdfs:label>
        <skos:notation>PR:000011271</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000015399 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000015399">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
        <obo:IAO_0000115>A SODC domain protein that is a translation product of the human SOD1 gene or a 1:1 ortholog thereof.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasExactSynonym>SOD1</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PR:000015399</oboInOwl:id>
        <rdfs:comment>Category=gene.</rdfs:comment>
        <rdfs:label>superoxide dismutase [Cu-Zn]</rdfs:label>
        <skos:notation>PR:000015399</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000050567 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_000050567">
        <obo:IAO_0000115>OBSOLETE. A material entity that minimally consists of a protein.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:consider>PR:000064867</oboInOwl:consider>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:id>PR:000050567</oboInOwl:id>
        <rdfs:comment>Note: Made obsolete since the term definition was much broader than intended. Originally meant to include only single proteins (and derivatives thereof; PR:000000001), protein-containing complexes (GO:0032991), and protein aggregates (PR:000050566), it instead also included cells defined as having certain protein attachments.</rdfs:comment>
        <rdfs:label>obsolete protein-containing material entity</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
        <skos:notation>PR:000050567</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_P0DTC2 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_P0DTC2">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
        <obo:IAO_0000115>A protein that is a translation product of the S gene in SARS-CoV-2.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasDbXref>GenPept:YP_009724390</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UniProtKB:P0DTC2</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>E2 (SARS-CoV-2)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>S (SARS2)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>S glycoprotein (SARS-CoV-2)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>peplomer protein (SARS-CoV-2)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>surface glycoprotein (SARS-CoV-2)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>protein</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>2</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>GU280_gp02</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>S</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>PR:P0DTC2</oboInOwl:id>
        <rdfs:comment>Category=organism-gene. Note: 1273 aa protein. Undergoes additional processing by proteolytic cleavage.</rdfs:comment>
        <rdfs:label>spike glycoprotein (SARS-CoV-2)</rdfs:label>
        <skos:notation>PR:P0DTC2</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_P0DTC4 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/PR_P0DTC4">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004990"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PR:P0DTC4</metadata:prefixIRI>
        <obo:IAO_0000115>Category=organism-gene. Note: 75 aa protein. A protein that is a translation product of the E gene in SARS-CoV-2.</obo:IAO_0000115>
        <obo:IAO_0000118>E (SARS2)</obo:IAO_0000118>
        <obo:IAO_0000118>envelope protein (SARS-CoV-2)</obo:IAO_0000118>
        <obo:IAO_0000118>sM protein (SARS-CoV-2)</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/pr.owl"/>
        <oboInOwl:hasDbXref>UniProtKB:P0DTC4</oboInOwl:hasDbXref>
        <rdfs:label>envelope small membrane protein (SARS-CoV-2)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000062"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004121"/>
        <obo:IAO_0000115>The olfactory organ of vertebrates, consisting of nares, olfactory epithelia and the structures and skeletal framework of the nasal cavity.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000001>Organ that is the specialized structure of the face that contains olfactory neurons. The peripheral olfactory organ is paired[ZFA:0000047].</obo:UBPROP_0000001>
        <obo:UBPROP_0000001>a protuberance in vertebrates that houses the nostrils, or nares, which admit and expel air for respiration in conjunction with the mouth. Behind the nose are the olfactory mucosa and the sinuses. Behind the nasal cavity, air next passes through the pharynx, shared with the digestive system, and then into the rest of the respiratory system. In humans, the nose is located centrally on the face; on most other mammals, it is on the upper tip of the snout[WP]. GO: The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)[Wikipedia:Nose].</obo:UBPROP_0000001>
        <obo:UBPROP_0000001>the organ that is specialized for smell and is part of the respiratory system</obo:UBPROP_0000001>
        <obo:UBPROP_0000008>the structure of the nose varies across vertebrates. In tetrapods the nose is part of the respiratory system.[PMID:25312359]</obo:UBPROP_0000008>
        <oboInOwl:hasDbXref>BTO:0000840</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-2037</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0001274</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:1502</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:16542</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100037</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100370</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:46472</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:77</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000281</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000139</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009666</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000139</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12756</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:181195007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0000047</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0028429</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Nose</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0000047</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Nose</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>nasal sac</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>nose</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>peripheral olfactory organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>nasus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>olfactory apparatus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>proboInOwlscis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0000004</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#major_organ"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>nose</rdfs:label>
        <skos:notation>UBERON:0000004</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/d/d0/Canine-nose.jpg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000042">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004120"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010000"/>
        <obo:IAO_0000115>Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000001>A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000001>a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]</obo:UBPROP_0000001>
        <obo:UBPROP_0000012>in FMA, SM = mesothelium + connective tissue. It excludes the cavity. Serous sac = SM + cavity. Note that the SM is a subtype of wall in FMA.</obo:UBPROP_0000012>
        <dc:contributor rdf:resource="https://github.com/cmungall"/>
        <oboInOwl:hasDbXref>FMA:9581</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:19</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012704</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C13169</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:362878009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0005425</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0036760</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Serous_membrane</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0005425</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>tunica serosa</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>wall of serous sac</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>serosa</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0000042</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>serous membrane</rdfs:label>
        <skos:notation>UBERON:0000042</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png</foaf:depiction>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000061">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
        <obo:IAO_0000115>Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism&apos;s own genome.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33090"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
        <oboInOwl:hasDbXref>AAO:0010825</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>AEO:0000003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BILA:0000003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CARO:0000003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0003003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:00007001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:305751</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:67135</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:781</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HAO:0000003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0003000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D000825</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:362889002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0000037</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TGMA:0001823</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0001759</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0003000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0000037</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>http://dbpedia.org/ontology/AnatomicalStructure</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>biological structure</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>connected biological structure</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0000061</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#common_anatomy"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#upper_level"/>
        <rdfs:label>anatomical structure</rdfs:label>
        <skos:notation>UBERON:0000061</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000062">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010000"/>
        <obo:IAO_0000115>Anatomical structure that performs a specific function or group of functions [WP].</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002161 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_110815"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33090"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
        <obo:UBPROP_0000001>Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.</obo:UBPROP_0000001>
        <obo:UBPROP_0000012>CARO v1 does not include a generic &apos;organ&apos; class, only simple and compound organ. CARO v2 may include organ, see https://github.com/obophenotype/caro/issues/4</obo:UBPROP_0000012>
        <oboInOwl:hasDbXref>BIRNLEX:4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CARO:0020004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000634</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:35949</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ENVO:01000162</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:67498</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0003001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C13018</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:272625005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0178784</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>WBbt:0003760</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Organ_(anatomy)</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>anatomical unit</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>body organ</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>element</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0000062</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#common_anatomy"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#upper_level"/>
        <rdfs:label>organ</rdfs:label>
        <skos:notation>UBERON:0000062</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000064">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010000"/>
        <obo:IAO_0000115>A multicellular structure that is a part of an organ.</obo:IAO_0000115>
        <obo:IAO_0000232>currently defined in a very broad sense, may be replaced by more specific classes in the future</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33090"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
        <oboInOwl:hasDbXref>AAO:0011124</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BIRNLEX:16</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000635</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:82472</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:113343008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:91717005</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>cardinal organ part</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>regional part of organ</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0000064</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#common_anatomy"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#non_informative"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#upper_level"/>
        <rdfs:label>organ part</rdfs:label>
        <skos:notation>UBERON:0000064</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000105 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000105">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
        <obo:IAO_0000115>A spatiotemporal region encompassing some part of the life cycle of an organism.</obo:IAO_0000115>
        <obo:IAO_0000116>this class represents a proper part of the life cycle of an organism. The class &apos;life cycle&apos; should not be placed here</obo:IAO_0000116>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33090"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
        <obo:UBPROP_0000012>the WBls class &apos;all stages&apos; belongs here as it is the superclass of other WBls stages</obo:UBPROP_0000012>
        <obo:UBPROP_0000012>we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage</obo:UBPROP_0000012>
        <oboInOwl:hasDbXref>BILS:0000105</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000399</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBdv:00007012</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:24120</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HsapDv:0000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D008018</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MmusDv:0000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OlatDv:0000010</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PdumDv:0000090</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>WBls:0000002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:1000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFS:0000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFS:0100000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ncithesaurus:Developmental_Stage</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>developmental stage</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym>stage</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0000105</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#common_anatomy"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#upper_level"/>
        <rdfs:label>life cycle stage</rdfs:label>
        <skos:notation>UBERON:0000105</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000106 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000106">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000105"/>
        <obo:IAO_0000115>A stage at which the organism is a single cell produced by means of sexual reproduction.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000003>As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG]</obo:UBPROP_0000003>
        <oboInOwl:hasDbXref>BILS:0000106</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BilaDO:0000005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0001322</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:27</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBdv:00005288</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>IDOMAL:0000302</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12601</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PdumDv:0000100</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000745</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Zygote</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:1000001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFS:0000001</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>1-cell stage</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>fertilized egg stage</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>one cell stage</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>fertilized egg stage</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>one-cell stage</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>zygote</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>zygotum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0000106</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <rdfs:label>zygote stage</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/EMAPA_16033"/>
        <skos:notation>UBERON:0000106</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000165 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000165">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004921"/>
        <obo:IAO_0000115>The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks).</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000001>Cavity in which food is initially ingested and generally contains teeth, tongue and glands.[AAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000003>Molecular and developmental cell lineage data suggest that the acoel mouth opening is homologous to the mouth of protostomes and deuterostomes and that the last common ancestor of the Bilateria (the &apos;urbilaterian&apos;) had only this single digestive opening.[well established][VHOG]</obo:UBPROP_0000003>
        <obo:UBPROP_0000007>oral</obo:UBPROP_0000007>
        <obo:UBPROP_0000011>some AOs place this as developing from the stomodeum but we weaken this to developmental contribution, as the mouth includes non-ectodermal derivatives</obo:UBPROP_0000011>
        <obo:UBPROP_0000012>in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class &apos;oral region&apos; which is part of the mouth, but excludes tongue and lips</obo:UBPROP_0000012>
        <oboInOwl:hasDbXref>AAO:0010355</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0001090</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0004698</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-1315</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000825</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0001326</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:542</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:16262</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:00003126</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:49184</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:75</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000341</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0002474</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000038</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009055</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000038</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:21082005</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TADS:0000040</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0000547</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0000590</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TGMA:0000131</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000280</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000812</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Mouth</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0003029</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0000547</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0000590</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Mouth</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>http://purl.oboInOwllibrary.org/oboInOwl/uberon/images/lamprey_sucker_rosava_3238889218.jpg</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>regio oralis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasNarrowSynonym>adult mouth</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>cavital oralis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>cavitas oris</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>cavum oris</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>mouth cavity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>oral region</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>oral vestibule</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>rima oris</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>stoma</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>stomatodaeum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>trophic apparatus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>vestibule of mouth</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>vestibulum oris</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0000165</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#major_organ"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>mouth</rdfs:label>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/issues/661</rdfs:seeAlso>
        <skos:notation>UBERON:0000165</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/0/06/Mouth_illustration-Otis_Archives.jpg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
        <obo:IAO_0000115>A fluid that is composed of blood plasma and erythrocytes.</obo:IAO_0000115>
        <obo:IAO_0000232>This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:UBPROP_0000001>A complex mixture of cells suspended in a liquid matrix that delivers nutrients to cells and removes wastes. (Source: BioGlossary, www.Biology-Text.com)[TAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000001>Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000002>relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]</obo:UBPROP_0000002>
        <obo:UBPROP_0000003>Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrates phyla. (...) There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast.[well established][VHOG]</obo:UBPROP_0000003>
        <dc:contributor rdf:resource="https://github.com/cmungall"/>
        <dc:contributor rdf:resource="https://github.com/tmeehan"/>
        <oboInOwl:hasDbXref>AAO:0000046</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0000089</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0079</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000296</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0000176</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:418</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:16332</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ENVO:02000027</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100047</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:9670</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:965</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000059</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001769</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000315</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12434</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0000007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0005767</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000224</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Blood</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000124</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0000007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Blood</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>portion of blood</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>vertebrate blood</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>whole blood</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0000178</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>blood</rdfs:label>
        <skos:notation>UBERON:0000178</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000465 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000465">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001062"/>
        <obo:IAO_0000115>Anatomical entity that has mass.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33090"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
        <oboInOwl:hasDbXref>AAO:0010264</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>AEO:0000006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BILA:0000006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CARO:0000006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0003006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:00007016</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:67165</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HAO:0000006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0001836</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TGMA:0001826</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0001721</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0000465</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#common_anatomy"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#upper_level"/>
        <rdfs:label>material anatomical entity</rdfs:label>
        <skos:notation>UBERON:0000465</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000945 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000945">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004921"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0013765"/>
        <obo:IAO_0000115>An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002161 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7864"/>
        <obo:RO_0002161 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7878"/>
        <obo:RO_0002161 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7955"/>
        <obo:RO_0002161 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9259"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:UBPROP_0000001>Portion of alimentary canal with increased circular and longitudinal smooth muscle. Bounded posteriorly by the pyloric sphincter. Mucosal lining has increased folding.[AAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000003>It appears that the stomach has an ancient origin. The stomach first appears in the fish lineage. The prevertebrate chordates do not have a true stomach, whereas the cartilaginous and bony fish do. Although most fish do have a true stomach, some fish species appear to have lost the stomach secondarily. The remaining vertebrate lineages do have a true stomach (at least in the adult animal), although there is great variation in the size and shape of the stomach.[well established][VHOG]</obo:UBPROP_0000003>
        <obo:UBPROP_0000008>We restrict this to the vertebrate specific structure - see the grouping class &apos;food storage organ&apos; for analogous structures in other species. Teleosts: Zebrafish is functionally stomach-less, but may retain ontogenic footprint. Although the precise shape and size of the stomach varies widely among different vertebrates, the relative positions of the oesophageal and duodenal openings remain relatively constant. As a result, the organ always curves somewhat to the left before curving back to meet the pyloric sphincter. However, lampreys, hagfishes, chimaeras, lungfishes, and some teleost fish have no stomach at all, with the oesophagus opening directly into the intestine. The gastric lining is usually divided into two regions, an anterior portion lined by fundic glands, and a posterior with pyloric glands. Cardiac glands are unique to mammals, and even then are absent in a number of species. The distributions of these glands vary between species, and do not always correspond with the same regions as in man. Furthermore, in many non-human mammals, a portion of the stomach anterior to the cardiac glands is lined with epithelium essentially identical to that of the oesophagus. Ruminants, in particular, have a complex stomach, the first three chambers of which are all lined with oesophageal mucosa</obo:UBPROP_0000008>
        <oboInOwl:hasDbXref>AAO:0000579</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ANISEED:1235297</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0001307</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0980</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000837</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0001915</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:2993</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:17021</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100070</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:7148</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:293</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000353</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000051</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D013270</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000051</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12391</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:181246003</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0002121</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0038351</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000408</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Stomach</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000128</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Stomach</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>stomach chamber</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>anterior intestine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gaster</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>mesenteron</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>ventriculus</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0000945</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#major_organ"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#organ_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>stomach</rdfs:label>
        <skos:notation>UBERON:0000945</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://upload.wikimedia.org/wikipedia/commons/e/e0/Stomach_diagram.svg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001044">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010047"/>
        <obo:IAO_0000115>Saliva-secreting exocrine glands of the oral cavity[GO].</obo:IAO_0000115>
        <obo:IAO_0000232>currently we define saliva and salivary glands very generally in functional terms but it may be more appropriate to split this class. From WP: In most vertebrates, saliva does not contain any enzymes, consisting of mucus and water only, and its primary function is to moisten food while eating. As a result, true salivary glands are rarely found in fish or aquatic tetrapods, although there are often individual mucus-secreting cells. Amphibians have a single salivary gland, the intermaxillary gland, located in the forward part of the palate. Reptiles and birds normally have only very small glands on the lips, palate, and base of the mouth, although there are some birds with large glands, which produce a sticky saliva that helps in nest-building. The distinct parotid, submandibular, and sublingual glands are only developed in mammals.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000001>A gland that produces the saliva. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-25, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]</obo:UBPROP_0000001>
        <obo:UBPROP_0000003>In air-feeding animals, the lack of water column to lubricate the food has been compensated for by the evolution of the salivary glands. These glands are present only in amniotes and are controlled by the parasympathetic system.[well established][VHOG]</obo:UBPROP_0000003>
        <obo:UBPROP_0000008>The salivary glands in mammals are exocrine glands, glands with ducts, that produce saliva. They also secrete amylase, an enzyme that breaks down starch into maltose. In other organisms such as insects, salivary glands are often used to produce biologically important proteins like silk or glues, and fly salivary glands contain polytene chromosomes that have been useful in genetic research. The salivary glands of some species are modified to produce enzymes; salivary amylase is found in many, but by no means all, bird and mammal species (including humans, as noted above). Furthermore, the venom glands of poisonous snakes, Gila monsters, and some shrews, are modified salivary glands</obo:UBPROP_0000008>
        <oboInOwl:hasDbXref>BTO:0001203</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0892</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000859</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0001775</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:7987</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:17751</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100059</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:00005382</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:9597</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:937</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000346</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000079</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012469</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000079</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12426</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:181236000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0036098</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000376</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Salivary_gland</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:SalivaryGland</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>salivary gland</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>glandulae salivariae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0001044</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#functional_classification"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#organ_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <rdfs:label>saliva-secreting gland</rdfs:label>
        <skos:notation>UBERON:0001044</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/5/51/Illu_quiz_hn_02.jpg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001045">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004921"/>
        <obo:IAO_0000115>Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO].</obo:IAO_0000115>
        <obo:IAO_0000116>Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. We may explicitly make this a developmental class</obo:IAO_0000116>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000003>The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]</obo:UBPROP_0000003>
        <obo:UBPROP_0000008>In humans: originates from the foregut at the opening of the bile duct into the duodenum and continues through the small intestine and much of the large intestine until the transition to the hindgut about two-thirds of the way through the transverse colon</obo:UBPROP_0000008>
        <obo:UBPROP_0000012>in FMA this represents an embryonic region.</obo:UBPROP_0000012>
        <oboInOwl:hasDbXref>BILA:0000086</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0000863</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0001950</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0001185</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:983</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:16255</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:00005383</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:45617</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0001564</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C34210</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:361410004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TGMA:0001036</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0231052</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000290</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Midgut</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000103</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>mesenteron</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0001045</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#developmental_classification"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <rdfs:label>midgut</rdfs:label>
        <skos:notation>UBERON:0001045</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/3/3d/Illu_small_intestine.jpg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001046">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004921"/>
        <obo:IAO_0000115>The caudalmost subdivision of a digestive tract.</obo:IAO_0000115>
        <obo:IAO_0000116>Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future (vertebrates have some contribution from NC - https://github.com/obophenotype/uberon/wiki/The-neural-crest). We may explicitly make this a developmental class</obo:IAO_0000116>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000001>the caudal portion of the primitive digestive tube of the embryo</obo:UBPROP_0000001>
        <obo:UBPROP_0000003>The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]</obo:UBPROP_0000003>
        <obo:UBPROP_0000012>in FMA this class has no children. In MA it has a single child hindgut epithelium</obo:UBPROP_0000012>
        <oboInOwl:hasDbXref>AAO:0011052</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BILA:0000087</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0000510</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0000779</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:975</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:16715</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:00005384</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:45618</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0001527</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C34188</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:362856002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TGMA:0001020</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0231053</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000459</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Hindgut</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000104</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>metenteron</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0001046</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#developmental_classification"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <rdfs:label>hindgut</rdfs:label>
        <skos:notation>UBERON:0001046</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001062">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
        <obo:IAO_0000115>Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33090"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
        <oboInOwl:hasDbXref>AAO:0010841</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>AEO:0000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BFO:0000004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BILA:0000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BIRNLEX:6</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CARO:0000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0002229</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:10000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:62955</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HAO:0000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12219</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0100000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TGMA:0001822</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C1515976</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>WBbt:0000100</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0100000</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0001062</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#common_anatomy"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#upper_level"/>
        <rdfs:label>anatomical entity</rdfs:label>
        <skos:notation>UBERON:0001062</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001134 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001134">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002385"/>
        <obo:IAO_0000115>Muscle tissue that consists primarily of skeletal muscle fibers.</obo:IAO_0000115>
        <obo:IAO_0000116>TODO - add skeletal muscle organ? See GO:0060538 skeletal muscle organ development. Todo - group FBbt:00005073 - somatic muscle.</obo:IAO_0000116>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000001>Muscle, composed of long cylindrical, multinucleated cells that attaches to the skeleton via tendons.[TAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000001>Tissue which consists of skeletal muscle fibers surrounded by endomysium. Examples: Skeletal muscle tissue of biceps, Skeletal muscle tissue of diaphragm[FMA]</obo:UBPROP_0000001>
        <obo:UBPROP_0000003>This result implies the following views in terms of evolutionary differentiation: (1) Arthropod striated muscle and vertebrate skeletal and cardiac muscles share a common ancestor. In other words, they did not evolve independently (...) (5) The divergence of vertebrate skeletal and cardiac muscles/vertebrate smooth muscle and nonmuscle is at least before that of vertebrates/arthropods. In other words, emergence of skeletal and cardiac musle type tissues preceded the vertebrate/arthropod divergence (ca. 700 MYA).[well established][VHOG]</obo:UBPROP_0000003>
        <dc:contributor rdf:resource="https://github.com/RDruzinsky"/>
        <dc:contributor rdf:resource="https://github.com/cmungall"/>
        <dc:contributor rdf:resource="https://github.com/dosumis"/>
        <dc:contributor rdf:resource="https://github.com/mellybelly"/>
        <oboInOwl:hasBroadSynonym>skeletal muscle</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>EMAPA:32716</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:14069</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0002439</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C13050</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:426215008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0242692</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Skeletal_striated_muscle</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>skeletal muscle system</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>somatic muscle</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0001134</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>skeletal muscle tissue</rdfs:label>
        <skos:notation>UBERON:0001134</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://upload.wikimedia.org/wikipedia/commons/c/c0/Skeletal_muscle.jpg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004120"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0018707"/>
        <obo:IAO_0000115>Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP].</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002161 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:UBPROP_0000001>A saccular organ in which urine accumulates before discharge from the body. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]</obo:UBPROP_0000001>
        <obo:UBPROP_0000001>Anatomical structure which consists of a membranous sac used to temporarily store urine until it is excreted from the body.[AAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000003>In tetrapods, the urinary bladder arises as an outpocketing of the cloaca. (...) The tetrapod urinary bladder appears first among amphibians and is present in Sphenodon, turtles, most lizards, ostriches among birds, and all mammals.[well established][VHOG]</obo:UBPROP_0000003>
        <obo:UBPROP_0000007>vesical</obo:UBPROP_0000007>
        <obo:UBPROP_0000008>The urinary bladder evolved in tetrapods. Birds to not possess a true urinary bladder, although Palaeognathae have an undifferentiated cloacal outpocketing that serves a similar function[https://github.com/obophenotype/uberon/issues/454]</obo:UBPROP_0000008>
        <oboInOwl:hasBroadSynonym>bladder</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>AAO:0000623</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0001418</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-1090</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000290</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0000174</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:9328</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:18321</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100098</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:15900</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:0000004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000380</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000122</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001743</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000122</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12414</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:302512001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0005682</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000740</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Urinary_bladder</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000154</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:UrinaryBladder</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>vesica urinaria</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>urocyst</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>vesica</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0001255</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#major_organ"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#organ_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <rdfs:label>urinary bladder</rdfs:label>
        <skos:notation>UBERON:0001255</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://cdn.humanatlas.io/digital-objects/ref-organ/urinary-bladder-female/v1.2/assets/3d-vh-f-urinary-bladder.glb</foaf:depiction>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://cdn.humanatlas.io/digital-objects/ref-organ/urinary-bladder-male/v1.2/assets/3d-vh-m-urinary-bladder.glb</foaf:depiction>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001359">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0006314"/>
        <obo:IAO_0000115>A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord.</obo:IAO_0000115>
        <obo:IAO_0000116>many sources state the CP as sole producer of CSF, but this is disputed [DOI:10.1007/s11064-015-1581-6]</obo:IAO_0000116>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000001>Portion of organism substance that is a clear fluid that occupies the subarachnoid space and the ventricular system around and inside the brain.[TAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000003>In vertebrates, at early stages of Central Nervous System (CNS) development, the architecture of the brain primordium reveals the presence of the cavity of brain vesicles, which is filled by Embryonic Cerebro-Spinal Fluid (E-CSF). (...) Rat and chick E-CSF proteomes are similar, although rat is more complex in certain groups of proteins, e.g., apolipoproteins, which may be involved in the control of neural diversity, and has soluble enzymes present, just like adult human CSF, but unlike chick E-CSF, revealing phylogenetic brain differences between these groups of vertebrates.[uncertain][VHOG]</obo:UBPROP_0000003>
        <obo:UBPROP_0000012>EHDAA2 models this as developing from CP, which is wrong</obo:UBPROP_0000012>
        <obo:UBPROP_0000012>the FMA def states that this is subarachnoid spaces only. ZFA def states subarachnoid spaces and brain ventricles, but not SC (and has part_of to brain). Circulation: It circulates from the lateral ventricles to the foramen of Monro (Interventricular foramen), third ventricle, aqueduct of Sylvius (Cerebral aqueduct), fourth ventricle, foramen of Magendie (Median aperture) and foramina of Luschka (Lateral apertures), subarachnoid space over brain and spinal cord. It should be noted that the CSF moves in a pulsatile manner throughout the CSF system with nearly zero net flow. CSF is reabsorbed into venous sinus blood via arachnoid granulations.</obo:UBPROP_0000012>
        <oboInOwl:hasDbXref>BIRNLEX:1798</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0000237</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0130</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000329</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0004441</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ENVO:02000029</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100311</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:20935</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:1181</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0002503</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000499</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D002555</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12692</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0002184</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0007806</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0001278</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Cerebrospinal_fluid</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0001626</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>CSF</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>cerebral spinal fluid</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>liquor cerebrospinalis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>spinal fluid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0001359</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>cerebrospinal fluid</rdfs:label>
        <skos:notation>UBERON:0001359</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001638 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001638">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001981"/>
        <obo:IAO_0000115>Any of the tubular branching vessels that carry blood from the capillaries toward the heart.</obo:IAO_0000115>
        <obo:IAO_0000116>TODO - check with MA - vein vs venous blood vessel</obo:IAO_0000116>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000001>Part of the circulatory system composed of blood vessels which carry blood from other organs, tissues, and cells to the heart.[AAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000003>The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]</obo:UBPROP_0000003>
        <obo:UBPROP_0000007>venous</obo:UBPROP_0000007>
        <obo:UBPROP_0000202 rdf:resource="http://purl.obolibrary.org/obo/FMA_63814"/>
        <oboInOwl:hasBroadSynonym>venous subtree</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>venous vessel</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>AAO:0010212</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>AEO:0000209</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0000234</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-1108</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000816</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0003254</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:35906</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100031</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:50723</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:492</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000067</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000037</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D014680</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000037</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12814</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:181367001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0000082</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0042449</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0001743</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Vein</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000115</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0000082</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Vein</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>venous tree organ part</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>vascular element</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>vena</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>venae</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0001638</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>vein</rdfs:label>
        <skos:notation>UBERON:0001638</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/c/c2/Venous_system_en.svg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001981 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001981">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004120"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010000"/>
        <obo:IAO_0000115>A vessel through which blood circulates in the body.</obo:IAO_0000115>
        <obo:IAO_0000116>consider adopting the EMAPA superclass &apos;vascular element&apos;, which includes microvasculature (e.g. capillaries), vascular plexus</obo:IAO_0000116>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:UBPROP_0000001>Any of the vessels through which blood circulates in the body. [XAO:0001011_][VHOG]</obo:UBPROP_0000001>
        <obo:UBPROP_0000001>Any of the vessels through which blood circulates in the body.[AAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000003>The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]</obo:UBPROP_0000003>
        <obo:UBPROP_0000008>annelids have blood vessels, but this class is not applicable to annelids.</obo:UBPROP_0000008>
        <obo:UBPROP_0000012>FMA:63183 Blood vessel is categorized as &apos;general anatomical term&apos;. Suggestion to map to region of vascular tree from Terry H at JAX</obo:UBPROP_0000012>
        <oboInOwl:hasBroadSynonym>vascular element</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>AAO:0011004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>AEO:0000207</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0001102</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0080</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000817</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0003252</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:240</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:32743</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:35993</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:50722</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:63183</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:169</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000060</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000393</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001808</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12679</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NLXANAT:090901</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:361097006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0002137</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0005847</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0001250</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Blood_vessel</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0001011</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0005314</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>region of vascular tree organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>vascular tree organ region</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>vas sanguineum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0001981</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>blood vessel</rdfs:label>
        <skos:notation>UBERON:0001981</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002072 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002072">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000064"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004120"/>
        <obo:IAO_0000115>Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP].</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:UBPROP_0000001>A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000001>A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA:70544].</obo:UBPROP_0000001>
        <obo:UBPROP_0000007>hypodermal</obo:UBPROP_0000007>
        <obo:UBPROP_0000007>subcutaneous</obo:UBPROP_0000007>
        <obo:UBPROP_0000007>subcutaneus</obo:UBPROP_0000007>
        <obo:UBPROP_0000012>BTO has &apos;subcutis&apos;, as part of dermis. We follow FMA in having distinct classes for hypodermis and superficial fascia, and including these as part of the non-skin intgeument.</obo:UBPROP_0000012>
        <oboInOwl:hasDbXref>BTO:0001314</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-2366</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:37505</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:70544</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D040521</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C33645</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0001136</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0278403</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Hypodermis</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0001136</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>hypoderm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>vertebrate hypodermis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>sub-tegumental tissue</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>subcutaneous tissue</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>subcutis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>subtegumental tissue</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>superficial fascia</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>tela subcutanea</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0002072</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>hypodermis</rdfs:label>
        <skos:notation>UBERON:0002072</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002097">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000062"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004121"/>
        <obo:IAO_0000115>The organ covering the body that consists of the dermis and epidermis.</obo:IAO_0000115>
        <obo:IAO_0000232>consider &apos;integumentary system&apos; for invertebrates</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:UBPROP_0000012>MA uses the term skin to refer to what is called here: zone of skin</obo:UBPROP_0000012>
        <oboInOwl:hasDbXref>BTO:0001253</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0934</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000962</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0001844</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:17525</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:7163</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012867</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MFMO:0000099</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12470</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:181469002</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C1123023</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Skin</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000023</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Skin</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>entire skin</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>skin organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>entire integument</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>integument</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>integumental organ</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>pelt</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>skin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0002097</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#major_organ"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <rdfs:label>skin of body</rdfs:label>
        <skos:notation>UBERON:0002097</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg</foaf:depiction>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://cdn.humanatlas.io/digital-objects/ref-organ/skin-female/v1.4/assets/3d-vh-f-skin.glb</foaf:depiction>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://cdn.humanatlas.io/digital-objects/ref-organ/skin-male/v1.3/assets/3d-vh-m-skin.glb</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002358 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002358">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000042"/>
        <obo:IAO_0000115>A serous membrane that lines the peritoneal cavity[VHOG,modified].</obo:IAO_0000115>
        <obo:IAO_0000116>TODO - in ZFA is_a epithelium</obo:IAO_0000116>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000001>An epithelium that lines the peritoneal cavity.[TAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000001>Serous membrane that forms the lining of the abdominal cavity or the coelom. It covers most of the intra-abdominal organs, supports the abdominal organs, and serves as a conduit for their blood and lymph vessels and nerves. It is composed of a layer of mesothelium.[AAO]</obo:UBPROP_0000001>
        <obo:UBPROP_0000007>peritoneal</obo:UBPROP_0000007>
        <obo:UBPROP_0000012>todo: check MA/EMAPA.</obo:UBPROP_0000012>
        <oboInOwl:hasDbXref>AAO:0010814</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0001472</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-2072</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100087</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:9584</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:18</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0000449</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D010537</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12770</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0005120</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0031153</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0001257</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Peritoneum</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000139</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0005120</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Peritoneum</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>peritonaeum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0002358</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core"/>
        <rdfs:label>peritoneum</rdfs:label>
        <skos:notation>UBERON:0002358</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002385">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004120"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010000"/>
        <obo:IAO_0000115>Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO].</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002171 rdf:resource="http://purl.obolibrary.org/obo/UBERON_0003714"/>
        <obo:UBPROP_0000001>One of the four types of tissue in traditional classifications. Tissue that contains cells with contractile filaments that move past each other and change the size of the cell. Muscle tissue also is separated into three distinct categories.[AAO]</obo:UBPROP_0000001>
        <oboInOwl:hasDbXref>AAO:0000306</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>AEO:0000122</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0642</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0003122</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:32715</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:9641</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0002437</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009132</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C12435</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:91727004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C2328219</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Muscle_tissue</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:MuscleTissue</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>muscular tissue</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>portion of muscle tissue</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>textus muscularis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0002385</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <rdfs:comment>Vertebrate muscle is categorized into three major muscle types defined by their structural and functional properties: skeletal, cardiac and smooth. In Dmel the counterparts are somatic, heart/cardiac and visceral. Here we take a cell type based approach.</rdfs:comment>
        <rdfs:label>muscle tissue</rdfs:label>
        <skos:notation>UBERON:0002385</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002530 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002530">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000062"/>
        <obo:IAO_0000115>An organ that functions as a secretory or excretory organ.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002171 rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001434"/>
        <obo:UBPROP_0000007>glandular</obo:UBPROP_0000007>
        <oboInOwl:hasDbXref>AAO:0000212</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>AEO:0000096</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0000522</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000797</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0003096</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:2161</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:18425</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:00100317</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:7146</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:86294</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HAO:0000375</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0003038</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000021</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000021</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C13319</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:134358001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C1285092</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Gland</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>WikipediaCategory:Glands</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Gland</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>glandular organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Druese</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>glandula</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0002530</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim"/>
        <rdfs:label>gland</rdfs:label>
        <skos:notation>UBERON:0002530</skos:notation>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://upload.wikimedia.org/wikipedia/commons/a/a1/Gray1026.png</foaf:depiction>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0003408 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0003408">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002530"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0013765"/>
        <obo:IAO_0000115>A gland that is part of a digestive tract [Automatically generated definition].</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <oboInOwl:hasDbXref>EMAPA:18815</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MA:0003202</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>digestive tract gland</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>gland of digestive tract</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>gland of lower gastrointestinal tract</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>gut gland</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>lower gastrointestinal tract gland</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0003408</oboInOwl:id>
        <rdfs:label>gland of digestive tract</rdfs:label>
        <skos:notation>UBERON:0003408</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000061"/>
        <obo:IAO_0000115>An anatomical structure that develops (entirely or partially) from the mesoderm.</obo:IAO_0000115>
        <obo:IAO_0000232>Grouping term for query purposes</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <oboInOwl:hasExactSynonym>mesodermal derivative</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0004120</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#grouping_class"/>
        <rdfs:label>mesoderm-derived structure</rdfs:label>
        <skos:notation>UBERON:0004120</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004121">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000061"/>
        <obo:IAO_0000115>An anatomical structure that develops (entirely or partially) from the ectoderm.</obo:IAO_0000115>
        <obo:IAO_0000232>Grouping term for query purposes</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <oboInOwl:hasExactSynonym>ectodermal deriviative</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0004121</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#grouping_class"/>
        <rdfs:label>ectoderm-derived structure</rdfs:label>
        <skos:notation>UBERON:0004121</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004921 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004921">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000064"/>
        <obo:IAO_0000115>A proximal-distal subdivision of the digestive tract.</obo:IAO_0000115>
        <obo:IAO_0000232>intended to denote both embryonic and adult structures. Note the FMA grouping here is not quite correct.</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:hasDbXref>FBbt:00100315</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:71131</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>alimentary system subdivision</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gut section</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>intestinal tract</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>segment of intestinal tract</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>subdivision of alimentary system</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0004921</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#human_reference_atlas"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#non_informative"/>
        <rdfs:label>subdivision of digestive tract</rdfs:label>
        <skos:notation>UBERON:0004921</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0006314 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0006314">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000465"/>
        <obo:IAO_0000115>Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <oboInOwl:hasBroadSynonym>fluid</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>BIRNLEX:20</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:37441</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:280556</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:266</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D001826</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Body_fluid</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:BodyFluid</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>body fluid</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0006314</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <rdfs:label>bodily fluid</rdfs:label>
        <skos:notation>UBERON:0006314</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0010000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000061"/>
        <obo:IAO_0000115>An anatomical structure that has more than one cell as a part.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33090"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33208"/>
        <obo:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
        <oboInOwl:hasDbXref>CARO:0010000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FBbt:00100313</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>multicellular structure</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0010000</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#common_anatomy"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#upper_level"/>
        <rdfs:label>multicellular anatomical structure</rdfs:label>
        <skos:notation>UBERON:0010000</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0010047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0003408"/>
        <obo:IAO_0000115>Gland of the epithelium lining the oral cavity. The most common are the salivary glands.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <obo:UBPROP_0000012>Note that Kardong classifies lacrimal glands here. EHDAA2 includes pituitary primordium, as this develops from oral mucosa</obo:UBPROP_0000012>
        <oboInOwl:hasAlternativeId>UBERON:0003293</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>EHDAA2:0001327</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA:2181</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:16572</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:16723</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>VHOG:0000652</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>buccal gland</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>gland of oral opening</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>gland of oral region</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>mouth gland</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>oral cavity gland</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>oral region gland</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>UBERON:0010047</oboInOwl:id>
        <rdfs:label>oral gland</rdfs:label>
        <skos:notation>UBERON:0010047</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0013765 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0013765">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000062"/>
        <obo:IAO_0000115>Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <oboInOwl:hasDbXref>EMAPA:37843</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:272627002</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>digestive organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>digestive system organ</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0013765</oboInOwl:id>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#grouping_class"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim"/>
        <rdfs:label>digestive system element</rdfs:label>
        <skos:notation>UBERON:0013765</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0018707 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0018707">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000062"/>
        <obo:IAO_0000115>A membranous sac in animals that serves as the receptacle of a liquid or contains gas.</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
        <oboInOwl:hasDbXref>BTO:0000123</oboInOwl:hasDbXref>
        <oboInOwl:hasNarrowSynonym>bladder</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:id>UBERON:0018707</oboInOwl:id>
        <rdfs:label>bladder organ</rdfs:label>
        <skos:notation>UBERON:0018707</skos:notation>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000000">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000420"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000000</metadata:prefixIRI>
        <metadata:treeView rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <obo1:part_of rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <obo:IAO_0000115>A pathogen component in vaccine that contains only a part of the pathogen organism instead of the whole organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>part of pathogen organism in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000001">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000047"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000278"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000295"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000278"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000494"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000001</metadata:prefixIRI>
        <obo:IAO_0000115>Material entity that is manufactured to realize the vaccine function.</obo:IAO_0000115>
        <obo:IAO_0000116>Many vaccines are developed to protect against infectious pathogens that causes infectious diseases. Many vaccines are also being developed against other diseases such as cancer, allergy, and autoimmune diseases.</obo:IAO_0000116>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:OBI_0000295 rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <oboInOwl:hasDbXref>MeSH: D014612</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000002">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0600007"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0600007"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000319"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000444"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000081"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001274"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000002</metadata:prefixIRI>
        <obo:IAO_0000115>Process of administering a vaccine in vivo to a recipient (e.g., a human), with the intent to invoke a protective or therapeutic adaptive immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine administration</obo:IAO_0000118>
        <obo:RO_0000057 rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000003">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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        <obo:IAO_0000116>Preparation: The vaccine consists of the Haemophilus b capsular polysaccharide (polyribosyl-ribitol-phosphate, PRP), a high molecular weight polymer prepared from the Haemophilus influenzae  type b (HiB) strain 1482 grown in a semi-synthetic medium, covalently bound to tetanus toxoid. The tetanus toxoid is prepared by extraction, ammonium sulfate purification, and formalin inactivation of the toxin from cultures of Clostridium tetani (Harvard strain) grown in a modified Mueller and Miller medium. The toxoid is filter sterilized prior to the conjugation process. When ActHIB vaccine is reconstituted with saline diluent, each single dose of 0.5 mL is formulated to contain 10 mu g of purified capsular polysaccharide conjugated to 24 mu g of inactivated tetanus toxoid, and 8.5% of sucrose (ActHIB 2005). 
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    <!-- http://purl.obolibrary.org/obo/VO_0000006 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094043.htm</obo:IAO_0000119>
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        <obo:VO_0001818>325</obo:VO_0001818>
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        <obo:VO_0003160>For active immunization of persons ages 6 months of age and older against influenza disease caused by influenza virus subtypes A and type B present in the vaccine.</obo:VO_0003160>
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        <obo:VO_0003162>BL 125254</obo:VO_0003162>
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        <rdfs:label>Afluria vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000007 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:comment>Product Name: Measles Virus Vaccine, Live</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/VO_0000008 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>vaccine-induced lymphocyte activation</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000009 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>vaccine-induced B cell antigen processing and presentation</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000010 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>vaccine-induced B cell cytokine production</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000011 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>vaccine B cell epitope</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000012 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>vaccine-induced B cell mediated immunity</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000013 -->

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        <obo:IAO_0000115>A vaccine that protects against Bacillus anthrax that causes anthrax.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0000014 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000021</metadata:prefixIRI>
        <obo:IAO_0000115>Brucella abortus vaccine RB51 is a Brucella abortus vaccine that is licensed in the USA since 1992.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus RB51</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella RB-51</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella RB51</obo:IAO_0000118>
        <obo:IAO_0000118>SRB51</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10534009</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11193615</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11500423</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11504226</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11504238</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11553603</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11768128</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12119140</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12438380</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12704101</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:1439207</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16713034</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:17653832</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:17894637</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:18836016</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:1908158</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:19362381</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:19439382</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7622248</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7806364</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7927779</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:8039890</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:8740701</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:8890203</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=10</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://rb51.com</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/VO_0000794"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>10</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9901"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus vaccine RB51</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000022 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000022</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated Brucella abortus vaccine that is licensed and used in many countries.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Brucella S19</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella strain-19</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11058778</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:8039890</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=109</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>109</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus vaccine strain 19</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000024">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000024</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pVAX1 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000025 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000025">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003550"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000025</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Brucella that causes brucellosis in animals and humans.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>brucellosis vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
        <oboInOwl:hasDbXref>MeSH: D002004</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
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            <owl:Restriction>
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                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000026</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:hasAlternativeId>VO:0000217</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV4 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
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                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000027</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pAp031 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000028 -->

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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000746"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010437"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010439"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000028</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3180</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=368</obo:IAO_0000119>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/139056</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003150"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003408"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3180</obo:VO_0001818>
        <obo:VO_0001818>368</obo:VO_0001818>
        <obo:VO_0003099>Comvax</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Product Name: Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate) &amp; Hepatitis B Vaccine (Recombinant)</rdfs:comment>
        <rdfs:label>Comvax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000029 -->

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        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000641"/>
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        <rdfs:subClassOf>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MenHibrix vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000032">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000032</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is composed of a plasmid vaccine vector (a circular double stranded DNA molecule) containing the whole of parts of genes encoding one or more vaccine antigen proteins.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>genetic vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>naked DNA vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>nucleic acid vaccine</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000732"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010436"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010445"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000700"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000033</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Diphtheria and Tetanus Toxoids Adsorbed USP by Sanofi Pasteur Inc</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=313</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=353</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=362</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>313</obo:VO_0001818>
        <obo:VO_0001818>353</obo:VO_0001818>
        <obo:VO_0001818>362</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Product Name: Diphtheria &amp; Tetanus Toxoids Adsorbed</rdfs:comment>
        <rdfs:label>Diphtheria and Tetanus Toxoids Adsorbed USP vaccine by Sanofi Pasteur Inc</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000034">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000034</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000033"/>
        <rdfs:comment>Product Name: Diphtheria &amp; Tetanus Toxoids Adsorbed</rdfs:comment>
        <rdfs:comment>This term is obsolete since there is another term with the same meaning.</rdfs:comment>
        <rdfs:label>obsolete Diphtheria and Tetanus Toxoids Adsorbed by Sanofi Pasteur Ltd</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000035">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000433"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018956"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000433"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010452"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000701"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018956"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000035</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccinia virus vaccine that is a freeze-dried calf lymph smallpox vaccine, specifically, Dryvax is a live-virus preparation of vaccinia prepared from calf lymph. </obo:IAO_0000115>
        <obo:IAO_0000116>Dryvax is a freeze-dried calf lymph smallpox vaccine. It is the world&apos;s oldest smallpox vaccine, created in the late 19th century by American Home Products, a predecessor of Wyeth. By the 1940s, Wyeth was the leading US manufacturer of the vaccine and the only manufacturer by the 1960s. After world health authorities declared smallpox had been eradicated from nature in 1980, Wyeth stopped making the vaccine.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://en.wikipedia.org/wiki/Dryvax</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>Dryvax</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Product Name: Smallpox Vaccine, Dried, Calf Lymph Type</rdfs:comment>
        <rdfs:label>Dryvax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000619"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000036</metadata:prefixIRI>
        <obo:IAO_0000115>A CFA/I‐expressing vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17566016</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=116</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>116</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ETEC vaccine ACAM2010</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000037 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000037">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10508"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1579"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10508"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000037</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection of an adenovirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1579"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10508"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>adenovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000038">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000038</metadata:prefixIRI>
        <obo:IAO_0000115>An assay that measures the persistent survival of live vaccine in a host in vivo.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>vaccine persistence assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000039 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000039">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000039</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pBacPAK9 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000040</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pBC12/CMV DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000041">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003552"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000041</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that prevents against Escherichia coli infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. coli vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:hasDbXref>MeSH: D022361</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Escherichia coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000042">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000042</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pBHT DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000043">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000047 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.htm</obo:IAO_0000119>
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        <obo:VO_0001818>330</obo:VO_0001818>
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        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM619664.pdf</obo:VO_0003161>
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    <!-- http://purl.obolibrary.org/obo/VO_0000048 -->

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        <obo:IAO_0000115>A gene that once deleted, would make an attenuated microbe that can be used as a live attenuated vaccine against virulent pathogen.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000049 -->

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        <obo:IAO_0000115>Quadrivalent vaccine meaning it protects against 4 strains of virus (types 6, 11, 16, and 18). The vaccine was made using genetic engineering techniques. The genes that encode a specific protein from each of these strains are expressed in yeast in large-scale fermentation cultures. Protein purification methods are then used to isolate the proteins and make the vaccine.
Cited from: 
http://biotech.about.com/b/2008/09/03/gardasil-safety-of-genetically-engineered-hpv-vaccine-still-in-question.htm</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094042.htm</obo:IAO_0000119>
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        <obo:VO_0001818>337</obo:VO_0001818>
        <obo:VO_0003099>Gardasil</obo:VO_0003099>
        <obo:VO_0003160>- Prevention of vulvar and vaginal cancer
- Vaccination in females 9 through 26 years of age for prevention of the following diseases caused by Human Papillomavirus (HPV) Types 6, 11, 16, and 18:
     - Cervical Cancer
     - Genital warts (condyloma acuminata) and the following precancerous or dysplastic lesions:
          - Cervical adenocarcinoma in situ (AIS)cancer
          - Cervical intraepithelial neoplasia (CIN) grade 2 and grade 3
          - Vulvar intraepithelial neoplasia (VIN) grade 2 and grade 3
          - Vaginal intraepithelial neoplasia (VaIN) grade 2 and grade 3
          - Cervical intraepithelial neoplasia (CIN) grade 1
- Vaccination in boys and men 9 through 26 years of age for the prevention of genital warts caused by HPV types 6 and 11
- Vaccination in people ages 9 through 26 years for the prevention of anal cancer and associated precancerous lesions due to human papillomavirus (HPV) types 6, 11, 16, and 18</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM111263.pdf</obo:VO_0003161>
        <obo:VO_0003162>125126</obo:VO_0003162>
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        <rdfs:label>Gardasil vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000050 -->

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        <obo:IAO_0000115>a lentivirus vaccine vector that uses a HIV strain as the vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000051 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>Balb/c mouse</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000052 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000053 -->

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        <obo:IAO_0000115>IPOL, Poliovirus Vaccine Inactivated is a sterile suspension of three types of poliovirus: Type 1 (Mahoney), Type 2 (MEF-1), and Type 3 (Saukett). IPOL vaccine is a highly purified, inactivated poliovirus vaccine with enhanced potency.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0000055 -->

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        <obo:IAO_0000115>a bacterial vaccine vector that uses L. moncytogenes as the vector.</obo:IAO_0000115>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000073</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>Meruvax II</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11041"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Product Name: Rubella Virus Vaccine Live</rdfs:comment>
        <rdfs:label>Meruvax II vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000074 -->

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        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000656"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010442"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000074</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>Mumpsvax</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Product Name: Mumps Virus Vaccine Live</rdfs:comment>
        <rdfs:label>Mumpsvax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000075">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000075</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pBI/tTA DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000076</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pBISIA DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000077 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000077</metadata:prefixIRI>
        <obo:IAO_0000115>A Mycobacterium vaccine that protects against Mycobacterium tuberculosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>tuberculosis vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000078 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000078">
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000078</metadata:prefixIRI>
        <obo:IAO_0000115>Mycobax is a BCG vaccine that is made by Sanofi Pasteur, Ltd.
Ref: http://www.biopharma.com/cgi/full6.lasso?Key=412.65916</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Mycobax</obo:IAO_0000118>
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        <obo:VO_0001818>315</obo:VO_0001818>
        <obo:VO_0003099>Mycobax</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Product Name: BCG Vaccine</rdfs:comment>
        <rdfs:label>Mycobax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000079 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000079">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000079</metadata:prefixIRI>
        <obo:IAO_0000115>an influenza vaccine that is similar to Fluzone but has high dose. </obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=754</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM305079.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010394"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>754</obo:VO_0001818>
        <obo:VO_0003160>Fluzone High-Dose is indicated for active immunization of persons 65 years of age and older against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM619541.pdf</obo:VO_0003161>
        <obo:VO_0003162>BL 103914</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Product Name: Influenza Virus Vaccine, Trivalent, Types A and B</rdfs:comment>
        <rdfs:label>Fluzone High-dose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000080</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pBK-SFV DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000081 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000081">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
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    <!-- http://purl.obolibrary.org/obo/VO_0000095 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000096 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000097 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000098 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000099 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0000100 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000101 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>vaccine-induced T-helper 2 type immune response</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000102 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM152826.pdf</obo:VO_0003161>
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    <!-- http://purl.obolibrary.org/obo/VO_0000103 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000104 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000105 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000106 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000107 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000110 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000112 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000113 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000114 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000115 -->

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        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0000116 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000117 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000118 -->

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        <obo:IAO_0000115>A vaccine adjuvant that contains microbial derived material.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0000119 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000120 -->

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        <rdfs:label>Vivotif (USA)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000121 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=346</obo:IAO_0000119>
        <obo:IAO_0000119>http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm180913.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        <obo:VO_0001818>346</obo:VO_0001818>
        <obo:VO_0003099>YF-Vax</obo:VO_0003099>
        <obo:VO_0003160>For active immunization of persons 9 months of age and older who:
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- Travelling internationally to countries that require evidence of vaccination from entering travelers or;
- Laboratory Personnel who might be expose to virulent yellow fever virus or to concentrated preparations of the yellow fever vaccine strain by direct or indirect contact or by aerosols should by vaccinated.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142831.pdf</obo:VO_0003161>
        <obo:VO_0003162>BL 103915</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11089"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>YF-Vax vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000122 -->

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        <obo:IAO_0000115>a viral vaccine vector that uses Yellow fever vaccine strain 17D as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 16755933</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Yellow fever 17D vaccine vector</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000123 -->

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        <obo:IAO_0000115>A viral vaccine that protects against infection with Yellow fever virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>yellow fever vaccine</obo:IAO_0000118>
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        <rdfs:label>yellow fever virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000124 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Zostavax vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000125 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>licensed turkey vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000126 -->

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        <obo:IAO_0000115>a vaccine organism that is live and attenuated</obo:IAO_0000115>
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        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>live attenuated vaccine organism</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000127 -->

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        <obo:IAO_0000115>An aluminum vaccine adjuvant that contains aluminum hydroxide.</obo:IAO_0000115>
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        <obo:IAO_0000118>alum</obo:IAO_0000118>
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        <rdfs:label>aluminum hydroxide vaccine adjuvant</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000128 -->

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        <obo:IAO_0000115>An aluminum vaccine adjuvant that is aluminum phosphate.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0000129 -->

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        <obo:IAO_0000115>Vaccination frequency is a qualitative term that represents how many times vaccination has occurred.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0000130 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000131 -->

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        <obo:IAO_0000115>A mineral salt vaccine adjuvant composed of calcium phosphate.</obo:IAO_0000115>
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        <rdfs:label>calcium phosphate vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000132 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000132">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000132</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcDNA3 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000133 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000133">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000133</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant that consists of a water-in-oil emulsion of aqueous antigen in paraffin (mineral) oil of low specific gravity and low viscosity. It is named after Jules T. Freund (1890-1960), Hungarian-born American immunologist. It is a water in oil emulsion.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Freund&apos;s emulsified oil adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000134 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000134">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000115"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000134</metadata:prefixIRI>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced T cell proliferation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000135 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000135">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000287"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000135</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced adaptive immune response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000136 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000136">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000136</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses an adenovirus as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>adenovirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10508</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000137 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000137">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000137</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine role that indicates the vaccine being a combination vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>combination vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000139 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000139">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000133"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000139</metadata:prefixIRI>
        <obo:IAO_0000115>A Freund&apos;s emulsified oil adjuvant that contains inactivated and dried mycobacteria, usually Mycobacterium tuberculosis (the pathogenic agent of tuberculosis).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>complete Freund&apos;s adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000140 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000140">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000148"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000140</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>agglutinating antibody role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000141 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000141">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000141</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>obsolete virulence factor</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000142 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000142">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000133"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000142</metadata:prefixIRI>
        <obo:IAO_0000115>A Freund&apos;s emulsified oil adjuvant that does not contain the mycobacterial components.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>incomplete Freund&apos;s adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000143 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000143">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000143</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant consisting of cholera toxin (CT) from Vibrio cholerae.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>CT</obo:IAO_0000118>
        <obo:IAO_0000118>cholera toxin</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>cholera toxin vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000144 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000144">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000144</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses an alphavirus as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>alphavirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11019</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000145 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000145">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003439"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000145</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine vector role that inheres in a recombinant vaccine vector as a vaccine component. The combination of a recombinant vaccine vector and a heterogenous protective antigen(s) inserted inside the vector for a recombinant vector vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>recombinant vaccine vector role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000146</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant that is the P40 particulate fraction isolated from Corynebacterium.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:8447157</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Corynebacterium-derived P40 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000147 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000147">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000415"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000147</metadata:prefixIRI>
        <obo:IAO_0000115>an adjuvant role that inheres in a vaccine component which is added as part of a vaccine and induces enhanced adaptive immune response to the vaccine antigen. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:comment>The Latin &quot;adjuvans&quot; means to help, particularly to reach a goal.

Adjuvant therapy for cancer is surgery followed by chemotherapy or radiation to help decrease the risk of the cancer recurring (coming back).

An adjuvant is a substance that helps and enhances the pharmacological effect of a drug or increases the ability of an antigen to stimulate the immune system.</rdfs:comment>
        <rdfs:label>vaccine adjuvant role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000148 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000148">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000148</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>antibody role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000555"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000150</metadata:prefixIRI>
        <obo:IAO_0000115>A titer of antibody that shows how much antibody an organism has produced that recognizes a particular epitope, expressed as the greatest dilution ratio (or its reciprocal) that still gives a positive result. ELISA is a common means of determining antibody titers.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Antibody_titer</obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>antibody titer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000151 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000151">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000151</metadata:prefixIRI>
        <obo:IAO_0000115>an organismal quality that indicates an organism (e.g., human) is immunized against a disease.</obo:IAO_0000115>
        <obo:IAO_0000116>To assign the state of &apos;immunized&apos;, we will need to do some assay to measure indicators of immunity, e.g., antibody titers in serum samples.</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>immunized</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000152 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000152">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000152</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine against an infection with F. tularensis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000153 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000153">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000153</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a toxoid vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>toxoid vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000154 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000154">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000793"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_359391"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000154</metadata:prefixIRI>
        <obo:IAO_0000115>A Brucella abortus gene that has the name sodC and comes from strain 2308. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_359391"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>IMMUNOGENICITY: The SodC protein induces antigen-specific Th1 immune response, as indicated by the specific induction of serum IgG2a, but not IgG1, antibodies and by the secretion of IFN-alpha but not IL-4, by the Cu/Zn SOD-stimulated splenocytes. This gene has been used for vaccine development [PubMed: 10816475][PubMed: 11953393][PubMed: 12933826].    

MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replacement exhibited much greater susceptibility to killing by exogenous O(2)(-) than the parental 2308 strain, supporting a role for SodC in protecting this bacterium from O(2)(-) stress. The B abortus sodC mutant was much more sensitive to killing by cultured resident peritoneal macrophages from C57BL6J mice than 2308, and its attenuation in cultured murine macrophages was enhanced when these phagocytes were treated with gamma interferon. The attenuation of the B abortus sodC mutant in both resting and IFN-gamma-activated macrophages was alleviated in the presence of the NADPH oxidase inhibitor apocynin. Consistently, the B abortus sodC mutant also displayed significant attenuation in infected C57BL6J mice compared to the parental strain. These findings suggest that SodC protects B abortus 2308 from the respiratory burst of host macrophages [PubMed: 15845493].</rdfs:comment>
        <rdfs:label>sodC from B. abortus strain 2308</rdfs:label>
        <rdfs:seeAlso>NCBI Gene GI: 3827840; NCBITaxon: 234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000155 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000155">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000155</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>obsolete bacterial gene</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000156 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000156">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_0000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000156</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>viral gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000157 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000157">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000157</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>HIV gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000158 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000158">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000158</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcDNA3.1 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000159 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000159">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000718"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000159</metadata:prefixIRI>
        <obo:IAO_0000112>Brucella abortus cattle vaccine RB51 was developed by serial passages of virulent B. abortus strain 2308 in vitro in rifampin agar plates (Reference: PMID: 1908158).</obo:IAO_0000112>
        <obo:IAO_0000115>A live attenuated vaccine prepraration process that is performed by serial passages in vitro for pathogen attenuation.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>live attenuated vaccine preparation by serial passages in vitro</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000160 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000160">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003211"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000699"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000160</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=454</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm181971.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>454</obo:VO_0001818>
        <obo:VO_0003160>Active immunization of persons 6 months of age and older against influenza disease caused by pandemic (H1N1) 2009 virus.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM182404.pdf</obo:VO_0003161>
        <obo:VO_0003162>103914</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A (H1N1) 2009 Monovalent Vaccine (Sanofi Pasteur)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000161 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000161">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000161</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. coli gene</obo:IAO_0000118>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Escherichia coli gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000162">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002146"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000162</metadata:prefixIRI>
        <obo:IAO_0000115>a virulence of vaccine organism that shows an avirulent pheontype of the organism as the major component of a vaccine. The avirulence means that an vaccine organism is not virulent and does not cause pathogenic phenotype in a host organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccine organism avirulent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000163 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000163">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000569"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000163</metadata:prefixIRI>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced gene up-regulation controlling intracellular bacterial replication</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000164 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000164">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000164</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000165 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000165">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005504"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000165</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that targets against a bacterial disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
        <oboInOwl:hasDbXref>MeSH: D001428</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bacterial vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000166 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000166">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000599"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000166</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine vector that uses a live bacterium as the vector </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>bacterial vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 2</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000167 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000167">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000167</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcDNA3.1V5HisTOPO/TA DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000168 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000168">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000168</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Salmonella gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000169 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000169">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000169</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Shigella gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000170 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000170">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_0000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000170</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>protozoan gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000171 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000171">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000170"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000171</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Plasmodium gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000172 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000172">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000171"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000172</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000173 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000173">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002146"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000173</metadata:prefixIRI>
        <obo:IAO_0000115>a virulence of vaccine organism that shows an attenuated pheontype of the organism as the major component of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccine organism live attenuated</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000174 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000174">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000170"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000174</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Leishmania gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000175 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000175">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000175</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCEP4 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000176 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000176">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000115"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000176</metadata:prefixIRI>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced T cell differentiation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000177 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000177">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000177</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that prevents or treats cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>neoplasm vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>tumor vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:hasDbXref>MeSH:D019496</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000178">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001103"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000315"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000178</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0001103"/>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a inactivated vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000315"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>inactivated vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000179 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000179">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000179</metadata:prefixIRI>
        <metadata:treeView rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <obo1:part_of rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <obo:IAO_0000115>a processed material that is output of the vaccine preparation and part of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>cardinal part of vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine ingredient</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000180 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000180">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000287"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000180</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced cell activation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000181</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant made from bacterial lipopolysaccharide (LPS) of gram-negative bacteria.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>LPS vaccine adjuvant</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>lipopolysaccharide vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000632"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000182</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced antibacterial agglutination antibody response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000183 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000183">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000183</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000184">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000184</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Ebola virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000185">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000185</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Influenza virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000186 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000186">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000186</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that uses RNA(s) derived from a pathogen organism.</obo:IAO_0000115>
        <obo:IAO_0000116>Using RNA may eliminate the problem of having to tailor a vaccine for each individual patient with their specific immunity. The advantage of RNA is that it can be used for all immunity types and can be taken from a single cell. DNA vaccines need to produce RNA which then prompts the manufacture of proteins. However, RNA vaccine eliminates the step from DNA to RNA.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>mRNA vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/RNA_vaccine</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000187 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000187">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000187</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant formulated to correspond to a component found in a water-soluble extract of cell walls of mycobacteria used in complete Freund&apos;s adjuvant (CFA).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>MDP</obo:IAO_0000118>
        <obo:IAO_0000118>muramyl dipeptide</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:344799</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>muramyl dipeptide vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000188 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000188">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000188</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Dengue virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000189 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000189">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000555"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000189</metadata:prefixIRI>
        <obo:IAO_0000115>A titer measurement of viable bacterial or fungal numbers. Unlike in direct microscopic counts where all cells, dead and living, are counted, CFU measures viable cells. By convenience the results are given as CFU/mL (colony-forming units per milliliter) for water, and CFU/g (colony-forming units per gram) for soil or other porous material.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>CFU</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Colony-forming_unit</obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>colony forming unit</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000190 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000190">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000190</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant that contains an organic polymer with some antigenic epitopes which might be shared with other organic polymers acting as immunostimulators.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>squalene</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>squalene vacccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000191 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000191">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000191</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is an emulsifier called Arlacel A.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>arlacel A</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:2042393</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>arlacel A vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000192">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001271"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000192</metadata:prefixIRI>
        <obo:IAO_0000115>A Montanide vaccine adjuvant that is Montanide 103.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Montanide 103</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Montanide 103 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000193 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000193">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000193</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivitive vaccine adjuvant that contains components from killed Bordetella pertussis. The killed B. pertussis has a strong adjuvant effect on the diphtheria and tetanus toxoids in the DPT vaccines.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis component vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000194">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000812"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000194</metadata:prefixIRI>
        <obo:IAO_0000115>a USA licensed vaccine role that inheres ina vaccine approven to be by the US FDA to be used for humans in the USA. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>FDA licensed vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000195 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000195">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000195</metadata:prefixIRI>
        <obo:IAO_0000115>Conjugate vaccine is vaccine that conjugates/links antigens to the molecules that form the outer coat of disease-causing bacteria to promote an immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A conjugate vaccine is created by covalently attaching a poor (polysaccharide organism) antigen to a carrier protein (preferably from the same microorganism), thereby conferring the immunological attributes of the carrier on the attached antigen. --from wikipedia.</rdfs:comment>
        <rdfs:label>conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000196 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000196">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000196</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a recombinant vector vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>recombinant vector vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000197 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000197">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000197</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001448"/>
        <rdfs:label>obsolete West Nile virus gene</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000198 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000198">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000198</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>chickenpox virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000199 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000199">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000199</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Rubella virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000200 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000200">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000200</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1657331</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/California/7/2009 (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000201 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000201">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001524"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000201</metadata:prefixIRI>
        <obo:IAO_0000116>Characteristics: Inactivated baculovirus expressed PCV2 ORF2 protein; adjuvanted</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Porcilis-PCV2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=387</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>387</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcilis-PCV2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000202 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000202">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000202</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Hepatitis A virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000203 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000203">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001524"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000203</metadata:prefixIRI>
        <obo:IAO_0000116>Characteristics: Inactivated PCD1-2 chimera; adjuvanted</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Suvaxyn PCV2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=388</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>388</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Suvaxyn PCV2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000206 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000206">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001474"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000206</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed pig vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000207 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000207">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OAE_0000055"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000207</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine contraindication is a contraindication that increases the risks of a vaccination. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>contraindication for vaccination</obo:IAO_0000118>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>vaccine contraindication</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000208 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000208">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000208</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine role that is not licensed or in clinical trial; instead, it has been experimently approved to induce protection or treatment effect in vivo in at least an experimental animal model. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine in research role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000209 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000209">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000209</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pHIS64 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000210 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000210">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000584"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000210</metadata:prefixIRI>
        <obo:IAO_0000115>an immune response detection assay that detects specific antiviral antibodies in a test serum. The serum, usually a twofold dilution series, is mixed with a standard number, usually 4 to 8 HA units, of virus and incubated prior to the addition of a standard suspension of erythrocytes. The highest dilution of serum that inhibits hemagglutination is the HI titer of the serum. For example, influenza (AI) viruses agglutinate erythrocytes through the interaction of the virus surface glycoprotein, the hemagglutinin (HA), with receptors on the surface of the erythrocyte. Inhibition of the agglutination reaction by HA subtype-specific antisera is the basis of the hemagglutination-inhibition (HI) assay.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>HI assay</obo:IAO_0000118>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>hemagglutination-inhibition assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000211 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000211">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001139"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000211</metadata:prefixIRI>
        <obo:IAO_0000115>an organismal quality of a whole organism vaccine where the whole organism is inactivated/killed and lacks the capability of replication. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine organism killed</obo:IAO_0000118>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccine organism inactivated</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000212 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000212">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001010"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000212</metadata:prefixIRI>
        <obo:IAO_0000115>a DNA vaccine plasmid that uses the plasmid labeled pCI.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/nuccore/5870896</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCI DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000213 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000213">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000207"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000213</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>hypersensitivity to chicken product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000214 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000214">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000214</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCI-neo DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000215 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000215">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000215</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000216 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000216">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000216</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV-1 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000217 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000217">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000217</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000026"/>
        <rdfs:label>obsolete pCMV4 DNA vaccine plasmid</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000218 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000218">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000213"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000218</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>hypersensitivity to chicken egg</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000219 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000219">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000219</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine component that is used to dissolve vaccine powder into liquid. The vaccine in a powder form has to be reconstituted by mixing vaccine powder with vaccine solvent before administered.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine diluent</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine liquid diluent</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine solvent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000220 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000220">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000220</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMVI.UBF3/2 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000221 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000221">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000221</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV-3FUB DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000222 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000222">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000222</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV-int DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000223 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000223">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000223</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV-LacZ DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000224">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000207"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000224</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>hypersensitivity to antibiotic</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000225 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000225">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000224"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000225</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>hypersensitivity to neomycin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000226 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000226">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000224"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000226</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>hypersensitivity to polymyxin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000227 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000227">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000207"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000227</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>reaction to previous vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000228 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000228">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000228</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine component that contains the solid form of all vaccine components. A vaccine can be reconstituted by mixing vaccine powder with vaccine solvent.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine powder</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000229">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000229</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a bacterial vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>bacterial vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000230 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000230">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000230</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV-LIC DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000231 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000231">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000231</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMVLuc DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000232">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000232</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCR3 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000233 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000233">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000227"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000233</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>life-threatening reaction to previous vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000234">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000234</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCR3.1 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000235 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000235">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000233"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000235</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>life-threatening reaction to previous influenza vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000236">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000236</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCR4-TOPO DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000237 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000237">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000224"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000237</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>hypersensitivity to gentamicin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000238 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000238">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000811"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000238</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>dominant epitope in vaccine</obo:IAO_0000118>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>vaccine dominant epitope</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000239 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000239">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000286"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000239</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced down-regulated gene expression</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000240 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000240">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000207"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000240</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>hypersensitity to gelatin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000178"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000241</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine prepraration process that is performed by heat inactivation of virulent pathogen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>inactivated vaccine preparation using heat inactivation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000242</metadata:prefixIRI>
        <obo:IAO_0000115>CFU reduction assay is an assay that measures the reduction of the colony forming units of infected pathogens in vaccine-vaccinated animals compared to nonvaccinated animals.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>CFU reduction assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000243 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000243">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000242"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000243</metadata:prefixIRI>
        <obo:IAO_0000115>assay of CFU reduction in spleen is a CFU reduction assay that is measured using the extracted spleen as the tissue for isolation of infected pathogens.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>assay of CFU reduction in spleen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000207"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000244</metadata:prefixIRI>
        <obo:IAO_0000116>Arginine is a conditionally essential amino acid, meaning most of the time it can be manufactured by the human body, and does not need to be obtained directly through the diet. The biosynthetic pathway however does not produce sufficient arginine, and some must still be consumed through diet. Individuals who have poor nutrition or certain physical conditions may be advised to increase their intake of foods containing arginine. Infants are unable to meet their requirements and thus arginine is nutritionally essential for infants.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>hypersensitity to arginine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000245">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001241"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000245</metadata:prefixIRI>
        <obo:IAO_0000115>A physical quality inhering in a bearer by virtue of the bearer being fit
to be eaten.</obo:IAO_0000115>
        <obo:IAO_0000116>Melanie has submitted this term and its two subclasses to obo:
http://sourceforge.net/tracker/?func=detail&amp;aid=2873643&amp;group_id=76834&amp;atid=595654</obo:IAO_0000116>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>edibility</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000246 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000246">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000245"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000246</metadata:prefixIRI>
        <obo:IAO_0000115>A quality of edibility that inheres in a bearer by virtue of the bearer being suitable for oral ingestion as food, drug, or vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:comment>This term may be submitted to PATO.</rdfs:comment>
        <rdfs:label>edible</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000247 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000247">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001029"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000247</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine efficacy is an efficacy of a vaccine in induction of protective immune response in vivo or protection against infection of a virulent pathogen. 
Specifically, vaccine efficacy (VE) is the percentage reduction in disease incidence attributable to vaccination, calculated by means of the following equation:
VE(%) = (U - V)/U x 100
where U = the incidence in unvaccinated people and 
V = the incidence in vaccinated people.
Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Editors: Plotkin S, et al. 2008. p1542-71.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccine efficacy</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000248 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000248">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000207"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000248</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>history of asthma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000249 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000249">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000632"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000249</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced antiviral neutralizing antibody response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000250">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000250</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcREV DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000251 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000251">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000251</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pgp.LAMP-1.  This plasmid has a CMV promoter and contains the human lysosomal-associated membrane protein-1 signal sequence.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pgp.LAMP-1 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 19356616</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000252 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000252">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000252</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pDRVISV1.0 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000253 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000253">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000253</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pECK DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000254 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000254">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000254</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pES.  This plasmid has a CMV promoter and contains a kanamycin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pES DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 19406186</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000207"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000255</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>usage of bronchodilator</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000256 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000256">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000256</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pET21a DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000257 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000257">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000257</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pET-28a DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000258 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000258">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000258</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pGA DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000259 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000259">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000259</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pGEX-3X DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000260 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000260">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000180"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000260</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced follicular dendritic cell activation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000261">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000207"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000261</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>usage of steroid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000262 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000262">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000262</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pIRES DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000263 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000263">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000263</metadata:prefixIRI>
        <obo:IAO_0000115>sodBFt is a live vaccine strain mutant of Francisella tularensis with reduced Fe-superoxide dismutase gene expression. Ref: PMID:18692537.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>sodB(Ft)</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16923916</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:18692537</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=55</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001818>55</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>C57BL/6 mice were vaccinated intranasally (i.n.) with the sodB(Ft) mutant and challenged i.n. with lethal doses of F. tularensis SchuS4. SodB(Ft) vaccinated mice following SchuS4 challenge exhibited significantly reduced bacterial burden in lungs, liver and spleen, regulated production of pro-inflammatory cytokines and less severe histopathological lesions compared to the LVS vaccinated mice. The sodB(Ft) vaccination induced a potent humoral immune response and protection against SchuS4 required both CD4 and CD8 T cells in the vaccinated mice</rdfs:comment>
        <rdfs:label>sodB(Ft) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000266 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000266">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_4"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000266</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>fungal disease</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000267 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000267">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005563"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000267</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that targets against a fungus infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_4751"/>
        <oboInOwl:hasDbXref>MeSH: D005657</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>fungal vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000271 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000271">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000271</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated Francisella tularensis vaccine. It is available in American Type Culture Collection with ATCC ID: 29684.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>F. tularensis vaccine LVS</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16912944</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:8757866</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=52</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>52</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis vaccine LVS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000272">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000272</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pIRES2 DsRed2 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000273">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000593"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000273</metadata:prefixIRI>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced T cell interferon-gamma production</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000274 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000274">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000274</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pING DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000275 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000275">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000275</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pJW24 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000276 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000276">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000276</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pJW4303 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000277 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000277">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000277</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pK0 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000278">
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000452"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000562"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000278</metadata:prefixIRI>
        <obo:IAO_0000115>To induce or modify protective or therapeutic immune response against a disease.</obo:IAO_0000115>
        <obo:IAO_0000116>PERSPN: Oliver He: There has been hot discussion about whether we use &apos;vaccine function&apos; or &apos;vaccine role&apos;. Vaccine role may not be the good term to use. Vaccine is designed to be &apos;vaccine&apos;, so it should be vaccine function. One special case is cowpox virus. The cowpox virus can be mixed with some liquid like water and used as a smallpox vaccine. In this case, people often say: the cowpox virus has a &apos;vaccine role&apos;. However, the cowpox virus vaccine is a processed material of a mix of the virus with water. The virus is a virus, it is not a vaccine per se. Therefore, vaccine role may not be an accurate term.</obo:IAO_0000116>
        <obo:IAO_0000117>Alan Ruttenburg</obo:IAO_0000117>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>vaccine function</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000279 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000279">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000279</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pK3 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000280">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000280</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pMV60 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000282 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000282">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000282</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pMAMneoBlue DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000283 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000283">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000283</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a herpesvirus as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>herpesvirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10292</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000284 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000284">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000284</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pMASIA DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000285 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000285">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000285</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pND DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000286 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000286">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000286</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine-induced host gene response</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced gene response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000287 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000287">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000287</metadata:prefixIRI>
        <obo:IAO_0000115>An immune system process that is realized in the calibrated response of the recipient to a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000116>The definition of this term is based on the definition of &apos;immune response (GO:0006955)&apos; . It is a child term of this GO term.</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine-induced host immune response</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced immune response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000288 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000288">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000288</metadata:prefixIRI>
        <obo:IAO_0000115>Process that specifies the organism&apos;s response to an administered vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine-induced host response</obo:IAO_0000118>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/781</obo:IAO_0000233>
        <obo:RO_0000057 rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <obo:RO_0000057 rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000289 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000289">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000290"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000289</metadata:prefixIRI>
        <obo:IAO_0000115>a process that specifies host response to a vaccine adjuvant.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>host response to vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000290 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000290">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000290</metadata:prefixIRI>
        <obo:IAO_0000115>Process that specifies host response to a vaccine component.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>host response to vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000291 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000291">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000290"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000291</metadata:prefixIRI>
        <obo:IAO_0000115>a process that specifies host response to a vaccine antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>host response to vaccine antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000292">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000290"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000292</metadata:prefixIRI>
        <obo:IAO_0000115>a process that specifies host response to a vaccine vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>host response to vaccine vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000293 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000293">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000293</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pND2 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000294 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000294">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000294</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pNGVL DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000295 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000295">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000295</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with human immunodeficiency virus that causes AIDS.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>AIDS vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>HIV vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>human immunodeficiency virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000297 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000297">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000297</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pNL3-gal DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000298 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000298">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000298</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pN4a-gal DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000299 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000299">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000299</metadata:prefixIRI>
        <obo:IAO_0000115>A legal organization that represents an association of people with a specific objective.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Company</obo:IAO_0000119>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>company</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000300 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000300">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001135"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000300</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis strain VTRM1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=135</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>135</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis strain VTRM1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000301 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000301">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000301</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pRc/CMV DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000302 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000302">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000302</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pRc/CMV2 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000303 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000303">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001136"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000303</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. suis VTRS1</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella suis strain VTRS1</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17428946</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=136</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>136</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella suis strain VTRS1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000304 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000304">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000304</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pRK DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000305 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000305">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000305</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pRSV DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000306 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000306">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000306</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pRSV0 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000307 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000307">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000307</metadata:prefixIRI>
        <obo:IAO_0000115>KKF24 is a recombinant strain of Francisella novicida U112 with iglC mutation (F. novicida delta-iglC::ermC). PMID:14680699.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>KKF24</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16552035</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=60</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001818>60</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An iglC mutant is highly attenuated in mice. Inoculated mice were challenged 30 days later with wild type F. tularensis and were highly protected</rdfs:comment>
        <rdfs:label>KKF24 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000308 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000308">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000308</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>F. tularensis vaccine LVS LPS</obo:IAO_0000118>
        <obo:IAO_0000118>F. tularensis vaccine LVS lipopolysaccharide</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10722593</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=58</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001818>58</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis vaccine LVS LPS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000309 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000309">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000309</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000632"/>
        <rdfs:label>obsolete vaccine-induced antibody mediated immune response</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000310">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000179"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003025"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000850"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000310</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine additive that stabilizes the vaccine emulsification manufacturing process and makes emulsion of the vaccine easier. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/pubmed/16337664</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0003025"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Emulsifiers help bind ingredients together and keep them from separating, most commonly with oil and water. An emulsifier is also a surfactant that reduces the surface tension of a liquid and results in an easier, smoother spread. Reference: http://www.wisegeek.org/what-is-polysorbate-80.htm</rdfs:comment>
        <rdfs:label>vaccine emulsifier</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000311 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000311">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001223"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16412"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000311</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis lipopolysaccharide vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=137</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16412"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>137</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis lipopolysaccharide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000312 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000312">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001223"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000312</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis LPS-GBOMP noncovalent complex vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>B. melitensis LPS-GBOMP subunit vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:8723881</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=307</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>307</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis LPS-GBOMP noncovalent complex vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000313 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000313">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000313</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSC65 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000314 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000314">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000314</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSG2 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000315 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000315">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000315</metadata:prefixIRI>
        <obo:IAO_0000115>A whole organism vaccine that uses an inativated pathogen organism as its component.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>inactivated organism vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>killed vaccine</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000316 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000316">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000316</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSG5 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000317 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000317">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000317</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Psin DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000318 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000318">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000318</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pTARGET DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000319</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pTH DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000320">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000320</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pTHamp DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000321 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000321">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001225"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000154"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000321</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus DNA vaccine expressing BCSP31, SOD and L7/L12</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17570767</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=211</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0000154"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>211</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus DNA vaccine encoding BCSP31, SOD and L7/L12</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000322 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000322">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000322</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pTR600 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000323 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000323">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000956"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010928"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000323</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>recombinant B. abortus L7/L12 vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:8873388</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=111</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010928"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>111</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus conjugate vaccine using L7/L12</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000324 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000324">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000324</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pTVG4 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000325 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000325">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001226"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010939"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000325</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis DNA vaccine encoding Omp31</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17428946</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=293</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010939"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>293</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis DNA vaccine encoding Omp31</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000326 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000326">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000326</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pUC18 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000327 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000327">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000327</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pUC19 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000328 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000328">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000328</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pV1J DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000329 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000329">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2099"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000604"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2099"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000329</metadata:prefixIRI>
        <obo:IAO_0000115>bacterial vaccine that protect against Mycoplasma hyopneumoniae infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2099"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma hyopneumoniae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000330 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000330">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000245"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000330</metadata:prefixIRI>
        <obo:IAO_0000115>A quality of edibility that inheres in a bearer by virtue of the bearer being not suitable for oral ingestion.</obo:IAO_0000115>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>inedible</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000331 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000331">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000331</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pVCL(pCXN2-mVIN) DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000708"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000062"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000903"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000332</metadata:prefixIRI>
        <obo:BFO_0000062 rdf:resource="http://purl.obolibrary.org/obo/VO_0000903"/>
        <obo:IAO_0000115>tertiary vaccination is a vaccination that is performed at the third time in a row.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Thom Todd</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>tertiary vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000333 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000333">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2759"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000333</metadata:prefixIRI>
        <obo:IAO_0000115>Protozoa are a diverse group of unicellular eukaryotic organisms,[1] many of which are motile. Originally, protozoa had been defined as unicellular protists with animal-like behavior, e.g., movement. Protozoa were regarded as the partner group of protists to protophyta, which have plant-like behaviour, e.g., photosynthesis.(http://en.wikipedia.org/wiki/Protozoa)</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>Protozoa</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000334">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000334</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pVR1012 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000335 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000335">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003247"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000335</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccination site that is used for injection of a vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>vaccine injection site</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000336 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000336">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000336</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pVR1012x/s DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000337 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000337">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000337</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pWRG1644 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000338 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000338">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001135"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0002561"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000338</metadata:prefixIRI>
        <obo:IAO_0000115>A B. melitensis vaccine that is recombinant B. melitensis Rev. 1 vaccine with the bp26 deletion. It has similar vaccine efficacy to Rev. 1. Its advantage compared to Rev. 1 is that this feature of bp26 deletion promotes diagnosis. PMID:17070627.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis bp26 deletion vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella CGV26</obo:IAO_0000118>
        <obo:IAO_0000118>CGV26</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16519974</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=295</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/VO_0002561"/>
        <obo:VO_0001818>295</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis bp26 deletion vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000339 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000339">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000339</metadata:prefixIRI>
        <obo:IAO_0000115>A spontaneous mutant of the SCHU S4 strain that protects against virulent F. tularensis infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>F. tularensis vaccine FSC043</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16299332</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=57</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001818>57</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis vaccine FSC043</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000340 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000340">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000340</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that inject the material(such as vaccines, allergens) directly into a muscle.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>intramuscular injection route</obo:IAO_0000118>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intramuscular route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000341 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000341">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000341</metadata:prefixIRI>
        <obo:IAO_0000115>A rounte of administration that located in nose.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intranasal route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000342 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000342">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000341"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000342</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intranasal route by drop</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000343 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000343">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000341"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000343</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intranasal route by spray</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000344 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000344">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000344</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that located in the peritoneum.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intraperitoneal route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000345 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000345">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001135"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000345</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis WR201</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=308</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>308</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis WR201 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000346 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000346">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000346</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pWRG7077 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000347 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000347">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
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            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000347</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus bacA mutant</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella abortus bacA mutant</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17196866</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=301</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>301</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus bacA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000348 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000348">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000689"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000348</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=452</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm181975.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>452</obo:VO_0001818>
        <obo:VO_0003160>Active immunization of persons ages 6 months and older against influenza disease caused by pandemic (H1N1) 2009 virus.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM182401.pdf</obo:VO_0003161>
        <obo:VO_0003162>125254</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A (H1N1) 2009 Monovalent vaccine (CSL Limited)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000349 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000349">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001178"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003211"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000341"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000694"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000349</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=456</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm181970.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000341"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>456</obo:VO_0001818>
        <obo:VO_0003160>Active immunization of individuals 2-49 years of age against influenza disease caused by pandemic (H1N1) 2009 virus.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM182406.pdf</obo:VO_0003161>
        <obo:VO_0003162>125020</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A (H1N1) 2009 Monovalent vaccine (MedImmune LLC)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000350 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000350">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000350</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine role that is characteristic of a live virulent vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>live virulent vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000351 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000351">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000351</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is PCPP salt.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Adjumer</obo:IAO_0000118>
        <obo:IAO_0000118>PCPP salt</obo:IAO_0000118>
        <obo:IAO_0000118>polyidi (carboxylatophenoxy) lphosphazene</obo:IAO_0000118>
        <obo:IAO_0000118>polyphosphazene</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:75551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Adjumer vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000352 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000352">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000352</metadata:prefixIRI>
        <obo:IAO_0000115>Megan Egg is a Salmonella vaccine that that consists of a double gene-deleted S. enterica serovar Typhimurium strain and is formulated fro immunization of pullets. Megan Egg contains the same Megan Vac1 organism but Megan Vac1 is used for younger birds (broilers).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Megan Egg</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=752</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.fda.gov/ohrms/dockets/dockets/00n0504/00N-0504_emc-001650-02.pdf</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>752</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Megan Egg vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000353 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000353">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000353</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pWRM DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000354 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000354">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000354</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16481077</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/697"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0004146"/>
        <rdfs:label>obsolete B. ovis microparticle subunit vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000355 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000355">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000355</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pzz DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000356 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000356">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000356</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pME18100 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000357 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000357">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000357</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pVIVO2 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000358 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000358">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001221"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000358</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Brucella rSurA protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella recombinant SurA protein</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17686554</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=445</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>445</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella recombinant SurA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000359">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000359</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a lentivirus as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>lentivirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11646</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000360 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000360">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000360</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcDNA1.1/Amp DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000361 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000361">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000180"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000361</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced leukocyte activation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000362 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000362">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
                    </owl:Restriction>
                </owl:intersectionOf>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001485"/>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000362</metadata:prefixIRI>
        <obo:IAO_0000115>a licensed human vaccine that is licensed in the USA.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>FDA licensed vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm093833.htm</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>USA licensed human vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000363 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000363</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is licensed for commercial use.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000364 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000364">
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000364</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pRK7 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000365 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000365">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000365</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>lipopolysaccharide of pathogen organism as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000366 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000366">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000366</metadata:prefixIRI>
        <obo:IAO_0000115>A particulate antigen delivery system vaccine adjuvant that contains particles made up of concentric lipid membranes containing phospholipids and other lipids in a bilayer configuration separated by aqueous compartments. It is a relatively stable but non-covalently-bound complex of saponin adjuvant Quil-A, cholesterol and amphipathic antigen in a molar ratio of approximately 1:1:1. The spectrum of viral capsid antigens and non-viral amphipathic antigens of relevance for human vaccination, incorporated into ISCOMs, comprises influenza, measles, rabies, gp340 from EB-virus, gp120 from HIV, Plasmodium falciparum and Trypanosoma cruzi.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.vaccination.inoz.com/adjuvants.html</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>liposome-based vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000367 -->

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                    </owl:Restriction>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000367</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is made from microbes that have been attenuated (weakened) in the laboratory so that they can&apos;t cause disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>attenuated vaccine</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000368 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000368">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000506"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000368</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine organism that is live</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000086 rdf:resource="http://purl.obolibrary.org/obo/VO_0001145"/>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>live vaccine organism</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000370 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000370">
        <owl:equivalentClass>
            <owl:Class>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000370</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that uses a live, pathogenic (disease-causing) microorganism to stimulate the immune system.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000350"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live virulent vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000371 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000371">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000371</metadata:prefixIRI>
        <obo:BFO_0000062 rdf:resource="http://purl.obolibrary.org/obo/VO_0000332"/>
        <obo:IAO_0000115>quaternary vaccination is a vaccination that is performed at the fourth  time in a row.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Thom Todd</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>quaternary vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000372 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000372">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000372</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is used to improve conception.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>profertility vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000373 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000373">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000373</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17686554</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=292</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>292</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella recombinant DnaK protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000374 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000374">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000374</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>divalent DNA B. abortus vaccine using L7/L12 and Omp16</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16622210</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=302</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>302</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>divalent DNA Brucella abortus vaccine using L7/L12 and Omp16</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000375 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000375">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000375</metadata:prefixIRI>
        <obo:IAO_0000112>&apos;Mycobacterium avium relA mutant vaccine&apos; includes a gene mutation of relA from virulent Mycobacterium avium. </obo:IAO_0000112>
        <obo:IAO_0000115>A live attenuated vaccine prepraration process that is performed by mutation of a gene(s) from a virulent pathogen.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>live attenuated vaccine preparation by gene mutant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000376 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000376">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000376</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that is through the membrane covering the muscles and nerves at the back of the eyeball</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>subtenon route</rdfs:label>
        <rdfs:seeAlso>http://ncim.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20MetaThesaurus&amp;code=CL426248</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000377 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000377">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000886"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000377</metadata:prefixIRI>
        <obo:IAO_0000115>An oral route of administration that is underneath the tongue.</obo:IAO_0000115>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>sublingual route</rdfs:label>
        <rdfs:seeAlso>http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C38300</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000378 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000378">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000378</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intravaginal route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000379 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000379">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000379</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000378"/>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>intravaginal vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000380 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000380">
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000380</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000376"/>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:comment>YH</rdfs:comment>
        <rdfs:label>subtenon vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000381 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000381">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003021"/>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000381</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000377"/>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>sublingual vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000382 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000382">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003021"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000382</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000953"/>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>pharyngeal mucosal vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000383 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000383">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000273"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000383</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine-induced T cell interferon-gramm production that results from the addition of a vaccine adjuvant</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced, adjuvant boosted T cell interferon-gramm production</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000384 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000384">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001342"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000384</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:18472194
</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>IL-15 plasmid vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000385">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001225"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000385</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus DNA vaccine encoding L7/L12 and P39</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16537031</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus DNA vaccine encoding L7/L12 and P39</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000386">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000386</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>attenuated Brucella abortus with deletion of znuA</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16790759</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=288</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>288</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>attenuated Brucella abortus with deletion of znuA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000387 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000387">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000408"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000387</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>mucosal immune response to vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000388 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000388">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000388</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant that is derived from E. coli heat labile toxin LT.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>E. coli LT toxin derived vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000389 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000389">
        <owl:equivalentClass>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001465"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000389</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Feline panleukopenia virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10786"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline panleukopenia virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000390 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000390">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000390</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing birds.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001461"/>
        <rdfs:label>obsolete birds vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000391 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000391">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000391</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Leptospira spp. infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leptospira spp. vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000392 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000392">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000568"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000392</metadata:prefixIRI>
        <obo:IAO_0000115>a Campylobacter bacterial vaccine that is used to protect against Campylobacter fetus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter fetus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000393 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000393">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000766"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000393</metadata:prefixIRI>
        <obo:IAO_0000115>bacterial vaccine that is used to protect against Pseudomonas aeruginosa infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudomonas aeruginosa vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000394 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000394">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000587"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000394</metadata:prefixIRI>
        <obo:IAO_0000115>Bordetella bacterial vaccine that is used to protect against Bordetella bronchiseptica infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella bronchiseptica vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000395 -->

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        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000506"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000395</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>a vaccine organism that is inactived/killed</obo:IAO_0000118>
        <obo:IAO_0000118>killed vaccine organism</obo:IAO_0000118>
        <obo:RO_0000086 rdf:resource="http://purl.obolibrary.org/obo/VO_0000211"/>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>inactivated vaccine organism</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000396 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000396</metadata:prefixIRI>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed rabbit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000397 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000397">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000148"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000397</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>neutralizing antibody role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000398 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000398">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000398</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated Brucella melitensis vaccine that is composed of live Brucella melitensis attenuated mutant vjbR::Tn5 (BMEII1116) delivered using a microsphere delivery system.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>microencapsulated B. melitensis mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:18362129</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=304</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>304</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>The deletion of vjbR gene in Brucella melitensis strain 16M made a live attenuated vaccine and provided significance protection against mice</rdfs:comment>
        <rdfs:label>microencapsulated Brucella melitensis mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000399 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000383"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000399</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine-induced adjuvant boosted T cell interferon-gramm production that results from the addition of a IL-15 vaccine adjuvant</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:  18472194</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced T cell interferon-gramm production boosted by IL-15 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000400 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000400</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that contains one vaccine for priming and at least one other vaccine for boosting. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>prime-boost vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000401 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000401">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000401</metadata:prefixIRI>
        <obo:IAO_0000115>A prime-boost vaccine that contains one DNA vaccine for priming and at least one other vaccine for boosting. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>prime-boost vaccine with DNA vaccine priming</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000402 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000402</metadata:prefixIRI>
        <obo:IAO_0000118>AIDSVAX</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:12848591</obo:IAO_0000119>
        <obo:IAO_0000119>http://en.wikipedia.org/wiki/AIDSVAX</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AIDSVAX vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000403 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000403">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001221"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000403</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>complex of porin and S-LPS from  B. abortus strain 2308</obo:IAO_0000118>
        <obo:IAO_0000118>porin-S-LPS from B. abortus strain 2308</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:2844673</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=291</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>291</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>porin-S-LPS from Brucella abortus strain 2308 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000404 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000404">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000404</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus RB51WboA</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella abortus RB51WboA</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15327798</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=13</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>13</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus RB51WboA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000405 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000405</metadata:prefixIRI>
        <obo:IAO_0000115>The AIDSVAX that is bicovalent vaccine including two kinds of gp120 protein: MN rgp120/HIV-1 and GNE8 rgp120/HIV-1 (MN and GNE8 are strain names).</obo:IAO_0000115>
        <obo:IAO_0000116>link to another well-known study: VAX004</obo:IAO_0000116>
        <obo:IAO_0000116>linkto the clinical trail database by : ClinicalTrials.gov Identifier: NCT00002441</obo:IAO_0000116>
        <obo:IAO_0000118>AIDSVAX B/B</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AIDSVAX B/B vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000406 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000406</metadata:prefixIRI>
        <obo:IAO_0000118>AIDSVAX B/E</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AIDSVAX B/E vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000407 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000407">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000957"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000407</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>recombinant O. anthropi 49237SOD</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11953393</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=113</obo:IAO_0000119>
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        <obo:VO_0001818>113</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant O. anthropi 49237SOD vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000408 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000408">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000287"/>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>organ or tissue specific immune response to vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000409 -->

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        <owl:equivalentClass>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000409</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed horse vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000410 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000410</metadata:prefixIRI>
        <obo:IAO_0000115>Pandemrix is an influenza vaccine for influenza pandemics, such as the H1N1 2009 flu pandemic colloquially called the swine flu. The vaccine was developed by GlaxoSmithKline and patented in September 2006.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118>Pandemrix H1N1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3957</obo:IAO_0000119>
        <obo:IAO_0000119>http://en.wikipedia.org/wiki/Pandemrix</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3957</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>ATC code:J07BB02</rdfs:comment>
        <rdfs:comment>As well as the active antigen derived from A/California/7/2009 (H1N1), the vaccine contains an immunologic adjuvant AS03 which consists of DL-alpha-tocopherol (vitamin E), squalene and polysorbate 80. Thiomersal (thimerosal) is added as a preservative. Being manufactured in chicken eggs, it contains trace amounts of egg proteins. Additional important non-medicinal ingredients are formaldehyde, sodium deoxycholate, and sucrose. (http://en.wikipedia.org/wiki/Pandemrix)</rdfs:comment>
        <rdfs:label>Pandemrix vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000411 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000411</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis Bp26 and Tf protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>B. melitensis Bp26 and trigger factor</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17239499</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=300</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>300</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis Bp26 and Tf protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000412 -->

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            </owl:Restriction>
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            </owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000412</metadata:prefixIRI>
        <obo:IAO_0000115>A Brucella subunit vaccine that uses recombinant Brucella melitensis 16M P39, a putative periplasmic binding protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis P39 recombinant protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11447155</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=198</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>198</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis P39 recombinant protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000413 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000413">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000413</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>rBLSOmp31</obo:IAO_0000118>
        <obo:IAO_0000118>recombinant chimera BLSOmp31</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17442465</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=212</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>212</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant chimera BLSOmp31 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000414 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000414">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000578"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000414</metadata:prefixIRI>
        <obo:IAO_0000115>Panvax is an H1N1 unadjuvanted monovalent vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Panvax</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.infowars.com/h1n1-panvax-training-powerpoint-received-by-health-care-workers-in-australia/</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Panvax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000415 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000415">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000617"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000415</metadata:prefixIRI>
        <obo:IAO_0000115>A role inheres in a material entity, that has been added into a vaccine&apos;s formulation by the manufacture for a specific purpose. For example: adjuvant to enhance the effect of immunogen, perservatives, stablizers and those materials added for affecting PH and isotonicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>Page 73, Chapter 6, Vaccine, 5th Edition. EXPERT CONSULT by Plotkin SA., et. al. 2008</obo:IAO_0000119>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine additive role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000416 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000416">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000416</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that is located in the vein</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Thom Todd</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intravenous route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000417 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000417">
        <owl:equivalentClass>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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                    </owl:Restriction>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005563"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000417</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against some protozoan disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>parasite vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>parasitic vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000333"/>
        <oboInOwl:hasDbXref>MeSH: D016052</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>protozoan vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000418 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000418</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0015064"/>
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        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0015071"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine injection 0.5mL vial</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm176044.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0001256"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003049"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:hasDbXref>SNOMEDCT: 416532007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1563043</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Product Name: Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine  injection 0.5mL vial</rdfs:comment>
        <rdfs:comment>Trade Name: Menactra</rdfs:comment>
        <rdfs:label>Menactra injection 0.5mL vial</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000419 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000419">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000669"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8659"/>
            </owl:Restriction>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000419</metadata:prefixIRI>
        <obo:IAO_0000115>a Varicella-zoster virus vaccine that is live attenuated.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8659"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella-zoster virus live vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000420 -->

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        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
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                    </owl:Class>
                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000420</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine component that originates from an organism such as a pathogen or a modified organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pathogen organism component in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000421 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000421">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001225"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000421</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus pcDNA-BLS</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=199</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>199</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus pcDNA-BLS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000422 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000177"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000422</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is used against melanoma, a malignant tumor of melanocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Melanoma</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <oboInOwl:hasDbXref>SNOMEDCT:373869007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0796561</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000423 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000423">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000423</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>escheriosome-encapsulated B. abortus L7/L12</obo:IAO_0000118>
        <obo:IAO_0000118>escheriosome-mediated delivery of B. abortus L7/L12</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17931756</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=298</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>298</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>escheriosome-mediated delivery of Brucella abortus L7/L12 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000424 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000424</metadata:prefixIRI>
        <obo:IAO_0000115>a pneumococcal vaccine that is formed using polyvalent polysaccharides</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.who.int/vaccines/en/pneumococcus.shtml</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>The most common form of the polyvalent pneumococcal vaccine is called the protein-polysaccharide combinations which is known as conjugate vaccines and contain 7-11 selected polysaccharides bound to a protein carrier. The protein-polysaccharide combinations are able to induce a T-cell dependent immune response. These vaccines are likely to be protective even in children under two years of age, and may reduce pneumococcal transmission through a herd effect.</rdfs:comment>
        <rdfs:label>polyvalent pneumococcal vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000425 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000425">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000770"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000425</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/pubmed/10700309</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1279"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>a Staphyloccoccus vaccine that is made using engineered toxoid.</rdfs:comment>
        <rdfs:label>Staphylococcus toxoid vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000426 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000426">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000426</metadata:prefixIRI>
        <obo:IAO_0000115>period of persistence of vaccine induced immune response is a temporal interval during which a vaccine-induced immune response continuously exists. This term is related to the process &apos;persistence of vaccine induced immune response&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>temporal region</oboInOwl:inSubset>
        <rdfs:label>period of persistence of vaccine induced immune response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000427 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000427">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000596"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000427</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine clinical trial that investigates the safety profile of a vaccine in a small group (10-50) of healthy volunteers.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>phase 1 vaccine trial</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000428 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000428">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000596"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000428</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine clinical trial that studies vaccine efficacy with a target population (numbering 50-100). Different dosage levels will also be explored at this stage to determine the optimum dose.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>phase 2 vaccine trial</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000429 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000429">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000596"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000429</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine clinical trial that takes the trial to a large-scale safety and efficacy study in a relevant patient population, usually in excess of 3,000.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>phase 3 vaccine trial</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000430 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000430">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000596"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000430</metadata:prefixIRI>
        <obo:IAO_0000115>The final stage of vaccine clinical evaluation. Phase IV occurs after a vaccine or therapy is licensed and is being used by large numbers of people. These studies are not always required or completed.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>phase 4 vaccine trial</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000431 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000431">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000431</metadata:prefixIRI>
        <obo:IAO_0000115>Seven F. tularensis proteins including IglC (rLm/iglC) were expressed in recombinant L. monocytogenes (rLm) vaccines. These 7 F. tularensis proteins are: AcpA, Bfr, DnaK, GroEL, IglC, Pld and KatG from SchuS4 strain.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>F. tularensis DNA vaccine rLm/iglC</obo:IAO_0000118>
        <obo:IAO_0000118>rLm/iglC</obo:IAO_0000118>
        <obo:IAO_0000118>rLm/iglC vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=929</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011072"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001818>929</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis DNA vaccine rLm/iglC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000432 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000432">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010916"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000432</metadata:prefixIRI>
        <obo:IAO_0000115>A subunit nontypeable H. influenzae vaccine that uses Hap protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>nontypeable H. influenzae Hap protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15557618</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=170</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010916"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001818>170</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae Hap protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000433 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000433">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000433</metadata:prefixIRI>
        <obo:IAO_0000115>Smallpox virus vaccine that uses vaccinia virus. The vaccine is made from a laboratory strain of the live vaccinia virus that has been attenuated, or weakened, so that it stimulates an immune response without causing the severe disease associated with smallpox.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Vaccinia</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Vaccinia virus is well known for its role as a vaccine that helped eradicate the smallpox disease, making it the first human disease to be successfully eradicated by science.</rdfs:comment>
        <rdfs:label>vaccinia virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000434 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000434">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000434</metadata:prefixIRI>
        <obo:IAO_0000115>Mixed Bacterial Vaccine (MBV, Coley&apos;s Toxins) is a historical, vaguely defined preparation of heat-inactivated Streptococcus pyogenes and Serratia marcescens used as non-specific immunotherapy in the treatment of cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22847809</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6314</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6314</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Mixed Bacterial Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000435 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000435">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003674"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000435</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine vector that is a DNA plasmid used to deliver the genetic code into the cells within the body. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine plasmid vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000436 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000436">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001226"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000436</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis DNA vaccine encoding Omp31 boosted with Omp31</obo:IAO_0000118>
        <obo:IAO_0000118>pCIBLSOmp31</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=446</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>446</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis DNA vaccine encoding Omp31 boosted with Omp31</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000437 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000437">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_476"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_476"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000437</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Moraxella bovis infection. Moraxella bovis is a Gram-negative, aerobic, oxidase-positive diplococcus that is implicated in infectious bovine keratoconjunctivitis, an eye disease of cattle, also colloquially known as Pink Eye.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Moraxella_bovis</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_476"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Moraxella bovis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000438 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000438">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000437"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_476"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000438</metadata:prefixIRI>
        <obo:IAO_0000115>a Moraxella bovis vaccine that is prepared using a bacterial bacterin.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_476"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Moraxella bovis bacterin vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000439 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000439">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000812"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000439</metadata:prefixIRI>
        <obo:IAO_0000115>a USA licensed vaccine role that indicates the vaccine is for veterinary uses.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>USDA licensed vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000440 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000440">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000440</metadata:prefixIRI>
        <obo:IAO_0000112>WEB: http://news.prnewswire.com/ViewContent.aspx?ACCT=109&amp;STORY=/www/story/09-15-2009/0005094621&amp;EDATE @2009/10/06</obo:IAO_0000112>
        <obo:IAO_0000112>WEB: http://www.examiner.com/x-7707-Infectious-Disease-Examiner~y2009m9d15-News-Release-H1N1-vaccines-get-FDA-approval-expected-to-be-available-in-4-weeks @2009/10/06. H1N1 vaccines get FDA approval. Food and Drug Administration announced today that it has approved four vaccines against the 2009 H1N1 influenza virus. Obtaining FDA licensure of this vaccine for A (H1N1) pandemic response is a key milestone that will enable Sanofi Pasteur to provide a licensed vaccine to the U.S. government to support pandemic immunization efforts</obo:IAO_0000112>
        <obo:IAO_0000115>vaccine approval process is a processual entity that involves approval of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Alan Ruttenburg</obo:IAO_0000117>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine product approval process</obo:IAO_0000118>
        <obo:IAO_0000119>WEB:  http://energycommerce.house.gov/images/stories/Documents/PDF/publications/109_health.pdf @2009/10/06. This is the US Health Law which includes a section about vaccine.</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.hhs.gov/nvpo/factsheets/fs_tableII_doc2.htm @2009/10/06 #Following the FDA&apos;s review of a license application, the sponsor and the FDA may present their findings to the FDA&apos;s Vaccines and Related Biological Products Advisory Committee (VRBPAC). This non-FDA expert committee (scientists, physicians, biostatisticians, and a consumer representative) provides advice to the Agency regarding the safety and efficacy of the vaccine for the proposed indication.</obo:IAO_0000119>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine approval process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000441 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000441">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000441</metadata:prefixIRI>
        <obo:IAO_0000115>Role of a material entity in an investigation, which has not been experimentally or clinically verified to induce a protection or treatment in vivo in a recipient organism. </obo:IAO_0000115>
        <obo:IAO_0000116>This role should be a subclass of &apos;test substance role&apos;, which will be mireoted from OBI by OntoFox.</obo:IAO_0000116>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine candidate role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000442 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000442">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000189"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000442</metadata:prefixIRI>
        <obo:IAO_0000115>CFU measurement assay is an assay that measures the colony forming unit (CFU) of a bacterium in a specific location (e.g., spleen of a mouse).</obo:IAO_0000115>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000189"/>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>CFU measurement assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000443 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000443">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000443</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that measues the vaccine effectiveness.  It is assessed with respect to prevention of the disease against which the vaccine is given. 
One simple method to estimate vaccine effectiveness is to use routine data on notifications of disease cases in vaccinated and unvaccinatted children and to compare the porportion of cases vaccinated with the vaccine covervage among the same age group in the general population. If p is the proportion vaccinated in the population and c is the proportion of cases reported to be vaccinated, then
VE = (p-c)/p(1-c) x 100%.</obo:IAO_0000115>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>Hadler TC, et al. Immunization in developing countries. In: Vaccines. Editors: Plotkin S, et al. 2008. p1542-71.</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Influenza_vaccine</obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine effectiveness rate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000444 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000444">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000440"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000444</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine licensing is a vaccine approval process that involves in licensing a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine licensing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000446 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000446">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001468"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001468"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000446</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed chicken vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000447 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000447">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000447</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses an poxvirus as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>poxvirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10240</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000448 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000448">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000448</metadata:prefixIRI>
        <obo:IAO_0000115>a Salmonella vaccine against infection with S. paratyphi, which causes paratyphoid fevers. Paratyphoid fevers are a group of enteric illnesses caused by serotypic strains of the Salmonella genus of bacteria, S. Paratyphi.</obo:IAO_0000115>
        <obo:IAO_0000118>paratyphoid vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>WED: http://en.wikipedia.org/wiki/Paratyphoid_fever</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella paratyphi vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000449 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000449">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000438"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_476"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000893"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000449</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Moraxella Bovis Bacterin Piliguard Pinkeye-1 Trivalent </obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.jefferspet.com/%252332moraxella-bovis-bacterin-piliguard-pinkeye-1-trivalent/camid/liv/cp/16435/</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_476"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Moraxella Bovis Bacterin Piliguard Pinkeye-1 trivalent vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000450 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000450">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000108"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000450</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Brucella vaccine using nonpathogenic alphaproteobacteria</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17715332</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=275</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>275</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NPAP Brucella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000451 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000451">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000749"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000451</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Parainfluenza 3 virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parainfluenza 3 virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000452 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000452">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000278"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000495"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000496"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000452</metadata:prefixIRI>
        <obo:BFO_0000054 rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <obo:BFO_0000054 rdf:resource="http://purl.obolibrary.org/obo/VO_0000495"/>
        <obo:BFO_0000054 rdf:resource="http://purl.obolibrary.org/obo/VO_0000496"/>
        <obo:IAO_0000115>A vaccine function realized by the process of vaccination and leading to induction of an adaptive immune response to prevent a specific disorder.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>prophylactic vaccine function</obo:IAO_0000118>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>preventive vaccine function</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000453 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000453">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000572"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000453</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>prime boost regimen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000454 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000454">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001156"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000454</metadata:prefixIRI>
        <obo:IAO_0000116>Colibacillosis, caused by avian pathogenic Escherichia coli (APEC), is a major problem for the poultry industry in the world.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16863080</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=134</obo:IAO_0000119>
        <obo:VO_0001818>134</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>APEC vaccine using GST-Iss fusion protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000455 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000455">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000455</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine that is used for prevention against a disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>prophylactic vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000456">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001029"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000456</metadata:prefixIRI>
        <obo:IAO_0000115>Protection efficacy is an efficiency that is associated with protection by a biological product (e.g., vaccine) against a disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>protection efficacy</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000457 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000457">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000237"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000457</metadata:prefixIRI>
        <obo:IAO_0000115>An antigen that stimulates protective immunity when used in vivo.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>protective antigen role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000458 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000458">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000458</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. coli heat-labile enterotoxin B-subunit (LB-T) vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11500434</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli LB-T vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000459 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000459</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:14670317</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=274</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010940"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>274</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli O157:H7 subunit vaccine expressing Esps and Tir</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000460 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000460</metadata:prefixIRI>
        <obo:IAO_0000115>an influenza virus vaccine against equine influenza viral infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>equine influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000461 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000461</metadata:prefixIRI>
        <obo:IAO_0000115>An influenza vaccine for avian use</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000463 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000463</metadata:prefixIRI>
        <obo:IAO_0000115>Bacterial vaccine against infection with Coxiella burnetii which causes Q fever</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Q fever vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Q_fever</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coxiella burnetii vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000464 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>protein of pathogen organism as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000465 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000465</metadata:prefixIRI>
        <obo:IAO_0000115>a S. aureus vaccine that uses bacterin as the protective antigen. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <oboInOwl:hasDbXref>SNOMEDCT: 52974007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI: C0310856</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus bacterin vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000466 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000466</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17188785</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=125</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>125</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>soybean-expressed E. coli LTB vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000467 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000467</metadata:prefixIRI>
        <obo:IAO_0000115>a S. aureus vaccine that uses the bacterial phage lysate as the protective antigen. </obo:IAO_0000115>
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        <oboInOwl:hasDbXref>SNOMEDCT: 34679007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI: C0311044</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus phage lysate vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000468 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000468">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000468</metadata:prefixIRI>
        <obo:IAO_0000115>a Mycoplasma gallisepticum vaccine that uses bacterin as the protective antigen</obo:IAO_0000115>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma gallisepticum bacterin vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000469 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000469">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
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        <obo:IAO_0000115>a bacterial vaccine that uses bacterin from a bacterial strain isolated from a herd with a purpose to generate hard-specific vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://addisonlabs.com/products/autogenous-bacterins.php</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>autogenous bacterin vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000470 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000470">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000469"/>
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        <obo:IAO_0000115>an autogenous bacterin vaccine that is prepared for poultry use. </obo:IAO_0000115>
        <obo:IAO_0000119>WEB: http://www.hygieialabs.com/autopoultry.html</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>autogenous poulty bacterin vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000471 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000471">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000471</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>nontypeable H. influenzae vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000472"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000472 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000472</metadata:prefixIRI>
        <obo:IAO_0000115>Nontypeable Haemophilus influenzae (NTHi) is a nonencapsulated Haemophilus influenzae (a gram-negative bacterium). It is the cause of a number of human respiratory tract diseases, such as otitis media, sinusitis, bronchitis, and pneumonia.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>NTHi</obo:IAO_0000118>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>nontypeable Haemophilus influenzae</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000473 -->

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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000473</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>non-typeable H. influenzae rLP4/rLP6 and Moraxella catarrhalis UspA2 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>rLP4/rLP6/UspA2</obo:IAO_0000118>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=169</obo:IAO_0000119>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010914"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>169</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae rLP4/rLP6 and Moraxella catarrhalis UspA2 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000474 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000474">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000471"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000474</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>killed nontypeable H. influenzae whole-cell vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:1859055</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:1953532</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:2184330</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:2867396</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=163</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>163</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>killed nontypeable Haemophilus influenzae whole-cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000475 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000475">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000475</metadata:prefixIRI>
        <obo:IAO_0000115>a Rabies virus vaccine against Rabies in animal</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>animal Rabies vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000477 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000477">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000477</metadata:prefixIRI>
        <obo:IAO_0000115>a Rabies virus vaccine against Rabies in human</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>human Rabies vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000478 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000478">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010944"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000478</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:14688094</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:17258324</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=122</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010944"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>122</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli vaccine using intimin polypeptide</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000479 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000479">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000479</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>nontypeable H. influenzae cell membrane vaccine (CM-Hi)</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10353870</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=194</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001818>194</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae cell membrane vaccine (CM-Hi)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000480 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000480">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000471"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10150"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000480</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Nontypeable H. influenzae lipooligosaccharide-tetanus toxoid  conjugate vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>nontypeable H. influenzae LOS-TT conjugate vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:12706701</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9353024</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=164</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>164</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10150"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae LOS-TT conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000481 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000481">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000481</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17145948</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=127</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>127</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli subunit vaccine using IroN</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000482 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000482">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000717"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000482</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation process that uses recombinant molecular technology to prepare recombinant protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>recombinant protein vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000483 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000483">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000483</metadata:prefixIRI>
        <obo:IAO_0000115>A subunit vaccine that is made using a part of whole organism as subunit for vaccine development. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000484 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000484">
        <owl:equivalentClass>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000484</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that uses a modified virus or bacterium as the vector to deliver vaccine antigen(s) to the cells of the host body.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant vector vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000485 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000485</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17145948</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=128</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010965"/>
        <obo:VO_0001818>128</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli subunit vaccine using CO393</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000486 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000486">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000912"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000486</metadata:prefixIRI>
        <obo:IAO_0000115>A chicken egg protein allergen where the protein allergen is ovalbumin, the main protein found in egg write, making up 60-65% of the total protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Ovalbumin</obo:IAO_0000119>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>chicken ovalbumin egg protein allergen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000487 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000487">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010451"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000487</metadata:prefixIRI>
        <obo:IAO_0000115>a S. typhi vaccine that is live and orally administerred</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0005438>25</obo:VO_0005438>
        <obo:VO_0010151>40213242</obo:VO_0010151>
        <obo:VO_1000000>typhoid vaccine, live, oral</obo:VO_1000000>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>typhoid live oral vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000488 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000488">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000488</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:14688094</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:17258324</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=126</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>126</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli subunit vaccine using FyuA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000489 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000489">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000489</metadata:prefixIRI>
        <obo:IAO_0000115>A licensed vaccine role that is bears in a licensed human vaccine.</obo:IAO_0000115>
        <obo:IAO_0000116>Discussed among Barry Smith, Anna Maria Masci, Jie Zheng and Oliver He. The vaccine recipient will be associate with vaccine directly rather than using the role.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
        <rdfs:label>obsolete licensed human vaccine role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000490 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000490">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000490</metadata:prefixIRI>
        <obo:IAO_0000115>Process that results in an adaptive immune response to one or more antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Immunization</obo:IAO_0000119>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>immunization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000491 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000491">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000490"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000491</metadata:prefixIRI>
        <obo:IAO_0000115>An immunization that involves the introduction of foreign molecules into a recipient body, in a way which causes the recipient to actively induce adaptive immunity against the immunization target.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Immunization</obo:IAO_0000119>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>active immunization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000492 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000492">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000490"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000585"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000492</metadata:prefixIRI>
        <obo:IAO_0000115>An immunization where pre-synthesized elements of the immune system are transferred to an organism so that the body does not need to produce these elements itself.</obo:IAO_0000115>
        <obo:IAO_0000116>Currently, antibodies can be used for passive immunization. This method of immunization works very quickly. However, it is short lasting. The antibodies are naturally broken down. If there are no B cells to produce more antibodies, they will disappear.</obo:IAO_0000116>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Immunization</obo:IAO_0000119>
        <obo:OBI_0000417 rdf:resource="http://purl.obolibrary.org/obo/VO_0000585"/>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>passive immunization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000493 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000493">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000491"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000493</metadata:prefixIRI>
        <obo:IAO_0000115>natural active immunization is an active immunization that occur naturally when a person or animal comes in contact with antigens includeing microbes.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Immunization</obo:IAO_0000119>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>natural active immunization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000494 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000494">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000490"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001274"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000585"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000494</metadata:prefixIRI>
        <obo:IAO_0000115>Immunization that is induced by a vaccine via vaccination process.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>artificial active immunization</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Immunization</obo:IAO_0000119>
        <obo:OBI_0000293 rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <obo:OBI_0000417 rdf:resource="http://purl.obolibrary.org/obo/VO_0000585"/>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine immunization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000495 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000495">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000491"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000495</metadata:prefixIRI>
        <obo:IAO_0000115>induction of adaptive immune response to antigen is an active immunization process that results in induction of adaptive immune response to some antigens, for example, in a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>induction of adaptive immune response to antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000496 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000496">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000496</metadata:prefixIRI>
        <obo:IAO_0000115>Process that prevents a disorder that is the physical basis of a disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>disorder prevention</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000497 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000497">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000497</metadata:prefixIRI>
        <obo:IAO_0000115>Process that leads to treat a disorder that is the physical basis of a disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>disorder treatment</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000498 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000498">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000491"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000498</metadata:prefixIRI>
        <obo:IAO_0000115>modification of adaptive immune response to antigen is an active immunization process that results in modification of an adaptive immune response to some antigens, for example, in a therapeutic vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>modification of adaptive immune response to antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000499 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000499">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000499</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete preventive infectious disease vaccine function</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000500 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000500">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000496"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000500</metadata:prefixIRI>
        <obo:IAO_0000115>infection disorder prevention is a process that prevents a disorder that is the physical basis of an infectious disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>infection disorder prevention</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000501 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000501">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000963"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000501</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17145948</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=281</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001818>281</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli vaccine using verocytotoxin toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000502 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000502">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000974"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000502</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Inactivated ETEC expressing CFA/I and CFA/II</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:1612730</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=286</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>286</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Inactivated ETEC expressing CFA/I and CFA/II vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000503 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000503">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001476"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001476"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000503</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed sheep vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000504 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000504">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000504</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine role that indicates the vaccine being a whole organism vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>whole organism vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000505 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000505">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000505</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:1612730</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=278</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>278</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>EHEC O157 subunit vaccine using his-tagged N-terminal intimin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000506 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000506">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000617"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000617"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000506</metadata:prefixIRI>
        <obo:IAO_0000115>an organism that is used as part of a vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000617"/>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>vaccine organism</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000507 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000507">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000507</metadata:prefixIRI>
        <obo:IAO_0000115>A Canada  licensed vaccine role that indicates the vaccine is for veterinary uses.</obo:IAO_0000115>
        <obo:IAO_0000116>Discussed among Barry Smith, Anna Maria Masci, Jie Zheng and Oliver He. The vaccine recipient will be associate with vaccine directly rather than using the role.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
        <rdfs:label>obsolete Canada licensed veterinary vaccine role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000508 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000508">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000735"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000508</metadata:prefixIRI>
        <obo:IAO_0000115>a diphtheria vaccine that uses diphtheria toxoid</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Diphtheria toxoid vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000509 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000509">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10114"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000509</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>nontypeable H. influenzae P5 peptide MVF/H3 vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10603411</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=193</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001818>193</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10114"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae P5 peptide MVF/H3 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000510 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000510">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10114"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000510</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>nontypeable H. influenzae rTbpB vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10225866</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=195</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001818>195</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10114"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae rTbpB vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000511 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000511">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000619"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000511</metadata:prefixIRI>
        <obo:IAO_0000115>ACAM2007 is a vaccine candidate expressing CFA/II.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=115</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095642/</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>115</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ETEC vaccine ACAM2007</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000512 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000512">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10240"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10240"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000512</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine against a disease caused by a virus belong to Poxviridae. </obo:IAO_0000115>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10240"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000513 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000513">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_400570"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000512"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_400570"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000513</metadata:prefixIRI>
        <obo:IAO_0000115>a Pox vaccine for Quail pox</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_400570"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Quail pox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000514 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000514">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000514</metadata:prefixIRI>
        <obo:IAO_0000115>a Salmonella vaccine against both typhoid caused by S. typhi and paratyphoid caused by S. paratyphi.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>typhoid-paratyphoid vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000515 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000515">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000549"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000515</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>rough phenotype</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000516 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000516">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000516</metadata:prefixIRI>
        <obo:IAO_0000115>a protein from human</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>human protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000517 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000517">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000619"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010941"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000517</metadata:prefixIRI>
        <obo:IAO_0000115>ACAM2017 was derived from ACAM2007. Genes aroC, ompC, and ompF were deleted, while CS1 and pStrep were added.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17566016</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=117</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095642/</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/VO_0010941"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>117</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ETEC vaccine ACAM2017</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000518 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000518">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010872"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000518</metadata:prefixIRI>
        <obo:IAO_0000115>DNA vaccine contains the gene fragment encoding AAs 173-764 of PA.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. anthracis DNA vaccine encoding PA63</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:9987172</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=23</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010872"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>23</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis DNA vaccine encoding PA63</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000519 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000519">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000516"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000519</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>human ACPP</rdfs:label>
        <rdfs:seeAlso>GenBank: AC020633; Protein RefSeq: NP_001090</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000521 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000521">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010857"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000521</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. anthracis DNA vaccine encoding PA83 and LF</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15342913</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=30</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010857"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>30</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis DNA vaccine encoding PA83 and LF</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000522 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000522">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010872"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000522</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>DAAV using PA and PGA</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:12960361</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=24</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010872"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>24</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DAAV using PA and PGA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000523 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000523">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000549"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000523</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>smooth phenotype</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000526 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000526">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000526</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>rPA with adjuvant Nanoemulsion</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17502384</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=309</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>309</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rPA with adjuvant nanoemulsion vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000528 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000528">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000528</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>M. tuberculosis arabinomannan-protein conjugate</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:12922145</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=223</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>223</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis arabinomannan-protein conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000532 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000532">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000532</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that is loacted in the hypodermis (subcutaneous tissue) region. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>subcutaneous route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000533 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000533">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000811"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000533</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>subdominant epitope in vaccine</obo:IAO_0000118>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>vaccine subdominant epitope</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000534 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000534">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000534</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is composed of a purified protein(s) or other antigenic determinant(s) from a disease-causing organism. A subunit vaccine does not include the whole organism of a pathogen, so the subunits have less risk of causing adverse reactions.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000535 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000535">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010919"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000535</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>recombinant S. typhimurium secreting M. tuberculosis ESAT-6</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11427279</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=176</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010919"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>176</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant Salmonella typhimurium secreting Mycobacterium tuberculosis ESAT-6 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000536 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000536">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010919"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000536</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Ag85B and ESAT-6 fusion protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=171</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010919"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>171</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ag85B and ESAT-6 fusion protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000539 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000539">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000541"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002422"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000539</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>equine EEV, VEV and WEV encephalomyelitis-influenza vaccine-tetanus toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000540 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000540">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000540</metadata:prefixIRI>
        <obo:IAO_0000115>time of survival of live vaccine inside host is a temporal interval during which a live vaccine survives inside a host organism. This entity is related to the process survival of live vaccine inside host.</obo:IAO_0000115>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>temporal region</oboInOwl:inSubset>
        <rdfs:label>time of survival of live vaccine inside host</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000541 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000541">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0002420"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000541</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>equine EEV, VEE &amp; WEV encephalomyelitis-tetanus toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000542 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000542">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000541"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002428"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000542</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>equine EEV, VEV and WEV encephalomyelitis-rhinopneumonitis-influenza vaccine-tetanus toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000543 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000543">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010951"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000543</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>attenuated M. bovis strain WAg539</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15784584</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=177</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010951"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>177</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>attenuated Mycobacterium bovis strain WAg539 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000544 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000544">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001374"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000544"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000544</metadata:prefixIRI>
        <metadata:treeView rdf:resource="http://purl.obolibrary.org/obo/VO_0000544"/>
        <obo1:part_of rdf:resource="http://purl.obolibrary.org/obo/VO_0000544"/>
        <obo:IAO_0000115>a vaccinee that is a human being</obo:IAO_0000115>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>human vaccinee</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000545 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000545">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000546"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002351"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000544"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000545</metadata:prefixIRI>
        <obo:IAO_0000115>a population of human beings who are vaccinated.</obo:IAO_0000115>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/630</obo:IAO_0000233>
        <obo:RO_0002351 rdf:resource="http://purl.obolibrary.org/obo/VO_0000544"/>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>human vaccinee population</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000546 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000546">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002351"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001374"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000546</metadata:prefixIRI>
        <obo:IAO_0000115>a population group that are vaccinated with a specific vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccinee group</obo:IAO_0000118>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/630</obo:IAO_0000233>
        <obo:RO_0002351 rdf:resource="http://purl.obolibrary.org/obo/VO_0001374"/>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>vaccinee population</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000548 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000548">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000545"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002351"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000548</metadata:prefixIRI>
        <obo:RO_0002351 rdf:resource="http://purl.obolibrary.org/obo/VO_0000554"/>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>human vaccinee population at age 2-17 years old</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000549 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000549">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000549</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>bacterial phenotype</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000550 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000550">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000550</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is used for treatment for a disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>therapeutic vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000551 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000551">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000551</metadata:prefixIRI>
        <obo:IAO_0000115>A licensed vaccine role that is bears in a licensed veterinary vaccine.</obo:IAO_0000115>
        <obo:IAO_0000116>Discussed among Barry Smith, Anna Maria Masci, Jie Zheng and Oliver He. The vaccine recipient will be associate with vaccine directly rather than using the role.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
        <rdfs:label>obsolete licensed veterinary vaccine role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000552 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000552">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000552</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>attenuated M. bovis strain WAg520</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10225931</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=179</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>179</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>attenuated Mycobacterium bovis strain WAg520 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000554 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000554">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000544"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000554"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000554</metadata:prefixIRI>
        <metadata:treeView rdf:resource="http://purl.obolibrary.org/obo/VO_0000554"/>
        <obo1:part_of rdf:resource="http://purl.obolibrary.org/obo/VO_0000554"/>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>human vaccinee at age 2-17 years old</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000555 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000555">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000555</metadata:prefixIRI>
        <obo:IAO_0000115>A titer (or titre) is a measure of concentration. Titer testing employs serial dilution to obtain approximate quantitative information from an analytical procedure that inherently only evaluates as positive or negative. The titer corresponds to the highest dilution factor that still yields a positive reading; for example, positive readings in the first 8 serial twofold dilutions translate into a titer of 1:256.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB:http://en.wikipedia.org/wiki/Titer</obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>titer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000556 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000556">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010394"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000556</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine that is designed to immunize against two or more strains of the same microorganism, or against two or more microorganisms.</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://coastalcarolinaresearch.com/?p=679</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010394"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>multivalent vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000557 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000557">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000557</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>attenuated M. bovis strain WAg522</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10225931</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=180</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>180</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>attenuated Mycobacterium bovis strain WAg522 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000558 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000558">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010915"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000558</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>recombinant nontypeable H. influenzae protein P6 with AdDP</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15031801</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=189</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010915"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001818>189</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant nontypeable Haemophilus influenzae protein P6 vaccine with AdDP adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000559 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000559">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000559</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant, adamantylamide dipeptide (AdDP) is the desmuramyl analog of MDP.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>AdDP</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:8375945</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>adamantylamide dipeptide vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000560 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000560">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23367"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000560</metadata:prefixIRI>
        <obo:IAO_0000115>A toxin is a poisonous substance produced within living cells or organisms; man-made substances created by artificial processes are thus excluded. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:comment>The term was first used by organic chemist Ludwig Brieger (1849-1919).[3]
For a toxic substance not produced within living organisms, &quot;toxicant&quot; and &quot;toxics&quot; are also sometimes used.[citation needed].
Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their severity, ranging from usually minor and acute (as in a bee sting) to almost immediately deadly (as in botulinum toxin).-- from Wikipedia.
</rdfs:comment>
        <rdfs:label>toxin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000561 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000561">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000561</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine containing a toxoid, used to protect against toxins produced by certain bacteria. A toxoid (also called inactivated toxin) is a processed toxin that has been treated by chemical means, heat, or irradiation and is no longer capable of causing disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>toxoid vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000562 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000562">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000278"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000562</metadata:prefixIRI>
        <obo:BFO_0000054 rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <obo:BFO_0000054 rdf:resource="http://purl.obolibrary.org/obo/VO_0000497"/>
        <obo:IAO_0000115>A vaccine function realized the process of vaccination and leading to induction of an adaptive immune response to treat an existing specific disorder.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>therapeutic vaccine function</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000563 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000563">
        <owl:equivalentClass>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
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                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000641"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000137"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000563</metadata:prefixIRI>
        <obo:IAO_0000115>a combination vaccine that is used against both bacterial and viral infections.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000137"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bacterial and viral combination vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000564 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000564">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010950"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000564</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>M. tuberculosis secA2 mutant</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17671656</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=222</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/VO_0010950"/>
        <obo:VO_0001818>222</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Guerin vaccination</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis secA2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000565 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000565">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010936"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000565</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>rBCG-Ag85A[Tokyo]</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17720625</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=236</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010936"/>
        <obo:VO_0001818>236</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rBCG-Ag85A[Tokyo] vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000566 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000566">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_662"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_662"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000566</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Vibrio infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Vibrio</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_662"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vibrio vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000567 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000567">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000567</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16520093</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=166</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>166</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine Rv1806-1807</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000568 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000568">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                    <owl:Restriction>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_194"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000568</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Campylobacter bacterial infectioni.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_194"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000569 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000569">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000286"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000569</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced up-regulated gene expression</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000571 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000571">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000571</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses an AAV virus as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>Adeno-associated virus vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 24702846; PMID: 24568220; PMID: 24660751; PMID: 24849042; PMID: 24742767; PMID: 24827459</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>AAV vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 272636</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000572 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000572">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000272"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000572</metadata:prefixIRI>
        <obo:IAO_0000115>vaccination protocol is the protocol of a vaccination procedure.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccination schedule</obo:IAO_0000118>
        <obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccination protocol</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000573 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000573">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_810"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_810"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000573</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Chlamydia bacterial infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_810"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000574 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000574">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000574</metadata:prefixIRI>
        <obo:IAO_0000115>A path that is located in gross anatomical part of an organism (e.g., human) and is used for administering a vaccine, a drug, fluid, poison, or other substance into the body. </obo:IAO_0000115>
        <obo:IAO_0000116>CDISC has a codelist: Rout of Administration. Desription from CDISC: The course by which a substance was administered in order to reach the site of action in the body. CDISC_SDTM_Route_of_Administration_Terminology</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://en.wikipedia.org/wiki/Route_of_administration</obo:IAO_0000119>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>route of administration</rdfs:label>
        <rdfs:seeAlso>http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C38114</rdfs:seeAlso>
        <rdfs:seeAlso>http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C66729</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000575 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000575">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000441"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000575</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine candidate is a processed material that is designed to prevent or ameliorate a disorder in a target organism by modulating adaptive immune responses in that organism by administrating the vaccine.</obo:IAO_0000115>
        <obo:IAO_0000116>During our call, we decided not to say vaccine candidate is an output of vaccine preparation, which may be reserved for vaccine alone. -- Aug 4, 2009.</obo:IAO_0000116>
        <obo:IAO_0000117>Alan Ruttenburg</obo:IAO_0000117>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000441"/>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>vaccine candidate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000576 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000576">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000851"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_9546"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000576</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_9546"/>
        <obo:IAO_0000115>vaccine preservative that has thimerosal as part.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>thimerosal vaccine preservative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000577 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000577">
        <owl:equivalentClass>
            <owl:Class>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000534"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000577</metadata:prefixIRI>
        <obo:IAO_0000115>A subunit vaccine that uses small peptide(s) as immunoepitopes. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>epitope vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>peptide-based synthetic vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Peptide_vaccine</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000578 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000578">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000578</metadata:prefixIRI>
        <obo:IAO_0000115>H1N1 Influenza vaccine is an Influenza virus vaccine that is used to vaccinate against H1N1 Influenza subtype vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>H1N1 influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000579 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000579">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000661"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000579</metadata:prefixIRI>
        <obo:IAO_0000115>bacterial vaccine that is used to protect against Haemophilus somnus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus somnus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000580 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000580">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000179"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000147"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000850"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000147"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000580</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine component is a chemical substance added to a vaccine to enhance and direct the immune response to a protective antigen. Vaccine adjuvants may cause a range of serious side-effects.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Paola Roncaglia</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/809</obo:IAO_0000233>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000147"/>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000581 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000581">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000581</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>H. influenzae gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000582 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000582">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000683"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000582</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine regulatory process that is for vaccine producer to apply for vaccine license.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine license application</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000583 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000583">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000581"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000583</metadata:prefixIRI>
        <obo:IAO_0000116>Encodes for protein P4</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>nontypeable H. influenzae gene hel (encoding P4)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000584 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000584">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000584</metadata:prefixIRI>
        <obo:IAO_0000115>An assay that is used to detect the immune response of a host to vaccination of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>immune response detection assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000585 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000585">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000585</metadata:prefixIRI>
        <obo:IAO_0000115>immunization objective is the specification of an objective to achieve immunization.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Immunization</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>immunization objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000586 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000586">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000556"/>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000556"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000586</metadata:prefixIRI>
        <obo:IAO_0000115>a multivalent vaccine that is designed to immunize against at least one bacterial disease and one viral disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>multivalent vaccine against bacterial and viral diseases</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000587 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000587">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_517"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003532"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_517"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000587</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine against infection of Bordetella bacterial infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Bordetella</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_517"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000588 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000588">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000588</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>M. tuberculosis phoP mutant SO2</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16564606</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:17084814</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=178</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>178</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Study evaluated immunogenicity and protection against Mycobacterium tuberculosis in rhesus monkeys with an attenuated M. tuberculosis with a disrupted phoP gene (SO2) as a single-dose vaccine. SO2 treatment showed reduced average lung bacterial counts (1.0 and 1.2 log respectively, compared with 0.4 log for BCG) and significant protective effect by reduction in C-reactive protein levels, body weight loss, and decrease of erythrocyte-associated hematologic parameters (MCV, MCH, Hb, Ht) as markers of inflammatory infection, all relative to non-vaccinated controls</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis phoP mutant SO2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000589 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000589">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_642"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_642"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000589</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that is used to protect against Aeromonas bacterial infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_642"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Aeromonas vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000590 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000590">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000055"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000059"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001479"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000590</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine preparation is a manufacturing process to produce a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine generation</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine production</obo:IAO_0000118>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000591 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000591">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000712"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001209"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000591</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000712"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0001209"/>
        <obo:IAO_0000115>An assay that is used to detect if a vaccine protects a host against infection of virulent pathogen after vaccine immunization.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine challenge experiment</obo:IAO_0000118>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>vaccine protection assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000592 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000592">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1763"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1763"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000592</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Mycobacterium bacterial infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Mycobacterium</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1763"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000593 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000593">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000106"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000593</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine specific T cell cytokine production</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000594 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000594">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000106"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000594</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine specific T cell mediated cytotoxicity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000595 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000595">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000984"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000595</metadata:prefixIRI>
        <obo:IAO_0000115>A dose of vaccine specified by the vaccine manufacturer, distributor, or a regulatory agent.</obo:IAO_0000115>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine dose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000596 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000596">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000596</metadata:prefixIRI>
        <obo:IAO_0000115>Planned process by which a vaccine is tested clinically for safety and effectiveness. Clinical trials are conducted in phases. Classically, clinical trials unfold in three phases in order to gather data and information about a vaccine and its performance. This will form the basis of a dossier submitted to regulatory authorities by way of an application for licensure. After a vaccine is licensed and is being used by large numbers of people, a Phase IV study may or may not be taken for vaccine clinical evaluation.</obo:IAO_0000115>
        <obo:IAO_0000116>Most vaccines against a pathogen (e.g., HIV) are not tested by vaccinating people and then deliberately exposing them to virulent pathogen (e.g., HIV). This strategy is never for a vaccine against a disease as serious as HIV.
The best way to determine if a vaccine is effective is to test it in a randomized, controlled, double-blind clinical trial. This type of trial is often referred to as the gold standard in medical research and provides the strongest evidence for the efficacy of a vaccine.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000293 rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <obo:OBI_0000293 rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine clinical trial</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000597 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000597">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000597</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete class</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000598 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000598">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000504"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000598</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that uses whole organism as its component</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://onlinelibrary.wiley.com/doi/10.1038/npg.els.0000491/full</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000504"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>whole organism vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000599 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000599">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000179"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000145"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003674"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000145"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000599</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine vector that is a genetically engineered virus or bacterium used to deliver genetic code into the cells within the body.</obo:IAO_0000115>
        <obo:IAO_0000116>a vaccine component that uses a microbe (e.g., bacterium, virus, and parasitic organism) as a vector that is inserted with the DNA(s) of a heterologous protective antigen(s) to generate a &quot;recombinant vector vaccine&quot;. The microorganism used as a vector generally has a stable non or low pathogenic phenotype for the species the vaccine is intended for. </obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>recombinant vector</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Vaccine</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.biosafety.be/GT/Regulatory/Veterinary_vaccines/EMEA_000404en.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003856.pdf</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000145"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>recombinant vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000600 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000600">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001146"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000600</metadata:prefixIRI>
        <obo:IAO_0000115>an orthopoxvirus vaccine vector that uses vaccinia virus as the vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccinia virus vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10245</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000601 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000601">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_629"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003533"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_629"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000601</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Yersinia bacterial infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_629"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000602 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000602">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_635"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003551"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000602</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that is used to protect against Edwardsiella bacterial infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_635"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Edwardsiella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000603 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000603">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000603</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=173</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>173</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG mutant secreting listeriolysin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000604 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000604">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2093"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2093"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000604</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Mycoplasma bacterial infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2093"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000605 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000605">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000605</metadata:prefixIRI>
        <obo:IAO_0000115>A Canada licensed vaccine role that indicates the vaccine is used for human</obo:IAO_0000115>
        <obo:IAO_0000116>Discussed among Barry Smith, Anna Maria Masci, Jie Zheng and Oliver He. The vaccine recipient will be associate with vaccine directly rather than using the role.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
        <rdfs:label>obsolete Canada licensed human vaccine role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000606 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000606">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000606</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>delta ureC hly+ rBCG</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16110326</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=437</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>437</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>delta ureC hly+ rBCG vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000609 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000609">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005504"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000609</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that targets against a viral disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10239"/>
        <oboInOwl:hasDbXref>MeSH: D014765</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>viral vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000610 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000610">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000599"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000610</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine vector that uses a virus as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>viral vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10239</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000611 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000611">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000661"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_738"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000611</metadata:prefixIRI>
        <obo:IAO_0000115>bacterial vaccine that is used to protect against Haemophilus parasuis infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_738"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus parasuis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000612 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000612">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002146"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000612</metadata:prefixIRI>
        <obo:IAO_0000115>a virulence of vaccine that shows a virulent pheontype of the organism as the major component of a vaccine. The virulent phenotype means that an vaccine organism is virulent and is able to cause a pathogenic phenotype in a host organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccine organism virulent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000613 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000613">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001194"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000613</metadata:prefixIRI>
        <obo:IAO_0000112>M&apos; (intended to refer to a male biological sex), &apos;Male&apos;, &apos;Man&apos;, &apos;1&apos; (intended to refer to a male biological sex)</obo:IAO_0000112>
        <obo:IAO_0000115>A biological sex datum that represents the biological sex of an animal (including human) as being male.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Paul Fabry</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>male biological sex datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000614 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000614">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10114"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000614</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Nontypeable H. influenzae protein P6 with cholera toxin</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15297063</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=188</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001818>188</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10114"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae protein P6 with cholera toxin vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000615 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000615">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000615</metadata:prefixIRI>
        <obo:IAO_0000115>Role that inheres in a prepared material entity that is designed to induce protection or treatment for a disease or infection. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000616 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000616">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000616</metadata:prefixIRI>
        <obo:IAO_0000115>Animal model of vaccine research is a role played by some organism (e.g., mouse) that is used for vaccine research.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>animal model of vaccine research</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000617 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000617">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000617</metadata:prefixIRI>
        <obo:IAO_0000115>A role that inheres in a material entity that becomes an ingredient of a vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine component role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000618 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000618">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000617"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000618</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine antigen role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000619 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000619">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000041"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000619</metadata:prefixIRI>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli live attenuated vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000620 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000620">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000620</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Pasteurella multocida infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pasteurella multocida vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000621 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000621">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000616"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000621</metadata:prefixIRI>
        <obo:IAO_0000115>Animal model of vaccine research is a role played by some organism (e.g., mouse) that is used for vaccine research in the laboratory.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>laboratory animal model of vaccine research</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000622 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000622">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000618"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000622</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine antigen role that inheres in a vaccine antigen which is capable of inducing protective immunity. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine protective antigen role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000623 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000623">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000623</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine role that indicates the vaccine being a DNA vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000624 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000624">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000624</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine role that indicates the vaccine being a subunit vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>subunit vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000625 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000625">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000625</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine role that indicates the vaccine being a conjugate vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>conjugate vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000626 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000626">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000293"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000109"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000136"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000417"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000441"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000626</metadata:prefixIRI>
        <obo:IAO_0000115>Survival assessment is an assay that measures the occurence of death events in one or more organisms that are monitored over time.</obo:IAO_0000115>
        <obo:IAO_0000116>Need to point out more specifically that survival/death is measured.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000293 rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <obo:OBI_0000417 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000441"/>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>survival assessment</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000627 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000627">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001255"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010437"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000627</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine used to prevent infection by Haemophilus influenzae type b (Hib) bacteria. The vaccine works by causing your body to produce its own protection (antibodies) against the disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>H. influenzae Type b capsular polysaccharide vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>Hib polysaccharide vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:335348</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:6387614</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=165</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.mayoclinic.org/drugs-supplements/haemophilus-b-polysaccharide-vaccine-intramuscular-route-injection-route/description/drg-20064142</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>165</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae type b capsular polysaccharide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000628 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000628">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000628</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli vaccine that uses subunit antigen type.</obo:IAO_0000115>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000629 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000629</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. anthracis recombinant vaccine using PA domain 4</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11854261</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:15935874</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=20</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>20</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis recombinant vaccine using PA domain 4</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000630 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000630">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000630</metadata:prefixIRI>
        <obo:IAO_0000115>A licensed vaccine role is a regulation-assigned role that indicates that a vaccine obtains official approval for commercial production and selling on the market.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>licensed vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000631 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000631</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine in clinical trial role is a regulation-assigned role that inheres in a vaccine that is currently in clinical trial.</obo:IAO_0000115>
        <obo:IAO_0000116>In medical research, clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine in clinical trial role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000632 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000632">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000135"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000632</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine induced immue response mediated hrough a body fluid</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine-induced antibody mediated immune response</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced humoral immune response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000633 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000633">
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000633</metadata:prefixIRI>
        <obo:IAO_0000115>A B. melitensis vaccine that is recombinant B. melitensis Rev. 1 vaccine with the p39 gene deletion.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis Rev. 1 P39 deletion mutant</obo:IAO_0000118>
        <obo:IAO_0000118>B. melitensis Rev. 1 with P39 deletion</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:9784574</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=448</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>448</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis Rev. 1 with P39 deletion vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000634 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000634</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>intravenous vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000635 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000635</metadata:prefixIRI>
        <obo:IAO_0000115>a licensed vaccine with license for human use.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000636 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
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        <obo:IAO_0000115>A vaccine role that indicates the vaccine being a recombinant vector vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>recombinant vector vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000637 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000637</metadata:prefixIRI>
        <obo:IAO_0000115>bacterial vaccine that is used to protect against Flavobacterium columnare infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_996"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flavobacterium columnare vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000639 -->

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        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000639</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that protects against infection with Clostridium spp.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Clostridium</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1485"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Clostridium vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000640 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000640">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000640</metadata:prefixIRI>
        <obo:IAO_0000115>a Clostridium vaccine that protects against infection with Clostridium tetani that causes tenanus.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Tetanus toxoid vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>tetanus vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://vaccine-safety-training.org/tetanus-vaccine-example.html</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Clostridium tetani vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000641 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000641">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:minQualifiedCardinality rdf:datatype="http://www.w3.org/2001/XMLSchema#nonNegativeInteger">2</owl:minQualifiedCardinality>
                <owl:onClass rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000641</metadata:prefixIRI>
        <obo:IAO_0000115>Combination vaccine is a vaccine that induces protection against multiple infectious diseases or several different serotypes of the same organism. The anitgens contained in combination vaccines are either formulated together by the manufacturer or physically mixed by a health care provider just prior to administration. Both approaches require licensure.
Ref: Baylor NW and Midthum K. Regulation and testing of vaccines. In: Vaccines (Editors: Plotkin S, Orenstein W, and Offit P). 2008.  p1624.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>combo vaccine</obo:IAO_0000118>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/621</obo:IAO_0000233>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000137"/>
        <oboInOwl:hasDbXref>MeSH: D017778</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>combination vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000642 -->

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            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000642</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with influenza virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Influenza vaccine</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>There is no single &apos;influenza virus&apos; in NCBI_Taxon. We usually use:
(&apos;unidentified influenza virus&apos; or &apos;Influenzavirus A&apos; or &apos;Influenzavirus B&apos; or &apos;Influenzavirus C&apos;)
However, even this may not be comprehensive. </rdfs:comment>
        <rdfs:label>influenza virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000643 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000643">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001466"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000643</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine with license that is used for cattle.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed cattle vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000644 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000644">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003540"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000644</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Hepatitis B virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>hepatitis B vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Hepatitis_B_vaccine</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000645 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000645">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001462"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001462"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117565"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7898"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000645</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117565"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7898"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed fish vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000646 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000646">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003548"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000646</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Hepatitis A virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>hepatitis A vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis A virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000647 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000647">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9925"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9925"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000647</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9925"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed goat vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000648 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000648">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000601"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000648</metadata:prefixIRI>
        <obo:IAO_0000115>A bacteria vaccine that prevents against Yersinia pestis infection that causes plague.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Plague vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000649 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000649">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001467"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001467"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000649</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed dog vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000650 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000650">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003545"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000650</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Rabies virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>rabies vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000651 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000651">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003539"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000651</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Smallpox virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>smallpox vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Smallpox virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000652 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000652">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001465"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001465"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000652</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed cat vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000653 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000653">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9669"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001464"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9669"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000653</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9669"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed ferret vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000654 -->

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        <obo:IAO_0000115>A viral vaccine that protects against infection with Measles virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>measles vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Measles virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000655 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000655</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed deer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000656 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000656</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Mumps virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>mumps vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mumps virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000657 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000363"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000657</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed bird vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000658 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000658</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Rotavirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000659 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000659">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000659</metadata:prefixIRI>
        <obo:IAO_0000116>In most cases HibTITER was administered concomitantly with other vaccines including DTP, DTaP, hepatitis B vaccine, IPV, OPV, pneumococcal 7-valent conjugate vaccine, MMR, and/or meningococcal group C conjugate vaccine (not licensed in the US).</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:2057256</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9353019</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=160</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>160</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIBTITER vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000660 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000660">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000662"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000660</metadata:prefixIRI>
        <obo:IAO_0000116>Ref: http://www.rxlist.com/prohibit-drug.htm</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:2057256</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=162</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>162</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ProHIBiT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000661 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000661">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000661</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Haemophilus infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Haemophilus</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_724"/>
        <oboInOwl:hasDbXref>MeSH: D018073</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000662 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000662</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Haemophilus influenzae type b infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Haemophilus b vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>Hib vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae serotype b vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000663 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000663">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000663</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated Shigella flexneri 2a vaccine that carries deletions of the plasmid-borne virulence gene icsA (mediating intra- and intercellular spread) and the chromosomal locus iuc (encoding aerobactin).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>SC602</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10377124</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=259</obo:IAO_0000119>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>259</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SC602 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000664 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000664</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Poliovirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>polio vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Poliovirus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000665 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000665</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Japanese encephalitis virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Japanese encephalitis vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000666 -->

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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000666</metadata:prefixIRI>
        <obo:IAO_0000115>CVD 1208 is derived from wild type Shigella flexneri 2a strain 2457T and has defined deletions in four genes: (1) the guaBA chromosomal operon that encodes two enzymes (inositol 5&apos;-monophosphate dehydrogenase and guanosine 5&apos;synthase) essential for de novo purine biosynthesis; (2) set, a locus in a chromosomal pathogenicity island that encodes Shigella enterotoxin (ShET); (3) Pic, an autotransporter mucinase encoded on the opposite strand from set; and (4) sen, an invasiveness plasmid gene encoding ShET.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>CVD 1208</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15499528</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=441</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>441</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CVD 1208 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000667 -->

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        <owl:equivalentClass>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000667</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine against human papillomavirus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
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        <oboInOwl:hasDbXref>SNOMEDCT: 424519000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI: C1512511</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>human papillomavirus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000668 -->

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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000668</metadata:prefixIRI>
        <obo:IAO_0000115>CVD 1208S is the same thing as CVD 1208, but CVD 1208S was prepared using animal-free media.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>CVD 1208S</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17938573</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=272</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>272</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CVD 1208S vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000669 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000669">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003537"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000669</metadata:prefixIRI>
        <obo:IAO_0000115>a Herpesvirus vaccine that is used against Varicella-zoster virus infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Varicella vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>chickenpox and shingles virus vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella-zoster virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000670 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000670</metadata:prefixIRI>
        <obo:IAO_0000115>A Shigella flexneri vaccine that is an aro-D mutant derivative of EcSf2a-1.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>EcSf2a-2</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:1587589</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=267</obo:IAO_0000119>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>267</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>EcSf2a-2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000671 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000671">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000671</metadata:prefixIRI>
        <obo:IAO_0000115>A Salmonella vaccine against typhoid fever (or called typoid), caused by Salmonella enterica enterica, serovar Typhi. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>typhoid vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella typhi vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000672 -->

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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000672</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>heat-killed virulent Shigella flexneri 2a</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10102148</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=268</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001818>268</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>heat-killed virulent Shigella flexneri 2a vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000673 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000680"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000673</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:1937767</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=269</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>269</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella Sfl 124 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000674 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000674">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000681"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_622"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000674</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Recombinant SFL124-27 expressing S. dysenteriae type 1 O antigen</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:9169740</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=258</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>258</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_622"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant SFL124-27 expressing Shigella dysenteriae type 1 O antigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000675 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000675">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000675</metadata:prefixIRI>
        <obo:IAO_0000115>a Streptococcal vaccine that is used against S. pneumoniae infection, which causes pneumococcal diseases. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>pneumococcal vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.who.int/vaccines/en/pneumococcus.shtml</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000676 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000676">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000681"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_622"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000676</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>S. dysenteriae 1 strain WRSd1</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:12010984</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=263</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>263</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_622"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>Shigella dysenteriae 1 strain WRSd1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000677 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000677">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000680"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000677</metadata:prefixIRI>
        <obo:IAO_0000115>A  live attenuated Shigella flexneri 2a vaccine with specific deletion mutations in virG, sen, set, and guaBA.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>S. flexneri 2a strain CVD 1207</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10678904</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=260</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>260</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella flexneri 2a strain CVD 1207 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000678 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000678">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000679"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000678</metadata:prefixIRI>
        <obo:IAO_0000115>A stable attenuated Shigella sonnei strain with virG mutation. PMID:9712824.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:11895966</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9712824</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=264</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>264</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_624"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei</rdfs:comment>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>Shigella sonnei virG mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000679 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000679">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_624"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000679</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_624"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella sonnei vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000680 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000680">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000680</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella flexneri vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000681 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000681">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_622"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_622"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000681</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_622"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella dysenteriae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000682 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000682">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000680"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000682</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>S. flexneri 2a LPS vaccine complexed with N. meningitidis proteosomes</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:8500877</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=270</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>270</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella flexneri 2a LPS vaccine complexed with Neisseria meningitidis proteosomes vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000683 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000683">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000683</metadata:prefixIRI>
        <obo:IAO_0000115>Process that regulates vaccine-related processes, such as vaccine trial, vaccine license application.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine regulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000684 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000684">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000684</metadata:prefixIRI>
        <obo:IAO_0000115>Process of transporting vaccine from one place to another place.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine transportation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000685 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000685">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000685</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant vector vaccine role that inheres in a bacterium that carries a vaccine antigen for development of a particular vaccine </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete recombinant bacterial vector vaccine role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000692 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000692">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000692</metadata:prefixIRI>
        <obo:IAO_0000115>A subunit vaccine role that indicates the vaccine being a peptide vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>peptide vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000702 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000702">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000702</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant vector vaccine role that inheres in a virus that carries a vaccine antigen for development of a particular vaccine </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete recombinant viral vector vaccine role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000704 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000704">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000854"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000704</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine residual that is from antibiotics used during the manufacture process.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>antibiotics vaccine residual</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000705 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000705">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000584"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000705</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>vaccine specific antibody test</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000706 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000706">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000683"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000706</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine regulation process for vaccine clinical trials.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine trial regulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000707 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000707">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000707</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccination process that occurs at the first time to a host organization in a specified period.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>prime vaccination</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>primary vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000708 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000708">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000062"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000707"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000708</metadata:prefixIRI>
        <obo:BFO_0000062 rdf:resource="http://purl.obolibrary.org/obo/VO_0000707"/>
        <obo:IAO_0000115>A vaccination process that occurs after the primer vaccination with a purpose to boost host immune response to vaccine antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>boost vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000709 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000709">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000025"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000709</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000710 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000710">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000647"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001135"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010963"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9925"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9935"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000710</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Brucella melitensis Rev 1</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella melitensis Rev. 1B. melitensis strain Rev. 1</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:13416171</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=110</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/VO_0010963"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9925"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9935"/>
        <obo:VO_0001818>110</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis strain Rev. 1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000712 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000712">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000609"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000315"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000712</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine that is inactivated</obo:IAO_0000115>
        <obo:IAO_0000118>killed viral vaccine</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated viral vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000713 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000713">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000713</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>vaccine allergen disposition</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000714 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000714">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000714</metadata:prefixIRI>
        <obo:IAO_0000115>a licensed human vaccine that is licensed in Canada</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canada licensed human vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000715 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000715">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000715</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a DNA vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000716 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000716">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000716</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a conjugate vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>conjugate vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000717 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000717">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000717</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a subunit vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>subunit vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000718 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000718">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000718</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a live attenuated vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>live attenuated vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000719 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000719">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000719</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a RNA vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>RNA vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000720 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000720">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000720</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus strain RB51SOD</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella abortus strain RB51SOD</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10816475</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=11</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0000154"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>11</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus strain RB51SOD vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000721 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000721">
        <owl:equivalentClass>
            <owl:Class>
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                    <owl:Restriction>
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                    </owl:Restriction>
                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000025"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000721</metadata:prefixIRI>
        <obo:IAO_0000115>a Brucella vaccine against infection wtih B. suis</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella suis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000722 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000722">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001136"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000722</metadata:prefixIRI>
        <obo:IAO_0000115>An orally administrable brucellosis vaccine that was was developed in China. It is effective for oral vaccination of sheep, goats, cattle and pigs.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Brucella suis S2</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella suis strain 2</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:3541425</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=447</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>447</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella suis strain 2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000723 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000723">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001476"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000723</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus strain 45/20</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella abortus strain 45/20</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:8236802</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=123</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <obo:VO_0001818>123</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus strain 45/20 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000724 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000724">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000727"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10358"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000724</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10358"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>cytomegalovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000725 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000725">
        <owl:equivalentClass>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003546"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000725</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Dengue virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Dengue vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000726 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000726">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000726</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Ebola virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Ebola vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000727 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000727">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_548681"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000727</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Herpesvirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_548681"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpesvirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000728 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000728">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000728</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine role that indicates the vaccine being a RNA vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>RNA vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000729 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000729">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000727"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3344809"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000729</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3344809"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000730 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000730">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000730</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0012162"/>
        <rdfs:label>obsolete Marek disease vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000731 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000731">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000736"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010441"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010442"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010450"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
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        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8781"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000731</metadata:prefixIRI>
        <obo:IAO_0000115>A Measles-Mumps vaccine that also protects against infection with  Rubella virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>MMR</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8781"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
        <obo:VO_0005438>03</obo:VO_0005438>
        <obo:VO_0010151>40213183</obo:VO_0010151>
        <obo:VO_1000000>measles, mumps and rubella virus vaccine</obo:VO_1000000>
        <obo:VO_1000001>MMR</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>MMR is usually live attenuated. </rdfs:comment>
        <rdfs:label>Measles-Mumps-Rubella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000732 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000732</metadata:prefixIRI>
        <obo:IAO_0000115>A Corynebacterium diphtheriae vaccine that also protect against infection with Clostridium tetani.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Diphtheria-Tetanus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000733 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000733</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>CVD 1204(pGA1-CS2)</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11292735</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=265</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>265</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CVD 1204(pGA1-CS2) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000734 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000734</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=442</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>442</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CVD 1204(pGA1-CS3) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000735 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000735</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that protects against infection with Corynebacterium diphtheriae that causes Diphtheria.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>diphtheria vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Corynebacterium diphtheriae vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000736 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000736</metadata:prefixIRI>
        <obo:IAO_0000115>A Measles virus vaccine that also protects against infection with  Mumps virus.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Measles-Mumps vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000737 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000737</metadata:prefixIRI>
        <obo:IAO_0000115>A Measles-Mumps-Rubella vaccine that also protects against Varicella.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0000738 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000739 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000740 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000741 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000742 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000743 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000744 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000744</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against, Diphtheria, Tetanus, Pertussis (whooping cough), Polio, and Haemophilus influenzae type b.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>DTaP/IPV/Hib vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.healthlinkbc.ca/healthlinkbc-files/dtap-ipv-hib-vaccine</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000745 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000745">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010438"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010439"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000745</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0005438>104</obo:VO_0005438>
        <obo:VO_0010151>40213303</obo:VO_0010151>
        <obo:VO_1000000>hepatitis A and hepatitis B vaccine</obo:VO_1000000>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human Hepatitis A &amp; B vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000746 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000746">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000644"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000644"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000662"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000746</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine against Hepatitis B virus and at the same time against bacterial H. influenzae serotype b.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus b and Hepatitis B vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000747 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000747">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010920"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000747</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that contains DNA and modified vaccinia virus Ankara (MVA) encoding thrombospondin-related adhesion protein (TRAP) with a multiple-epitope string ME (ME-TRAP). This vaccine is used with a prime-boost regime by DNA priming and MVA boosting.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>DNA and MVA encoding ME-TRAP</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16988273</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=210</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010920"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>210</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA and MVA encoding ME-TRAP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000748 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000748">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000748</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Papillomavirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/688"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0003538"/>
        <rdfs:label>obsolete Papillomavirus vaccine</rdfs:label>
        <rdfs:seeAlso>MeSH: D053918</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000749 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000749">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000749</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Parainfluenza virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>parainfluenza vaccine</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parainfluenza virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000750 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000750">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003537"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000750</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Pseudorabies virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>pseudorabies vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000751 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000751">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000751</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that prevents against infection with Simian immunodeficiency virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>SAIDS vaccine</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Simian immunodeficiency virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000752 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000752">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003546"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000752</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against West Nile virus infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>West Nile virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000753 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000753">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1273"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000753</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that prevents infection with Respiratory syncytial virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1273"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Respiratory syncytial virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000754 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000754">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000754</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is used in conjunction with diagnostic tests to differentiate vaccinated animals from carrier animals. It can be a subunit or a gene-deleted vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:hasDbXref>MeSH: D022581</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>marker vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000755 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000755">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000246"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000086"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000246"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000755</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is edible and derived from an edible plant. The transgenic plant is used as recombinant protein production system. The edible plant tissue functions as an oral vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000086 rdf:resource="http://purl.obolibrary.org/obo/VO_0000246"/>
        <oboInOwl:hasDbXref>MeSH: D022462</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>edible vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000756 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000756">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000756</metadata:prefixIRI>
        <obo:IAO_0000115>A subunit vaccine that is produced by using only the antigenic part of the disease causing organism. It often requires a &quot;booster&quot; every few years to maintain their effectiveness.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>acellular vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000757 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000757">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001356"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000757</metadata:prefixIRI>
        <obo:IAO_0000115>A particulate antigen delivery system vaccine adjuvant that consists of an assembly of antigens in multimeric form and presents an antigen to induce specific immunologic responses. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines. MeSH term: D20.215.894.860.449.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>ISCOM</obo:IAO_0000118>
        <obo:IAO_0000118>The immunostimulating complex</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>ISCOM vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000758 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000758">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5855"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5855"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000758</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5855"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium vivax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000759 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000759">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000759</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is used to prevent conception.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>antifertility vaccine</obo:IAO_0000118>
        <oboInOwl:hasDbXref>MeSH: D022642</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>contraceptive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000760 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000760">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10652"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10652"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000760</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that prevents or treats Alzheimer disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10652"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:hasDbXref>MeSH: D023582</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Alzheimer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000761 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000761">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000761</metadata:prefixIRI>
        <obo:IAO_0000115>Plasmodium vaccine is a vaccine that prevents against Plasmodium species causing malaria. It is made from antigens arising from any of the four strains of Plasmodium which cause malaria in humans, or from P. berghei which causes malaria in rodents.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Plasmodium vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>malarial Vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>malaria vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000762 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000762">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38568"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38568"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000762</metadata:prefixIRI>
        <obo:IAO_0000115>a protozoan vaccine that prevents against infection with Leishmania.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Leishmaniasis vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38568"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000763 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000763">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000566"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1498"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000763</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that prevents infection with Vibrio cholera.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>cholera vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1498"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vibrio cholerae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000764 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000764">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003518"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000764</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Borrelia burgdorferi infection causing Lyme disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Lyme disease vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <oboInOwl:hasDbXref>MeSH: D022123</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borrelia burgdorferi vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000765 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000765">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000587"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000765</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that prevents against Bordetella pertussis infection that causes pertussis or whooping cough.</obo:IAO_0000115>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Acellular Pertussis Vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>Pertussis vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000766 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000766">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_286"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_286"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000766</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Pseudomonas infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_286"/>
        <oboInOwl:hasDbXref>MeSH: D054406</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudomonas vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000767 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000767">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_780"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003550"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_780"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000767</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Rickettsia infection. Typhus is any of several similar diseases caused by Rickettsia bacteria. So Rickettsial vaccine is also called typhus vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>typhus vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Typhus_vaccine</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_780"/>
        <oboInOwl:hasDbXref>MeSH: D012290</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rickettsial vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000768 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000768">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003552"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000768</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Salmonella species infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Salmonella</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:hasDbXref>MeSH: D022562</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000769 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000769">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003552"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000769</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Shigella species infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
        <oboInOwl:hasDbXref>MeSH: D022281</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000770 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000770">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1279"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003555"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1279"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000770</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Staphylococcus infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Staph vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>Staphylococcus vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1279"/>
        <oboInOwl:hasDbXref>MeSH: D013209</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcal vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000771 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000771">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010443"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000771</metadata:prefixIRI>
        <obo:IAO_0000115>BCG Vaccine is a Mycobacterium tuberculosis vaccine that is a live attenuated strain of Mycobacterium bovis (Bacillus Calmette Guerin; BCG).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Bacillus Calmette Guerin</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=143</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/776</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>143</obo:VO_0001818>
        <obo:VO_0003160>For the prevention of tuberculosis in persons not previously infected with M. tuberculosis who are at high risk for exposure.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/78331/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>103050</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0005438>19</obo:VO_0005438>
        <obo:VO_0010151>40213271</obo:VO_0010151>
        <obo:VO_1000000>Bacillus Calmette-Guerin vaccine</obo:VO_1000000>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000772 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000772">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1301"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003555"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1301"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000772</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against streptococcal infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Streptococcus vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Streptococcus</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1301"/>
        <oboInOwl:hasDbXref>MeSH: D022541</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcal vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000773 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000773">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000773</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>MSP3-LSP with aluminium hydroxide</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17280744</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=207</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>207</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MSP3-LSP subunit vaccine with aluminium hydroxide adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000774 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000774">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011218"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000774</metadata:prefixIRI>
        <obo:IAO_0000115>RTS,S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium falciparum circumsporozoite surface antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum RTS,S/AS02A</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=200</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011218"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>200</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum RTS,S/AS02A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000775 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000775">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010958"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000775</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum MSP1 from transgenic mice with Freund&apos;s adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11752405</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=234</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010958"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>234</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum MSP1 from transgenic mice vaccine with Freund&apos;s adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000776 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000776">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010957"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000776</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. vivax PVS25 with Montanide ISA-720</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16291764</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=208</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010957"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>208</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>P. vivax PVS25 vaccine with Montanide ISA-720 adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000777 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000777">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010923"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000777</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant E. coli-expressed protein based upon the apical membrane antigen-1 (AMA-1) of the 3D7 clone formulated with the AS02A adjuvant. PMID:17442466.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum FMP1/AS02A</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17442466</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=232</obo:IAO_0000119>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010923"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>232</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum FMP1/AS02A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000778 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000778">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010926"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000778</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum ABRA protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11489167</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9400530</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=204</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010926"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>204</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum ABRA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000779 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000779">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000779</metadata:prefixIRI>
        <obo:IAO_0000115>An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus NP protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0011387"/>
        <rdfs:label>obsolete NP-VRP</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000780 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000780">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000780</metadata:prefixIRI>
        <obo:IAO_0000115>An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus GP protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>GP-VRP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=69</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>69</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>GP-VRP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000781 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000781">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010866"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000781</metadata:prefixIRI>
        <obo:IAO_0000115>An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP24 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>VRP expressing VP24</obo:IAO_0000118>
        <obo:IAO_0000118>alphavirus replicon expressing VP24</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11485406</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=65</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010866"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>65</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VRP expressing VP24 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000782 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000782">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010867"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000782</metadata:prefixIRI>
        <obo:IAO_0000115>An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP30 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>VRP expressing VP30</obo:IAO_0000118>
        <obo:IAO_0000118>alphavirus replicon expressing VP30</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11485406</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=66</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010867"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>66</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VRP expressing VP30 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000783 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000783">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010864"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000783</metadata:prefixIRI>
        <obo:IAO_0000115>An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP35 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>VRP expressing VP35</obo:IAO_0000118>
        <obo:IAO_0000118>alphavirus replicon expressing VP35</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11485406</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=67</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010864"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>67</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VRP expressing VP35 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000784 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000784">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010868"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000784</metadata:prefixIRI>
        <obo:IAO_0000115>An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP40 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>VRP expressing VP40</obo:IAO_0000118>
        <obo:IAO_0000118>alphavirus replicon expressing VP40</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11485406</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=68</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010868"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>68</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VRP expressing VP40 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000785 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000785">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010858"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000785</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine that encodes for a secreted form of Ebola virus GP protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:9427604</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=73</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010858"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>73</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine expressing sGP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000786 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000786">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010949"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000786</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine combination that includes a DNA vaccine and a recombinant adenovirus Ad5 expressing the same codon-optimized SIV gag gene. The DNA vaccine is used for priming, and the Ad5 vaccine is used for boosting. PMID:11797011.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>DNA and adenoviral vector Ad5 expressing SIV gag protein</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11797011</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=145</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010949"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
        <obo:VO_0001818>145</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA and adenoviral vector Ad5 expressing SIV gag protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000787 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000787">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000787</metadata:prefixIRI>
        <obo:IAO_0000116>A gene that is a pathogen gene used for vaccine preparation or a host gene encoding for an immune factor important in induction of protective immunity.
a vaccine-associated gene that exists in a pathogen and has been engineered for vaccine develoment. This gene can encode for protective antigen that is overexpressed for vaccine development. This gene can also be a virulence factor that is mutated to attenuate a virulent pathogen with the purpose of making attenuated vaccine.</obo:IAO_0000116>
        <obo:IAO_0000116>The term &apos;gene&apos; has appears in several ontologies, such as Sequence Ontology (SO) and Protein Ontology (PRO). We may choose to use a &apos;gene&apos; term from other ontologies. The &apos;gene&apos; term in SO has ID: SO:0000704.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>obsolete gene</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000788 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000788">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010949"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000788</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant adenovirus (Ad5) expressing the codon-optimized SIV gag gene. PMID:11797011.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>adenoviral vector Ad5 expressing SIV gag protein</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11797011</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=444</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010949"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
        <obo:VO_0001818>444</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>adenoviral vector Ad5 expressing SIV gag protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000789 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000789">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010937"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000789</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine combination that includes a DNA vaccine and a replication-defective chimeric Ad5 vector with the Ad35 fiber (Ad5/35) that express the same codon-optimized SIV gag gene. The DNA vaccine is used for priming, and the Ad5/35 vaccine is used for boosting. PMID:16079886.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>DNA and Ad5/35 vector expressing HIV gp160 protein</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16079886</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=146</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010937"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>146</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA and Ad5/35 vector expressing HIV gp160 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000790 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000790">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000790</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Brucella gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000791 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000791">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_0000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000791</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>human gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000792 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000792">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_0000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000792</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>mouse gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000793 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000793">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000790"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000793</metadata:prefixIRI>
        <obo:IAO_0000115>A Brucella gene that is from B. abortus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000794 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000794">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000793"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_359391"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000794</metadata:prefixIRI>
        <obo:IAO_0000115>A Brucella abortus gene that has the name wboA and comes from strain 2308. </obo:IAO_0000115>
        <obo:IAO_0000116>Brucella abortus gene wboA is interrupted in Brucella abortus cattle vaccine RB51.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_359391"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>wboA from B. abortus strain 2308</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000795 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000795">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000792"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000795</metadata:prefixIRI>
        <obo:IAO_0000116>Interferon-gamma (IFN-g) is an indicative of Th1 immune response. It is produced in host immunized by vaccines such as Brucella abortus cattle vaccine RB51.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>mouse Ifng</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000796 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000796">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000791"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000796</metadata:prefixIRI>
        <obo:IAO_0000116>Interferon-gamma (IFN-g) is an indicative of Th1 immune response.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>human ifng</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000797 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000797">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_0000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000797</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>cattle gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000798 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000798">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000797"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000798</metadata:prefixIRI>
        <obo:IAO_0000116>Interferon-gamma (IFN-g) is an indicative of Th1 immune response. It is produced in host immunized by vaccines such as Brucella abortus cattle vaccine RB51.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Ifng from cattle</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000800 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000800">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0302893"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000800</metadata:prefixIRI>
        <obo:IAO_0000115>a storage process that is specifically for vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine storage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000801 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000801">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000800"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000801</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine storage that is execuated at room temperature. Room temperature is also referred to as ambient temperature. Room temperature denotes a certain temperature within enclosed space at which humans are accustomed. Room temperature is usually indicated by general human comfort, with the common range of 10 degree C (50 degree F) to 28 degree C (82.4 degree F).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine storage at room temperature</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000802 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000802">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000800"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000802</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine storage that is executed in refrigerator, usually 0-10^C.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine storage in refrigerator</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000803 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000803">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000800"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000803</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine storage that is executed in freezer under 0^C.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine storage in freezer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000804 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000804">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001018"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000804</metadata:prefixIRI>
        <obo:IAO_0000115>Effectiveness is physical quality that represents the capability of a single physical entity (e.g., vaccine) producing an effect (e.g, protection against a disease).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>effectiveness</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000805 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000805">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000804"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000805</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>effective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000806 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000806">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000804"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000806</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>ineffective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000807 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000807">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000807</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine role that indicates the vaccine being a toxoid vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>toxoid vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000808 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000808">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000808</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccination process that is implemented fast.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine rapid implementation</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>rapid vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000809 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000809">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000809</metadata:prefixIRI>
        <obo:IAO_0000115>A measure datum that measures the coverage of vaccination in a specific area during a specific time period.</obo:IAO_0000115>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>immunization coverage</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.sanofipasteur.com/sanofi-pasteur2/front/index.jsp?siteCode=SP_CORP&amp;codeRubrique=19</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.who.int/immunization_monitoring/routine/immunization_coverage/en/</obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccination coverage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000810 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000810">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000810</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pSCAR . CMV promotor is used.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSCAR DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 18022294; PMID: 19712769.</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000811 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000811">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110034"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000811</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>vaccine epitope</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000812 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000812">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000812</metadata:prefixIRI>
        <obo:IAO_0000115>a licensed vaccine role that indicates the vaccine occurs in USA.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>USA licensed vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000813 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000813">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000643"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000813</metadata:prefixIRI>
        <obo:IAO_0000115>A cattle vaccine with license that is used in USA.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>USA licensed cattle vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000814 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000814">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000984"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000814</metadata:prefixIRI>
        <obo:IAO_0000115>A dose of vaccine that is used in a vaccination. Vaccination dose may be and may be not the same as the vaccine dose.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccination dose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000815 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000815">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000044"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000815</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>monthly</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000816 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000816">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000044"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000816</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>biweekly</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000817 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000817">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000817</metadata:prefixIRI>
        <obo:IAO_0000115>A HIV vaccine that is composed of a DNA vaccine expressing conserved, multiple HIV epitopes. PMID:16359234.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16359234</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=149</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>149</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine expressing multiple HIV epitopes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000819 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000819">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000819</metadata:prefixIRI>
        <obo:IAO_0000115>A HIV vaccine that is made of recombinant HIV gp120 protein adjuvanted with the adjuvant NanoEmulsion. PMID:18260780.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>recombinant HIV gp120 with adjuvant NanoEmulsion</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:18260780</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=310</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>310</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant HIV gp120 with adjuvant NanoEmulsion vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000820 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000820">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000589"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000820</metadata:prefixIRI>
        <obo:IAO_0000115>Aeromonas bacterial vaccine that is used to protect against Aeromonas salmonicida infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Aeromonas salmonicida vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000822 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000822">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
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        </rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000822</metadata:prefixIRI>
        <obo:IAO_0000115>A cocktail vaccine of V3014-packaged VRPs expressing the SIVsm H-4i nonmyristylated matrix-capsid region, full-length gp160, and a secreted form of gp160 (gp140). PMID:12120997.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Gag-VRPs</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10462249</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12120997</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=156</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>156</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9479"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Gag-VRPs vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000823 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000823">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000823</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine against V. anguillarum infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_55601"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vibrio anguillarum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000824 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000824">
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        </rdfs:subClassOf>
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        <obo:IAO_0000115>A recombinant modified vaccinia Ankara (MVA) expressing HIV Gag, Pol, and Env proteins. PMID:16472543.</obo:IAO_0000115>
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        <obo:IAO_0000118>MVA expressing HIV Gag, Pol and Env proteins</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVA expressing HIV Gag, Pol and Env proteins vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000825 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000825</metadata:prefixIRI>
        <obo:IAO_0000115>A SIV vaccine that is composed of a DNA vaccine and a poxvirus vector expressing the same SIV antigens. PMID:15258286.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15258286</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=154</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>154</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA and poxvirus priming-boosting SIV vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000826 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000826</metadata:prefixIRI>
        <obo:IAO_0000115>A B. abortus vaccine that is recombinant B. abortus strain 19 vaccine with the p39 gene deletion.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus S19 P39 deletion mutant</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella abortus S19 with P39 deletion</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:9784574</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=449</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>449</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus S19 with P39 deletion vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000827 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000827">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000827</metadata:prefixIRI>
        <obo:IAO_0000115>A Yersinia pestis vaccine that uses a recombinant Ad5-based vector (E1a, partial E1b, and partial E3 deletion) to express Y. pestis V antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>AdsecV</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17041851</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=48</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>48</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AdsecV vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000828 -->

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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000828</metadata:prefixIRI>
        <obo:IAO_0000115>A Yersinia pestis vaccine that is a pigmentation negative mutant of Y. pestis derived from a fully virulent strain.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Yersinia EV-76</obo:IAO_0000118>
        <obo:IAO_0000118>Yersinia EV76</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia EV76 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000829 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000829">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000829</metadata:prefixIRI>
        <obo:IAO_0000115>A Yersinia pestis subunit vaccine that uses Y. pestis F1 protein as antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0001818>36</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis F1 protein vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000830 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000830</metadata:prefixIRI>
        <obo:IAO_0000115>A Y. pestis subunit vaccine that uses recombinant F1 and V antigens. PMID:312163.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rF1 + rV vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000831 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000831</metadata:prefixIRI>
        <obo:IAO_0000115>A Y. pestis subunit vaccine that uses recombinant Y. pestis V antigen. PMID:7622205.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant Yersinia pestis V antigen vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000832 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000832</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>modified Y. pestis with TLR4-stimulating LPS</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16980981</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=35</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>35</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>modified Yersinia pestis with TLR4-stimulating LPS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000833 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000833">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000833</metadata:prefixIRI>
        <obo:IAO_0000115>A Yersinia pestis subunit vaccine that contains staphylococcal protein A-V antigen fusion peptide (PAV). PMID:7622225.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Yersinia PAV</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7622225</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=62</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>62</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia PAV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000834 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000834">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010878"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000834</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>recombinant Y. pestis YopD protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10024607</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:8890210</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=37</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010878"/>
        <obo:VO_0001818>37</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant Yersinia pestis YopD protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000835 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000835">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000935"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_42890"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000835</metadata:prefixIRI>
        <obo:IAO_0000116>In vitro-cultured merozoites, chemically inactivated</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=433</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>433</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_42890"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Epm vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000836 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000836">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000836</metadata:prefixIRI>
        <obo:IAO_0000115>A Y. pestis subunit vaccine that uses Y. pestis YscF protein as antigen. PMID:15978133.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Y. pestis YscF subunit vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15978133</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=81</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010913"/>
        <obo:VO_0001818>81</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis YscF subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000837 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000837">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000837</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16546306</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=56</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>56</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>microencapsulated Caf1 and LcrV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000838 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000838">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000503"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001085"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000838</metadata:prefixIRI>
        <obo:IAO_0000116>Live temperature-sensitive mutant strain for subcutaneous or intramuscular injection</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Ovilis Enzovax</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=417</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <obo:VO_0001818>417</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ovilis Enzovax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000839 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000839">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000461"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003143"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000839</metadata:prefixIRI>
        <obo:IAO_0000116>Fowlpox virus-vectored H5</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Trovac AI H5</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=402</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>402</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trovac AI H5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000840 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000840">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000840</metadata:prefixIRI>
        <obo:IAO_0000115>A Y. pestis vaccine that uses the recombinant V10 (rV10), a variant (lacking residues 271 to 300) of Yersinia pestis LcrV. PMID:16861680.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=54</obo:IAO_0000119>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>54</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant Yersinia rV10 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000842 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000842</metadata:prefixIRI>
        <obo:IAO_0000116>Killed oral vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AquaVac ERM vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000843 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000843</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline leukemia virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000844 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000844</metadata:prefixIRI>
        <obo:IAO_0000116>Live temperature-sensitive mutant strain; spray inhalation or drinking water</obo:IAO_0000116>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_521"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Art Vax vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000845 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0001818>47</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VSV vector expressing Yersinia pestis lcrV vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000847 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000847</metadata:prefixIRI>
        <obo:IAO_0000115>A formalin-inactivated preparation that was manufactured by Cutter Biologicals (a division of Miles Laboratories, Inc.). It is now available only from Greer Laboratories, Inc. The killed or inactivated plague vaccine is prepared from Y. pestis organisms grown in artificial media and then inactivated in formaldehyde.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=31</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plague vaccine USP</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000849 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000849</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that stimulates the pig&apos;s own immune system to produce specific antibodies against GnRF. This temporarily inhibits testes function and thus stops the production and accumulation of boar taint-causing compounds.</obo:IAO_0000115>
        <obo:IAO_0000116>Peptide-protein conjugate and water-miscible adjuvant; control of boar taint</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>WEB: http://www.improvac.co.nz/sites/improvac/en-nz/Pages/productoverview.aspx</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Improvac vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000850 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
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        <obo:IAO_0000115>Vaccine component that is added to the immunogen by the vaccine manufacturer for a specific purpose. Additives include adjuvants, preservatives and stablizers, as well as materials that are added to affect pH and isotonicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine additive</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000851 -->

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        <obo:IAO_0000115>Vaccine additive that is added to a vaccine formulation to prevent the growth of bacteria or fungi that inadvertently may be introduced into the vaccine during use.
Ref: Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 73.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine preservative</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000852 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000852</metadata:prefixIRI>
        <obo:IAO_0000116>Killed vaccine against periodontitis</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Periovac</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=412</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0001818>412</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_111105"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Periovac vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000853 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000853">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000179"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000850"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000853</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine additive that helps to protect the vaccine from adverse conditions such as the freeze-drying process (for those vaccines that are freeze-dried) or heat.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 75.</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000854 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000854">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000854</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine component that remains from the vaccine manufacturing process.</obo:IAO_0000115>
        <obo:IAO_0000116>Although no all manufacturing residuals may be identified and quantified, their presence and quantity is assumed to be constant because of the constancy of the manufacturing process.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 73.</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine residual</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000855 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000855">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000854"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000855</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine residual that is used to inactivate bacteria and viruses or to detoxify bacterial toxins. For example, formaldehyde is a frequently used inactivation agent in vaccine preparation.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 78.</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>inactivation residual in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000856 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000856">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000854"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000856</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine residual that is generatead from cell culture for vaccine preparation. Examples include: antibiotics, sensitizing substances, bacterial and cellular residuals, and adventitious agents.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 78-81.</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>cell culture residual in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000857 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000857">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000133"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000287"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPMI_0000446"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000857</metadata:prefixIRI>
        <obo:IAO_0000115>Measurement process profile determined by the measurement data generated from a measurement process which indicates the degree of immunological protection in the vaccine recipient.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>CoP</obo:IAO_0000118>
        <obo:IAO_0000118>correlate of protection</obo:IAO_0000118>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>correlated profile of immune protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000858 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000858">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000857"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000858</metadata:prefixIRI>
        <obo:IAO_0000115>Correlated profile of immune protection that is reflected by serologic antibody levels.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>serologic correlate of protection</obo:IAO_0000118>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>serologic correlated profile of immune protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000859 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000859">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000857"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000859</metadata:prefixIRI>
        <obo:IAO_0000115>Correlated profile of immune protection that is reflected by a cell mediated immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>cell mediated immune correlate of protection</obo:IAO_0000118>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>cell mediated correlated profile of immune protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000860 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000860">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000804"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000860</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine effectiveness is an effectiveness associated with a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>Hadler TC, et al. Immunization in developing countries. In: Vaccines. Editors: Plotkin S, et al. 2008. p1542-71.</obo:IAO_0000119>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccine effectiveness</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000862 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000862">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010632"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000862</metadata:prefixIRI>
        <obo:IAO_0000115>Canada is a country that exists in north America.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>Canada</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000863 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000863">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000649"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001074"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5867"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000863</metadata:prefixIRI>
        <obo:IAO_0000116>In vitro-cultured supernatant antigens, reduce clinical disease</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Pirodog</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=434</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0001818>434</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5867"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pirodog vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000864 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000864">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000864</metadata:prefixIRI>
        <obo:IAO_0000115>a licensed status that occurs in Canada.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>Canada licensed vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000865 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000865">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_836"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_836"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000865</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Porphyromonas gulae infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_836"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porphyromonas gulae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000866 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000866">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000714"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002495"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000690"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000866</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Fluviral S/F</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=571</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>571</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluviral S/F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000867 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000867">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000714"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000869"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000867</metadata:prefixIRI>
        <obo:IAO_0000115>Influvac is an Influenza virus vaccine that is manufactured by Solvay Pharma.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Influvac</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=597</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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    <!-- http://purl.obolibrary.org/obo/VO_0000870 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>Babesia bigemina vaccine by local veterinary institutes</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000871 -->

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        <obo:IAO_0000116>Canarypox virus-vectored vaccine</obo:IAO_0000116>
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    <!-- http://purl.obolibrary.org/obo/VO_0000872 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000873 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0000874 -->

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        <obo:IAO_0000115>Anthrax Spore Vaccine is a B. anthracis vaccine that is prepared with a relatively nonpathogenic, noncapsulated variant strain of B. anthracis, originally developed at the Onderstepoort Laboratory, Pretoria, South Africa. Further work was conducted in England, India and in many other countries. Vaccine Strain is Sterne 34F2. The vaccine is a suspension of viable Bacillus anthracis spores in saponin.</obo:IAO_0000115>
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        <rdfs:label>Anthrax Spore vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000875 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000876 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>pCMV/ER-PA83</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15293452</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=29</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>29</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pCMV/ER-PA83 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000878 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000878">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000752"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000878</metadata:prefixIRI>
        <obo:IAO_0000116>Canarypox virus-vectored vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>RECOMBITEKEquine WNV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=396</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>396</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RECOMBITEKEquine WNV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000879 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000879">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_836"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000879</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>Porphyromonas denticanis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000880 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000880">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010873"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000880</metadata:prefixIRI>
        <obo:IAO_0000115>pCLF4 is a Bacillus anthracis vaccine that contains the N-terminal region (amino acids [aa] 10-254) of Bacillus anthracis LF cloned into the pCI expression plasmid.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>pCLF4</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11401993</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:15068841</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=28</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010873"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>28</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pCLF4 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000881 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000881">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000972"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000881</metadata:prefixIRI>
        <obo:IAO_0000115>Equity Oestrus Control Vaccine for Horses is prepared from an analogue of gonadotropin releasing factor (GnRF) linked to a carrier protein. It has an adjuvant that enhances the level and duration of the immune response to GnRF with minimal injection site reactivity. It is used as an aid in the control of oestrus and oestrus-related behaviour in fillies and mares not intended for breeding.</obo:IAO_0000115>
        <obo:IAO_0000116>Peptide-protein conjugate and proprietary adjuvant (immunostimulating complex); control of estrus and estrus-related behavior</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Equity</obo:IAO_0000118>
        <obo:IAO_0000118>Equity Oestrus Control Vaccine for Horses</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: https://www.pfizeranimalhealth.com.au/products/352/equityreg-oestrus-control-vaccine.aspx</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000972"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equity vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000882 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000882">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000578"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000868"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000882</metadata:prefixIRI>
        <obo:IAO_0000118>single-dose Vaxigrip</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>single-dose Vaxigrip vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000883 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000883">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000578"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000868"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000576"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000883</metadata:prefixIRI>
        <obo:IAO_0000116>The difference between single-dose and multi-dose Vaxigrip is that multi-dose Vaxigrip contains preservative thimoseral.</obo:IAO_0000116>
        <obo:IAO_0000116>We still have not made it defined class since we still need to figure out how to represent multi-dose vs. single dose. The previous method discussed brief needs vetting. --YH</obo:IAO_0000116>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>multi-dose Vaxigrip</obo:IAO_0000118>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000576"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>multi-dose Vaxigrip vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000884 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000884">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000093"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000884</metadata:prefixIRI>
        <obo:IAO_0000115>A mineral salt vaccine adjuvant that is composed of some aluminum compound.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>aluminum vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000885 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000885">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000415"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000885</metadata:prefixIRI>
        <obo:IAO_0000115>a role inhers in a vaccine component that when added into a vccine formmulation, it can prevent the growth of bacteria or fungi that inadvertently may be introduced into the vaccine during administrating process or the manufacturing process.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>P73 Chapter 6, Vaccine 5th edition by Plotkin, S. et al.</obo:IAO_0000119>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:comment>The CFR requires that, with certain defined exceptions, preservatives must be added to mulitdose vials of vaccine. (P73 Chapter 6, Vaccine 5th edition by Plotkin, S. et al.)</rdfs:comment>
        <rdfs:label>vaccine preservative role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000886 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000886">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000886</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that located in the mouth</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>oral route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000887 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000887">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000887</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that inject the material(such as vaccines, allergens) into the skin itself.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>intradermal injection route</obo:IAO_0000118>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intradermal route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000888 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000888">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000851"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000888</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>phenol vaccine preservative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000889 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000889">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000964"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000889</metadata:prefixIRI>
        <obo:IAO_0000116>Recombinant ApxII, TbpB, CysL, OmlA(1), and OmlA(2) proteins</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>PleuroStar APP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=421</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>421</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PleuroStar APP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000891 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000891">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000851"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000885"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000891</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000885"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>phenoxy ethanol vaccine preservative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000897 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000897">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000011"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000897</metadata:prefixIRI>
        <obo:IAO_0000115>Age at vaccination is the age of an experiment animal at the time of vaccination.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>age at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000898 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000898">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000909"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_77054"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001079"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000898</metadata:prefixIRI>
        <obo:IAO_0000116>Culture-derived schizonts</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_77054"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Theileria annulata vaccine by local veterinary institutes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000899 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000899">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000899</metadata:prefixIRI>
        <obo:IAO_0000115>Dose is a measurement data that measures the quantity of something that may be eaten by or administered to an organism, or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses.</obo:IAO_0000115>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://en.wikipedia.org/wiki/Dose_%28biochemistry%29</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000984"/>
        <rdfs:comment>obsolete on 2/1/2020, using the OBI dose term (OBI_0000984) instead.</rdfs:comment>
        <rdfs:label>obsolete dose</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000900 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000900">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000984"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000900</metadata:prefixIRI>
        <obo:IAO_0000115>A dose of a virulent pathogen used for a vaccine challenge process.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>challenge dose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000902 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000902">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000460"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003143"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000902</metadata:prefixIRI>
        <obo:IAO_0000116>Canarypox virus-vectored vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>PROTEQ-FLU (European Union)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=393</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>393</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PROTEQ-FLU vaccine (European Union)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000903 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000903">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000708"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000062"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000707"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000903</metadata:prefixIRI>
        <obo:BFO_0000062 rdf:resource="http://purl.obolibrary.org/obo/VO_0000707"/>
        <obo:IAO_0000115>Secondary vaccination is a vaccination that is performed immediately after the primary or the first vaccination.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Thom Todd</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>secondary vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000906 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000906">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000906</metadata:prefixIRI>
        <obo:IAO_0000115>Protozoan vaccine that is used to protect against Eimeria spp. (Eimeria) infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000907 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000907">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110034"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000907</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>surface antigens from the zona pellucida</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000909 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000909">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5874"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5874"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000909</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5874"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Theileria annulata vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000910 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000910">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000091"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000713"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000091"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000713"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000910</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine allergen is a material entity that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals who has been vaccinated with a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf</obo:IAO_0000119>
        <obo:RO_0000091 rdf:resource="http://purl.obolibrary.org/obo/VO_0000713"/>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>vaccine allergen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000911 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000911">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000492"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000911</metadata:prefixIRI>
        <obo:IAO_0000115>passive immunization that Immunity is transferred from mother to fetus through placental transfer of IgG or colostral transfer of IgA.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>http://pathmicro.med.sc.edu/ghaffar/immunization-ver2.htm</obo:IAO_0000119>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>passive immunization using natural maternal antibody</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000912 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000912">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000910"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000912</metadata:prefixIRI>
        <obo:IAO_0000115>chicken egg protein allergen is a vaccine allergen that is composed of chicken egg protein.</obo:IAO_0000115>
        <obo:IAO_0000116>Egg protein may come from NCIS thesaurus egg - poultry, combination
of minimal anatomy terminology and NCBI taxonomy... Eventually, this term chicken egg protein allergen may become a cross product of sevreal ontology terms.</obo:IAO_0000116>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>chicken egg protein allergen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000913 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000913">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000910"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000913</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>latex vaccine allergen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000915 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000915">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000910"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000915</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>gelatin vaccine allergen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000916 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000916">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000910"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000916</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>protamine sulfate vaccine allergen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000917 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000917">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000910"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000917</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>polymyxin B vaccine allergen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000918 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000918">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000652"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000843"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011068"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000918</metadata:prefixIRI>
        <obo:IAO_0000116>Canarypox virus-vectored vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>EURIFEL FeLV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=405</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011068"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <obo:VO_0001818>405</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>EURIFEL FeLV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000919 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000919">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000179"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000237"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110034"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000237"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000919</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine component that is used as antigen to produce an immune responce protect against the specific pathogen or disease.</obo:IAO_0000115>
        <obo:IAO_0000116>This is a modified or partial form of the virus, bacteria or the toxin that causes the disease against which the vaccine protects. The vaccine antigen is altered from its original form so it no longer causes disease but it can produce an immune response.(Vaccine components FactSheet of NCIRS)</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine antigenic component</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000237"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>To create this term for cover some other vaccines such as cancer vaccine and so on.</rdfs:comment>
        <rdfs:label>vaccine antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000920 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000920">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000856"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000920</metadata:prefixIRI>
        <obo:IAO_0000115>a cell culture residual in vaccine that is bovine albumin.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>bovine albumin cell culture residual in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000921 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000921">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000856"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000921</metadata:prefixIRI>
        <obo:IAO_0000115>a cell culture residual in vaccine that is bovine serum.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>bovine serum cell culture residual in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000922 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000922">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003035"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_64220"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000922</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_64220"/>
        <obo:IAO_0000115>a vaccine stablizer that is based on monosodium glutamate. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C5H8NNaO4</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>http://www.novaccine.com/vaccine-ingredients/results.asp?sc=13</rdfs:comment>
        <rdfs:label>monosodium glutamate stabliizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000923 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000923">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000649"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000932"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000923</metadata:prefixIRI>
        <obo:IAO_0000116>Modified live virus</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>RECOMBITEK Corona MLV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=407</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0001818>407</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RECOMBITEK Corona MLV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000924 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000924">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000851"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000885"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000924</metadata:prefixIRI>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000885"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>glutaraldehyde vaccine additive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000925 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000925">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5865"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5865"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000925</metadata:prefixIRI>
        <obo:IAO_0000116>Infected blood from splenectomized calves</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5865"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Babesia bovis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000926 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000926">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000856"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000926</metadata:prefixIRI>
        <obo:IAO_0000115>a cell culture residual in vaccine that is human albumin.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>human albumin cell culture residual in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000927 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000927">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000856"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000927</metadata:prefixIRI>
        <obo:IAO_0000115>a cell culture residual in vaccine that is human serum.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>human serum cell culture residual in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000928 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000928">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000645"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000649"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_13488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9654"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000928</metadata:prefixIRI>
        <obo:IAO_0000116>Reference: http://www.raboral.com/</obo:IAO_0000116>
        <obo:IAO_0000116>Vaccinia virus recombinant</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Raboral</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=403</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_13488"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9654"/>
        <obo:VO_0001818>403</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Raboral vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000929 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000929">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000929</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine stabilizer that is a polysorbate 20. It encourages the suspension of one liquid in another and has mild toxicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Reference: http://www.sciencelab.com/msds.php?msdsId=9926640 </rdfs:comment>
        <rdfs:comment>http://www.novaccine.com/vaccine-ingredients/results.asp?sc=95</rdfs:comment>
        <rdfs:label>polysorbate 20 vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000930 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000930">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000310"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000930</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine emulsifier that uses polysorbate 80, also known as polyoxyethylene sorbitan monooleate or Tween(TM) 80.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Tween 80 vaccine emulsifier</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.wisegeek.org/what-is-polysorbate-80.htm</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Tween 80 is an amber-colored, viscous liquid with a slightly bitter taste. The product is a derivative of sorbitol and oleic acid.</rdfs:comment>
        <rdfs:label>polysorbate 80 vaccine emulsifier</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000931 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000931">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000856"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000931</metadata:prefixIRI>
        <obo:IAO_0000115>a cell culture residual in vaccine that is residual protein from cell culture. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine residual protein from cell culture</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000932 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000932">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004897"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000932</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>canine coronavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000933 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000933">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83334"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000933</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3095</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>3095</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83334"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli CS3 in PLGA microspheres</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000934 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000934">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003034"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_30911"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000934</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_30911"/>
        <obo:IAO_0000115>a vaccine stabilizer that is specifically made by sorbitol.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>glucitol</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Sorbitol, also known as glucitol, is a sugar alcohol that the human body metabolizes slowly. It can be obtained by reduction of glucose, changing the aldehyde group to a hydroxyl group. Sorbitol is found in apples, pears, peaches, and prunes. It is synthesized by sorbitol-6-phosphate dehydrogenase, and converted to fructose by succinate dehydrogenase and sorbitol dehydrogenase. Succinate dehydrogenase is an enzyme complex that participates in the citric acid cycle. (wikipedia)</rdfs:comment>
        <rdfs:label>sorbitol vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000935 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000935">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_42890"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000935</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_42890"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Sarcocystis neurona vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000936 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000936">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000936</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is made of a TK-negative (TK -) and gI/gE-negative (gI/gE -) pseudorabies virus (PRV) mutant to protect pigs against Aujeszky&apos;s disease. Aujeszky&apos;s disease is also known as pseudorabies. It is a disease primarily of pigs and is caused by porcine herpesvirus 1. This disease is characterized by respiratory, reproductive and nervous signs.</obo:IAO_0000115>
        <obo:IAO_0000116>gE- and thymidine kinase-deleted
marker vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Suvaxyn Aujeszky</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=389</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>389</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Suvaxyn Aujeszky vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000937 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000937">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000856"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000937</metadata:prefixIRI>
        <obo:IAO_0000115>a cell culture residual in vaccine that is sucrose albumin.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>sucrose albumin cell culture residual in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000938 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000938">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000938</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is derived from Xanthomonas campestris, has a pentasaccharide repeating unit structure, and its terminus contains a mannose moiety which acts as a toll-like receptor 2 agonist.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:19608270</obo:IAO_0000119>
        <obo:IAO_0000119>http://www.sciencedirect.com/science/article/pii/S0142961209006371</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>xanthan gum vaccine ajuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000939 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000939">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000856"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000939</metadata:prefixIRI>
        <obo:IAO_0000115>a cell culture residual in vaccine that is from yeast extract.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>yeast extract cell culture residual in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000940 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000940">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000856"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000940</metadata:prefixIRI>
        <obo:IAO_0000115>a cell culture residual in vaccine that is yeast protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>yeast protein cell culture residual in vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000941 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000941">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000645"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000941</metadata:prefixIRI>
        <obo:IAO_0000116>DNA vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Apex-IHN</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=410</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8015"/>
        <obo:VO_0001818>410</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Apex-IHN vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000942 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000942">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000942</metadata:prefixIRI>
        <obo:IAO_0000118>DTP-Hib vaccine</obo:IAO_0000118>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000137"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Diphtheria-Tetanus-Pertussis-Haemophilus b vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000943 -->

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        <rdfs:subClassOf>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Diphtheria-Tetanus-Poliovirus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000944 -->

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        <obo:IAO_0000118>V. cholerae and E. coli vaccine</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vibrio cholerae and E. coli vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000945 -->

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        <obo:IAO_0000115>A Measles virus vaccine that is also used against Rubella virus infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_1000000>measles and rubella virus vaccine</obo:VO_1000000>
        <obo:VO_1000001>M/R</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Measles-Rubella vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000946 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000946</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against, Diphtheria, Tetanus, Pertussis (whooping cough), Polio, Hepatitis B, and Haemophilus influenzae type b.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000947 -->

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        <obo:IAO_0000116>Live flavivirus chimera vaccine</obo:IAO_0000116>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PreveNile vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000948 -->

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        <obo:IAO_0000115>a bacterial vaccine against S. equi infection</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus equi vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000949 -->

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        <obo:IAO_0000115>a bacterial vaccine against Mycoplasma gallisepticum infection</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma gallisepticum vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000950 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000950</metadata:prefixIRI>
        <obo:IAO_0000118>Hepatitis A virus-Typhoid vaccine</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella typhi-Hepatitis A vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000951 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000951</metadata:prefixIRI>
        <obo:IAO_0000116>Baculovirus recombinant E2 protein without emulsion</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Bayovac CSF E2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=391</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>391</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bayovac CSF E2 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000952 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000952</metadata:prefixIRI>
        <obo:IAO_0000118>Tick-borne virus vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11318"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dhori virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000953 -->

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        <obo:IAO_0000115>Pharyngeal mucosal route is an oral route of administration.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Thom Todd</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>pharyngeal mucosal route</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000954 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000954</metadata:prefixIRI>
        <obo:IAO_0000116>Chimera virus on NDV backbone; field trials in 2007</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=400</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>400</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Intervet avian influenza virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000955 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000955">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
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        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>host survival to pathogen challenge after vaccination</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000956 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000956</metadata:prefixIRI>
        <obo:IAO_0000115>a B. abortus vaccine that uses a conjugate vaccine format</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus conjugate vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000957 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000957</metadata:prefixIRI>
        <obo:IAO_0000115>a B. abortus vaccine that uses a recombinant vector. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus recombinant vector vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000958 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000958</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Herpes simplex virus type 1.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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        <obo:IAO_0000118>Herpes simplex virus type 1</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus type 1 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000960 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>killed infectious bursal disease virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000961 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated infectious bursal disease virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000962 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000962</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli vaccine that uses a live mutant by knocking out one gene(s) from a wild type E. coli.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant E. coli mutant vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000963 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000963</metadata:prefixIRI>
        <obo:IAO_0000115>an E. coli vaccine that uses toxoid antigen</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli toxoid vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000965 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>potato expressed E. coli LB-T vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0000966 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000966</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli vaccine that uses a recombinant vaccine vector to express an E. coli antigen(s)</obo:IAO_0000115>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant vaccine vector E. coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000967 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000967">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000966"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000967</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>rBCG-Stx2B</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rBCG-Stx3B vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000968 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000968">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000968</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pBLUESCRIPT.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Davidson College - pBLUESCRIPT: Plasmids and Phages Combine For pBluescript [http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/Keogh/plasmids.html]</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Derived from pUC vectors; cross between phages and plasmids and therefore in a special category called &quot;phagemids&quot; (Davidson College - pBLUESCRIPT)</rdfs:comment>
        <rdfs:comment>The plasmid length is: 2961</rdfs:comment>
        <rdfs:label>pBLUESCRIPT DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>DNAVaxDB Plasmid ID: 180</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000969 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000969">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000969</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label nkCMVint.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>A pUC-18-based plasmid; also contains intron A and an SV40 polyadenylation termination signal sequence. It has a CMV promoter.</rdfs:comment>
        <rdfs:label>nkCMVint DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>DNAVaxDB Plasmid ID: 181</rdfs:seeAlso>
        <rdfs:seeAlso>PMID: 9234529</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000970 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000970">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000970</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli Tir protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000972 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000972">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/FMA_12278"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000972</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>luteinizing hormone-releasing hormone</obo:IAO_0000118>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>LHRH</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000973 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000973">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000973</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli Shiga toxin 2B vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000974 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000974">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000041"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000974</metadata:prefixIRI>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated E. coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000975 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000975">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000975</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli vaccine against uropathogenic E. coli infections</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>UPEC vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>uropathogenic E. coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000976 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000976">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000976</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli vaccine against extraintestinal pathogenic E. coli infections</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>ExPEC vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>extraintestinal pathogenic E. coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000977 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000977">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000977</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli vaccine against enterohemorrhagic E. coli infections</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>EHEC vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>enterohemorrhagic E. coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000978 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000978">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010394"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000978</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5555</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm335836.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5555</obo:VO_0001818>
        <obo:VO_0003099>Flublok</obo:VO_0003099>
        <obo:VO_0003160>For active immunization against disease caused by influenza virus subtypes A and type B contained in the vaccine. Flublok is approved for use in persons 18 years of age and older.</obo:VO_0003160>
        <obo:VO_0003162>125285</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197911"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flublok</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000979 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000979">
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000979</metadata:prefixIRI>
        <obo:IAO_0000116>Live or inactivated gE-deleted marker vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=392</obo:IAO_0000119>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovilis IBR Marker vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000980 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0000981 -->

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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000512"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000985</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine that is used to protect against fowl pox virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>fowl pox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000986 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000986">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000986</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000461"/>
        <rdfs:label>obsolete avian influenza vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000987 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000987">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003537"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000987</metadata:prefixIRI>
        <obo:IAO_0000115>Viral vaccine that is used to protect against Bovine herpesvirus 1 infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>BHV-1 vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>bovine rhinotracheitis vaccine</obo:IAO_0000118>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bovine herpesvirus 1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000988 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000988">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001061"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5875"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001058"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000988</metadata:prefixIRI>
        <obo:IAO_0000116>Infection followed by drug treatment</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5875"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Theileria parva vaccine by local veterinary institutes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000990 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000990">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000990</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118>bovine parainfluenza 3 vaccine</obo:IAO_0000118>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine parainfluenza 3 virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000991 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000991">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000991</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pDONR221. The plasmid length is 4762.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/2394/</obo:IAO_0000119>
        <obo:IAO_0000119>Invitrogen: http://tools.invitrogen.com/content/sfs/manuals/gateway_pdonr_vectors.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>pDONR221 Sequence: http://tools.invitrogen.com/content/sfs/vectors/pdonr221_seq.txt</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pDONR221 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000992 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000992">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000992</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCN3. The plasmid promoter is CMV.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCN3 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 19596416; PMID: 21059395.</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000993 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000993">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000993</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label V1R.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>V1R DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID:  11797011; PMID: 15258286</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000994 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000994">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000994</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000995 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000995">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000995</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pVAC1 3.0. The manufacturer is Invitrogen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pVAC1 3.0 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 20884037</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000996 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000996">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000655"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000907"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9850"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001069"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000996</metadata:prefixIRI>
        <obo:IAO_0000115>A contraceptive vaccine that has proven highly effective in deer and can be used to control populations.</obo:IAO_0000115>
        <obo:IAO_0000116>Crude ZPA preparation; supplied to research groups only</obo:IAO_0000116>
        <obo:IAO_0000116>no longer available</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>SpayVac</obo:IAO_0000118>
        <obo:IAO_0000119>http://terramar.bc.ca/</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000907"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9850"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SpayVac vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000997 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000997">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000997</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pSin-CMV-Vac. The promoter is CMV.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSin-CMV-Vac DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 22702835; PMID: 23637502</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000998 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000998">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000998</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pGACAG. The promoter is CAG and the antibiotics resistance gene is kanamycin.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pGACAG DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 17203206</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000999 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0000999">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0000999</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pVCL1012. The promoter is HCMV and the manufacturer is Vical Inc.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pVCL1012 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 15652666</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001000</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pSCA1.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSCA1 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 22819169</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001002</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label phCMV1.  This plasmid is 4200 base pairs long, has a CMV promoter, contains kanamycin and neomycin antibiotics resistance genes, and is manufactured by Genlantis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.genlantis.com/faq-phcmv.html</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>phCMV1 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 19540885</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001003</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCJ-3.  This plasmid has a CMV promoter and a kanamycin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCJ-3 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 16949850</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001004</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1/V5-His.  This plasmid has a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcDNA3.1/V5-His DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 22445688</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000023"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001005</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pSecTag2 C.  This plasmid is 5167 base pairs long, has a CMV promoter and ampicillin and zeocin resistance genes.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://tools.invitrogen.com/content/sfs/manuals/psectag2_man.pdf</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSecTag2 C DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001006"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001007</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pBC12/CMV/IL-2.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>NIH AIDS Reagent Program - pBC12/CMV/IL-2: [https://www.aidsreagent.org/reagentdetail.cfm?t=expression_vectors&amp;id=159]</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Derived from plasmid pBC12/CMV; expresses IL-2 (NIH AIDS Reagent Program - pBC12/CMV/IL-2). Its length is: 4732.</rdfs:comment>
        <rdfs:label>pBC12/CMV/IL-2 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>DNAVaxDB Plasmid ID: 182</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001008">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000649"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001083"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5741"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001008</metadata:prefixIRI>
        <obo:IAO_0000116>Cultured trophozoites, reduces disease and cyst shedding</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Giardiavax</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=432</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0001818>432</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Giardiavax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001009</metadata:prefixIRI>
        <obo:IAO_0000115>The plant-based Newcastle disease virus vaccine is a Newcastle disease virus vaccine that is developed by Dow AgroSciences LLC. It uses technology discovered at Washington University. It is the first plant-made animal vaccine approved for sale in the United States.</obo:IAO_0000115>
        <obo:IAO_0000116>HN recombinant produced in plant cell lines (registered but not on market)</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>plant-based Newcastle disease virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001012">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003546"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001012</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>classical swine fever virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000731"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_52071"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8781"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11041"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000700"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001013</metadata:prefixIRI>
        <obo:IAO_0000115>A Measles-Mumps-Rubella vaccine that is manufactured by Sanofi Aventis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Morupar</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8781"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11041"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Morupar vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001014">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001014</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated quality of a bacterial vaccine strain. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete bacterial vaccine organism live attenuated</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001015">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001015</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated quality of a virus vaccine strain. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete viral vaccine organism live attenuated</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001016</metadata:prefixIRI>
        <obo:IAO_0000116>Fowlpox virus vectored</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Vectormune FP-ND</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=399</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>399</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vectormune FP-ND vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012162"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001017</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated vaccine that protects against Marek&apos;s disease virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Marek&apos;s; disease virus</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated Marek&apos;s disease virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001018">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001222"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001018</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated viral vaccine that protects aganist Newcastle disease virus infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated Newcastle disease virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001019">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001513"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001019</metadata:prefixIRI>
        <obo:IAO_0000115>an avian reovirus vaccine that using live attenauted reovirus. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated avian reovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000906"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001020</metadata:prefixIRI>
        <obo:IAO_0000116>Sporulated oocysts of several or all of the avian species</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Advent</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=424</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>424</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Advent vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001021">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000389"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000389"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10786"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001021</metadata:prefixIRI>
        <obo:IAO_0000115>a feline panleukopenia virus vaccine where the virus used is live attenuated. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10786"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated feline panleukopenia virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001022</metadata:prefixIRI>
        <obo:IAO_0000115>Megan Vac1 is a Salmoneela vaccine that consists of a double gene-deleted S. enterica serovar Typhimurium strain and is designed for protection of broilers to reduce Salmonella contamination.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Megan Vac1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=423</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.fda.gov/ohrms/dockets/dockets/00n0504/00N-0504_emc-001650-02.pdf</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>423</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Megan Vac1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001023 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001023">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001023</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine vector that uses TB vaccine BCG as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>BCG vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 33892</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001024">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000461"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000461"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001024</metadata:prefixIRI>
        <obo:IAO_0000115>an avian influenza vaccine that uses inactivated viral organism</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated avian influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001025 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001025">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001121"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001025</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a vesicular stomatitis virus (VSV) as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vesicular stomatitis virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11276</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000645"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000820"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8015"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001174"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001026</metadata:prefixIRI>
        <obo:IAO_0000116>Killed oral vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>AquaVac Furuvac</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=414</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8015"/>
        <obo:VO_0001818>414</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AquaVac Furuvac vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001028">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001034"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001028</metadata:prefixIRI>
        <obo:IAO_0000115>a parasite vaccine vector using a live attenuated Leishmania tarentolae strain.  </obo:IAO_0000115>
        <obo:IAO_0000117>Carly Martin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Leishmania tarentolae vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 5689</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001029</metadata:prefixIRI>
        <obo:IAO_0000119>PMID:23969885</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous dendritic cell melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001030">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001030</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete vaccine-induced mouse immune response</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001031">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001031</metadata:prefixIRI>
        <obo:IAO_0000112>WEB: http://www.ncbi.nlm.nih.gov/pubmed/21907709</obo:IAO_0000112>
        <obo:IAO_0000115>a bacterial vaccine vector using a live attenuated Salmonella enterica strain SL3261.</obo:IAO_0000115>
        <obo:IAO_0000117>Carly Martin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Salmonella typhimurium SL3261 vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001032">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001032</metadata:prefixIRI>
        <obo:IAO_0000112>WEB: http://www.ncbi.nlm.nih.gov/pubmed/21964456</obo:IAO_0000112>
        <obo:IAO_0000115>a bacterial vaccine vector using a live attenuated Edwardsiella tarda strain EIB202</obo:IAO_0000115>
        <obo:IAO_0000117>Carly Martin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Edwardsiella tarda EIB202 vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 498217</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001033">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5866"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5866"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001033</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5866"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Babesia bigemina vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000599"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001034</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine vector that uses a parasite as the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Carly Martin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>parasite vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001035">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29486"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000601"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29486"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001035</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine against Yersinia ruckeri infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29486"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia ruckeri vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001036</metadata:prefixIRI>
        <obo:IAO_0000112>WEB: http://www.ncbi.nlm.nih.gov/pubmed/23403993</obo:IAO_0000112>
        <obo:IAO_0000115>a bacterial vaccine vector using a live attenuated Streptococcus gordonii vaccine vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Carly Martin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Streptococcus gordonii vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 1302</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001037 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001037">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001037</metadata:prefixIRI>
        <obo:IAO_0000112>WEB: http://www.ncbi.nlm.nih.gov/pubmed/16823926</obo:IAO_0000112>
        <obo:IAO_0000115>a bacterial vaccine vector using a live attenuated Bordetella pertussis BPZE as a vaccine vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Carly Martin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis BPZE vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001038">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001038</metadata:prefixIRI>
        <obo:IAO_0000112>WEB: http://www.ncbi.nlm.nih.gov/pubmed/9767712</obo:IAO_0000112>
        <obo:IAO_0000115>a bacterial vaccine vector using the HS93Tox- mutant of the serovar 7 strain of Actinobacillus pleuropneumoniae. This mutant lacks the genes encoding the toxin ApxA and the post-translational activating protein ApxC, but still has genes required for secretion, making it a good vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Carly Martin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Actinobacillus pleuropneumoniae HS93Tox vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001143"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001040</metadata:prefixIRI>
        <obo:IAO_0000115>an Avipox virus vaccine vector that uses a fowlpox virus as the vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>fowlpox virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10261</rdfs:seeAlso>
        <rdfs:seeAlso>pmid: 10729156</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001041">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000068"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001041</metadata:prefixIRI>
        <obo:IAO_0000115>A Listeria monocytogenes vaccine vector that uses the highly attenuated LM1-2 strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 23027427</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>L. monocytogenes LM1-2 vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001042">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000283"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001042</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>BHV-4 vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000118>bovine herpesvirus 4 vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 23830977; PMID: 23300989; PMID: 21320537; PMID: 24752229</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>BoHV-4 vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10385</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001043">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001143"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001043</metadata:prefixIRI>
        <obo:IAO_0000115>an Avipox virus vaccine vector that uses an attenuated canarypox virus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>Poulet et al. 2007, PubMed PMID: 17227690.</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Canarypox</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>canarypox vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 44088</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001044">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001044</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine vector that uses an attenuated Vibrio cholerae strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 9529093</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Vibrio cholerae vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 666</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001045">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001045</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses an avian paramyxovirus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>avian paramyxovirus type 3 vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 21525340</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>APMV-3 vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 207246</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001046">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000283"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001046</metadata:prefixIRI>
        <obo:IAO_0000115>a herpesvirus vaccine vector that uses a herpes simplex virus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>HSV vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 22713696; PMID: 19428888; PMID: 20835362; PMID: 16996101</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001047</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that uses the simian adenovirus ChAd63 strain.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 22275401; PMID: 23526949; PMID: 22363582</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>simian adenovirus ChAd63 vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 413684</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001048 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001048">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001146"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001048</metadata:prefixIRI>
        <obo:IAO_0000115>an orthopoxvirus vaccine vector that uses an attenuated Raccoon poxvirus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 22921740</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>raccoon poxvirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10256</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001049">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000949"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000861"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001049</metadata:prefixIRI>
        <obo:IAO_0000116>Live temperature-sensitive mutant strain; eye drop administration</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Vaxsafe MS</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=418</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>418</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaxsafe MS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000283"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001050</metadata:prefixIRI>
        <obo:IAO_0000115>A herpesevirus vaccine vector that uses an established live-virus vaccine against Aujeszky&apos;s disease of swine, pseudorabies virus (PrV) strain Bartha (PrV-Ba), to serve as vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>PrV vaccine vector </obo:IAO_0000118>
        <obo:IAO_0000118>Suid herpesvirus 1 strain Bartha vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 24431235</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pseudorabies virus strain Bartha vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 1006205</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001051</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that uses a porcine adenovirus 3 strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>PAV3 vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 11402666; PMID: 21179494; PMID: 10091994; PMID: 12954206; PMID: 17565687</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>porcine adenovirus 3 vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 35265</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001052 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001052">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001052</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a poliovirus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>PV vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 19003009; PMID: 12423772; PMID: 17196342</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>poliovirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 138950</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001053 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001053">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000649"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001074"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5867"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001053</metadata:prefixIRI>
        <obo:IAO_0000116>In vitro-cultured supernatant antigens, reduce clinical disease</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Nobivac Piro</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5867"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nobivac Piro vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000948"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1336"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001054</metadata:prefixIRI>
        <obo:IAO_0000116>Live submucosal vaccine; deletions in aroA gene</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Equilis StrepE</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=416</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>416</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1336"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equilis StrepE vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001055">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001055</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that uses a chimpanzee adenovirus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>chimpanzee adenovirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 310542</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001056 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001056">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001056</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a measles virus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>MV vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 24084235; PMID: 24606680; PMID: 23642239; PMID: 23550539; PMID: 23516477</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>measles virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001057 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001057">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001057</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a Coxsackievirus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 20824074; PMID: 11115722; PMID: 19053211; PMID: 20088713; PMID: 21389776; PMID: 19941986; PMID: 11160741</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Coxsackievirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 12066</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001059 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001059">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000283"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001059</metadata:prefixIRI>
        <obo:IAO_0000115>a poxvirus vaccine vector that uses an attenuated Oka varicella virus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>Human herpesvirus 3 strain Oka vaccine vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 10720546; PMID: 16615495; PMID: 18053621</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Oka varicella vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 341980</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001060">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001060</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a NewCastle virus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>NDV vaccine vector </obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 23845804</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Newcastle disease virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001061">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5875"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5875"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001061</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5875"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Theileria parva vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001062">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001062</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a myxoma virus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 10627521; PMID: 12951040; PMID: 14972520; PMID: 8719525; PMID: 12057600; PMID: 18474552; PMID: 21835800; PMID: 22244980</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>myxoma virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10273</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001063 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001063">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001063</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a Maraba virus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 24322333</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Maraba virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 1046251</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001064">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001064</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine vector that uses an attenuated Mycobacterium smegmatis strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 22546648; PMID: 21900527</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium smegmatis vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 1772</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001065 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001065">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001065</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001066">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001066</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine vector that uses an attenuated Lactobacillus gasseri strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 21375708; PMID: 20722604; PMID: 21900526</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Lactobacillus gasseri vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 1596</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001067 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001067">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000283"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001067</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>HVT vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000118>Meleagrid herpesvirus 1 vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 22845318</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>herpesvirus of turkey vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 37108</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001068 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001068">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001046"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001068</metadata:prefixIRI>
        <obo:IAO_0000115>A Herpes simplex virus vaccine vector that uses a virus type 1 strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>HSV-1 vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 19428888</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus vaccine 1 vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10298</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001070 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001070">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001070</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine vector that uses an E. coli strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 24746937</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>E. coli vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 562</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001071 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001071">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000645"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000823"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_13489"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8015"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_55601"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001174"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001071</metadata:prefixIRI>
        <obo:IAO_0000116>Killed oral vaccine</obo:IAO_0000116>
        <obo:IAO_0000116>Reference: http://www.spaquaculture.com/default.aspx?pageid=553</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>AquaVac Vibrio</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=415</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_13489"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8015"/>
        <obo:VO_0001818>415</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_55601"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AquaVac Vibrio vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001072 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001072">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001072</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a duck enteritis virus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>Anatid herpesvirus 1 vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 23267833</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>duck enteritis virus vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 104388</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001073">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000283"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001073</metadata:prefixIRI>
        <obo:IAO_0000115>a herpesvirus vaccine vector that uses a CMV virus strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>Cytomegalovirus vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 23811402</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>CMV vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10358</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001074 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001074">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5867"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5867"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001074</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5867"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Babesia canis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001075">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001075</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine vector that uses a Salmonella typhi strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Salmonella typhi vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 90370</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001076</metadata:prefixIRI>
        <obo:IAO_0000115>a recombinant vector vaccine that uses a homologous vector, i.e., when the target species of the vaccine is a natural host for the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.biosafety.be/GT/Regulatory/Veterinary_vaccines/EMEA_000404en.pdf</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant homologous vector vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001077 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001077">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2109"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000604"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2109"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001077</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine against Mycoplasma synoviae infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2109"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma synoviae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001078 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001078">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001078</metadata:prefixIRI>
        <obo:IAO_0000115>a recombinant vector vaccine that uses a homologous vector, i.e., when the target species of the vaccine is not one of the natural hosts for the vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.biosafety.be/GT/Regulatory/Veterinary_vaccines/EMEA_000404en.pdf</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant heterologous vector vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/FMA_12278"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001080</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>Androstenedione</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001081 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001081">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001081</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that uses an Adenovirus serotype 5 strain.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>human adenovirus 5 vaccine vector</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>adenovirus serotype 5 vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 28285</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001082 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001082">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001082</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that contains a deletion of the gp64 gene. As a result of the deletion, this vector is unable to propagate infection from cell to cell, and this defect results from both a severe reduction in the production of budded virions and the absence of GP64 on virions.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 17989172</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>AcMNPV vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 46015</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001083 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001083">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5741"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5741"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001083</metadata:prefixIRI>
        <obo:IAO_0000115>protozoan vaccine that is used to protect against Giardia intestinalis infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Giardia duodenalis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001084 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001084">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001084</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a baculovirus as the vector </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 22705893</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>baculovirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10469</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001085 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001085">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000573"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001085</metadata:prefixIRI>
        <obo:IAO_0000115>Chlamydia bacterial vaccine against C. abortus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001086 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001086">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001086</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that uses a complex adenovirus as the vector strain.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>CAdVax vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 19776190; PMID: 18480438; PMID: 17634508; PMID: 18216185; PMID: 16501083</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>complex adenovirus vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001087 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001087">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001087</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that uses a human adenovirus as the vector strain.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>HAd vaccine vector</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 16297508; PMID: 15761255</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>human adenovirus vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001088 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001088">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001088</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a murine leukemia virus as the vaccine vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Murine_leukemia_virus</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>murine leukemia viral vector vaccine</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11786</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001089 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001089">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001089</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>CDC recommendation of the use of  Influenza A (h1N1) 2009 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001090 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001090">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000546"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001090</metadata:prefixIRI>
        <obo:IAO_0000115>A population group that have priority for  vaccination when a vaccine is first available.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccination target group</obo:IAO_0000118>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>vaccinee priority group</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001091 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001091">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000461"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003143"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001091</metadata:prefixIRI>
        <obo:IAO_0000116>Chimera H5N3 virus, inactivated in oil-based adjuvant</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Poulvac FluFend I AI H5N3 RG</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=401</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>401</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Poulvac FluFend I AI H5N3 RG vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001093">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000600"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001093</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccinia vaccine vector that uses the highly attenuated NYVAC  as vector</obo:IAO_0000115>
        <obo:IAO_0000116>A highly attenuated vaccinia virus strain, NYVAC (vP866), was derived from a plaque-cloned isolate of the Copenhagen vaccine strain by the precise deletion of 18 open reading frames (ORFs) from the viral genome. Source: http://www.ncbi.nlm.nih.gov/pubmed/1566575</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 22930439;; PMID: 24069354; PMID: 1566575</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>NYVAC vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10249 (for Vaccinia virus Copenhagen)</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001094 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001094">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001094</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm</obo:IAO_0000119>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>pregnant women</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001095 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001095">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000492"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001095</metadata:prefixIRI>
        <obo:IAO_0000115>passive immunization by injecting a recipient with pre-made antibody, antitoxin, epitope, etc.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>passive immunization by injecting pre-made immune element</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001096">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000372"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001080"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000914"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001096</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine used to increase the fecundity in breeding ewes. Ovastim increases the number of multiple ovulations and therefore the number of multiple births.</obo:IAO_0000115>
        <obo:IAO_0000116>Increased ovulation/twinning</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Ovastim</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.virbac.co.nz/p-virbacnzpuben/display.aspx?srv=p-virbacnz&amp;typ=pub&amp;lang=en&amp;cmd=view&amp;style=styles/specie.xsl&amp;select=PRODUCT[@ID$eq$PRODUCT_264]&amp;affp=&amp;</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0001080"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ovastim vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001097">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000649"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001097</metadata:prefixIRI>
        <obo:IAO_0000116>Canarypox virus-vectored vaccine (HA and F antigens)</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>RECOMBITEK rDistemper</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=408</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0001818>408</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RECOMBITEK rDistemper vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001098 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001098">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001098</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm</obo:IAO_0000119>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>persons living with or providing care for infants aged &lt;6 months</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001099">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001099</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm</obo:IAO_0000119>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>health-care and emergency medical services personnel</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001100</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm</obo:IAO_0000119>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>persons aged 6 months--24 years</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001101">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000181"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001101</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm</obo:IAO_0000119>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>persons aged 25--64 years with  medical conditions at higher risk for influenza-related complications</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001102 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001102">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001102</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a retroviral strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 2839718</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>retroviral vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11632</rdfs:seeAlso>
        <rdfs:seeAlso>Vaxvec: 23</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001103">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001103</metadata:prefixIRI>
        <obo:IAO_0000115>Inactivation is a processual entity that produces inactive material.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>inactivation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001104">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001102"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001104</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>a retroviral vaccine vector where a Rous sarcoma virus (a retrovirus) is used</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Rous sarcoma virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11886</rdfs:seeAlso>
        <rdfs:seeAlso>Vaxvec: 20</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001105 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001105">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29546"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29546"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001105</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Lawsonia intracellularis infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29546"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lawsonia intracellularis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001106 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001106">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000447"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001106</metadata:prefixIRI>
        <obo:IAO_0000115>a poxvirus vaccine vector that uses a swinepox virus as the vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>swinepox virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10276</rdfs:seeAlso>
        <rdfs:seeAlso>PMID: 22515033; PMID: 21807055; PMID: 22884664; PMID: 23135159</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001107 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001107">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000600"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001107</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccinia virus vector that uses the Modified Vaccinia Ankara (MVA) virus. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 24933081</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Modified Vaccinia Ankara (MVA) virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 467144</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001108 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001108">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000447"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001108</metadata:prefixIRI>
        <obo:IAO_0000115>a poxvirus vaccine vector that uses an ORF virus which is a parapoxvirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>ORF virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10258</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001109 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001109">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000600"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001109</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccinia virus vector that uses the MVTT vaccine strain as the vector. MVTT is an attenuated vaccine strain. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>vaccinia virus TianTan vaccine vector</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>MVTT vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10253</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001110 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001110">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000372"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001080"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001212"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001110</metadata:prefixIRI>
        <obo:IAO_0000115>a fertility vaccine that enhance fertility in sheep.</obo:IAO_0000115>
        <obo:IAO_0000116>Linked to human serum albumin; increased ovulation/twinning</obo:IAO_0000116>
        <obo:IAO_0000116>withdrawn</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Fecundin</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.journals.elsevierhealth.com/periodicals/anirep/article/PII0378432093901125/abstract</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0001080"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fecundin vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001111 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001111">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001115"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001111</metadata:prefixIRI>
        <obo:IAO_0000115>A poxvirus vaccine vector that uses an attenuated lumpy skin disease virus as the vector.  </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>LSDV vaccine vector</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>lumpy skin disease virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 59509</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001112 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001112">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001112</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a bovine parainfluenza virus strain as vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 22570186; PMID: 24478424.</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>bovine parainfluenza virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11215</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001113 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001113">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001125"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5804"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000964"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001113</metadata:prefixIRI>
        <obo:IAO_0000116>Gametocyte antigen(s); transmission blocking through maternal antibody transfer</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>CoxAbic</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=436</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>436</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5804"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CoxAbic vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001114 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001114">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000587"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_521"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001114</metadata:prefixIRI>
        <obo:IAO_0000115>Bordetella bacterial vaccine against infection of B. avium</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_521"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella avium vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001115 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001115">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000447"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001115</metadata:prefixIRI>
        <obo:IAO_0000115>a poxvirus vaccine vector that uses an attenuated capripoxvirus strain as the vaccine vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>capripoxvirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10265</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001116 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001116">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001116</metadata:prefixIRI>
        <obo:IAO_0000115>Survival of live vaccine inside host is a process that represents the survival of a live vaccine inside its host. The time of the survival is often important for the success of the live vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>survival of live vaccine inside host</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001117 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001117">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001117</metadata:prefixIRI>
        <obo:IAO_0000115>Persistence of vaccine induced immune response is a processual entity that indicates the persistence of an immune reponse induced by a vaccine in a vaccinated host.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>persistence of vaccine induced immune response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001118 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001118">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000166"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001118</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine vector that uses a Corynebacterium pseudotuberculosis strain as the vaccine vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Corynebacterium pseudotuberculosis vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 1719</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000643"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001065"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001120</metadata:prefixIRI>
        <obo:IAO_0000116>Killed tachyzoites, reduces abortion</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Bovilis Neoguard</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=431</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>431</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovilis Neoguard vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001121">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000610"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001121</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a rhabdovirus-based viral strain as the vaccine vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>rhabdovirus-based vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11270</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001122 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001122">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001141"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001122</metadata:prefixIRI>
        <obo:IAO_0000115>a recombinant vaccine vector that uses Saccharomyces cerevisiae as the vaccine vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Saccharomyces cerevisiae vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 4932</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001123 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001123">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000649"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012180"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001123</metadata:prefixIRI>
        <obo:IAO_0000116>Modified live virus</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>RECOMBITEK Canine Parvo</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=406</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0001818>406</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RECOMBITEK Canine Parvo vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001124 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001124">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000144"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001124</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine vector that uses a Venezuelan equine encephalitis virus strain as the vaccine vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>Venezuelan equine encephalitis virus vaccine vector</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>VEE vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 11036</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001125 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001125">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5804"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000906"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5804"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001125</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5804"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria maxima vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001126 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001126">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000556"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000531"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197911"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000971"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001126</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=753</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm192126.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010394"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/VO_0000912"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>753</obo:VO_0001818>
        <obo:VO_0003099>Agriflu</obo:VO_0003099>
        <obo:VO_0003160>Active immunization of adults 18 years of age and older against influenza disease caused by influenza virus subtypes A and type B present in the vaccine.</obo:VO_0003160>
        <obo:VO_0003162>BL 125297/32</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197911"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Agriflu</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001127 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001127">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000025"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000025"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001127</metadata:prefixIRI>
        <obo:IAO_0000115>live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated Brucella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001128 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001128">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001043"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001128</metadata:prefixIRI>
        <obo:IAO_0000115>a canarypox vaccine vector that uses an attenuated canarypox virus strain ALVAC. The ALVAC vector is a canarypox virus clone obtained after four rounds of plaque purification of a strain from a vaccine for canaries. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Shunzhou Deng</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/pubmed/17227690</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>ALVAC vaccine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001129 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001129">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001129</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that is not able to replicate.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>non-replicating adenovirus accine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001130 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001130">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001130</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine against A. pleuropneumoniae infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Actinobacillus pleuropneumoniae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001131 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001131">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001131</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that is able to replicate.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>replicating adenovirus accine vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001132 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001132">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000242"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001132</metadata:prefixIRI>
        <obo:IAO_0000115>assay of CFU reduction in liver is a CFU reduction assay that is measured using the extracted liver as the tissue for isolation of infected pathogens.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>assay of CFU reduction in liver</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001133 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001133">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000242"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001133</metadata:prefixIRI>
        <obo:IAO_0000115>assay of CFU reduction in lung is a CFU reduction assay that is measured using the extracted lung as the tissue for isolation of infected pathogens.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>assay of CFU reduction in lung</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001134 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001134">
        <owl:equivalentClass>
            <owl:Class>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000108"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000108"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001127"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001134</metadata:prefixIRI>
        <obo:IAO_0000115>live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella abortus infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated Brucella abortus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001135 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001135">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000709"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000709"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001127"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001135</metadata:prefixIRI>
        <obo:IAO_0000115>live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella melitensis infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated Brucella melitensis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001136 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001136">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000721"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000721"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001127"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001136</metadata:prefixIRI>
        <obo:IAO_0000115>live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella suis infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated Brucella suis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001137 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001137">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000906"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001137</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria tenella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001138 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001138">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001476"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001138</metadata:prefixIRI>
        <obo:IAO_0000116>S48 strain with a lost ability to form cysts after passages in mice</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Ovilis Toxovax</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=429</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <obo:VO_0001818>429</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ovilis Toxovax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001139 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001139">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000169"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001139</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine viability is a viability of a vaccine organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccine organism viability</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001140 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001140">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000752"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001140</metadata:prefixIRI>
        <obo:IAO_0000116>DNA vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>West Nile-Innovator DNA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=395</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>395</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>West Nile-Innovator DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001141 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001141">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000599"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001141</metadata:prefixIRI>
        <obo:IAO_0000115>a recombinant vaccine vector that uses a fungus as the vaccine vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>fungal vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 4751</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001142 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001142">
        <owl:equivalentClass>
            <owl:Class>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                    </owl:Restriction>
                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000762"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001142</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001143 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001143">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000447"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001143</metadata:prefixIRI>
        <obo:IAO_0000115>a poxvirus vaccine vector that uses an avipox virus as the vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Avipox virus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10260</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001144 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001144">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001226"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001144</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>pCIBLSOmp31</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17600596</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=139</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>139</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella DNA vaccine encoding chimera BLSOmp31</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001145 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001145">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001139"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001145</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine being viable is a vaccine viability that indicates a vaccine uses live organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccine organism live</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000447"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001146</metadata:prefixIRI>
        <obo:IAO_0000115>a poxvirus vaccine vector that uses an orthopox virus as the vector</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Orthopoxvirus vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 10242</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001147 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001147">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001353"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001147</metadata:prefixIRI>
        <obo:IAO_0000115>A cytokine vaccine adjuvant that contains IL-12.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>IL-12 vacince adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001148 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001148">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000247"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001148</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>no vaccine protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001149 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001149">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000247"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001149</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>significant vaccine protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000247"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001150</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>enhanced significant protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001151 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001151">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                    <owl:Restriction>
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                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1238"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001151</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Piscirickettsia salmonis infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1238"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Piscirickettsia salmonis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001152 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001152">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001152</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli vaccine against enterotoxigenic E. coli infections</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>ETEC vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>enterotoxigenic E. coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001153 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001153">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000372"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001080"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001153</metadata:prefixIRI>
        <obo:IAO_0000116>Increased ovulation/twinning</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Androvax</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0001080"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Androvax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001154 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001154">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000323"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001154</metadata:prefixIRI>
        <obo:IAO_0000115>B. abortus L7/L12 is a B. abortus subunit vaccine using L7/L12 that is formed by recombinant Human Serum Albumin (HAS)-L7/L12 fusion protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus HSA-L7/L12</obo:IAO_0000118>
        <obo:IAO_0000118>Brucella abortus Human serum albumin (HAS)-L7/L12</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:19293473</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus HSA-L7/L12 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001155 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001155">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001155</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli vaccine against Shiga toxin-producing E. coli (STEC) infections</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>STEC vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238053/</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>shiga toxin-producing E. coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001156 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001156">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001461"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001156</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine against avian pathogenic Escherichia coli (APEC) infection, a major problem for the poultry industry in the world.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>APEC vaccine</obo:IAO_0000118>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian pathogenic E. coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001157 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001157">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001157</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>an E. coli vaccine against O157 E. coli strain infections</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli O157 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001158 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001158">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001158</metadata:prefixIRI>
        <obo:IAO_0000116>Extracted ApxI, ApxII, ApxIII, and outer membrane proteins</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Porcilis APP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=422</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>422</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcilis APP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001159 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001159">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001159</metadata:prefixIRI>
        <obo:IAO_0000115>PUREVAX Ferret Distemper is a lyophilized ferret vaccine of a recombinant canarypox vector expressing the HA and F glycoproteins of canine distemper virus.</obo:IAO_0000115>
        <obo:IAO_0000116>Canarypox virus-vectored vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>PUREVAX Ferret Distemper</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=409</obo:IAO_0000119>
        <obo:IAO_0000119>http://www.drugs.com/vet/purevax-ferret-distemper.html</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9669"/>
        <obo:VO_0001818>409</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PUREVAX Ferret Distemper vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001160 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001160">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001160</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccination dose specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001161 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001161">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000969"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001161</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000712"/>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>challenge dose specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001162">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001162</metadata:prefixIRI>
        <obo:IAO_0000115>specification of time interval after vaccination for challenge is a plan specification that specifies the time interval after vacciation for challenge</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>specification of vaccination-challenge interval</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001163 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001163">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000272"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001163</metadata:prefixIRI>
        <obo:IAO_0000115>pathogen challenge protocol is a protocol that is used for a pathogen challenge process.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>pathogen challenge protocol</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001164 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001164">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000555"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001164</metadata:prefixIRI>
        <obo:IAO_0000115>A titer measurement of viable bacterial or fungal numbers. It equals to a reduction of a CFU count from another CFU count. This term is often used as a measurement of a vaccine protection study.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>reduction of colony forming unit</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001165 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001165">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000712"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001165</metadata:prefixIRI>
        <obo:IAO_0000115>intraperitoneal pathogen challenge is a pathogen challenge process that occurs in the intraperitoneal site of a host.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>intraperitoneal pathogen challenge</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001166 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001166">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001166</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000344"/>
        <obo:IAO_0000115>a vaccination process that occurs in the intraperitoneal route</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>intraperitoneal vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001167 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001167">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001167</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>KLH-s-FimH1-25 with CFA and then IFA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4329</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>4329</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>KLH-s-FimH1-25 with CFA and then IFA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001168 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001168</metadata:prefixIRI>
        <obo:IAO_0000115>an E. coli subunit vaccine that uses E. coli FimH adhesin protein as teh antigen, and uses the complete Freund&apos;s adjuvant (CFA) in the first vaccination and the incomplete Freund&apos;s adjuvant (IFA) in the boost vaccination.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. coli FimH with CFA and then IFA</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: http://www.ncbi.nlm.nih.gov/pubmed/9110982</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4330</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010987"/>
        <obo:VO_0001818>4330</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli FimH with CFA and then IFA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001169 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001169</metadata:prefixIRI>
        <obo:IAO_0000115>E. coli DNA vaccine is a DNA vaccine that protects against an E. coli infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001170 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001170">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000506"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001170</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine organism that is a specific strain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001182"/>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>vaccine strain</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001171 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001171">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001171</metadata:prefixIRI>
        <obo:IAO_0000115>B. melitensis bp26 and omp31 deletion vaccine is a Brucella melitensis vaccine that has double deletions of bp26 and omp31.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis Rev. 1 with bp26 and omp31 deletions</obo:IAO_0000118>
        <obo:IAO_0000118>CGV2631</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17070627</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=779</obo:IAO_0000119>
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        <obo:VO_0001818>779</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis Rev. 1 with bp26 and omp31 deletions vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001172 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001172</metadata:prefixIRI>
        <obo:IAO_0000115>pCIOmp31 is a B. melitensis DNA vaccine expressing Omp31 that uses the pCI plasmid.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>pCIOmp31</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16177328</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pCIOmp31 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001173 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001173">
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001173</metadata:prefixIRI>
        <obo:IAO_0000115>pTargeTomp31 is a B. melitensis DNA vaccine expressing Omp31  that uses the pTargeT mammalian expression system vector (Promega, USA).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>pTargeTomp31</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17014873</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pTargeTomp31 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001175 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001175">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000323"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001175</metadata:prefixIRI>
        <obo:IAO_0000115>B. abortus L7/L12 fused to MBP is a B. abortus subunit vaccine using L7/L12 that uses recombinant L7/L12 fused on maltose binding protein MBP.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus L7/L12 fused to MBP</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:8873388</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus L7/L12 fused to MBP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001176 -->

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                    </owl:Restriction>
                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001176</metadata:prefixIRI>
        <obo:IAO_0000115>inactivated influenza vaccine is an inactivated viral vaccine that targets at influenza viral infections.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001177 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001177">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000846"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001177</metadata:prefixIRI>
        <obo:IAO_0000116>Precocious and egg-passaged lines</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Livacox</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=426</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>426</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Livacox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001178">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001178</metadata:prefixIRI>
        <obo:IAO_0000115>live attenuated influenza vaccine is a live attenuated vaccine that protects against influenza viral infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001180 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001180">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001180</metadata:prefixIRI>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>laboratory test</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000949"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001181</metadata:prefixIRI>
        <obo:IAO_0000116>Live temperature-sensitive mutant strain; eye drop administration</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Vaxsafe MG</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=419</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>419</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaxsafe MG vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001182</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine role that is borne by an organism strain serving as a vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine strain role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001183 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001183">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000655"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000759"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001183</metadata:prefixIRI>
        <obo:IAO_0000116>Peptide conjugated to keyhole limpet hemocyanin in mycobacterium-oil adjuvant (AdjuVac); contraceptive vaccine to control wildlife</obo:IAO_0000116>
        <obo:IAO_0000116>registration reported to be in progress</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>GonaCon</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.aphis.usda.gov/wildlife_damage/nwrc/research/reproductive_control/gonacon.shtml</obo:IAO_0000119>
        <obo:IAO_0000119>a contraceptive vaccine that is used in wildlife population</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000972"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9850"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9900"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>GonaCon vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001184">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0200201"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001184</metadata:prefixIRI>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine protection ANOVA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001185">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000906"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001185</metadata:prefixIRI>
        <obo:IAO_0000116>In ovo delivery using proprietary platform injection system</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=425</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>425</obo:VO_0001818>
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        <rdfs:label>Inovocox vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001186 -->

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        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0001203"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0001204"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0001205"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0001206"/>
        <obo:IAO_0000115>A data set that represents a set of data for a list of variables (e.g., vaccination dose) for the data analysis of an vaccine investigation study.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine investigation data set</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001187 -->

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        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:IAO_0000115>a vaccination that occurs in the intramuscular route.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>intramuscular vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001188 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001188">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001188</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents a vaccine strain. Different strains can be represented using distinct digital numbers. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine strain datum</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001189 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001189">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001189</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents vaccine viability. 0 = live; 1 = irradiated; 2 = killed.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine viability datum</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001190 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001190</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that indicates the usage of a vaccine adjuvant. Different digital numbers can be used to represent different adjuvants. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine adjuvant usage datum</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001191 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001191">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
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        <obo:IAO_0000115>A measurement datum that represents a specific protective antigen used in a vaccine. The antigen can be represented by a described digit. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine protective antigen datum</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001192">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001192</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents a specific mutated gene from a vaccine strain. The mutated can be represented by a described digit. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>mutated gene in vaccine strain datum</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001193 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001193">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001193</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents a specific mouse strain used for vaccination. Different strains can be represented using discretized digitals.  For example, 0 = BALB/c; 1 = CD1; 2 = mixed/outbred; 3 = C57BL/6; 4 = OF1; 5 = 129/Sv; 6 = Swiss albino.
</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccination mouse strain datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001194">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001194</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents the biological sex of an animal. The result can be represented using a discretized digit, for example, 0 = female; 1 = male.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <obo:IAO_0000136 rdf:resource="http://purl.obolibrary.org/obo/PATO_0000047"/>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>biological sex datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001195 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001195">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001195</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents a specific route (e.g., i.p.) used for vaccination. Different routes can be represented using discretized digitals.  0 = IP; 1 = PO; 2 = SC; 3 = IM; 4 = IN; 6 = IG; 7 = IV; 8 = ID.

</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccination route datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001196 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001196">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000814"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001196</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccination dose that is used with the unit of colony forming units (CFU).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccination dose (unit: CFU)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001197 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001197">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004926"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001197</metadata:prefixIRI>
        <obo:IAO_0000115>An age range at vaccination that represents the animal age (unit: day) at the time of vaccination.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>animal age at vaccination in days</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001198 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001198">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001198</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents a specific pathogen strain used for animal challenge study. Different pathogen strains can be represented using discretized digitals.  </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>pathogen strain for challenge datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001199 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001199">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001199</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents a specific pathogen used for animal challenge study. Different pathogens can be represented using discretized digitals.  </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>pathogen challenge datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001200 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001200">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000649"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001200</metadata:prefixIRI>
        <obo:IAO_0000116>Native fucose-mannose-ligand antigen complex</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Leishmune</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=435</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0001818>435</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmune vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001201 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001201">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001105"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001201</metadata:prefixIRI>
        <obo:IAO_0000116>Live oral vaccine</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Enterisol Ileitis</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=411</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>411</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29546"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Enterisol Ileitis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001202 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001202">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000900"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001202</metadata:prefixIRI>
        <obo:IAO_0000115>A challenge dose that is represented with the unit of colony forming units (CFU).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>challenge dose (unit: CFU)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001203 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001203">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001203</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents a length of days as the interval between a vaccination and a challenge in a specific vaccine protection study. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccination-challenge interval in days</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001204 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001204">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000189"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001204</metadata:prefixIRI>
        <obo:IAO_0000115>A colony forming unit (CFU) from the sample of mouse spleen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>CFU per spleen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001205 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001205">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001164"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001205</metadata:prefixIRI>
        <obo:IAO_0000115>A reduction of colony forming unit that was measured with the unit of colony forming units (CFU) from the sample of mouse spleen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>CFU reduction per spleen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001206 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001206">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001206</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that represents a type of vaccine protection efficacy as an outcome of a vaccine protection study. The result can be represented as a digit, for example, 0 = no protection, and 1 = protection (determined by a p-value cutoff).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf</obo:IAO_0000119>
        <obo:IAO_0000119>Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. </obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine protection efficacy datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001207 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001207">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000573"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001207</metadata:prefixIRI>
        <obo:IAO_0000115>A Chlamydia bacterial vaccine against Chlamydia trachomatis infection</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_813"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia trachomatis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001208 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001208">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000323"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001208</metadata:prefixIRI>
        <obo:IAO_0000115>B. abortus BLS-L7/L12 is a B. abortus subunit vaccine using L7/L12 that is made as a recombinant BLS-L7/L12 fusion protein vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus BLS-L7/L12</obo:IAO_0000118>
        <obo:IAO_0000118>recombinant Brucella BLS-L7/L12 fusion protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>recombinant Brucella lumazine synthase and L7/L12 fusion protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:19596411</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus BLS-L7/L12 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001209 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001209">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001209</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine protection efficacy measurement is an assay that measures the protection efficayc of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>vaccine protection efficacy measurement</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001210 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001210</metadata:prefixIRI>
        <obo:IAO_0000115>a subunit vaccien that uses LPS as protective antigen</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>lipopolysaccharide subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001211 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001211">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10497"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001211</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against African swine fever virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10497"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>African swine fever virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001213 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001213">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12110"/>
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                </owl:intersectionOf>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000646"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12110"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001213</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Foot-and-mouth disease virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12110"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Foot-and-mouth disease virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001214 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001214">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
                    </owl:Restriction>
                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000315"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001214</metadata:prefixIRI>
        <obo:IAO_0000115>Bacterial vaccine that uses inactivated bacterial organism. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated bacterial vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001215 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001215">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000643"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000972"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001215</metadata:prefixIRI>
        <obo:IAO_0000115>an anti-reproductive vaccine for cattle. The vaccine is based on the established principle that antibodies to the hypothalamic releasing hormone, gonadotrophin releasing hormone (GnRH) block the action of GnRH on pituitary secretion of luteinizing hormone and follicle stimulating hormone, leading to gonadal atrophy in mammals. The vaccine comprises an immunogenic GnRH:ovalbumin conjugate formulated in a novel double adjuvant system and is administered in a two-dose treatment regimen. </obo:IAO_0000115>
        <obo:IAO_0000116>LHRH peptide conjugated to ovalbumin; oil emulsion adjuvant</obo:IAO_0000116>
        <obo:IAO_0000116>withdrawn in 1996</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Vaxstrate</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.ncbi.nlm.nih.gov/pubmed/1370000</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000972"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaxstrate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001216 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001216">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001216</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Lymphocytic choriomeningitis mammarenavirus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0003044"/>
        <rdfs:label>obsolete Lymphocytic choriomeningitis mammarenavirus vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001217 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001217">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001217</metadata:prefixIRI>
        <obo:IAO_0000115>Bacterial vaccine that is live and attenuated.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated bacterial vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001218 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001218">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001218</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that is used for animals (excluding humans), for example, pet, domestic, wildlife, and livestock animals.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>veterinary vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001220 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001220">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001220</metadata:prefixIRI>
        <obo:IAO_0000115>a viral vaccine that is live attenuated</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated viral vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001221 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001221">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000108"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001221</metadata:prefixIRI>
        <obo:IAO_0000115>a B. abortus vaccine that uses subunit antigen</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001222 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001222">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001468"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001222</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects aganist Newcastle disease virus infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle disease virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001223 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001223">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000709"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001223</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001224">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11287"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001224</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Viral hemorrhagic septicemia virus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11287"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Viral hemorrhagic septicemia virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001225 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001225">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000108"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000108"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001225</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001226 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001226">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000709"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001226</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001227 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001227">
        <owl:equivalentClass>
            <owl:Class>
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                    <owl:Restriction>
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                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000727"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001227</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Human herpesvirus 5.</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10359"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human betaherpesvirus 5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001228 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001228">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                    <owl:Restriction>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12066"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003547"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12066"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001228</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Coxsackievirus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12066"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coxsackievirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001229">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003047"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001229</metadata:prefixIRI>
        <obo:IAO_0000115>A protozoan vaccine that protects against infection with Schistosoma japonicum</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Schistosoma japonicum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001230 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001230">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_160"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003494"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_160"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001230</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Treponema pallidum infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_160"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Treponema pallidum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001231 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001231">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000762"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001231</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Leishmania major.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania major vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001232">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110034"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001232</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>protective antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001233 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001233">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001233</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a viral vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>viral vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001234">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001234</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a protozoan vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>protozoan vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001235 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001235">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000267"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001235</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a fungal vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000267"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>fungal vaccine preparation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001236">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003495"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001236</metadata:prefixIRI>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>trivalent influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001237 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001237">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001237</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant compsed of CpG DNA.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:12899580</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>CpG DNA vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001238 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001238">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001238</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant that is a stable oil-in-water emulsion.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&amp;N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&amp;N4=M6661%7CSIGMA&amp;N25=0&amp;QS=ON&amp;F=SPEC</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Ribi vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001239 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001239">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001239</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant named RC529 that is a lipid A mimetic.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16204643</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>RC529 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001240 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001240">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000884"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001240</metadata:prefixIRI>
        <obo:IAO_0000115>An aluminum vaccine adjuvant that is aluminum potassium sulfate (AlK(SO4)2).</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>aluminum potassium sulfate adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000127"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001241</metadata:prefixIRI>
        <obo:IAO_0000115>An aluminum hydroxide vaccine adjuvant that is a gel that is made by precipitation of aluminum hydroxide Al(OH)3 under alkaline conditions.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Alhydrogel</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Alhydrogel vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001348"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001242</metadata:prefixIRI>
        <obo:IAO_0000115>A cholera toxin derived vaccine adjuvant made of the B subunit of the cholera toxin from Vibrio cholerae.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>CTB</obo:IAO_0000118>
        <obo:IAO_0000118>cholera toxin B</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>cholera toxin B subunit vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001244">
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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1115</obo:IAO_0000119>
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        <obo:VO_0001818>1115</obo:VO_0001818>
        <obo:VO_0003099>Prevnar 13</obo:VO_0003099>
        <obo:VO_0003160>- Active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F in children 6 weeks through 5 years of age (prior to the 6th birthday).
- Active immunization for the prevention of otitis media caused by S. pneumoniae serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F. No otitis media efficacy data are available for serotypes 1, 3, 5, 6A, 7F, and 19A In children 6 weeks through 5 years of age (prior to the 6th birthday).
- Active immunization for the prevention of invasive disease caused by S. pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F in children 6 years through 17 years of age (prior to the 18th birthday). 
- Active immunization for the prevention of pneumonia and invasive disease caused by S. pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F in adults 18 years of age and older.
- Limitations: Prevnar 13 does not protect against disease caused by S. pneumoniae serotypes that are not in the vaccine.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM574852.pdf</obo:VO_0003161>
        <obo:VO_0003162>125324</obo:VO_0003162>
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        <obo:IAO_0000115>SYNFLORIX is indicated for active immunization of infants and children from 6 weeks up to 5 years of age against Streptococcus pneumoniae serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F and 23F and invasive disease caused by these serotypes (including sepsis, meningitis, bacteraemic pneumonia, pleural empyema and bacteraemia).</obo:IAO_0000115>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm201342.htm</obo:IAO_0000119>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>1113</obo:VO_0001818>
        <obo:VO_0003099>Menveo</obo:VO_0003099>
        <obo:VO_0003160>For active immunization to prevent invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, Y and W-135 when administered to individuals 2 months to 55 years of age.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM201349.pdf</obo:VO_0003161>
        <obo:VO_0003162>125300</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Menveo vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001247 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001247</metadata:prefixIRI>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Arepanrix H1N1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1116</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>1116</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Arepanrix H1N1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001248 -->

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        <owl:equivalentClass>
            <owl:Class>
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                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0021066"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001248</metadata:prefixIRI>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1117</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1117</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Intanza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001249 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001249">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001249</metadata:prefixIRI>
        <obo:IAO_0000115>An aqueous formula of the synthetic vaccine adjuvant RC529.</obo:IAO_0000115>
        <obo:IAO_0000116>RC529-AF can be obtained from Corixa Corporation (Seattle, WA).</obo:IAO_0000116>
        <obo:IAO_0000118>RC529 vaccine adjuvant in an aqueour formulation</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 15308371</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>RC529-AF vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001250">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001250</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant derived from the lipopolysaccharide (LPS) of Salmonella minnesota R595.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>3-O-deacylated monophosphoryl lipid A vaccine adjuvant</obo:IAO_0000118>
        <obo:IAO_0000118>3D-MLA</obo:IAO_0000118>
        <obo:IAO_0000118>MPL vaccine adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10768940</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.frontiersin.org/articles/10.3389/fimmu.2020.577823</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>monophosphoryl lipid A vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001251 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001251">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000388"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001251</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli LT toxin derived vaccine adjuvant that is a mutant form of LT containing a Ser-Lys substitution in position 63 which has been shown to be totally devoid of toxicity stable to protease treatment and able to act as mucosal adjuvant.</obo:IAO_0000115>
        <obo:IAO_0000116>LTK63 is an enzymatically inactive mutant of the heat-labile enterotoxin of Escherichia coli. It can be used as a potent mucosal adjuvant.</obo:IAO_0000116>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:10790422</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:17920733</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9607006</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>LTK63 vaccine mutant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001252 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001252">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000047"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001252</metadata:prefixIRI>
        <obo:IAO_0000115>is a bacterial toxin (usually an exotoxin) whose toxicity has been weakened or suppressed either by chemical (formalin) or heat treatment, while other properties, typically immunogenicity, are maintained.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Toxoid</obo:IAO_0000119>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001253 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001253">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001253</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>capsular polysaccharide subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001254 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001254">
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>capsular polysaccharide of pathogen organism as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001255">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001255</metadata:prefixIRI>
        <obo:IAO_0000115>a subunit vaccine that uses polysaccharide as protective antigen</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>polysaccharide subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001256 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001256">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000000"/>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>polysaccharide of pathogen organism as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001257 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001257">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001257</metadata:prefixIRI>
        <obo:IAO_0000115>The specification of an objective to prevent a disorder.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>prevention of disorder objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001258 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001258">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001258</metadata:prefixIRI>
        <obo:IAO_0000115>The specification of an objective to ameliorate  a disorder.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>amelioration of disorder objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001259 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001259">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001259</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant derived from heat-killed Corynebacterium parvum.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:4596278</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:5483667</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7591056</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>killed Corynebacterium parvum vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001260 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001260">
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        <obo:IAO_0000115>An emulsion vaccine adjuvant which is a water-in-oil adjuvant with CRL-8300 (a block copolymer), squalene, and sorbitan monooleate.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Titermax Gold</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Titermax Gold vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001261">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001261</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is dimethyldioctadecylammonium bromide (DDA), a lipophilic quaternary ammonium salt known as a good adjuvant when co-administered systemically or nasally with an antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Dimethyl dioctadecyl ammonium bromide</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:1439129</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>DDA vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001262 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001262">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000366"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001262</metadata:prefixIRI>
        <obo:IAO_0000115>A liposome-based vaccine adjuvant that have a positive surface charge.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:19874860</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>cationic liposomal vaccine adjuvant DDA:TDB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001263 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001263">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001358"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001263</metadata:prefixIRI>
        <obo:IAO_0000115>A tenosactive compound vaccine adjuvant that contains purified extract from the bark of the South American tree Quillaja saponaria Molina.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>QuilA vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001264 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001264">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001264</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant comprised of monophosphoryl lipid A (MPL), QS21 and an oil in water emulsion.</obo:IAO_0000115>
        <obo:IAO_0000116>monophosphoryl lipid A (MPL), QS21 and an oil in water emulsion.</obo:IAO_0000116>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15187142</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:15780441</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>AS02 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001265 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001265">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001354"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001265</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant that is a combination of 50 ug of the immunoenhancer MPL (3-O-desacyl-4′-monophosphoryl lipid A) with 500 ug of aluminium salt.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:21527299</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>AS04 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001266 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001266">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001266</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant which is an emulsion plus DDA.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Emulsigen D</obo:IAO_0000118>
        <obo:IAO_0000118>VSA-3</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16187717</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>VSA-3 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001267 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001267">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001358"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001267</metadata:prefixIRI>
        <obo:IAO_0000115>A tensoactive compound vaccine adjuvant that is derived from saponin, a compound that is an immunostimulator found in the plant P. senega.</obo:IAO_0000115>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>saponin vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001268 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001268">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001271"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001268</metadata:prefixIRI>
        <obo:IAO_0000115>A Montanide vaccine adjuvant that is formulated as water-in-oil emulsions and induces high antibody titers in several animal species. It is a vaccine adjuvant composed of metabolizable oil and a surfactant system designed to make a water-in-oil emulsion. It has been used since 1992 in more than 50 clinical trials related to therapeutic vaccines against various diseases such as cancer and malaria.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Montanide ISA 720</obo:IAO_0000118>
        <obo:IAO_0000118>Montanide ISA 720 VG</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15752840</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://www.seppic.com/human-health/vaccine-adjuvant/montanide-isa-720-@/view-1044-seproduit.html?menuid=,979,&amp;lang=en</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Montanide ISA 720 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001269 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001269">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001271"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001269</metadata:prefixIRI>
        <obo:IAO_0000115>A Montanide vaccine adjuvant that is a mineral oil adjuvant.</obo:IAO_0000115>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Montanide incomplete Seppic adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001270 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001270">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001271"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001270</metadata:prefixIRI>
        <obo:IAO_0000115>A Montanide vaccine adjuvant that is a vaccine adjuvant composed of a light mineral oil and a surfactant system designed to make a water-in-oil emulsion.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Montanide ISA51</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.seppic.com/human-health/vaccine-adjuvant/montanide-isa-51-@/view-1042-seproduit.html?menuid=,979,&amp;lang=en</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Montanide ISA51 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001271 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001271">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001271</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant developed by Montanide.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.montanide.com/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Montanide vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001272">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000388"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001272</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli LT toxin derived vaccine adjuvant composed of the B subunit of E. coli heat-labile toxin.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>B subunit of E. coli heat-labile enterotoxin</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>EtxB vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001273">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001273</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant with the tradename Polygen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>URL: http://www.mvp-technologies.com/adjuvants/Polygen%20Final%20Technical%20Bulletin.pdf</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Polygen vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001274 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001274">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000444"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000490"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001274</metadata:prefixIRI>
        <obo:BFO_0000054 rdf:resource="http://purl.obolibrary.org/obo/VO_0000490"/>
        <obo:IAO_0000115>Role that inheres in an organism that is the target of a vaccine administration (vaccination process).</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/677</obo:IAO_0000233>
        <obo:RO_0000052 rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine recipient role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001275 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001275">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001275</metadata:prefixIRI>
        <obo:IAO_0000115>A role that represents a target (i.e., some disorder) of immunization.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>immunization target role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001276 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001276">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000494"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001276</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>bacterial vaccine immunization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001277 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001277">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000494"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001277</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>viral vaccine immunization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001278">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000494"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001278</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>cancer vaccine immunization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001279 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001279">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000494"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001279</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>parasite vaccine immunization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001280">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001280</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete immunization target role of pathogen</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001281">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001281</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete immunization target role of bacterial pathogen</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001282 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001282">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001282</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete immunization target role of viral pathogen</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001283 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001283">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001283</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete immunization target role of parasite pathogen</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001284 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001284">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001284</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete immunization target role of fungal pathogen</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001285 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001285">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001359"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001285</metadata:prefixIRI>
        <obo:IAO_0000115>A carbohydrate vaccine adjuvant, which enhances both humoral and cell-mediated immunity to oligopeptides in experimental animal models.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Algal Glucan vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001286 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001286">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001354"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001286</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant that suspension of 1-2um ovoids of immune stimulant gamma inulin (g-IN) in which alum is embedded as a carrier for protein or other anionic antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:1887671</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Algammulin vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001287 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001287">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001287</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is Bay R1005 (N-(2-Deoxy-2-L-leucylamino beta-D-glucopyranosyl)-N-octadecyldodecanoylamide hydroacetate ).</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>BAY R1005</obo:IAO_0000118>
        <obo:IAO_0000118>N-( 2-Deoxy-2-L-leucylamino-β-D-glucopyranosyl)-N-octadecyldodecanoylamide hydroacetate</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>BAY R1005 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001288 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001288">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001288</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is N, N-dioctadecyl-N&apos;, N&apos;-bis(2-hydroxyethyl) propanediamine (Avridine).</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Avridine</obo:IAO_0000118>
        <obo:IAO_0000118>CP20,96</obo:IAO_0000118>
        <obo:IAO_0000118>N, N-dioctadecyl-N&apos;, N&apos;-bis( 2-hydroxyethyl) propanediamine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Avridine vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001289 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001289">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000131"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001289</metadata:prefixIRI>
        <obo:IAO_0000115>A calcium phosphate vaccine adjuvant that is a gel prepared by precipitating soluable calcium and phosphate salts.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>calcium phosphate gel</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>calcium phosphate gel vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001290 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001290">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001290</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant composed of the CTA1-DD fusion protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>CTA1-DD gene fusion protein</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>cholera toxin A1-subunit-ProteinA D-fragment fusion protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001291 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001291">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000093"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001291</metadata:prefixIRI>
        <obo:IAO_0000115>A mineral salt vaccine adjuvant that is composed of Deoxycholic acid sodium salt (DOC) complexed with aluminum hydroxide.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>DOC/Alum Complex</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>DOC/Alum Complex vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001292">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001359"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001292</metadata:prefixIRI>
        <obo:IAO_0000115>A carbohydrate adjuvant that is a highly specific activator of the alternative pathway of complement in vitro and in vivo, and is composed of linear (unbranched) b-D-(2-1) polyfructofuranosyl-a-D-glucose.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:3265692</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>gamma Inulin vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001293 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001293">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001354"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001293</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant that is comprised of a mixture of GMDP, DDA, and Zinc L-proline salt complex (ZnPro8).</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15953835</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Gerbu vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001294 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001294">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001353"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001294</metadata:prefixIRI>
        <obo:IAO_0000115>A cytokine vaccine adjuvant that includes GM-CSF.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>GM-CSF vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001295 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001295">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001295</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant containing GMDP, a higly effective primary adjuvant.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>GMDP</obo:IAO_0000118>
        <obo:IAO_0000118>N-acetylglucosaminyl-(b1-4)-N-acetylmuramyl-L-alanyl-D-isoglutamine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>GMDP vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001296 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001296">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001360"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001296</metadata:prefixIRI>
        <obo:IAO_0000115>An IFN-gamma vaccine adjuvant that is composed of recombinant hIFN-gamma.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>recombinant hIFN-gamma/Interferon-g vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001297 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001297">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001353"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001297</metadata:prefixIRI>
        <obo:IAO_0000115>A cytokine vaccine adjuvant that includes IL-1b.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>interleukin-1b vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001298 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001298">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001353"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001298</metadata:prefixIRI>
        <obo:IAO_0000115>A cytokine vaccine adjuvant that includes IL-2.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>IL-2 vaccine adjuvant</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>interleukin-2 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001299 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001299">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001353"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001299</metadata:prefixIRI>
        <obo:IAO_0000115>A cytokine vaccine adjuvant that includes IL-7.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>IL-7 vaccine adjuvant</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>interleukin-7 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001300 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001300">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001300</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that includes loxoribine which is a guanosine analog derivatized at position N7 and C8, and activates TLR-7.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>7-allyl-8-oxoguanosine</obo:IAO_0000118>
        <obo:IAO_0000118>Loxoribine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Loxoribine vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001301 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001301">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001301</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant consisting of an oil (squalene)-in-water nano emulsion.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>MF59</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:20488726</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>MF59 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001302 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001302">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000366"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001302</metadata:prefixIRI>
        <obo:IAO_0000115>A liposome-based vaccine adjuvant that consists of liposomes containing  the synthetic lipophilic analog of muramyl dipeptide, muramyl tripeptide phosphatidylethanolamine (MTP-PE).</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>MTP-PE</obo:IAO_0000118>
        <obo:IAO_0000118>MTP-PE Liposomes</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:1431559</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>MTP-PE Liposomes vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001303 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001303">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001303</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant made of murametide that has adjuvant activity similar to MDP.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Murametide</obo:IAO_0000118>
        <obo:IAO_0000118>Nac-Mur-L-Ala-D-Gln-OCH3</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Murametide vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001304 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001304">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001304</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant called murapalmitine.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Murapalmitine</obo:IAO_0000118>
        <obo:IAO_0000118>Nac-Mur-L-Thr-D-isoGIn-sn-glyceroI dipalmitoyl</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Murapalmitine vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001305 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001305">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001305</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that includes an MDP analog called D-Murapalmitine.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>D-Murapalmitine</obo:IAO_0000118>
        <obo:IAO_0000118>Nac-Mur-D-Ala-D-isoGln-sn-glycerol dipalmitoyl</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>D-Murapalmitine vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001306 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001306">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001306</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is composed of neuraminidase-galactose oxidase (NAGO) a mixture of mixture of the two enzymes-neuraminidase and galactose oxidase.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>NAGO</obo:IAO_0000118>
        <obo:IAO_0000118>Neuraminidase-galactose oxidase</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>NAGO vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001307 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001307">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001307</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant consisting of multi-lamellar vesicles comprising a mixture of non-ionic surfactant (e.g., 1-monopalmitoyl-rac-glycerol), cholesterol and dicetyl phosphate used as a primary vaccine adjuvant for entrapped antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>NISV</obo:IAO_0000118>
        <obo:IAO_0000118>non-ionic surfactant vesicles</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>non-ionic surfactant vesicles vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001308 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001308">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001308</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant made from the emulsion polymerization of methyl methacrylate.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>PMMA</obo:IAO_0000118>
        <obo:IAO_0000118>Polymethyl methacrylate</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>PMMA vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001309 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001309">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001309</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant synthesized from stable protein phospholipid-calcium precipitates.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>protein cochleates</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>protein cochleates vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001310">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001267"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001310</metadata:prefixIRI>
        <obo:IAO_0000115>A saponin vaccine adjuvant that is composed of extracts from the bark of the Quillaja saponaria Molina tree. Specifically, it is an acylated 3, 28-bisdesmodic triterpene glycosides (1,3) or &quot;saponin&quot;  with a molecular formula of C92O46H148 and molecular weight of 1990 Da. QS-21 is one of the active fractions of the bark of Chilean tree, Quillaja saponaria, purified using a reverse-phase chromatography (RP-HPLC).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>QS-21</obo:IAO_0000118>
        <obo:IAO_0000118>Stimulon™ QS-21 Adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:27213168</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>QS-21 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001311 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001311">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000884"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001311</metadata:prefixIRI>
        <obo:IAO_0000115>An aluminum vaccine adjuvant that is a synthetic oxyhydroxide of aluminum (aluminum hydroxide) prepared by acid-base precipitation.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Rehydragel HPA</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Rehydragel HPA vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001312 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001312">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000127"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001312</metadata:prefixIRI>
        <obo:IAO_0000115>An aluminum hydroxide vaccine adjuvant that is a low visosity aluminum hydroxide gel.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Rehydragel LV</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Rehydragel LV vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001313 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001313">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001353"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001313</metadata:prefixIRI>
        <obo:IAO_0000115>A cytokine vaccine adjuvant that contains the 163-171 peptide of IL-1β.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>IL-1β 163-171 peptide vaccine adjuvant</obo:IAO_0000118>
        <obo:IAO_0000118>Sclavo peptide</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Sclavo peptide vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001314 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001314">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001314</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant that is a water-in-oil emulsion that is used as an adjuvant and has immunostimulating properties similar to Freund&apos;s complete adjuvant (FCA).</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Specol</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:1439130</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Specol vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001315 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001315">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001315</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant that is an emulsion of squalane (5%), Tween 80( 0.2%), Pluronic L121( 1.25%), phosphate-buffered saline pH 7.4, and antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>SPT (Antigen Formulation)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001316 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001316">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001316</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant stearyl tyrosine is considered an &quot;organic equivelant&quot; of aluminum hydroxide.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>stearyl tyrosine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>stearyl tyrosine vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001317 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001317">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001317</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant called Theramide that is composed of N-acetylglucosaminyl-N-acetylinuramyl-L-Ala-D-isoGlu-L-Ala-dipalmitoxy propylamide (DTP-DPP).</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Theramide</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Theramide vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001318 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001318">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001318</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is a copolymer (CRL1005), based on a 12 kDa polyoxypropylene (POP) core with 5% POE.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>CRL1005</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:10717336</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>CRL1005 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001319</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant and is made from non-toxic lipid droplets a few hundred nanometers in diameter and made from surfactants approved for human consumption and common food substances that are &apos;Generally Recognized as Safe&apos; (GRAS) by the FDA.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>http://nano.med.umich.edu/platforms/Nanoemulsions.html</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>nanoemulsion vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001320">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001320</metadata:prefixIRI>
        <obo:IAO_0000115>An emusion vaccine adjuvant that contains alpha-tocopherol and squalene, two biodegradable polyprenyls, in an oil-in-water emulsion.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>AS03</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:21256188</obo:IAO_0000119>
        <obo:VO_0005438>801</obo:VO_0005438>
        <obo:VO_1000000>AS03 Adjuvant</obo:VO_1000000>
        <obo:VO_1000001>AS03 Adjuvant</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>AS03 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001321 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001321">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001321</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli LT toxin derived vaccine adjuvant that is a mutant form of E.coli heat-labile toxin.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>LTR192G</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11803061</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>LTR192G vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001322 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001322">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001322</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant containing E. coli heat-labile toxin.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>E. coli heat-labile toxin, LT</obo:IAO_0000118>
        <obo:IAO_0000118>LT Oral Adjuvant</obo:IAO_0000118>
        <obo:IAO_0000118>LT-OA</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>E. coli heat-labile toxin vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001323 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001323">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001323</metadata:prefixIRI>
        <obo:IAO_0000115>An aluminum vaccine adjuvant that is a a proprietary aluminum hydroxyphosphate sulfate formulation that is both physically and functionally distinct from traditional aluminum phosphate and aluminum hydroxide adjuvants.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>AAHSA</obo:IAO_0000118>
        <obo:IAO_0000118>Merck Aluminum Adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17581283</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>amorphous aluminum hydroxyphosphate sulfate adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001324 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001324">
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        <obo:IAO_0000118>Matrix-S</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Matrix-S vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001325 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001325">
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        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001325</metadata:prefixIRI>
        <obo:IAO_0000118>Brucella BFR antigen vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>recombinant Brucella abortus Bfr protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11447155</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus subunit vaccine using Bfr</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001326 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001326">
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        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001326</metadata:prefixIRI>
        <obo:IAO_0000118>Brucella abortus Omp16 vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:18981242</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus subunit vaccine using Omp16</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001327 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001327">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001226"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001327</metadata:prefixIRI>
        <obo:IAO_0000118>B. melitensis DNA vaccine encoding Bp26 and Tf</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis DNA vaccine encoding Bp26 and Tf</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001328 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001328">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001328</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant contiaing imiquimod a imidazoquinoline.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>1-(2-methypropyl)-IH-imidazo[4,5-c]quinolin-4-amine</obo:IAO_0000118>
        <obo:IAO_0000118>Aldara™</obo:IAO_0000118>
        <obo:IAO_0000118>R-837</obo:IAO_0000118>
        <obo:IAO_0000118>S26308</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:18566444</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>imiquimod vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001329 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001329">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001329</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant, resiquimod is a chemical analog of imiquimod.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15068862</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>resiquimod vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001330 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001330">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001330</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant containing 2.5% squalene.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:20193791</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>AF03 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001331 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001331">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001331</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant composed of flagellin from gram-negative bacteria.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>FliC</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:16428759</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:21048152</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Flagellin vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001332</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant containing Poly(I:C), a synthetic double stranded analog of RNA.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>polyriboinosinic-polyribocytidylic acid</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Polyinosinic:polycytidylic_acid</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>poly(I:C) vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001333 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001333">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001356"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001333</metadata:prefixIRI>
        <obo:IAO_0000115>A particulate antigen delivery system vaccine adjuvant that is a vaccine adjuvant comprising cholesterol, phospholipid and saponin but without antigen.</obo:IAO_0000115>
        <obo:IAO_0000116>ISCOMATRIX is identical to ISCOMs except that it does not contain antigen. Ref: PMID: 17336431.</obo:IAO_0000116>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:19450632</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>ISCOMATRIX vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001334">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001267"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001334</metadata:prefixIRI>
        <obo:IAO_0000115>A saponin vaccine adjuvant that is made from highly purified saponins.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.isconova.com/products/abisco-research-reagent/abisco-100.aspx</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Abisco-100 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001335 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001335">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001356"/>
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        <obo:IAO_0000115>A particulate antigen delivery system vaccine adjuvant  that is albumin-heparin microparticles vaccine adjuvant that is prepared from albumin and heparin stabilized by cross-linking reaction with EDC.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16734558</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>albumin-heparin microparticles vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001336 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001336">
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        <obo:IAO_0000115>A combination vaccine adjuvant and is based on the combination of Monophosphoryl Lipid A(MPL), QS21 (a purified fraction of Saponin extracted from Quillarja Saponaria), and a proprietary oil in water emulsion.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.pasteur.fr/applications/euroconf/vaccins/vaccins-abs.html</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>AS-2 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001337 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001337">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001353"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001337</metadata:prefixIRI>
        <obo:IAO_0000115>A cytokine vaccine adjuvant that includes B7-2.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>B7-2 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001338 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001338">
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        <obo:IAO_0000115>A synthetic vaccine adjuvant that is a local anaesthetic drug belonging to the amino amide group, and is used as a vaccine adjuvant in DNA vaccines.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15246629</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: http://en.wikipedia.org/wiki/Bupivacaine</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Bupivacaine vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001339 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001339">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001339</metadata:prefixIRI>
        <obo:IAO_0000115>A liposome-based vaccine adjuvant that is composed of virus sized liposomes that contain a DNA plasmid.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>cationic liposome-DNA complex JVRS-100</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:19285425</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>cationic liposome-DNA complex JVRS-100 vaccin adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001340 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001340</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is DHEA, which is relatively stable and can be directly incorporated into vaccine formulations.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>5-androsten-3β-ol-17-one</obo:IAO_0000118>
        <obo:IAO_0000118>DHA</obo:IAO_0000118>
        <obo:IAO_0000118>Dehydroepiandrosterone</obo:IAO_0000118>
        <obo:IAO_0000118>androstenolone</obo:IAO_0000118>
        <obo:IAO_0000118>prasterone</obo:IAO_0000118>
        <obo:IAO_0000118>transdehydroandrosterone</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>DHEA vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001341 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001341">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001341</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is PLGA, which has been used in the controlled delivery of peptide drugs.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>PLGA</obo:IAO_0000118>
        <obo:IAO_0000118>PLGA microspheres</obo:IAO_0000118>
        <obo:IAO_0000118>Polyester poly (DL-lactide-co-glycolide)</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15560948</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>DL-PGL (Polyester poly (DL-lactide-co-glycolide)) vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001342 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001342">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001353"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001342</metadata:prefixIRI>
        <obo:IAO_0000115>A cytokine vaccine adjuvant that uses the adjuvant effect of cytokine IL-15.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>IL-15 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001343 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001343">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000366"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001343</metadata:prefixIRI>
        <obo:IAO_0000115>A liposome-based vaccine adjuvant which is prepared from dehydration-rehydration vesicles (DRVs).</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>immunoliposomes containing antibodies to costimulatory molecules</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001344 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001344">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000388"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001344</metadata:prefixIRI>
        <obo:IAO_0000115>An E. coli LT toxin derived vaccine adjuvant that is a mutant form of heat-labile Escherichia coli enterotoxin (LT) that contains a substitution Ala -&gt; Arg  in position 72 of the A subunit.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:9529328</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>LTK72 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001345 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001345">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001345</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant containing MPL and squalene.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:12213399</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>MPL-SE vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001346 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001346">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000851"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16842"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000885"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001346</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16842"/>
        <obo:IAO_0000115>a vaccine preservative that contains formaldehyde.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.mja.com.au/public/issues/184_04_200206/eld10500_fm.pdf</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000885"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>formaldehyde vaccine preservative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001347 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001347">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001348"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001347</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derived vaccine adjuvant made of E112K mC,  a mutated CT created by substituting a single amino acid in the ADP-ribosyltransferase active centre, glutamate to lysine at position 112.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>mCT</obo:IAO_0000118>
        <obo:IAO_0000118>non-toxic mutant E112K of Cholera Toxin mCT-E112K</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:11251876</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>non-toxic mutant E112K of Cholera Toxin mCT-E112K vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001348 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001348">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001348</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant that is derived from cholera toxin.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>cholera toxin derived vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001349 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001349">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001354"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001349</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant that is composed of threonyl-MDP (0.05-1%) in an emulsion vehicle [5% squalane, 2.5% Pluronic(R) L121, 0.2% Polysorbate 80 and phosphate buffered saline (pH 7.4)].</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>SAF-1 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001350 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001350">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000366"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001350</metadata:prefixIRI>
        <obo:IAO_0000115>A liposome-based vaccine adjuvant that includes the glycoproteins of Sendai virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Sendai Proteoliposomes, Sendai-containing Lipid Matrices</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001351 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001351">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001357"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001351</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine adjuvant that is threonyl muramyl dipeptide (TMDP).</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>N-acetyl muramyl-L-threonyl-D-isoglutamine</obo:IAO_0000118>
        <obo:IAO_0000118>Termurtide™</obo:IAO_0000118>
        <obo:IAO_0000118>[thr1 ]-MDP</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>threonyl muramyl dipeptide (TMDP) vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001352 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001352">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000118"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001352</metadata:prefixIRI>
        <obo:IAO_0000115>A microbial derivative vaccine adjuvant made of virus like particles (VLPS) containing the yeast retrotransposon Ty which has the amino acids 1-381 of the pI protein encoded.</obo:IAO_0000115>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>Ty-VLPs</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:7551218</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>ty particles vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001353 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001353">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001353</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant that contains active cytokine compound.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>cytokine vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001354 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001354">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001354</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant that is composed of differnt compounds under more than one category.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>combination vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001355 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001355">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001355</metadata:prefixIRI>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>emulsion vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001356 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001356">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001356</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant that serves as a particulate antigen delivery system.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>particulate antigen delivery system vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001357 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001357">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001357</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant that contains synthetic material.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>synthetic vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001358 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001358">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001358</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant that includes tensioactive material. Tensioactive materials, surfactants or active surface agents are chemical substances with a polar-non polar structure. These substances have a tendency to locate themselves at the surface creating an adsorbed monomolecular layer on the interface.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <obo:IAO_0000118>tensioactive compound vaccine adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>WEB: http://www.citt.ufl.edu/team/sepulveda/html/en_tensioactivos.htm</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>tensoactive compound vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001359">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001359</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant that is primarily composed of carbohydrates.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>carbohydrate vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001360 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001360">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001353"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001360</metadata:prefixIRI>
        <obo:IAO_0000115>A cytokine vaccine adjuvant that includes IFN-gamma.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Samantha G. Sayers</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>IFN-gamma vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001361 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001361">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001361</metadata:prefixIRI>
        <obo:IAO_0000115>a role that is inherenced in a gene that can be mutated in a virulent pathogen, leading to an attenuated strain serving as a live attenuated vaccine strain.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>virmugen role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001362 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001362">
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005503"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001362</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine that targets for allergy.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1205"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>allergy vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001363 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001363">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001363</metadata:prefixIRI>
        <obo:IAO_0000115>bacterial vaccine that is used to protect against Clostridium perfringens infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1502"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Clostridium perfringens vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001364 -->

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        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>human immunization objective</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001365 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001365">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052518"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052518"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001365</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with CCHF virus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CCHF vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052518"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Crimean-Congo Haemorrhagic Fever vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001366 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001366">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39944"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003537"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39944"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001366</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Caprine herpesvirus type 1 virus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39944"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Caprine herpesvirus type 1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001367 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001367">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000017"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001367</metadata:prefixIRI>
        <obo:IAO_0000115>an inactivation vaccine that is prepared by heat inactivation.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>heat-killed vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001368 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001368">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000315"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001368</metadata:prefixIRI>
        <obo:IAO_0000115>an inactivation vaccine that is prepared by irradiation inactivation.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>irradiation-inactivated vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001369 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001369">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000017"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001369</metadata:prefixIRI>
        <obo:IAO_0000115>an inactivation vaccine that is prepared by H2O2 inactivation.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>H2O2-killed vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001370 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001370">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000017"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001370</metadata:prefixIRI>
        <obo:IAO_0000115>an inactivation vaccine that is prepared by formalin inactivation.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>formalin-killed vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001371 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001371">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000178"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001371</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine prepraration process that is performed by H2O2 inactivation of virulent pathogen.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>inactivated vaccine preparation using H2O2 inactivation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001372 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001372">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001372</metadata:prefixIRI>
        <obo:IAO_0000115>an organismal quality that indicates an organism (e.g., human) is not yet immunized against a disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>unimmunized</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001373 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001373">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000151"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001373</metadata:prefixIRI>
        <obo:IAO_0000115>an organismal quality that indicates an organism (e.g., human) is immunized against a disease through vaccination with a licensed vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>immunized by vaccination with a licensed vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001374 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001374">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001374</metadata:prefixIRI>
        <obo:IAO_0000115>an organism that is vaccinated with a vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccinated organism</obo:IAO_0000118>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>vaccinee</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001375 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001375">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001375</metadata:prefixIRI>
        <obo:IAO_0000115>A Streptococcus  vaccine against Streptococcus agalactiae infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus agalactiae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001376 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001376">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001376</metadata:prefixIRI>
        <obo:IAO_0000115>an organismal quality that indicates an organism (e.g., human) is vaccinated with a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccinated</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001377 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001377">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0001995"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001377</metadata:prefixIRI>
        <obo:IAO_0000115>an organismal quality that indicates an organism (e.g., human) is unvaccinated with any vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>unvaccinated</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001378 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001378">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001376"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001378</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccinated quality that indicates an organism is vaccinated with a licensed vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>vaccinated with a licensed vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001379 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001379">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001377"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001379</metadata:prefixIRI>
        <obo:IAO_0000115>a unvaccinated quality that indicates an organism has not been vaccinated with a licensed vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:label>unvaccinated with a licensed vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001380 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001380">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000344"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001380</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:8306370</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3066</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/295</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000344"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3066</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>B16 Vaccine adjuvanted by Loxoribine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001381 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001381">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001381</metadata:prefixIRI>
        <obo:IAO_0000115>an organism that is immunized for a disease</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>immunized organism</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001382 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001382">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11976"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11976"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001382</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Rabbit hemorrhagic disease virus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11976"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabbit hemorrhagic disease virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001383 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001383">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0100026"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001383</metadata:prefixIRI>
        <obo:IAO_0000115>an organism that is unvaccinated with a vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>unvaccinated organism</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001384 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001384">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001384</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene from Actinobacillus pleuropneumoniae.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Actinobacillus pleuropneumoniae gene</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001385 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001385</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Trypanosoma cruzi.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001386 -->

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        <obo:IAO_0000115>A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi CRP-10 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine encoding CRP-10</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine encoding CRP-10</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001387 -->

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        <obo:IAO_0000115>A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi G2 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine encoding G2</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine encoding G2</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001388 -->

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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001388</metadata:prefixIRI>
        <obo:IAO_0000115>A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi G4 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine encoding G4</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine encoding G4</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001389 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001389</metadata:prefixIRI>
        <obo:IAO_0000115>A T. cruzi DNA vaccine that uses a DNA plasmid expressing T. cruzi TSA-1 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine encoding TSA-1</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011296"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine encoding TSA-1</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001390 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001390</metadata:prefixIRI>
        <obo:IAO_0000115>A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi TSA-1 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine pGFP-TSA1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=811</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>811</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine pGFP-TSA1</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001391 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001391</metadata:prefixIRI>
        <obo:IAO_0000115>A T. cruzi subunit vaccine that uses T. cruzi PAR1 protein as protective antigen.</obo:IAO_0000115>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>806</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi PAR1 protein vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001392 -->

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        <obo:IAO_0000115>A T. cruzi subunit vaccine that uses T. cruzi PAR2 protein as protective antigen.</obo:IAO_0000115>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>810</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi PAR2 protein vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001393 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001393</metadata:prefixIRI>
        <obo:IAO_0000115>A T. cruzi vaccine that uses attenuated Salmonella to express T. cruzi Cruzipain protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi vaccine using attenuated Salmonella expressing T. cruzi Cruzipain</obo:IAO_0000118>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>804</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi vaccine using attenuated Salmonella expressing Trypanosoma cruzi Cruzipain</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001394 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001394</metadata:prefixIRI>
        <obo:IAO_0000115>A T. cruzi vaccine that uses Sendai virus vector to express T. cruzi amastigote surface protein-2.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi vaccine using Sendai virus vector expressing amastigote surface protein-2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=802</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>802</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi vaccine using Sendai virus vector expressing amastigote surface protein-2</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001395 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001395">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001395</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine that contains two or more individual vaccines. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>cocktail vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001396 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001396">
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001396</metadata:prefixIRI>
        <obo:IAO_0000115>a cocktail vaccine that contains both subunit vaccine and inactivated whole organism vaccines.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000504"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>cocktail vaccine containing subunit vaccine and inactivated whole organism vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001397 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001397">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000401"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001397</metadata:prefixIRI>
        <obo:IAO_0000115>a prime-boost vaccine with DNA vaccine priming that contains a subunit vaccine for boosting</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vaccine containing DNA vaccine for priming and subunit vaccine for boosting</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001398 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001398">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000401"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001398</metadata:prefixIRI>
        <obo:IAO_0000115>a prime-boost vaccine with a DNA vaccine priming that contains a Ad vector vaccine for boosting</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vaccine containing DNA vaccine for priming and Ad vector vaccine for boosting</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001399 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001399">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001399</metadata:prefixIRI>
        <obo:IAO_0000115>a conjugate vaccine that conjugate more than one open reading frames of protective antigens or conjugate a protective antigen to a carrier protein.</obo:IAO_0000115>
        <obo:IAO_0000116>An example of fusion protein vaccine is Mtb72f fusion protein vaccine. Reference: PubMed: 15187142.</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>fusion protein vaccine</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>fusion conjugate protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001400 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001400">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000790"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001400</metadata:prefixIRI>
        <obo:IAO_0000115>A Brucella gene that is from B. melitensis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001401 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001401">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000790"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001401</metadata:prefixIRI>
        <obo:IAO_0000115>A Brucella gene that is from B. suis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29461"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Brucella suis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001402 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001402">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001402</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Bacillus anthracis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001403 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001403">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1639"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001403</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Listeria monocytogenes.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1639"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Listeria monocytogenes gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001404 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001404">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1764"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001404</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Mycobacterium avium.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1764"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium avium gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001405 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001405">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001405</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Staphylococcus aureus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001406 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001406">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_644"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001406</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Aeromonas hydrophila.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_644"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Aeromonas hydrophila gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001407 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001407">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001407</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Bordetella bronchiseptica.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Bordetella bronchiseptica gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001408 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001408">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001408</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Aeromonas salmonicida.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Aeromonas salmonicida gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001409 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001409">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001409</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Bordetella pertussis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001410 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001410">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001410</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Borrelia burgdorferi.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Borrelia burgdorferi gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001411 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001411">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001411</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Burkholderia pseudomallei.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Burkholderia pseudomallei gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001412 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001412">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001412</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Edwardsiella ictaluri.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Edwardsiella ictaluri gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001413 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001413">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001413</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Edwardsiella tarda.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Edwardsiella tarda gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001414 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001414">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001414</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Francisella tularensis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001415 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001415">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001415</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Mannheimia haemolytica.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Mannheimia haemolytica gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001416 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001416">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001416</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Mycoplasma gallisepticum.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma gallisepticum gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001417 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001417">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001417</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Neisseria meningitidis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001418 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001418">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001418</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Pasteurella multocida.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Pasteurella multocida gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001419 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001419">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000168"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001419</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Salmonella Typhi.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Salmonella Typhi gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001420 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001420">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000168"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_594"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001420</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Salmonella Gallinarum.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_594"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Salmonella Gallinarum gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001421 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001421">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000168"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001421</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Salmonella Typhimurium.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Salmonella Typhimurium gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001422 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001422">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000168"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149539"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001422</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Salmonella Enteritidis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149539"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Salmonella Enteritidis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001423 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001423">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001423</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Vibrio cholerae.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Vibrio cholerae gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001424 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001424">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001424</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Bovine herpesvirus 1.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001425 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001425">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001425</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Yersinia enterocolitica.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Yersinia enterocolitica gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001426 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001426">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001426</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Yersinia pestis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001427 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001427">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_633"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001427</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Yersinia pseudotuberculosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_633"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Yersinia pseudotuberculosis gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001428 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001428">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29486"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001428</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Yersinia ruckeri.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29486"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Yersinia ruckeri gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001429 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001429">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001429</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Bovine Respiratory Syncytial Virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Bovine Respiratory Syncytial Virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001430 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001430">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001430</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Classical swine fever virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Classical swine fever virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001431 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001431">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001431</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Equid herpesvirus 1.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Equid herpesvirus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001432 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001432">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10334"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001432</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Feline herpesvirus 1.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10334"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Feline herpesvirus 1 gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001433 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001433">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11673"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001433</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Feline immunodeficiency virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11673"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Feline immunodeficiency virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001434 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001434">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11135"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001434</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Feline infectious peritonitis virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11135"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Feline infectious peritonitis virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001435 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001435">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001435</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Gallid herpesvirus 1.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Gallid herpesvirus 1 gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001436 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001436">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001436</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Hepatitis B virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001437 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001437">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001437</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Human herpesvirus 1.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Human herpesvirus 1 gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001438 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001438">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162145"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001438</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Human metapneumovirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162145"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Human metapneumovirus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001439 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001439">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001439</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Human Respiratory Syncytial Virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Human Respiratory Syncytial Virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001440 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001440">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001440</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Infectious Hematopoietic Necrosis Virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Infectious Hematopoietic Necrosis Virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001441 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001441">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001441</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Porcine respiratory and reproductive syndrome virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Porcine respiratory and reproductive syndrome virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001442 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001442">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001442</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Pseudorabies virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>Suid herpesvirus 1 gene</obo:IAO_0000118>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001443 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001443">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001443</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Rabies virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Rabies virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001444 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001444">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_694009"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001444</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from SARS-CoV.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_694009"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>SARS-CoV gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001445 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001445">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001445</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Simian Immunodeficiency Virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Simian Immunodeficiency Virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001446 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001446">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001446</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Tick-borne Encephalitis Virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Tick-borne Encephalitis Virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001447 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001447">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001447</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from VEE Virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>VEE Virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001448 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001448">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001448</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from West Nile virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <oboInOwl:hasAlternativeId>VO:0000197</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>West Nile virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001449 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001449">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001449</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Western equine encephalomyelitis virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Western equine encephalomyelitis virus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001450 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001450">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000174"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001450</metadata:prefixIRI>
        <obo:IAO_0000115>A protozoan gene that is from Leishmania donovani.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001451 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001451">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000171"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5821"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001451</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium gene that is from Plasmodium berghei.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5821"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Plasmodium berghei gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001452 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001452">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000171"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001452</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium gene that is from Plasmodium yoelii.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001453 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001453">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000170"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001453</metadata:prefixIRI>
        <obo:IAO_0000115>A protozoan gene that is from Toxoplasma gondii.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001454 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001454">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000156"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001454</metadata:prefixIRI>
        <obo:IAO_0000115>A viral gene that is from Human herpesvirus 2.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Human herpesvirus 2 gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001455 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001455">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11241"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003543"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11241"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001455</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Rinderpest virus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11241"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rinderpest virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001456">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003554"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001456</metadata:prefixIRI>
        <obo:IAO_0000115>bacterial vaccine that is used to protect against Erysipelothrix rhusiopathiae infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Erysipelothrix rhusiopathiae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001457 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001457">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_56690"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_56690"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001457</metadata:prefixIRI>
        <obo:IAO_0000115>protozoan vaccine that is used to protect against Tritrichomonas suis infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_56690"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trichomonas foetus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001459 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001459">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001459</metadata:prefixIRI>
        <obo:IAO_0000115>protozoan vaccine that is used to protect against Eimeria spp. (Eimeria) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/762"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000906"/>
        <rdfs:label>obsolete Eimeria spp. vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001460 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001460">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10258"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000512"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001460</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Orf Virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10258"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Orf Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001461 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001461">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001218"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001461</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing birds.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>Aves vaccine</obo:IAO_0000118>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bird vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001462 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001462">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117565"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7898"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001218"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117565"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7898"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001462</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing fishes.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117565"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7898"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>fish vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001463 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001463">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001463</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Fowlpox virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000985"/>
        <rdfs:label>obsolete Fowlpox virus vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001464 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001464">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33554"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001218"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33554"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001464</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing carnivora.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_33554"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>carnivora vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001465 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001465">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001464"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001465</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing cat (felis catus).</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>cat vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001466 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001466">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001218"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001466</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing cattle.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>cattle vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001467 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001467">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001467</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing dog (Canis familiaris).</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>dog vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001468 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001468">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001461"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001468</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing chicken.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>chicken vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001469 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001469">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001461"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001469</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing duck.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>duck vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001470 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001470">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7995"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001462"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001470</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing catfish.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>catfish vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001471 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001471">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001464"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001471</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing gray wolf.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>gray wolf vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001472 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001472">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9788"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001218"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9788"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001472</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing horse.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>horse vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001473 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001473">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9224"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001461"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9224"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001473</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing parrot.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9224"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>parrot vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001474 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001474">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001218"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001474</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing pig.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pig vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001475 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001475">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9768"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001218"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9768"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001475</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing sei whale.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9768"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>sei whale vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001476 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001476">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001218"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001476</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing sheep.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>sheep vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001477 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001477">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_504568"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001462"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_504568"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001477</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing  salmoninae (tourts, salmons &amp; chars).</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_504568"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>salmoninae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001478 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001478">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9103"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001461"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9103"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001478</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that used for immunizing turkey.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9103"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>turkey vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001479 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001479">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001479</metadata:prefixIRI>
        <obo:IAO_0000115>The objective that intends to produce vaccine via the vaccine preparation process.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccine target specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001480 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001480">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40050"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003542"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40050"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001480</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with African horse sickness virus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40050"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>African horse sickness virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001481 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001481">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10264"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000512"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10264"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001481</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Pigeonpox virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10264"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pigeonpox virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001482 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001482">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001482</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Bovine herpesvirus 1 infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>BHV-1 vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>Bovine rhinotracheitis vaccine</obo:IAO_0000118>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/688"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:label>obsolete bovine herpesvirus 1 vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001483 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001483">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12455"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12455"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001483</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Borna disease virus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12455"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borna disease virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001484 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001484">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001484</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Caprine herpesvirus 1</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001366"/>
        <rdfs:label>obsolete Caprine herpesvirus 1 vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001485 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001485</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine licensed in the USA</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm093833.htm</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000812"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>USA licensed vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001486 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001486">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003537"/>
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            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001486</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Equid herpesvirus 1 infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equid herpesvirus 1 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001487 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001487">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001487</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Feline herpesvirus 1 (Felid herpesvirus 1) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10334"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline herpesvirus 1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001488 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001488</metadata:prefixIRI>
        <obo:IAO_0000115>Viral vaccine that is used to protect against Gallid herpesvirus 1 infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Gallid_herpesvirus_1</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Gallid herpesvirus 1 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001489 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001489">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001489</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Canine adenovirus type 1 (Canine adenovirus 1) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10512"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>canine adenovirus type 1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001490 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001490</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Canine Adenovirus Type 2 (Canine adenovirus 2) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10514"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>canine adenovirus Type 2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001491 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001491</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Bovine papillomavirus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10571"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine papillomavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001492 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001492</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Avian Polyomavirus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian polyomavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001493 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001493</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Mink enteritis virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10792"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink enteritis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001494 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001494</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Porcine parvovirus infection</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine parvovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001495 -->

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        <obo:IAO_0000115>viral vaccine that is used to protect against Porcine rotavirus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10913"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine rotavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001496 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001496</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Equine rotavirus infection</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equine rotavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001497 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001497</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Infectious Bursal Disease Virus (IBDV) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>IBDV vaccine</obo:IAO_0000118>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>infectious bursal disease virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001498 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001498">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001498</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Eastern Equine Encephalitis Virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11021"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eastern Equine Encephalitis Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001499 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001499">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
                    </owl:Restriction>
                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001499</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against VEE Virus (Venezuelan equine encephalitis virus) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VEE Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001500 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001500">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11047"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001500</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Equine arteritis virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11047"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equine arteritis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001501 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001501">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003546"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001501</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Bovine viral diarrhea virus 1 infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine viral diarrhea virus 1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001502 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001502">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004897"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001502</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Infectious Bronchitis Virus (IBV) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Infectious Bronchitis Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001503 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001503">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11128"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001503</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Bovine coronavirus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11128"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bovine coronavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001504 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001504">
        <owl:equivalentClass>
            <owl:Class>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001504</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Feline infectious peritonitis virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11135"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline infectious peritonitis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001505 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001505">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001505</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Transmissible gastroenteritis virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11149"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Transmissible gastroenteritis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001506 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001506">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001506</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00023647</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12833467</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/697"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000990"/>
        <rdfs:label>obsolete Bovine Parainfluenza 3 Virus vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001507 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001507">
        <owl:equivalentClass>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001507</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Bovine Respiratory Syncytial Virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Respiratory Syncytial Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001508 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001508">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11673"/>
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            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001508</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Feline immunodeficiency virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11673"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline immunodeficiency virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001509 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001509">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11978"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001509</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Feline calicivirus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11978"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline calicivirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001510 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001510">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12618"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001510</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Chicken Anemia Virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12618"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>chicken anemia virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001511 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001511">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001511</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Porcine respiratory and reproductive syndrome virus (Porcine reproductive and respiratory syndrome virus) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine respiratory and reproductive syndrome virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001512 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001512">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001512</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Riemerella anatipestifer infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_34085"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Riemerella anatipestifer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001513 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001513">
        <owl:equivalentClass>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38170"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001468"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003541"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001513</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Avian Reovirus (Avian orthoreovirus) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38170"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian reovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001514 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001514">
        <owl:equivalentClass>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38525"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001461"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38525"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001514</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against avian pneumovirus (avian metapneumovirus) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38525"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian pneumovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001515 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001515">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
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                </owl:intersectionOf>
            </owl:Class>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003542"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001515</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Bluetongue virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bluetongue virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001516 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001516">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_41678"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000037"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_41678"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001516</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Turkey hemorrhagic enteritis virus (Turkey adenoirus 3) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_41678"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Turkey hemorrhagic enteritis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001517 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001517">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_44088"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000512"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_44088"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001517</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Canarypox virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_44088"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canarypox virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001518 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001518">
        <owl:equivalentClass>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_50294"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000727"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001518</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Psittacid herpesvirus 1 infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_50294"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Psittacid herpesvirus 1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001519 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001519">
        <owl:equivalentClass>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001519</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against infection with Mycobacterium bovis</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium bovis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001520 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001520">
        <owl:equivalentClass>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_55987"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001520</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Infectious salmon anemia virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_55987"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Infectious salmon anemia virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001521 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001521">
        <owl:equivalentClass>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_67780"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001521</metadata:prefixIRI>
        <obo:IAO_0000115>An Edwardsiella bacterial vaccine that is used to protect against Edwardsiella ictaluri infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_67780"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Edwardsiella ictaluri vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001522 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001522">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001461"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001522</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Avian Encephalomyelitis Virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian encephalomyelitis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001523 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001523">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001523</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Mannheimia haemolytica infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mannheimia haemolytica vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001524 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001524">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
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            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001474"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001524</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Porcine circovirus 2 infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>porcine circovirus 2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001525 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001525">
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_104388"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000727"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001469"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001525</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Duck enteritis virus (Anatid herpesvirus 1) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_104388"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Duck enteritis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001526 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001526">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001526</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Canine parainfluenza virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>canine parainfluenza virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001527 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001527">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001461"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_260963"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001527</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Avian Paramyxovirus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_260963"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian paramyxovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001528 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001528">
        <owl:equivalentClass>
            <owl:Class>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_691956"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_691956"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001528</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Duck hepatitis virus 1 (Duck hepatitis A virus) infection</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_691956"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Duck hepatitis virus 1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001530 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001530">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001517"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8825"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001530</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1557</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8825"/>
        <obo:VO_0001818>1557</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1623.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canary Pox Modified Live Virus Vaccine (USDA: 1623.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001531 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001531</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2092</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8825"/>
        <obo:VO_0001818>2092</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10264"/>
        <oboInOwl:hasDbXref>USDA: 1881.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pigeon Pox Live Virus Vaccine (USDA: 1881.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001532 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001532">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001481"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001532</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2093</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2093</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10264"/>
        <oboInOwl:hasDbXref>USDA: 1881.12</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pigeon Pox Live Virus Vaccine (USDA: 1881.12)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001533 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10264"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001533</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2094</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2094</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1881.14</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pigeon Pox Live Virus Vaccine (USDA: 1881.14)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001534 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001534">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000513"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8825"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001534</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2111</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8825"/>
        <obo:VO_0001818>2111</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 18E1.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Quail Pox Live Virus Vaccine (USDA: 18E1.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001535 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001535">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001464"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9625"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10512"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000056"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001535</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1925</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9625"/>
        <obo:VO_0001818>1925</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10512"/>
        <oboInOwl:hasDbXref>USDA: 1635.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fox Encephalitis Killed Virus Vaccine (USDA: 1635.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001536 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001536">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010475"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000056"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001536</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1967</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
        <obo:VO_0001818>1967</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:hasDbXref>USDA: 1451.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Distemper Modified Live Virus Vaccine (USDA: 1451.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001537 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001537">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010475"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001537</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1968</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
        <obo:VO_0001818>1968</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:hasDbXref>USDA: 1451.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Distemper Modified Live Virus Vaccine (USDA: 1451.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001538 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001538">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010475"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001538</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1969</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
        <obo:VO_0001818>1969</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:hasDbXref>USDA: 1451.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Distemper Modified Live Virus Vaccine (USDA: 1451.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001539 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001539">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000652"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010475"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10792"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001539</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1972</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
        <obo:VO_0001818>1972</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10792"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Enteritis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001540 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001540">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000652"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001509"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11978"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001540</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001541 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001542 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001543 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Feline immunodeficiency virus Killed Virus Vaccine (USDA: 15A5.23)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001544 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Feline Infectious Peritonitis Modified Live Virus Vaccine (USDA: 15A1.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001545 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Feline Leukemia Killed Virus Vaccine (USDA: 1555.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001546 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001547 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001548 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001549 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001550 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001551 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001552 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001553 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001554 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001555 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Feline Rhinotracheitis Modified Live Virus Vaccine (USDA: 16A1.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001556 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Edwardsiella ictaluri Avirulent Live Culture Vaccine (USDA: 1531.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001557 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1011.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Anthrax Spore live culture Vaccine (USDA: 1011.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001558 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1095.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001559 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Bovine Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1095.21)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001560 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1178</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1091.20</oboInOwl:hasDbXref>
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        <rdfs:label>Bovine Respiratory Syncytial Virus Vaccine Modified Live Virus (USDA: 1091.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001561 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Bovine Rhinotracheitis Killed Virus Vaccine (USDA: 1105.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001562 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1181</obo:IAO_0000119>
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        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001563 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001564 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1183</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1101.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.21)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001565 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1101.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001566 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1185</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.B0)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001567 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000057"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001567</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1354</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1354</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1205.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001568 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001568">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001501"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001568</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1355</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1355</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1205.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001569 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001569">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001501"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001569</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1356</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1356</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1205.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001570 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001570">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001570</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1357</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1357</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1205.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001571 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001571</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1358</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1358</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1205.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001572 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001572">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001501"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001572</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1351</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1351</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1201.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Modified Live Virus Vaccine (USDA: 1201.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001573 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001573">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001501"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001573</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1352</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1352</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1201.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Modified Live Virus Vaccine (USDA: 1201.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001574 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001574</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1353</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1353</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1201.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Modified Live Virus Vaccine (USDA: 1201.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001575 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001575</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1383</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1383</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1251.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella Abortus Strain 19, Live Culture Vaccine (USDA: 1251.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001576 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001576</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1384</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1384</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1251.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella Abortus Strain 19, Live Culture, Reduced Dose Vaccine (USDA: 1251.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001577 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001577">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000021"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001577</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1385</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1385</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1261.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella Abortus Strain RB-51, Live Culture Vaccine (USDA: 1261.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001578 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001578</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2077</obo:IAO_0000119>
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        <obo:VO_0001818>2077</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1841.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1841.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001579 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001579">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001579</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2078</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1841.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1841.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001580 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001580</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2121</obo:IAO_0000119>
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        <obo:VO_0001818>2121</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:hasDbXref>USDA: 19A1.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella Choleraesuis Avirulent Live Culture Vaccine (USDA: 19A1.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001581 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001581">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001581</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2122</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2122</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:hasDbXref>USDA: 19A1.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella Choleraesuis Avirulent Live Culture Vaccine (USDA: 19A1.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001582 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001582">
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001582</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2123</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2123</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:hasDbXref>USDA: 19D1.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella Dublin Live Culture Vaccine (USDA: 19D1.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001583 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001583">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000315"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_56690"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001583</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2143</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2143</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_56690"/>
        <oboInOwl:hasDbXref>USDA: 1859.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trichomonas Foetus Killed Protozoa Vaccine (USDA: 1859.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001584 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001584">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001584</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118>Wart Vaccine (Colorado Serum)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2144</obo:IAO_0000119>
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        <obo:VO_0001818>2144</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1985.50</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Wart Killed Virus Vaccine (USDA: 1985.50)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001585 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001585</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1124</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1124</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1015.I0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Encephalomyelitis Killed Virus Vaccine (USDA: 1015.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001586 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001586</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1125</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 1051.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001587 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001588 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001589 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001590 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001591 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001592 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001593 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001594 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001595 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001596 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001597 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001601 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>avian influenza H5N3 Subtype, Killed Virus Vaccine (USDA: 1057.R3)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001602 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>avian influenza H9N2 Subtype, Killed Virus Vaccine (USDA: 1057.H9)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001603 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Avian Paramyxovirus Type 1, Killed Virus Vaccine (USDA: 10C5.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001604 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 10C5.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001605 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Avian Pneumovirus Modified Live Virus Vaccine (USDA: 1A31.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001606 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001607 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001607</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1167</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1167</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1045.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Reovirus Killed Virus Vaccine (USDA: 1045.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001608 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001608</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1168</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1168</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1045.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Reovirus Killed Virus Vaccine (USDA: 1045.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001609 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001609</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1169</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1045.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Reovirus Killed Virus Vaccine (USDA: 1045.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001610 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001610</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1361</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1231.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001611 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001611</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1373</obo:IAO_0000119>
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        <obo:VO_0001818>1373</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.1M</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.1M)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001612 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001612</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1375</obo:IAO_0000119>
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        <obo:VO_0001818>1375</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001613 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001613</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1376</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1231.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001614 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001614</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1377</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1377</obo:VO_0001818>
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        <rdfs:label>Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.22)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001615 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001615</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1365</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1365</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.15</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Conn Type, Live Virus Vaccine (USDA: 1231.15)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001616 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1368</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1231.1D</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Delaware Type, Modified Live Virus Vaccine (USDA: 1231.1D)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001617 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001617</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1371</obo:IAO_0000119>
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        <obo:VO_0001818>1371</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.1J</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Georgia Type, Live Virus Vaccine (USDA: 1231.1J)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001618 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001618</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1372</obo:IAO_0000119>
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        <obo:VO_0001818>1372</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.1L</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Georgia Type, Live Virus Vaccine (USDA: 1231.1L)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001619 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001619</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1382</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1235.15</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass &amp; Ark Types, Killed Virus Vaccine (USDA: 1235.15)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001620 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001620</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1363</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1363</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.13</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass &amp; Ark Types, Live Virus Vaccine (USDA: 1231.13)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001621 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001621">
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001621</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1364</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1364</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.14</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1231.14)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001622 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001622">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001622</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1370</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1370</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.1G</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1231.1G)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001623 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001623">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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            <owl:Restriction>
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        <rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001623</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1374</obo:IAO_0000119>
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        <obo:VO_0001818>1374</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA:1231.1N</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass &amp; Conn Types, Live Virus Vaccine (USDA:1231.1N)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001624 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001624">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001624</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1362</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1362</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.12</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.12)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001625 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001625</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1366</obo:IAO_0000119>
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        <obo:VO_0001818>1366</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.18</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.18)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001626 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001626</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1367</obo:IAO_0000119>
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        <obo:VO_0001818>1367</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1231.1A</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.1A)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001627 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001627</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1369</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1369</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:hasDbXref>USDA: 1231.1F</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.1F)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001628 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001628">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001502"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001628</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1378</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1378</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1232.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass Type, Live Virus Vaccine (USDA: 1232.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001629 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001629">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001502"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001629</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1379</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1379</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1232.15</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass Type, Live Virus Vaccine (USDA: 1232.15)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001630 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001630">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001630</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1380</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1380</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:hasDbXref>USDA: 1233.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass Type, Live Virus Vaccine (USDA: 1233.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001631 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001631">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001502"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001631</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1381</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1381</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1235.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bronchitis Mass Type, Live Virus Vaccine (USDA: 1235.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001632 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001632">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000960"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001632</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1403</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1403</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1275.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease Killed Virus Vaccine (USDA: 1275.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001633 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001633">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001633</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1404</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1404</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1275.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease Killed Virus Vaccine (USDA: 1275.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001634 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001634">
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1405</obo:VO_0001818>
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        <rdfs:label>Bursal Disease Killed Virus Vaccine (USDA: 1275.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001635 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1386</obo:IAO_0000119>
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        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001636 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001637 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001638 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1389</obo:IAO_0000119>
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        <obo:VO_0001818>1389</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1271.04</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.04)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001639 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001639</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1390</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1271.0A</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.0A)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001640 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001640</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001641 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1392</obo:IAO_0000119>
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        <obo:VO_0001818>1392</obo:VO_0001818>
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        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.11)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001642 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.12)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001643 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.13)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001644 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1271.16</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.16)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001645 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1397</obo:IAO_0000119>
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        <obo:VO_0001818>1397</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.17)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001646 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Bursal Disease Live Virus Vaccine (USDA: 1271.18)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001647 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001648 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001649 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001650 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001651 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001652 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001655 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001656 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001657 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001658 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001659 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001660 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001661 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001662 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001663 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001664 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001665 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001666 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001667 -->

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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1707</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
        <oboInOwl:hasDbXref>USDA: 1431.58</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coccidiosis Live Oocysts Vaccine (USDA: 1431.58)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001668 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001668">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000906"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001668</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1708</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1708</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
        <oboInOwl:hasDbXref>USDA: 1431.59</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coccidiosis Live Oocysts Vaccine (USDA: 1431.59)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001669 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001669">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000906"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001669</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1709</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1709</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
        <oboInOwl:hasDbXref>USDA: 1431.5C</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coccidiosis Live Oocysts Vaccine (USDA: 1431.5C)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001670 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001670">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000906"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001670</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1704</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1704</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
        <oboInOwl:hasDbXref>USDA: 1431.55</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coccidiosis Live Oocysts, Chicken Isolates Vaccine (USDA: 1431.55)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001671 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001671">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001671</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1903</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1903</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:hasDbXref>USDA: 1601.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001672 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001672">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001672</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1904</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1904</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:hasDbXref>USDA: 1601.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001673 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001673">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001673</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1905</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1905</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:hasDbXref>USDA: 1601.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001674 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001674">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001674</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1906</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1906</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1601.13</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.13)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001675 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001675">
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            <owl:Restriction>
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            <owl:Restriction>
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            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001675</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1907</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1907</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:hasDbXref>USDA: 1601.14</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.14)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001676 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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            <owl:Restriction>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001676</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1908</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1908</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1601.15</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.15)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001677 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001677">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001677</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1913</obo:IAO_0000119>
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        <obo:VO_0001818>1913</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1621.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Pox Live Virus Vaccine (USDA: 1621.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001678 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001678">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001678</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1914</obo:IAO_0000119>
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        <obo:VO_0001818>1914</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1621.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Pox Live Virus Vaccine (USDA: 1621.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001679 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001679</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1915</obo:IAO_0000119>
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        <obo:VO_0001818>1915</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1621.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Pox Live Virus Vaccine (USDA: 1621.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001680 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001680</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1916</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1621.13</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Pox Live Virus Vaccine (USDA: 1621.13)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001681 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1917</obo:IAO_0000119>
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        <obo:VO_0001818>1917</obo:VO_0001818>
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        <rdfs:label>Fowl Pox Live Virus Vaccine (USDA: 1621.14)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001682 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1918</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1622.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Pox Live Virus Vaccine (USDA: 1622.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001683 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001683</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1945</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1945</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 16L1.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotype 1, Live Virus Vaccine (USDA: 16L1.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001684 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1948</obo:IAO_0000119>
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        <obo:VO_0001818>1948</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 16L1.04</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotype 1, Live Virus Vaccine (USDA: 16L1.04)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001685 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001685</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1952</obo:IAO_0000119>
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        <obo:VO_0001818>1952</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 16L1.09</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotype 1, Live Virus Vaccine (USDA: 16L1.09)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001686 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001686</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1934</obo:IAO_0000119>
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        <obo:VO_0001818>1934</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1631.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotype 2, Live Virus Vaccine (USDA: 1631.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001687 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001687</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1936</obo:IAO_0000119>
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        <obo:VO_0001818>1936</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1641.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotype 3, Live Virus Vaccine (USDA: 1641.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001688 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001689 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001690 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001691 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1946</obo:IAO_0000119>
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        <obo:VO_0001818>1946</obo:VO_0001818>
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        <rdfs:label>Marek&apos;s Disease Serotypes 1 &amp; 2 &amp; 3, Live Virus Vaccine (USDA: 16L1.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001692 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1631.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotypes 1 &amp; 3, Live Herpesvirus Chimera Vaccine (USDA: 1631.R0)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001693 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001694 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 16L1.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotypes 1 &amp; 3, Live Virus Vaccine (USDA: 16L1.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001695 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1951</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1951</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 16L1.08</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotypes 1 &amp; 3, Live Virus Vaccine (USDA: 16L1.08)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001696 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001696</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1939</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1939</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1651.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 1651.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001697 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001697</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1940</obo:IAO_0000119>
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        <obo:VO_0001818>1940</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1651.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 1651.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001698 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001698</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1941</obo:IAO_0000119>
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        <obo:VO_0001818>1941</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1651.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 1651.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001699 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001699</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1942</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1942</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1651.05</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 1651.05)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001700 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001700</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1943</obo:IAO_0000119>
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        <obo:VO_0001818>1943</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 16G1.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 16G1.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001701 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001701</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1950</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1950</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
        <oboInOwl:hasDbXref>USDA: 16L1.07</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 16L1.07)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001702 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001702">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000949"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001077"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001702</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1973</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1973</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <oboInOwl:hasDbXref>USDA: 1751.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma Gallisepticum Live Culture Vaccine (USDA: 1751.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001703 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001703">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000949"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001077"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001703</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1974</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1974</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <oboInOwl:hasDbXref>USDA: 1751.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma Gallisepticum Live Culture Vaccine (USDA: 1751.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001704 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001704">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001704</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1981</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1981</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1711.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001705 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001705">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001705</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1982</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1982</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1711.12</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.12)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001706 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001706">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001706</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1983</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1983</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1711.14</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.14)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001707 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001707">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001707</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1984</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1984</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1711.18</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.18)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001708 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001708">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001708</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1991</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1991</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 17A2.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 17A2.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001709 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001709">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001709</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1993</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1993</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 17B1.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, C2 Strain, Live VirusVaccine (USDA: 17B1.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001710 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001710">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001710</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1985</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1985</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1721.0A</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.0A)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001711 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001711">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001711</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1986</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1986</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1721.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001712 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001712">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001712</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1987</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1987</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1721.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001713 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001713">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001713</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1988</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1988</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1721.15</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.15)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001714 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001714">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001714</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1989</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1989</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1721.16</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.16)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001715 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001715">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001715</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1990</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1990</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1721.17</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.17)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001716 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001716">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
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            <owl:Restriction>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001716</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1977</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1977</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1705.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease Killed Virus Vaccine (USDA: 1705.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001717 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001717">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001717</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1978</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1978</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1705.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease Killed Virus Vaccine (USDA: 1705.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001718 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001718">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001718</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1979</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1979</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1705.13</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease Killed Virus Vaccine (USDA: 1705.13)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001719 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001719">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001719</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1980</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1980</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1705.15</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease Killed Virus Vaccine (USDA: 1705.15)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001720 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001720">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001720</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1976</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1976</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:hasDbXref>USDA: 1701.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease VG/GA Strain, Live Virus Vaccine (USDA: 1701.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001721 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001721">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001721</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1992</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1992</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 17A2.V1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease VG/GA Strain, Live Virus Vaccine (USDA: 17A2.V1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001722 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001722</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2087</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2087</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1871.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001723 -->

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            <owl:Restriction>
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            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001723</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2088</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 1871.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001724 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001724</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2089</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1871.03</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.03)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001725 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001725</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2090</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1871.04</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.04)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001726 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001726</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2091</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1871.05</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.05)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001727 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001727</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 19C1.00</oboInOwl:hasDbXref>
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        <rdfs:label>Salmonella Typhimurium Live Culture Vaccine (USDA: 19C1.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001728 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001728</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2125</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2125</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <oboInOwl:hasDbXref>USDA: 19C1.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella Typhimurium Live Culture Vaccine (USDA: 19C1.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001729 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001729">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001729</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2126</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2126</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <oboInOwl:hasDbXref>USDA: 19C1.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella Typhimurium Live Culture Vaccine (USDA: 19C1.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001730 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001730">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001019"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001730</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2139</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2139</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1951.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tenosynovitis Live Virus Vaccine (USDA: 1951.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001731 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001731">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001731</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2135</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2135</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1951.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001732 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001732">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001732</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2136</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2136</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1951.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001733 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001733">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001019"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001733</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2137</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2137</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1951.03</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.03)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001734 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001734">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001019"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001734</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2138</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2138</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1951.04</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.04)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001735 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001735">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001735</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2140</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2140</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1951.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001736 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001736">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001019"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001736</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2141</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2141</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1952.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tenosynovitis Modified Live Virus Vaccine (USDA: 1952.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001737 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001737">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001525"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007749"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_104388"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001458"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001737</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1712</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
        <obo:VO_0001818>1712</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_104388"/>
        <oboInOwl:hasDbXref>USDA: 1461.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Duck Virus Enteritis Modified Live Virus Vaccine (USDA: 1461.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001738 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001738">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007749"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_691956"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001738</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1713</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
        <obo:VO_0001818>1713</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_691956"/>
        <oboInOwl:hasDbXref>USDA: 14B1.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Duck Virus Hepatitis Modified Live Virus Vaccine (USDA: 14B1.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001739 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001739">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001512"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007749"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_34085"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001458"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001739</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2120</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
        <obo:VO_0001818>2120</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_34085"/>
        <oboInOwl:hasDbXref>USDA: 1811.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Riemerella Anatipestifer Avirulent Live Culture Vaccine (USDA: 1811.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001740 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001740">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000637"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000645"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117565"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_996"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001740</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1902</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117565"/>
        <obo:VO_0001818>1902</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_996"/>
        <oboInOwl:hasDbXref>USDA: 17F1.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flavobacterium Columnare Avirulent Live Culture Vaccine (USDA: 17F1.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001741 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001741">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000394"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001741</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1172</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1172</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
        <oboInOwl:hasDbXref>USDA: 1081.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella Bronchiseptica Avirulent Live Culture Vaccine (USDA: 1081.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001742 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001742">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000394"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001742</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1173</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1173</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1081.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella Bronchiseptica Avirulent Live Culture Vaccine (USDA: 1081.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001743 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001743</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1562</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1562</obo:VO_0001818>
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        <rdfs:label>Canine Coronavirus Killed Virus Vaccine (USDA: 14P5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001744 -->

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            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001744</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1563</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1563</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 14P5.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Killed Virus Vaccine (USDA: 14P5.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001745 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001745">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001745</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1561</obo:IAO_0000119>
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        <obo:VO_0001818>1561</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 14P1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Modified Live Virus Vaccine (USDA: 14P1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001746 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001746</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1691</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 15K5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>canine influenza H3N8, killed virus vaccine (USDA: 15K5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001747 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001747</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1692</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1421.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Parainfluenza Modified Live Virus Vaccine (USDA: 1421.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001748 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001748</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1711</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1471.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Distemper Live Canarypox Vector Vaccine (USDA: 1471.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001749 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1710</obo:IAO_0000119>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001750 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1926</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 18G5.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Giardia Lamblia Killed Protozoa Vaccine (USDA: 18G5.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001751 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1975</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1N11.00</oboInOwl:hasDbXref>
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        <rdfs:label>Neospora Caninum Killed Protozoa Vaccine (USDA: 1N11.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001752 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine (USDA: 18P5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001753 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2086</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 18P5.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine (USDA: 18P5.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001754 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001755 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2080</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 18M1.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Modified Live Virus Vaccine (USDA: 18M1.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001756 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2081</obo:IAO_0000119>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001757 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2082</obo:IAO_0000119>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001758 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2083</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 18M1.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Modified Live Virus Vaccine (USDA: 18M1.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001759 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2084</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 18M1.29</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Modified Live Virus Vaccine (USDA: 18M1.29)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001760 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001760</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies Killed Virus Vaccine (USDA: 1905.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001761 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0001762 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2117</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2117</obo:VO_0001818>
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    <!-- http://purl.obolibrary.org/obo/VO_0001763 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2118</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies Killed Virus Vaccine (USDA: 1905.23)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001764 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2119</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1905.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies Killed Virus Vaccine (USDA: 1905.24)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001765 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2113</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1901.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies Live Canarypox Vector Vaccine (USDA: 1901.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001766 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001766</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2114</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1901.R6</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies Live Canarypox Vector Vaccine (USDA: 1901.R6)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001767 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001767</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1901.R0</oboInOwl:hasDbXref>
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        <rdfs:label>Rabies Live Vaccinia Vector Vaccine (USDA: 1901.R0)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001768 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001769 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001770 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001771 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001774 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001776 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001777 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001778 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001780 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001781 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001781</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1745</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>1745</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
        <oboInOwl:hasDbXref>USDA: 1525.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equine Rhinopneumonitis Killed Virus Vaccine (USDA: 1525.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001782 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001782">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001782</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1741</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1741</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1521.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equine Rhinopneumonitis Modified Live Virus Vaccine (USDA: 1521.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001783 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001783</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1756</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1756</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1E15.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equine Rotavirus Killed Virus Vaccine (USDA: 1E15.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001784 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001784">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001784</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2127</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2127</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1831.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus Equi Live Culture Vaccine (USDA: 1831.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001785 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001785</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1165</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1A15.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Polyomavirus Killed Virus Vaccine (USDA: 1A15.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001786 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001786">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001786</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1701</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1585.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia Psittaci Killed Chlamydia Vaccine (USDA: 1585.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001787 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001787</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1581.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia Psittaci Modified Live Chlamydia Vaccine (USDA: 1581.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001788 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001788">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001473"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001518"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9224"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001788</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2076</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9224"/>
        <obo:VO_0001818>2076</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 18C5.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pacheco&apos;s Disease Killed Virus Vaccine (USDA: 18C5.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001789 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001789">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001789</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1757</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>1757</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
        <oboInOwl:hasDbXref>USDA: 1541.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001790 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001790">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001790</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1758</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1758</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1541.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001791 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001791">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001791</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1759</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1759</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1541.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001792 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001792</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1760</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1760</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1541.03</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.03)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001793 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001793</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1761</obo:IAO_0000119>
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        <obo:VO_0001818>1761</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1541.04</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.04)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001794 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000611"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1927</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>1927</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 19J1.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus Parasuis Avirulent Live Culture Vaccine (USDA: 19J1.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001795 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001795</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:label>Lawsonia Intracellularis Avirulent Live Culture Vaccine (USDA: 10L1.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001796 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001796</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1930</obo:IAO_0000119>
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        <obo:VO_0001818>1930</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 10L1.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lawsonia Intracellularis Avirulent Live Culture Vaccine (USDA: 10L1.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001797 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001797</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 10L1.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lawsonia Intracellularis Avirulent Live Culture Vaccine (USDA: 10L1.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001798 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001798</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2095</obo:IAO_0000119>
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        <obo:VO_0001818>2095</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 19K5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Circovirus Type 2, Killed Virus Vaccine (USDA: 19K5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001799 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001799</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2102</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome Reproductive &amp; Respiratory Form, Modified Live Virus Vaccine (USDA: 19T1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001800 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001800</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 19T1.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome Reproductive &amp; Respiratory Form, Modified Live Virus Vaccine (USDA: 19T1.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001801 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001801</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2101</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 19S5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome Reproductive Form, Killed Virus Vaccine (USDA: 19S5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001802 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2098</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 19Q1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome Reproductive Form, Modified Live Virus Vaccine (USDA: 19Q1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001803 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine (USDA: 19S1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001804 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2100</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 19S1.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine (USDA: 19S1.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001805 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2104</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 19E1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus Modified Live Virus Vaccine (USDA: 19E1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001806 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001806</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies Modified Live Virus Vaccine (USDA: 1891.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001807 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1891.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies Modified Live Virus Vaccine (USDA: 1891.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001808 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001808</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2109</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2109</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1891.R2</oboInOwl:hasDbXref>
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        <rdfs:label>Pseudorabies Modified Live Virus Vaccine (USDA: 1891.R2)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001809 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001809</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2110</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2110</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1891.R4</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies Modified Live Virus Vaccine (USDA: 1891.R4)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001810 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001810</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2134</obo:IAO_0000119>
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        <obo:VO_0001818>2134</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 19A5.2P</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>swine influenza pH1N1, killed virus vaccine (USDA: 19A5.2P)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001811 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001811</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2142</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1961.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Transmissible Gastroenteritis Modified Live Virus Vaccine (USDA: 1961.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001812 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1995.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>West Nile Virus Killed Virus Vaccine (USDA: 1995.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001813 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>West Nile Virus Killed Virus Vaccine (USDA: 1995.22)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001814 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2145</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2145</obo:VO_0001818>
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        <rdfs:label>West Nile Virus Live Canarypox Vector Vaccine (USDA: 1991.R0)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001815 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:label>West Nile Virus Live Flavivirus Chimera Vaccine (USDA: 1991.R1)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001816 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Bluetongue Modified Live Virus Vaccine (USDA: 1061.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001817 -->

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        <obo:VO_0003161>https://www.fda.gov/media/117022/download?attachment</obo:VO_0003161>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Afluria Quadrivalent</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001819 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1K11.00</oboInOwl:hasDbXref>
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        <rdfs:label>Arthrobacter Live Culture Vaccine (USDA: 1K11.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001820 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001821 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001821</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1762</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1762</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Escherichia coli avirulent live culture vaccine (USDA: 1551.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001822 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Escherichia coli avirulent live culture vaccine (USDA: 15R1.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001823 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1763</obo:IAO_0000119>
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        <rdfs:label>Escherichia coli live culture vaccine (USDA: 1551.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001824 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1928</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 17E1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hemorrhagic Enteritis Live Virus Vaccine (USDA: 17E1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001825 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001825</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 19K5.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Circovirus Type 2, Killed Baculovirus Vector Vaccine (USDA: 19K5.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001826 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001826</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2128</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 19A5.12</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine (USDA: 19A5.12)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001827 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2129</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 19A5.22</oboInOwl:hasDbXref>
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    <!-- http://purl.obolibrary.org/obo/VO_0001828 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine (USDA: 19A5.23)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001829 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 19A5.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine (USDA: 19A5.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001830 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001831 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001832 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Mink Distemper-Enteritis Modified Live &amp; Killed Virus Vaccine (USDA: 1679.31)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001833 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Mink Distemper-Enteritis Modified Live &amp; Killed Virus Vaccine-Clostridium Botulinum Type C Bacterin-Toxoid (USDA: 4929.31)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001834 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001835 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001836 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001837 -->

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        <obo:VO_0001818>2895</obo:VO_0001818>
        <obo:VO_0001818>2896</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4955.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C Bacterin-Toxoid (USDA: 4955.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001838 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001838</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2897</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2898</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2897</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4955.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C Bacterin-Toxoid (USDA: 4955.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001839 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001839</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2899</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2900</obo:IAO_0000119>
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        <obo:VO_0001818>2899</obo:VO_0001818>
        <obo:VO_0001818>2900</obo:VO_0001818>
        <obo:VO_0001818>2901</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49A5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 49A5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001840 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2902</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2903</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2904</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2902</obo:VO_0001818>
        <obo:VO_0001818>2903</obo:VO_0001818>
        <obo:VO_0001818>2904</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49A5.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 49A5.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001841 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001841</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1769</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 15D5.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Immunodeficiency-Leukemia Virus Killed Virus Vaccine (USDA: 15D5.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001842 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001842</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1777</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1A69.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1A69.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001843 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001843</metadata:prefixIRI>
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        <obo:VO_0001818>1779</obo:VO_0001818>
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        <obo:VO_0001818>1781</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 15B5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 15B5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001844 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1783</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1784</obo:IAO_0000119>
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        <obo:VO_0001818>1783</obo:VO_0001818>
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        <obo:VO_0001818>1785</obo:VO_0001818>
        <obo:VO_0001818>1786</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 15B5.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001845 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1787</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1788</obo:IAO_0000119>
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        <obo:VO_0001818>1787</obo:VO_0001818>
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        <obo:VO_0001818>1789</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 15B9.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Modified Live &amp; Killed Virus Vaccine (USDA: 15B9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001846 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1791</obo:IAO_0000119>
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        <obo:VO_0001818>1791</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 15B9.21</oboInOwl:hasDbXref>
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        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Modified Live &amp; Killed Virus Vaccine (USDA: 15B9.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001847 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001847</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1795</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1559.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001848 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001848</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001849 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1813</obo:IAO_0000119>
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        <obo:VO_0001818>1810</obo:VO_0001818>
        <obo:VO_0001818>1811</obo:VO_0001818>
        <obo:VO_0001818>1812</obo:VO_0001818>
        <obo:VO_0001818>1813</obo:VO_0001818>
        <obo:VO_0001818>1814</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1559.2C</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live &amp; Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.2C)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001850 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1805</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1806</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1808</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1809</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <obo:VO_0001818>1805</obo:VO_0001818>
        <obo:VO_0001818>1806</obo:VO_0001818>
        <obo:VO_0001818>1807</obo:VO_0001818>
        <obo:VO_0001818>1808</obo:VO_0001818>
        <obo:VO_0001818>1809</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1559.2B</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live &amp; Killed Virus, Modified Live Chlamydia Vaccine (USDA: 1559.2B)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001851 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1821</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1822</obo:IAO_0000119>
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        <obo:VO_0001818>1821</obo:VO_0001818>
        <obo:VO_0001818>1822</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 16F1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16F1.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001852 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001852</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1824</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 16F1.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16F1.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001853 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1839</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 16D5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 16D5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001854 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001854</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 16D5.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 16D5.23)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001855 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1851</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0001856 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001857 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001858 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0001859 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.24)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001860 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001861 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1848</obo:VO_0001818>
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        <obo:VO_0001818>1850</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16D8.21</oboInOwl:hasDbXref>
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        <rdfs:label>Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D8.21)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001862 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1864</obo:VO_0001818>
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    <!-- http://purl.obolibrary.org/obo/VO_0001863 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001864 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 16E6.20</oboInOwl:hasDbXref>
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    <!-- http://purl.obolibrary.org/obo/VO_0001865 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001866 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001867 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E8.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001868 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1878</obo:VO_0001818>
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        <obo:VO_0001818>1882</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0001869 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001870 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001871 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001872 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001873 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001873</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1898</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1899</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <obo:VO_0001818>1898</obo:VO_0001818>
        <obo:VO_0001818>1899</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16C1.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calicivirus Modified Live Virus Vaccine (USDA: 16C1.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001874 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001874</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1900</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1901</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <obo:VO_0001818>1900</obo:VO_0001818>
        <obo:VO_0001818>1901</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16C1.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calicivirus Modified Live Virus Vaccine (USDA: 16C1.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001875 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1174</obo:IAO_0000119>
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        <obo:VO_0001818>1174</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1161.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1161.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001876 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001876</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1176</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1161.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1161.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001877 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001877</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2152</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 45H5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45H5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001878 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001878</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 45H5.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45H5.21)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001879 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2160</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2161</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2163</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2160</obo:VO_0001818>
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        <obo:VO_0001818>2163</obo:VO_0001818>
        <obo:VO_0001818>2164</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4109.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid (USDA: 4109.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001880 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2165</obo:IAO_0000119>
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        <obo:VO_0001818>2165</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4019.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4019.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001881 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4059.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001882 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001882</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2169</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4069.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Hardjo-Pomona Bacterin (USDA: 4069.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001883 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001883</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2171</obo:IAO_0000119>
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        <obo:VO_0001818>2171</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4089.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4089.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001884 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001884</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4089.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001885 -->

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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2187</obo:VO_0001818>
        <obo:VO_0001818>2188</obo:VO_0001818>
        <obo:VO_0001818>2189</obo:VO_0001818>
        <obo:VO_0001818>2190</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4265.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Killed Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin (USDA: 4265.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001886 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001886</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1187</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1188</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1187</obo:VO_0001818>
        <obo:VO_0001818>1188</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1121.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001887 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001887</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1189</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1190</obo:IAO_0000119>
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        <obo:VO_0001818>1189</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1121.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001888 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001888</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1191</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1192</obo:IAO_0000119>
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        <obo:VO_0001818>1191</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1121.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001889 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001889</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1193</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1194</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1193</obo:VO_0001818>
        <obo:VO_0001818>1194</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1121.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001890 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001890</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1195</obo:IAO_0000119>
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        <obo:VO_0001818>1195</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1121.31</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.31)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001891 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001892 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001893 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001894 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001895 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001896 -->

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        <oboInOwl:hasDbXref>USDA: 1071.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001897 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001897">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002343"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001897</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1203</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1204</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1205</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1203</obo:VO_0001818>
        <obo:VO_0001818>1204</obo:VO_0001818>
        <obo:VO_0001818>1205</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1071.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001898 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001898">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002343"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001898</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1206</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1207</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1208</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1206</obo:VO_0001818>
        <obo:VO_0001818>1207</obo:VO_0001818>
        <obo:VO_0001818>1208</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1071.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001899 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001899">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002343"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001899</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1209</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1210</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1211</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1209</obo:VO_0001818>
        <obo:VO_0001818>1210</obo:VO_0001818>
        <obo:VO_0001818>1211</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1071.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001900 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001900">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002344"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001900</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1212</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1213</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1212</obo:VO_0001818>
        <obo:VO_0001818>1213</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 11B5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 11B5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001901 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001901">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002345"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001901</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1224</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1225</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1224</obo:VO_0001818>
        <obo:VO_0001818>1225</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1155.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine (USDA: 1155.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001902 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001902">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002345"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001902</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1226</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1227</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1226</obo:VO_0001818>
        <obo:VO_0001818>1227</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1155.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine (USDA: 1155.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001903 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001903">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002346"/>
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            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000570"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001903</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2195</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2196</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2197</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2198</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2195</obo:VO_0001818>
        <obo:VO_0001818>2196</obo:VO_0001818>
        <obo:VO_0001818>2197</obo:VO_0001818>
        <obo:VO_0001818>2198</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4145.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4145.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001904 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001904">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002346"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001904</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2199</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2200</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2201</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2202</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2199</obo:VO_0001818>
        <obo:VO_0001818>2200</obo:VO_0001818>
        <obo:VO_0001818>2201</obo:VO_0001818>
        <obo:VO_0001818>2202</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4145.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4145.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001905 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001905">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002347"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001905</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2203</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2204</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2205</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2206</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2207</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2203</obo:VO_0001818>
        <obo:VO_0001818>2204</obo:VO_0001818>
        <obo:VO_0001818>2205</obo:VO_0001818>
        <obo:VO_0001818>2206</obo:VO_0001818>
        <obo:VO_0001818>2207</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 43S5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 43S5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001906 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001906">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001906</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2208</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2209</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2210</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2211</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2212</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2213</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2208</obo:VO_0001818>
        <obo:VO_0001818>2209</obo:VO_0001818>
        <obo:VO_0001818>2210</obo:VO_0001818>
        <obo:VO_0001818>2211</obo:VO_0001818>
        <obo:VO_0001818>2212</obo:VO_0001818>
        <obo:VO_0001818>2213</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 43T5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid (USDA: 43T5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001907 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001907">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002349"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001907</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2214</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2215</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2216</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2214</obo:VO_0001818>
        <obo:VO_0001818>2215</obo:VO_0001818>
        <obo:VO_0001818>2216</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4335.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4335.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001908 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001908">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001908</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2217</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2218</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2219</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        <obo:VO_0001818>2217</obo:VO_0001818>
        <obo:VO_0001818>2218</obo:VO_0001818>
        <obo:VO_0001818>2219</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4336.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4336.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001909 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001909">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002345"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001909</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1214</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1215</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1214</obo:VO_0001818>
        <obo:VO_0001818>1215</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1151.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001910 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001910">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002345"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001910</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1216</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1217</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1216</obo:VO_0001818>
        <obo:VO_0001818>1217</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1151.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001911 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001911">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002345"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001911</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1218</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1219</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1218</obo:VO_0001818>
        <obo:VO_0001818>1219</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1151.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001912 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001912">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002345"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001912</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1220</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1221</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1220</obo:VO_0001818>
        <obo:VO_0001818>1221</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1151.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001913 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001913">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002345"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001913</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1222</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1223</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1222</obo:VO_0001818>
        <obo:VO_0001818>1223</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:hasDbXref>USDA: 1151.26</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.26)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001914">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002346"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001914</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2191</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2192</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2193</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2194</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2191</obo:VO_0001818>
        <obo:VO_0001818>2192</obo:VO_0001818>
        <obo:VO_0001818>2193</obo:VO_0001818>
        <obo:VO_0001818>2194</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4141.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4141.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001915 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001915">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002349"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001915</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2220</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2221</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2222</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2220</obo:VO_0001818>
        <obo:VO_0001818>2221</obo:VO_0001818>
        <obo:VO_0001818>2222</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4339.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4339.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001916 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001916">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002350"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000890"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001916</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2223</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2224</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2225</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2223</obo:VO_0001818>
        <obo:VO_0001818>2224</obo:VO_0001818>
        <obo:VO_0001818>2225</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4359.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4359.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001917 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001917">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002351"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000701"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001917</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2226</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2227</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2228</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2226</obo:VO_0001818>
        <obo:VO_0001818>2227</obo:VO_0001818>
        <obo:VO_0001818>2228</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4399.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Hardjo-Pomona Bacterin (USDA: 4399.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001918 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001918">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002352"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001918</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2229</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2230</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2231</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2229</obo:VO_0001818>
        <obo:VO_0001818>2230</obo:VO_0001818>
        <obo:VO_0001818>2231</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4389.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4389.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001919 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001919">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001919</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2232</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2233</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2234</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2232</obo:VO_0001818>
        <obo:VO_0001818>2233</obo:VO_0001818>
        <obo:VO_0001818>2234</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4389.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4389.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001920 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001920">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001920</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2235</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2236</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2237</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2235</obo:VO_0001818>
        <obo:VO_0001818>2236</obo:VO_0001818>
        <obo:VO_0001818>2237</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4389.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4389.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001921 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001921">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002353"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001921</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1252</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1253</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1254</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1252</obo:VO_0001818>
        <obo:VO_0001818>1253</obo:VO_0001818>
        <obo:VO_0001818>1254</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Killed Virus Vaccine (USDA: 1175.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001922 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2252</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2253</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2254</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2255</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2255</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4435.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4435.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001923 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1228</obo:IAO_0000119>
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        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001924 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1232</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 1171.20</oboInOwl:hasDbXref>
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        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001925 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.22)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001926 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001927 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001928 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001929 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001930 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0001931 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001931</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2238</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2239</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2240</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2241</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2238</obo:VO_0001818>
        <obo:VO_0001818>2239</obo:VO_0001818>
        <obo:VO_0001818>2240</obo:VO_0001818>
        <obo:VO_0001818>2241</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4560.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4560.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001932 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001932">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002354"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001932</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2242</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2243</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2244</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2245</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2242</obo:VO_0001818>
        <obo:VO_0001818>2243</obo:VO_0001818>
        <obo:VO_0001818>2244</obo:VO_0001818>
        <obo:VO_0001818>2245</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4560.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4560.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001933 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001933">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002490"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000901"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001933</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2246</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2247</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2248</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2249</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2250</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2251</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2246</obo:VO_0001818>
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        <obo:VO_0001818>2248</obo:VO_0001818>
        <obo:VO_0001818>2249</obo:VO_0001818>
        <obo:VO_0001818>2250</obo:VO_0001818>
        <obo:VO_0001818>2251</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4489.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Haemophilus somnus-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4489.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001934 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001934">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002355"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000890"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001934</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2256</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2257</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2258</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2259</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2256</obo:VO_0001818>
        <obo:VO_0001818>2257</obo:VO_0001818>
        <obo:VO_0001818>2258</obo:VO_0001818>
        <obo:VO_0001818>2259</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4439.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4439.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001935 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001935">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002355"/>
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        <rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001935</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2260</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2261</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2262</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2263</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2260</obo:VO_0001818>
        <obo:VO_0001818>2261</obo:VO_0001818>
        <obo:VO_0001818>2262</obo:VO_0001818>
        <obo:VO_0001818>2263</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4439.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4439.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001936 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001936">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002356"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001936</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2264</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2265</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2266</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2267</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2264</obo:VO_0001818>
        <obo:VO_0001818>2265</obo:VO_0001818>
        <obo:VO_0001818>2266</obo:VO_0001818>
        <obo:VO_0001818>2267</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4479.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4479.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001937 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001937">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002488"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001937</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2268</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2269</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2270</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2271</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2268</obo:VO_0001818>
        <obo:VO_0001818>2269</obo:VO_0001818>
        <obo:VO_0001818>2270</obo:VO_0001818>
        <obo:VO_0001818>2271</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4509.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4509.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001938 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001938</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2486</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2487</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2489</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2486</obo:VO_0001818>
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        <obo:VO_0001818>2488</obo:VO_0001818>
        <obo:VO_0001818>2489</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44A5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Mannheimia Haemolytica Bacterin (USDA: 44A5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001939 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001939</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1255</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1256</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1257</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1258</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1255</obo:VO_0001818>
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        <obo:VO_0001818>1257</obo:VO_0001818>
        <obo:VO_0001818>1258</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1181.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001940 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001940</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1259</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1260</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1262</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1259</obo:VO_0001818>
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        <obo:VO_0001818>1261</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1181.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001941 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001941">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001941</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1263</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 1181.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001942 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001942">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001942</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1267</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 1181.22</oboInOwl:hasDbXref>
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        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001943 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001943</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1271</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1271</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1181.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001944 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001944">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000901"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001944</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1275</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1276</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1277</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1278</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1275</obo:VO_0001818>
        <obo:VO_0001818>1276</obo:VO_0001818>
        <obo:VO_0001818>1277</obo:VO_0001818>
        <obo:VO_0001818>1278</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1181.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001945 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001945">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001945</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1279</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1280</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1281</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1282</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1279</obo:VO_0001818>
        <obo:VO_0001818>1280</obo:VO_0001818>
        <obo:VO_0001818>1281</obo:VO_0001818>
        <obo:VO_0001818>1282</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1181.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001946 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001946">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001946</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1283</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1284</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1285</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1286</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1283</obo:VO_0001818>
        <obo:VO_0001818>1284</obo:VO_0001818>
        <obo:VO_0001818>1285</obo:VO_0001818>
        <obo:VO_0001818>1286</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1181.26</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.26)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001947 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001947">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001947</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1287</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1288</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1289</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1290</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1287</obo:VO_0001818>
        <obo:VO_0001818>1288</obo:VO_0001818>
        <obo:VO_0001818>1289</obo:VO_0001818>
        <obo:VO_0001818>1290</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1181.28</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.28)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001948 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001948">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001948</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1291</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1292</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1293</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1294</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1291</obo:VO_0001818>
        <obo:VO_0001818>1292</obo:VO_0001818>
        <obo:VO_0001818>1293</obo:VO_0001818>
        <obo:VO_0001818>1294</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1181.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001949 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001949">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001949</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1295</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1296</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1297</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1298</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1295</obo:VO_0001818>
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        <obo:VO_0001818>1297</obo:VO_0001818>
        <obo:VO_0001818>1298</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1185.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1185.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001950 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1299</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1299</obo:VO_0001818>
        <obo:VO_0001818>1300</obo:VO_0001818>
        <obo:VO_0001818>1301</obo:VO_0001818>
        <obo:VO_0001818>1302</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1185.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1185.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001951 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001951</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2277</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2278</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2277</obo:VO_0001818>
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        <obo:VO_0001818>2281</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44M5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001952 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002359"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001952</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 44M5.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44M5.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001953 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001953</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 44B5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001954 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001954</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 44B6.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B6.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001955 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001955</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2325</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2327</obo:VO_0001818>
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        <obo:VO_0001818>2329</obo:VO_0001818>
        <obo:VO_0001818>2330</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44B6.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B6.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001956 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001956">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000570"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001956</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2343</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2344</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2345</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2346</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2343</obo:VO_0001818>
        <obo:VO_0001818>2344</obo:VO_0001818>
        <obo:VO_0001818>2345</obo:VO_0001818>
        <obo:VO_0001818>2346</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44C5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001957 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002361"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001957</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2347</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2348</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2349</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2350</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2347</obo:VO_0001818>
        <obo:VO_0001818>2348</obo:VO_0001818>
        <obo:VO_0001818>2349</obo:VO_0001818>
        <obo:VO_0001818>2350</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44C7.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C7.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001958 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001958">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002361"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001958</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2367</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2368</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2369</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2370</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2367</obo:VO_0001818>
        <obo:VO_0001818>2368</obo:VO_0001818>
        <obo:VO_0001818>2369</obo:VO_0001818>
        <obo:VO_0001818>2370</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44D5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44D5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001959 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001959">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002362"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001959</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2375</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2376</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2377</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2378</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2379</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2375</obo:VO_0001818>
        <obo:VO_0001818>2376</obo:VO_0001818>
        <obo:VO_0001818>2377</obo:VO_0001818>
        <obo:VO_0001818>2378</obo:VO_0001818>
        <obo:VO_0001818>2379</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44D7.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D7.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001960 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001960">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002362"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001960</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2380</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2381</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2382</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2383</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2384</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2380</obo:VO_0001818>
        <obo:VO_0001818>2381</obo:VO_0001818>
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        <obo:VO_0001818>2383</obo:VO_0001818>
        <obo:VO_0001818>2384</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44D7.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D7.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001961 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001961">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001961</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2405</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2406</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2405</obo:VO_0001818>
        <obo:VO_0001818>2406</obo:VO_0001818>
        <obo:VO_0001818>2407</obo:VO_0001818>
        <obo:VO_0001818>2408</obo:VO_0001818>
        <obo:VO_0001818>2409</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4477.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica Bacterin (USDA: 4477.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001962 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001962</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2426</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2427</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2428</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2429</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2426</obo:VO_0001818>
        <obo:VO_0001818>2427</obo:VO_0001818>
        <obo:VO_0001818>2428</obo:VO_0001818>
        <obo:VO_0001818>2429</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4465.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4465.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001963 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2430</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2431</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2432</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4465.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4465.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001964 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2434</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2435</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 4465.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4465.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001965 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001965">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001965</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2438</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 4466.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4466.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001966 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001966</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001967 -->

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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2482</obo:VO_0001818>
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        <obo:VO_0001818>2484</obo:VO_0001818>
        <obo:VO_0001818>2485</obo:VO_0001818>
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        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona-Mannheimia Haemolytica Bacterin (USDA: 4475.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001968 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1303</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0001969 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1307</obo:IAO_0000119>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001970 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1311</obo:IAO_0000119>
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        <obo:VO_0001818>1311</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1187.22</oboInOwl:hasDbXref>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001971 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001972 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001972</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0001973 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1323</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1324</obo:IAO_0000119>
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        <obo:VO_0001818>1323</obo:VO_0001818>
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        <obo:VO_0001818>1325</obo:VO_0001818>
        <obo:VO_0001818>1326</obo:VO_0001818>
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        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live &amp; Killed Virus Vaccine (USDA: 1189.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001974 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1327</obo:IAO_0000119>
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        <obo:VO_0001818>1327</obo:VO_0001818>
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        <obo:VO_0001818>1330</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1189.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live &amp; Killed Virus Vaccine (USDA: 1189.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001975 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0001976 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 44B9.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live &amp; Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B9.22)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001977 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001977</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 44F9.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0001978 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2455</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2456</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2457</obo:IAO_0000119>
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        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001979 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2459</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2461</obo:IAO_0000119>
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        <obo:VO_0001818>2458</obo:VO_0001818>
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        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.22)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001980 -->

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        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.25)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001981 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001982 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001982</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0001983 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2298</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2299</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2295</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001984 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2301</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 44B1.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001985 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 44B1.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001986 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001986</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001987 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001988 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001989 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001989">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002361"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001989</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2363</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2364</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2365</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2366</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2363</obo:VO_0001818>
        <obo:VO_0001818>2364</obo:VO_0001818>
        <obo:VO_0001818>2365</obo:VO_0001818>
        <obo:VO_0001818>2366</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44C9.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001990 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001990">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002362"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001990</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2385</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2386</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2387</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2388</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2389</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2385</obo:VO_0001818>
        <obo:VO_0001818>2386</obo:VO_0001818>
        <obo:VO_0001818>2387</obo:VO_0001818>
        <obo:VO_0001818>2388</obo:VO_0001818>
        <obo:VO_0001818>2389</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44D9.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001991 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001991">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002362"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001991</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2390</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2391</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2392</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2393</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2394</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2390</obo:VO_0001818>
        <obo:VO_0001818>2391</obo:VO_0001818>
        <obo:VO_0001818>2392</obo:VO_0001818>
        <obo:VO_0001818>2393</obo:VO_0001818>
        <obo:VO_0001818>2394</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44D9.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001992 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001992">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001992</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2395</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2396</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2397</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2398</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2399</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2395</obo:VO_0001818>
        <obo:VO_0001818>2396</obo:VO_0001818>
        <obo:VO_0001818>2397</obo:VO_0001818>
        <obo:VO_0001818>2398</obo:VO_0001818>
        <obo:VO_0001818>2399</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44D9.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001993 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001993">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001993</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2400</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2401</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2402</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2403</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2404</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2400</obo:VO_0001818>
        <obo:VO_0001818>2401</obo:VO_0001818>
        <obo:VO_0001818>2402</obo:VO_0001818>
        <obo:VO_0001818>2403</obo:VO_0001818>
        <obo:VO_0001818>2404</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 44D9.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001994 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0001994">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001994</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2410</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2411</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2412</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2413</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2410</obo:VO_0001818>
        <obo:VO_0001818>2411</obo:VO_0001818>
        <obo:VO_0001818>2412</obo:VO_0001818>
        <obo:VO_0001818>2413</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4461.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001995 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001995</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2414</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2415</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2416</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2417</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2414</obo:VO_0001818>
        <obo:VO_0001818>2415</obo:VO_0001818>
        <obo:VO_0001818>2416</obo:VO_0001818>
        <obo:VO_0001818>2417</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4461.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001996 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001996</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2418</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2419</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2420</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2421</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2418</obo:VO_0001818>
        <obo:VO_0001818>2419</obo:VO_0001818>
        <obo:VO_0001818>2420</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4461.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001997 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001997</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2422</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2423</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2424</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2425</obo:IAO_0000119>
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        <obo:VO_0001818>2424</obo:VO_0001818>
        <obo:VO_0001818>2425</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4461.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001998 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001998</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2446</obo:IAO_0000119>
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        <obo:VO_0001818>2446</obo:VO_0001818>
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        <obo:VO_0001818>2448</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4469.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001999 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0001999</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 4469.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.01)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002000 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002000</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2462</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2463</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2464</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2465</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2462</obo:VO_0001818>
        <obo:VO_0001818>2463</obo:VO_0001818>
        <obo:VO_0001818>2464</obo:VO_0001818>
        <obo:VO_0001818>2465</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4469.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002364"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002001</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2466</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2467</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2468</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2469</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2466</obo:VO_0001818>
        <obo:VO_0001818>2467</obo:VO_0001818>
        <obo:VO_0001818>2468</obo:VO_0001818>
        <obo:VO_0001818>2469</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4469.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002364"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002002</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2474</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2475</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2476</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2477</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2474</obo:VO_0001818>
        <obo:VO_0001818>2475</obo:VO_0001818>
        <obo:VO_0001818>2476</obo:VO_0001818>
        <obo:VO_0001818>2477</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4469.26</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.26)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002368"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002003</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2272</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2273</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2274</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2275</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2276</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2272</obo:VO_0001818>
        <obo:VO_0001818>2273</obo:VO_0001818>
        <obo:VO_0001818>2274</obo:VO_0001818>
        <obo:VO_0001818>2275</obo:VO_0001818>
        <obo:VO_0001818>2276</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4L49.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Hardjo Bacterin (USDA: 4L49.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002369"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002004</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2490</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2491</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2492</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2493</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2490</obo:VO_0001818>
        <obo:VO_0001818>2491</obo:VO_0001818>
        <obo:VO_0001818>2492</obo:VO_0001818>
        <obo:VO_0001818>2493</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4X49.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica Toxoid (USDA: 4X49.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002369"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002005</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2494</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2495</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2496</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2497</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2494</obo:VO_0001818>
        <obo:VO_0001818>2495</obo:VO_0001818>
        <obo:VO_0001818>2496</obo:VO_0001818>
        <obo:VO_0001818>2497</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4X49.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica Toxoid (USDA: 4X49.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002370"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002006</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2498</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2499</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2500</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2501</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2502</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2498</obo:VO_0001818>
        <obo:VO_0001818>2499</obo:VO_0001818>
        <obo:VO_0001818>2500</obo:VO_0001818>
        <obo:VO_0001818>2501</obo:VO_0001818>
        <obo:VO_0001818>2502</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 45B9.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45B9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002370"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002007</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2503</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2504</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2505</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2506</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2507</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2503</obo:VO_0001818>
        <obo:VO_0001818>2504</obo:VO_0001818>
        <obo:VO_0001818>2505</obo:VO_0001818>
        <obo:VO_0001818>2506</obo:VO_0001818>
        <obo:VO_0001818>2507</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 45B9.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45B9.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002008">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002371"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002008</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1331</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1332</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1333</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1334</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1335</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1336</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1331</obo:VO_0001818>
        <obo:VO_0001818>1332</obo:VO_0001818>
        <obo:VO_0001818>1333</obo:VO_0001818>
        <obo:VO_0001818>1334</obo:VO_0001818>
        <obo:VO_0001818>1335</obo:VO_0001818>
        <obo:VO_0001818>1336</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 11A8.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus-Mannheimia Haemolytica-Pasteurella Multocida Modified Live Virus, Avirulent Live Culture Vaccine (USDA: 11A8.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002372"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002009</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1346</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1347</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1348</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1346</obo:VO_0001818>
        <obo:VO_0001818>1347</obo:VO_0001818>
        <obo:VO_0001818>1348</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 11A5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 11A5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002010">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002372"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000057"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002010</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1337</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1338</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1339</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1337</obo:VO_0001818>
        <obo:VO_0001818>1338</obo:VO_0001818>
        <obo:VO_0001818>1339</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 11A1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 11A1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002372"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002011</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1340</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1341</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1342</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1340</obo:VO_0001818>
        <obo:VO_0001818>1341</obo:VO_0001818>
        <obo:VO_0001818>1342</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 11A1.26</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 11A1.26)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002012">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002372"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002012</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1343</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1344</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1345</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1343</obo:VO_0001818>
        <obo:VO_0001818>1344</obo:VO_0001818>
        <obo:VO_0001818>1345</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 11A1.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 11A1.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002373"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000057"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002013</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2508</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2509</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2510</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2511</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2508</obo:VO_0001818>
        <obo:VO_0001818>2509</obo:VO_0001818>
        <obo:VO_0001818>2510</obo:VO_0001818>
        <obo:VO_0001818>2511</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4367.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4367.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002373"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002014</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2512</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2513</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2514</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2515</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2512</obo:VO_0001818>
        <obo:VO_0001818>2513</obo:VO_0001818>
        <obo:VO_0001818>2514</obo:VO_0001818>
        <obo:VO_0001818>2515</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4367.26</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4367.26)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002015">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002373"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000057"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002015</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2516</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2517</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2518</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2519</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2516</obo:VO_0001818>
        <obo:VO_0001818>2517</obo:VO_0001818>
        <obo:VO_0001818>2518</obo:VO_0001818>
        <obo:VO_0001818>2519</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4367.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4367.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002374"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000570"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002016</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1350</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1350</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1935.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Modified Killed Virus Vaccine (USDA: 1935.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002374"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002017</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1349</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1349</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1931.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Modified Live Virus Vaccine (USDA: 1931.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000974"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002375"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002018</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2520</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2521</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2522</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2523</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2520</obo:VO_0001818>
        <obo:VO_0001818>2521</obo:VO_0001818>
        <obo:VO_0001818>2522</obo:VO_0001818>
        <obo:VO_0001818>2523</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4570.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 4570.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000974"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002375"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002019</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2524</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2525</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2526</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2527</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2524</obo:VO_0001818>
        <obo:VO_0001818>2525</obo:VO_0001818>
        <obo:VO_0001818>2526</obo:VO_0001818>
        <obo:VO_0001818>2527</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4570.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 4570.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000974"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002376"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002020</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2528</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2529</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2530</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2531</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2528</obo:VO_0001818>
        <obo:VO_0001818>2529</obo:VO_0001818>
        <obo:VO_0001818>2530</obo:VO_0001818>
        <obo:VO_0001818>2531</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4575.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Clostridium Perfringens Types C &amp; D-Escherichia Coli Bacterin-Toxoid (USDA: 4575.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002021">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000974"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002377"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002021</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2532</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2533</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2534</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2532</obo:VO_0001818>
        <obo:VO_0001818>2533</obo:VO_0001818>
        <obo:VO_0001818>2534</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4585.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Escherichia Coli Bacterin (USDA: 4585.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000974"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002377"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002022</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2535</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2536</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2537</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2535</obo:VO_0001818>
        <obo:VO_0001818>2536</obo:VO_0001818>
        <obo:VO_0001818>2537</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4585.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Escherichia Coli Bacterin (USDA: 4585.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002023 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002023">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002378"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002023</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2538</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2539</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2540</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2538</obo:VO_0001818>
        <obo:VO_0001818>2539</obo:VO_0001818>
        <obo:VO_0001818>2540</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 45B5.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 45B5.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002024">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002379"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000058"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002024</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2541</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2542</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2543</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2544</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2541</obo:VO_0001818>
        <obo:VO_0001818>2542</obo:VO_0001818>
        <obo:VO_0001818>2543</obo:VO_0001818>
        <obo:VO_0001818>2544</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4C95.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 4C95.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002025 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002025">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002380"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002025</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2545</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2546</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2545</obo:VO_0001818>
        <obo:VO_0001818>2546</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4595.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4595.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002026</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2547</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2548</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2547</obo:VO_0001818>
        <obo:VO_0001818>2548</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4595.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4595.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002381"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000890"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002027</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2549</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2550</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2549</obo:VO_0001818>
        <obo:VO_0001818>2550</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4599.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4599.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002028">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002486"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002028</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1359</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1360</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>1359</obo:VO_0001818>
        <obo:VO_0001818>1360</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12A5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 12A5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002029</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1932</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1933</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1932</obo:VO_0001818>
        <obo:VO_0001818>1933</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
        <oboInOwl:hasDbXref>USDA: 1861.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mannheimia Haemolytica-Pasteurella Multocida Avirulent Live Culture Vaccine (USDA: 1861.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002030">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002328"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002030</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1143</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1144</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1145</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0001818>1143</obo:VO_0001818>
        <obo:VO_0001818>1144</obo:VO_0001818>
        <obo:VO_0001818>1145</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <oboInOwl:hasDbXref>USDA:1D61.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Encephalomyelitis-Fowl Pox-Mycoplasma Gallisepticum Live Fowl Pox Vector, Live Virus Vaccine (USDA:1D61.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002031">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002382"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002031</metadata:prefixIRI>
        <obo:IAO_0000116>JZ: it may be same as term VO:0002048, USDA: 12C2.50, current USDA numbers are not correct since manufacturer is not same. </obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1437</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1438</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1437</obo:VO_0001818>
        <obo:VO_0001818>1438</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Variant, Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: )</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002032">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001178"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002329"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003143"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002032</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1160</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1161</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0001818>1160</obo:VO_0001818>
        <obo:VO_0001818>1161</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <oboInOwl:hasDbXref>USDA: 1061.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian influenza-Fowl Pox H5 Subtype, Live Fowl Pox Vector Vaccine (USDA: 1061.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002326"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002033</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1130</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1131</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0001818>1130</obo:VO_0001818>
        <obo:VO_0001818>1131</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <oboInOwl:hasDbXref>USDA: 10M1.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.10 )</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002326"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002034</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1132</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1133</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0001818>1132</obo:VO_0001818>
        <obo:VO_0001818>1133</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <oboInOwl:hasDbXref>USDA: 10M1.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002035">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002326"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002035</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1134</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1135</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0001818>1134</obo:VO_0001818>
        <obo:VO_0001818>1135</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <oboInOwl:hasDbXref>USDA: 10M1.13</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.13)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002326"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
            </owl:Restriction>
        </rdfs:subClassOf>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1136</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1137</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0001818>1136</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.14)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002037 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1138</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1139</obo:IAO_0000119>
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        <obo:VO_0001818>1138</obo:VO_0001818>
        <obo:VO_0001818>1139</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 10M1.40</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.40)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002038 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1140</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1141</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1142</obo:IAO_0000119>
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        <rdfs:label>Avian Encephalomyelitis-Fowl Pox-Laryngotracheitis Live Virus, Live Fowl Pox Vector Vaccine (USDA: 10S1.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002039 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002039</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1128</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian Encephalomyelitis-Chicken Anemia Virus-Fowl Pox C155Live and Modified Live C212Virus Vaccine (USDA: 10T1.40)+C433</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002040 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002040</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotypes 1 &amp; 2 &amp; 3, Live Virus, Live Marek&apos;s Disease Vector Vaccine (USDA: 1281.R0)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002041 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1281.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotypes 1 &amp; 3, Live Virus, Live Marek&apos;s Disease Vector Vaccine (USDA: 1281.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002042">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002382"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002042</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1419</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1420</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1419</obo:VO_0001818>
        <obo:VO_0001818>1420</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1282.50</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Variant, Serotype 3, Live Virus Vaccine (USDA: 1282.50)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002043">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002382"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002043</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1421</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1422</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1421</obo:VO_0001818>
        <obo:VO_0001818>1422</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1288.42</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotype 3, Live Virus Vaccine (USDA: 1288.42)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002044">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002382"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002044</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1423</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1424</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1423</obo:VO_0001818>
        <obo:VO_0001818>1424</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1288.43</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 1288.43)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002045">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002045</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1425</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1426</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1425</obo:VO_0001818>
        <obo:VO_0001818>1426</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1288.44</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 1288.44)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002046">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002046</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1427</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1428</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1427</obo:VO_0001818>
        <obo:VO_0001818>1428</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1288.45</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 1288.45)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002047</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1429</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1430</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1429</obo:VO_0001818>
        <obo:VO_0001818>1430</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1288.4A</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotype 3, Live Virus Vaccine (USDA: 1288.4A)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002048 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002048">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002048</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1431</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1432</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1431</obo:VO_0001818>
        <obo:VO_0001818>1432</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12C2.50</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Variant, Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 12C2.50)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002049">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002049</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1433</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1434</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1433</obo:VO_0001818>
        <obo:VO_0001818>1434</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12C2.51</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Variant, Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 12C2.51)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002050</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1435</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1436</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1435</obo:VO_0001818>
        <obo:VO_0001818>1436</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12C2.52</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Variant Strain, Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 12C2.52)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002051</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1439</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1440</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1439</obo:VO_0001818>
        <obo:VO_0001818>1440</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12C8.40</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Standard &amp; Variant, Serotype 3, Live Virus Vaccine (USDA: 12C8.40)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002052 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002052">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002052</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1441</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1442</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1441</obo:VO_0001818>
        <obo:VO_0001818>1442</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12C8.42</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Standard &amp; Variant, Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 12C8.42)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002053 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002053">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002053</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1443</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1444</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1443</obo:VO_0001818>
        <obo:VO_0001818>1444</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12C8.43</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Standard &amp; Variant, Serotype 3, Live Virus Vaccine (USDA: 12C8.43)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002054</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1445</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1446</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1445</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 12C8.44</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Standard &amp; Variant, Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 12C8.44)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002055 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002055</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1539</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1540</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1539</obo:VO_0001818>
        <obo:VO_0001818>1540</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12D5.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12D5.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002056 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002056">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002056</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1541</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1542</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1541</obo:VO_0001818>
        <obo:VO_0001818>1542</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12D5.02</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Reovirus Killed Virus Vaccine (USDA: 12D5.02)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002057 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002057">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002057</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1543</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1544</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1543</obo:VO_0001818>
        <obo:VO_0001818>1544</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12D5.03</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12D5.03)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002058 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002058">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002058</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1545</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1546</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1545</obo:VO_0001818>
        <obo:VO_0001818>1546</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12D5.04</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12D5.04)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002059 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002059</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1547</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1548</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1547</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 12D5.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12D5.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002060">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002060</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1465</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1466</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1467</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1465</obo:VO_0001818>
        <obo:VO_0001818>1466</obo:VO_0001818>
        <obo:VO_0001818>1467</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12D5.45</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis Standard &amp; Variant, Mass &amp; Ark Types, Killed Virus Vaccine (USDA: 12D5.45)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002061">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002061</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1549</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1550</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1549</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 12D5.E0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12D5.E0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002062 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002062</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1551</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1552</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1551</obo:VO_0001818>
        <obo:VO_0001818>1552</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12D5.F0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12D5.F0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002063 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002063</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1553</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1554</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1553</obo:VO_0001818>
        <obo:VO_0001818>1554</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12D5.F1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12D5.F1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002064 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002064</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1555</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1556</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1555</obo:VO_0001818>
        <obo:VO_0001818>1556</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12D5.T0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12D5.T0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002065 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002065</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1457</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1458</obo:IAO_0000119>
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        <obo:VO_0001818>1457</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 12G5.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease Killed Virus Vaccine (USDA: 12G5.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002066 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002066</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1459</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1460</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1459</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 12G5.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease Killed Virus Vaccine (USDA: 12G5.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002067 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002067</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1461</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1462</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1461</obo:VO_0001818>
        <obo:VO_0001818>1462</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12G5.42</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease Standard &amp; Variant, Killed Virus Vaccine (USDA: 12G5.42)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002068 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002068</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1463</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1464</obo:IAO_0000119>
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        <obo:VO_0001818>1463</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 12G5.43</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease Killed Virus Vaccine (USDA: 12G5.43)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002069 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002069</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1468</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1469</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1470</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1468</obo:VO_0001818>
        <obo:VO_0001818>1469</obo:VO_0001818>
        <obo:VO_0001818>1470</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12H1.4M</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis B1 Type, B1 Strain, Mass &amp; Ark Types, Live Virus Vaccine (USDA: 12H1.4M)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002070 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002070</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1471</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1472</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1473</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1471</obo:VO_0001818>
        <obo:VO_0001818>1472</obo:VO_0001818>
        <obo:VO_0001818>1473</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12H1.67</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis B1 Type, B1 Strain, Mass &amp; Ark Types, Live Virus Vaccine (USDA: 12H1.67)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002071 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002071</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1474</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1475</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1476</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1474</obo:VO_0001818>
        <obo:VO_0001818>1475</obo:VO_0001818>
        <obo:VO_0001818>1476</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12J5.40</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 12J5.40)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002072 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002072</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1477</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1478</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1479</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1477</obo:VO_0001818>
        <obo:VO_0001818>1478</obo:VO_0001818>
        <obo:VO_0001818>1479</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12J5.43</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 12J5.43)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002073 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002073</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1480</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1481</obo:IAO_0000119>
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        <obo:VO_0001818>1480</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 12J5.61</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis Standard &amp; Variant, Mass Type, Killed Virus Vaccine (USDA: 12J5.61)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002074 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002074</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1483</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1484</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 12J5.62</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 12J5.62)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002075 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002075</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1486</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1488</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1486</obo:VO_0001818>
        <obo:VO_0001818>1487</obo:VO_0001818>
        <obo:VO_0001818>1488</obo:VO_0001818>
        <obo:VO_0001818>1489</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12M5.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard &amp; Variant, Mass Type, Killed Virus Vaccine (USDA: 12M5.00)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002076 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002076</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1490</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1491</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1492</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1493</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1490</obo:VO_0001818>
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        <obo:VO_0001818>1492</obo:VO_0001818>
        <obo:VO_0001818>1493</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12M5.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard &amp; Variant, Mass Type, Killed Virus Vaccine (USDA: 12M5.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002077 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002077</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1494</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1495</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1496</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1497</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1494</obo:VO_0001818>
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        <obo:VO_0001818>1496</obo:VO_0001818>
        <obo:VO_0001818>1497</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12M5.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002078 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002078</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1498</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1499</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1500</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1501</obo:IAO_0000119>
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        <obo:VO_0001818>1498</obo:VO_0001818>
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        <obo:VO_0001818>1500</obo:VO_0001818>
        <obo:VO_0001818>1501</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12M5.40</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Killed Virus Vaccine (USDA: 12M5.40)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002079 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002079</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1502</obo:IAO_0000119>
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        <obo:VO_0001818>1502</obo:VO_0001818>
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        <obo:VO_0001818>1505</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12M5.41</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard &amp; Variant, Mass &amp; Ark Types, Killed Virus Vaccine (USDA: 12M5.41)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002080</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1506</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1507</obo:IAO_0000119>
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        <obo:VO_0001818>1508</obo:VO_0001818>
        <obo:VO_0001818>1509</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12M5.42</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard &amp; Variant, Mass &amp; Ark Types, Killed Virus Vaccine (USDA: 12M5.42)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002081 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002081</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.43)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002082 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002082</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1514</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1515</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1516</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1517</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1514</obo:VO_0001818>
        <obo:VO_0001818>1515</obo:VO_0001818>
        <obo:VO_0001818>1516</obo:VO_0001818>
        <obo:VO_0001818>1517</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12M5.50</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.50)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002083 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002083</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1518</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1519</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1520</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1521</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1518</obo:VO_0001818>
        <obo:VO_0001818>1519</obo:VO_0001818>
        <obo:VO_0001818>1520</obo:VO_0001818>
        <obo:VO_0001818>1521</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12M5.90</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.90)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002084 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002084</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1522</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1523</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1524</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1525</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1522</obo:VO_0001818>
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        <obo:VO_0001818>1524</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 12M5.91</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.91)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002085 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002085</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1526</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1527</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1528</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1529</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1526</obo:VO_0001818>
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        <obo:VO_0001818>1528</obo:VO_0001818>
        <obo:VO_0001818>1529</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12M5.E0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard &amp; Variant, Mass Type, Killed Virus Vaccine (USDA: 12M5.E0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002086 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002086</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 12P5.40</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12P5.40)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002087 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002087">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002087</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1533</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1534</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 12P5.41</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12P5.41)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002088 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002088</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1536</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1537</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1538</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1536</obo:VO_0001818>
        <obo:VO_0001818>1537</obo:VO_0001818>
        <obo:VO_0001818>1538</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12P5.E0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Reovirus Standard &amp; Variant, Killed Virus Vaccine (USDA: 12P5.E0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002089 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002089">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002386"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002089</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1558</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1559</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1560</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1558</obo:VO_0001818>
        <obo:VO_0001818>1559</obo:VO_0001818>
        <obo:VO_0001818>1560</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 12X1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Modified Live Virus &amp; Avirulent Live Culture Vaccine (USDA: 12X1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002090 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002090">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002090</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1657</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1658</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1659</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1657</obo:VO_0001818>
        <obo:VO_0001818>1658</obo:VO_0001818>
        <obo:VO_0001818>1659</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1331.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002091 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002091">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002091</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1660</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1661</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1662</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1660</obo:VO_0001818>
        <obo:VO_0001818>1661</obo:VO_0001818>
        <obo:VO_0001818>1662</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1331.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002092 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002092">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002092</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1663</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1664</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1665</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1663</obo:VO_0001818>
        <obo:VO_0001818>1664</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1331.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.27)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002093">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002093</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1666</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1667</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1668</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1666</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1331.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.30)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002094 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002094</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1669</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1670</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1671</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1669</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1331.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus, Canarypox Vector Vaccine (USDA: 1331.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002095 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002406"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002095</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1605</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1606</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1607</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1608</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1605</obo:VO_0001818>
        <obo:VO_0001818>1606</obo:VO_0001818>
        <obo:VO_0001818>1607</obo:VO_0001818>
        <obo:VO_0001818>1608</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1341.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Measles-Parainfluenza Modified Live Virus Vaccine (USDA: 1341.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002096 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002416"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002096</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1685</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1686</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1685</obo:VO_0001818>
        <obo:VO_0001818>1686</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1351.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Measles Modified Live Virus Vaccine (USDA: 1351.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002097">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002415"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000901"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002097</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1682</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1683</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1684</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1682</obo:VO_0001818>
        <obo:VO_0001818>1683</obo:VO_0001818>
        <obo:VO_0001818>1684</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1381.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Hepatitis-Parainfluenza Modified Live Virus Vaccine (USDA: 1381.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002098 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002098">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002394"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002098</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1576</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1577</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1576</obo:VO_0001818>
        <obo:VO_0001818>1577</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13A1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine (USDA: 13A1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002099 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002099</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1578</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1579</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1578</obo:VO_0001818>
        <obo:VO_0001818>1579</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13A1.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine (USDA: 13A1.27)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002100 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002100</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1609</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1610</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1611</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1609</obo:VO_0001818>
        <obo:VO_0001818>1610</obo:VO_0001818>
        <obo:VO_0001818>1611</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13C1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza Modified Live Virus Vaccine (USDA: 13C1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002101">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002101</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1612</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1613</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1614</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1615</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1612</obo:VO_0001818>
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        <obo:VO_0001818>1614</obo:VO_0001818>
        <obo:VO_0001818>1615</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002102 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002102</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1616</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1617</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1618</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1619</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1616</obo:VO_0001818>
        <obo:VO_0001818>1617</obo:VO_0001818>
        <obo:VO_0001818>1618</obo:VO_0001818>
        <obo:VO_0001818>1619</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002103">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002103</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1620</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1621</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1622</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1623</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1620</obo:VO_0001818>
        <obo:VO_0001818>1621</obo:VO_0001818>
        <obo:VO_0001818>1622</obo:VO_0001818>
        <obo:VO_0001818>1623</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002104">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002408"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002104</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1624</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1625</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1626</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1627</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1624</obo:VO_0001818>
        <obo:VO_0001818>1625</obo:VO_0001818>
        <obo:VO_0001818>1626</obo:VO_0001818>
        <obo:VO_0001818>1627</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002105 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002105">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002408"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002105</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1628</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1629</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1630</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1631</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1628</obo:VO_0001818>
        <obo:VO_0001818>1629</obo:VO_0001818>
        <obo:VO_0001818>1630</obo:VO_0001818>
        <obo:VO_0001818>1631</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002106 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002106">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002408"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002106</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1632</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1633</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1634</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1635</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1632</obo:VO_0001818>
        <obo:VO_0001818>1633</obo:VO_0001818>
        <obo:VO_0001818>1634</obo:VO_0001818>
        <obo:VO_0001818>1635</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.27)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002107 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002107">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002408"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002107</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1636</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1637</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1638</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1639</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1636</obo:VO_0001818>
        <obo:VO_0001818>1637</obo:VO_0001818>
        <obo:VO_0001818>1638</obo:VO_0001818>
        <obo:VO_0001818>1639</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.28</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.28)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002108 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002108">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002108</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1640</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1641</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1642</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1643</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1640</obo:VO_0001818>
        <obo:VO_0001818>1641</obo:VO_0001818>
        <obo:VO_0001818>1642</obo:VO_0001818>
        <obo:VO_0001818>1643</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.29</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.29)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002109 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002109</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1644</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1645</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1646</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1647</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1644</obo:VO_0001818>
        <obo:VO_0001818>1645</obo:VO_0001818>
        <obo:VO_0001818>1646</obo:VO_0001818>
        <obo:VO_0001818>1647</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Canarypox Vector Vaccine (USDA: 13D1.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002110 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002110</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1648</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1649</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1650</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1651</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1648</obo:VO_0001818>
        <obo:VO_0001818>1649</obo:VO_0001818>
        <obo:VO_0001818>1650</obo:VO_0001818>
        <obo:VO_0001818>1651</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13D1.T0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.T0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002111 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002111</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1652</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1653</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1654</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1655</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1656</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1652</obo:VO_0001818>
        <obo:VO_0001818>1653</obo:VO_0001818>
        <obo:VO_0001818>1654</obo:VO_0001818>
        <obo:VO_0001818>1655</obo:VO_0001818>
        <obo:VO_0001818>1656</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13G9.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus-Rabies Modified Live &amp; Killed Virus Vaccine (USDA: 13G9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002112 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002112</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1672</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1673</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1674</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1675</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1672</obo:VO_0001818>
        <obo:VO_0001818>1673</obo:VO_0001818>
        <obo:VO_0001818>1674</obo:VO_0001818>
        <obo:VO_0001818>1675</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13H9.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parvovirus-Rabies Modified Live &amp; Killed Virus Vaccine (USDA: 13H9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002113 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002113</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1687</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1688</obo:IAO_0000119>
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        <obo:VO_0001818>1687</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 13P1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002114 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002114</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1689</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1690</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1689</obo:VO_0001818>
        <obo:VO_0001818>1690</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13P1.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.27)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002115 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002115</metadata:prefixIRI>
        <obo:IAO_0000115>A horse Encephalomyelitis-Influenza-West Nile Virus vaccine that is inactivated and manufactured by Wyeth Pharmaceuticals Inc. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1717</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1718</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1719</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1720</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>1717</obo:VO_0001818>
        <obo:VO_0001818>1718</obo:VO_0001818>
        <obo:VO_0001818>1719</obo:VO_0001818>
        <obo:VO_0001818>1720</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 13W5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-Influenza-West Nile Virus Eastern &amp; Western, Killed Virus Vaccine (USDA: 13W5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002116 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002424"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002116</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1715</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1716</obo:IAO_0000119>
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        <obo:VO_0001818>1715</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1475.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis Eastern &amp; Western, Killed Virus Vaccine (USDA: 1475.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002117 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002117</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1676</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1677</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1678</obo:IAO_0000119>
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        <obo:VO_0001818>1676</obo:VO_0001818>
        <obo:VO_0001818>1677</obo:VO_0001818>
        <obo:VO_0001818>1678</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14D7.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Coronavirus-Parvovirus Modified Live &amp; Killed Virus Vaccine (USDA: 14D7.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002118 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002118</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1679</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1680</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        <obo:VO_0001818>1679</obo:VO_0001818>
        <obo:VO_0001818>1680</obo:VO_0001818>
        <obo:VO_0001818>1681</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14D9.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Coronavirus-Parvovirus Modified Live &amp; Killed Virus Vaccine (USDA: 14D9.27)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002119</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 14M1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Parainfluenza-Bordetella Bronchiseptica Modified Live Virus, Avirulent Live Culture Vaccine (USDA: 14M1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002120 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002120</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1695</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1696</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1695</obo:VO_0001818>
        <obo:VO_0001818>1696</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14M1.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Parainfluenza-Bordetella Bronchiseptica Modified Live Virus, Avirulent Live Culture Vaccine (USDA: 14M1.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002121 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002393"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002121</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1564</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1565</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1564</obo:VO_0001818>
        <obo:VO_0001818>1565</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14R1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus-Parvovirus Modified Live Virus Vaccine (USDA: 14R1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002122 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002122</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1566</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1567</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1566</obo:VO_0001818>
        <obo:VO_0001818>1567</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14R7.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus-Parvovirus Modified Live &amp; Killed Virus Vaccine (USDA: 14R7.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002123 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002123">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002123</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1568</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1569</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1568</obo:VO_0001818>
        <obo:VO_0001818>1569</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14R7.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus-Parvovirus Modified Live &amp; Killed Virus Vaccine (USDA: 14R7.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002124 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002124">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002124</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1570</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1571</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1570</obo:VO_0001818>
        <obo:VO_0001818>1571</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14R7.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus-Parvovirus Modified Live &amp; Killed Virus Vaccine (USDA: 14R7.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002125 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002125">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002125</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1572</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1573</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1572</obo:VO_0001818>
        <obo:VO_0001818>1573</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14R7.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus-Parvovirus Modified Live &amp; Killed Virus Vaccine (USDA: 14R7.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002126 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002126</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1574</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 14R7.29</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus-Parvovirus Modified Live &amp; Killed Virus Vaccine (USDA: 14R7.29)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002127 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002127</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1721</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1722</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1723</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>1721</obo:VO_0001818>
        <obo:VO_0001818>1722</obo:VO_0001818>
        <obo:VO_0001818>1723</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14W5.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-West Nile Virus Eastern &amp; Western, Killed Virus Vaccine (USDA: 14W5.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002128 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002128</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1724</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1725</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1726</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1727</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>1724</obo:VO_0001818>
        <obo:VO_0001818>1725</obo:VO_0001818>
        <obo:VO_0001818>1726</obo:VO_0001818>
        <obo:VO_0001818>1727</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14W5.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-West Nile Virus Eastern &amp; Western &amp; Venezuelan, Killed Virus Vaccine (USDA: 14W5.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002129 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002129</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1728</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1729</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1728</obo:VO_0001818>
        <obo:VO_0001818>1729</obo:VO_0001818>
        <obo:VO_0001818>1730</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 14W7.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-West Nile Virus Eastern &amp; Western, Killed Virus, Live Canarypox Vector Vaccine (USDA: 14W7.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002130 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002130</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1746</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1747</obo:IAO_0000119>
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        <obo:VO_0001818>1746</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1515.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002131 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002131</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1748</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1515.26</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.26)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002132 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.27)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002133 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1752</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1753</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>1752</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1515.2A</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.2A)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002134 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1754</obo:VO_0001818>
        <obo:VO_0001818>1755</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1518.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Equine Rhinopneumonitis-Influenza Modified Live &amp; Killed Virus Vaccine (USDA: 1518.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002135 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>1580</obo:VO_0001818>
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    <!-- http://purl.obolibrary.org/obo/VO_0002136 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002137 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine (USDA: 1599.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002138 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 1599.25</oboInOwl:hasDbXref>
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    <!-- http://purl.obolibrary.org/obo/VO_0002139 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000701"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002139</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1600</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1601</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1602</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1603</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1604</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>1600</obo:VO_0001818>
        <obo:VO_0001818>1601</obo:VO_0001818>
        <obo:VO_0001818>1602</obo:VO_0001818>
        <obo:VO_0001818>1603</obo:VO_0001818>
        <obo:VO_0001818>1604</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1599.29</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine (USDA: 1599.29)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002140 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002444"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002140</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1921</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1922</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1921</obo:VO_0001818>
        <obo:VO_0001818>1922</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 15E2.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Pox-Marek&apos;s Disease Serotype 3, Live Virus Vaccine (USDA: 15E2.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002141 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002441"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002141</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1909</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1910</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1909</obo:VO_0001818>
        <obo:VO_0001818>1910</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16J1.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Laryngotracheitis-Marek&apos;s Disease Serotype 3, Live Marek&apos;s Disease Vector Vaccine (USDA: 16J1.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002142 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002142">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002441"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002142</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1911</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1912</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1911</obo:VO_0001818>
        <obo:VO_0001818>1912</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16J1.R2</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Laryngotracheitis-Marek&apos;s Disease Serotypes 2 &amp; 3, Modified Live &amp; Live Marek&apos;s Disease Vector Vaccine (USDA: 16J1.R2)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002143 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002143">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002447"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002143</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1953</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1954</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1953</obo:VO_0001818>
        <obo:VO_0001818>1954</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16N1.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease-Newcastle Disease Serotype 3, Live Marek&apos;s Disease Vector Vaccine (USDA: 16N1.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002144 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002144">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002447"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001001"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002144</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1955</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1956</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1955</obo:VO_0001818>
        <obo:VO_0001818>1956</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16N1.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease-Newcastle Disease Serotypes 1 &amp; 3, Live Virus, Live Marek&apos;s Disease Vector Vaccine (USDA: 16N1.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002145 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002447"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002145</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1957</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1958</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1957</obo:VO_0001818>
        <obo:VO_0001818>1958</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16N1.R2</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease-Newcastle Disease Serotypes 1 &amp; 2 &amp; 3, Live Virus, Live Marek&apos;s Disease Vector Vaccine (USDA: 16N1.R2)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001019"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002448"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002146</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1963</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1964</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1963</obo:VO_0001818>
        <obo:VO_0001818>1964</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16T1.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease-Tenosynovitis Serotypes 2 &amp; 3, Live &amp; Modified Live Virus Vaccine (USDA: 16T1.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002147 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002147">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001019"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002448"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002147</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1965</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1966</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1965</obo:VO_0001818>
        <obo:VO_0001818>1966</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 16T1.03</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease-Tenosynovitis Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 16T1.03)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002148 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002148">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002148</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1996</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1997</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1996</obo:VO_0001818>
        <obo:VO_0001818>1997</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1761.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002149 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002149">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002149</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1998</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1999</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1998</obo:VO_0001818>
        <obo:VO_0001818>1999</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1761.12</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.12)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002150</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2000</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2001</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2000</obo:VO_0001818>
        <obo:VO_0001818>2001</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1761.13</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Conn Type, Live Virus Vaccine (USDA: 1761.13)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002151 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002151">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002151</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2002</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2003</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2002</obo:VO_0001818>
        <obo:VO_0001818>2003</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1761.14</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1761.14)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002152 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002152">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002152</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2004</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2005</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2004</obo:VO_0001818>
        <obo:VO_0001818>2005</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1761.15</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1761.15)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002153 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002153">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002153</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2006</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2007</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2006</obo:VO_0001818>
        <obo:VO_0001818>2007</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1761.17</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1761.17)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002154 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002154">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002154</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2008</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2009</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2008</obo:VO_0001818>
        <obo:VO_0001818>2009</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1761.18</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.18)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002155 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002155">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002155</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2010</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2011</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2010</obo:VO_0001818>
        <obo:VO_0001818>2011</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1761.19</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.19)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002156 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002156">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002156</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2012</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2013</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2012</obo:VO_0001818>
        <obo:VO_0001818>2013</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1761.1A</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Conn Type, Live Virus Vaccine (USDA: 1761.1A)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002157 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002157">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002157</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2014</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2015</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2014</obo:VO_0001818>
        <obo:VO_0001818>2015</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1762.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1762.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002158 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002158">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002158</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2016</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2017</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2016</obo:VO_0001818>
        <obo:VO_0001818>2017</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1762.13</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Conn Type, Live Virus Vaccine (USDA: 1762.13)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002159 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002159">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002159</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2018</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2019</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2018</obo:VO_0001818>
        <obo:VO_0001818>2019</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1762.1H</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1762.1H)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002160 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002160">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002160</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2020</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2021</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2020</obo:VO_0001818>
        <obo:VO_0001818>2021</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1771.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002161 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002161">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002161</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2022</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2023</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2022</obo:VO_0001818>
        <obo:VO_0001818>2023</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1771.12</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.12)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002162">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002162</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2024</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2025</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2024</obo:VO_0001818>
        <obo:VO_0001818>2025</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1771.14</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, LaSota Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1771.14)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002163 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002163">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002163</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2026</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2027</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2026</obo:VO_0001818>
        <obo:VO_0001818>2027</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1771.17</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, LaSota Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1771.17)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002164 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002164">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002164</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2028</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2029</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2028</obo:VO_0001818>
        <obo:VO_0001818>2029</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1771.18</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.18)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002165 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002165">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002165</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2030</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2031</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2030</obo:VO_0001818>
        <obo:VO_0001818>2031</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1771.19</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.19)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002166 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002166">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002166</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2032</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2033</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2032</obo:VO_0001818>
        <obo:VO_0001818>2033</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1771.1A</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.1A)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002167 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002167</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2034</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2035</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2034</obo:VO_0001818>
        <obo:VO_0001818>2035</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1775.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1775.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002168 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002168</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2036</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2037</obo:IAO_0000119>
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        <obo:VO_0001818>2036</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1775.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1775.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002169 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002169</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2038</obo:IAO_0000119>
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        <obo:VO_0001818>2038</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1776.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1776.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002170 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002170</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2040</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1785.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis Mass &amp; Ark Types, Killed Virus Vaccine (USDA: 1785.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002171 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002171</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2042</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 1785.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1785.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002172 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Newcastle-Bronchitis Mass &amp; Ark Types, Killed Virus Vaccine (USDA: 1785.12)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002173 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002173</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2046</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2047</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2046</obo:VO_0001818>
        <obo:VO_0001818>2047</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1791.14</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1791.14)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002174 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002174</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2048</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2049</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2048</obo:VO_0001818>
        <obo:VO_0001818>2049</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1791.15</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1791.15)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002175 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002175</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2050</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2051</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2050</obo:VO_0001818>
        <obo:VO_0001818>2051</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1791.19</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1791.19)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002176 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002176</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2052</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2053</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2054</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2055</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2052</obo:VO_0001818>
        <obo:VO_0001818>2053</obo:VO_0001818>
        <obo:VO_0001818>2054</obo:VO_0001818>
        <obo:VO_0001818>2055</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1791.1X</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Ark Types, Live Virus Vaccine (USDA: 1791.1X)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002177 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002177</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2056</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2057</obo:IAO_0000119>
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        <obo:VO_0001818>2056</obo:VO_0001818>
        <obo:VO_0001818>2057</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 17A1.1M</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Ark Types, Live Virus Vaccine (USDA: 17A1.1M)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002178 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002178</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2058</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2059</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2058</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 17A1.1N</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Ark Types, Live Virus Vaccine (USDA: 17A1.1N)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002179 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002179</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2060</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2061</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2060</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 17A2.1M</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, B1 Strain, Mass &amp; Ark Types, Live Virus Vaccine (USDA: 17A2.1M)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002180 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002180</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2062</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2063</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2062</obo:VO_0001818>
        <obo:VO_0001818>2063</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 17B1.17</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, LaSota Strain, Mass &amp; Conn Types Vaccine (USDA: 17B1.17)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002456"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002181</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1994</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1995</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1994</obo:VO_0001818>
        <obo:VO_0001818>1995</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 17C1.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease-Fowl Pox Live Fowl Pox Vector Vaccine (USDA: 17C1.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002447"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002182</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1959</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1960</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1959</obo:VO_0001818>
        <obo:VO_0001818>1960</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 17H1.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease-Newcastle Disease Serotypes 2 &amp; 3, Live Virus &amp; Live Marek&apos;s Disease Vector Vaccine (USDA: 17H1.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002183 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002183">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002447"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002183</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1961</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1962</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1961</obo:VO_0001818>
        <obo:VO_0001818>1962</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 17H1.R2</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease-Newcastle Disease Serotypes 2 &amp; 3, Live Virus &amp; Live Marek&apos;s Disease Vector Vaccine (USDA: 17H1.R2)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002184">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002458"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002184</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2072</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2073</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2072</obo:VO_0001818>
        <obo:VO_0001818>2073</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 17P5.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 17P5.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002185">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002185</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2064</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2065</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2064</obo:VO_0001818>
        <obo:VO_0001818>2065</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 17V1.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis VG/GA Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 17V1.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002186 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002186">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002186</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2066</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2067</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2066</obo:VO_0001818>
        <obo:VO_0001818>2067</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 17V1.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis VG/GA Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 17V1.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002187 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002187">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002187</metadata:prefixIRI>
        <obo:IAO_0000116>generated using OntoRat</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001826"/>
        <rdfs:label>obsolete Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine (USDA: 19A5.12)</rdfs:label>
        <rdfs:seeAlso>USDA: 19A5.12</rdfs:seeAlso>
        <rdfs:seeAlso>violinID:2128</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002188 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002188">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002188</metadata:prefixIRI>
        <obo:IAO_0000116>generated using OntoRat</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001827"/>
        <rdfs:label>obsolete Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine (USDA: 19A5.22)</rdfs:label>
        <rdfs:seeAlso>USDA: 19A5.22</rdfs:seeAlso>
        <rdfs:seeAlso>violinID:2129</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002189 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002189">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002189</metadata:prefixIRI>
        <obo:IAO_0000116>generated using OntoRat</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001828"/>
        <rdfs:label>obsolete Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine (USDA: 19A5.23)</rdfs:label>
        <rdfs:seeAlso>USDA: 19A5.23</rdfs:seeAlso>
        <rdfs:seeAlso>violinID:2130</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002190 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002190">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002190</metadata:prefixIRI>
        <obo:IAO_0000116>generated using OntoRat</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001829"/>
        <rdfs:label>obsolete Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine (USDA: 19A5.24)</rdfs:label>
        <rdfs:seeAlso>USDA: 19A5.24</rdfs:seeAlso>
        <rdfs:seeAlso>violinID:2131</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002191 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002191">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002191</metadata:prefixIRI>
        <obo:IAO_0000116>generated using OntoRat</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001830"/>
        <rdfs:label>obsolete Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine (USDA: 19A5.26)</rdfs:label>
        <rdfs:seeAlso>USDA: 19A5.26</rdfs:seeAlso>
        <rdfs:seeAlso>violinID:2132</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002192">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002192</metadata:prefixIRI>
        <obo:IAO_0000116>generated using OntoRat</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001831"/>
        <rdfs:label>obsolete Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine (USDA: 19A5.29)</rdfs:label>
        <rdfs:seeAlso>USDA: 19A5.29</rdfs:seeAlso>
        <rdfs:seeAlso>violinID:2133</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002193 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002193">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002475"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002193</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2105</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2106</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2105</obo:VO_0001818>
        <obo:VO_0001818>2106</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 19H1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine (USDA: 19H1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002194">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002194</metadata:prefixIRI>
        <obo:IAO_0000116>generated using OntoRat</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001825"/>
        <rdfs:label>obsolete Porcine Circovirus Type 2, Killed Baculovirus Vector Vaccine (USDA: 19K5.R0)</rdfs:label>
        <rdfs:seeAlso>USDA: 19K5.R0</rdfs:seeAlso>
        <rdfs:seeAlso>violinID:2096</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002195 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002195">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001524"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000701"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002195</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2097</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2097</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
        <oboInOwl:hasDbXref>USDA: 19K5.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Circovirus Type 1 - Type 2 Chimera, Killed Virus Vaccine (USDA: 19K5.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002196 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002196">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002382"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000701"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002196</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1447</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1448</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1447</obo:VO_0001818>
        <obo:VO_0001818>1448</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1A82.50</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotype 3, Live Virus Vaccine (USDA: 1A82.50)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002197 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002197">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002382"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002197</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1449</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1450</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1449</obo:VO_0001818>
        <obo:VO_0001818>1450</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1A88.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotype 3, Live Marek&apos;s Disease Vector Vaccine (USDA: 1A88.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002198 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002198">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002382"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002198</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1451</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1452</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1451</obo:VO_0001818>
        <obo:VO_0001818>1452</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1A88.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus, Live Marek&apos;s Disease Vector Vaccine (USDA: 1A88.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002199 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002199">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002382"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002199</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1453</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1454</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1453</obo:VO_0001818>
        <obo:VO_0001818>1454</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1A88.R2</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus, Live Marek&apos;s Disease Vector Vaccine (USDA: 1A88.R2)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002200 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002200">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002382"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000701"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002200</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1455</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1456</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1455</obo:VO_0001818>
        <obo:VO_0001818>1456</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1B82.50</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Marek&apos;s Disease Serotypes 2 &amp; 3, Live Virus Vaccine (USDA: 1B82.50)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002201 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002201">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002445"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001001"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002201</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1923</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1924</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>1923</obo:VO_0001818>
        <obo:VO_0001818>1924</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1D51.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Pox-Mycoplasma Gallisepticum Live Fowl Pox Vector Vaccine (USDA: 1D51.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002202 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002202">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002443"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002202</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1919</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1920</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>1919</obo:VO_0001818>
        <obo:VO_0001818>1920</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1F31.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Pox-Laryngotracheitis Live Fowl Pox Vector Vaccine (USDA: 1F31.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002203 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002203">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002203</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2068</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2069</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2068</obo:VO_0001818>
        <obo:VO_0001818>2069</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1XB1.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, C2 Strain, Mass Type, Live Virus Vaccine (USDA: 1XB1.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002204 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002204">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001018"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002204</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2070</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2071</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2070</obo:VO_0001818>
        <obo:VO_0001818>2071</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 1XC1.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis B1 Type, C2 Strain, Mass &amp; Conn Types, Live Virus Vaccine (USDA: 1XC1.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002205 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002205">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002489"/>
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            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002205</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2150</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2151</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2150</obo:VO_0001818>
        <obo:VO_0001818>2151</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:hasDbXref>USDA: 40A5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 40A5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002206 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002206</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2574</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2575</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2576</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2574</obo:VO_0001818>
        <obo:VO_0001818>2575</obo:VO_0001818>
        <obo:VO_0001818>2576</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4629.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4629.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002207 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002207</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2571</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2572</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2571</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4629.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4629.27)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002208 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002208</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2696</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4637.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002209 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002209</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2701</obo:VO_0001818>
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        <obo:VO_0001818>2705</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4637.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002210 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002210</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 4637.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002211 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002211</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2671</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2672</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2673</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2674</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2675</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2671</obo:VO_0001818>
        <obo:VO_0001818>2672</obo:VO_0001818>
        <obo:VO_0001818>2673</obo:VO_0001818>
        <obo:VO_0001818>2674</obo:VO_0001818>
        <obo:VO_0001818>2675</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4637.29</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4637.29)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002212 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002212">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002412"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002212</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2711</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2712</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2713</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2714</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2715</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2711</obo:VO_0001818>
        <obo:VO_0001818>2712</obo:VO_0001818>
        <obo:VO_0001818>2713</obo:VO_0001818>
        <obo:VO_0001818>2714</obo:VO_0001818>
        <obo:VO_0001818>2715</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4639.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002213 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002213">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002412"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002213</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2716</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2717</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2718</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2719</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2720</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2716</obo:VO_0001818>
        <obo:VO_0001818>2717</obo:VO_0001818>
        <obo:VO_0001818>2718</obo:VO_0001818>
        <obo:VO_0001818>2719</obo:VO_0001818>
        <obo:VO_0001818>2720</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4639.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002214 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002214">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002409"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002214</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2676</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2677</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2678</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2679</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2680</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2676</obo:VO_0001818>
        <obo:VO_0001818>2677</obo:VO_0001818>
        <obo:VO_0001818>2678</obo:VO_0001818>
        <obo:VO_0001818>2679</obo:VO_0001818>
        <obo:VO_0001818>2680</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4639.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4639.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002215 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002215">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002215</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2686</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2687</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2688</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2689</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2690</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2686</obo:VO_0001818>
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        <obo:VO_0001818>2688</obo:VO_0001818>
        <obo:VO_0001818>2689</obo:VO_0001818>
        <obo:VO_0001818>2690</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4639.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.27)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002216 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002216">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002216</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2691</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2692</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2694</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2695</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2691</obo:VO_0001818>
        <obo:VO_0001818>2692</obo:VO_0001818>
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        <obo:VO_0001818>2694</obo:VO_0001818>
        <obo:VO_0001818>2695</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4639.28</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.28)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002217 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002217">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002404"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001119"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002217</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2721</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2722</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2723</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2724</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2725</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2721</obo:VO_0001818>
        <obo:VO_0001818>2722</obo:VO_0001818>
        <obo:VO_0001818>2723</obo:VO_0001818>
        <obo:VO_0001818>2724</obo:VO_0001818>
        <obo:VO_0001818>2725</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4639.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Live Canarypox Vector Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002218 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002218">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002218</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2667</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2668</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2669</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2670</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2667</obo:VO_0001818>
        <obo:VO_0001818>2668</obo:VO_0001818>
        <obo:VO_0001818>2669</obo:VO_0001818>
        <obo:VO_0001818>2670</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4659.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4659.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002219 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002219">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002399"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000701"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002219</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2589</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2590</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2591</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2592</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2593</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2594</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2595</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2589</obo:VO_0001818>
        <obo:VO_0001818>2590</obo:VO_0001818>
        <obo:VO_0001818>2591</obo:VO_0001818>
        <obo:VO_0001818>2592</obo:VO_0001818>
        <obo:VO_0001818>2593</obo:VO_0001818>
        <obo:VO_0001818>2594</obo:VO_0001818>
        <obo:VO_0001818>2595</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46B9.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46B9.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002220 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002220">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002220</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2569</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2570</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2569</obo:VO_0001818>
        <obo:VO_0001818>2570</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46D5.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46D5.27)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002221 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002221">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002390"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002221</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2567</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2568</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2567</obo:VO_0001818>
        <obo:VO_0001818>2568</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46E5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46E5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002222 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002222">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002389"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002222</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2559</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2560</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2559</obo:VO_0001818>
        <obo:VO_0001818>2560</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46E5.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46E5.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002223 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002223">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002390"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002223</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2563</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2564</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2563</obo:VO_0001818>
        <obo:VO_0001818>2564</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46E5.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46E5.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002224">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002389"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002224</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2561</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2562</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2561</obo:VO_0001818>
        <obo:VO_0001818>2562</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46E5.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46E5.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002225 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002225">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002390"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0001027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002225</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2565</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2566</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2565</obo:VO_0001818>
        <obo:VO_0001818>2566</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46E5.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46E5.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002226 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002226">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002403"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002226</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2632</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2633</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2634</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2635</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2636</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2637</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2632</obo:VO_0001818>
        <obo:VO_0001818>2633</obo:VO_0001818>
        <obo:VO_0001818>2634</obo:VO_0001818>
        <obo:VO_0001818>2635</obo:VO_0001818>
        <obo:VO_0001818>2636</obo:VO_0001818>
        <obo:VO_0001818>2637</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46J7.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002227 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002227">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000841"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002227</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2638</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2639</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2640</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2641</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2642</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2643</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2638</obo:VO_0001818>
        <obo:VO_0001818>2639</obo:VO_0001818>
        <obo:VO_0001818>2640</obo:VO_0001818>
        <obo:VO_0001818>2641</obo:VO_0001818>
        <obo:VO_0001818>2642</obo:VO_0001818>
        <obo:VO_0001818>2643</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46J7.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002228 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002228">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002412"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002228</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2726</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2727</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2726</obo:VO_0001818>
        <obo:VO_0001818>2727</obo:VO_0001818>
        <obo:VO_0001818>2728</obo:VO_0001818>
        <obo:VO_0001818>2729</obo:VO_0001818>
        <obo:VO_0001818>2730</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46J8.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J8.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002229 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002229</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2644</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2645</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2648</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2649</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2644</obo:VO_0001818>
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        <obo:VO_0001818>2648</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 46J9.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002230 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002230</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2618</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2619</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2614</obo:VO_0001818>
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        <obo:VO_0001818>2617</obo:VO_0001818>
        <obo:VO_0001818>2618</obo:VO_0001818>
        <obo:VO_0001818>2619</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 46J9.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002231 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002231</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2596</obo:VO_0001818>
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        <obo:VO_0001818>2599</obo:VO_0001818>
        <obo:VO_0001818>2600</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 46J9.25</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.25)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002232 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002232</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2620</obo:VO_0001818>
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        <obo:VO_0001818>2624</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 46J9.26</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002233 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002233</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2626</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2631</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2626</obo:VO_0001818>
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        <obo:VO_0001818>2630</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 46J9.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.27)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002234 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002234</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2606</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2607</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2602</obo:VO_0001818>
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        <obo:VO_0001818>2606</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 46J9.29</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.29)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002235 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002235</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 46J9.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002236 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002236</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 46L9.27</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002237 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002237</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 46P9.27</oboInOwl:hasDbXref>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002238 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2799</obo:IAO_0000119>
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        <obo:VO_0001818>2799</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-Influenza-West Nile Virus Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 46W5.21)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002239 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Canine Coronavirus Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47A5.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002240 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002241 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002242 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002243 -->

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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2553</obo:VO_0001818>
        <obo:VO_0001818>2554</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 47E5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002244 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002244</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2556</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2557</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2556</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 47E5.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002245 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002245</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2681</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2682</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2684</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2685</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2681</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 47K1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47K1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002246 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002246</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2612</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2613</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2608</obo:VO_0001818>
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        <obo:VO_0001818>2611</obo:VO_0001818>
        <obo:VO_0001818>2612</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 47L9.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live &amp; Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47L9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002247 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002247</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2731</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2732</obo:IAO_0000119>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2734</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2735</obo:IAO_0000119>
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        <obo:VO_0001818>2731</obo:VO_0001818>
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        <obo:VO_0001818>2734</obo:VO_0001818>
        <obo:VO_0001818>2735</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 47P9.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Hepatitis-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 47P9.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002248 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002248</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2768</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2769</obo:IAO_0000119>
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        <obo:VO_0001818>2768</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4835.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-Influenza Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002249 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2771</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2772</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>2771</obo:VO_0001818>
        <obo:VO_0001818>2772</obo:VO_0001818>
        <obo:VO_0001818>2773</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4835.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-Influenza Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.23)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002250 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2774</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2775</obo:IAO_0000119>
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        <obo:VO_0001818>2774</obo:VO_0001818>
        <obo:VO_0001818>2775</obo:VO_0001818>
        <obo:VO_0001818>2776</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4835.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-Influenza Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.24)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002251 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2777</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2778</obo:IAO_0000119>
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        <obo:VO_0001818>2777</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4835.45</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-Influenza Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.45)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002252 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Encephalomyelitis-Influenza Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.46)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002253 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002253</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 4844.30</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-Rhinopneumonitis Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4844.30)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002254 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002254</metadata:prefixIRI>
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    <!-- http://purl.obolibrary.org/obo/VO_0002255 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002256 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002257 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002258 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002259 -->

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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>2850</obo:VO_0001818>
        <obo:VO_0001818>2851</obo:VO_0001818>
        <obo:VO_0001818>2852</obo:VO_0001818>
        <obo:VO_0001818>2853</obo:VO_0001818>
        <obo:VO_0001818>2854</obo:VO_0001818>
        <obo:VO_0001818>2855</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4855.R2</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-Rhinopneumonitis-Influenza-West Nile Virus Eastern &amp; Western, Killed Virus, Killed Flavivirus Chimera Vaccine-Tetanus Toxoid (USDA: 4855.R2)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002263 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002263</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2740</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2741</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2742</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>2740</obo:VO_0001818>
        <obo:VO_0001818>2741</obo:VO_0001818>
        <obo:VO_0001818>2742</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4865.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002264 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002264</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2743</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2744</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2745</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>2743</obo:VO_0001818>
        <obo:VO_0001818>2744</obo:VO_0001818>
        <obo:VO_0001818>2745</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4865.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002265 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002265</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2746</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2747</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2748</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2746</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4865.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002266 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002266</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2749</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2750</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 4865.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis Eastern &amp; Western &amp; Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002267 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002268 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002269 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002270 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002271 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002272 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002273 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002274 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002275 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis Mass Type, Killed Virus Vaccine-Mycoplasma Gallisepticum Bacterin (USDA: 48B5.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002276 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002276</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2914</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2915</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2916</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>2914</obo:VO_0001818>
        <obo:VO_0001818>2915</obo:VO_0001818>
        <obo:VO_0001818>2916</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 48B6.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis Mass Type, Killed Virus Vaccine-Mycoplasma Gallisepticum Bacterin (USDA: 48B6.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002277 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002277">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002277</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2933</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2934</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2935</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2933</obo:VO_0001818>
        <obo:VO_0001818>2934</obo:VO_0001818>
        <obo:VO_0001818>2935</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 48C5.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002278">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002278</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2936</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2937</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2938</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2936</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 48C5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002279 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002279</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2939</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2940</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 48C5.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002280 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002280</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2942</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2943</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 48C5.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002281">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002281</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 48D6.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis Mass Type, Killed Virus Vaccine-Salmonella Enteritidis Bacterin (USDA: 48D6.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002282 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2905</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2906</obo:IAO_0000119>
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        <obo:VO_0001818>2905</obo:VO_0001818>
        <obo:VO_0001818>2906</obo:VO_0001818>
        <obo:VO_0001818>2907</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 48D7.10</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease-Bronchitis Mass &amp; Ark Types, Killed Virus Vaccine-Salmonella Enteritidis Bacterin (USDA: 48D7.10)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002283 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2908</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2909</obo:IAO_0000119>
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        <obo:VO_0001818>2908</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 48D7.11</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease-Bronchitis Mass &amp; Ark Types, Killed Virus Vaccine-Salmonella Enteritidis Bacterin (USDA: 48D7.11)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002284 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2860</obo:IAO_0000119>
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        <obo:VO_0001818>2856</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-West Nile Virus Eastern &amp; Western &amp; Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002285 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Encephalomyelitis-West Nile Virus Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.21)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002286 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>2865</obo:VO_0001818>
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        <rdfs:label>Encephalomyelitis-West Nile Virus Eastern &amp; Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.22)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002287 -->

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        <obo:VO_0001818>2869</obo:VO_0001818>
        <obo:VO_0001818>2870</obo:VO_0001818>
        <obo:VO_0001818>2871</obo:VO_0001818>
        <obo:VO_0001818>2872</obo:VO_0001818>
        <obo:VO_0001818>2873</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 48W5.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-West Nile Virus Eastern &amp; Western &amp; Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002288 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002431"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002288</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2874</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2875</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2876</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2877</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0001818>2874</obo:VO_0001818>
        <obo:VO_0001818>2875</obo:VO_0001818>
        <obo:VO_0001818>2876</obo:VO_0001818>
        <obo:VO_0001818>2877</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 48W9.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Encephalomyelitis-West Nile Virus Eastern &amp; Western, Killed Virus, Live Canarypox Vector Vaccine-Tetanus Toxoid (USDA: 48W9.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002289 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002289">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000409"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002476"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002289</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3010</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>3010</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4905.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies Killed Virus Vaccine-Ehrlichia Risticii Bacterin (USDA: 4905.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002290 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002290">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002290</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2922</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2923</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2922</obo:VO_0001818>
        <obo:VO_0001818>2923</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4906.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae Bacterin (USDA: 4906.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002291 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002291">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002291</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2951</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2952</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2951</obo:VO_0001818>
        <obo:VO_0001818>2952</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4960.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4960.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002292">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002292</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2945</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2946</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2945</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4975.01</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4975.01)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002293 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002293">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002293</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2947</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2948</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2947</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4975.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4975.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002294 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002294</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2949</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2950</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2949</obo:VO_0001818>
        <obo:VO_0001818>2950</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4975.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4975.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002295 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002295</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2920</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2921</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>2920</obo:VO_0001818>
        <obo:VO_0001818>2921</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:hasDbXref>USDA: 4989.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4989.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002296 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002296</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3035</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3036</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3037</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>USDA: 4990.00</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trichomonas Foetus Vaccine, Killed Protozoa-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4990.00)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002297 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002297</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3011</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3012</obo:IAO_0000119>
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        <obo:VO_0001818>3011</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4993.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae Bacterin (USDA: 4993.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002298 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002298</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3014</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 4993.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae Bacterin (USDA: 4993.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002299 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002299</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3015</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3016</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>3015</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4994.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.20)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002300 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3018</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3019</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>3018</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.21)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002301 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3021</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3022</obo:IAO_0000119>
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        <obo:VO_0001818>3021</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0002302 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002302</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3024</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3025</obo:IAO_0000119>
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        <obo:VO_0001818>3024</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4994.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.24)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002303 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002303</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>3027</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4995.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002304 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0001818>3029</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4995.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002305 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002306 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002307 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002307</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3003</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3004</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3005</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3006</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>3003</obo:VO_0001818>
        <obo:VO_0001818>3004</obo:VO_0001818>
        <obo:VO_0001818>3005</obo:VO_0001818>
        <obo:VO_0001818>3006</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49B1.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 49B1.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002308 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000619"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002471"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002308</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2991</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2992</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2993</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2991</obo:VO_0001818>
        <obo:VO_0001818>2992</obo:VO_0001818>
        <obo:VO_0001818>2993</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49C1.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus Modified Live Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 49C1.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002309 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002309</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2953</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2954</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2955</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2956</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2953</obo:VO_0001818>
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        <obo:VO_0001818>2955</obo:VO_0001818>
        <obo:VO_0001818>2956</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49F6.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus-Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49F6.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002310 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002310</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2957</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2958</obo:IAO_0000119>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2957</obo:VO_0001818>
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        <obo:VO_0001818>2959</obo:VO_0001818>
        <obo:VO_0001818>2960</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49F6.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus-Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49F6.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002311 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002311</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2961</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2962</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2963</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2964</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2961</obo:VO_0001818>
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        <obo:VO_0001818>2963</obo:VO_0001818>
        <obo:VO_0001818>2964</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49F6.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus-Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49F6.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002312 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002312</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2965</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2966</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2967</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2968</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2965</obo:VO_0001818>
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        <obo:VO_0001818>2967</obo:VO_0001818>
        <obo:VO_0001818>2968</obo:VO_0001818>
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        <rdfs:label>Parvovirus-Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49G6.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002313 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2969</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2970</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2971</obo:IAO_0000119>
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        <obo:VO_0001818>2969</obo:VO_0001818>
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        <obo:VO_0001818>2971</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 49G6.23</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus-Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49G6.23)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002314 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2973</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2974</obo:IAO_0000119>
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        <obo:VO_0001818>2973</obo:VO_0001818>
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        <obo:VO_0001818>2975</obo:VO_0001818>
        <obo:VO_0001818>2976</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49G6.24</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus-Swine Influenza H1N1 &amp; H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49G6.24)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002315 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002315</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2994</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2995</obo:IAO_0000119>
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        <obo:VO_0001818>2994</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 49K1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus Modified Live Virus Vaccine-Escherichia Coli Bacterin (USDA: 49K1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002316 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002316</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2977</obo:IAO_0000119>
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        <obo:VO_0001818>2977</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 49K5.R1</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Circovirus Type 2, Killed Baculovirus Vector Vaccine- Mycoplasma Hyopneumoniae Bacterin (USDA: 49K5.R1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002317 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002317</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>2984</obo:VO_0001818>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
        <oboInOwl:hasDbXref>USDA: 49K9.R0</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome-Circovirus Reproductive &amp; Respiratory Form, Type 2, Modifed Live Virus,Killed Baculovirus Vector Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 49K9.R0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002318 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3007</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3008</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3009</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>3007</obo:VO_0001818>
        <obo:VO_0001818>3008</obo:VO_0001818>
        <obo:VO_0001818>3009</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49P1.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine-Escherichia Coli Bacterin (USDA: 49P1.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002319 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002319</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2996</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2997</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2998</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2999</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3000</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3001</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3002</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2996</obo:VO_0001818>
        <obo:VO_0001818>2997</obo:VO_0001818>
        <obo:VO_0001818>2998</obo:VO_0001818>
        <obo:VO_0001818>2999</obo:VO_0001818>
        <obo:VO_0001818>3000</obo:VO_0001818>
        <obo:VO_0001818>3001</obo:VO_0001818>
        <obo:VO_0001818>3002</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 49T9.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine-Bordetella Bronchiseptica-Clostridium Perfringens Type C-Erysipelothrix Rhusiopathiae-Escherichia Coli-Pasteurella Multocida Bacterin-Toxoid (USDA: 49T9.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002320">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002320</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2878</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2879</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2880</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7898"/>
        <obo:VO_0001818>2878</obo:VO_0001818>
        <obo:VO_0001818>2879</obo:VO_0001818>
        <obo:VO_0001818>2880</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4A45.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Infectious Salmon Anemia Virus Killed Virus Vaccine-Aeromonas Salmonicida-Vibrio Anguillarum-Ordalii-Salmonicida Bacterin (USDA: 4A45.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002321 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002321</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2924</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2925</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2926</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2924</obo:VO_0001818>
        <obo:VO_0001818>2925</obo:VO_0001818>
        <obo:VO_0001818>2926</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4BC5.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4BC5.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002322 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002322">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002322</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2927</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2928</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2929</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2927</obo:VO_0001818>
        <obo:VO_0001818>2928</obo:VO_0001818>
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        <oboInOwl:hasDbXref>USDA: 4BC5.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4BC5.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002323 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002323</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2930</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>USDA: 4BC5.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4BC5.22)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002324 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000206"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002324</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2987</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2988</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2989</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2990</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2987</obo:VO_0001818>
        <obo:VO_0001818>2988</obo:VO_0001818>
        <obo:VO_0001818>2989</obo:VO_0001818>
        <obo:VO_0001818>2990</obo:VO_0001818>
        <oboInOwl:hasDbXref>USDA: 4P19.20</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome-Parvovirus Reproductive Form, Modified Live &amp; Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4P19.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002325 -->

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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002325</metadata:prefixIRI>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12618"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian encephalomyelitis-chicken anemia virus-fowl pox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002326 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002326">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000985"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001468"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001522"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002326</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian encephalomyelitis-fowl pox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002327 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002327">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002326"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002443"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002327</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian encephalomyelitis-fowl pox-laryngotracheitis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002328 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002328">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002326"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002445"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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            </owl:Restriction>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002328</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian encephalomyelitis-fowl pox-Mycoplasma gallisepticum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002329 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002329">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000461"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000985"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002329</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian influenza-fowl pox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002330 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002330">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000990"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002330</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Parainfluenza 3-Respiratory Syncytial Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002331 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002331">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000620"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002331</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bovine rhinotracheitis vaccine-haemophilus somnus-mannheimia haemolytica-pasteurella multocida bacterin-toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002332</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002333 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002333">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002334"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002333</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae- Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002334">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002335"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002334</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002335 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002335">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002336"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002335</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis Vaccine-Leptospira Hardjo-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002336 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002336">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_94063"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002336</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_94063"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bovine rhinotracheitis vaccine-leptospira pomona bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002337 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002337">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000620"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001523"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002338"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002337</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002338 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002338">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000987"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000990"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002338</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bovine rhinotracheitis-parainfluenza 3 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002339 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002339">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002338"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002339</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Haemophilus Somnus Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002340 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002340">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002338"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002340</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002341 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002341">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002342"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002341</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002342 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002342">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002336"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002338"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002342</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Leptospira Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002343 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002343">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002338"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002343</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002344 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002344">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002344</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Respiratory Syncytial Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002345 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002345">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001501"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002345</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002346 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002346">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000568"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002349"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002346</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Campylobacter Fetus-Leptospira CanicolaGrippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002347 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002347">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002337"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002347</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002348 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002348">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002347"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002348</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002349 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002349">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002350"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002349</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002350 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002350">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002351"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002350</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002351 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002351">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002352"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002351</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Hardjo-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002352 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002352">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001501"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002336"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002352</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002353 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002353">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002338"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002345"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002353</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002354 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002354">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000568"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002338"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002352"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002354</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002355 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002355">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002488"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002355</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002356 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002356">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000890"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002356</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002357 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002357">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001523"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002357</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Mannheimia Haemolytica Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002358 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002358">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002338"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002372"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002358</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002359">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000813"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002360"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000570"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002359</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Campylobacter Fetus-Haemophilus Somnus-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002360 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002360">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000568"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002360</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002361 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002361">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002361</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Haemophilus Somnus Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002362 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002362">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002361"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002362</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Haemophilus Somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002363 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002363">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002357"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002363</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Haemophilus Somnus-Mannheimia Haemolytica Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002364 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002364">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002368"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002364</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002365 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002365">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
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                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001497"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002365</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>chicken bursal disease-Newcastle disease vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002366 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002366">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001523"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002364"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002366</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona-Mannheimia Haemolytica Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002367 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002367">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001502"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002365"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002367</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002368 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002368">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002368</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Leptospira Hardjo Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002369 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002369">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001523"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002358"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002369</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Mannheimia Haemolytica Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002370 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002370">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002371"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002370</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002371 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002371">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000620"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002369"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002371</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus-Mannheimia Haemolytica-Pasteurella Multocida Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002372 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002372">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002345"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002372</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002373 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002373">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002372"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_94063"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002373</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_94063"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Vaccine-Leptospira Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002374 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002374">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10927"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000658"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001503"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002374</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11128"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002375 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002375">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000639"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000963"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002377"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002375</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_79668"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002376 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002376">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002375"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002376</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Vaccine-Clostridium Perfringens Types C &amp; D-Escherichia Coli Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002377 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002377">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002374"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002377</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rotavirus-Coronavirus Vaccine-Escherichia Coli Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002378 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002378">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000568"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002378</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002379 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002379">
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002379</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_75985"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002380 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002380">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002381"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002380</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002381 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002381">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001501"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002381</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_94063"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea Vaccine-Leptospira Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002382 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002382">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002382</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bursal disease-Mareks disease vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002383 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002383">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002367"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002383</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002384 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002384">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002365"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002384</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>chicken Bursal Disease-Newcastle Disease-Reovirus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002385">
        <owl:equivalentClass>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002385</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>chicken bursal disease-reovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002386">
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002387 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002387">
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-GrippotyphosaIcterohaemorrhagiae-Pomona Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002388 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002388">
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002389 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002389">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001468"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002390 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002390">
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002391 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002391">
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>Canine Coronavirus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002392 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002392</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus Vaccine-Borrelia Burgdorferi Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002393 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002393">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004897"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012180"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002393</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Coronavirus-Parvovirus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002394 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002394">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001490"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002394</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10514"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002395 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002395">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002393"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002408"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002395</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002396 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002396">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002397"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002396</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2 Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002397 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002397">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001490"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002391"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002397</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10514"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2 Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002398 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002398">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001490"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001526"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002392"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002393"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002398</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10514"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus vaccine-Borrelia Burgdorferi Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002399 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002399">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002392"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002400"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002399</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002400 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002400">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002402"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002400</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002401 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002401">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000752"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001498"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012188"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>horse EEV, VEV, WEV encephalomyelitis and West Nile Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002402 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002402">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002403"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002403 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002403">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002404"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002403</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002404 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002404">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001526"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002404</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002405 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002405">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001490"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002417"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90062"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002405</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10514"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11153"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90062"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002406 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002406">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000654"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002407"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002406</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Measles-Parainfluenza Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002407 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002407">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001526"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002394"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002407</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002408 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002408">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002407"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012180"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002408</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002409 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002409">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002410"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002409</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira CanicolaGrippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002410 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002410">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002411"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002410</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira CanicolaGrippotyphosa-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002411 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002411">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002412"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002411</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002412 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002412">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002393"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002425"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002412</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002413 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002413">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002394"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012180"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002413</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parvovirus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002414 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002414">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002413"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002414</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parvovirus-Rabies Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002415 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002415">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001526"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10512"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002415</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10512"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Hepatitis-Parainfluenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002416 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002416">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000654"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002416</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Measles vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002417 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002417">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012180"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002417</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Parvovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002418 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002418">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000394"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001526"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002418</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>canine parainfluenza-bordetella bronchiseptica vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002419 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002419">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012180"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002419</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>canine parvovirus vaccine-leptospira canicola icterohaemorrhagiae bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002420 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002420">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>equine EEV and WEV encephalomyelitis vaccine-tetanus toxoid</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002421 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>equine rhinopneumonitis-influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002422 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002422</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>equine EEV and WEV encephalomyelitis-influenza vaccine-tetanus toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002423 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002423">
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>equine EEV and WEV encephalomyelitis-influenza-West Nile virus vaccine-tetanus toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002424 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002424">
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        <obo:IAO_0000115>a viral vaccine against horse EEV, WEV, and VEE viral infections</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>horse encephalomyelitis EEV, VEV, and WEV combination vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002425 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002426 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002427 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Immunodeficiency-Leukemia virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002428 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <rdfs:label>equine EEV and WEV encephalomyelitis-rhinopneumonitis vaccine-tetanus toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002429 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002430 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002430">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000752"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002429"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002430</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>equine EEV and WEV encephalomyelitis-rhinopneumonitis-influenza-West Nile Virus vaccine-tetanus toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002431 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002431">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000541"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002401"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1485"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002431</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1485"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>horse EEV, VEV, WEV encephalomyelitis-West Nile Virus Vaccine-Tetanus Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002432 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002432">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000573"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000843"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001465"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002432</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Chlamydia Psittaci vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002433 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002433">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000389"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000843"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002440"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10786"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002433</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10786"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002434 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002434">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002432"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002433"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002434</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002435 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002435">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000573"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002440"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002435</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Chlamydia Psittaci Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002436 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002436">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000389"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002440"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10786"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002436</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10786"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Panleukopenia Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002437 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002437">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000573"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002436"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002437</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002438 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002438">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002437"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002438</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci-Rabies Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002439 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002439">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002436"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002439</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calici-Panleukopenia-Rabies Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002440 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002440">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10334"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11978"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001465"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001487"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001509"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10334"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11978"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002440</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10334"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11978"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline Rhinotracheitis-Calicivirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002441 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002441">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001468"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012162"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002441</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fowl Laryngotracheitis-Mareks Disease vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002442 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002442">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001462"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001520"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_55987"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_641"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002442</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_117565"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_55987"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_641"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Infectious Salmon Anemia Virus Vaccine-Aeromonas Salmonicida-Vibrio Anguillarum-Ordalii-Salmonicida Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002443 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002443">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000985"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001468"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002443</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118>Fowl Pox-Laryngotracheitis Vaccine</obo:IAO_0000118>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>fowlpox-Laryngotracheitis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002444 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002444">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000985"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001468"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012162"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002444</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118>Fowl Pox-Mareks Disease Vaccine</obo:IAO_0000118>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>fowlpox-Mareks Disease vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002445 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002445">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000985"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001468"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002445</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118>Fowl Pox-Mycoplasma Gallisepticum Vaccine</obo:IAO_0000118>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>fowlpox-Mycoplasma Gallisepticum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002446 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002446">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000620"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001523"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002446</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mannheimia Haemolytica-Pasteurella Multocida vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002447 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002447">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002447</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mareks Disease-Newcastle Disease vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002448 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002448">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38170"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001513"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012162"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38170"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002448</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38170"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>chicken Mareks disease-tenosynovitis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002449 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002449">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002451"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002484"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002449</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Distemper-Enteritis Vaccine-Clostridium Botulinum Type C Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002450 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002450">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000393"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002449"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002450</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Distemper-Enteritis Vaccine-Clostridium Botulinum Type C-Pseudomonas Aeruginosa Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002451 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002451">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10792"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002451</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10792"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Enteritis Vaccine-Clostridium Botulinum Type C Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002452 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002452">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000393"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002451"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002452</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
        <oboInOwl:hasDbXref>SNOMEDCT: 55262006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0310936</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Enteritis Vaccine-Clostridium Botulinum Type C-Pseudomonas Aeruginosa Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002453 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002453">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002457"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149539"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002453</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149539"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease-Bronchitis Vaccine-Salmonella Enteritidis Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002454 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002454">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001502"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002454</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis Vaccine-Mycoplasma Gallisepticum Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002455 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002455">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980915"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980915"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002455</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Hirame rhabdovirus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980915"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hirame rhabdovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002456">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000985"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002456</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10261"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease-Fowlpox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002457 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002457">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001502"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002457</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Bronchitis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002458 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002458">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_260963"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002458</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_260963"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle-Paramyxovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002459 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002459">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000990"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_94063"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002459</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_94063"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bovine parainfluenza 3 vaccine-Leptospira Pomona vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002460 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002460">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002461"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002460</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002461 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002461">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001456"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002462"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002461</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002462 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002462">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002463"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002462</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002463 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002463">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001474"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001494"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002463</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10796"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002464 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002464">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002465"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002464</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus-Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-CanicolaGrippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002465 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002465">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002461"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002465</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12845"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Parvovirus-Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae-Leptospira CanicolaGrippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002466 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002466">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002408"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002466</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus-Rabies Virus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002467 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002467">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000329"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001524"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002467</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2099"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Circovirus Vaccine- Mycoplasma Hyopneumoniae Bactin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002468 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002468">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000620"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001456"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002469"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002468</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus-Transmissible Gastroenteritis Vaccine-Bordetella Bronchiseptica-Clostridium Perfringens Type C-Erysipelothrix Rhusiopathiae-Escherichia Coli-Pasteurella Multocida Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002469 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002469">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001505"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002471"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002469</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11149"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus-Transmissible Gastroenteritis Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002470 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002470">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001505"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002470</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11149"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus-Transmissible Gastroenteritis Vaccine-Escherichia Coli Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002471 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002471">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000639"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000963"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002471</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1502"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002472 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002472">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002467"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002472</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome-Circovirus Vaccine-Mycoplasma Hyopneumoniae Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002473 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002473">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001456"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001511"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002473</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome-Parvovirus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002474 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002474">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001474"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001495"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002474</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus Vaccine-Escherichia Coli Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002475 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002475">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001474"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001495"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001505"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002475</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Rotavirus-Transmissible Gastroenteritis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002476 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002476">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001472"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003550"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002476</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies vaccine-Ehrlichia Risticii Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002477 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002477">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000578"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002477</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_36420"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002478 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002478">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002479 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002479">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000329"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002480 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002480">
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>USDA: 4995.22</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Swine Influenza Vaccine-Mycoplasma Hyopneumoniae Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002481 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001457"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_56690"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002481</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_56690"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trichomonas Foetus-Campylobacter Fetus-Leptospira vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002482 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002482">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002393"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002482</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Coronavirus-Parvovirus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002483 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002483">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000752"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001472"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001498"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012188"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11021"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002483</metadata:prefixIRI>
        <obo:IAO_0000115>A horse vaccine that protects against EEE, VEE, WEE, influenza virius infection, and West Nile virus infection. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9796"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11021"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>horse Encephalomyelitis-Influenza-West Nile Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002484 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002484">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10792"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10792"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002484</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_452646"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10792"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mink Distemper-Enteritis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002485 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002485">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001456"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001474"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001494"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002485</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10796"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>porcine parvovirus-erysipelothrix rhusiopathiae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002486 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002486">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001501"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002486</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Virus Diarrhea-Respiratory Syncytial Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002487 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002487">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002403"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002487</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002488 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002488">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002338"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002352"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002488</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052729"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Leptospira Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002489 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002489">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002489</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_731"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Respiratory Syncytial Virus Virus Vaccine-Haemophilus somnus Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002490 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002490">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002354"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002490</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_196"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Haemophilus somnus-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002491 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002491">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002386"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002491</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <oboInOwl:hasDbXref>USDA: 12X1.21</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Modified Live Virus &amp; Avirulent Live Culture Vaccine (USDA: 12X1.21)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002492 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002492">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0002493 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
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        <oboInOwl:hasDbXref>USDA: 16J1.R3</oboInOwl:hasDbXref>
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        <rdfs:label>Fowl Laryngotracheitis-Marek&apos;s Disease Serotype 3, Live Marek&apos;s Disease Vector Vaccine (USDA: 16J1.R3)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002494 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>created according to 
WHO Technical Report Series, No. 927, 2005
Annex 3
Recommendations for the production and control of influenza vaccine (inactivated)</rdfs:comment>
        <rdfs:label>influenza vaccine (whole virion, inactivated)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002495 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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Annex 3
Recommendations for the production and control of influenza vaccine (inactivated)</rdfs:comment>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002496 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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Annex 3
Recommendations for the production and control of influenza vaccine (inactivated)</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/VO_0002497 -->

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        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
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Annex 3
Recommendations for the production and control of influenza vaccine (inactivated)</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/VO_0002499 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002500 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0002501 -->

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        <obo:IAO_0000115>A vaccine that protects against Mycobacterium avium.</obo:IAO_0000115>
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        <rdfs:label>Mycobacterium avium vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0002502 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002502</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that protects against infection with Staphylococcus aureus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002503 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002503">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_2000000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1279"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002503</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Streptococcus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1279"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Streptococcus gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002504 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002504">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1336"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002504</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial gene that is from Streptococcus equi.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1336"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Streptococcus equi gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002505 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002505">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_644"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000589"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_644"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002505</metadata:prefixIRI>
        <obo:IAO_0000115>Aeromonas vaccine that protects against Aeromonas hydrophila infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_644"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Aeromonas hydrophila vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002506 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002506">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000602"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002506</metadata:prefixIRI>
        <obo:IAO_0000115>An Edwardsiella bacterial vaccine that protects against Edwardsiella tarda.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Edwardsiella tarda vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002507 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002507">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002507</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that protects against infections by  Salmonella typhimurium species.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella typhimurium vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002508 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002508">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_594"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002508</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that protects against infections by  Salmonella enterica subsp. enterica serovar Gallinarum.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_594"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella gallinarum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002509 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002509">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149539"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002509</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that protects against infections by Salmonella enterica subsp. enterica serovar Enteritidis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149539"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella enteritidis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002510 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002510">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_633"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000601"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_633"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002510</metadata:prefixIRI>
        <obo:IAO_0000115>A bacterial vaccine that protects against infections by Yersinia pseudotuberculosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_633"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia pseudotuberculosis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002511 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002511">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162145"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162145"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002511</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection of human metapneumovirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162145"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>human metapneumovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002512 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002512">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002512</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection of Human respiratory syncytial virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human respiratory syncytial virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002513 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002513">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5821"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5821"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002513</metadata:prefixIRI>
        <obo:IAO_0000115>a malaria vaccine that protects against malaria caused by Plasmodium berghei.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5821"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium berghei vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002514 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002514">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002514</metadata:prefixIRI>
        <obo:IAO_0000115>a malaria vaccine that protects against malaria caused by Plasmodium yoelii.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5861"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002515 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002515">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000174"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002515</metadata:prefixIRI>
        <obo:IAO_0000115>A protozoan gene that is from Leishmania infantum.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>Leishmania infantum gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002516 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002516">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001384"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002516</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>The mutant strain, with deletion of apxIA gene, obtained in this study offered a level of cross-serovar protection against A. pleuropneumoniae infection in mice and pigs (Reference: PMID: 16930871).</rdfs:comment>
        <rdfs:label>apxIA from Actinobacillus pleuropneumoniae</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4850247; PMID: 16930871</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002517 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002517">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001384"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002517</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>In the intra-peritoneal mouse model, the virulence of the mutant strain decreased at least 100 fold compared with the parent strain. The mutant was evaluated as a potential vaccine using a vaccination-challenge trial. The death number and lung lesion score in the vaccinated pigs given the serovar 1 challenge were obviously lower than those in the unvaccinated pigs</rdfs:comment>
        <rdfs:label>apxIC from Actinobacillus pleuropneumoniae</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 1477456; PMID: 18062275</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002518 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002518">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001384"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002518</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Deletion in ureC and apxIIA genes of Actinobacillus pleuropneumoniae serotype 2 prototype provides attenuation and protection in pigs against challenge with the virulent parent strain of A. pleuropneumoniae</rdfs:comment>
        <rdfs:label>apxIIA from Actinobacillus pleuropneumoniae</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 255959000; PMID: 12438394</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002519 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002519">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001384"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002519</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002520</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae</rdfs:comment>
        <rdfs:label>apxIIC from Actinobacillus pleuropneumoniae</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 52630373; PMID: 10085043</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002520 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002520">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002520</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002519"/>
        <rdfs:comment>In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae</rdfs:comment>
        <rdfs:label>obsolete apxIIC from Actinobacillus pleuropneumoniae</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 52630373; PMID: 10085043</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002521 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002521">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001384"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002521</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain</rdfs:comment>
        <rdfs:label>apxIIIB from Actinobacillus pleuropneumoniae</rdfs:label>
        <rdfs:seeAlso>NCBI_Nucleotide_ID: 470686; PMID: 19887737</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002522 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002522">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001384"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002522</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain</rdfs:comment>
        <rdfs:label>apxIIID from Actinobacillus pleuropneumoniae</rdfs:label>
        <rdfs:seeAlso>NCBI_Nucleotide_ID: 470687; PMID: 19887737</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002523 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002523">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001384"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002523</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A precisely defined DeltaapxIICDeltaapxIVA double-deletion mutant of A. pleuropneumoniae was constructed based on HB04C(-) by transconjugation and counterselection. The results demonstrated that the DeltaapxIICDeltaapxIVA double mutant strain was less virulent than HB04C(-). Despite attenuation of virulence, the DeltaapxIICDeltaapxIVA double mutant remains immunogenic and conferred a similar level of protective immunity to pigs against challenge with a lethal dose of a heterologous fully virulent standard serovar 1 strain of A. pleuropneumoniae</rdfs:comment>
        <rdfs:label>apxIVA from Actinobacillus pleuropneumoniae</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 6671152; PMID: 17767980</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002524 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002524">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001384"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002524</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application</rdfs:comment>
        <rdfs:label>ureC from Actinobacillus pleuropneumoniae</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 303253439; PMID: 12438394</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002525 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002525">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001402"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002525</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An mntA deletion mutant, generated by allelic replacement, in Bacillus anthracis was attenuated and provided protection for guinea pigs against lethal spore dose (60 LD50) of the virulent B. anthracis Vollum strain</rdfs:comment>
        <rdfs:label>mntA from Bacillus anthracis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 7848141; PMID:  16194238</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002526 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002526">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001403"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002526</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002527</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes</rdfs:comment>
        <rdfs:label>actA from Listeria monocytogenes</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 987035; PMID: 12763691</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002527 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002527">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002527</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002526"/>
        <rdfs:comment>An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes</rdfs:comment>
        <rdfs:label>obsolete actA from Listeria monocytogenes</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 987035; PMID: 12763691</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002528 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002528">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001403"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002528</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A plcB mutant, in combination with an actA mutant, is attenuated in mice and induces significant protection from challenge with wild type L. monocytogenes</rdfs:comment>
        <rdfs:label>plcB from Listeria monocytogenes</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 987036; PMID: 12763691</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002529 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002529">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001404"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002529</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A M. avium relA mutant is attenuated in calves and goats. This mutant also elicited an immune response in goats that limited colonization by challenge wild type M. avium</rdfs:comment>
        <rdfs:label>relA from Mycobacterium avium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2717869; PMID:  21565243</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002530 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002530">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002530</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A drrC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>drrC from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 888491; PMID: 14702160</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002531 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002531">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002531</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An fadD26 mutant is attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>fadD26 from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 887603; PMID: 15958066</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002532 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002532">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002532</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Deletion of leuD gene was shown to be highly attenuated. Immunocompetent BALB/c mice vaccinated with the DleuD auxotroph were protected as well as BCG in terms of survival following an intravenous or aerosol challenge with virulent M. tuberculosis</rdfs:comment>
        <rdfs:label>leuD from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 888225; PMID: 10768986</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002533 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002533">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002533</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A lysA mutant, in combination with a secA2 mutation, is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>lysA from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 886960; PMID:  21264335</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002534 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002534">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002534</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A Mce-2 mutant in Mycobacterium tuberculosis is attenuated and provides protection against challenge for mice</rdfs:comment>
        <rdfs:label>mce-2 from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 925014; PMID: 16388878</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002535 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002535">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002535</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A mce-3 mutant in Mycobacterium tuberculosis is attenuated and provides protection against challenge for mice</rdfs:comment>
        <rdfs:label>mce-3 from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 923491; PMID: 16388878</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002536 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002536">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002536</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002537</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>panC from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 885459; PMID: 12219086</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002537 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002537">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002537</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002536"/>
        <rdfs:comment>A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>obsolete panC from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 885459; PMID: 12219086</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002538 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002538">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002538</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002539</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>panD from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 885596; PMID: 12219086</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002539 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002539">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002539</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002538"/>
        <rdfs:comment>A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>obsolete panD from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 885596; PMID: 12219086</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002540 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002540">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002540</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Study evaluated immunogenicity and protection against Mycobacterium tuberculosis in rhesus monkeys with an attenuated M. tuberculosis with a disrupted phoP gene (SO2) as a single-dose vaccine. SO2 treatment showed reduced average lung bacterial counts (1.0 and 1.2 log respectively, compared with 0.4 log for BCG) and significant protective effect by reduction in C-reactive protein levels, body weight loss, and decrease of erythrocyte-associated hematologic parameters (MCV, MCH, Hb, Ht) as markers of inflammatory infection, all relative to non-vaccinated controls</rdfs:comment>
        <rdfs:label>phoP from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 888772; PMID: 19367339</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002541 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002541">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002541</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A proC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis that is equal to the protection induced by the current vaccine BCG</rdfs:comment>
        <rdfs:label>proC from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 887256; PMID: 11160012</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002542 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002542">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002542</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>RD1 and panCD mutants in Mycobacterium tuberculosis were attenuated and provided protection in CD4-deficient mice against an aerosol challenge with virulent M. tuberculosis</rdfs:comment>
        <rdfs:label>RD1 from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 885777; PMID: 16860907</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002543 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002543">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002543</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Gu√©rin vaccination</rdfs:comment>
        <rdfs:label>secA2 from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 885594; PMID: 17671656</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002544 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002544">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11636"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002544</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Reticuloendotheliosis virus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Reticuloendotheliosis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002545 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002545">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002545</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A sigE mutant is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis, more so than the existing vaccine BCG</rdfs:comment>
        <rdfs:label>sigE from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 888751; PMID:  20457786</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002546 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002546">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000164"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002546</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A trpD mutant is highly attenuated in mice and induces more protection from challenge with wild type M. tuberculosis than that induced by the current vaccine BCG</rdfs:comment>
        <rdfs:label>trpD from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 887681; PMID:  11160012</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002547 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002547">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001405"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002547</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. aureus</rdfs:comment>
        <rdfs:label>aroA from Staphylococcus aureus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID:  8614197; PMID: 16714581</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002548 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002548">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002504"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002548</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A vicK mutant is attenuated in mice and induced protection from challenge with wild type S. equi</rdfs:comment>
        <rdfs:label>vicK from Streptococcus equi</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6760966; PMID: 19088917</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002549 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002549">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001406"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002549</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An A. hydrophila aroA mutant is highly attenuated in trout, and a single immunization conferred significant protection from challenge with wild type A. hydrophila</rdfs:comment>
        <rdfs:label>aroA from Aeromonas hydrophila</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID:  4489425; PMID: 9573055</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002550 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002550">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001408"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002550</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>The aroA gene was inactivated by inserting a fragment expressing kanamycin resistance within the coding sequence and challenged in fish. The LD50 for unvaccinated fish was 71. In contrast, the LD50 was 1.8 x 104 in fish vaccinated once and 3 x 105 in fish vaccinated twice</rdfs:comment>
        <rdfs:label>aroA from Aeromonas salmonicida</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4997369; PMID: 8478107</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002551 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002551">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001407"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002551</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002552</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract</rdfs:comment>
        <rdfs:label>aroA from Bordetella bronchiseptica</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2659145; PMID: 12009288</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002552 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002552">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002552</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002551"/>
        <rdfs:comment>Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract</rdfs:comment>
        <rdfs:label>obsolete aroA from Bordetella bronchiseptica</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2659145; PMID: 12009288</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002553 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002553">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001407"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002553</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 x 105 CFU of RB50, the B. Bronchiseptica parent strain.</rdfs:comment>
        <rdfs:label>bscN from Bordetella bronchiseptica</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2662485; PMID:  17452472</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002554 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002554">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001407"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002554</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 x 105 CFU of RB50, the B. Bronchiseptica parent strain</rdfs:comment>
        <rdfs:label>cyaA from Bordetella bronchiseptica</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2661688; PMID: 17452472</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002555 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002555">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001407"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002555</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A dnt mutant in Bordetella bronchiseptica was attenuated and provides protection in guinea pigs against intranasal challenge with strain L3</rdfs:comment>
        <rdfs:label>dnt from Bordetella bronchiseptica</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2661538; PMID:  3182989</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002556 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002556">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001407"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002556</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A trpE mutant, in combination with an aroA mutation, is attenuated in mice and induces significant protection from challenge with wild type B. bronchiseptica</rdfs:comment>
        <rdfs:label>trpE from Bordetella bronchiseptica</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 8515760; PMID: 12694904</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002557 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002557">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001409"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002557</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in mice and induces significant protection from challenge with wild type B. pertussis</rdfs:comment>
        <rdfs:label>aroA from Bordetella pertussis</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 144037; PMID: 2407655</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002558 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002558">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001409"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002558</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A live attenuated B. pertussis vaccine strain BPZE1, developed by deleting dnt gene, protects mice upon a single intranasal administration</rdfs:comment>
        <rdfs:label>dnt from Bordetella pertussis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2666936; PMID:  18762220</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002559 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002559">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001410"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002559</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A flagella-less mutant of Borrelia burgdorferi (HB19Fla-) was attenuated in immunodeficient SCID mice. Mice were challenged 28 days later with virulent strain Sh. 2 and were protected from challenge</rdfs:comment>
        <rdfs:label>fla from Borrelia burgdorferi</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 435009; PMID: 8627071</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002560 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002560">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000793"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002560</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A asp24 mutation in Brucella abortus is attenuated and provides significant protection in mice</rdfs:comment>
        <rdfs:label>asp24 from B. abortus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID:  2353000; PMID: 17664263</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002561 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002561">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001400"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002561</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A bp26 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice</rdfs:comment>
        <rdfs:label>bp26 from B. melitensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 265991532; PMID: 15246618</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002562 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002562">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000793"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002562</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Brucella DeltaexsA mutant showed decreased survival in mice compared to the survival of parental strain S2308. This demonstrated that ExsA is critical for full bacterial virulence. The B. abortus exsA deletion mutant was used as a live vaccine candidate. Challenge experiments revealed that the exsA mutant strain induced superior protective immunity in BALB/c mice compared to the protective immunity induced by strain S19 or RB51</rdfs:comment>
        <rdfs:label>exsA from B. abortus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID:  3787220; PMID: 12183550</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002563 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002563">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001400"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002563</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Unmarked rough B. abortus and B. melitensis deletion mutants of manBA (including manA and manB) were attenuated. These mutants provided protection against virulent Brucella challenge in mice</rdfs:comment>
        <rdfs:label>manA from B. melitensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 260563601; PMID: 16790778</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002564 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002564">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001400"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002564</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Mutants manB and manA were attenuated in Brucella melitensis and provided protection against challenge in mice&apos;s livers</rdfs:comment>
        <rdfs:label>manB from B. melitensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1198671; PMID:  17664263</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002565 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002565">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001400"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002565</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A mucR mutant has a significantly reduced degree of colonization in mice and protects against wild type B. melitensis 16M</rdfs:comment>
        <rdfs:label>mucR from B. melitensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1197075; PMID:  21708998</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002566 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002566">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001400"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002566</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A omp25 mutant is attenuated and provides protection against challenge in mice</rdfs:comment>
        <rdfs:label>omp25 from B. melitensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1196960; PMID: 12151196</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002567 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002567">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001400"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002567</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A omp31 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice</rdfs:comment>
        <rdfs:label>omp31 from B. melitensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 7676420; PMID: 15246618</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002568 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002568">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000793"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002568</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A pgk mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus</rdfs:comment>
        <rdfs:label>pgk from B. abortus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3788256; PMID:  20194591</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002569 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002569">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000793"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002569</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A pgm mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus</rdfs:comment>
        <rdfs:label>pgm from B. abortus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3788847; PMID: 14573645</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002570 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002570">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001400"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002570</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Mice infected with delta purE201 developed only five to eight times normal spleen weight at 1 week p.i. and produced no interleukin-6 in their serum, which is much lower than the mice infected with the parental strain (16M)</rdfs:comment>
        <rdfs:label>purE from B. melitensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1196006; PMID: 8675325</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002571 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002571">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001400"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002571</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A purE/purK mutant of B. melitensis 16M was attenuated in mice when given intraperitoneally. Nine weeks after immunization, mice were protected from challenge with wild type B. melitensis</rdfs:comment>
        <rdfs:label>purK from B. melitensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 20141763; PMID: 7642258</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002572 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002572">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000793"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002572</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A virB2 mutant is attenuated in Brucella melitensis and provides protection in mice</rdfs:comment>
        <rdfs:label>virB2 from B. abortus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3827981; PMID: 17664263</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002573 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002573">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001400"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002573</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>The deletion of vjbR gene in Brucella melitensis strain 16M made a live attenuated vaccine and provided significance protection against mice</rdfs:comment>
        <rdfs:label>vjbR from B. melitensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1198888; PMID: 21530111</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002574 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002574">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000793"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002574</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Deletion of gene znuA attenuates Brucella abortus and this live attenuated vaccine was challenged in mice. These mice showed significantly fewer spenic CFU</rdfs:comment>
        <rdfs:label>znuA from Brucella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3827700; PMID: 16790759</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002575 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002575">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001411"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002575</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>The aroC deletion in the resultant mutant, designated A2ŒîaroC, was confirmed by PCR, Southern hybridization and failure of the mutant to grow in a defined medium without aromatic compounds. The constructed unmarked aroC mutant of B. pseudomallei is attenuated in both BALB/c and C57Bl/6 mice and is able to confer significant protection in C57Bl/6 mice</rdfs:comment>
        <rdfs:label>aroC from Burkholderia pseudomallei</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4899749; PMID: 19323044</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002576 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002576">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001411"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002576</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An asd mutant is highly attenuated in mice. This mutant was also able to protect against acute inhalation melioidosis caused by challenge with wild type B. pseudomallei</rdfs:comment>
        <rdfs:label>asd from Burkholderia pseudomallei</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 2358232; PMID:  21807903</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002577 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002577">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001411"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002577</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Mice that were challenged with a higher dose of mutant 56:65 purM were protected</rdfs:comment>
        <rdfs:label>purM from Burkholderia pseudomallei</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3092877; PMID: 19121696</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002578 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002578">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001411"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002578</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Although 30:93a purN -immunized mice were challenged with a 10-fold higher dose of WT E8, mice were strongly protected and showed no signs of clinical illness until the experiment was terminated</rdfs:comment>
        <rdfs:label>purN from Burkholderia pseudomallei</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3092878; PMID: 19121696</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002579 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002579">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001412"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002579</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A crp mutant is attenuated in zebrafish and catfish that were immunized intramuscularly and intracoelomically, respectively. Six weeks after immunization, both zebrafish and catfish were protected from challenge with wild type E. ictaluri</rdfs:comment>
        <rdfs:label>crp from Edwardsiella ictaluri</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 7962173; PMID: 22015784</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002580 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002580">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001413"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002580</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002581</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>VO:0002582</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%</rdfs:comment>
        <rdfs:label>aroC from Edwardsiella tarda</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 8608790; PMID: 21777261</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002581 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002581">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002581</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002580"/>
        <rdfs:comment>An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%</rdfs:comment>
        <rdfs:label>obsolete aroC from Edwardsiella tarda</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 8608790; PMID: 21777261</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002582 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002582">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002582</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002580"/>
        <rdfs:comment>An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%</rdfs:comment>
        <rdfs:label>obsolete aroC from Edwardsiella tarda</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 8608790; PMID: 21777261</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002583 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002583">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001413"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002583</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An esrB mutant is highly attenuated in fish (turbot), with an LD50 of 10(8.1)cfu/fish. Vaccination with this mutant elicited significant protection from wild type E. tarda</rdfs:comment>
        <rdfs:label>esrB from Edwardsiella tarda</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 8607237; PMID: 17478097</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002584 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002584">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001413"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002584</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroC and esrC mutant is attenuated in zebra fish. This mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 71.3%</rdfs:comment>
        <rdfs:label>esrC from Edwardsiella tarda</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 8607212; PMID: 21777261</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002585 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002585">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001413"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002585</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroC and slyA mutant is attenuated in zebra fish. This mutant is also protective against challenge from wild type E. tarda, resulting in a relative percent survival of 80.1%</rdfs:comment>
        <rdfs:label>slyA from Edwardsiella tarda</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 8608031; PMID: 21777261</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002586 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002586">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000161"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002586</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A carAB mutant is attenuated in turkeys and induces significant protection from challenge with wild type E. coli</rdfs:comment>
        <rdfs:label>carA from Escherichia coli</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 949025; PMID: 8063392</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002587 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002587">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000161"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002587</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A carAB mutant is attenuated in turkeys and induces significant protection from challenge with wild type E. coli</rdfs:comment>
        <rdfs:label>carB from Escherichia coli</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 944775; PMID: 8063392</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002588 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002588">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000161"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002588</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A ler deletion mutant derived from wild-type EHEC O157:H7 86-24 was constructed by use of suicide vector pCVD442. Following challenge of 7-day-old suckling mice with O157:H7 EDL933, 75.2% born to group B mothers (immunized with F25) sur- vived, as did 83.0% born to group C mothers (immunized with F105). The surviving suckling mice consistently gained body weight. Only 16.8% of sucking mice born to control group mice survived the challenge</rdfs:comment>
        <rdfs:label>ler from Escherichia coli</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 8219269; PMID: 19682616</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002589 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002589">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000161"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002589</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Deletion of waaL results in a strain that stimulates enhanced urothelial cytokine secretion, which is an enhanced innate immune response. Inoculation with the vaccine strain protected mice against challenge with a broad range of clinical uropathogenic E. coli isolates and produced immunity that lasted &gt;=8 weeks.</rdfs:comment>
        <rdfs:label>rfaL from Escherichia coli</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 948148; PMID: 19522648</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002590 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002590">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002590</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>There was a deletion in gene capB of F. tularensis live vaccine strain. LVS capB, while much less virulent than LVS, induces potent protective immunity against lethal LVS i.n. challenge in mice, comparable to that induced by LVS</rdfs:comment>
        <rdfs:label>capB from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3952402; PMID:  20643859</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002591 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002591">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002591</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A clpB mutant in Francisella tularensis subspecies tularensis strain SCHU S4 was attenuated and provided protection against aerosol challenge in mice</rdfs:comment>
        <rdfs:label>clpB from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3192509; PMID: 20018266</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002592 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002592">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002592</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A FTL0552 mutant in Francisella tularensis was attenuated and provided partial protection in mice against challenge with a lethal dose of the virulent SchuS4 strain when compared to naive mice</rdfs:comment>
        <rdfs:label>FTL0552 from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3952730; PMID: 18613792]</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002593 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002593">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002593</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An FTT0918 mutant showed significantly reduced virulence in mice. Mice that recovered from infection with the mutant were protected 2 months later from challenge with wild type F. tularensis</rdfs:comment>
        <rdfs:label>FTT0918 from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3191684; PMID: 16299332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002594 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002594">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002594</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A galU mutant is attenuated in mice, with only transient weight loss observed. Two months after inoculation, mice were challenge with wild type F. tularensis and were protected, once again only experiencing transient weight loss</rdfs:comment>
        <rdfs:label>galU from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3191600; PMID: 21819572</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002595 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002595">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002595</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaA mutant is highly attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS</rdfs:comment>
        <rdfs:label>guaA from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3951701; PMID: 19368784</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002596 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002596">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002596</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaB mutant is attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS</rdfs:comment>
        <rdfs:label>guaB from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3952496; PMID: 19368784</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002597 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002597">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002597</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Intranasal vaccination with KKF235 (F. tularensis subsp. novicida mutant (DeltaiglB) ) protected mice from subsequent homotypic challenge with U112 as well as heterotypic challenge with F. tularensis subsp. holarctica (LVS). Most significantly, oral immunization with KKF235 protected mice from a highly lethal subsp. tularensis (SCHU S4) pulmonary challenge</rdfs:comment>
        <rdfs:label>iglB from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4548125; PMID: 20016043</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002598 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002598">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002598</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An iglC mutant is highly attenuated in mice. Inoculated mice were challenged 30 days later with wild type F. tularensis and were highly protected</rdfs:comment>
        <rdfs:label>iglC from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4548124; PMID: 16552035</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002599 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002599">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002599</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A purMCD mutant in Francisela tularensis was attenuated. A low dosage of F. tularensis LVS delta purMCD mutant provided protection against challenge in mice</rdfs:comment>
        <rdfs:label>purC/purD from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3952576; PMID:  16861631</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002600 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002600">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002600</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Mice, which had been immunized with at least 6.95 x 103 cfu of F. tularensis U112 purF::Cm, were protected against the subsequent F. tularensis subspecies novicida challenge.</rdfs:comment>
        <rdfs:label>purF from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4548578; PMID: 16930871</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002601 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002601">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002601</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A purMCD mutant in Francisella tularensis was attenuated. A low dose of the F. tularensis LVS delta purMCD mutant provided protection against subsequent lethal challenge with the LVS parental strain</rdfs:comment>
        <rdfs:label>purM from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3952575; PMID:  16861631</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002602 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002602">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002602</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>C57BL/6 mice were vaccinated intranasally (i.n.) with the sodB(Ft) mutant and challenged i.n. with lethal doses of F. tularensis SchuS4. SodB(Ft) vaccinated mice following SchuS4 challenge exhibited significantly reduced bacterial burden in lungs, liver and spleen, regulated production of pro-inflammatory cytokines and less severe histopathological lesions compared to the LVS vaccinated mice. The sodB(Ft) vaccination induced a potent humoral immune response and protection against SchuS4 required both CD4 and CD8 T cells in the vaccinated mice</rdfs:comment>
        <rdfs:label>sodB from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4548021; PMID: 18692537</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002603 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002603">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002603</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A sodC mutant in Francisella tularensis subspecies holarctica was attenuated and provided protection and cleared the infection against lethal challenge in nearly 50% of the mice infected with the delta-sodC mutant.</rdfs:comment>
        <rdfs:label>sodC from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 1314283; PMID: 19684141</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002604 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002604">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002604</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A wbtA mutant in Francisella tularensis was attenuated and provided protection in mice against challenge with an otherwise lethal dose of either F. tularensis LVS or a fully virulent clinical isolate of F. tularensis type B</rdfs:comment>
        <rdfs:label>wbtA from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3191939; PMID: 17296751</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002605 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002605">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001414"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002605</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A wbtI mutant is attenuated in mice. The mutant protected against a low dose challenge with the parental strain, but was less effective against higher doses. However, increasing the immunization dose increased the resistance to higher challenge doses</rdfs:comment>
        <rdfs:label>wbtI from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 5522688; PMID: 17768257</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002606 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002606">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002606</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in mice and induced significant protection after two doses from challenge with wild type M. haemolytica</rdfs:comment>
        <rdfs:label>aroA from Mannheimia haemolytica</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 451485; PMID: 7839583</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002607 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002607">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001416"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002607</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An lpd mutant is highly attenuated in chickens and induces significant protection from challenge with wild type M. gallisepticum</rdfs:comment>
        <rdfs:label>lpd from Mycoplasma gallisepticum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1089767; PMID: 18342996</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002608 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002608">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002608</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A metH mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:label>metH from Neisseria meningitidis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 903064; PMID:  14688114</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002609 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002609">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002609</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An rfaF mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:label>rfaF from Neisseria meningitidis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 904029; PMID:  14688114</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002610 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002610">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002610</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002611</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:label>siaD from Neisseria meningitidis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 903210; PMID:  14688114</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002611 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002611">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002611</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002610"/>
        <rdfs:comment>A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:label>obsolete siaD from Neisseria meningitidis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 903210; PMID:  14688114</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002612 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002612">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001418"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002612</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in calves and induces significant protection from challenge with wild type P. multocida</rdfs:comment>
        <rdfs:label>aroA from Pasteurella multocida</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 581456; PMID: 17875632</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002613 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002613">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001419"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002613</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. typhi Ty2</rdfs:comment>
        <rdfs:label>aroA from Salmonella Typhi</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1068996; PMID: 3039297</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002614 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002614">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001419"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002614</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002615</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain &quot;CVD 908&quot;</rdfs:comment>
        <rdfs:label>aroC from Salmonella Typhi</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1069415; PMID: 17582563</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002615 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002615">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002615</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002614"/>
        <rdfs:comment>Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain &quot;CVD 908&quot;</rdfs:comment>
        <rdfs:label>obsolete aroC from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1069415; PMID: 17582563</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002616 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002616">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001419"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002616</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Inactivation of AroD results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain &quot;CVD 908&quot;</rdfs:comment>
        <rdfs:label>aroD from Salmonella Typhi</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1070649; PMID: 17582563</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002617 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002617">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002617</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002618</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:label>asd from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 267995764; PMID:  20799091</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002618 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002618">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002618</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002617"/>
        <rdfs:comment>An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:label>obsolete asd from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 267995764; PMID:  20799091</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002619 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002619">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002619</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An atpA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>atpA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 301160399; PMID: 19649318</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002620 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002620">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002620</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A cbiA mutant, in combination with a cobS mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis</rdfs:comment>
        <rdfs:label>cbiA from Salmonella Gallinarum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6923268; PMID: 20153354</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002621 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002621">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001422"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002621</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective, and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis</rdfs:comment>
        <rdfs:label>clpP from Salmonella Enteritidis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6950532; PMID: 21807911</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002622 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002622">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002622</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002623</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>VO:0002624</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>clpP from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1251968; PMID: 2496146</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002623 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002623">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002623</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002622"/>
        <rdfs:comment>A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>obsolete clpP from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1251968; PMID: 2496146</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002624 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002624">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002624</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002622"/>
        <rdfs:comment>A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>obsolete clpP from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1251968; PMID: 2496146</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002625 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002625">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002625</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis</rdfs:comment>
        <rdfs:label>cobS from Salmonella Gallinarum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6923296; PMID: 20153354</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002626 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002626">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002626</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs</rdfs:comment>
        <rdfs:label>cpxA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1255585; PMID: 15542179</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002627 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002627">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002627</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A cpxR mutant, in combination with a lon mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum</rdfs:comment>
        <rdfs:label>cpxR from Salmonella Gallinarum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6923307; PMID: 20487719</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002628 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002628">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002628</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>crp from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1254989; PMID: 3316029</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002629 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002629">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002629</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A crp mutant is attenuated in mice and induces significant protection from challenge with wild type S. gallinarum</rdfs:comment>
        <rdfs:label>crp from Salmonella Gallinarum</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 46811321; PMID: 17488512</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002630 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002630">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002630</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>cya from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 581756; PMID: 3316029</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002631 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002631">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001422"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002631</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A fliC mutant, in combination with a guaB mutant, is attenuated in mice and chickens and induces significant protection from challenge with wild type S. enterica</rdfs:comment>
        <rdfs:label>fliC from Salmonella Enteritidis</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 119351647; PMID: 17261603</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002632 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002632">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002632</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaBA, clpP, and fliD mutant (CVD 1923) is attenuated in mice after oral immunization. This mutant is also protective, with a vaccine efficacy of 80% in mice against wild type challenge from Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>fliD from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1253481; PMID: 21807911</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002633 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002633">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001419"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002633</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A gal E mutant in strain Ty2 was isolated, attenuated, and protected mice against lethal challenge</rdfs:comment>
        <rdfs:label>galE from Salmonella Typhi</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1067209; PMID: 1092768</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002634 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002634">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001422"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002634</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective in mice and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis</rdfs:comment>
        <rdfs:label>guaA from Salmonella Enteritidis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6948075; PMID: 21807911</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002635 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002635">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002635</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002636</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>guaA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1254032; PMID: 21807911</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002636 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002636">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002636</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002635"/>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>obsolete guaA from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1254032; PMID: 21807911</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002637 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002637">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002637</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002638</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>guaB from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1254033; PMID: 21807911</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002638 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002638">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002638</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002637"/>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>obsolete guaB from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1254033; PMID: 21807911</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002639 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002639">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001422"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002639</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002640</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica</rdfs:comment>
        <rdfs:label>guaB from Salmonella Enteritidis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6949287; PMID: 17261603</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002640 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002640">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002640</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002639"/>
        <rdfs:comment>A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica</rdfs:comment>
        <rdfs:label>obsolete guaB from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6949287; PMID: 17261603</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002641 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002641">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002641</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs</rdfs:comment>
        <rdfs:label>gyrA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1253794; PMID: 15542179</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002642 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002642">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002642</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Oral immunization with the Salmonella hfq deletion mutant efficiently protects mice against subsequent oral challenge with virulent strain of Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>hfq from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1255887; PMID: 21347426</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002643 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002643">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002643</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A htrA mutant in Salmonella typhimurium is attenuated and provides protection in mice against an oral challenge with virulent S. typhimurium SL1344</rdfs:comment>
        <rdfs:label>htrA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 301156836; PMID: 1584006]</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002644 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002644">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002644</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A lon mutant, in combination with a cpxR mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum</rdfs:comment>
        <rdfs:label>lon from Salmonella Gallinarum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6923289; PMID: 20487719</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002645 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002645">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002645</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An lppA mutant, in combination with an lppB/msbB mutation, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>lppA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 323129647; PMID: 17997275</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002646 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002646">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002646</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002647</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>lppB from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 267993263; PMID: 17997275</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002647 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002647">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002647</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002646"/>
        <rdfs:comment>An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>obsolete lppB from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 267993263; PMID: 17997275</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002648 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002648">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002648</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002649</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium</rdfs:comment>
        <rdfs:label>msbB from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 4104731; PMID: 17997275</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002649 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002649">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002649</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002648"/>
        <rdfs:comment>An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium</rdfs:comment>
        <rdfs:label>obsolete msbB from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 4104731; PMID: 17997275</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002650 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002650">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002650</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>In a pig infection experiment including two oral immunizations with SalmoporcDeltaompD (OmpD, nmpC) and challenge with a multiresistant S. enterica serovar Typhimurium DT104 clinical isolate, we confirmed the protective efficacy of SalmoporcDeltaompD in pigs, showing a significant reduction of both clinical symptoms and colonization of lymph nodes and intestinal tract</rdfs:comment>
        <rdfs:label>nmpC from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 517159; PMID: 17296750</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002651 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002651">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002651</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A nuoG mutant is attenuated in chickens and induced significant protection from challenge with wild type S. Gallinarum</rdfs:comment>
        <rdfs:label>nuoG from Salmonella Gallinarum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6924283; PMID: 9682335</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002652 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002652">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002652</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An ompR mutant is attenuated in mice after oral challenge. Twenty eight days after immunization, mice were challenged with wild type S. typhimurium and were significantly protected</rdfs:comment>
        <rdfs:label>ompR from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 301160045; PMID: 2543631</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002653 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002653">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001419"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002653</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Three S. typhi deletion mutants (phoP, rpoS, and rpoS-phoP double mutant) were constructed and characterized with respect to invasiveness, virulence, and protective immune response compared with wild-type Ty2. All S. typhi mutants showed an increase in the specific serum IgG levels and T-cell-mediated immunity, and showed equal protection abilities against a wild-type Ty2 challenge after two rounds of immunization in BALB/c mice</rdfs:comment>
        <rdfs:label>phoP from Salmonella Typhi</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1071307; PMID: 17725620</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002654 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002654">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002654</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A poxA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>poxA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1255870; PMID: 9826331</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002655 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002655">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002655</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum</rdfs:comment>
        <rdfs:label>relA from Salmonella Gallinarum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6922678; PMID: 21046347</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002656 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002656">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002656</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An rfc mutant, in combination with an asd mutation, is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>rfc from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 267993210; PMID: 20799091</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002657 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002657">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002657</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs</rdfs:comment>
        <rdfs:label>rpoB from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 255679; PMID: 15542179</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002658 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002658">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002658</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Immunizations with Salmonella typhimurium rpoS and rpoS aroA mutants protected susceptible BALB/c mice against subsequent oral challenge with virulent S. typhimurium. When administered orally or intraperitoneally, rpoS derivatives of the mouse-virulent S. typhimurium strains, C52 and SL1344, were highly attenuated and were efficient single-dose live vaccines</rdfs:comment>
        <rdfs:label>rpoS from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 301159483; PMID: 8899717</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002659 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002659">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002659</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A ruvB mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>ruvB from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1253415; PMID: 20670908</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002660 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002660">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001420"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002660</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum</rdfs:comment>
        <rdfs:label>spoT from Salmonella Gallinarum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 6924903; PMID: 21046347</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002661 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002661">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002661</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A surA mutant (BRD1115) is attenuated in BALB/c mice and induces protection from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>surA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1251610; PMID: 10678914</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002662 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002662">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002662</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A tolA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>tolA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 301157338; PMID: 19118362</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002663 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002663">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002663</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A trxA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>trxA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 301160436; PMID: 19884329</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002664 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002664">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002664</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A wecA mutant (DSM645) is attenuated in C57BL/6J mice through i.p. and oral immunization. This mutant also protects against challenge with S. typhimurium strains TML and SL1344 30 days after immunization</rdfs:comment>
        <rdfs:label>wecA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 20140863; PMID: 22025511</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002665 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002665">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002665</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:label>znuA from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 253412; PMID: 21219981</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002666 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002666">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002666</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:label>znuB from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1253414; PMID: 21219981</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002667 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002667">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001421"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002667</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:label>znuC from Salmonella Typhimurium</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1253413; PMID: 21219981</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002668 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002668">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002668</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002669</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>VO:0002670</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>VO:0002671</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>aroA from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1077373; PMID: 7927802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002669 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002669">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002669</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002668"/>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>obsolete aroA from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1077373; PMID: 7927802</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002670 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002670">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002670</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002668"/>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>obsolete aroA from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1077373; PMID: 7927802</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002671 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002671">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002671</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002668"/>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>obsolete aroA from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1077373; PMID: 7927802</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002672 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002672">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002672</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002673</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>aroD from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1078189; PMID: 8356844</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002673 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002673">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002673</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002672"/>
        <rdfs:comment>An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>obsolete aroD from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1078189; PMID: 8356844</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002674 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002674">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002674</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An envZ mutant (SC433) is greatly decreased in virulence in macaque monkeys, though some mild clinical signs were still recorded. This mutant is also highly protective against a challenge of wild type S. flexneri delivered 1 month after inoculation</rdfs:comment>
        <rdfs:label>envZ from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4207729; PMID: 1887672</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002675 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002675">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002675</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002676</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>icsA/virG from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1238021; PMID: 7927802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002676 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002676">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002676</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002675"/>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>obsolete icsA/virG from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1238021; PMID: 7927802</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002677 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002677">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002677</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A virG, senA, senB, and msbB2 mutant (WRSs3) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs3 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>msbB2 from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3670926; PMID: 19932216]</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002678 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002678">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002678</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002679</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>senA from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3671021; PMID: 19932216</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002679 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002679">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002679</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002678"/>
        <rdfs:comment>A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>obsolete senA from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3671021; PMID: 19932216</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002680 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002680">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002680</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002681</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>senB from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3668265; PMID: 19932216</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002681 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002681">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002681</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002680"/>
        <rdfs:comment>A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>obsolete senB from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3668265; PMID: 19932216</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002682 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002682">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002682</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002683</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei</rdfs:comment>
        <rdfs:label>virG from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3670887; PMID: 9712824</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002683 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002683">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002683</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002682"/>
        <rdfs:comment>A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei</rdfs:comment>
        <rdfs:label>obsolete virG from Shigella</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3670887; PMID: 9712824</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002684 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002684">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001423"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002684</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A hemA mutant is highly attenuated in mice and rabbits and induces protection from challenge with wild type V. cholerae in rabbits</rdfs:comment>
        <rdfs:label>hemA from Vibrio cholerae</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 12656010; PMID: 16102875</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002685 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002685">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001425"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002685</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in mice, and after 3 doses induces significant protection from challenge with wild type Y. enterocolitica</rdfs:comment>
        <rdfs:label>aroA from Yersinia enterocolitica</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4713234; PMID: 2777382</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002686 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002686">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001425"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002686</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A htrA mutant in Yersinia enterocolitica was attenuated and provided partial protection against challenge in mice</rdfs:comment>
        <rdfs:label>htrA from Yersinia enterocolitica</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4715899; PMID: 8675311</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002687 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002687">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001425"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002687</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A ompR mutant in Yersinia enterocolitica was attenuated and provided a partial protection from challenge in mice</rdfs:comment>
        <rdfs:label>ompR from Yersinia enterocolitica</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4716266; PMID: 9711851</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002688 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002688">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001425"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002688</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A sodA mutant in Yersinia enterocolitica was highly attenuated and mice immunized with a single oral dose of the mutant strain were protected against a lethal oral-challenge infection with wild-type Y. enterocolitica</rdfs:comment>
        <rdfs:label>sodA from Yersinia enterocolitica</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 4716532; PMID: 10496939</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002689 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002689">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001426"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002689</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>guaA from Yersinia pestis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1146310; PMID: 0096773</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002690 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002690">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001426"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002690</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>guaB from Yersinia pestis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1146309; PMID: 0096773</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002691 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002691">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001426"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002691</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An IpxM mutant is attenuated in mice and guinea pigs. This mutant also conferred modest protection from challenge with wild type Y. pestis in Balb/c mice and significant protection in guinea pigs and outbred mice</rdfs:comment>
        <rdfs:label>ipxM from Yersinia pestis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1174901; PMID: 17913308</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002692 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002692">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001426"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002692</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An nlpD mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>nlpD from Yersinia pestis</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 224483371; PMID: 19759820</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002693 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002693">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001426"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002693</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A pcm mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>pcm from Yersinia pestis</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 224483370; PMID: 14742535</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002694 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002694">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001426"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002694</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>smpB from Yersinia pestis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1173949; PMID: 20065026</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002695 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002695">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001426"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002695</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>ssrA from Yersinia pestis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1173948; PMID: 20065026</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002696 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002696">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001426"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002696</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A yopH mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>yopH from Yersinia pestis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1172712; PMID: 17652523</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002697 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002697">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001427"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002697</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A phoP mutant in Yersinia pseudotuberculosis (Yptb) was attenuated and provided protection against oral challenge with virulent Yptb in mice</rdfs:comment>
        <rdfs:label>phoP from Yersinia pseudotuberculosis</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2956268; PMID: 17194509</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002698 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002698">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001428"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002698</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in rainbow trout and induces significant protection from challenge with wild type Y. ruckeri</rdfs:comment>
        <rdfs:label>aroA from Yersinia ruckeri</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 15420539; PMID: 16083447</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002699 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002699">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001424"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002699</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A thymidine kinase-deficient mutant (B8-D53) showed no detectable thymidine kinase-inducing activity and was attenuated in calves. B8-D53 also induced protection from challenge with wild type BHV-1</rdfs:comment>
        <rdfs:label>UL23 from Bovine herpesvirus 1</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1487380; PMID: 2994602</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002700 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002700">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001424"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002700</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A deletion of BHV-1 gE gene in strain A is considered as a live attenuated vaccine. After challenge, vaccinated calves were protected against disease and virus shedding was reduced</rdfs:comment>
        <rdfs:label>US8 from Bovine herpesvirus 1</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1487407; PMID: 8023552</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002701 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002701">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001429"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002701</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein G deletion in bovine respiratory syncytial virus(rBRSV) and recombinant rBRSV was attenuated and provided protection against a BRSV challenge infection in calves</rdfs:comment>
        <rdfs:label>glycoprotein G from Bovine Respiratory Syncytial Virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1489813; PMID: 12414977</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002702 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002702">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001430"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002702</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An N269A/Q mutation in the E(rns) protein created an attenuated mutant in swine. This mutant was able to induce effective protection in swine against challenge with wild type CSFV</rdfs:comment>
        <rdfs:label>E(rns) from Classical swine fever virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 130457; PMID: 17904607</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002703 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002703">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001430"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002703</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An N to A amino acid substitution was made in the N594 site of the E1 glycoprotein, resulting in attenuation of the virus in swine. This attenuated virus induced protection against challenge with wild type CSFV</rdfs:comment>
        <rdfs:label>E1 from Classical swine fever virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 325461; PMID: 19203774</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002704 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002704">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001430"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002704</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A E2 mutant in Classical swine fever virus is attenuated and provides protection in pigs after oronasal vaccination (not intradermal vaccination) against lethal challenge dose of CSFV strain Eystrup</rdfs:comment>
        <rdfs:label>E2 gene from Classical swine fever virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 920146; PMID: 15837238</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002705 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002705">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001431"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002705</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein E mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice</rdfs:comment>
        <rdfs:label>gE from Equid herpesvirus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 330789; PMID: 17085880</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002706 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002706">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001431"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002706</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein I mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice</rdfs:comment>
        <rdfs:label>gI from Equid herpesvirus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 330788; PMID: 17085880</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002707 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002707">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002707</metadata:prefixIRI>
        <obo:IAO_0000115>A thymidine kinase-deficient mutant (PR1) is attenuated in mice and induced significant protection from challenge with wild type EHV-1 5 weeks after vaccination. In foals, PR1 also showed attenuation; however, the mutant induced only partial protection from challenge with EHV-1</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>TK from Equid herpesvirus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 59214; PMID: 16930871</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002708 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002708">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001432"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002708</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A thymidine kinase-deficient mutant (C7301dlTK) is attenuated in cats and induced significant protection from wild type FHV-1 4 weeks after vaccination</rdfs:comment>
        <rdfs:label>UL23 from Feline herpesvirus 1</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 8658565; PMID: 8645090</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002709 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002709">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001433"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002709</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Feline immunodeficiency virus (FIV) made defective in the accessory gene ORF-A were previously shown to be greatly attenuated in its ability to replicate in lymphocytes but to grow normally or near normally in other cell types. 3/9 vaccinees (cats) showed no evidence of the challenge virus over a 15-month observation period. In the other vaccinees, the challenge virus was predominant for various periods of time, but pre-existing viral loads and CD4 lymphocyte counts were either unaffected or altered only marginally and transiently</rdfs:comment>
        <rdfs:label>ORF-A from Feline immunodeficiency virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1724707; PMID: 15680433</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002710 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002710">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001433"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002710</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A vif mutant in feline immunodeficiency virus was attenuated and FIV-pPPR delta vif proviral DNA protected cats against challenge with the homologous FIV-PPR biological isolate.</rdfs:comment>
        <rdfs:label>vif from Feline immunodeficiency virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1724709; PMID: 10891409</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002711 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002711">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001434"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002711</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>3a from Feline infectious peritonitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 10040181; PMID: 15047802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002712 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002712">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001434"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002712</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>3b from Feline infectious peritonitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 10040182; PMID: 15047802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002713 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002713">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001434"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002713</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>3c from Feline infectious peritonitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 10040183; PMID: 15047802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002714 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002714">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001434"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002714</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>7a from Feline infectious peritonitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 10040187; PMID: 15047802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002715 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002715">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001434"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002715</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>7b from Feline infectious peritonitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 10040188; PMID: 15047802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002716 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002716">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002716</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A UL0 mutant in infectious laryngotracheitis virus (ILTV) was attenuated. Chickens immunized with UL0-negative ILTV were protected from clinical disease after subsequent infection with virulent ILTV</rdfs:comment>
        <rdfs:label>UL0 from Gallid herpesvirus 1</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3239037; PMID: 14645915</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002717 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002717">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002717</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A thymidine-kinase mutant is attenuated in chickens and induced protection from challenge with wild type GHV-1</rdfs:comment>
        <rdfs:label>UL23 from Gallid herpesvirus 1</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3239035; PMID: 12021870</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002718 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002718">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001435"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002718</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A UL47 mutant in avian infectious laryngotracheitis virus is attenuated and provides protection in chicken against subsequent challenge infection with virulent ILTV</rdfs:comment>
        <rdfs:label>UL47 from Gallid herpesvirus 1</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3239064; PMID: 17325345</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002719 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002719">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001436"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002719</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Researchers generated a series of woodchuck hepatitis virus (WHV) X mutants. Woodchucks inoculated with X mutants, including those with no serologic evidence of infection, were protected from later challenge with infectious Woodchuck Hepatitis Virus, suggesting previous infection with resulting protective immunity</rdfs:comment>
        <rdfs:label>HBVgp3 X protein from Hepatitis B virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 944566; PMID: 11714744</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002720 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002720">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001437"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002720</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>KOS-gDA3C is attenuated with mutations in gD gene in causing skin lesions at the inoculation and zosteriform sites, yet it is as effective as rKOS-gDA3C in protecting mice against HSV-1 challenge</rdfs:comment>
        <rdfs:label>gD from Herpes simplex virus type 1 and 2</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 19548971; PMID: 18243431</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002721 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002721">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001437"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002721</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A gH mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1</rdfs:comment>
        <rdfs:label>gH from Herpes simplex virus type 1 and 2</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 138315; PMID: 8289395</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002722 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002722">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001454"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002722</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A live-attenuated HSV-2 ICP0 virus provides significant protection against wild-type HSV-2 (MS strain) challenge in mice</rdfs:comment>
        <rdfs:label>iCP0 from Herpes simplex virus type 1 and 2</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1487289; PMID:  21412438</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002723 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002723">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001437"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002723</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A thymidine kinase-deficient (TK) mutant was found to be attenuated in mice. This mutant induced complete protection from challenge with wild type HSV</rdfs:comment>
        <rdfs:label>TK from Herpes simplex virus type 1 and 2</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2703374; PMID: 212476</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002724 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002724">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001437"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002724</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A UL29 mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1</rdfs:comment>
        <rdfs:label>UL29 from Herpes simplex virus type 1 and 2</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2703458; PMID: 8289372</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002725 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002725">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001437"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002725</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An HSV-1 gE (Us8) deletion strain, NS-gEnull, was used as a live attenuated vaccine. After HSV-1 challenge, latent virus was recovered by DRG explant cocultures from &lt;10% of vaccinated mice compared with 100% of mock-vaccinated mice</rdfs:comment>
        <rdfs:label>US8 from Herpes simplex virus type 1 and 2</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2703448; PMID: 18562543</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002726 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002726">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001438"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002726</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A G mutant is attenuated in African green monkeys and induces protection from challenge with wild type HMPV</rdfs:comment>
        <rdfs:label>G protein from Human metapneumovirus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 75549950; PMID: 16160190</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002727 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002727">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001438"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002727</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An M2-2 mutant is attenuated in African green monkeys and induced protection from challenge with wild type HMPV</rdfs:comment>
        <rdfs:label>M2-2 from Human metapneumovirus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 75549952; PMID: 16160190</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002728 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002728">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001439"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002728</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An M2-2 mutant of human respiratory syncytial virus A2 is attenuated in African green monkeys. When challenged with wild type RSV, two doses provided complete protection against challenge in the lower respiratory tract and a significant reduction of the challenge virus in the upper respiratory tract</rdfs:comment>
        <rdfs:label>M2-2 from Human Respiratory Syncytial Virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 81925031; PMID: 12922094</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002729 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002729">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001440"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002729</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A mutation in the non-virion protein of IHNV causes attenuated growth in rainbow trout and is able to provide significant protection from subsequent challenge with wild type IHNV</rdfs:comment>
        <rdfs:label>NV from Infectious Hematopoietic Necrosis Virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1489849; PMID: 15047826</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002730 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002730">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000185"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002730</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Mutant influenza virus that lacks the transmembrane and cytoplasmic tail domains of M2 (M2 knockout [M2KO]) from Influenza A virus (A/Puerto Rico/8/34(H1N1)) is attenuated in both cell culture and mice. Mice intranasally vaccinated with M2KO virus developed protective immune responses and survived a lethal challenge with the wild-type virus, suggesting that the M2KO virus has potential as a live attenuated vaccine</rdfs:comment>
        <rdfs:label>M2 from Influenza virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 956528; PMID: 19321619</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002731 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002731">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000185"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002731</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Intranasal inoculation of mice, pigs, horses, and macaques with NS1-modified influenza virus strains induced robust humoral and cellular immune responses, and generated immune protection against challenge with wild-type virus</rdfs:comment>
        <rdfs:label>NS1 from Influenza virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 505039; PMID: 19768406</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002732 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002732">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001441"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002732</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A mutation in the GP5 protein attenuates HP-PRRSV in piglets. This mutant (HuN4-F112) induces protection against challenge with wild type HP-PRRSV</rdfs:comment>
        <rdfs:label>GP5 protein from Porcine respiratory and reproductive syndrome virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 149389584; PMID: 19339125</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002733 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002733">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001442"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002733</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein E mutant, in combination with UL23 and glycoprotein G mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV</rdfs:comment>
        <rdfs:label>glycoprotein E from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 307634504; PMID: 12488067</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002734 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002734">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001442"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002734</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV</rdfs:comment>
        <rdfs:label>glycoprotein G from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 15422177; PMID: 12488067</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002735 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002735">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001442"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002735</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein M, gM, deletion in pseudorabies virus was attenuated and induced protection in piglets against intranasal challenge with 108 p.f.u. of the highly virulent PrV strain NIA-3</rdfs:comment>
        <rdfs:label>glycoprotein M from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 1478255; PMID: 9292000</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002736 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002736">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001442"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002736</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky&apos;s disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3</rdfs:comment>
        <rdfs:label>gp50 from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2952548; PMID: 8178562</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002737 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002737">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001442"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002737</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky&apos;s disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3</rdfs:comment>
        <rdfs:label>gp63 from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2952540; PMID: 8178562</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002738 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002738">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001442"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002738</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV</rdfs:comment>
        <rdfs:label>UL23 from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2952559; PMID: 12488067</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002739 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002739">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001442"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002739</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A UL50 mutant is attenuated in pseudorabies virus and induces significant protection in pigs from challenge with the highly virulent NIA-3 strain of PrV</rdfs:comment>
        <rdfs:label>UL50 from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2952537; PMID: 9228681</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002740 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002740">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001442"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002740</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Researchers intranasally inoculated pigs, the natural host of this virus, with mutant PRV strains in which the genes encoding the protein kinase (US3) proteins were inactivated. After challenge infection with the virulent PRV strain NIA-3, no virus was excreted by wt PRV- and PK- mutant-immunized animals, indicating complete protective immunity</rdfs:comment>
        <rdfs:label>US3 from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 2952561; PMID: 7975253</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002741 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002741">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001443"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002741</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein G mutant in rabies virus is attenuated. After a one-dose intramuscular vaccination, the ERAg3m virus protected 100% of mice and hamsters from lethal challenge. In co-infections, using a lethal dose of street rabies virus mixed with ERAg3m, 100% of hamsters and 90% of mice survived and were protected against subsequent infection</rdfs:comment>
        <rdfs:label>glycoprotein G from Rabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1489856; PMID: 21514343</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002742 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002742">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001443"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002742</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A P gene mutant is attenuated in mice and induces significant protection from challenge with wild type Rabies virus</rdfs:comment>
        <rdfs:label>P protein from Rabies virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 291220682; PMID: 15896403</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002743 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002743">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001444"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002743</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An E mutant is attenuated in hamsters and induces significant protection from challenge with wild type SARS</rdfs:comment>
        <rdfs:label>E from SARS-CoV</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1489671; PMID: 18463152</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002744 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002744">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001445"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002744</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A SIV nef mutant is attenuated in rhesus monkeys and induces protection from challenge with wild type SIV</rdfs:comment>
        <rdfs:label>nef from Simian Immunodeficiency Virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 1490008; PMID: 1470917</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002745 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002745">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001446"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002745</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A virus with a mutation in protein C is attenuated in mice and induced protection from challenge with wild type TBE virus</rdfs:comment>
        <rdfs:label>C protein from Tick-borne Encephalitis Virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 206570298; PMID: 11884577</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002746 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002746">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001447"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002746</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE</rdfs:comment>
        <rdfs:label>E1 glycoprotein from VEE Virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 798795; PMID: 7676619</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002747 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002747">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001447"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002747</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE</rdfs:comment>
        <rdfs:label>PE2 from VEE Virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 229558446; PMID: 7676619</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002748 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002748">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001448"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002748</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A virus with a C protein mutation is attenuated in mice and induces significant protection from challenge with wild type West Nile virus</rdfs:comment>
        <rdfs:label>C protein from West Nile virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 158516889; PMID: 20600500</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002749 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002749">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001449"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002749</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002750</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur</rdfs:comment>
        <rdfs:label>E1 from Western equine encephalomyelitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 17148717; PMID: 12641414</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002750 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002750">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002750</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002749"/>
        <rdfs:comment>A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur</rdfs:comment>
        <rdfs:label>obsolete E1 from Western equine encephalomyelitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 17148717; PMID: 12641414</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002751 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002751">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001449"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002751</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002752</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur</rdfs:comment>
        <rdfs:label>E2 gene from Western equine encephalomyelitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 29611992; PMID: 12641414</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002752 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002752">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002752</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002751"/>
        <rdfs:comment>A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur</rdfs:comment>
        <rdfs:label>obsolete E2 from Western equine encephalomyelitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 29611992; PMID: 12641414</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002753 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002753">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001449"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002753</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002754</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur</rdfs:comment>
        <rdfs:label>PE2 from Western equine encephalomyelitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 90811336; PMID: 12641414</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002754 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002754">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002754</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002753"/>
        <rdfs:comment>A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur</rdfs:comment>
        <rdfs:label>obsolete PE2 from Western equine encephalomyelitis virus</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 90811336; PMID: 12641414</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002755 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002755">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001450"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002755</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A cen1 mutant is attenuated in mice and hamsters and induces significant protection from challenge with wild type L. donovani</rdfs:comment>
        <rdfs:label>cen1 from Leishmania donovani</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 15488542; PMID: 19592661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002756 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002756">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002515"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002756</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A Leishmania infantum deletion mutant of HSP70-II gene is attenuated and provides protection against Leishmania infection in the L. major-BALB/c infection model. Also, DeltaHSP70-II is a safe live vaccine as immunodeficient SCID mice, and hamsters, infected with mutant parasites did not develp any sign of pathology</rdfs:comment>
        <rdfs:label>HSP70 II from Leishmania infantum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 5073319; PMID: 21794145</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002757 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002757">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000172"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002757</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A genetically attenuated parasite (GAP) with a mutation in the FabB/FabF gene is attenuated in mice by arresting in the late liver stage. It also conferred complete protection in mice from challenge with wild type Plasmodium</rdfs:comment>
        <rdfs:label>fabB/fabF from Plasmodium falciparum</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3885996; PMID: 21669394</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002758 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002758">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001451"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002758</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Genetically attenuated P36p-deficient Plasmodium berghei sporozoites provide protection against sporozoites challenge in mice</rdfs:comment>
        <rdfs:label>p36p from Plasmodium berghei</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3424772; PMID: 7604034</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002759 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002759">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001452"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002759</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites</rdfs:comment>
        <rdfs:label>py36 from Plasmodium yoelii</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 23479924; PMID: 17517871</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002760 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002760">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001452"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002760</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites</rdfs:comment>
        <rdfs:label>py52 from Plasmodium yoelii</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 15193062; PMID: 17517871</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002761 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002761">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001452"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002761</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>Deletion of UIS3 in Plasmodium yoelii provided attenuation and full protection in mice by Pyuis3(-) sporozoites required at least 2 immunizations against challenges with infectious sporozoites</rdfs:comment>
        <rdfs:label>UIS3 from Plasmodium yoelii</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 3830198; PMID: 17624848</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002762 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002762">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001453"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002762</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A mic2 mutant is attenuated in mice and induces protection from challenge with wild type T. gondii</rdfs:comment>
        <rdfs:label>mic2 from Toxoplasma gondii</rdfs:label>
        <rdfs:seeAlso>NCBI_Protein_ID: 1923217; PMID: 16933991</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002763 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002763">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001453"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002763</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:hasAlternativeId>VO:0002764</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii</rdfs:comment>
        <rdfs:label>OMPDC from Toxoplasma gondii</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 7899615; PMID: 20605980</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002764 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002764">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002764</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002763"/>
        <rdfs:comment>An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii</rdfs:comment>
        <rdfs:label>obsolete OMPDC from Toxoplasma gondii</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 7899615; PMID: 20605980</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002765 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002765">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000048"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001453"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002765</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0001361"/>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:comment>A UP mutant, in combination with an OMPDC mutation, is attenuated in mice and induces significant protection from wild type T. gondii</rdfs:comment>
        <rdfs:label>UP from Toxoplasma gondii</rdfs:label>
        <rdfs:seeAlso>NCBI_Gene_ID: 900273; PMID: 20605980</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002766 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002766">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002766</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3284</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3284</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>The mutant strain, with deletion of apxIA gene, obtained in this study offered a level of cross-serovar protection against A. pleuropneumoniae infection in mice and pigs (Reference: PMID:16930871).</rdfs:comment>
        <rdfs:label>Actinobacillus pleuropneumoniae apxIA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002767 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002767">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002767</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3112</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3112</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>In the intra-peritoneal mouse model, the virulence of the mutant strain decreased at least 100 fold compared with the parent strain. The mutant was evaluated as a potential vaccine using a vaccination-challenge trial. The death number and lung lesion score in the vaccinated pigs given the serovar 1 challenge were obviously lower than those in the unvaccinated pigs</rdfs:comment>
        <rdfs:label>Actinobacillus pleuropneumoniae ApxIC mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002768 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002768">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002768</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3118</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3118</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Deletion in ureC and apxIIA genes of Actinobacillus pleuropneumoniae serotype 2 prototype provides attenuation and protection in pigs against challenge with the virulent parent strain of A. pleuropneumoniae</rdfs:comment>
        <rdfs:comment>Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application</rdfs:comment>
        <rdfs:label>Actinobacillus pleuropneumoniae ureC and apxIIA double mutant deletion vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002769 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002769">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002769</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3120</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3120</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A precisely defined DeltaapxIICDeltaapxIVA double-deletion mutant of A. pleuropneumoniae was constructed based on HB04C(-) by transconjugation and counterselection. The results demonstrated that the DeltaapxIICDeltaapxIVA double mutant strain was less virulent than HB04C(-). Despite attenuation of virulence, the DeltaapxIICDeltaapxIVA double mutant remains immunogenic and conferred a similar level of protective immunity to pigs against challenge with a lethal dose of a heterologous fully virulent standard serovar 1 strain of A. pleuropneumoniae. (Reference: PubMed: 17767980)</rdfs:comment>
        <rdfs:comment>In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae</rdfs:comment>
        <rdfs:label>Actinobacillus pleuropneumoniae apxIIC and apxIVA double deletion mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002770 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002770">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002770</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0011385"/>
        <rdfs:comment>In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae</rdfs:comment>
        <rdfs:label>obsolete A. pleuropneumoniae HS93C-Ampr</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002771 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002771">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002771</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3119</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3119</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain</rdfs:comment>
        <rdfs:comment>An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain</rdfs:comment>
        <rdfs:label>Actinobacillus pleuropneumoniae apxIIIB and apxIIID double mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002772 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002772">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002772</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002771"/>
        <rdfs:comment>An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain</rdfs:comment>
        <rdfs:label>obsolete Actinobacillus pleuropneumoniae apxIIIB and apxIIID double mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002773 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002773">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002773</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002769"/>
        <rdfs:comment>A precisely defined DeltaapxIICDeltaapxIVA double-deletion mutant of A. pleuropneumoniae was constructed based on HB04C(-) by transconjugation and counterselection. The results demonstrated that the DeltaapxIICDeltaapxIVA double mutant strain was less virulent than HB04C(-). Despite attenuation of virulence, the DeltaapxIICDeltaapxIVA double mutant remains immunogenic and conferred a similar level of protective immunity to pigs against challenge with a lethal dose of a heterologous fully virulent standard serovar 1 strain of A. pleuropneumoniae. (Reference: PubMed: 17767980)</rdfs:comment>
        <rdfs:label>obsolete Actinobacillus pleuropneumoniae apxIIC and apxIVA double deletion mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002774 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002774">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002774</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002768"/>
        <rdfs:comment>Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application</rdfs:comment>
        <rdfs:label>obsolete Actinobacillus pleuropneumoniae ureC and apxIIA double mutant deletion vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002775 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002775">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002775</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3115</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>3115</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An mntA deletion mutant, generated by allelic replacement, in Bacillus anthracis was attenuated and provided protection for guinea pigs against lethal spore dose (60 LD50) of the virulent B. anthracis Vollum strain</rdfs:comment>
        <rdfs:label>Bacillus anthracis mntA deletion mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002776 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002776">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002500"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1639"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002776</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3214</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3214</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1639"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes</rdfs:comment>
        <rdfs:label>Listeria monocytogenes actA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002777 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002777">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002500"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1639"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002777</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3215</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3215</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1639"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A plcB mutant, in combination with an actA mutant, is attenuated in mice and induces significant protection from challenge with wild type L. monocytogenes</rdfs:comment>
        <rdfs:comment>An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes</rdfs:comment>
        <rdfs:label>Listeria monocytogenes actA/plcB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002778 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002778">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002778</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002777"/>
        <rdfs:comment>A plcB mutant, in combination with an actA mutant, is attenuated in mice and induces significant protection from challenge with wild type L. monocytogenes</rdfs:comment>
        <rdfs:label>obsolete Listeria monocytogenes actA/plcB mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002779 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002779">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002501"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1764"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002779</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3212</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3212</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1764"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A M. avium relA mutant is attenuated in calves and goats. This mutant also elicited an immune response in goats that limited colonization by challenge wild type M. avium</rdfs:comment>
        <rdfs:label>Mycobacterium avium relA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002780 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002780">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGG_3000888491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002780</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3203</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/OGG_3000888491"/>
        <obo:VO_0001818>3203</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A drrC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis drrC mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002781 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002781">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGG_3000887603"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002781</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3204</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/OGG_3000887603"/>
        <obo:VO_0001818>3204</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An fadD26 mutant is attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis fadD26 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002782 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002782">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGG_3000888225"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002782</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3205</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/OGG_3000888225"/>
        <obo:VO_0001818>3205</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Deletion of leuD gene was shown to be highly attenuated. Immunocompetent BALB/c mice vaccinated with the DleuD auxotroph were protected as well as BCG in terms of survival following an intravenous or aerosol challenge with virulent M. tuberculosis</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis leuD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002783 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002783">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGG_3000885594"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGG_3000886960"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002783</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3206</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/OGG_3000885594"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/OGG_3000886960"/>
        <obo:VO_0001818>3206</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A lysA mutant, in combination with a secA2 mutation, is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis lysA/secA2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002784 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002784">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002784</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A Mce-2 mutant in Mycobacterium tuberculosis is attenuated and provides protection against challenge for mice</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis mce-2/mce-3 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002785 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002785">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_37124"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0050012"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_37124"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002785</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Chikungunya virus</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0050012"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_37124"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>chikungunya virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002786 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002786">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGG_3000885459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGG_3000885596"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002786</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3208</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/OGG_3000885459"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/OGG_3000885596"/>
        <obo:VO_0001818>3208</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis panCD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002787 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002787">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002787</metadata:prefixIRI>
        <obo:IAO_0000115>RD1 and panCD mutants in Mycobacterium tuberculosis were attenuated and provided protection in CD4-deficient mice against an aerosol challenge with virulent M. tuberculosis</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3281</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>3281</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis RD1/panCD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002788 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002788">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1307"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1307"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002788</metadata:prefixIRI>
        <obo:IAO_0000115>a bacterial vaccine against Streptococcus suis infection</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1307"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus suis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002789 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002789">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1719"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003534"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1719"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002789</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine against infection with Corynebacterium pseudotuberculosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1719"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Corynebacterium pseudotuberculosis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002790 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002790">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002790</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000588"/>
        <rdfs:comment>Study evaluated immunogenicity and protection against Mycobacterium tuberculosis in rhesus monkeys with an attenuated M. tuberculosis with a disrupted phoP gene (SO2) as a single-dose vaccine. SO2 treatment showed reduced average lung bacterial counts (1.0 and 1.2 log respectively, compared with 0.4 log for BCG) and significant protective effect by reduction in C-reactive protein levels, body weight loss, and decrease of erythrocyte-associated hematologic parameters (MCV, MCH, Hb, Ht) as markers of inflammatory infection, all relative to non-vaccinated controls</rdfs:comment>
        <rdfs:label>obsolete M. tuberculosis phoP mutant SO2</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002791 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002791">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002791</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3209</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>3209</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A proC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis that is equal to the protection induced by the current vaccine BCG</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis proC mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002792 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002792">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6334"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6334"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002792</metadata:prefixIRI>
        <obo:IAO_0000115>A protozoan vaccine against Trichinella spiralis infection</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6334"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trichinella spiralis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002793 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002793">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1936"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1936"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002793</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that prevents or treats atherosclerosis disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.onlinejacc.org/content/64/25/2779</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1936"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>atherosclerosis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002794 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002794">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002794</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000564"/>
        <rdfs:comment>Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Guerin vaccination.</rdfs:comment>
        <rdfs:label>obsolete M. tuberculosis secA2 mutant</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002795 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002795">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGG_3000888751"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002795</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3211</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/OGG_3000888751"/>
        <obo:VO_0001818>3211</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A sigE mutant is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis, more so than the existing vaccine BCG</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis sigE mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002796 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002796">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001039"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OGG_3000887681"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002796</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3210</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001039 rdf:resource="http://purl.obolibrary.org/obo/OGG_3000887681"/>
        <obo:VO_0001818>3210</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A trpD mutant is highly attenuated in mice and induces more protection from challenge with wild type M. tuberculosis than that induced by the current vaccine BCG</rdfs:comment>
        <rdfs:label>Mycobacterium tuberculosis trpD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002797 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002797">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002502"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002797</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3149</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3149</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. aureus</rdfs:comment>
        <rdfs:label>Staphylococcus aureus aroA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002798 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002798">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000948"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1336"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002798</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3148</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3148</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1336"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A vicK mutant is attenuated in mice and induced protection from challenge with wild type S. equi</rdfs:comment>
        <rdfs:label>Streptococcus equi vicK mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002799 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002799">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_644"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002799</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3114</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3114</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_644"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An A. hydrophila aroA mutant is highly attenuated in trout, and a single immunization conferred significant protection from challenge with wild type A. hydrophila</rdfs:comment>
        <rdfs:label>Aeromonas hydrophila aroA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002800 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002800">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002800</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0011386"/>
        <rdfs:comment>The aroA gene was inactivated by inserting a fragment expressing kanamycin resistance within the coding sequence and challenged in fish. The LD50 for unvaccinated fish was 71. In contrast, the LD50 was 1.8 x 104 in fish vaccinated once and 3 x 105 in fish vaccinated twice</rdfs:comment>
        <rdfs:label>obsolete A. salmonicida live-attenuated vaccine encoding AroA</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002801 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002801">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000394"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002801</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3122</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3122</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract</rdfs:comment>
        <rdfs:label>Bordetella bronchiseptica aroA mutant vaccine (strain BBS18)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002802 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002802">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000394"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002802</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3268</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3268</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A trpE mutant, in combination with an aroA mutation, is attenuated in mice and induces significant protection from challenge with wild type B. bronchiseptica</rdfs:comment>
        <rdfs:comment>Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract</rdfs:comment>
        <rdfs:label>Bordetella bronchiseptica aroA/trpE mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002803 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002803">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000394"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002803</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3123</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3123</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 x 105 CFU of RB50, the B. Bronchiseptica parent strain</rdfs:comment>
        <rdfs:label>Bordetella bronchiseptica bscN and cyaA double mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002804 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002804">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002804</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002803"/>
        <rdfs:comment>A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 x 105 CFU of RB50, the B. Bronchiseptica parent strain.</rdfs:comment>
        <rdfs:label>obsolete Bordetella bronchiseptica bscN and cyaA double mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002805 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002805">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000394"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002805</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3124</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3124</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_518"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A dnt mutant in Bordetella bronchiseptica was attenuated and provides protection in guinea pigs against intranasal challenge with strain L3</rdfs:comment>
        <rdfs:label>Bordetella bronchiseptica dnt mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002806 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002806">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002806</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002802"/>
        <rdfs:comment>A trpE mutant, in combination with an aroA mutation, is attenuated in mice and induces significant protection from challenge with wild type B. bronchiseptica</rdfs:comment>
        <rdfs:label>obsolete Bordetella bronchiseptica aroA/trpE mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002807 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002807">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002807</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3134</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>3134</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in mice and induces significant protection from challenge with wild type B. pertussis</rdfs:comment>
        <rdfs:label>Bordetella pertussis aroA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002808 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002808">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002808</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3176</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>3176</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A live attenuated B. pertussis vaccine strain BPZE1, developed by deleting dnt gene, protects mice upon a single intranasal administration</rdfs:comment>
        <rdfs:label>Bordetella pertussis dnt mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002809 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002809">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000764"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002809</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3267</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
        <obo:VO_0001818>3267</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A flagella-less mutant of Borrelia burgdorferi (HB19Fla-) was attenuated in immunodeficient SCID mice. Mice were challenged 28 days later with virulent strain Sh. 2 and were protected from challenge</rdfs:comment>
        <rdfs:label>Borrelia burgdorferi fla mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002810 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002810">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002810</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=299</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>299</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A asp24 mutation in Brucella abortus is attenuated and provides significant protection in mice</rdfs:comment>
        <rdfs:comment>A virB2 mutant is attenuated in Brucella melitensis and provides protection in mice</rdfs:comment>
        <rdfs:comment>Mutants manB and manA were attenuated in Brucella melitensis and provided protection against challenge in mice&apos;s livers</rdfs:comment>
        <rdfs:comment>Unmarked rough B. abortus and B. melitensis deletion mutants of manBA (including manA and manB) were attenuated. These mutants provided protection against virulent Brucella challenge in mice</rdfs:comment>
        <rdfs:label>Brucella abortus and Brucella melitensis mutants with unmarked deletion of asp24, virB2, or manBA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002811 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002811">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9351"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9351"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002811</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that prevents or treats diabetes.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/12956615</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9351"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>diabetes vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002812 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002812">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002812</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3260</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>3260</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Brucella DeltaexsA mutant showed decreased survival in mice compared to the survival of parental strain S2308. This demonstrated that ExsA is critical for full bacterial virulence. The B. abortus exsA deletion mutant was used as a live vaccine candidate. Challenge experiments revealed that the exsA mutant strain induced superior protective immunity in BALB/c mice compared to the protective immunity induced by strain S19 or RB51</rdfs:comment>
        <rdfs:label>Brucella abortus exsA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002813 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002813">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002813</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that prevents or treats a non-infectious disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/12831367</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
        <rdfs:comment>There are mainly five types of non-infectious diseases, which are diabetes, allergies, cardiovascular diseases, cancer and genetic diseases. URL: http://www.ychlpyss.edu.hk/~bio/share/0405/f6homework/Non-infectious%20disease/noninfectiousdisease(ths).htm</rdfs:comment>
        <rdfs:label>obsolete non-infectious disease vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002814 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002814">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002814</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002810"/>
        <rdfs:comment>Mutants manB and manA were attenuated in Brucella melitensis and provided protection against challenge in mice&apos;s livers</rdfs:comment>
        <rdfs:comment>Unmarked rough B. abortus and B. melitensis deletion mutants of manBA (including manA and manB) were attenuated. These mutants provided protection against virulent Brucella challenge in mice</rdfs:comment>
        <rdfs:label>obsolete B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002815 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002815">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002815</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0004277"/>
        <rdfs:comment>A mucR mutant has a significantly reduced degree of colonization in mice and protects against wild type B. melitensis 16M</rdfs:comment>
        <rdfs:label>obsolete B. melitensis mucR mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002816 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002816">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002816</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0004001"/>
        <rdfs:comment>A omp25 mutant is attenuated and provides protection against challenge in mice</rdfs:comment>
        <rdfs:label>obsolete B. melitensis omp25 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002817 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002817">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002817</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0004002"/>
        <rdfs:comment>A omp31 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice</rdfs:comment>
        <rdfs:label>obsolete B. melitensis omp31 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002818 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002818">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002818</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3264</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>3264</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A pgk mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus</rdfs:comment>
        <rdfs:label>Brucella abortus pgk mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002819 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002819">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002819</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3263</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>3263</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A pgm mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus</rdfs:comment>
        <rdfs:label>Brucella abortus pgm mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002820 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002820">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001135"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002820</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis WR201 (16MΔpurEK)</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A purE/purK mutant of B. melitensis 16M was attenuated in mice when given intraperitoneally. Nine weeks after immunization, mice were protected from challenge with wild type B. melitensis</rdfs:comment>
        <rdfs:comment>Mice infected with delta purE201 developed only five to eight times normal spleen weight at 1 week p.i. and produced no interleukin-6 in their serum, which is much lower than the mice infected with the parental strain (16M)</rdfs:comment>
        <rdfs:label>Brucella melitensis WR201 (16MΔpurEK) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002821 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002821">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002821</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002820"/>
        <rdfs:comment>A purE/purK mutant of B. melitensis 16M was attenuated in mice when given intraperitoneally. Nine weeks after immunization, mice were protected from challenge with wild type B. melitensis</rdfs:comment>
        <rdfs:label>obsolete B. melitensis WR201 (16M-delta-purEK)</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002822 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002822">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002822</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002810"/>
        <rdfs:comment>A virB2 mutant is attenuated in Brucella melitensis and provides protection in mice</rdfs:comment>
        <rdfs:label>obsolete B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002823 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002823">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_848"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_848"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002823</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that prevents or treats arthritis.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/12956615</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_848"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>arthritis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002824 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002824">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001134"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002824</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>live attenuated B. abortus with deletion of znuA</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Deletion of gene znuA attenuates Brucella abortus and this live attenuated vaccine was challenged in mice. These mice showed significantly fewer spenic CFU</rdfs:comment>
        <rdfs:label>live attenuated Brucella abortus with deletion of znuA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002825 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002825">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012175"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002825</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3179</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3179</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>The aroC deletion in the resultant mutant, designated A2 Delta aroC, was confirmed by PCR, Southern hybridization and failure of the mutant to grow in a defined medium without aromatic compounds. The constructed unmarked aroC mutant of B. pseudomallei is attenuated in both BALB/c and C57Bl/6 mice and is able to confer significant protection in C57Bl/6 mice.</rdfs:comment>
        <rdfs:label>Burkholderia pseudomallei aroC deletion mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002826 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002826">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012175"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002826</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3272</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3272</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An asd mutant is highly attenuated in mice. This mutant was also able to protect against acute inhalation melioidosis caused by challenge with wild type B. pseudomallei</rdfs:comment>
        <rdfs:label>Burkholderia pseudomallei asd mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002827 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002827">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012175"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002827</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3257</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3257</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Mice that were challenged with a higher dose of mutant 56:65 purM were protected</rdfs:comment>
        <rdfs:label>Burkholderia pseudomallei purM mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002828 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002828">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012175"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002828</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3258</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3258</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Although 30:93a purN -immunized mice were challenged with a 10-fold higher dose of WT E8, mice were strongly protected and showed no signs of clinical illness until the experiment was terminated</rdfs:comment>
        <rdfs:label>Burkholderia pseudomallei purN mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002829 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002829">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001521"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_67780"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002829</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>E. ictaluri crp mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3283</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3283</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_67780"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A crp mutant is attenuated in zebrafish and catfish that were immunized intramuscularly and intracoelomically, respectively. Six weeks after immunization, both zebrafish and catfish were protected from challenge with wild type E. ictaluri</rdfs:comment>
        <rdfs:label>Edwardsiella ictaluri crp mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002830 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002830">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002506"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002830</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3273</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3273</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%</rdfs:comment>
        <rdfs:label>Edwardsiella tarda aroC mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002831 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002831">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002506"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002831</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3275</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3275</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroC and slyA mutant is attenuated in zebra fish. This mutant is also protective against challenge from wild type E. tarda, resulting in a relative percent survival of 80.1%</rdfs:comment>
        <rdfs:comment>An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%</rdfs:comment>
        <rdfs:label>Edwardsiella tarda aroC/slyA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002832 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002832">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002506"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002832</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3274</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3274</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroC and esrC mutant is attenuated in zebra fish. This mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 71.3%</rdfs:comment>
        <rdfs:comment>An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%</rdfs:comment>
        <rdfs:label>Edwardsiella tarda aroC/esrC mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002833 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002833">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002506"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002833</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3253</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3253</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An esrB mutant is highly attenuated in fish (turbot), with an LD50 of 10(8.1)cfu/fish. Vaccination with this mutant elicited significant protection from wild type E. tarda</rdfs:comment>
        <rdfs:label>Edwardsiella tarda esrB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002834 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002834">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002834</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002832"/>
        <rdfs:comment>An aroC and esrC mutant is attenuated in zebra fish. This mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 71.3%</rdfs:comment>
        <rdfs:label>obsolete Edwardsiella tarda aroC/esrC mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002835 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002835">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002835</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002831"/>
        <rdfs:comment>An aroC and slyA mutant is attenuated in zebra fish. This mutant is also protective against challenge from wild type E. tarda, resulting in a relative percent survival of 80.1%</rdfs:comment>
        <rdfs:label>obsolete Edwardsiella tarda aroC/slyA mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002836 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002836">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000962"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9103"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002836</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>Escherichia coli carAB mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3248</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001818>3248</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9103"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A carAB mutant is attenuated in turkeys and induces significant protection from challenge with wild type E. coli</rdfs:comment>
        <rdfs:label>E. coli carAB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002837 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002837">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_417"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005503"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_417"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002837</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that prevents or treats an autoimmune disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/15196997</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_417"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>autoimmune disease vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002838 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002838">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000962"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002838</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>Escherichia coli ler mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3249</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001818>3249</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A ler deletion mutant derived from wild-type EHEC O157:H7 86-24 was constructed by use of suicide vector pCVD442. Following challenge of 7-day-old suckling mice with O157:H7 EDL933, 75.2% born to group B mothers (immunized with F25) sur- vived, as did 83.0% born to group C mothers (immunized with F105). The surviving suckling mice consistently gained body weight. Only 16.8% of sucking mice born to control group mice survived the challenge</rdfs:comment>
        <rdfs:label>E. coli ler mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002839 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002839">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000962"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002839</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>Escherichia coli rfaL mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3279</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001818>3279</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Deletion of waaL results in a strain that stimulates enhanced urothelial cytokine secretion, which is an enhanced innate immune response. Inoculation with the vaccine strain protected mice against challenge with a broad range of clinical uropathogenic E. coli isolates and produced immunity that lasted &gt;= 8 weeks.</rdfs:comment>
        <rdfs:label>E. coli rfaL mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002840 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002840">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002840</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3232</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3232</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>There was a deletion in gene capB of F. tularensis live vaccine strain. LVS capB, while much less virulent than LVS, induces potent protective immunity against lethal LVS i.n. challenge in mice, comparable to that induced by LVS</rdfs:comment>
        <rdfs:label>Francisella tularensis capB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002841 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002841">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002841</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3280</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3280</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A clpB mutant in Francisella tularensis subspecies tularensis strain SCHU S4 was attenuated and provided protection against aerosol challenge in mice</rdfs:comment>
        <rdfs:label>Francisella tularensis clpB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002842 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002842">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002842</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3233</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3233</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A FTL0552 mutant in Francisella tularensis was attenuated and provided partial protection in mice against challenge with a lethal dose of the virulent SchuS4 strain when compared to naive mice</rdfs:comment>
        <rdfs:label>Francisella tularensis FTL0552 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002843 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002843">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002843</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3234</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3234</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An FTT0918 mutant showed significantly reduced virulence in mice. Mice that recovered from infection with the mutant were protected 2 months later from challenge with wild type F. tularensis</rdfs:comment>
        <rdfs:label>Francisella tularensis FTT0918 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002844 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002844">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002844</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3278</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3278</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A galU mutant is attenuated in mice, with only transient weight loss observed. Two months after inoculation, mice were challenge with wild type F. tularensis and were protected, once again only experiencing transient weight loss</rdfs:comment>
        <rdfs:label>Francisella tularensis galU mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002845 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002845">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002845</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3235</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3235</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A guaA mutant is highly attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS</rdfs:comment>
        <rdfs:label>Francisella tularensis guaA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002846 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002846">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002846</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3236</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3236</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A guaB mutant is attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS</rdfs:comment>
        <rdfs:label>Francisella tularensis guaB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002847 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002847">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002847</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3237</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3237</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Intranasal vaccination with KKF235 (F. tularensis subsp. novicida mutant (DeltaiglB) ) protected mice from subsequent homotypic challenge with U112 as well as heterotypic challenge with F. tularensis subsp. holarctica (LVS). Most significantly, oral immunization with KKF235 protected mice from a highly lethal subsp. tularensis (SCHU S4) pulmonary challenge</rdfs:comment>
        <rdfs:label>Francisella tularensis IglB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002848 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002848">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002848</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000307"/>
        <rdfs:comment>An iglC mutant is highly attenuated in mice. Inoculated mice were challenged 30 days later with wild type F. tularensis and were highly protected</rdfs:comment>
        <rdfs:label>obsolete KKF24</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002849 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002849">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002849</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3238</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3238</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A purMCD mutant in Francisela tularensis was attenuated. A low dosage of F. tularensis LVS delta purMCD mutant provided protection against challenge in mice</rdfs:comment>
        <rdfs:comment>A purMCD mutant in Francisella tularensis was attenuated. A low dose of the F. tularensis LVS delta purMCD mutant provided protection against subsequent lethal challenge with the LVS parental strain</rdfs:comment>
        <rdfs:label>Francisella tularensis purMCD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002850 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002850">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002850</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3239</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3239</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Mice, which had been immunized with at least 6.95x103 cfu of F. tularensis U112 purF::Cm, were protected against the subsequent F. tularensis subspecies novicida challenge.</rdfs:comment>
        <rdfs:label>Francisella tularensis purF mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002851 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002851">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002851</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002849"/>
        <rdfs:comment>A purMCD mutant in Francisella tularensis was attenuated. A low dose of the F. tularensis LVS delta purMCD mutant provided protection against subsequent lethal challenge with the LVS parental strain</rdfs:comment>
        <rdfs:label>obsolete Francisella tularensis purMCD mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002852 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002852">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002852</metadata:prefixIRI>
        <obo:IAO_0000115>A Streptococcus  vaccine against Streptococcus pyogenes infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pyogenes vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002853 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002853">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002853</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3240</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3240</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A sodC mutant in Francisella tularensis subspecies holarctica was attenuated and provided protection and cleared the infection against lethal challenge in nearly 50% of the mice infected with the deletion of sodC mutant.</rdfs:comment>
        <rdfs:label>Francisella tularensis sodC mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002854 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002854">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002854</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3241</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3241</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A wbtA mutant in Francisella tularensis was attenuated and provided protection in mice against challenge with an otherwise lethal dose of either F. tularensis LVS or a fully virulent clinical isolate of F. tularensis type B</rdfs:comment>
        <rdfs:label>Francisella tularensis wbtA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002855 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002855">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002855</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3242</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3242</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A wbtI mutant is attenuated in mice. The mutant protected against a low dose challenge with the parental strain, but was less effective against higher doses. However, increasing the immunization dose increased the resistance to higher challenge doses</rdfs:comment>
        <rdfs:label>Francisella tularensis wbtI mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002856 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002856">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001523"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002856</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3213</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3213</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in mice and induced significant protection after two doses from challenge with wild type M. haemolytica</rdfs:comment>
        <rdfs:label>Mannheimia haemolytica aroA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002857 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002857">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000949"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002857</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3202</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3202</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An lpd mutant is highly attenuated in chickens and induces significant protection from challenge with wild type M. gallisepticum</rdfs:comment>
        <rdfs:label>Mycoplasma gallisepticum lpd mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002858 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002858">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002858</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3200</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>3200</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A metH mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:comment>A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:label>Neisseria meningitidis metH/siaD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002859 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002859">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002859</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3201</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>3201</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:comment>An rfaF mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:label>Neisseria meningitidis rfaF/siaD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002860 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002860">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002860</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002858"/>
        <rdfs:comment>A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:label>obsolete Neisseria meningitidis metH/siaD mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002861 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002861">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002861</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002859"/>
        <rdfs:comment>A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis</rdfs:comment>
        <rdfs:label>obsolete Neisseria meningitidis rfaF/siaD mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002862 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002862">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002862</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3199</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>3199</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in calves and induces significant protection from challenge with wild type P. multocida</rdfs:comment>
        <rdfs:label>Pasteurella multocida aroA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002863 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002863">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000671"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002863</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3156</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001818>3156</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. typhi Ty2</rdfs:comment>
        <rdfs:label>Salmonella typhi aroA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002864 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002864">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000671"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002864</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>Aro-deleted S. Typhi</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=249</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001818>249</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain &quot;CVD 908&quot;</rdfs:comment>
        <rdfs:comment>Inactivation of AroD results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain &quot;CVD 908&quot;</rdfs:comment>
        <rdfs:label>Aro-deleted S. Typhi vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002865 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002865">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000671"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002865</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>CVD 908-htrA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=252</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001818>252</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain &quot;CVD 908&quot;</rdfs:comment>
        <rdfs:label>CVD 908-htrA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002866 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002866">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002866</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002864"/>
        <rdfs:comment>Inactivation of AroD results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain &quot;CVD 908&quot;</rdfs:comment>
        <rdfs:label>obsolete Aro-deleted S. Typhi</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002867 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002867">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002867</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3157</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3157</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium asd mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002868 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002868">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002868</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3158</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3158</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:comment>An rfc mutant, in combination with an asd mutation, is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium asd/rfc mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002869 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002869">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002869</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3159</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3159</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An atpA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium atpA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002870 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002870">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002508"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002870</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3160</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3160</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A cbiA mutant, in combination with a cobS mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis</rdfs:comment>
        <rdfs:comment>A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis</rdfs:comment>
        <rdfs:label>Salmonella Gallinarum cbiA/cobS mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002871 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002871">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002509"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002871</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3271</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3271</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective in mice and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis</rdfs:comment>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective, and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis</rdfs:comment>
        <rdfs:label>Salmonella Enteritidis guaBA/clpP mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002872 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002872">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002872</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3161</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3161</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium clpP mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002873 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002873">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002873</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002872"/>
        <rdfs:comment>A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium guaBA/clpP mutant vaccine (merged to VO_0002872)</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002874 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002874">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002874</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002872"/>
        <rdfs:comment>A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine (merged to VO_0002872)</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002875 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002875">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002875</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002870"/>
        <rdfs:comment>A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis</rdfs:comment>
        <rdfs:label>obsolete Salmonella Gallinarum cbiA/cobS mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002876 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002876">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002876</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3162</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3162</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002877 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002877">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002508"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002877</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3163</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3163</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A cpxR mutant, in combination with a lon mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum</rdfs:comment>
        <rdfs:comment>A lon mutant, in combination with a cpxR mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum</rdfs:comment>
        <rdfs:label>Salmonella Gallinarum cpxR/Ion mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002878 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002878">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002878</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3290</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3290</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium cya/crp mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002879 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002879">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002508"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002879</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3164</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3164</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A crp mutant is attenuated in mice and induces significant protection from challenge with wild type S. gallinarum</rdfs:comment>
        <rdfs:label>Salmonella Gallinarum crp mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002880 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002880">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002880</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002878"/>
        <rdfs:comment>A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium cya/crp mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002881 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002881">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002509"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002881</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3165</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3165</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A fliC mutant, in combination with a guaB mutant, is attenuated in mice and chickens and induces significant protection from challenge with wild type S. enterica</rdfs:comment>
        <rdfs:comment>A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica</rdfs:comment>
        <rdfs:comment>JZ: based on comment,VO:0002890 should be &apos;Salmonella enterica fliC/guaB mutant vaccine&apos;.</rdfs:comment>
        <rdfs:label>Salmonella enterica fliC/guaB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002882 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002882">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002882</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3270</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3270</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A guaBA, clpP, and fliD mutant (CVD 1923) is attenuated in mice after oral immunization. This mutant is also protective, with a vaccine efficacy of 80% in mice against wild type challenge from Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002883 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002883">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000671"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002883</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3166</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001818>3166</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A gal E mutant in strain Ty2 was isolated, attenuated, and protected mice against lethal challenge</rdfs:comment>
        <rdfs:label>Salmonella Typhi galE mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002884 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002884">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002884</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002871"/>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective in mice and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis</rdfs:comment>
        <rdfs:label>obsolete Salmonella Enteritidis guaBA/clpP mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002885 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002885">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002885</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3269</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3269</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium guaBA/clpP mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002886 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002886">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002886</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002885"/>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine (merged to VO_0002885)</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002887 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002887">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002887</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002885"/>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium guaBA/clpP mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002888 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002888">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002888</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002885"/>
        <rdfs:comment>A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine (merged to VO_0002885)</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002889 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002889">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002889</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002881"/>
        <rdfs:comment>A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica</rdfs:comment>
        <rdfs:label>obsolete Salmonella enterica fliC/guaB mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002890 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002890">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002890</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002881"/>
        <rdfs:comment>A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica</rdfs:comment>
        <rdfs:label>obsolete Salmonella Enteritidis guaBA/clpP mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002891 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002891">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002891</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002876"/>
        <rdfs:comment>A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002892 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002892">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002892</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3167</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3167</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Oral immunization with the Salmonella hfq deletion mutant efficiently protects mice against subsequent oral challenge with virulent strain of Salmonella Typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium hfq mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002893 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002893">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002893</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3168</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3168</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A htrA mutant in Salmonella typhimurium is attenuated and provides protection in mice against an oral challenge with virulent S. typhimurium SL1344</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium htrA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002894 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002894">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002894</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002877"/>
        <rdfs:comment>A lon mutant, in combination with a cpxR mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum</rdfs:comment>
        <rdfs:label>obsolete Salmonella Gallinarum cpxR/Ion mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002895 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002895">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002895</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>Salmonella Typhimurium IppA/IppB/msbB</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3169</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3169</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An lppA mutant, in combination with an lppB/msbB mutation, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:comment>An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:comment>An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium IppA/IppB/msbB vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002896 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002896">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002896</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002895"/>
        <rdfs:comment>An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium IppA/IppB/msbB</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002897 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002897">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002897</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3170</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3170</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:comment>An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium IppB/msbB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002898 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002898">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002898</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002895"/>
        <rdfs:comment>An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium IppA/IppB/msbB</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002899 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002899">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002899</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002897"/>
        <rdfs:comment>An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium IppB/msbB mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002900 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002900">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002900</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3291</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3291</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>In a pig infection experiment including two oral immunizations with SalmoporcDeltaompD (OmpD, nmpC) and challenge with a multiresistant S. enterica serovar Typhimurium DT104 clinical isolate, we confirmed the protective efficacy of SalmoporcDeltaompD in pigs, showing a significant reduction of both clinical symptoms and colonization of lymph nodes and intestinal tract</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium ompD/nmpC mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002901 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002901">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002508"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002901</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3171</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3171</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A nuoG mutant is attenuated in chickens and induced significant protection from challenge with wild type S. Gallinarum</rdfs:comment>
        <rdfs:label>Salmonella Gallinarum nuoG mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002902 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002902">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002902</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3172</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3172</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An ompR mutant is attenuated in mice after oral challenge. Twenty eight days after immunization, mice were challenged with wild type S. typhimurium and were significantly protected</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium ompR mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002903 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002903">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000671"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002903</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3173</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001818>3173</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Three S. typhi deletion mutants (phoP, rpoS, and rpoS-phoP double mutant) were constructed and characterized with respect to invasiveness, virulence, and protective immune response compared with wild-type Ty2. All S. typhi mutants showed an increase in the specific serum IgG levels and T-cell-mediated immunity, and showed equal protection abilities against a wild-type Ty2 challenge after two rounds of immunization in BALB/c mice</rdfs:comment>
        <rdfs:label>Salmonella Typhi phoP mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002904 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002904">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002904</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3174</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3174</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A poxA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium poxA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002905 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002905">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002508"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002905</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3175</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3175</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum</rdfs:comment>
        <rdfs:label>Salmonella Gallinarum relA/spoT mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002906 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002906">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002906</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002868"/>
        <rdfs:comment>An rfc mutant, in combination with an asd mutation, is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium asd/rfc mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002907 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002907">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002907</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002876"/>
        <rdfs:comment>A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002908 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002908">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002908</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3181</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3181</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Immunizations with Salmonella typhimurium rpoS and rpoS aroA mutants protected susceptible BALB/c mice against subsequent oral challenge with virulent S. typhimurium. When administered orally or intraperitoneally, rpoS derivatives of the mouse-virulent S. typhimurium strains, C52 and SL1344, were highly attenuated and were efficient single-dose live vaccines</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium rpoS mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002909 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002909">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002909</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3182</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3182</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A ruvB mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium ruvB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002910 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002910">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002910</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002905"/>
        <rdfs:comment>A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum</rdfs:comment>
        <rdfs:label>obsolete Salmonella Gallinarum relA/spoT mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002911 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002911">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002911</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3183</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3183</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A surA mutant (BRD1115) is attenuated in BALB/c mice and induces protection from challenge with wild type S. typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium surA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002912 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002912">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002912</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3184</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3184</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A tolA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium tolA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002913 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002913">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002913</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3185</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3185</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A trxA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium trxA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002914">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002914</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3282</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3282</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A wecA mutant (DSM645) is attenuated in C57BL/6J mice through i.p. and oral immunization. This mutant also protects against challenge with S. typhimurium strains TML and SL1344 30 days after immunization</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium wecA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002915 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002915">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002915</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3186</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3186</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90371"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:label>Salmonella Typhimurium znuABC mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002916 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002916">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002916</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002915"/>
        <rdfs:comment>A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium znuABC mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002917 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002917">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002917</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002915"/>
        <rdfs:comment>A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium</rdfs:comment>
        <rdfs:label>obsolete Salmonella Typhimurium znuABC mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002918 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002918">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002918</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002920"/>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>obsolete CVD 1204(pGA1-CS2)</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002919 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002919">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002919</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000676"/>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>obsolete S. dysenteriae 1 strain WRSd1</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002920 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002920">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000680"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002920</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>S. flexneri 2a strain CVD 1203</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=262</obo:IAO_0000119>
        <obo:VO_0001818>262</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>Shigella flexneri 2a strain CVD 1203 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002921 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002921">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002921</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000678"/>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>obsolete S. sonnei strain WRSS1</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002922 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002922">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000680"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002922</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>S. flexneri strain Sfl 124</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>Shigella flexneri strain Sfl 124 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002923 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002923">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000680"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002923</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3151</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3151</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>Shigella flexneri aroD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002924 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002924">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000680"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002924</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3152</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3152</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An envZ mutant (SC433) is greatly decreased in virulence in macaque monkeys, though some mild clinical signs were still recorded. This mutant is also highly protective against a challenge of wild type S. flexneri delivered 1 month after inoculation</rdfs:comment>
        <rdfs:label>Shigella flexneri envZ mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002925 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002925">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_236"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000025"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_236"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002925</metadata:prefixIRI>
        <obo:IAO_0000115>a Brucella vaccine against infection wtih B. ovis</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_236"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella ovis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002926 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002926">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002926</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002920"/>
        <rdfs:comment>An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri</rdfs:comment>
        <rdfs:label>obsolete SC602</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002927 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002927">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000679"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002927</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3153</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3153</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_624"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A virG, senA, senB, and msbB2 mutant (WRSs3) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs3 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>Shigella sonnei virG/senA/senB/msbB2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002928 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002928">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000679"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002928</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3154</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3154</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_624"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>Shigella sonnei virG/senA/senB mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002929 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002929">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002929</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002928"/>
        <rdfs:comment>A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>obsolete Shigella sonnei virG/senA/senB/msbB2 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002930 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002930">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002930</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002928"/>
        <rdfs:comment>A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>obsolete Shigella sonnei virG/senA/senB mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002931 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002931">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002931</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002928"/>
        <rdfs:comment>A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1</rdfs:comment>
        <rdfs:label>obsolete Shigella sonnei virG/senA/senB/msbB2 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002932 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002932">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002932</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000678"/>
        <rdfs:comment>A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei</rdfs:comment>
        <rdfs:label>obsolete Shigella sonnei virG/senA/senB mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002933 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002933">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002933</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000678"/>
        <rdfs:comment>A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei</rdfs:comment>
        <rdfs:label>obsolete Shigella sonnei virG/senA/senB/msbB2 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002934 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002934">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000763"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1498"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002934</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3142</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1498"/>
        <obo:VO_0001818>3142</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A hemA mutant is highly attenuated in mice and rabbits and induces protection from challenge with wild type V. cholerae in rabbits</rdfs:comment>
        <rdfs:label>Vibrio cholerae hemA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002935 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002935">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012186"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002935</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3135</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3135</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in mice, and after 3 doses induces significant protection from challenge with wild type Y. enterocolitica</rdfs:comment>
        <rdfs:label>Yersinia enterocolitica aroA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002936 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002936">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012186"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002936</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3136</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3136</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A htrA mutant in Yersinia enterocolitica was attenuated and provided partial protection against challenge in mice</rdfs:comment>
        <rdfs:label>Yersinia enterocolitica htrA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002937 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002937">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012186"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002937</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3137</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3137</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A ompR mutant in Yersinia enterocolitica was attenuated and provided a partial protection from challenge in mice</rdfs:comment>
        <rdfs:label>Yersinia enterocolitica ompR mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002938 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002938">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012186"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002938</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3138</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3138</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A sodA mutant in Yersinia enterocolitica was highly attenuated and mice immunized with a single oral dose of the mutant strain were protected against a lethal oral-challenge infection with wild-type Y. enterocolitica</rdfs:comment>
        <rdfs:label>Yersinia enterocolitica sodA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002939 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002939">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002939</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3128</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3128</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>Yersinia pestis guaBA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002940 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002940">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002940</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002939"/>
        <rdfs:comment>A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>obsolete Yersinia pestis guaBA mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002941 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002941">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002941</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3129</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3129</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An IpxM mutant is attenuated in mice and guinea pigs. This mutant also conferred modest protection from challenge with wild type Y. pestis in Balb/c mice and significant protection in guinea pigs and outbred mice</rdfs:comment>
        <rdfs:label>Yersinia pestis IpxM mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002942 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002942">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002942</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3130</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3130</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An nlpD mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>Yersinia pestis nlpD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002943 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002943">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002943</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3131</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3131</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A pcm mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>Yersinia pestis pcm mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002944 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002944">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002944</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3132</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3132</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>Yersinia pestis smpB/ssrA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002945 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002945">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002945</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002944"/>
        <rdfs:comment>An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>obsolete Yersinia pestis smpB/ssrA mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002946 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002946">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002946</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3133</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3133</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A yopH mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis</rdfs:comment>
        <rdfs:label>Yersinia pestis yopH mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002947 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002947">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002510"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_633"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002947</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3127</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3127</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_633"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A phoP mutant in Yersinia pseudotuberculosis (Yptb) was attenuated and provided protection against oral challenge with virulent Yptb in mice</rdfs:comment>
        <rdfs:label>Yersinia pseudotuberculosis phoP mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002948 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002948">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001035"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29486"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8022"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002948</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3126</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3126</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29486"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8022"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An aroA mutant is highly attenuated in rainbow trout and induces significant protection from challenge with wild type Y. ruckeri</rdfs:comment>
        <rdfs:label>Yersinia ruckeri aroA mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002949 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002949">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002949</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3266</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>3266</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A thymidine kinase-deficient mutant (B8-D53) showed no detectable thymidine kinase-inducing activity and was attenuated in calves. B8-D53 also induced protection from challenge with wild type BHV-1</rdfs:comment>
        <rdfs:label>Bovine herpesvirus 1 UL23 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002950 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002950">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002950</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3178</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>3178</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A deletion of BHV-1 gE gene in strain A is considered as a live attenuated vaccine. After challenge, vaccinated calves were protected against disease and virus shedding was reduced</rdfs:comment>
        <rdfs:label>Bovine herpesvirus 1 US8 (gE) mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002951 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002951">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001507"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002951</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3265</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>3265</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein G deletion in bovine respiratory syncytial virus(rBRSV) and recombinant rBRSV was attenuated and provided protection against a BRSV challenge infection in calves</rdfs:comment>
        <rdfs:label>Bovine respiratory syncytial virus glycoprotein G mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002952 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002952">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002952</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3254</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3254</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An N269A/Q mutation in the E(rns) protein created an attenuated mutant in swine. This mutant was able to induce effective protection in swine against challenge with wild type CSFV</rdfs:comment>
        <rdfs:label>Classical swine fever virus E(rns) mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002953 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002953">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002953</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3255</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3255</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An N to A amino acid substitution was made in the N594 site of the E1 glycoprotein, resulting in attenuation of the virus in swine. This attenuated virus induced protection against challenge with wild type CSFV</rdfs:comment>
        <rdfs:label>Classical swine fever virus E1 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002954 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002954">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002954</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3256</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3256</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A E2 mutant in Classical swine fever virus is attenuated and provides protection in pigs after oronasal vaccination (not intradermal vaccination) against lethal challenge dose of CSFV strain Eystrup</rdfs:comment>
        <rdfs:label>Classical swine fever virus E2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002955 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002955">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001486"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002955</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3250</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3250</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein E mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice</rdfs:comment>
        <rdfs:label>Equid herpesvirus gE mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002956 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002956">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001486"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002956</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3251</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3251</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein I mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice</rdfs:comment>
        <rdfs:label>Equid herpesvirus gI mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002957 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002957">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001486"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002957</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3252</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3252</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A thymidine kinase-deficient mutant (PR1) is attenuated in mice and induced significant protection from challenge with wild type EHV-1 5 weeks after vaccination. In foals, PR1 also showed attenuation; however, the mutant induced only partial protection from challenge with EHV-1</rdfs:comment>
        <rdfs:label>Equid herpesvirus TK mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002958 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002958">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001487"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10334"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002958</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3247</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3247</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10334"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A thymidine kinase-deficient mutant (C7301dlTK) is attenuated in cats and induced significant protection from wild type FHV-1 4 weeks after vaccination</rdfs:comment>
        <rdfs:label>Feline herpesvirus 1 UL23 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002959 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002959">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001508"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11673"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002959</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3245</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3245</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11673"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Feline immunodeficiency virus (FIV) made defective in the accessory gene ORF-A were previously shown to be greatly attenuated in its ability to replicate in lymphocytes but to grow normally or near normally in other cell types. 3/9 vaccinees (cats) showed no evidence of the challenge virus over a 15-month observation period. In the other vaccinees, the challenge virus was predominant for various periods of time, but pre-existing viral loads and CD4 lymphocyte counts were either unaffected or altered only marginally and transiently</rdfs:comment>
        <rdfs:label>Feline immunodeficiency virus ORF-A mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002960 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002960">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001508"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11673"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002960</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3246</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3246</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11673"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A vif mutant in feline immunodeficiency virus was attenuated and a vif-deleted FIV provirus DNA protected cats against challenge with the homologous FIV-PPR biological isolate.</rdfs:comment>
        <rdfs:label>Feline immunodeficiency virus vif mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002961 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002961">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001504"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11135"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002961</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3243</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3243</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11135"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>Feline infectiour peritonitis virus 3abc mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002962 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002962">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002962</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002961"/>
        <rdfs:comment>A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>obsolete Feline infectiour peritonitis virus 3abc mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002963 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002963">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002963</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002961"/>
        <rdfs:comment>A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>obsolete Feline infectiour peritonitis virus 3abc mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002964 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002964">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001504"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11135"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002964</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3244</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3244</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11135"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>Feline infectious peritonitis virus 7ab mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002965 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002965">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002965</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002964"/>
        <rdfs:comment>A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens</rdfs:comment>
        <rdfs:label>obsolete Feline infectious peritonitis virus 7ab mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002966 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002966">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002966</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3228</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3228</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A UL0 mutant in infectious laryngotracheitis virus (ILTV) was attenuated. Chickens immunized with UL0-negative ILTV were protected from clinical disease after subsequent infection with virulent ILTV</rdfs:comment>
        <rdfs:label>Gallid herpesvirus 1 UL0 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002967 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002967">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002967</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3229</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3229</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A thymidine-kinase mutant is attenuated in chickens and induced protection from challenge with wild type GHV-1</rdfs:comment>
        <rdfs:label>Gallid herpesvirus 1 UL23 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002968 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002968">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002968</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3230</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3230</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A UL47 mutant in avian infectious laryngotracheitis virus is attenuated and provides protection in chicken against subsequent challenge infection with virulent ILTV</rdfs:comment>
        <rdfs:label>Gallid herpesvirus 1 UL47 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002969 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002969">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000644"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002969</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3227</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001818>3227</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Researchers generated a series of woodchuck hepatitis virus (WHV) X mutants. Woodchucks inoculated with X mutants, including those with no serologic evidence of infection, were protected from later challenge with infectious Woodchuck Hepatitis Virus, suggesting previous infection with resulting protective immunity</rdfs:comment>
        <rdfs:label>Hepatitis B virus X protein mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002970 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002970">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000958"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002970</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3222</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3222</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>KOS-gDA3C is attenuated with mutations in gD gene in causing skin lesions at the inoculation and zosteriform sites, yet it is as effective as rKOS-gDA3C in protecting mice against HSV-1 challenge</rdfs:comment>
        <rdfs:label>Herpes simplex virus 1 gD mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002971 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002971">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000958"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002971</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3223</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3223</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A gH mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1</rdfs:comment>
        <rdfs:label>Herpes simplex virus 1 gH mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002972 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002972">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012168"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002972</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3224</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3224</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A live-attenuated HSV-2 ICP0 virus provides significant protection against wild-type HSV-2 (MS strain) challenge in mice</rdfs:comment>
        <rdfs:label>Herpes simplex virus 2 ICP0 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002973 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002973">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000958"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002973</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3225</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3225</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A thymidine kinase-deficient (TK) mutant was found to be attenuated in mice. This mutant induced complete protection from challenge with wild type HSV</rdfs:comment>
        <rdfs:label>Herpes simplex virus 1 TK mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002974 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002974">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000958"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002974</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3226</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3226</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A UL29 mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1</rdfs:comment>
        <rdfs:label>Herpes simplex virus 1 UL29 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002975 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002975">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002975</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0011423"/>
        <rdfs:comment>An HSV-1 gE (Us8) deletion strain, NS-gEnull, was used as a live attenuated vaccine. After HSV-1 challenge, latent virus was recovered by DRG explant cocultures from &lt;10% of vaccinated mice compared with 100% of mock-vaccinated mice</rdfs:comment>
        <rdfs:label>obsolete Herpes simplex virus type 1 DNA vaccine encoding GE</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002976 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002976">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002511"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162145"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002976</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3220</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3220</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162145"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A G mutant is attenuated in African green monkeys and induces protection from challenge with wild type HMPV</rdfs:comment>
        <rdfs:label>human metapneumovirus G protein mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002977 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002977">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002511"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162145"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002977</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3221</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3221</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_162145"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An M2-2 mutant is attenuated in African green monkeys and induced protection from challenge with wild type HMPV</rdfs:comment>
        <rdfs:label>human metapneumovirus M2-2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002978 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002978">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002512"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002978</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3219</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3219</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An M2-2 mutant of human respiratory syncytial virus A2 is attenuated in African green monkeys. When challenged with wild type RSV, two doses provided complete protection against challenge in the lower respiratory tract and a significant reduction of the challenge virus in the upper respiratory tract</rdfs:comment>
        <rdfs:label>Human Respiratory Syncytial Virus M2-2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002979 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002979">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8022"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002979</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3218</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3218</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8022"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A mutation in the non-virion protein of IHNV causes attenuated growth in rainbow trout and is able to provide significant protection from subsequent challenge with wild type IHNV</rdfs:comment>
        <rdfs:label>Infectious Hematopoietic Necrosis Virus NV mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002980 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002980">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002980</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1016</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1016</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Mutant influenza virus that lacks the transmembrane and cytoplasmic tail domains of M2 (M2 knockout [M2KO]) from Influenza A virus (A/Puerto Rico/8/34(H1N1)) is attenuated in both cell culture and mice. Mice intranasally vaccinated with M2KO virus developed protective immune responses and survived a lethal challenge with the wild-type virus, suggesting that the M2KO virus has potential as a live attenuated vaccine</rdfs:comment>
        <rdfs:label>influenza virus CTA1-3M2e-DD protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002981 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002981">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002981</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3217</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3217</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Intranasal inoculation of mice, pigs, horses, and macaques with NS1-modified influenza virus strains induced robust humoral and cellular immune responses, and generated immune protection against challenge with wild-type virus</rdfs:comment>
        <rdfs:label>influenza virus NS1 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002982 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002982">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001511"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002982</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3194</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3194</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A mutation in the GP5 protein attenuates HP-PRRSV in piglets. This mutant (HuN4-F112) induces protection against challenge with wild type HP-PRRSV</rdfs:comment>
        <rdfs:label>Porcine respiratory and reproductive syndrome virus GP5 protein mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002983 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002983">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002983</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3189</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3189</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV</rdfs:comment>
        <rdfs:comment>A glycoprotein E mutant, in combination with UL23 and glycoprotein G mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV</rdfs:comment>
        <rdfs:comment>A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV</rdfs:comment>
        <rdfs:label>Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002984 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002984">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002984</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002983"/>
        <rdfs:comment>A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV</rdfs:comment>
        <rdfs:label>obsolete Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002985 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002985">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002985</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3190</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3190</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein M, gM, deletion in pseudorabies virus was attenuated and induced protection in piglets against intranasal challenge with 108 p.f.u. of the highly virulent PrV strain NIA-3</rdfs:comment>
        <rdfs:label>Psuedorabies virus glycoprotein M mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002986 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002986">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002986</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3191</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3191</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky&apos;s disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3</rdfs:comment>
        <rdfs:label>Pseudorabies virus gp50/gp63 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002987 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002987">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002987</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002986"/>
        <rdfs:comment>A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky&apos;s disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3</rdfs:comment>
        <rdfs:label>obsolete Pseudorabies virus gp50/gp63 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002988 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002988">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002988</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002983"/>
        <rdfs:comment>A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV</rdfs:comment>
        <rdfs:label>obsolete Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002989 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002989">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002989</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3192</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3192</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A UL50 mutant is attenuated in pseudorabies virus and induces significant protection in pigs from challenge with the highly virulent NIA-3 strain of PrV</rdfs:comment>
        <rdfs:label>Pseudorabies virus UL50 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002990 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002990">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002990</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3193</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3193</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Researchers intranasally inoculated pigs, the natural host of this virus, with mutant PRV strains in which the genes encoding the protein kinase (US3) proteins were inactivated. After challenge infection with the virulent PRV strain NIA-3, no virus was excreted by wt PRV- and PK- mutant-immunized animals, indicating complete protective immunity</rdfs:comment>
        <rdfs:label>Pseudorabies virus US3 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002991 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002991">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002991</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3187</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>3187</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A glycoprotein G mutant in rabies virus is attenuated. After a one-dose intramuscular vaccination, the ERAg3m virus protected 100% of mice and hamsters from lethal challenge. In co-infections, using a lethal dose of street rabies virus mixed with ERAg3m, 100% of hamsters and 90% of mice survived and were protected against subsequent infection</rdfs:comment>
        <rdfs:label>Rabies virus glycoprotein G mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002992 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002992">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002992</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3188</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>3188</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A P gene mutant is attenuated in mice and induces significant protection from challenge with wild type Rabies virus</rdfs:comment>
        <rdfs:label>Rabies virus P protein mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002993 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002993">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002993</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3155</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3155</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An E mutant is attenuated in hamsters and induces significant protection from challenge with wild type SARS</rdfs:comment>
        <rdfs:label>SARS-CoV E gene mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002994 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002994">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000751"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002994</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3150</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3150</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A SIV nef mutant is attenuated in rhesus monkeys and induces protection from challenge with wild type SIV</rdfs:comment>
        <rdfs:label>Simian Immunodeficiency Virus nef mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002995 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002995">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012190"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0050175"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002995</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0050175"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A virus with a mutation in protein C is attenuated in mice and induced protection from challenge with wild type TBE virus</rdfs:comment>
        <rdfs:label>ick-borne Encephalitis Virus C protein mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002996 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002996">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002996</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3143</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3143</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE</rdfs:comment>
        <rdfs:label>VEE Virus PE2/E1 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002997 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002997">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002997</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0002996"/>
        <rdfs:comment>A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE</rdfs:comment>
        <rdfs:label>obsolete VEE Virus PE2/E1 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002998 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002998">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000752"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002998</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3141</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3141</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A virus with a C protein mutation is attenuated in mice and induces significant protection from challenge with wild type West Nile virus</rdfs:comment>
        <rdfs:label>West Nile virus C protein mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002999 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0002999">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0002999</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <rdfs:comment>A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur</rdfs:comment>
        <rdfs:label>obsolete WEEV DNA Vaccine encoding 6K-E1 Protein</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012188"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003000</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3139</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3139</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur</rdfs:comment>
        <rdfs:label>Western equine encephalomyelitis virus PE2/E1 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003001">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003001</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0003002"/>
        <rdfs:comment>A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur</rdfs:comment>
        <rdfs:label>obsolete WEEV Subunit E2 Protein Vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012188"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003002</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3140</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3140</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur</rdfs:comment>
        <rdfs:label>Western equine encephalomyelitis virus PE2/E2 mutant virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012188"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003003</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur</rdfs:comment>
        <rdfs:label>Western equine encephalomyelitis virus PE2/E1 or E2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003004">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003004</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0003003"/>
        <rdfs:comment>A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur</rdfs:comment>
        <rdfs:label>obsolete Western equine encephalomyelitis virus PE2/E2 mutant virus</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003005</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3216</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3216</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A cen1 mutant is attenuated in mice and hamsters and induces significant protection from challenge with wild type L. donovani</rdfs:comment>
        <rdfs:label>Leishmania donovani cen1 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012159"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003006</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3277</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3277</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A Leishmania infantum deletion mutant of HSP70-II gene is attenuated and provides protection against Leishmania infection in the L. major-BALB/c infection model. Also, DeltaHSP70-II is a safe live vaccine as immunodeficient SCID mice, and hamsters, infected with mutant parasites did not develp any sign of pathology</rdfs:comment>
        <rdfs:label>Leishmania infantum HSP70 II mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003007</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3195</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>3195</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A genetically attenuated parasite (GAP) with a mutation in the FabB/FabF gene is attenuated in mice by arresting in the late liver stage. It also conferred complete protection in mice from challenge with wild type Plasmodium</rdfs:comment>
        <rdfs:label>Plasmodium FabB/FabF mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003008">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002513"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003008</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>P. berghei p36p mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3196</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>3196</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Genetically attenuated P36p-deficient Plasmodium berghei sporozoites provide protection against sporozoites challenge in mice</rdfs:comment>
        <rdfs:label>Plasmodium berghei p36p mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002514"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003009</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>P. yoelii p36/p52 mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3197</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>3197</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites</rdfs:comment>
        <rdfs:label>Plasmodium yoelii p36/p52 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003010">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003010</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0003009"/>
        <rdfs:comment>A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites</rdfs:comment>
        <rdfs:label>obsolete P. yoelii p36/p52 mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002514"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003011</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>P. yoelii UIS3 mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3198</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>3198</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Deletion of UIS3 in Plasmodium yoelii provided attenuation and full protection in mice by Pyuis3(-) sporozoites required at least 2 immunizations against challenges with infectious sporozoites</rdfs:comment>
        <rdfs:label>Plasmodium yoelii UIS3 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003012">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003012</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3144</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3144</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A mic2 mutant is attenuated in mice and induces protection from challenge with wild type T. gondii</rdfs:comment>
        <rdfs:label>Toxoplasma gondii mic2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003013</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3145</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3145</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii</rdfs:comment>
        <rdfs:label>Toxoplasma gondii OMPDC mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003014</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>A UP mutant, in combination with an OMPDC mutation, is attenuated in mice and induces significant protection from wild type T. gondii</rdfs:comment>
        <rdfs:comment>An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii</rdfs:comment>
        <rdfs:label>Toxoplasma gondii OMPDC/UP mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003015">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003015</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0003014"/>
        <rdfs:comment>A UP mutant, in combination with an OMPDC mutation, is attenuated in mice and induces significant protection from wild type T. gondii</rdfs:comment>
        <rdfs:label>obsolete Toxoplasma gondii OMPDC/UP mutant vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003016</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that located in the stomach, so that the material is taken into body through stomach directly. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intragastric route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003016"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003017</metadata:prefixIRI>
        <obo:IAO_0000115>An intragastric route that has a vaccine injection site located in stomach.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intragastric injection route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003016"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003018</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0003016"/>
        <obo:IAO_0000115>vaccination that occurs in the intagastric route.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>intragastric vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003019</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:IAO_0000115>vaccination process that occurs in intradermal route.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>intradermal vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000341"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003020</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000341"/>
        <obo:IAO_0000115>vaccination process that occurs in intranasal route</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>intranasal vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003021">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000886"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003021</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000886"/>
        <obo:IAO_0000115>vaccination process that occurs in oral route.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>oral vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003022</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:IAO_0000115>vaccination process that occurs in the subcutaneous route</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>subcutaneous vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003023 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003023">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000652"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003023</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000652"/>
        <obo:IAO_0000115>A vaccine prepration process that mixes vaccine lyophilized powder and diluent liquid. The process forms a vaccine that can be used for administration. This term can also be considered as a child term of OBI term &apos;material combination&apos;. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>WEB: http://www.thehaiticonnection.org/medical/reconstitution.pdf</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:comment>A vaccine may include vaccine powder and solvent. When the two mix, we get a vaccine solution, which can be used to inject. Examples:
http://www.medicines.org.uk/guides/acwy%20vax/Vaccinations%20%28all%29/
http://www.medicines.org.uk/guides/menitorix/Vaccinations%20%28all%29/ 
http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ </rdfs:comment>
        <rdfs:comment>Use only the specific diluent provided by the manufacturer for each type of vaccine to ensure adequate potency and safety of the resulting mixture.</rdfs:comment>
        <rdfs:label>vaccine reconstitution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003024">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000228"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003024</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine powder that is freeze-dried and lyophilized. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>lyophilized vaccine powder</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003025 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003025">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000415"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003025</metadata:prefixIRI>
        <obo:IAO_0000115>a role inheres in the vaccine component when it is added into vaccine&apos;s formulation, it tends to stabilizes an emulsion by increasing its kinetic stablity.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine emulsifier role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000415"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003026</metadata:prefixIRI>
        <obo:IAO_0000115>a role inheres in vaccine component when added into vaccine&apos;s formulation, it tends to inhibit the reaction between two or more other vaccine substances in the final vaccine formulation; it also helps to protect the vaccine from adverse conditions such as the freeze-drying process or heat.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine stabilizer role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003038"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003028"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003027</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003028"/>
        <obo:IAO_0000115>a protein vaccine stablizer that is specifically human serum albumin.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>human serum albumin vaccine additive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003028">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000516"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003028</metadata:prefixIRI>
        <obo:IAO_0000115>the serum albumin that is part of human</obo:IAO_0000115>
        <obo:IAO_0000116>it is subclass of &apos;serum albumin (PR:000003918)&apos;</obo:IAO_0000116>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>human serum albumin</rdfs:label>
        <rdfs:seeAlso>UniProtKB:P02768</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003030"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003029</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003030"/>
        <obo:IAO_0000115>a vaccine stabilizer that is gelatin.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0003026"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>gelatin vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003030">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003030</metadata:prefixIRI>
        <obo:IAO_0000115>Gelatin is a mixture of peptides and proteins produced by partial hydrolysis of collagen extracted from the skin, boiled crushed bones, connective tissues, organs and some intestines of animals such as domesticated cattle, chicken, and pigs.(wikipedia)</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>gelatin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003031">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000286"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003031</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine-induced gene response that represents a vaccine adverse event response associated with a host susceptibility gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>host susceptibility gene response to vaccine adverse event</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>susceptibility gene response to vaccine adverse event</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003032">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000286"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003032</metadata:prefixIRI>
        <obo:IAO_0000118>host immune factor-induced control of intracellular replication of live attenuated vaccine</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>immune factor-induced control of intracellular replication of live attenuated vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003038"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003033</metadata:prefixIRI>
        <obo:IAO_0000115>a protein vaccine stablizer that is specifically bovine serum albumin. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>bovine serum albumin vaccine additive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000853"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003034</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine stabilizer that is specifically made by a sugar.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>sugar vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003035">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000853"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003035</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine stabilizer that is generated based on amino acids. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>amino acid vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003034"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003036</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine stabilizer that is specifically made by a sucrose. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>sucrose vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003037 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003037">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003034"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003037</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine stabilizer that is specifically made by a lactose.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>lactose vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003038">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000853"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003038</metadata:prefixIRI>
        <obo:IAO_0000115>a vaccine stabilizer that is a protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>protein vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003039 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003039">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000929"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003039</metadata:prefixIRI>
        <obo:IAO_0000115>a polysorbate 20 vaccine stabilizer that is Alkest TW20.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Alkest TW 20 vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000929"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003040</metadata:prefixIRI>
        <obo:IAO_0000115>a polysorbate 20 vaccine stabilizer that is Tween 20.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Tween 20 vaccine stabilizer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003041">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000704"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_7507"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000704"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_7507"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003041</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_7507"/>
        <obo:IAO_0000115>an antibiotics vaccine residual that has the antibiotics of neomycin. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>neomycin residual</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003042">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000919"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000919"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003042</metadata:prefixIRI>
        <obo:IAO_0000115>the vaccine antiegn that induces protective immune response. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>protective vaccine antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003043">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11034"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11034"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003043</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine against infection of an Sindbis virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11034"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Sindbis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003044">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052303"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052303"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003044</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine against infection of a Lymphocytic choriomeningitis virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Lymphocytic choriomeningitis mammarenavirus vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052303"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lymphocytic choriomeningitis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003045">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003045</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete RB51 induced protection against B.suis</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003046">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003047"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003046</metadata:prefixIRI>
        <obo:IAO_0000115>A protozoan vaccine against Schistosoma mansoni</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Schistosoma mansoni vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003047">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6181"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6181"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003047</metadata:prefixIRI>
        <obo:IAO_0000115>A protozoan vaccine against Schistosoma infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6181"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Schistosoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003048 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003048">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003048</metadata:prefixIRI>
        <obo:IAO_0000115>when the vaccination of a significant portion of a population (or herd), in contagious diseases that are transmitted from individual to individual, chains of infection are likely to be disrupted, so the large numbers of a population are immue or less susceptible to the disease. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>http://en.wikipedia.org/wiki/Herd_immunity</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced herd immunity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003049">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000179"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003050"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000179"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003050"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003049</metadata:prefixIRI>
        <obo:IAO_0000115>The conjugate protein is a part of a conjugate vaccine and acts as a carrier protein that is covalently attached to a vaccine antigen with poor antigenicity (e.g., a polysaccharide). A conjugate protein is able to induce T-cell-dependent immune responses and stimulate the production of immune memory.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0003050"/>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine conjugate protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000617"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003050</metadata:prefixIRI>
        <obo:IAO_0000115>A role inheres in a material eneitity that union itself chemically with a relative weak vaccine antigen to form a new whole that can create an effective miinuogen. The </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>vaccine conjugate role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003051</metadata:prefixIRI>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:comment>epicutaneous (application onto the skin)</rdfs:comment>
        <rdfs:label>percutaneous route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003052 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003052">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003051"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003052</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0003051"/>
        <obo:IAO_0000115>Administration of a drug by the way of absorption through the skin, usually for systemic action. The route allows sustained therapeutic plasma drug levels and avoids first pass effect. Simplicity of administration tends to result in high patient compliance.|YL</obo:IAO_0000115>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>percutaneous vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003053 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003053">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003053</metadata:prefixIRI>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intravesical route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000002"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003053"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003054</metadata:prefixIRI>
        <obo:BFO_0000066 rdf:resource="http://purl.obolibrary.org/obo/VO_0003053"/>
        <obo:IAO_0000115>The injection of a given substance directly into the bladder via a urethral catheter instead of being injected under the skin.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>intravesical vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003055">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11002"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11002"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003055</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine against infection of an infectious pancreatic necrosis virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11002"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Infectious pancreatic necrosis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003056 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003056">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003056</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine against infection of a viral haemorrhagic septicaemia virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/688"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0001224"/>
        <rdfs:label>obsolete viral haemorrhagic septicaemia virus vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003057 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003057">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003057</metadata:prefixIRI>
        <obo:IAO_0000115>An vaccine-induced host response that shows augmented protection and cellular immunity after a host protein is used as adjuvant. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete augmented protection and cellular immunity using host protein as adjuvant</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003058 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003058">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1781"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000592"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1781"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003058</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Mycobacterium marinum.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1781"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium marinum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003059 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003059">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12475"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12475"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003059</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Hepatitis D virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12475"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis D virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003060">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10244"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003539"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_3292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10244"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003060</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Monkeypox virus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3292"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10244"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Monkeypox virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003061">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_54315"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003546"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_54315"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003061</metadata:prefixIRI>
        <obo:IAO_0000115>viral vaccine that is used to protect against Bovine viral diarrhea virus 2 infection</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_54315"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine viral diarrhea virus 2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003062">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10366"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000727"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10366"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003062</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Murine Cytomegalovirus (or called murid herpesvirus 1).</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>murine cytomegalovirus vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10366"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Murid herpesvirus 1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003063 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003063">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003063</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete RB51 induced protection against B.abortus</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003064">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003064</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete RB51 induced protection against B.canis</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003065 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003065">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003065</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label>obsolete RB51 induced protection against B.Melitensis</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003066">
        <owl:equivalentClass>
            <owl:Class>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000053"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015372"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000714"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010293"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010295"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010444"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003347"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003360"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003362"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003364"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000531"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000696"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015372"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003066</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Omar Tibi</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5576</obo:IAO_0000119>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1601403</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm431374.htm</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM431447.pdf</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003347"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003360"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003362"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003364"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/VO_0000913"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5576</obo:VO_0001818>
        <obo:VO_0003099>BEXSERO</obo:VO_0003099>
        <obo:VO_0003160>Active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B in individuals 10 through 25 years of age.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM431447.pdf</obo:VO_0003161>
        <obo:VO_0003162>BL 125546</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bexsero vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003067 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003067">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000556"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004673"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
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    <!-- http://purl.obolibrary.org/obo/VO_0003068 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003070 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003071 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003072 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003073 -->

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- Cervical, vulvar, vaginal, and anal cancer caused by Human Papillomavirus (HPV) types 16, 18, 31, 33, 45, 52, and 58. (1.1)
Genital warts (condyloma acuminata) caused by HPV types 6 and 11. (1.1)

And the following precancerous or dysplastic lesions caused by HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58:
- Cervical intraepithelial neoplasia (CIN) grade 2/3 and cervical adenocarcinoma in situ (AIS). (1.1)
- Cervical intraepithelial neoplasia (CIN) grade 1. (1.1)
- Vulvar intraepithelial neoplasia (VIN) grade 2 and grade 3. (1.1)
- Vaginal intraepithelial neoplasia (VaIN) grade 2 and grade 3. (1.1)
- Anal intraepithelial neoplasia (AIN) grades 1, 2, and 3. (1.1)

GARDASIL 9 is indicated in boys and men 9 through 45 years of age for the prevention of the following diseases:
- Anal cancer caused by HPV types 16, 18, 31, 33, 45, 52, and 58. (1.2)
- Genital warts (condyloma acuminata) caused by HPV types 6 and 11. (1.2)

And the following precancerous or dysplastic lesions caused by HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58:
- Anal intraepithelial neoplasia (AIN) grades 1, 2, and 3. (1.2)</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM426457.pdf</obo:VO_0003161>
        <obo:VO_0003162>125508</obo:VO_0003162>
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        <rdfs:label>obsolete RB51 induced protection against B. ovis</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003080 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Omar Tibi</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5578</obo:IAO_0000119>
        <obo:IAO_0000119>http://www.pfizer.ca/sites/g/files/g10028126/f/201604/Nimenrix_PM_184020_23Mar2016_E.pdf</obo:IAO_0000119>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5578</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
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        <rdfs:label>Nimenrix vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003081 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003081</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5577</obo:IAO_0000119>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1593136</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm421020.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5577</obo:VO_0001818>
        <obo:VO_0003099>TRUMENBA</obo:VO_0003099>
        <obo:VO_0003160>Indicated for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. Trumenba is approved for use in individuals 10 through 25 years of age.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM421139.pdf</obo:VO_0003161>
        <obo:VO_0003162>BL 125549</obo:VO_0003162>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trumenba vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003082 -->

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        <obo:IAO_0000119>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM506235.pdf</obo:IAO_0000119>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Omar Tibi</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5553</obo:IAO_0000119>
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        <obo:VO_0003160>Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted is a vaccine indicated for active immunization for the prevention of disease caused by the influenza A virus H5N1 subtype contained in the vaccine. Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted is approved for use in persons (6 months and older) at increased risk of exposure to the influenza A virus H5N1 subtype contained in the vaccine.</obo:VO_0003160>
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    <!-- http://purl.obolibrary.org/obo/VO_0003084 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003086 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003088</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Omar Tibi</obo:IAO_0000117>
        <obo:IAO_0000118>Boostrix-Polio</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5550</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5572</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5580</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5584</obo:IAO_0000119>
        <obo:IAO_0000119>https://ca.gsk.com/media/589683/boostrix-polio.pdf</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_7507"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/VO_0000917"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5550</obo:VO_0001818>
        <obo:VO_0001818>5572</obo:VO_0001818>
        <obo:VO_0001818>5580</obo:VO_0001818>
        <obo:VO_0001818>5584</obo:VO_0001818>
        <obo:VO_0003099>Boostrix-Polio</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Boostrix-Polio vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003090 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003090</metadata:prefixIRI>
        <obo:IAO_0000115>This vaccine is given to provide protection against diphtheria, tetanus, and pertussis in children between 6 weeks and 7 years old.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Tri-Immunol</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.drugs.com/mmx/tri-immunol.html</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.hendricks.org/HealthLibrary/default.aspx?sid=1&amp;pTitle=%2CDrug&amp;ContentTypeID=26&amp;ContentID=215&amp;alpha=T&amp;AdditionalTitle=Tri-Immunol</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>discontinued now</rdfs:comment>
        <rdfs:label>Tri-Immunol vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003091 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003091</metadata:prefixIRI>
        <obo:IAO_0000115>Influenza virus vaccine is used to prevent infection caused by influenza virus types A and B.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Fluogen</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.drugs.com/mtm/fluogen-injectable.html</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluogen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003092 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003092</metadata:prefixIRI>
        <obo:IAO_0000115>monovalent vaccine agianst poliomyelitis for infants 6-12 weeks of age, all immunized children up to 18 years of age, and high risk adults.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.rxlist.com/orimune-drug.htm</obo:IAO_0000119>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Orimune vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003093 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003093</metadata:prefixIRI>
        <obo:IAO_0000115>A malaria vaccine that consists of hepatitis B surface antigen virus-like particles, incorporating a portion of the Plasmodium falciparum-derived circumsporozoite protein and a liposome-based adjuvant.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum RTS,S/AS01</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:20078211</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5945</obo:IAO_0000119>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/RTS,S</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829262/</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5945</obo:VO_0001818>
        <obo:VO_0003099>Mosquirix</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>In July 2015, RTS,S/AS01 was approved by the European Medicines Agency for immunization of children aged 6 weeks to 17 months against malaria under Article 58,12.</rdfs:comment>
        <rdfs:label>Plasmodium falciparum RTS,S/AS01 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003094 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003095 -->

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        <obo:IAO_0000115>Revaxis is a Diphtheria, Tetanus and Poliomyelitis (inactivated) vaccine manufactured by Sanofi Pasteur. This vaccine helps boost protection against diphtheria, tetanus and poliomyelitis (polio).</obo:IAO_0000115>
        <obo:IAO_0000118>3-in-1 diphtheria, polio and tetanus vaccine (Revaxis)</obo:IAO_0000118>
        <obo:IAO_0000119>http://www.netdoctor.co.uk/medicines/infections/a8594/revaxis-diphtheria-polio-and-tetanus-vaccine/</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.medicines.org.uk/emc/files/pil.5581.pdf</obo:IAO_0000119>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166496/</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0003096 -->

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        <obo:IAO_0000115>a Diphthpheria-Tetanus Absorbed vaccine for children 7 years of age and adults.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003097 -->

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        <obo:IAO_0000115>A rotavirus vaccine against severe diarrheal disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://web.stanford.edu/~siegelr/ShadmanRotashieldPaper.pdf</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0003098 -->

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        <obo:IAO_0000115>A more attenuated measles vaccine that targets measles virus strain Moraten.</obo:IAO_0000115>
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        <obo:IAO_0000115>An active immunization against cholera, indicated only for individuals traveling to or residing in countries where cholera is endemic or epidemic.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003105 -->

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        <obo:IAO_0000115>LYMErix [Lyme Disease Vaccine (Recombinant OspA)] is a noninfectious recombinant vaccine developed and manufactured by SmithKline Beecham Biologicals. The vaccine contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003106 -->

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        <obo:IAO_0000118>DTP vaccine</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0003107 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003108 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003109 -->

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        <obo:IAO_0000118>Trihibit</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.drugs.com/mtm/trihibit.html</obo:IAO_0000119>
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        <rdfs:comment>Discontinued in 2011</rdfs:comment>
        <rdfs:label>Trihibit vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003115 -->

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        <obo:IAO_0000115>A vaccine against flu (influenza) in adults, especially in those who run an increased risk of experiencing associated complications in case they fall ill with flu.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>https://www.medicines.org.uk/emc/files/pil.6163.pdf</obo:IAO_0000119>
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        <rdfs:comment>The vaccine targets three strains of influenza virus, and is free of chicken/egg protein.</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/VO_0003116 -->

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        <obo:IAO_0000115>A vaccine used to prevent diphtheria and tetanus in individuals over 6 years of age.</obo:IAO_0000115>
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        <rdfs:comment>European/German vaccine</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/VO_0003117 -->

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        <obo:IAO_0000115>A combined live virus vaccine used to prevent measles, mumps, and rubella.</obo:IAO_0000115>
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        <rdfs:comment>need better source</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/VO_0003118 -->

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        <obo:IAO_0000115>A vaccine used to protect against measles, mumps, and rubella for 12-15 month-old individuals.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003119 -->

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        <obo:IAO_0000115>Active immunization against Haemophilius influenzae type b in recommended routinely for children at 24 months of age and for children at 15 months of age enrolled in child care facilities.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003120 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003121 -->

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        <obo:IAO_0000115>A Haemophilus influenzae type B conjugate vaccine manufactured by GSB.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003122 -->

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        <obo:IAO_0000115>A vaccine against diphtheria, tetanus, and pertussis.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003124 -->

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        <rdfs:label>obsolete Fluogen</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003126 -->

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        <obo:IAO_0000115>A TB vaccine that uses attenuated fowlpox strain FP9 to express mycobacterial mycolyl transferase Ag85A.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003129 -->

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        <obo:IAO_0000115>Pharmacotherapeutic group (ATC code): J 07 AN 01.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003130 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003131 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003133 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003134 -->

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        <obo:IAO_0000115>A Yellow fever virus vaccine that uses the live attenated 17D strain.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003135 -->

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        <obo:IAO_0000115>A Yellow fever virus vaccine that uses the live attenated 17DD strain.</obo:IAO_0000115>
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        <rdfs:comment>Two distinct strains of live attenuated yellow fever virus vaccine, 17D and 17DD, have been widely used. They have the same origin, from a yellow fever virus isolated from a patient with non fatal yellow fever named Asibi, from Ghana, in 1927. The 17D strain, used for vaccine production, corresponds to passage level 235-240 and the 17DD to a passage level 286-287. The comparison of the nucleotide sequences of all 17D vaccines showed an overall homology of 99.2%.</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/VO_0003136 -->

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        <obo:IAO_0000115>A YF-17DD vaccine t hat is manufactured by Bio-Manguinhos</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003138 -->

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        <obo:IAO_0000115>a licensed N. meningitidis vaccine that includes meningococcal polysaccharides from Groups A, C, Y and W-135 combined, and is manufactured by GSK.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003139 -->

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        <obo:IAO_0000115>It is live attenuated YFV vaccine strain 17D manufactured in China, France, Senegal, and the USA. In powder and solvent for suspension for injection in pre-filled syringe.</obo:IAO_0000115>
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        <rdfs:label>Stamaril vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003140 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003141 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003142 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003143 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003144 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003148 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003150 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003154 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003154">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001237"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003154</metadata:prefixIRI>
        <obo:IAO_0000115>A CpG DNA vaccine adjuvant that is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity.</obo:IAO_0000115>
        <obo:IAO_0000116>ISS 1018 is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity. ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B cells and interferon (IFN) -alpha, IFN-beta, interleukin-12 (IL-12), and tumor necrosis factor - alpha (TNF-alpha) by plasmacytoid dendritic cells (pDC). ISS 1018 CpG ODN promotes antigen presentation and co-stimulatory molecule expression. ISS 1018 is currently being investigated in combination with HBsAg vaccine as a prophylactic treatment for to prevent Hepatitis B in adults. It is also being investigated in combination with rituximab for treatment of b-cell or non-hodgkin&apos;s lymphoma.</obo:IAO_0000116>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>ISS 1018 CpG ODN</obo:IAO_0000118>
        <obo:IAO_0000118>ISS 1018 CpG oligodeoxynucleotide</obo:IAO_0000118>
        <obo:IAO_0000118>ISS-1018</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.cancer.gov/publications/dictionaries/cancer-drug/def/iss-1018-cpg-oligodeoxynucleotide</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.drugbank.ca/drugs/DB05463</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>ISS 1018 CpG ODN vaccine adjuvant</rdfs:label>
        <rdfs:seeAlso>DrugBank Accession number: DB05463</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003155 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003155</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>A recombinant vesicular stomatitis virus Indiana serotype (rVSV) vector vaccine taht  expresses Zaire GP</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/15937495</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>204</obo:VO_0005438>
        <obo:VO_0010151>702662</obo:VO_0010151>
        <obo:VO_1000000>Ebola Zaire vaccine, live, recombinant, 1mL dose</obo:VO_1000000>
        <obo:VO_1000001>Ebola Zaire vaccine, live, recombinant, 1mL dose</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rVSV-ZEBOV</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003156 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003156</metadata:prefixIRI>
        <obo:IAO_0000115>A human paillomavirus vaccine that has the vaccine antigen ingredient of monovalent non-infectious, L1 recombinant HPV-like particles (VLP).</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>HPV-16 L1 VLP</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/12854090</obo:IAO_0000119>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011108"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HPV-16 L1 VLP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003165 -->

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            </owl:Restriction>
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        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003165</metadata:prefixIRI>
        <obo:IAO_0000115>An inactivated Japanese encephalitis vaccine (JVax *) for use by certain travelers to and expatriates in Asia.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>J-Vax</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.cdc.gov/mmwr/preview/mmwrhtml/00018184.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>J-Vax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003167 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003167</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>A viral vaccine that protects against infection with Poliovirus administered orally.</obo:IAO_0000119>
        <obo:IAO_0000119>http://polioeradication.org/polio-today/polio-prevention/the-vaccines/opv/</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.who.int/biologicals/areas/vaccines/polio/opv/en/</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Oral Poliovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003168 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003168">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003168</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine that protects against diphtheria, tetanus, pertussis, and Haemophilus influenzae type B.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>DTaP-Hib vaccine</obo:IAO_0000118>
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        <obo:VO_0005438>50</obo:VO_0005438>
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        <obo:VO_1000000>DTaP-Haemophilus influenzae type b conjugate vaccine</obo:VO_1000000>
        <obo:VO_1000001>DTaP-Hib</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Contains pertussis in acellular form.</rdfs:comment>
        <rdfs:label>Diphtheria-Tetanus-Acellular Pertussis-Haemophilus b vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003169 -->

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        <obo:IAO_0000115>A combination vaccine with whole cell that protects against diphtheria, tetanus, pertussis, and Haemophilus influenzae type B.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003170 -->

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        <obo:IAO_0000115>A vaccine used to develop immunity to rabies.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003171 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003172 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003173 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003174 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003175 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003176 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000137"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003180</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects adolescents and adults from tetanus, diphtheria, and pertussis.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cdc.gov/vaccines/hcp/vis/vis-statements/tdap.html</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000137"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <obo:VO_0005438>115</obo:VO_0005438>
        <obo:VO_0010151>40213230</obo:VO_0010151>
        <obo:VO_1000000>tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine, adsorbed</obo:VO_1000000>
        <obo:VO_1000001>Tdap</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Tdap is different than the DTaP vaccine, which is given to infants and children in five doses, starting at 2 months of age.</rdfs:comment>
        <rdfs:label>TDAP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003444"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010441"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003181</metadata:prefixIRI>
        <obo:IAO_0000115>A measles virus vaccine manufactured outside of the U.S.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>Measles virus vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003418"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003444"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8781"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11041"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003182</metadata:prefixIRI>
        <obo:IAO_0000115>A Mumps-Rubella vaccine manufactured outside of the U.S.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8781"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11041"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>Mumps-Rubella vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003183 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003183">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000743"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003444"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003183</metadata:prefixIRI>
        <obo:IAO_0000115>A Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine manufactured outside of the U.S</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003184">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000742"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003444"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010435"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010436"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010445"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010447"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003184</metadata:prefixIRI>
        <obo:IAO_0000115>A Diphtheria-Tetanus-Pertussis-Poliovirus vaccine manufactured outside of the U.S.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>Diphtheria-Tetanus-Pertussis-Poliovirus vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003185">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000627"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003444"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003185</metadata:prefixIRI>
        <obo:IAO_0000115>A Haemophilis influenzae Type b capsular polysaccharide vaccine manufactured outside of the U.S.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>HIB Polysaccharide foreign to USA</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.drugs.com/mmx/haemophilus-influenzae-type-b-polysaccharide-vaccine.html</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>HIB Polysaccharide vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003186 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003186">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003444"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010439"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003186</metadata:prefixIRI>
        <obo:IAO_0000115>A Hepatitis B vaccine manufactured outside of the U.S.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ema.europa.eu/documents/product-information/hbvaxpro-epar-product-information_en.pdf</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>Hepatitis B vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003187 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003187">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000943"/>
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        <obo:IAO_0000115>A Diphtheria-Tetanus-Poliovirus vaccine manufactured outside of the U.S.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>Diphtheria-Tetanus-Poliovirus vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003188 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003188</metadata:prefixIRI>
        <obo:IAO_0000115>A Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine manufactured outside of the U.S.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ema.europa.eu/medicines/human/EPAR/hexyon</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003189 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003189">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003189</metadata:prefixIRI>
        <obo:IAO_0000115>A seasonal Influenza virus vaccine manufactured outside of the U.S.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.euro.who.int/en/health-topics/communicable-diseases/influenza/vaccination/types-of-seasonal-influenza-vaccine</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>seasonal influenza virus vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003190 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003190">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003190</metadata:prefixIRI>
        <obo:IAO_0000115>A Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine manufactured outside of the U.S</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>DTaP/IPV/Hib vaccine foreign to USA</obo:IAO_0000118>
        <obo:IAO_0000119>https://ca.gsk.com/media/590970/infanrix-ipv-hib.pdf</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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        <rdfs:label>Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine foreign to USA</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003191 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003191</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://vk.ovg.ox.ac.uk/ppv</obo:IAO_0000119>
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        <rdfs:comment>A pneumococcal vaccine manufactured outside of the U.S.</rdfs:comment>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>Pneumococcal vaccine foreign to USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003192">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003192</metadata:prefixIRI>
        <obo:IAO_0000115>An active immunizing combination agent that is used to prevent infection caused by certain groups of meningococcal bacteria and Haemophilus influenza type b (Hib) bacteria.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Meningococcal Conjugate and Haemophilis B Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003193 -->

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        <obo:IAO_0000115>A Meningicoccal Conjugate and Haemophilis B Vaccine manufactured outside of the U.S.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</rdfs:comment>
        <rdfs:label>Meningococcal Conjugate and Haemophilis B Vaccine foreign to USA</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003194 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003194</metadata:prefixIRI>
        <obo:IAO_0000115>A tick-borne encephalitis virus vaccine used to prevent subtype Far Eastern tick-borne encephalitis virus (formerly known as Russian Spring Summer encephalitis virus).</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.who.int/immunization/sage/1_TBE_PP_Draft_13_Mar_2011_SAGE_apr_2011.pdf?ua=1</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Spring Summer Encephalitis vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003195 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003195</metadata:prefixIRI>
        <obo:IAO_0000115>A polysaccharide vaccine to prevent typhoid caused Salmonella typhi. Acetone is used to inactivate culture, and dried.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Acetone-Dried Typhoid Vi Polysaccharide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003196 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003196</metadata:prefixIRI>
        <obo:IAO_0000118>acellular pertussis vaccine, inactivated</obo:IAO_0000118>
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        <rdfs:label>inactivated acellular pertussis vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003197 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003197</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine to protect individuals against infections caused by hepatitis A virus and typhoid fever bacteria.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003199 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003199</metadata:prefixIRI>
        <obo:IAO_0000118>B. pertussis pertactin vaccine</obo:IAO_0000118>
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        <rdfs:label>Bordetella pertussis pertactin vaccine, inactivated</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003200 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003201 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003202 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003203 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003204 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003205 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003206 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003207 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003208 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003209 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003210 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003211 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003212 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003214 -->

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        <obo:IAO_0000118>DT+IPV+HIB+HEPB vaccine</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Diphtheria-Tetanus-Poliovirus-Haemophilus B-Hepatitis B vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003215 -->

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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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    <!-- http://purl.obolibrary.org/obo/VO_0003216 -->

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        <obo:IAO_0000115>For the prevention of influenza caused by Influenza Virus, Types A and B. For the Southern
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Fluvax vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003217 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003218 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <rdfs:label>pneumococcal capsular polysaccharide type 12F vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003219 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003220 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003221 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003222 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <obo:VO_0003560>Streptococcus pneumoniae type 18C capsular polysaccharide antigen</obo:VO_0003560>
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        <rdfs:label>pneumococcal capsular polysaccharide type 18C vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003223 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <rdfs:label>pneumococcal capsular polysaccharide type 19A vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003224 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003225 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003226 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003227 -->

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        <obo:VO_0010151>40163690</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 22F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003228 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003228">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003228</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/830263</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0019370"/>
        <rdfs:label>obsolete 1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection [Recombivax]</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003229">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003229</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000950"/>
        <rdfs:label>obsolete Hepatitis A virus-Typhoid vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003230 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003230">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003150"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003230</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/830260</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0003198>830260</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003560>hepatitis B surface antigen vaccine 0.04 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>19133385</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B Surface Antigen vaccine 0.04 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003231 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003231">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003270"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019071"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003231</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1994352</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1994352</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003560>0.5 ML hepatitis B surface antigen vaccine 0.04 MG/ML Injection [Heplisav-B]</obo:VO_0003560>
        <obo:VO_0005279>Heplisav-B 20 MCG per 0.5 ML Injection</obo:VO_0005279>
        <obo:VO_0010151>793520</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:hasDbXref>CUI: C4534702</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 9712934, 9712933, 9712931, 9712937</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection [Heplisav-B]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003232">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003284"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010453"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003232</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/854962</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>854962</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <obo:VO_0003560>Streptococcus pneumoniae type 4 capsular polysaccharide antigen</obo:VO_0003560>
        <obo:VO_0005279>pneumococcal capsular polysaccharide type 4 vaccine</obo:VO_0005279>
        <obo:VO_0010151>40163698</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 4 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003233 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003233">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003233</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0019369"/>
        <rdfs:label>obsolete 1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003234">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003234</metadata:prefixIRI>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0019179"/>
        <rdfs:label>obsolete 0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003235 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003235">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010306"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003235</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1657332</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003560>influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46276184</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003236">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000950"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015346"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000950"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010438"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010451"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000137"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015346"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003236</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Hepatyrix</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000137"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatyrix vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003237 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003237">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010737"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015467"/>
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        </rdfs:subClassOf>
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    <!-- http://purl.obolibrary.org/obo/VO_0003238 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003239 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003240 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003241 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003242 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003243 -->

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        <rdfs:label>Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Recombivax]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003244</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/830253</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>830253</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003560>0.5 ML hepatitis B surface antigen vaccine 0.01 MG/ML Prefilled Syringe [Recombivax]</obo:VO_0003560>
        <obo:VO_0005279>Recombivax HB 5 MCG per 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>19133380</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Recombivax]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003245">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010737"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003245</metadata:prefixIRI>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Recombivax Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003246 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003246">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003284"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010453"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003246</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/854970</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>854970</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <obo:VO_0003560>Streptococcus pneumoniae type 8 capsular polysaccharide antigen</obo:VO_0003560>
        <obo:VO_0005279>pneumococcal capsular polysaccharide type 8 vaccine</obo:VO_0005279>
        <obo:VO_0010151>40163706</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 8 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003247 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003247">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003247</metadata:prefixIRI>
        <metadata:treeView rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <obo1:part_of rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <obo:IAO_0000115>The site that is the part of the host body and the entrance point where a vaccine is administered. </obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:comment>it is not the natural anatomical part where the body has access toward outside, such as mouth or nose. But rather the holes on the skin made by needdles used for vaccination.</rdfs:comment>
        <rdfs:label>vaccination site</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003248 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003248">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003248</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/854958</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>854958</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <obo:VO_0003560>Streptococcus pneumoniae type 3 capsular polysaccharide antigen</obo:VO_0003560>
        <obo:VO_0005279>pneumococcal capsular polysaccharide type 3 vaccine</obo:VO_0005279>
        <obo:VO_0010151>40163694</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 3 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003249 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003249">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003249</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/854960</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>854960</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <obo:VO_0003560>Streptococcus pneumoniae type 33F capsular polysaccharide antigen</obo:VO_0003560>
        <obo:VO_0005279>pneumococcal capsular polysaccharide type 33F vaccine</obo:VO_0005279>
        <obo:VO_0010151>40163696</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 33F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003250">
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003250</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/854966</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>854966</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <obo:VO_0003560>Streptococcus pneumoniae type 6B capsular polysaccharide antigen</obo:VO_0003560>
        <obo:VO_0005279>pneumococcal capsular polysaccharide type 6B vaccine</obo:VO_0005279>
        <obo:VO_0010151>40163702</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 6B vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003251 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003251">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001236"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002495"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003251</metadata:prefixIRI>
        <obo:IAO_0000115>A trivalent inactive influenza virus vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Flu-imune</obo:IAO_0000118>
        <obo:IAO_0000119>https://cvi.asm.org/content/cdli/1/1/16.full.pdf</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Vaccine sold for 1993-1994 influenza season.</rdfs:comment>
        <rdfs:label>Flu-Imune vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003252 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003253 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003254 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003255 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003256 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003257 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003258 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003259 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003260 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003261 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003262 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003263 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003264 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003265 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003266 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003267 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003269 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003270 -->

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        <obo:VO_0005279>varicella-zoster virus vaccine live (Oka-Merck) strain 1350 PFU per 0.5 ML Injection</obo:VO_0005279>
        <obo:VO_0010151>42800030</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML Injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003277 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003277">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000419"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8659"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003277</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1292424</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8659"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003278">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003273"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003278</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1292436</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8659"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 20000 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003279 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003279">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003273"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003279</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1292430</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8659"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1292430</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <obo:VO_0003560>varicella-zoster virus vaccine live (Oka-Merck) strain 29800 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>42800033</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003280">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003280</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1292432</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0003272"/>
        <rdfs:label>obsolete 0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Injection</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003281">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000124"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003281</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1658013</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1658013</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <obo:VO_0003560>varicella-zoster virus vaccine live (Oka-Merck) strain Injection [Zostavax]</obo:VO_0003560>
        <obo:VO_0010151>46275142</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection [Zostavax]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003282 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003282">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003281"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003282</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1292433</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8659"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1292433</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <obo:VO_0003560>varicella-zoster virus vaccine live (Oka-Merck) strain 29800 UNT/ML [Zostavax]</obo:VO_0003560>
        <obo:VO_0010151>42800036</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML [Zostavax]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003283 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003283">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003282"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003283</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1292435</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8659"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1292435</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <obo:VO_0003560>0.65 ML varicella-zoster virus vaccine live (Oka-Merck) strain 29800 UNT/ML Injection [Zostavax]</obo:VO_0003560>
        <obo:VO_0005279>Zostavax 19,400 PFU per 0.65 ML Injection</obo:VO_0005279>
        <obo:VO_0010151>42800035</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Injection [Zostavax]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003284 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003286 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003287 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003288 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003289 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003290 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003297 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003298 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003299 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003300 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003301 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003302 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003303 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003304 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003306 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003307 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003308 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003310 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003311 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003312 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003313 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003314 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003315 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003316 -->

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        <obo:IAO_0000115>A vaccine that can be given to children after the age of 2 months up to 2 years to prevent infectious diseases caused by Haemophilus influenzae type b (Hib) and Neisseria meningitidis group C (MenC) bacteria.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>Menitorix vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003317 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003099>SHINGRIX</obo:VO_0003099>
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        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM581605.pdf</obo:VO_0003161>
        <obo:VO_0003162>125614</obo:VO_0003162>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shingrix vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003318 -->

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        <obo:IAO_0000115>A vaccine against tetanus, diphtheria, pertussis, and inactivated poliovirus manufactured outside of the U.S.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003319 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003320 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003321 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003322 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003323 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <obo:VO_0003198>854931</obo:VO_0003198>
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        <rdfs:label>pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003324 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003324</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 19F vaccine 0.05 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003325 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 2 vaccine 0.05 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003326 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 20 vaccine 0.05 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003327 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <rdfs:label>pneumococcal capsular polysaccharide type 22F vaccine 0.05 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003328 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <rdfs:label>pneumococcal capsular polysaccharide type 3 vaccine 0.05 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003329 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003330 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003331 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003332 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003333 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003334 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003336 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003348 -->

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        <obo:IAO_0000115>A vaccine-induced up-regulation gene expression that occurs in live attenuated vaccine and compared with the host system infected with live wild type virulent strain which is the parent strain of this live attenuated vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003349 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003350 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003351 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003352 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003353 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003354 -->

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        <obo:VO_0003198>762601</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>Salmonella typhi Ty21a live antigen Delayed Release Oral Capsule [Vivotif]</obo:VO_0003560>
        <obo:VO_0010151>40148796</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0018846"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid Vaccine Live Ty21a Delayed Release Oral Capsule [Vivotif]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003356 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003356</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>762602</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>Salmonella typhi Ty21a live antigen 2000000000 UNT Delayed Release Oral Capsule [Vivotif]</obo:VO_0003560>
        <obo:VO_0005279>Vivotif Berna 2,000,000,000 UNT Delayed Release Oral Capsule</obo:VO_0005279>
        <obo:VO_0010151>19129379</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0018846"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid Vaccine Live Ty21a 2000000000 UNT Delayed Release Oral Capsule [Vivotif]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003357 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003357</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1187406</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vivotif Oral Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003358 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vivotif Pill</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003359 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>1601405</obo:VO_0003198>
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        <obo:VO_0003560>meningococcal group B vaccine Prefilled Syringe [Bexsero]</obo:VO_0003560>
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        <rdfs:label>meningococcal group B vaccine Prefilled Syringe [Bexsero]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003360 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003361 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003362 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <rdfs:label>Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003363 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003364 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003365 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003366 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003367 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003368 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003369 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003370 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003371 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003372 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003373 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003374 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003375 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003376 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003377 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003378 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003379 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003380 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003381 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003382 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003383 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003384 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003385 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003386 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003387 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003388 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003389 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003391 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003392 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003393 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003394 -->

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        <obo:IAO_0000115>An inactivated quadrivalent influenza vaccine against 2 influenza A strains and 2 influenza B strains for infants 6 months up to 23 months, and if needed it can be administered to children 2 to 17 years old with compromised immune systems and those considered vulnerable and high risk.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003395 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>805373</obo:VO_0003198>
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    <!-- http://purl.obolibrary.org/obo/VO_0003396 -->

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        <obo:IAO_0000115>A clostridium tetani vaccine that consists of formaldehyde inactivated tetanospasmin (aka tetanus toxoid).</obo:IAO_0000115>
        <obo:IAO_0000117>Hector Guzman-Orozco</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003397 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003398 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003399 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003400 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003401 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003402 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003403 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003404 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003405 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003406 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003407 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003408 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003409 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003413 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003414 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003415 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003416 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003417 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003418 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003419 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003420 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003421 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003422 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003423 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003424 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003425 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003426 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003427 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003428 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003429 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003430 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003431 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003432 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003433 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003434 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003435 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003436 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003437 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003438 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003439 -->

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        <obo:IAO_0000115>Vaccine component role inheres in a vaccine vector.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003440 -->

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        <obo:IAO_0000115>A trivalent influenza vaccine containing two strains of influenza A and one strain of influenza B for use in people 18 years to 64 years for use during the 2012-2013 season.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003441 -->

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        <obo:IAO_0000115>Meningococcal conjugate vaccine, which contains four of the most common types of meningococcal bacteria (serogroups A, C, W, and Y), is used to prevent infection caused by meningococcal bacteria.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003442 -->

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        <obo:IAO_0000115>A DTaP vaccine used to keep up protection (immunity) against diphtheria, tetanus (lockjaw) and pertussis (whooping cough) in children and adults who have been vaccinated for these diseases in the past.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003443 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003444 -->

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        <obo:IAO_0000115>This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003445 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003446 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003447 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003448 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003449 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003450 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003451 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003452 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003453 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003454 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003455 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003456 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003457 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003459 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003460 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003461 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003462 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003463 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <rdfs:label>1 ML Hepatitis A Vaccine, Inactivated 50 UNT/ML Prefilled Syringe [Vaqta]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003464 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003465 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003466 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003467 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003468 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003470 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003472 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003472</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1657225</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <obo:VO_0003560>influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46276099</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003473 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010303"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003473</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1723999</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <obo:VO_0003560>influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>35606409</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003474 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010303"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003474</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1664468</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <obo:VO_0003560>influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46287742</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003475 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003475">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003475</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1657130</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/South Australia/55/2014 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003476 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003476">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010298"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003476</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1657132</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <obo:VO_0003560>influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46275997</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003477 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003477">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003477</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1657127</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Brisbane/10/2010 (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003478 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003478">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003478</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1657129</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003560>influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46275994</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003479 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003479">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015086"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003479</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1657226</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fludb.org/brc/fluStrainDetails.spg?strainName=B/Brisbane/60/2008&amp;decorator=influenza</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Brisbane/60/2008 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003480 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003480">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010304"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003480</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1657227</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46276101</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003481 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003481">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003481</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1664469</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46287743</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003482 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003482</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1661110</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46276042</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003483 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003483</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1801177</obo:VO_0003198>
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        <obo:VO_0003560>influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>36249504</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003484 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003484">
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        <obo:IAO_0000115>Vaccine that protects against Neisseriales infection.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Neisseriales</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine against Neisseriales bacterial infection</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Neisseriaceae</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_206351"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neisseriales vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003485 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003485">
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <obo:VO_0003198>1946982</obo:VO_0003198>
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        <obo:VO_0003560>influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>792418</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003486 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003486">
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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1657133</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Utah/9/2014 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003487 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <obo:VO_0003198>1657135</obo:VO_0003198>
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        <obo:VO_0003560>influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46276000</obo:VO_0010151>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003488 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1657228</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Phuket/3073/2013 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003489 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <obo:VO_0003198>1657229</obo:VO_0003198>
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        <obo:VO_0003560>influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46276103</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003490 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>1660923</obo:VO_0003198>
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        <obo:VO_0003560>influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>46276013</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003491 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003492 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003493 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003494 -->

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        <obo:IAO_0000115>Vaccine that protects against Spirochaetes infection.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0003495 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <rdfs:label>human influenza virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003496 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003497 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <rdfs:label>influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003498 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003499 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003500 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003501 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003502 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003503 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003504 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003505 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003506 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003507 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003508 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003509 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003510 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003511 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003512 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003513 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003514 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003515 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003516 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003517 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003518 -->

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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Borreliella.</obo:IAO_0000115>
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        <rdfs:label>Borreliella vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003519 -->

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        <rdfs:label>human influenza B virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003520 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <rdfs:label>human influenza B-like virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003521 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003522 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003523 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003524 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003525 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003526 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003527 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003528 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003528</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1429576</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1429576</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>43532652</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003529 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003529">
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003529</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1429589</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        <obo:VO_0003198>1429589</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>43532656</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003530 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003530">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003530</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1543760</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 50000000 UNT/ML</obo:VO_0003560>
        <obo:VO_0003560>influenza B virus vaccine, B-Massachusetts-2-2012-like virus 50000000 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>43137645</obo:VO_0010151>
        <obo:VO_0010151>45776787</obo:VO_0010151>
        <obo:VO_0010152>OMOP472229</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus vaccine, B-Massachusetts-2-2012-like virus 50000000 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003531 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003531">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003531</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1224"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Proteobacteria vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003532 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003532">
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28216"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Betaproteobacteria vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003533 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003533</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Yersiniaceae infection.</obo:IAO_0000115>
        <obo:IAO_0000118>vacccine against Yersiniaceae</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Yersiniaceae</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1903411"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersiniaceae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003534 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003534">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Corynebacterium.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Corynebacterium</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Corynebacterium</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1716"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Corynebacterium vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003535 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003535">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003531"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1236"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Gammaproteobacteria vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003536 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003536</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Bacillus.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Bacillus</obo:IAO_0000118>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003537 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003537">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Varicellovirus.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Varicellovirus</obo:IAO_0000118>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicellovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003538 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003538</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Papillomaviridae.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>vaccine against Papillomaviridae</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Papillomaviridae</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_151340"/>
        <oboInOwl:hasDbXref>MeSH: D053918</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Papillomaviridae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003539 -->

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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Orthopoxvirus.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Orthopoxvirus</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Orthopoxvirus</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10242"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Orthopoxvirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003540 -->

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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003540</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Orthohepadnavirus infection.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Orthohepadnavirus</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Orthohepadnavirus</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10405"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Orthohepadnavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003541 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003541">
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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Reoviridae.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Reoviridae</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Reoviridae</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2732541"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Reoviridae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003542 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003542">
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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Sedoreovirinae.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Sedoreovirinae</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Sedoreovirinae</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2946186"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Sedoreovirinae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003543 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003543">
        <owl:equivalentClass>
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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Morbillivirus.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Morbillivirus</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Morbillivirus</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11229"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Morbillivirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003544 -->

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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Rubulavirus.</obo:IAO_0000115>
        <obo:IAO_0000118>vaccine against Rubulavirus</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Rubulavirus</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39744"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rubulavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003545 -->

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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Lyssavirus.</obo:IAO_0000115>
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        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Lyssavirus</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11286"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lyssavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003546 -->

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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Flaviviridae.</obo:IAO_0000115>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11050"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flaviviridae vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003547 -->

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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Enterovirus.</obo:IAO_0000115>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12059"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Enterovirus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003548 -->

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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Hepatovirus.</obo:IAO_0000115>
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        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Hepatitis_A#Virology</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12091"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatovirus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003549 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8781"/>
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        <obo:IAO_0000115>A vaccine that is used against an infection by a pathogen under Rubivirus.</obo:IAO_0000115>
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        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Rubella_virus</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8781"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rubivirus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003550 -->

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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28211"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Alphaproteobacteria vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003551 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003551</metadata:prefixIRI>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91347"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Enterobacterales vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003552 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003552">
        <owl:equivalentClass>
            <owl:Class>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_543"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003551"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_543"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003552</metadata:prefixIRI>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_543"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Enterobacteriaceae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003553 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003553">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_203692"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_203692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003553</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Spirochaetia infection.</obo:IAO_0000115>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_203692"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Spirochaetia vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003554 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003554">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1239"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1239"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003554</metadata:prefixIRI>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1239"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Firmicutes vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003555 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003555">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91061"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003554"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91061"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003555</metadata:prefixIRI>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_91061"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacilli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003556 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003556">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003554"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003556</metadata:prefixIRI>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lactobacillales vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003559 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003559">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003570"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003559</metadata:prefixIRI>
        <obo:IAO_0000118>Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]) 0.5 ML Prefilled Syringe</obo:IAO_0000118>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/901644</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>901644</obo:VO_0003198>
        <obo:VO_0003560>0.5 ML Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumo...</obo:VO_0003560>
        <obo:VO_0005279>Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]) 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>40173508</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Prevnar 13 vaccine 0.5 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003561 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003561">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003284"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010453"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003561</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/854974</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>854974</obo:VO_0003198>
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        <obo:VO_0003560>Streptococcus pneumoniae type 9V capsular polysaccharide antigen</obo:VO_0003560>
        <obo:VO_0005279>pneumococcal capsular polysaccharide type 9V vaccine</obo:VO_0005279>
        <obo:VO_0010151>40163710</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 9V vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003562 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003562">
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003562</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 9V vaccine 0.05 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003563 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003563">
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003563</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3236244</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3843751</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pneumovax 23 Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003564 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003564">
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        <rdfs:subClassOf>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>Pneumovax 23 Injection</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003565 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>CUI: C3887855</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7253077, 7253108, 7253095</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PNEUMOVAX 23 0.5 ML Injection</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003566 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>RXAUI: 2977679, 7253371, 3270831</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PNEUMOVAX 23 vaccine Injectable Solution</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003567 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>RXAUI: 6400287</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PNEUMOVAX 23 vaccine Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003568 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>PNEUMOVAX 23 vaccine 0.5 ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003569 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Prevnar 13 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003570 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003571 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003578 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003581 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003582 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003583 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003584 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003585 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003586 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003587 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003589 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Fluzone 2017-2018 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003590 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003590</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0003591 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003592 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003593 -->

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        <obo:VO_0003198>1928344</obo:VO_0003198>
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        <obo:VO_0005279>Fluzone 2017-2018 high-dose vaccine 0.5 ML Prefilled Syringe</obo:VO_0005279>
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    <!-- http://purl.obolibrary.org/obo/VO_0003594 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003595 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003596 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003597 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010412"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019046"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003597</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003603"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003604"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003605"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2050421</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2050421</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone 2018-2019]</obo:VO_0003560>
        <obo:VO_0010151>35200034</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C4719044</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 10289782</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone 2018-2019 high-dose vaccine Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003598 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003598">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003597"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010412"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019046"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003598</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2050423</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2050423</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>0.5 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2018-2019]</obo:VO_0003560>
        <obo:VO_0005279>Fluzone 2018-2019 high-dose vaccine 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>35201913</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C4719046</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 10289784, 10289785, 10289786</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone 2018-2019 high-dose vaccine 0.5 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003599 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003599">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003599</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1794331</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4256803</rdfs:comment>
        <rdfs:comment>RXAUI: 8222490</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003600 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003600">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003600</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1928289</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4490394</rdfs:comment>
        <rdfs:comment>RXAUI: 9198755</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza A virus A/Michigan/45/2015 (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003601 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003601">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003601</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2048564</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4704008</rdfs:comment>
        <rdfs:comment>RXAUI: 10279285</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003602 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003602">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015086"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003602</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2048563</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4704007</rdfs:comment>
        <rdfs:comment>RXAUI: 10279284</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza B virus B/Maryland/15/2016 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003603 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003603">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010316"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003603</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2050417</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>35200031</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003604 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003604">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010313"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003604</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1928338</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003560>influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>1593351</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003605 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003605">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010317"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003605</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2050416</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>35200030</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003606 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003606</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003607 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0003608 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003609 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003610 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003614 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1537559</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / influenza A-California-7-2009-(H1N1)v-like virus vaccine / influenza B virus vaccine B/Brisbane/60/2008 antigen / influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluzone Quadrivalent 2014-2015 Formula]</obo:VO_0003560>
        <obo:VO_0010151>44818126</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C3819658</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 6338536</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2014-2015 Formula Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003615 -->

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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003615</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1598361</obo:VO_0003198>
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        <obo:VO_0003560>0.1 ML influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / influenza A-California-7-2009-(H1N1)v-like virus vaccine 0.09 MG/ML / influenza B virus vaccine B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2014-2015 Formula]</obo:VO_0003560>
        <obo:VO_0005279>Fluzone Quadrivalent 2014-2015 Formula 0.1 ML Prefilled Syringe</obo:VO_0005279>
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        <oboInOwl:hasDbXref>CUI: C3871481</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 6821896, 6821899</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2014-2015 Formula 0.1 ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003616 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003616</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Fluzone Quadrivalent 2015-2016 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003617 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003617</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>CUI: C4047088</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7255360</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2015-2016 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003618 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003619 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003620 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003621 -->

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        <rdfs:label>Fluzone Quadrivalent 2015-2016 vaccine Injectable Suspension</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003623 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003624 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003625 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003626 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003627 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003628 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003629 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003631</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1801188</obo:IAO_0000119>
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        <obo:VO_0003198>1801188</obo:VO_0003198>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Fluzone Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0010151>36249515</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:hasDbXref>CUI: C4271673</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8237172</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2016-2017 Formula Injection</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003632 -->

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            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010413"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019058"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003632</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1801189</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1801189</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0005279>Fluzone Quadrivalent 2016-2017 Formula 0.5 ML Injection</obo:VO_0005279>
        <obo:VO_0010151>36249516</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:hasDbXref>CUI: C4270930</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8237177, 8237176, 8237173</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>RXN STRENGTH: 0.03 MG/ML (expressed as influenza A virus A/California/7/2009 (H1N1) antigen) / 0.03 MG/ML (expressed as influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen) / 0.03 MG/ML (expressed as influenza B virus B/Brisbane/60/2008 antigen) / 0.03 MG/ML (expressed as influenza B virus B/Phuket/3073/2013 antigen)</rdfs:comment>
        <rdfs:label>Fluzone Quadrivalent 2016-2017 Formula 0.5 ML Injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003633 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010413"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003633</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1801193</obo:VO_0003198>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0005279>Fluzone Quadrivalent 2016-2017 Injectable Suspension</obo:VO_0005279>
        <obo:VO_0010151>36249520</obo:VO_0010151>
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        <oboInOwl:hasDbXref>CUI: C4224210</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8237184, 8237186, 8237185</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>RXN STRENGTH: 0.03 MG/ML (expressed as influenza A virus A/California/7/2009 (H1N1) antigen) / 0.03 MG/ML (expressed as influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen) / 0.03 MG/ML (expressed as influenza B virus B/Brisbane/60/2008 antigen) / 0.03 MG/ML (expressed as influenza B virus B/Phuket/3073/2013 antigen)</rdfs:comment>
        <rdfs:label>Fluzone Quadrivalent 2016-2017 Injectable Suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003634 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003634</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1801073</obo:VO_0003198>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0010151>36249402</obo:VO_0010151>
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        <oboInOwl:hasDbXref>CUI: C4271678</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8236909</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2016-2017 vaccine Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003635 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003635</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1801075</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
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        <obo:VO_0005279>Fluzone Quadrivalent 2016-2017 vaccine 0.1 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>36249404</obo:VO_0010151>
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        <oboInOwl:hasDbXref>RXAUI: 8236914, 8237166, 8236911</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2016-2017 vaccine 0.1 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003636 -->

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        <obo:VO_0003560>0.25 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0005279>Fluzone Quadrivalent 2016-2017 vaccine 0.25 ML Prefilled Syringe</obo:VO_0005279>
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    <!-- http://purl.obolibrary.org/obo/VO_0003637 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003638 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003639 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003640 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003641 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003642 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003643 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003644 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003645 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003646 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003647 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003648 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003649 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003654 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003655 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003656 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003657 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003658 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003659 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003660 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003661 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003662 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003663 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003664 -->

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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2048959</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>1559889</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003665 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003665</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>RXAUI: 3850144</obo:IAO_0000119>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1186641</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9682"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11089"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3240393</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>YF-Vax Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003666 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003666">
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003666</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1658240</obo:VO_0003198>
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        <obo:VO_0003560>yellow fever virus strain 17D-204 live antigen Injection [YF-Vax]</obo:VO_0003560>
        <obo:VO_0010151>46275269</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:hasDbXref>CUI: C4033799</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7252581</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>YF-VAX Injection</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003667 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003666"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003667</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003381"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0005279>YF-Vax 0.5 ML Injection</obo:VO_0005279>
        <obo:VO_0010151>46275270</obo:VO_0010151>
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        <oboInOwl:hasDbXref>CUI: C4019051</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7252591, 7252583, 7252590, 7252582</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>YF-VAX 0.5 ML Injection</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003668 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003668</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003381"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>RXAUI: 4610776, 4610775, 7251861</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>YF-Vax 4000 UNT/ML Injectable Suspension</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003669 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003669</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>YF-Vax Injectable Suspension</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003670 -->

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        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003381"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>804191</obo:VO_0003198>
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        <obo:VO_0003560>yellow fever virus strain 17D-204 live antigen 4000 UNT/ML [YF-Vax]</obo:VO_0003560>
        <obo:VO_0010151>19131661</obo:VO_0010151>
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        <oboInOwl:hasDbXref>RXAUI: 2860284</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML [YF-Vax]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003671 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003671</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3238354</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3843231</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PedvaxHIB Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003672 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>798449</obo:VO_0003198>
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        <obo:VO_0003560>Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.265 MG/ML [PedvaxHIB]</obo:VO_0003560>
        <obo:VO_0010151>19030111</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344386</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML [PedvaxHIB]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003673 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003560>Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine Injection [PedvaxHIB]</obo:VO_0003560>
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        <oboInOwl:hasDbXref>RXAUI: 7251648</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PedvaxHIB vaccine Injection</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003674 -->

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        <obo:IAO_0000115>Vaccine component that is used to deliver genetic code into the cells to produce antigen. </obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>vaccine vector</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003675 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003675</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>CUI: C4026630</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>TUI: T116, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluvirin 2015-2016 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003676 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003677 -->

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        <obo:VO_0003560>influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluvirin 2015-2016]</obo:VO_0003560>
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    <!-- http://purl.obolibrary.org/obo/VO_0003678 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003679 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003680 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003681 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003682 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003683 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003685 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003686 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003687 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003688 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003689 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003690 -->

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        <obo:VO_0005279>Fluvirin 2017-2018 vaccine Injectable Suspension</obo:VO_0005279>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluvirin 2017-2018 vaccine Injectable Suspension</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003691 -->

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        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluvirin 2017-2018]</obo:VO_0003560>
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        <rdfs:label>Fluvirin 2017-2018 vaccine Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003692 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003693 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0003694 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003695 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003696 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003697 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003698 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003699 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003700 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003701 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003702 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003703 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003704 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003705 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003707 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010412"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018975"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003711</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2048964</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2048964</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluarix Quadrivalent 2018-2019]</obo:VO_0003560>
        <obo:VO_0010151>1559892</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C4704191</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 10279941</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluarix Quadrivalent 2018-2019 vaccine Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003712 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003712">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003711"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010412"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018975"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003712</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2048966</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2048966</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2018-2019]</obo:VO_0003560>
        <obo:VO_0005279>Fluarix Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>1560162</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C4704193</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 10279943, 10279945, 10279944</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluarix Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003713 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003713">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003713</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1928290</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4490395</rdfs:comment>
        <rdfs:comment>RXAUI: 9198756</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003714 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003714">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010314"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003714</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1928300</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003560>influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>1593184</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003715 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003715">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018937"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000006"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000578"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000200"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003475"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003715</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1661803</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000200"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003475"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003488"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <oboInOwl:hasDbXref>CUI: C4020099</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7264715</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Afluria 2015-2016 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003716 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003716">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003715"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018937"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003716</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1661806</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C4047061</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7264718</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Afluria 2015-2016 Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003717 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003717">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003715"/>
        <rdfs:subClassOf>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1661804</obo:VO_0003198>
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    <!-- http://purl.obolibrary.org/obo/VO_0003718 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003719 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003720 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003721 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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    <!-- http://purl.obolibrary.org/obo/VO_0003722 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>CUI: C4271746</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8234385</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Afluria 2016-2017 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003723 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003560>influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Afluria 2016-2017]</obo:VO_0003560>
        <obo:VO_0010151>36249261</obo:VO_0010151>
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    <!-- http://purl.obolibrary.org/obo/VO_0003724 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003725 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003726 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003727 -->

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        <obo:VO_0003560>influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML Injectable Suspension [Afluria 2017-2018]</obo:VO_0003560>
        <obo:VO_0005279>Afluria 2017-2018 vaccine Injectable Suspension</obo:VO_0005279>
        <obo:VO_0010151>793961</obo:VO_0010151>
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        <rdfs:label>Afluria 2017-2018 vaccine Injectable Suspension</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003731 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1942130</obo:VO_0003198>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria 2017-2018]</obo:VO_0003560>
        <obo:VO_0010151>793954</obo:VO_0010151>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Afluria 2017-2018 vaccine Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003732 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003732</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1942132</obo:VO_0003198>
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        <obo:VO_0003560>0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML Prefilled Syringe [Afluria 2017-2018]</obo:VO_0003560>
        <obo:VO_0005279>Afluria 2017-2018 vaccine 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>793956</obo:VO_0010151>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Afluria 2017-2018 vaccine 0.5 ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003733 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Afluria 2018-2019 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003734 -->

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        <oboInOwl:hasDbXref>CUI: C4719176</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Afluria 2018-2019 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003735 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003736 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003737 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003738 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003739 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003740 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003741 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003742 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003744 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003745 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003746 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003747 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003748 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003749 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003750 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003751 -->

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        <obo:VO_0003198>1799205</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Flulaval Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0005279>FLULAVAL QUADRIVALENT 2016-2017 vaccine Injectable Suspension</obo:VO_0005279>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FluLaval Quadrivalent 2016-2017 vaccine Injectable Suspension</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003761 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1799104</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flulaval Quadrivalent 2016-2017]</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flulaval Quadrivalent 2016-2017 vaccine Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003762 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003763 -->

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        <rdfs:label>FluLaval Quadrivalent 2015-2016 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003764 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003765 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003766 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003767 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003768 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003769 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003770 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003771 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003772 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003773 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003778 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003779 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003780 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003781 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003782 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1657142</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax 2015-2016]</obo:VO_0003560>
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    <!-- http://purl.obolibrary.org/obo/VO_0003783 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0005279>FLUCELVAX 2015-2016 vaccine 0.5 ML Prefilled Syringe</obo:VO_0005279>
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    <!-- http://purl.obolibrary.org/obo/VO_0003784 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003785 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003786 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018996"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003786</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003478"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003487"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003659"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003790"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1801608</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1801608</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <obo:VO_0003560>influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0010151>40220718</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C4276184</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8238454</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2016-2017]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003787 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003787">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010413"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003787</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1801609</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1801609</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0010151>40220719</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C4276248</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8238455</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flucelvax Quadrivalent 2016-2017 Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003788 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003788">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003787"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010413"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003788</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1801611</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>0.5 ML influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0005279>FLUCELVAX QUADRIVALENT 2016-2017 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>40220721</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C4256265</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8238461, 8238460, 8238457</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flucelvax Quadrivalent 2016-2017 0.5 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003789 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003789">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015086"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003789</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1801603</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4276030</rdfs:comment>
        <rdfs:comment>RXAUI: 8238449</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza B virus B/Hong Kong/259/2010 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003790 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003790">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010310"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003790</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1801604</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>40220715</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003791 -->

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                <owl:intersectionOf rdf:parseType="Collection">
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003070"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010433"/>
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        <rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010414"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003791</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1928533</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003486"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003601"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003713"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003789"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:hasDbXref>CUI: C4325207</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 9199341</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T116, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0003792 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003793 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003794 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003795 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003796 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010414"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018997"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003796</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1928540</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1928540</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2017-2018]</obo:VO_0003560>
        <obo:VO_0005279>Flucelvax Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>1593689</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C4325069</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 9199352, 9199361, 9199348</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flucelvax Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003797 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003797">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003317"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019085"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003797</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1986826</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C4530100</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 9698281</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shingrix Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003798 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003798">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003317"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003803"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003798</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003803"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1986827</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1986827</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <obo:VO_0003560>varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML [Shingrix]</obo:VO_0003560>
        <obo:VO_0010151>792783</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C4530101</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 9698282</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML [Shingrix]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003799 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003799">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003797"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020282"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003799</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>0.5 ML Shingrix 0.1 MG/ML Injection</obo:IAO_0000118>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1986830</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1986830</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <obo:VO_0003560>0.5 ML varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML Injection [Shingrix]</obo:VO_0003560>
        <obo:VO_0005279>Shingrix vaccine 0.5 ML Injection</obo:VO_0005279>
        <obo:VO_0010151>792786</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:hasDbXref>RXAUI: 9698706, 9698285, 9698287, 9698286</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shingrix vaccine 0.5 ML Injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003800 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003800">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003799"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003800</metadata:prefixIRI>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Shingrix 0.1 MG/ML Injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003801 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003801">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010792"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003801</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1986821</obo:IAO_0000119>
        <obo:VO_0003198>1986821</obo:VO_0003198>
        <obo:VO_0003560>varicella zoster virus glycoprotein E</obo:VO_0003560>
        <obo:VO_0010151>792777</obo:VO_0010151>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>CUI: C0061673</rdfs:comment>
        <rdfs:comment>RXAUI: 9698276</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>Varicella zoster virus glycoprotein E</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003802 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003802">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003801"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003802</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1986820</obo:IAO_0000119>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4530095</rdfs:comment>
        <rdfs:comment>RXAUI: 9698275</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>Varicella zoster virus glycoprotein E, recombinant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003803 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003803">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010328"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003803</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1986822</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <obo:VO_0003560>varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>792778</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003804 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003804">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003804</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1664639</obo:IAO_0000119>
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        <rdfs:comment>RXAUI: 7266972</rdfs:comment>
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        <rdfs:label>influenza A virus A/Bolivia/559/2013 (H1N1) antigen</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003805 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <obo:VO_0003198>1664467</obo:VO_0003198>
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        <obo:VO_0010151>46287741</obo:VO_0010151>
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        <rdfs:label>influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003806 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003807 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003808 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003809 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003809</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>1664644</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML Nasal Spray [Flumist 2015-2016]</obo:VO_0003560>
        <obo:VO_0010151>46287293</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0019100"/>
        <oboInOwl:hasDbXref>CUI: C4026361</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7266797, 7266977, 7266796</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FluMist Quadrivalent, 2015-2016 Formula Nasal Spray</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003810 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003810</metadata:prefixIRI>
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        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003805"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1664640</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML [Flumist 2015-2016]</obo:VO_0003560>
        <obo:VO_0010151>46287291</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C4050879</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML [Flumist 2015-2016]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003811 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003811">
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4276025</rdfs:comment>
        <rdfs:comment>RXAUI: 8238906</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza A virus A/New Caledonia/71/2014 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003812 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003812">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010311"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003812</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1801822</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003813 -->

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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003813</metadata:prefixIRI>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1801826</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML [Flumist Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0010151>40220775</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C4276182</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003814 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0019100"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003814</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>FluMist Quadrivalent, Live Attenuated, 2016-2017 Formula Nasal Spray</obo:IAO_0000118>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1801830</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1801830</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML Nasal Spray [Flumist Quadrivalent 2016-2017]</obo:VO_0003560>
        <obo:VO_0010151>40220779</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0019100"/>
        <oboInOwl:hasDbXref>CUI: C4224207</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8239001, 8239002, 8239000</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FluMist Quadrivalent, 2016-2017 Formula Nasal Spray</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003815 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003815</metadata:prefixIRI>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1946985</obo:IAO_0000119>
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        <obo:VO_0003198>1946985</obo:VO_0003198>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <obo:VO_0003560>influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML [Flumist Quadrivalent 2017-2018]</obo:VO_0003560>
        <obo:VO_0010151>792421</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C4529659</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 9278648</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML [Flumist Quadrivalent 2017-2018]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003816 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003808"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003816</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>FluMist Quadrivalent, Live Attenuated, 2017-2018 Formula Nasal Spray</obo:IAO_0000118>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1946986</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1946986</obo:VO_0003198>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray [Flumist Quadrivalent 2017-2018]</obo:VO_0003560>
        <obo:VO_0010151>792422</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0019100"/>
        <oboInOwl:hasDbXref>CUI: C4522486</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 9278652, 9278649, 9278653</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FluMist Quadrivalent, 2017-2018 Formula Nasal Spray</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003817 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003817">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010311"/>
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        <rdfs:subClassOf>
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            <owl:Restriction>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003817</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1946980</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>792416</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003818 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003818">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003818</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4522494</rdfs:comment>
        <rdfs:comment>RXAUI: 9278618</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza A virus A/Slovenia/2903/2015 (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003819 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003819">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003819</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1946981</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003560>influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>792417</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003820 -->

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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003820</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2054182</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003818"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:hasDbXref>CUI: C4719703</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 10329701</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T116, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flumist Quadrivalent 2018-2019 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003821 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2054177</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4719701</rdfs:comment>
        <rdfs:comment>RXAUI: 10329696</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza B virus B/Colorado/06/2017 antigen</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003822 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003822">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003822</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <obo:VO_0003198>2054271</obo:VO_0003198>
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        <obo:VO_0003560>influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003823 -->

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        <obo:VO_0003198>2054273</obo:VO_0003198>
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        <obo:VO_0010151>35200284</obo:VO_0010151>
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        <oboInOwl:hasDbXref>RXAUI: 10329904</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0003824 -->

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        <rdfs:subClassOf>
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        <obo:IAO_0000118>FluMist Quadrivalent, Live Attenuated, 2018-2019 Formula Nasal Spray</obo:IAO_0000118>
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        <obo:VO_0003198>2054274</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray [Flumist Quadrivalent 2018-2019]</obo:VO_0003560>
        <obo:VO_0005279>FluMist Quadrivalent, Live Attenuated, 2018-2019 Formula Nasal Spray</obo:VO_0005279>
        <obo:VO_0010151>35200285</obo:VO_0010151>
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        <oboInOwl:hasDbXref>CUI: C4719751</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 10329907, 10329905, 10329906</oboInOwl:hasDbXref>
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        <rdfs:label>FluMist Quadrivalent, 2018-2019 Formula Nasal Spray</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003825 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003826 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003827 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003828 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003829 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003830 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003831 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Havrix, Hepatitis A Vaccine (Inactivated), (Pediatric Dose) 0.5 ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003832 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0010151>529685</obo:VO_0010151>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Havrix, Hepatitis A Vaccine (Inactivated), (Adult Dose) 1 ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003833 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0003834 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003835 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003836 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003837 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003841 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003842 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003845 -->

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        <rdfs:label>Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003846 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ipol Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003847 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003848 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0005279>Ipol (poliovirus vaccine inactivated, type 1 (Mahoney) 40 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 8 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 32 UNT/ML per 0.5 ML) Injectable Suspension</obo:VO_0005279>
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        <rdfs:label>IPOL vaccine Injectable Solution</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003849 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003850 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018838"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003850</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1187511</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3241253</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3848865</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhim VI Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003851 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003851">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000104"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003855"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003851</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003855"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/807223</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>807223</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML [Typhim VI]</obo:VO_0003560>
        <obo:VO_0010151>19132274</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2365227</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2863816</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML [Typhim VI]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003852 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003852">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003850"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003852</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>807225</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI]</obo:VO_0003560>
        <obo:VO_0005279>Typhim Vi, Typhoid Vi Polysaccharide Vaccine Injectable Solution</obo:VO_0005279>
        <obo:VO_0010151>19132275</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
        <oboInOwl:hasDbXref>CUI: C0711001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7251850, 2863819, 2863818</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhim Vi Injectable Solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003853 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003853">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003850"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003853</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>1486495</obo:VO_0003198>
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        <obo:VO_0003560>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Prefilled Syringe [Typhim VI]</obo:VO_0003560>
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        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C3701103</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 5937066</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhim VI Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003854 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003854">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003854</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1486496</obo:VO_0003198>
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        <obo:VO_0005279>Typhim VI 25 MCG per 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>44785110</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C0980908</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7252822, 5937069, 5937068, 5937067</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhim Vi 0.5 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003855 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003855">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003849"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003855</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>807220</obo:VO_0003198>
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        <obo:VO_0003560>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML</obo:VO_0003560>
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        <oboInOwl:hasDbXref>CUI: C2365225</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2863813</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003856 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003856">
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003856</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1361664</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1361664</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.025 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>43011517</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C3528060</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 5037103</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003857 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003857">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010448"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003857</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/830464</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>830464</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <obo:VO_0003560>rabies virus vaccine wistar strain PM-1503-3M (human), inactivated</obo:VO_0003560>
        <obo:VO_0010151>544505</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2586803</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 5026921</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003858 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003858">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003857"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003858</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/830465</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>830465</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <obo:VO_0003560>rabies virus vaccine wistar strain PM-1503-3M (human), inactivated 2.5 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>19133405</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2586804</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 5027213</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003859 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003859">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000063"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003859</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C4047087</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7255368</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Imovax Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003860 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003860">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000063"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003860</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1659731</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <obo:VO_0003560>rabies virus vaccine wistar strain PM-1503-3M (human), inactivated 2.5 UNT/ML [Imovax]</obo:VO_0003560>
        <obo:VO_0010151>46275644</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C4046958</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7255366</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML [Imovax]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003861 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003861">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003859"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003861</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:IAO_0000118>Imovax Rabies, Wistar Rabies Virus Strain PM-1503-3M (Human) 2.5 UNT per 1 ML Injection</obo:IAO_0000118>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/830470</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
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        <oboInOwl:hasDbXref>CUI: C0711018</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7253451, 7250938, 7255369, 7255370</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>1 ML Imovax 2.5 UNT/ML Injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003862 -->

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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003862</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>830457</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <obo:VO_0003560>rabies virus vaccine flury-lep strain</obo:VO_0003560>
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        <oboInOwl:hasDbXref>CUI: C2586798</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2939884</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabies virus vaccine flury-lep strain</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003863 -->

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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003863</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>830458</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <obo:VO_0003560>rabies virus vaccine flury-lep strain 2.5 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>19133401</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2586799</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2939885</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabies virus vaccine flury-lep strain 2.5 UNT/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003864 -->

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            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003864</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3231586</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3844818</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RabAvert Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003865 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003865">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000094"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003865</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003863"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>830461</obo:VO_0003198>
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        <oboInOwl:hasDbXref>CUI: C2586802</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2939888</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabies virus vaccine flury-lep strain 2.5 UNT/ML [RabAvert]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003866 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0010151>19133404</obo:VO_0010151>
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        <oboInOwl:hasDbXref>CUI: C0711019</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7253136, 7250934, 7252193, 7252192</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>1 ML RabAvert 2.5 UNT/ML Injection</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003867 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003867</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>RXAUI: 3837729</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hiberix Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003868 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003868</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003870"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1300809</obo:VO_0003198>
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    <!-- http://purl.obolibrary.org/obo/VO_0003869 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003870 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003871 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003872 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003874 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003875 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003876 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003877 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003878 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003879 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003880 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003882 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003884 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003885 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003886 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003887 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Flublok 2015-2016 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003888 -->

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        <obo:VO_0003560>influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Flublok 2015-2016]</obo:VO_0003560>
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    <!-- http://purl.obolibrary.org/obo/VO_0003889 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003890 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003891 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003892 -->

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        <obo:VO_0003560>influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML [Flublok 2016-2017]</obo:VO_0003560>
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    <!-- http://purl.obolibrary.org/obo/VO_0003893 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003894 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003895 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003896 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003897 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003898 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003904 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003905 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003906 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003907 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003908 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003908</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>2050374</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <obo:VO_0003560>influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>35200021</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003909 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <obo:VO_0003198>2050375</obo:VO_0003198>
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        <obo:VO_0003560>influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>35200022</obo:VO_0010151>
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        <rdfs:label>influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003910 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003910</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>FLUAD 2015-2016 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003911 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Fluad 2016-2017 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003912 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003913 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004281"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010431"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003602"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003713"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010412"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018960"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003913</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2050759</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003601"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003602"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003713"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:hasDbXref>CUI: C4719165</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 10290487</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T116, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluad 2018-2019 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003914">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015086"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003914</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1723997</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4059934</rdfs:comment>
        <rdfs:comment>RXAUI: 7710856</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>influenza B virus B/Brisbane/9/2014 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003915 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003915">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010308"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003915</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1724000</obo:VO_0003198>
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        <obo:VO_0003560>influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>35606410</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003916 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003916">
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003916</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>CUI: C4060278</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7710866</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FLUAD 2015-2016 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003917 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003917</metadata:prefixIRI>
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        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003473"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003915"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1724011</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1724011</obo:VO_0003198>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML / influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML [FLUAD 2015-2016]</obo:VO_0003560>
        <obo:VO_0010151>35606415</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C4060159</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7710874</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML / influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML [FLUAD 2015-2016]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003918 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003918">
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003918</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>1724004</obo:VO_0003198>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [FLUAD 2015-2016]</obo:VO_0003560>
        <obo:VO_0010151>35606412</obo:VO_0010151>
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        <oboInOwl:hasDbXref>RXAUI: 7710865</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FLUAD 2015-2016 vaccine Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003919 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003919</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1724012</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
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        <obo:VO_0003560>0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML / influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML Prefilled Syringe [FLUAD 2015-2016]</obo:VO_0003560>
        <obo:VO_0005279>FLUAD 2015-2016 Formula Influenza Virus Vaccine 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>35606416</obo:VO_0010151>
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        <oboInOwl:hasDbXref>CUI: C4059806</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 7710870, 7710875, 7716409</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FLUAD 2015-2016 vaccine 0.5 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003920 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003920">
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003920</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>CUI: C4271737</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8236921</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluad 2016-2017 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003921 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003921</metadata:prefixIRI>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003922 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003922</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Fluad 2016-2017 vaccine Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003923 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003924 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluad 2017-2018 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003925 -->

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        <obo:VO_0003560>influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Fluad 2017-2018]</obo:VO_0003560>
        <obo:VO_0010151>1593898</obo:VO_0010151>
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    <!-- http://purl.obolibrary.org/obo/VO_0003926 -->

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        <rdfs:label>Fluad 2017-2018 vaccine Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003927 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003928 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003928</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluad 2018-2019 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003929 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003929</metadata:prefixIRI>
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        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003714"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>2050760</obo:VO_0003198>
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        <obo:VO_0003560>influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML [Fluad 2018-2019]</obo:VO_0003560>
        <obo:VO_0010151>35200044</obo:VO_0010151>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML [Fluad 2018-2019]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003930 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003560>influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluad 2018-2019]</obo:VO_0003560>
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        <rdfs:label>Fluad 2018-2019 vaccine Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003931 -->

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        <rdfs:label>Fluad 2018-2019 vaccine 0.5 ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003932 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Gardasil Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003933 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003934 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003935 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003936 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003937 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003938 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003938</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/798265</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>798265</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <obo:VO_0003560>L1 protein, human papillomavirus type 16 vaccine 0.08 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>529113</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344294</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851343</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>L1 protein, Human papillomavirus type 16 Vaccine 0.08 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003939 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003939">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003300"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003939</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/798269</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>798269</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <obo:VO_0003560>L1 protein, human papillomavirus type 6 vaccine 0.04 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>529117</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344298</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851347</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>L1 protein, Human papillomavirus type 6 Vaccine 0.04 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003940 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003940">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003303"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003940</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1301885</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:hasDbXref>CUI: C2724165</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 4627784</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T116, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003941 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003941">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003302"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003941</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:hasDbXref>CUI: C2724167</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 4627786</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T116, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003942 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003942">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003942</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1301886</obo:VO_0003198>
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        <obo:VO_0003560>human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>42873274</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2725255</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 4627785</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003943 -->

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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003943</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1301888</obo:VO_0003198>
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        <oboInOwl:hasDbXref>CUI: C3474821</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003944 -->

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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003944</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3221549</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3832040</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Cervarix Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003945 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003945</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003942"/>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003943"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1301890</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <obo:VO_0003560>human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML / human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML [Cervarix]</obo:VO_0003560>
        <obo:VO_0010151>42873276</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2725256</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 4627789</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML / Human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML [Cervarix]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003946 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003946</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>867488</obo:VO_0003198>
        <obo:VO_0003560>L1 protein, human papillomavirus type 16 vaccine / L1 protein, human papillomavirus type 18 vaccine Prefilled Syringe [Cervarix]</obo:VO_0003560>
        <obo:VO_0010151>40167172</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C2723809</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CERVARIX Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003947 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0005279>Cervarix Human Papillomavirus bivalent (types 16 and 18) vaccine, recombinant 0.5 ML Prefilled Syringe</obo:VO_0005279>
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        <oboInOwl:hasDbXref>CUI: C2724157</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3266660, 4627790, 7236130</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CERVARIX 0.5 ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003948 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus vaccine, inactivated</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003949 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003949</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003950 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0003951 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003951</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1167200</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3221394</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3838660</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ixiaro Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003952 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003952">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0011558"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003950"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015421"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003952</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0003950"/>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1300782</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1300782</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <obo:VO_0003560>Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML [Ixiaro]</obo:VO_0003560>
        <obo:VO_0010151>42873199</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2682871</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 4626261</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML [Ixiaro]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003953 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003953">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003951"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0018618"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015421"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003953</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/845531</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>845531</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <obo:VO_0003560>Japanese encephalitis virus vaccine, inactivated Prefilled Syringe [Ixiaro]</obo:VO_0003560>
        <obo:VO_0010151>40159359</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C2682872</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2963104</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ixiaro (Japanese Encephalitis Vaccine, Inactivated, Adsorbed) Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003954 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003954">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003953"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015421"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003954</metadata:prefixIRI>
        <obo:IAO_0000118>Ixiaro (Japanese Encephalitis Vaccine, Inactivated, Adsorbed) 0.012 MG/ML 0.5 ML Prefilled Syringe</obo:IAO_0000118>
        <obo:IAO_0000118>Ixiaro 6 MCG per 0.5 ML Prefilled Syringe</obo:IAO_0000118>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1300783</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1300783</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <obo:VO_0003560>0.5 ML Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML Prefilled Syringe [Ixiaro]</obo:VO_0003560>
        <obo:VO_0005279>Ixiaro (Japanese Encephalitis Vaccine, Inactivated, Adsorbed) 0.012 MG/ML 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>42873439</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C2682873</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 6833047, 4626263, 2984288, 4626262, 2994485</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Ixiaro 0.012 MG/ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003955 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003955">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000919"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003955</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1812935</obo:IAO_0000119>
        <obo:VO_0003198>1812935</obo:VO_0003198>
        <obo:VO_0003560>Vibrio cholerae CVD 103-HGR strain live antigen</obo:VO_0003560>
        <obo:VO_0010151>1718154</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C4291328</rdfs:comment>
        <rdfs:comment>RXAUI: 8262960</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>vibrio cholerae CVD 103-HGR strain live antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003956 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003956">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003956</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0020289"/>
        <rdfs:label>obsolete vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003957 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003957">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003082"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0019097"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003957</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1812950</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0019097"/>
        <oboInOwl:hasDbXref>CUI: C4291505</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8262971</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaxchora Oral Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003958 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003958">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000064"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015416"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003958</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1172748</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3226798</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3838385</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Infanrix Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003959 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003959">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003284"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010453"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003959</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/854932</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>854932</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <obo:VO_0003560>Streptococcus pneumoniae type 10A capsular polysaccharide antigen</obo:VO_0003560>
        <obo:VO_0005279>pneumococcal capsular polysaccharide type 10A vaccine</obo:VO_0005279>
        <obo:VO_0010151>40163668</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 10A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003960 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003960">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000919"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003960</metadata:prefixIRI>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis vaccine antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003961 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003961">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001047"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011157"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003961</metadata:prefixIRI>
        <obo:IAO_0000115>replication defective simian adenoviral vector expressing KH, a self-cleaving polyprotein comprising L. donovani KMP-11 and HASPB</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5712</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/28498840</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0001047"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011157"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5712</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ChAd63-KH vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003962 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003962">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003957"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020292"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0018844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003962</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1812948</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0018844"/>
        <oboInOwl:hasDbXref>CUI: C4291477</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8262969</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaxchora Oral Suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003963 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003963">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003962"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0018844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003963</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1812951</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1812951</obo:VO_0003198>
        <obo:VO_0003560>Vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML Oral Suspension [Vaxchora]</obo:VO_0003560>
        <obo:VO_0005279>Vaxchora 12000000 UNT/ML Oral Suspension</obo:VO_0005279>
        <obo:VO_0010151>1718165</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0018844"/>
        <oboInOwl:hasDbXref>CUI: C4271028</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8262973, 8262974, 8262972</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaxchora 1,200,000,000 UNT per 100 ML Oral Suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003964 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003964">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003964</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1812947</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0020290"/>
        <rdfs:label>obsolete vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML [Vaxchora]</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003965 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003965">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019071"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003965</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2050058</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C4718905</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 9712930</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Heplisav-B Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003966 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003966">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003965"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019071"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003966</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2050058</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2050058</obo:VO_0003198>
        <obo:VO_0003560>hepatitis B surface antigen vaccine Prefilled Syringe [Heplisav-B]</obo:VO_0003560>
        <obo:VO_0010151>35200003</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C4718905</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 10287780</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HEPLISAV-B Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003967 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003967">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019071"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003967</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>0.5 ML Heplisav-B 0.04 MG/ML Prefilled Syringe</obo:IAO_0000118>
        <obo:IAO_0000118>HEPLISAV-B 20 MCG in 0.5 ML Prefilled Syringe</obo:IAO_0000118>
        <obo:IAO_0000118>Heplisav-B 0.04 MG/ML per 0.5 ML Prefilled Syringe</obo:IAO_0000118>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/2050059</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2050059</obo:VO_0003198>
        <obo:VO_0003560>0.5 ML hepatitis B surface antigen vaccine 0.04 MG/ML Prefilled Syringe [Heplisav-B]</obo:VO_0003560>
        <obo:VO_0005279>0.5 ML Heplisav-B 0.04 MG/ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>35201909</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C4553167</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 10287788, 10287789, 10287781, 10287783, 10287782</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HEPLISAV-B 20 MCG per 0.5 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003968 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003968">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003152"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003230"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019071"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003968</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
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        <obo:VO_0003198>1994349</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003560>hepatitis B surface antigen vaccine 0.04 MG/ML [Heplisav-B]</obo:VO_0003560>
        <obo:VO_0010151>793517</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C4541386</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 9712928</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B Surface Antigen Vaccine 0.04 MG/ML [Heplisav-B]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003969 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0003969">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015014"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003969</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:hasDbXref>CUI: C2346335</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 5027208</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003970 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0003970</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1184583</obo:IAO_0000119>
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        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3238386</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3843263</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pentacel Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0003971 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003987 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003988 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003989 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003990 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003991 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003995 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003996 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003997 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0003998 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004000 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004001 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004002 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001093"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004003</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=826</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0001093"/>
        <obo:VO_0001818>826</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies recombinant vector vaccine encoding gp50 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010905"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004004</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BoNT/C</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=91</obo:IAO_0000119>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010905"/>
        <obo:VO_0001818>91</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BoNT/C vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011203"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004005</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae CbpA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=787</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011203"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>787</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae CbpA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011193"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004006</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae ClpP protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=789</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011193"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>789</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae ClpP protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004007</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae PspA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=795</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011204"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>795</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae PspA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004008">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011199"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004008</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae SrtA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=798</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011199"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>798</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae SrtA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001065"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011191"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004009</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>N. caninum NcPDI Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=937</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011191"/>
        <obo:VO_0001818>937</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum NcPDI protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004010">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001065"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011202"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004010</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>N. caninum NcDG1 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=944</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011202"/>
        <obo:VO_0001818>944</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum NcDG1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011186"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004011</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>N. meningitidis ExbB Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=947</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011186"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>947</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis ExbB protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004012">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004012</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>N. meningitidis LctP Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=948</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011185"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>948</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis LctP protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011184"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004013</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>N. meningitidis NspA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=956</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011184"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>956</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis NspA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011182"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004014</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>N. miningitidis TBP2 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=957</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011182"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>957</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neisseria miningitidis TBP2 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004015">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011120"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004015</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=998</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011120"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>998</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding HA from influenza A virus (A/Hong Kong/1/68(H3N2))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011121"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004016</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=999</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011121"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>999</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding HA from influenza A virus (A/environment/Hong Kong/156/1997(H5N1))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011126"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004017</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1003</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011126"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1003</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus HA protein vaccine (influenza A virus (A/Yamagata/120/1986(H1N1)))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011127"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004018</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1004</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011127"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1004</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus HA protein vaccine (influenza A virus (A/Fukuoka/C29/85(H3N2)))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011129"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004019</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1005</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011129"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1005</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding HA from influenza B virus (B/Ibaraki/2/85)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011140"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004020</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1012</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011140"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1012</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding HA from influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004021">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011302"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004021</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1014</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011302"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1014</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding HA from influenza A virus (A/equine/Kentucky/1/1981(H3N8))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011152"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004022</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani GRP-78 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1029</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011152"/>
        <obo:VO_0001818>1029</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani GRP-78 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004023 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004023">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011155"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004023</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani Beta-tubulin Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1031</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011155"/>
        <obo:VO_0001818>1031</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani Beta-tubulin protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004024">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001230"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_160"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004024</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. pallidum GlpQ Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1069</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012399"/>
        <obo:VO_0001818>1069</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_160"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Treponema pallidum GlpQ protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004025 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004025">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001230"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012400"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_160"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004025</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. pallidum TmpB Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1070</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012400"/>
        <obo:VO_0001818>1070</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_160"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Treponema pallidum TmpB protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001230"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012401"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_160"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004026</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. pallidum Tp92 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1071</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012401"/>
        <obo:VO_0001818>1071</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_160"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Treponema pallidum Tp92 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000764"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012387"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004027</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. burgdorferi DbpA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1072</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012387"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
        <obo:VO_0001818>1072</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borrelia burgdorferi DbpA Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004028">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000764"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012384"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004028</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. burgdorferi OspA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1074</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012384"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
        <obo:VO_0001818>1074</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borrelia burgdorferi OspA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000764"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012385"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004029</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. burgdorferi OspB Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1075</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012385"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
        <obo:VO_0001818>1075</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borrelia burgdorferi OspB protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004030 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004030</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. burgdorferi OspC Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1076</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012386"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
        <obo:VO_0001818>1076</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borrelia burgdorferi OspC protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004031 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012388"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1639"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004031</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. monocytogenes DNA Vaccine encoding hly</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1077</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <obo:VO_0001818>1077</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1639"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Listeria monocytogenes DNA vaccine encoding hly</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004032 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002500"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004032</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1078</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>1078</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1639"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Listeria monocytogenes p60 Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011156"/>
            </owl:Restriction>
        </rdfs:subClassOf>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004033</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani Hsp70 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1109</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>1109</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani Hsp70 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004034</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1111</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>1111</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis FopB protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004035 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004035</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis DNA vaccine ESAT-6</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004036 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004036</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus DNA vaccine EBOV GP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004037 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004037</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Ebola virus EBOV NP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3577</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010859"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>3577</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus EBOV NP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004038">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012185"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012405"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000472"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004038</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Nontypeable H. influenzae NucA Protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=192</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012405"/>
        <obo:VO_0001818>192</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000472"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae NucA Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004039 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004039">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011242"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004039</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=822</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011242"/>
        <obo:VO_0001818>822</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Psuedorabies DNA vaccine encoding IE180 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011251"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004040</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=829</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011251"/>
        <obo:VO_0001818>829</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies Subunit gI protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004041">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011238"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004041</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=830</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011238"/>
        <obo:VO_0001818>830</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies Subunit gB protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004042">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000935"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011253"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_42890"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004042</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. neurona SAG1 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=835</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011253"/>
        <obo:VO_0001818>835</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_42890"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Sarcocystis neurona SAG1 Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004043">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000658"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011222"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004043</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=877</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011222"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
        <obo:VO_0001818>877</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotavirus VP6 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004044">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001231"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011279"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004044</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. major PSA-2 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1006</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011279"/>
        <obo:VO_0001818>1006</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania major PSA-2 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004045">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001231"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011277"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004045</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. major H2B Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1009</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011277"/>
        <obo:VO_0001818>1009</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania major H2B protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004046">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001231"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011278"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004046</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. major DNA Vaccine encoding Gp63</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1013</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011278"/>
        <obo:VO_0001818>1013</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania major DNA vaccine encoding Gp63</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002502"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012390"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004047</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. aureus ClfA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1082</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012390"/>
        <obo:VO_0001818>1082</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus ClfA Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004048 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004048">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002502"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012389"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004048</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. aureus CNA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1083</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012389"/>
        <obo:VO_0001818>1083</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus CNA Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004049">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002502"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004049</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. aureus FnbA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1084</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012392"/>
        <obo:VO_0001818>1084</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus FnbA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001375"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012393"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004050</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. agalactiae BPS Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1086</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012393"/>
        <obo:VO_0001818>1086</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus agalactiae BPS protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001375"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012403"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004051</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. agalactiae Rib Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1087</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012403"/>
        <obo:VO_0001818>1087</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus agalactiae Rib protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004052 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004052">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001375"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012402"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004052</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. agalactiae Sip Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1088</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012402"/>
        <obo:VO_0001818>1088</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus agalactiae Sip protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004053 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004053">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012397"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004053</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pyogenes Emm1 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1089</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012397"/>
        <obo:VO_0001818>1089</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pyogenes Emm1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012396"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004054</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pyogenes FbaA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1090</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012396"/>
        <obo:VO_0001818>1090</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pyogenes FbaA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004055">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012395"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004055</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pyogenes FBP54 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1091</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012395"/>
        <obo:VO_0001818>1091</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pyogenes FBP54 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004056 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004056">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004056</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pyogenes SfbI Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1092</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012394"/>
        <obo:VO_0001818>1092</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pyogenes SfbI protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004057 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004057">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002852"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004057</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pyogenes Sib35 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1093</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012398"/>
        <obo:VO_0001818>1093</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pyogenes Sib35 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004058 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004058">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004058</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M. tuberculosis DNA Vaccine encoding KatG</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1094</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012369"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>1094</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis DNA vaccine encoding KatG</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004059 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004059">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012373"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004059</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M. tuberculosis HBHA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1095</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012373"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>1095</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis HBHA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004060">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012181"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012377"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004060</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>H. pylori HspA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1097</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012377"/>
        <obo:VO_0001818>1097</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori HspA Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004061">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012181"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012378"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004061</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>H. pylori HspB Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1098</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012378"/>
        <obo:VO_0001818>1098</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori HspB Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004062">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012181"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012379"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004062</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>H. pylori GltA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1099</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012379"/>
        <obo:VO_0001818>1099</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori GltA Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004063 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004063">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012383"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004063</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae PhpA-79 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1100</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012383"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>1100</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae PhpA-79 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004064">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0012380"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004064</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>N. meningitidis TbpA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1101</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0012380"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>1101</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis TbpA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004065 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004065">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002513"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011225"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004065</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. berghei MSP1 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1105</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011225"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>1105</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium berghei MSP1 Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004066">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012159"/>
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            </owl:Restriction>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004066</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. infantum SMT Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1108</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011282"/>
        <obo:VO_0001818>1108</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania infantum SMT protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004067 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004067">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004067</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani HASPB1 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1028</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011162"/>
        <obo:VO_0001818>1028</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani HASPB1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004068 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004068">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004068</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae GtS Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=790</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>790</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae GtS protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004069 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004069">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004069</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae 6PGD Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=792</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>792</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae 6PGD protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004070 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004070">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004070</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae PiaA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=793</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>793</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae PiaA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004071 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004071">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004071</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae RASV synthesizing PsaA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=794</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>794</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae RASV synthesizing PsaA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004072 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004072">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004072</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=61</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>61</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus recombinant adenovirus vector vaccine ADV-GP/NP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004073">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004073</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>GP and NP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=71</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>71</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>GP and NP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004074 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004074">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004074</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BoNT/A(Hc)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=74</obo:IAO_0000119>
        <obo:VO_0001818>74</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BoNT/A(Hc) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004075">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004075</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>PBT</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=75</obo:IAO_0000119>
        <obo:VO_0001818>75</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PBT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004076</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BoNT/F(Hc)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=76</obo:IAO_0000119>
        <obo:VO_0001818>76</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BoNT/F(Hc) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004077 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004077">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004077</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BoNT/B(Hc)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=78</obo:IAO_0000119>
        <obo:VO_0001818>78</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BoNT/B(Hc) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004078 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004078">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004078</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>VRP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=82</obo:IAO_0000119>
        <obo:VO_0001818>82</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VRP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004079 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004079">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004079</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>V-LSN</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=83</obo:IAO_0000119>
        <obo:VO_0001818>83</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>V-LSN vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004080</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>V-LSG</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=84</obo:IAO_0000119>
        <obo:VO_0001818>84</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>V-LSG vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004081 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004081">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004081</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>V-LSG1 + V-LSG2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=85</obo:IAO_0000119>
        <obo:VO_0001818>85</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>V-LSG1 + V-LSG2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004082 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004082">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004082</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>V-LSG + V-LSN</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=86</obo:IAO_0000119>
        <obo:VO_0001818>86</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>V-LSG + V-LSN vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004083 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004083">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004083</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>V-LSG/N</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=87</obo:IAO_0000119>
        <obo:VO_0001818>87</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>V-LSG/N vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004084 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004084">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004084</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>HC of type C and D</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=88</obo:IAO_0000119>
        <obo:VO_0001818>88</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HC of type C and D vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004085 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004085">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004085</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ML29</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=89</obo:IAO_0000119>
        <obo:VO_0001818>89</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ML29 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004086 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004086">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004086</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>V-LSGPC</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=90</obo:IAO_0000119>
        <obo:VO_0001818>90</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>V-LSGPC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004087 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004087">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004087</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>VSV[Delta]G/LVGPC</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=92</obo:IAO_0000119>
        <obo:VO_0001818>92</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VSV[Delta]G/LVGPC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004088 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004088">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004088</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>YFV17D/LAS-GPC</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=93</obo:IAO_0000119>
        <obo:VO_0001818>93</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>YFV17D/LAS-GPC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004089 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004089">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004089</metadata:prefixIRI>
        <obo:IAO_0000115>Earlier investigational version of a smallpox vaccine developed by Acambis. It was part of the development process that led to the creation of ACAM2000. </obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ACAM1000</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ACAM1000 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004090 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004090">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004090</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CCSV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=97</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>97</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CCSV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004091 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004091">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004091</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>LC16m8</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=98</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>98</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>LC16m8 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004092 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004092">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004092</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>MVA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=99</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>99</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004093">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004093</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=100</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>100</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004094 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004094">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004094</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>dVV-L</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=101</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>101</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>dVV-L vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004095 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004095">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004095</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>IMV-EEV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=102</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>102</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IMV-EEV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004096">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004096</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=103</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>103</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Smallpox DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004097">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004097</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>MVA-BN</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=106</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>106</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVA-BN vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004098 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004098">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000651"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004098</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>LC16m0</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=107</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>107</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>LC16m0 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004099">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004099</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>pABFHc2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=108</obo:IAO_0000119>
        <obo:VO_0001818>108</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pABFHc2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001214"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004100</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>inactivated C. jejuni whole-cell (CWC)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=114</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001818>114</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated Campylobacter jejuni whole-cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004101">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004101</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>MBP fused on Campylobacter FlaA (MBP-FlaA)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=124</obo:IAO_0000119>
        <obo:VO_0001818>124</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MBP fused on Campylobacter FlaA (MBP-FlaA) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004102 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004102">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004102</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Recombinant DOBV nucleocapsid protein (rDOBV N)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=140</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>140</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant DOBV nucleocapsid protein (rDOBV N) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004103">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004103</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Truncated Recombinant DoBV Nucleocapsid Proteins (Dob-N rNp)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=141</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>141</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Truncated Recombinant DoBV Nucleocapsid Proteins (Dob-N rNp) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004104">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004104</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>VEE virus complex-specific monoclonal antibody</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=167</obo:IAO_0000119>
        <obo:VO_0001818>167</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VEE virus complex-specific monoclonal antibody vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004105 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004105</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=168</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001818>168</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Live attenuated vaccine TC-83</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004106 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004106">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004106</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>MVA85A prime and BCG boost</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:15196215</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=172</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>172</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVA85A prime and BCG boost vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004107 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004107">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003130"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004107</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BCG expressing MSP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=174</obo:IAO_0000119>
        <obo:VO_0001818>174</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG expressing MSP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004108 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004108">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004108</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Mtb72f fusion protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=175</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>175</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mtb72f fusion protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004109 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004109">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004109</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Recombinant RNA replicons from attenuated VEE virus</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=181</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001818>181</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant RNA replicons from attenuated VEE virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004110 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004110">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012185"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004110</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Nontypeable H. influenzae Outer Membrane Protein P1 vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=182</obo:IAO_0000119>
        <obo:VO_0001818>182</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000472"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae Outer Membrane Protein P1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004111 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004111">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004111</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chimeric SIN/VEE Virus SIN-83</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=183</obo:IAO_0000119>
        <obo:VO_0001818>183</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chimeric SIN/VEE Virus SIN-83 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004112 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004112">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004112</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=184</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>184</obo:VO_0001818>
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        <obo:VO_0005438>80</obo:VO_0005438>
        <obo:VO_0010151>40213253</obo:VO_0010151>
        <obo:VO_1000000>Venezuelan equine encephalitis, live, attenuated</obo:VO_1000000>
        <obo:VO_1000001>VEE, live</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Live attenuated VEE vaccines</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004113 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004113">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004113</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Live attenuated V3526 virus</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=185</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001818>185</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live attenuated V3526 virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004114 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004114">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004114</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Nontypeable H. influenzae outer membrane recombinant P4 vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=187</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>187</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000472"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae outer membrane recombinant P4 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004115 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004115">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012185"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004115</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Non-typeable H. influenzae dLOS-P6 vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=196</obo:IAO_0000119>
        <obo:VO_0001818>196</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000472"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nontypeable Haemophilus influenzae dLOS-P6 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004116 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004116">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004116</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Defective adenovirus expressing VEEV E2 glycoprotein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=197</obo:IAO_0000119>
        <obo:VO_0001818>197</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>defective adenovirus expressing VEEV E2 glycoprotein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004117 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004117">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004914"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004117</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Marburg virus-like particles</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=216</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <obo:VO_0001818>216</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg virus-like particles vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004118 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004118">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004118</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Adenovirus vectors expressing Marburg virus glycoprotein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=217</obo:IAO_0000119>
        <obo:VO_0001818>217</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Adenovirus vectors expressing Marburg virus glycoprotein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004119</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=218</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>218</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine encoding ANDV glycoproteins</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004120</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chimaeric HBV core particles carrying Puumala virus nucleocapsid protein fragments</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=219</obo:IAO_0000119>
        <obo:VO_0001818>219</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chimaeric HBV core particles carrying Puumala virus nucleocapsid protein fragments vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004121">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004121</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=220</obo:IAO_0000119>
        <obo:VO_0001818>220</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avirulent Salmonella vaccine strain carrying C. jejuni cjaA gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004122 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004122">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004122</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BCG auxotroph expressing HIV-1 clade immunogen</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=224</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>224</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG auxotroph expressing HIV-1 clade immunogen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004123 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004123">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004123</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M. tuberculosis DNA vaccine pAK4-sod</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=225</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>225</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis DNA vaccine pAK4-sod</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004124 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004124">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004124</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>deltaphoP/Q S. typhimurium strains expressing PEB1-ss</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=226</obo:IAO_0000119>
        <obo:VO_0001818>226</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>deltaphoP/Q Salmonella typhimurium strains expressing PEB1-ss vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004125 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004125">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004125</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Recombinant VEE Replicons expressing MBGV GP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=227</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>227</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant VEE Replicons expressing MBGV GP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004126 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004126">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004126</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Recombinant VEE Replicons expressing MBGV NP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=228</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>228</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant VEE Replicons expressing MBGV NP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004127 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004127">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004127</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Irradiated MBGV antigen</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=229</obo:IAO_0000119>
        <obo:VO_0001818>229</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Irradiated MBGV antigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004128 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004128">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004128</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Marburg virus glycoprotein expressed by baculovirus recombinants</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=230</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>230</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg virus glycoprotein expressed by baculovirus recombinants vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004129 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004129">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000463"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004129</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Q-VAX</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=237</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
        <obo:VO_0001818>237</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Q-VAX vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004130 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004130">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004130</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=238</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>238</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Multivalent DNA vaccine for B. anthracis, Ebola virus, Marburg virus, and VEE virus</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004131 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004131">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000463"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004131</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M-44</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=240</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
        <obo:VO_0001818>240</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>M-44 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004132 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004132">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000463"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004132</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chloroform-methanol residue (CMR)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=241</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
        <obo:VO_0001818>241</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chloroform-methanol residue (CMR) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004133 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004133">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000463"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004133</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P1-HspB (fusion of protein 1 and heat-shock protein B)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=242</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
        <obo:VO_0001818>242</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>P1-HspB (fusion of protein 1 and heat-shock protein B) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004134 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004134">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000463"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004134</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Coxevac</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=243</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
        <obo:VO_0001818>243</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coxevac vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004135 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004135">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000463"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004135</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chlamyvax FQ</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=244</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11100"/>
        <obo:VO_0001818>244</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_777"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamyvax FQ vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004136 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004136">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004136</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=245</obo:IAO_0000119>
        <obo:VO_0001818>245</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VSV-based vaccine expressing MBGV GP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004137 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004137">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004137</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Heterologous MARV Protein VLP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=246</obo:IAO_0000119>
        <obo:VO_0001818>246</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>heterologous MARV protein VLP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004138 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004138">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004138</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CVD 909</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=250</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>250</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CVD 909 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004139 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004139">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004139</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CVD 915</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=253</obo:IAO_0000119>
        <obo:VO_0001818>253</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CVD 915 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004140 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004140">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004140</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=255</obo:IAO_0000119>
        <obo:VO_0001818>255</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Broilact Chick Salmonella vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004141 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004141">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004141</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Zoosaloral H.</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=256</obo:IAO_0000119>
        <obo:VO_0001818>256</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Zoosaloral H. vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004142 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004142">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004142</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Salmonella vacT</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=257</obo:IAO_0000119>
        <obo:VO_0001818>257</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella vacT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004143 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004143">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000680"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004143</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. flexneri 2a strain CVD 1205</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=261</obo:IAO_0000119>
        <obo:VO_0001818>261</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella flexneri 2a strain CVD 1205 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004144 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004144">
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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli heat-labile enterotoxin B-subunit (LB-T) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004145 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>shiga toxin 2 B subunit vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004146 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=296</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella ovis microparticle subunit vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004147 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004147</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Live, Attenuated Rifampin-Resistant Rough Mutants of Brucella melitensis</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=297</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        <obo:VO_0001818>297</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live, attenuated Rifampin-resistant rough mutants of Brucella melitensis vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004148 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004148</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=303</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <obo:VO_0001818>303</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine co-expressing A85A and caspase-3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004149 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004149</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Recombinant vaccinia A27L, D8L, and B5R Proteins with adjuvant MPL-TDM</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004150 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004150</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>killed vaccinia virus vaccine with adjuvant NanoEmulsion</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004151 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000123"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004151</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11089"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>yellow fever NS1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004152 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004152</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11089"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vP869 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004153 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004153</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella subunit vaccine encoding gI and gE glycoproteins</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004154 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004154</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=814</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0050175"/>
        <obo:VO_0001818>814</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>TBEV DNA vaccine encoding E protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004155 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004155">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004155</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=820</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>820</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseduorabies Subunit Glycoprotein C vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004156 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004156">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004156</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=827</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>827</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies recombinant vector vaccine encoding gp50 and gII protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004157 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004157">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004157</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Y. pestis YscF Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=886</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>886</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis YscF protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004158 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004158">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004158</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Y. pestis DNA vaccine encoding dfF1 Protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=906</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>906</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis DNA vaccine encoding dfF1 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004159 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004159">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004159</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RASV expressing Y. pestis Psn</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=908</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>908</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RASV expressing Yersinia pestis Psn vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004160 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004160">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000658"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004160</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=914</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
        <obo:VO_0001818>914</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotavirus VP2/VP 6 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004161 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004161">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000658"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004161</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=917</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
        <obo:VO_0001818>917</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotavirus VP4/VP7 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004162">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002514"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004162</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. yoelii DNA vaccine encoding PyHEP17 Protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=927</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>927</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii DNA vaccine encoding PyHEP17 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004163 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004163">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001065"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004163</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>N. caninum DNA vaccine encoding NcSAG1 and NcSRS2, combined with recombinant NcSAG1 and NcSRS2 proteins</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=935</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>935</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum DNA vaccine encoding NcSAG1 and NcSRS2, combined with recombinant NcSAG1 and NcSRS2 Protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004164 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004164">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001065"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004164</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>N. caninum MIC10 and p24 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=946</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>946</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum MIC10 and p24 protein vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004165 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004165</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CCPS-P64kR</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=953</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>953</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CCPS-P64kR vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004166 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004166</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>C. botulinum DNA vaccine pSCARSA/BHc</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=983</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>983</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Clostridium botulinum DNA vaccine pSCARSA/BHc</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004167 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004167</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=991</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>991</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding HA of Equine influenza virus H3N8</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004168 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004168</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant vesicular stomatitis virus encoding HA from Influenza A virus (A/WSN/1933(H1N1)) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004169 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004169</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>995</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant baculovirus encoding HA from Influenza A virus (A/Puerto Rico/8/1934(H1N1)) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004170 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004170</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>996</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant vaccinia virus encoding HA from Influenza B virus (Strain B/England/222/82) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004171 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004171</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>1000</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania major DNA vaccine encoding LACKp24, TSA, LmSTI1 and CPa</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004172 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004172</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania major DNA vaccine encoding SP</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004173 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004173</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>pCAGGoptiHA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1002</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1002</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pCAGGoptiHA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004174 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004174">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004174</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BacHA derived from Influenza A virus (A/Indonesia/CDC669/2006(H5N1))</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1007</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1007</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BacHA derived from Influenza A virus (A/Indonesia/CDC669/2006(H5N1)) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004175 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004175">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004175</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1010</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1010</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Flagellin-based HA globular head fusion vaccine using HA protein from Influenza A virus (A/Viet Nam/1203/2004(H5N1))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004176 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004176">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001231"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004176</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. major H1 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1011</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1011</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania major H1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004177 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004177">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004177</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1015</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1015</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding M1 from influenza A virus (A/chicken/Henan/12/2004(H5N1))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004178">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004178</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>AdH5-FluA NP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1021</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1021</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AdH5-FluA NP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004179 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004179">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004179</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani LD31 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1030</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1030</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani LD31 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004180 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004180">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004180</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1032</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>1032</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania vaccine using recombinant L. tarentolae strain expressing A2 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000909"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5874"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004181</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. annulata Tams1 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1055</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1055</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5874"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Theileria annulata Tams1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000671"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004182</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. typhi DnaJ Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1056</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001818>1056</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella typhi DnaJ protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004183 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004183">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000671"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004183</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. typhi GroEL Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1057</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001818>1057</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella typhi GroEL protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004184">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004184</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1060</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1060</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella IroN protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004185">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004185</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1062</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>1062</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella DNA vaccine encoding SopB Protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004186 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004186">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004186</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. typimurium Vi4072</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1063</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1063</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella typimurium Vi4072 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004187 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004187">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000654"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004187</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1068</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
        <obo:VO_0001818>1068</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Measles Virus vaccine VEE/SIN-H</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004188 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004188">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000764"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004188</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. burgdorferi DbpA and OspA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1073</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
        <obo:VO_0001818>1073</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borrelia burgdorferi DbpA and OspA Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004189 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004189">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000393"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004189</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. aeruginosa DNA Vaccine encoding OprF</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1079</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>1079</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudomonas aeruginosa DNA vaccine encoding OprF</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004190 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004190">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000393"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004190</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. aeruginosa OprI Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1080</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1080</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudomonas aeruginosa OprI protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004191 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004191">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000393"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004191</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. aeruginosa PcrV Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1081</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1081</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudomonas aeruginosa PcrV protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004192">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002502"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004192</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. aureus DNA Vaccine encoding PBP2a Protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1085</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>1085</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus DNA vaccine encoding PBP2a Protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004193 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004193">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004193</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum LSA-3 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1096</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>1096</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum LSA-3 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004194">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004194</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1102</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>1102</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>P. chabaudi AMA1 Protein Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004195 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004195">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004195</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum CS expressed in irradiated P. berghei as Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1103</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>1103</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum CS expressed in irradiated  Plasmodium berghei vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004196 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004196">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004196</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum DNA Vaccine encoding EBA-175</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1104</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>1104</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum DNA vaccine encoding EBA-175</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004197 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004197">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012159"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004197</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>pcDNA3-LiP0</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1106</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1106</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pcDNA3-LiP0 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004198 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004198">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012159"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004198</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>VVr expressing L. infantum P36/LACK</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1107</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1107</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VVr expressing L. infantum P37/LACK vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004199 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004199">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012158"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5659"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004199</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. amazonensis CP Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1110</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1110</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5659"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania amazonensis CP Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004200 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004200">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001375"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004200</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. agalactiae BipA Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1112</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1112</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1311"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus agalactiae BipA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004201 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004201">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004201</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>J5dLPS/OMP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1118</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001818>1118</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>J5dLPS/OMP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004202 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004202">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012176"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004202</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum Tarp subunit vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1119</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>1119</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum Tarp subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004203 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004203">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004203</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>C. jejuni PorA protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1120</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>1120</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter jejuni PorA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004204 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004204">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004204</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum pfCelTos protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1121</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>1121</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum pfCelTos protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004205 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004205">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003995"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004205</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/806594</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>806594</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <obo:VO_0003560>acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Boostrix]</obo:VO_0003560>
        <obo:VO_0010151>40153533</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C2364909</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 5027374</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BOOSTRIX vaccine Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004206 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004206</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Boostrix (Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 8 MCG / Bordetella pertussis pertactin vaccine, inactivated 2.5 MCG / Bordetella pertussis toxoid vaccine, inactivated 8 MCG / diphtheria toxoid vaccine, inactivated 2.5 UNT / tetanus toxoid vaccine, inactivated 5 UNT) per 0.5 ML Prefilled Syringe</obo:IAO_0000118>
        <obo:IAO_0000118>Boostrix Tdap (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed) 0.5 ML Prefilled Syringe</obo:IAO_0000118>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1300370</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1300370</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <obo:VO_0003560>0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Boostrix]</obo:VO_0003560>
        <obo:VO_0010151>42800267</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:hasDbXref>CUI: C2364910</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 5027662, 7253757, 4625540, 4625564</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BOOSTRIX vaccine 0.5 ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004207 -->

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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004207</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1300365</obo:IAO_0000119>
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        <oboInOwl:hasDbXref>CUI: C3474172</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 4625526</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004208 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004208">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000919"/>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1368371</obo:IAO_0000119>
        <obo:VO_0003198>1368371</obo:VO_0003198>
        <obo:VO_0003560>Bacillus anthracis strain V770-NP1-R antigens</obo:VO_0003560>
        <obo:VO_0010151>46274593</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C3535682</rdfs:comment>
        <rdfs:comment>RXAUI: 5068281</rdfs:comment>
        <rdfs:comment>TUI: T116, T129, T121</rdfs:comment>
        <rdfs:label>BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004209 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004209</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2074</obo:IAO_0000119>
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        <obo:VO_0001818>2074</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10258"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ovine Ecthyma live virus vaccine by Colorado Serum Company CZ Veterinaria</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004210 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004210">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004210</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <obo:VO_0001818>2075</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10258"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ovine Ecthyma live virus vaccine by Texas Agricultural Experiment Station</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004211 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004211">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9788"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000701"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004211</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2149</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9788"/>
        <obo:VO_0001818>2149</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>West Nile Virus DNA Vaccine (USDA: 1995.D0)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004212 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004212">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000391"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001471"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001526"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007748"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000204"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004212</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2736</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2737</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9612"/>
        <obo:VO_0001818>2736</obo:VO_0001818>
        <obo:VO_0001818>2737</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_149595"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_171"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine Parainfluenza Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 47A9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004213 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004213">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004213</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0019406"/>
        <rdfs:label>obsolete BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS 0.1 MG/ML</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004214 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004214">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001456"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001802"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_738"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004214</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2979</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2980</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2981</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2979</obo:VO_0001818>
        <obo:VO_0001818>2980</obo:VO_0001818>
        <obo:VO_0001818>2981</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_738"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine-Erysipelothrix Rhusiopathiae-Haemophilus Parasuis Bacterin (USDA: 49V9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004215 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004215">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000014"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015374"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004215</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1174360</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3228377</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3830942</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Biothrax Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004216 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004216">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004216</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/1799963</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0019407"/>
        <rdfs:label>obsolete BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS 0.1 MG/ML [Biothrax]</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004217 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004217">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000563"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001802"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003535"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_738"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004217</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2982</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=2983</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>2982</obo:VO_0001818>
        <obo:VO_0001818>2983</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_738"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Porcine Reproductive &amp; Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine-Haemophilus Parasuis Bacterin (USDA: 49Q9.20)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004218 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004218">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004215"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0018596"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015374"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004218</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/832681</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015072"/>
        <oboInOwl:hasDbXref>CUI: C2608510</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2943547</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Biothrax Injectable Suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004219 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004219">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004219</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii DNA vaccine encoding MIC8</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3038</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3038</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine encoding MIC8</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004220 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004220">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002502"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004220</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. aureus IsdB subunit vaccine (V710)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3039</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>3039</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus IsdB subunit vaccine (V710)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004221 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004221">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000620"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004221</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. multocida rOmpH Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3040</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3040</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_747"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pasteurella multocida rOmpH vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004222 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004222">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001527"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_260963"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004222</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3046</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001818>3046</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_260963"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Inactivated PMV-3 vaccine with Specol</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004223 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004223">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004223</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. anthracis rPA Vaccine with Rehydragel HPA adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3047</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>3047</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis rPA vaccine with Rehydragel HPA adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004224">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000658"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004224</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3048</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
        <obo:VO_0001818>3048</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotavirus Chimeric VP6 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004225 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004225">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004225</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3050</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>3050</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BHV1 gD subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004226 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004226">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001501"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004226</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3051</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001818>3051</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11099"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BVDV Inactivated vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004227 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004227">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005488"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004227</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:9725239</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3053</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/369</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3053</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>cancer vaccine using E7 protein of human papillomavirus 16 and Algammulin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004228 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004228">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005488"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004228</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:10931134</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9725239</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3054</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/370</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001818>3054</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>cancer vaccine using E7 protein of human papillomavirus 16 and Quil-A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004229">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001125"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5804"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004229</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>E. maxima oocysts with Arlacel A vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3056</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3056</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5804"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria maxima oocysts with Arlacel A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004230 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004230">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000640"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004230</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Tetanus Toxoid with Calcium Phosphate</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3057</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001818>3057</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tetanus Toxoid vaccine with Calcium Phosphate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004231 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004231">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000640"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004231</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Tetanus Toxoid with Stearyl Tyrosine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3058</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001818>3058</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tetanus Toxoid vaccine with Stearyl Tyrosine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004232">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004232</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>V3 VLPs with Gamma inulin adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3059</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>3059</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>V3 VLPs vaccine with Gamma inulin adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004233 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004233">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004233</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>gp120 recominant with GMDP adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3061</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>3061</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>gp120 recominant vaccine with GMDP adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004234">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004234</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>gp120 recominant with MDP adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3062</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>3062</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>gp120 recominant vaccine with MDP adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004235 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004235">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004235</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rHA with IL-1Beta adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3063</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3063</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rHA with IL-1Beta adjuvant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004236">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004236</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rHA with IL-2 adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3064</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3064</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rHA with IL-2 adjuvant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004237 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004237">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004237</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rHA with IL-7 adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3065</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3065</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rHA with IL-7 adjuvant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004238 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004238">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004238</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3067</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>3067</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>gp140, Gag and Tat protein vaccine with MF59</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004239 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004239">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000644"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004239</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3068</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001818>3068</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HBsAg liposomal MTP-PE vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004240 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004240">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001207"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_813"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004240</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3069</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3069</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_813"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>synthetic OMP1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004241</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani Recombinant Ld-Gamma-GCS in NIV system Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3070</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>3070</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani recombinant Ld-Gamma-GCS in NIV system vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004242</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3071</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3071</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated HIV-2 vaccine with PMMA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004243 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004243">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004243</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum MSP4 with AFCo1 Adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3072</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>3072</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum MSP4 vaccine with AFCo1 adjuvant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004244</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Inactivated split Mem 71 Virus with SPT adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3073</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3073</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Inactivated split Mem 71 Virus with SPT adjuvant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004245">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005426"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004245</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3074</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>3074</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Recombinant Colorectal cancer antigen GA733 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004246 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004246">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010148"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004246</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3076</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>3076</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Anthrax vaccine adsorbed with Squalene adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004247 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004247">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004247</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3077</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3077</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Group A streptococcal recombinant fusion peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004248 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004248">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004248</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3078</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3078</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant NY-ESO-1 protein vaccine adjuvanted with imiquimod</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004249 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004249">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004249</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3080</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3080</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mutagrip vaccine with P40 adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004250">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005488"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004250</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:28706878</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3081</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/241</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001818>3081</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>attenuated Listeria expressing cancer antigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004251 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004251">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000644"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004251</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3082</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001818>3082</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant S gene Hepatitis B vaccine with rIFN-gamma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004252 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004252">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004252</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Y. pestis F1 antigen Vaccine with Flagellin</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3083</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3083</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis F1 antigen vaccine with Flagellin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004253 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004253">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004253</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3084</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3084</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated H1N1(2009) vaccine with AF03 adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004254 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004254">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004254</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3085</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3085</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant NY-ESO-1 ISCOMATRIX vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004255</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Recombinant PA with Poly(I:C) Adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3086</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>3086</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant PA vaccine with Poly(I:C) adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004256 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004256">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83334"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004256</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3087</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>3087</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83334"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant Tir protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004257 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004257">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012176"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004257</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum PmpG-1, PmpE/F-2, and MOMP Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3089</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3089</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum PmpG-1, PmpE/F-2, and MOMP protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004258 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004258">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004258</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3091</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>3091</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>synthetic MUC1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004259 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004259">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004259</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3092</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>3092</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV-2 DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004260 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004260">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000644"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004260</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Hepatitis B surface antigen (HBsAg) with JVRS-1000</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3093</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001818>3093</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B surface antigen (HBsAg) with JVRS-1000 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004261">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001220"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004261</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3094</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001818>3094</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>live TC-83 VEE vaccine with DHEA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004262 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004262">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004262</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000933"/>
        <rdfs:label>obsolete E. coli CS3 in PLGA microspheres</rdfs:label>
        <rdfs:seeAlso>violinID: 3095</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004263 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004263">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004263</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3096</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>3096</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVA/IL-15/5Mtb vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004264 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004264">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004264</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3097</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>3097</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rgp120 HIV vaccine with immunoliposomes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004265 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004265">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004265</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3098</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>3098</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal polysaccharide conjugate vaccine serotype 1 (PNC-1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004266 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004266">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004266</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3099</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5966</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3099</obo:VO_0001818>
        <obo:VO_0001818>5966</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>LEISH-F1+MPL-SE vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004267 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004267">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012168"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004267</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3100</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>3100</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HSV glycoproteins subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004268 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004268">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004268</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>HIV-1 gp120 with mCT E112K</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3101</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3101</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV-1 gp120 with mCT E112K vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004269 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004269">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004269</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum MSA-2 subunit vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3103</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>3103</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum MSA-2 subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004270 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004270">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004270</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. anthracis PA protein Vaccine with TMDP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3104</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>3104</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis PA protein vaccine with TMDP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004271 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004271">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002514"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004271</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. yoelii TyCS-VLP Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3105</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>3105</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii TyCS-VLP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004272">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004272</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3106</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3106</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pVAX-P1 DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004273">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004273</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3107</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3107</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>YopE(67-77) protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004274 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004274">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV recombinant gp160 protein vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004275 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3110</obo:VO_0001818>
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        <rdfs:label>human apo B-100 peptide-2 protein vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004276 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3111</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MDA-modified human apo B-100 peptide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004277 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004277</metadata:prefixIRI>
        <obo:IAO_0000115>A mucR mutant has a significantly reduced degree of colonization in mice and protects against wild type B. melitensis 16M</obo:IAO_0000115>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis mucR mutant vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004278 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004278</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tick-borne Encephalitis Virus C protein mutant vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004279 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis mce-2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004280 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Aflunov vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004281 -->

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        <rdfs:label>Fluad vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004282 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004282</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Focetria</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3287</obo:IAO_0000119>
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        <obo:VO_0001818>3287</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Focetria vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004283 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004283</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3288</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3288</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus S19 vjbR mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004284 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004284</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3289</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3289</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10497"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>African Swine Fever Virus 9GL mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004285 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000108"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004285</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Recombinant B. abortus CobB protein with CFA/IFA adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3292</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3292</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant Brucella abortus CobB protein vaccine with CFA/IFA adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004286 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000108"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004286</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Recombinant B. abortus AsnC protein with CFA/IFA adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3293</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3293</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant Brucella abortus AsnC protein vaccine with CFA/IFA adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004287 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004287</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3294</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>M2 mutant from influenza A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004288 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004288</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3296</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis mce-3 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004289 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004289</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3299</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine Respiratory Syncytial Virus recombinant vector vaccine BHVl/BRSVG encoding the G protein</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004290 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004290</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine BacPAKHA encoding EqfKY HA</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004291 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine p188 encoding H7</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004292 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pCMV/Hl encoding H1</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004293 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004293</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3305</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pCMV/H7</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004294 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004294</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pIRES/HA encoding HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004295 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pIRES/NA expressing NA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004296 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004296</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pIRES/HA/IL-2 expressing HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004297 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004297</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pIRES/NA/IL-2 encoding NA</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004298 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004298</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3310</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3310</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pIRES/HA/GM-CSF encoding HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004299 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004299</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3311</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3311</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pIRES/NA/GM-CSF encoding NA</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004300 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004300</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3312</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3312</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pIRES/HA/IL-12p35 + pIRES/NA/IL-12p40</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004301 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004301</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3316</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pRSV-NP encoding the coding sequence from influenza virus A/PR/8/34.</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004302 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004302</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3318</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pHA/NP147-155 encoding NP147-155</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004303 -->

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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004303</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3320</obo:IAO_0000119>
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        <obo:VO_0001818>3320</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pBK-SFV-NP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004304 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004304</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3322</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pBK-SFV-HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004305 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004305</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3324</obo:IAO_0000119>
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        <obo:VO_0001818>3324</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine HA-DNA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004306 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3327</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine d1TTFC-NP encoding NP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004307 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004307</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3330</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3330</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine A/NP</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004308 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004308</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3331</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine NP DNA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004309 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine HA DNA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004310 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004310</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine NA-DNA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004311 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004311</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3338</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine H5 DNA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004312 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004312</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3342</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine pSAG1-ROP2-SAG2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004313 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004313</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine pcDNA3.1-SAG1-ROP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004314 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004314</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Y. pestis DNA vaccine F1-V DNA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3344</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3344</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis DNA vaccine F1-V DNA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004315 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004315">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004315</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3349</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>3349</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 DNA vaccine pRSVgIV</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004316 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004316">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004316</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3350</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>3350</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 recombinant vector vaccine BHVl/BRSVG</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004317 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004317">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004317</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3357</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3357</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 DNA vaccine pMASIAtgB encoding a truncated, secreted form of gB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004318 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004318</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3359</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3359</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 recombinant vector vaccine rLaSota/gDFL encoding gD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004319</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3360</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3360</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 recombinant vector vaccine rLaSota/gDF encoding gD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004320">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001213"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004320</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3366</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3366</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12110"/>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Foot and mouth disease DNA vaccine pWRMHX encoding a minimal self-cleaving ribozyme</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004321 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004321">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004321</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3369</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IHNV DNA vaccine pCMV4-G</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004322 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8022"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004322</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3370</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3370</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8022"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IHNV DNA vaccine pCMV4-N encoding the nucleoprotein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004323 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004323">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003062"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10366"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004323</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3372</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3372</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10366"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Murine cytomegalovirus DNA vaccine pcDNA-89 encoding pp89</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004324 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004324">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004324</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3373</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3373</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle disease virus DNA vaccine pCAGF encoding the F protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004325 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004325">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001802"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004325</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3374</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3374</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PRRSV DNA vaccine GST-ORF5 encoding GP5</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004326 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004326">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004326</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3375</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>3375</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies virus DNA vaccine pSG5rab.gp</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004327 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004327">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003044"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052303"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004327</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3376</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3376</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052303"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lymphocytic choriomeningitis virus DNA vaccine pCMV-NP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004328 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004328">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004328</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3379</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001818>3379</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus DNA vaccine VlJns-Ll encoding L1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004329 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004329">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004329</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3380</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3380</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus DNA vaccine Pe7(pcDNA3-Sig/sE7/LAMP) encoding E7</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004330 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004330">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004330</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3383</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3383</obo:VO_0001818>
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        <rdfs:label>Human papillomavirus DNA vaccine pC16-L1 encoding L1</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004331 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3384</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001818>3384</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus DNA vaccine CRT/E7 DNA</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004332 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004332</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3388</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3388</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus DNA vaccine E7IR</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004333 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004333</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3389</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3389</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus DNA vaccine E7SH DNA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004334 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004334</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3392</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus DNA vaccine GP DNA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004335 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004335</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Ebola virus recombinant rAD-GP encoding GP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3393</obo:IAO_0000119>
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        <obo:VO_0001818>3393</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus recombinant rAD-GP encoding GP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004336 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004336</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Ebola virus recombinant VSVΔG-GP encoding GP</obo:IAO_0000118>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3394</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus recombinant VSVΔG-GP encoding GP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004337 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004337">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004337</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3395</obo:IAO_0000119>
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        <obo:VO_0001818>3395</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus recombinant vector vaccine EBO7 encoding GP from SEBOV and ZEBOV</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004338 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004338</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3396</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VHSV DNA vaccine pCMV-vhsG encoding glycoprotein G</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004339 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3397</obo:IAO_0000119>
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        <obo:VO_0001818>3397</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VHSV DNA vaccine pCMV-vhsN encoding nucleocapsid protein N and glycoprotein G</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004340 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3398</obo:IAO_0000119>
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        <obo:VO_0001818>3398</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Classical swine fever virus DNA vaccine pCI-gp55</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004341 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004341</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human cytomegalovirus DNA vaccine VCL-CB01 encoding phosphoprotein 65 and gB</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004342 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004342</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV DNA vaccine Ad26/Ad5HVR48 encoding HIV or SIV env or gag</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004343 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SIV DNA vaccine pVacc4 encoding env from mac239</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004344 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004344</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3439</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV DNA vaccine SHIV-89.6 DNA (DNA/89.6)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004345 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004345</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3449</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3449</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV DNA vaccine pCMN160</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004346 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004346</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3468</obo:IAO_0000119>
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        <obo:VO_0001818>3468</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SIV DNA vaccine pSIVgag and pmacIL-15 encoding SIV core protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004347 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004347</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3478</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV recombinant vector vaccine MVA-gag encoding gag</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004348 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <obo:VO_0001818>3481</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV DNA vaccine pHIS-SHIV-B</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004349 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3485</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV DNA vaccine SIVmac239 Gag-Pol-Nef and mock Env with rAd5 boost</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004350 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3491</obo:IAO_0000119>
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        <obo:VO_0001818>3491</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV recombinant vector vaccine MVA.HIVA encoding env and rev</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004351 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3497</obo:IAO_0000119>
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        <obo:VO_0001818>3497</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HIV DNA vaccine VlJns-tPA-gp120</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004352 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B DNA vaccine PLGA-CTAB-DNA encoding the small envelope gene</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004353 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Duck hepatitis B DNA vaccine pcDNA I-S encoding small S proteins</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004354 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004354</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3519</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B DNA vaccine pRc/CMV-HBs(S) encoding HBsAg</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004355 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004355</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pDNA encoding M2 and NP</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004356 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004356</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M. tuberculosis DNA vaccine pcDNA3.1+/Ag85A DNA encoding Ag85A</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3522</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3522</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis DNA vaccine pcDNA3.1+/Ag85A DNA encoding Ag85A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004357 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004357</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3524</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001818>3524</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B DNA vaccine pS encoding major envelope proteins</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004358 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004358</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3525</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3525</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B DNA vaccine pCMV-HBs encoding HBsAg</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004359 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004359</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3528</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B DNA vaccine pCEA/HBsAg encoding CEA and HBsAg</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004360 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004360</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3533</obo:IAO_0000119>
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        <obo:VO_0001818>3533</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B DNA vaccine pCMV-S2.S encoding the HBV(ayw Strain) envelope protein.</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004361 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3538</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3538</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12066"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coxsackievirus DNA vaccine pCMV/VPl encoding VP1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004362 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004362</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3540</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis DNA vaccine encoding Ag85B, MPT64 and MPT83</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004363 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004363</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3546</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis DNA vaccine (containing the ESAT-6, MPT-64, MPT-83, and KatG constructs)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004364 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis DNA vaccine DNAAg85A encoding a single immunogenic M.tb Ag</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004365 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3548</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus DNA vaccine gD-2 encoding gD</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004366 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004366</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus DNA vaccine Delta-gB-2 encoding gB</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004367 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus DNA vaccine ICP-27 DNA encoding ICP-27</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004368 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004368</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus DNA vaccine gB-DNA encoding gB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004369 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004369</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus DNA vaccine gBDNA encoding gB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004370 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004370</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus DNA vaccine encoding gD and gB from HSV-2 strain Curtis</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004371 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004371</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3555</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>3555</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies virus DNA vaccine pCMV-intA-rabies encoding glycoprotein G</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004372 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004372</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3556</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>3556</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies virus DNA vaccine encoding the ERA glycoprotein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004373 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004373">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004373</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3557</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3557</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania major DNA vaccine KMP-11</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004374 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004374">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004374</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine encoding TSA-1, ASP-1, ASP-2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3558</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3558</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine encoding TSA-1, ASP-1, ASP-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004375 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004375">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004375</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine encoding ASP-2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3559</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3559</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine encoding ASP-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004376 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004376">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004376</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine pUB-ASP-2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3560</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3560</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine pUB-ASP-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004377 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004377</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine pTS encoding T. cruzi antigens</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3561</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3561</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine pTS encoding Trypanosoma cruzi antigens</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004378 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004378</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3565</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3565</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lassa fever virus recombinant vector vaccine V-LSG encoding the glycoprotein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004379 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004379</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3567</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3567</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lassa fever virus recombinant vector vaccine V-LSG/N encoding the glycoprotein and the nucleoprotein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004380 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lassa fever virus recombinant vector vaccine YFV17D/LASV-GPC encoding the glycoprotein precursor</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004381 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3574</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus recombinant vector vaccine pVSVXN2-Delta-G/ZEBOVsGP encoding GP</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004382 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3579</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus recombinant adenovirus vaccine AdC7-ZGP encoding GP</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004383 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus recombinant vector vaccine Ad-CMVZGP encoding the glycoprotein</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004384 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus recombinant vector vaccine Ad-CAGoptZGP encoding the envelope glycoprotein</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004385 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004385</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0001818>3591</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus DNA vaccine DNA/rAd5 encoding ZEBOV and SEBOV antigens</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004386 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004386</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis DNA vaccine PA</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004387 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004387</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3594</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3594</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9986"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg virus DNA vaccine MARV GP encoding GP</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004388 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004388</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3596</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>3596</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg virus recombinant vector vaccine CAdVax-Panfilo</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004389 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004389</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3598</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3598</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg virus DNA prime/boost vaccine DNA/rAd5-GP encoding GP from strain Angola</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004390 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004390</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3599</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3599</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg virus DNA vaccine DNA-GP encoding GP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004391 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004391</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3600</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3600</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg virus recombinant vector vaccine MBGV GP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004392 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001225"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004392</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus DNA vaccine pcDNA3.1-p39-L7/L12 encoding p39-L7/L12 fusion protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3605</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3605</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus DNA vaccine pcDNA3.1-p39-L7/L12 encoding p39-L7/L12 fusion protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004393 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001225"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004393</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus DNA vaccine pcDNA3-SOD encoding Cu-Zn SOD</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3607</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3607</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus DNA vaccine pcDNA3-SOD encoding Cu-Zn SOD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004394 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004394</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis DNA vaccine pCI-Omp31</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004395 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004395</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3613</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis DNA vaccine pCIBLSOmp31 encoding BLSOmp31 (fusion protein)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004396 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004396">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004396</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis DNA vaccine p-Omp25</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3615</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>3615</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis DNA vaccine p-Omp25</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004397 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004397">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000709"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004397</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. melitensis DNA vaccine p-ialB</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3616</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>3616</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29459"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella melitensis DNA vaccine p-ialB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004398 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004398">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004398</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3617</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001818>3617</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Lymphoma DNA vaccine V-Alpha-V-Beta-V-Beta-FrC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004399 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004399">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004399</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum recombinant vector vaccine MVA.ME-TRAP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3628</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>3628</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum recombinant vector vaccine MVA.ME-TRAP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004400 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004400">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005499"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004400</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous dendritic cell vaccine with potential immunostimulatory activity. Dendritic cells harvested from a prostate cancer patient are transfected with the mRNA encoding for prostate specific antigen (PSA), a tumor marker secreted by prostatic epithelial and ductal cells. When reintroduced back to the patient, these PSA RNA pulsed autologous dendritic cells may elicit a cytotoxic T-cell (CTL) response against PSA-positive prostate cancer cells. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3643</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/175</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3643</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Glypican-3-derived peptide vaccine for human hepatocellular carcinoma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004401 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004401">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002837"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10114"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004401</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3647</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_417"/>
        <obo:VO_0001818>3647</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10114"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>EAE DNA vaccine pZZ/MBP68-85 encoding MBP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004402 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004402">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004402</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3649</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_417"/>
        <obo:VO_0001818>3649</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>EAU DNA vaccine IRBP-DNA encoding IRBP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004403 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004403">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9351"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004403</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3652</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9351"/>
        <obo:VO_0001818>3652</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Autoimmune diabetes DNA vaccine pND2-SGAD55</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004404 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004404</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3653</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9351"/>
        <obo:VO_0001818>3653</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Autoimmune diabetes DNA vaccine pCMV-1/rGAD65 encoding GAD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004405 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004405</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3655</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9351"/>
        <obo:VO_0001818>3655</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Autoimmune diabetes DNA vaccine pND2-GAD65-BAX encoding GAD and BAX</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004406 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004406</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3656</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9351"/>
        <obo:VO_0001818>3656</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Insulin-dependent diabetes mellitus DNA vaccine JwGAD65 + IL-4</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004407 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004407">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004407</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3661</obo:IAO_0000119>
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        <obo:VO_0001818>3661</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Adjuvant arthritis DNA vaccine pCMV3.65 encoding HSP65</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004408 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004408</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3662</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3662</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pristane-induced arthritis DNA vaccine DNA-hsp65 encoding Mycobacterium leprae 65-kDa heat shock protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004409 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004409</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3663</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_848"/>
        <obo:VO_0001818>3663</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Adjuvant arthritis DNA vaccine CII encoding type II collagen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004410 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004410">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004410</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3664</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_848"/>
        <obo:VO_0001818>3664</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10114"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Adjuvant arthritis DNA vaccine pcDNA-CCOL2A1 encoding type II collagen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004411 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004411">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004411</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3665</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3665</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus DNA vaccine pSIN-gB encoding gB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004412 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004412</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3666</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3666</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus DNA vaccine pCI-gB encoding gB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004413 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004413</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. burgdorferi DNA vaccine pCMV-ZS7/TPA encoding OspC from Borrelia burgdorferi sensu lato</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3669</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
        <obo:VO_0001818>3669</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borrelia burgdorferi DNA vaccine pCMV-ZS7/TPA encoding OspC from Borrelia burgdorferi sensu lato</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004414 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004414</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3672</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3672</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>C. tetani DNA vaccine pcDNA3tetC encoding fragment C</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004415 -->

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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004415</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3673</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>West Nile virus DNA vaccine pCBWN encoding prM and E</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004416 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004416</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3677</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis DNA vaccine pDNA encoding PA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004417 -->

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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004417</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3678</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3678</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis DNA vaccine LF pDNA encoding LF</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004418 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000906"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004418</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>E. acervulina DNA vaccine 3-1E</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3681</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3681</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5800"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria acervulina DNA vaccine 3-1E</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004419 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004419">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002455"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004419</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3682</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980915"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hirame rhabdovirus DNA vaccine pHRV-G encoding HIRRV and VHSV G protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004420 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004420">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012165"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8022"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004420</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3687</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3687</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8022"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IHNV DNA vaccine pCDNA-G encoding G</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004421 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004421">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004421</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3689</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3689</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VEE virus DNA vaccine VEEV IA/B parent encoding structural genes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004422 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004422">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004422</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3690</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>3690</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VEE virus recombinant vector vaccine RAd/VEEV</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004423 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004423">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004423</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3691</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>3691</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VEE virus recombinant vector vaccine RAd/VEEV#2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004424 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004424">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001499"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004424</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3692</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>3692</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11036"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VEE virus recombinant vector vaccine RAd/VEEV#3 encoding TC-83</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004425 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004425">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004425</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15879128</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3695</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/316</obo:IAO_0000233>
        <obo:OGG_0000000006>8132375</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3695</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Fragment C from tetanus toxin</rdfs:comment>
        <rdfs:label>Cancer DNA vaccine p.DOM-AH1 encoding fragment C</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004426 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004426">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004426</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:18273615</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3696</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/378</obo:IAO_0000233>
        <obo:OGG_0000000006>21423</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001818>3696</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E2A</rdfs:comment>
        <rdfs:label>Carcinoma DNA vaccine pVAX/E2A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004427 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004427">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004427</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:12384547</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3698</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/292</obo:IAO_0000233>
        <obo:OGG_0000000006>1945467</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3698</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Immunoglobulin</rdfs:comment>
        <rdfs:label>B-cell lymphoma DNA vaccine VCL-1642.XXX encoding a chimeric immunoglobulin molecule onsisting of tumor-specific variable (Id) regions</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004428 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004428">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004428</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:12231517</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3699</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/387</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:OGG_0000000006>128168861</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3699</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>CEA</rdfs:comment>
        <rdfs:comment>Gene name: S</rdfs:comment>
        <rdfs:label>Colorectal cancer DNA vaccine pCEA/HBsAg encoding carcinoembryonic antigen and hepatitis B surface antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004429 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004429">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004429</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:12496961</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3700</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/294</obo:IAO_0000233>
        <obo:OGG_0000000006>22178</obo:OGG_0000000006>
        <obo:OGG_0000000006>7306</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3700</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TYRP1</rdfs:comment>
        <rdfs:comment>Gene name: Tyrp1</rdfs:comment>
        <rdfs:label>B16 melanoma DNA vaccine pSin-hTRP-1 encoding TRP-1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004430 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004430">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004430</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:12496961</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3701</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/293</obo:IAO_0000233>
        <obo:OGG_0000000006>22178</obo:OGG_0000000006>
        <obo:OGG_0000000006>7306</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3701</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TYRP1</rdfs:comment>
        <rdfs:comment>Gene name: Tyrp1</rdfs:comment>
        <rdfs:label>B16 melanoma DNA vaccine pCMV-hTRP-1 encoding TRP-1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004431 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004431">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004431</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Melanoma DNA vaccine TA2M(TM) encoding tyrosinase peptides</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3705</obo:IAO_0000119>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3705</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Melanoma DNA vaccine TA2M encoding tyrosinase peptides</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004432 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004432">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004432</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3713</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/518</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3713</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Survivin</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine VR-S8/VR-IL2/AD-S8 encoding survivin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004433 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004433">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004433</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3717</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/512</obo:IAO_0000233>
        <obo:OGG_0000000006>2922</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3717</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GRP</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine pCR3.1-VS-HSP65-TP-GRP6-M2 encoding 6 tandem repeats of GRP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004434 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004434">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004434</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3718</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/514</obo:IAO_0000233>
        <obo:OGG_0000000006>12981</obo:OGG_0000000006>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3718</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA1</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine pNL3-MAGE-1-GM</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004435 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004435">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004435</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3719</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/513</obo:IAO_0000233>
        <obo:OGG_0000000006>12981</obo:OGG_0000000006>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3719</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA1</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine pN4a-MAGE-1-GM</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004436 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004436">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004436</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3720</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/516</obo:IAO_0000233>
        <obo:OGG_0000000006>84004</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3720</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Mcam</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine SINCp c-muMUC18 encoding MCAM/MUC18</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004437 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004437">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004437</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3723</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/485</obo:IAO_0000233>
        <obo:OGG_0000000006>17829</obo:OGG_0000000006>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3723</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:comment>Gene name: Muc1</rdfs:comment>
        <rdfs:label>Lung metastasis DNA vaccine pCEP4-MUC1 encoding MUC1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004438 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004438">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004438</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3724</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/511</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3724</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine hugp100 encoding gp100</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004439 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004439">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004439</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3726</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/519</obo:IAO_0000233>
        <obo:OGG_0000000006>20431</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3726</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Pmel17</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine VR1012/mPmel17</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004440 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004440">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004440</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3727</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/509</obo:IAO_0000233>
        <obo:OGG_0000000006>1067130</obo:OGG_0000000006>
        <obo:OGG_0000000006>1638</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3727</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HUMGP 75</rdfs:comment>
        <rdfs:comment>Gene name: TRP-2</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine gp75 DNA encoding melanosomal membrane glycoproteins, gp75 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004441 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004441">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004441</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3728</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/521</obo:IAO_0000233>
        <obo:OGG_0000000006>22178</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3728</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TRP-1</rdfs:comment>
        <rdfs:label>Melanoma recombinant vector vaccine rVVmTRP-1 encoding TRP-1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004442 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004442">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004442</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3729</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/510</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3729</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine hTRP2 encoding TRP-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004443 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004443">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004443</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3730</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/515</obo:IAO_0000233>
        <obo:OGG_0000000006>104042</obo:OGG_0000000006>
        <obo:OGG_0000000006>55118</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3730</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Trp2</rdfs:comment>
        <rdfs:comment>Gene name: Ubiquitin</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine pUB-TRP-2 encoding a fusion protein linking murine ubiquitin (UB) to the N-terminus of the full-length mTRP-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004444 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004444">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_769"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004444</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3731</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_769"/>
        <obo:VO_0001818>3731</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Neuroblastoma DNA vaccine HuDsec</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004445 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004445">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004445</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3736</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001818>3736</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Prostate cancer DNA vaccine pcDNA3-STEAP encoding six-transmembrane epithelial antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004446 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004446</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3737</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>3737</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Prostate cancer DNA vaccine hPSMAt encoding PSMA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004447 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004447</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Prostate cancer DNA vaccine rPSMAt encoding PSMA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004448 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004448</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Prostate cancer DNA vaccine pVax-PSA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004449 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004449</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Prostate cancer DNA vaccine psig-3P-Fc encoding 3P(hPSM, hPAP, or hPSA)-Fc fusion protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004450 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004450</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3744</obo:VO_0001818>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Prostate cancer DNA vaccine PSCA-HSP encoding PSCA and HSP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004451 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004451</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Prostate cancer DNA vaccine encoding PSCA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004452 -->

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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3746</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001818>3746</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Prostate cancer DNA vaccine pmPSCA encoding PSCA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004453 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004453</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii DNA vaccine pMIC3i encoding the complete MIC3-ORF (RH(ERP) strain)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3754</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3754</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine pMIC3i encoding the complete MIC3-ORF (RH(ERP) strain)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004454 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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            </owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004454</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii DNA vaccine pVR1020-GRA1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3755</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3755</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine pVR1020-GRA1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004455 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004455">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004455</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii DNA vaccine T.g.HSP70</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3756</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3756</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine T.g.HSP70</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004456">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004456</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chinese S. japonicum DNA vaccine pCMV-Sjc97 encoding paramyosin</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3757</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3757</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chinese Schistosoma japonicum DNA vaccine pCMV-Sjc97 encoding paramyosin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004457 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004457">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004457</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chinese S. japonicum DNA vaccine pVAX/SjFABP encoding FABP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3758</obo:IAO_0000119>
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        <obo:VO_0001818>3758</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chinese Schistosoma japonicum DNA vaccine pVAX/SjFABP encoding FABP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004458 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004458">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004458</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chinese S. japonicum DNA vaccine SjCTPI</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3760</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3760</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chinese Schistosoma japonicum DNA vaccine SjCTPI</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004459 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004459">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004459</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chinese S. japonicum DNA vaccine SjCTPI-Hsp70</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3761</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3761</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chinese Schistosoma japonicum DNA vaccine SjCTPI-Hsp70</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004460 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004460">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001229"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004460</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chinese S. japonicum DNA vaccine pVIVO2-IL12-Sj23 encoding Sj23 and IL-12</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3762</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3762</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chinese Schistosoma japonicum DNA vaccine pVIVO2-IL12-Sj23 encoding Sj23 and IL-12</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004461 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004461">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003046"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004461</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. mansoni DNA vaccine Sm23-pcDNA encoding Sm23</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3763</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3763</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Schistosoma mansoni DNA vaccine Sm23-pcDNA encoding Sm23</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004462 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004462">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003046"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004462</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. mansoni DNA vaccine pcDNA/CTSOD encoding SOD</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3764</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3764</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Schistosoma mansoni DNA vaccine pcDNA/CTSOD encoding SOD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004463 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004463">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003046"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004463</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. mansoni DNA vaccine pcDNA/GPXbb encoding glutathione-S-peroxidase, GPX</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3765</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3765</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Schistosoma mansoni DNA vaccine pcDNA/GPXbb encoding glutathione-S-peroxidase, GPX</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004464 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004464">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003046"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004464</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. mansoni DNA vaccine Sm-p80-pcDNA3 encoding the large subunit of S. mansoni calpain</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3767</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3767</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6183"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Schistosoma mansoni DNA vaccine Sm-p80-pcDNA3 encoding the large subunit of Schistosoma mansoni calpain</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004465 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004465">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004465</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3768</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/520</obo:IAO_0000233>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3768</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:label>Melanoma DNA vaccine xenogeneic DNA encoding murine tyrosinase</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004466 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004466">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000725"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004466</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3770</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
        <obo:VO_0001818>3770</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue virus DNA vaccine sA encoding prM and E from Dengue Virus 4</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004467 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004467">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000725"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004467</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3771</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
        <obo:VO_0001818>3771</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue virus DNA vaccine sB encoding E</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004468 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004468">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000725"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004468</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3772</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
        <obo:VO_0001818>3772</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue virus DNA vaccine sC encoding prM and E</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004469 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004469">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000725"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0004470 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <rdfs:label>Dengue virus DNA vaccine D1ME encoding prM and E</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004471 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3779</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue virus DNA vaccine pE1D2 encoding E from Dengue Virus 2 strain New Guinea C</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004472 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <rdfs:label>Dengue virus DNA vaccine pcTPANS1 encoding NS1 fused to the tissue plasminogen activator signal sequence</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004473 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <rdfs:label>Dengue virus DNA vaccine 1040D2MEL encoding dengue-2 prM-E-LAMP chimeric protein</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004474 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <rdfs:label>Dengue virus DNA vaccine p1012D2ME encoding prM and E from DEN 2 New Guinea C strain</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004475 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <rdfs:label>Human papillomavirus DNA vaccine hCRTE6E7L2 DNA encoding CRT linked to E6, E7 and L2</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004476 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0004477 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0004478 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0004479 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0004480 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0004481 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0004482 -->

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        <rdfs:label>Vaccinia virus DNA vaccine A33R from strain IHD-J</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004483 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaccinia virus DNA vaccine B5R</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004484 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3810</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001818>3810</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaccinia virus DNA vaccine pWRG/L1R</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004485 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004485">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004485</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3814</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3814</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaccinia virus DNA vaccine 4pox</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004486 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004486">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004486</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3815</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3815</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaccinia virus DNA vaccine wtD8L</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004487 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004487</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaccinia virus DNA vaccine tPA-D8L</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004488 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004488</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3822</obo:IAO_0000119>
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        <obo:VO_0001818>3822</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VEE virus DNA vaccine encoding 26S</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004489 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004489</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3823</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3823</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>WEE virus DNA vaccine pVHX-6 encoding 26S</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004490 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004490">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004490</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3829</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3829</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VEE virus DNA vaccine pSTU-TRDF encoding VEEV E3-E2-6K</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004491 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004491">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003043"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004491</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3830</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Sindbis virus DNA vaccine encoding E2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004492 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004492">
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004492</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3831</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3831</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FeLV DNA vaccine gag/pol and env</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004493 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_504568"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004493</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3834</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3834</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11002"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_504568"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IPNV DNA vaccine pEGFP-N1-SegA and pEGFP-N1-VP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004494 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11287"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004494</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3836</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3836</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11287"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VHSV DNA vaccine pVHS-G encoding glycoproteins</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004495 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004495">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012165"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004495</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3837</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3837</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IHNV DNA vaccine pIHN-G encoding glycoproteins</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004496 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004496">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003058"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1781"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004496</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M. marinum pCMV-85A</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3838</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3838</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1781"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium marinum pCMV-85A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004497 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004497">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004497</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3839</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3839</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian influenza virus DNA vaccine pH5HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004498 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004498</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3840</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3840</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian influenza virus DNA vaccine pN1NA encoding N1 neuraminidase</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004499 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004499">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004499</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3841</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3841</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian influenza virus DNA vaccine pNP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004500 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004500">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004500</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3842</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3842</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pCMVH5HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004501 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004501</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3844</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3844</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine p-Beta-actinH7HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004502 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004502</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3845</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3845</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pCAGGoptiHA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004503 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004503">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004503</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3846</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>3846</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine pCAGGHA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004504 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004504">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000461"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004504</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3847</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0001818>3847</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian influenza DNA vaccine pCMV-M</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004505 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004505">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004505</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3848</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3848</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>avian influenza virus DNA vaccine pCMV-HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004506 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004506</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3849</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3849</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PRRSV DNA vaccine pCA-U-optiGP5</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004507 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004507">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004507</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3852</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3852</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PRRSV DNA vaccine pIRESorf5/IFN-Gamma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004508 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004508</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3853</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3853</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PRRSV DNA vaccine pIRESorf5/IL-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004509 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004509">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004509</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3854</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3854</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PRRSV DNA vaccine pIRESorf7/IL-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004510 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004510">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004510</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3857</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3857</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28344"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PRRSV DNA vaccine pCI-ORF5/ORF6</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004511 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004511">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001229"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004511</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chinese S. japonicum DNA vaccine SjC23-Hsp70</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3860</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3860</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chinese Schistosoma japonicum DNA vaccine SjC23-Hsp70</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004512 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004512">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004512</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Chinese S. japonicum DNA vaccine SjC23</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3861</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3861</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chinese Schistosoma japonicum DNA vaccine SjC23</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004513 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004513">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000764"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004513</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. burgdorferi DNA vaccine encoding strain B31 OspA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3863</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11729"/>
        <obo:VO_0001818>3863</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_139"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borrelia burgdorferi DNA vaccine encoding strain B31 OspA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004514 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004514">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004514</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3864</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3864</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine expressing the E2 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004515 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004515">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000611"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_738"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004515</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3865</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3865</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_738"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pCgap DNA vaccine encoding glyceraldehyde-3-phosphate dehydrogenase</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004516 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004516">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004516</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3867</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3867</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine expressing PspA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004517 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004517">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004517</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3868</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>3868</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PsaA DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004518 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004518">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004518</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3869</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3869</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>B16 melanoma DNA vaccine pSin-mTRP-1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004519 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004519">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012168"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004519</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3870</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3870</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes Simplex Virus Type 1 DNA Vaccine pRSC-gD-IL-21</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004520 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004520">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004520</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3871</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3871</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes Simplex Virus Type 1 DNA Vaccine encoding 5gP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004521 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004521">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004521</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3872</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3872</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes Simplex Virus 2 DNA Vaccine Vaxfectin-gD2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004522 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004522">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004522</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3873</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3873</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes Simplex Virus 2 DNA Vaccine encoding gD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004523 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004523">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012168"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004523</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3874</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3874</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes Simplex Virus 2 DNA Vaccine encoding gD with CD40L</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004524 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004524">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004524</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3876</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3876</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>classicals swine fever virus DNA vaccine pcDNA/E2 with TRIF</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004525 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004525">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001514"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38525"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004525</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3878</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8782"/>
        <obo:VO_0001818>3878</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38525"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avian pneumovirus DNA vaccine expressing the F gene</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004526 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004526">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003062"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10366"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004526</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3880</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3880</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10366"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Murine cytomegalovirus DNA vaccine pgM-pgN</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004527 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004527">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001125"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004527</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>E. maxima DNA vaccine pcDNA-Gam56</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3881</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3881</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5804"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria maxima DNA vaccine pcDNA-Gam56</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004528 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004528">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004528</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii DNA vaccine pVAX-TgMIC13</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3882</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3882</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine pVAX-TgMIC13</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004529 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004529</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3883</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3883</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12475"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis D DNA vaccine pcDNA3p27/Ad5F35p27</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004530 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004530">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004530</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. major DNA vaccine pcLACK + IL-22</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3884</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3884</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania major DNA vaccine pcLACK + IL-22</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004531 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004531">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004531</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii DNA vaccine ROP8-pVAX-1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3885</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3885</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine ROP8-pVAX-1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004532 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004532">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001385"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004532</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. cruzi DNA vaccine encoding TSA-1 and Tc24</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3886</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3886</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5693"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9615"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi DNA vaccine encoding TSA-1 and Tc24</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004533 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001497"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004533</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3887</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3887</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IBDV DNA vaccine pCAGoptiVP2/rVP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004534 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004534">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004534</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3888</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3888</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IBDV DNA vaccine pCAGVP243-IL-18</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004535 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004535">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001502"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004535</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3889</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3889</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IBV DNA vaccine pVAX1-16S1/M/N</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004536 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004536">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000620"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004536</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. multocida DNA vaccine pcDNA-OMPH + pcDNA-OMPA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3890</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3890</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pasteurella multocida DNA vaccine pcDNA-OMPH + pcDNA-OMPA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004537 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004537">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004537</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. multocida DNA vaccine pcDNA-OMPH/OMPA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3891</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3891</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pasteurella multocida DNA vaccine pcDNA-OMPH/OMPA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004538 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003061"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004538</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3892</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>3892</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_54315"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BVDV DNA vaccine encoding E2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004539 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004539">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004539</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>E. rhusiopathiae DNA vaccine pcD-ACSC</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3893</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3893</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1648"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Erysipelothrix rhusiopathiae DNA vaccine pcD-ACSC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004540 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004540">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002501"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1764"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004540</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M. avium DNA vaccine DNA-Av35/p2AIL12</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3894</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3894</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1764"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium avium DNA vaccine DNA-Av35/p2AIL12</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004541 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004541">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002502"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004541</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. aureus DNA vaccine pClfaSrtD13</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3895</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3895</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus DNA vaccine pClfaSrtD13</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004542 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004542">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004542</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. aureus DNA vaccine encoding Efb, FnbpA, ClfA, Cna</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3896</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3896</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1280"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus DNA vaccine encoding Efb, FnbpA, ClfA, Cna</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004543 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004543">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004543</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. anthracis DNA Vaccine expressing PA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3897</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3897</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis DNA vaccine expressing PA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004544 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004544">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004544</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>A. pleuropneumoniae DNA vaccine pcDNA-apxIA/pcDNA-apxIIA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3898</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3898</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Actinobacillus pleuropneumoniae DNA vaccine pcDNA-apxIA/pcDNA-apxIIA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004545 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004545">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004545</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3899</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3899</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Borrelia pertussis DNA vaccine pcDNA/S1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004546 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004546">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001225"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004546</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus DNA vaccine pVF278</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3900</obo:IAO_0000119>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>3900</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus DNA vaccine pVF278</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004547 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004547</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3902</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3902</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue virus DNA vaccine expressing prM/E protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004548 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004548</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3903</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3903</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue virus DNA vaccine D1ME-VRP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004549 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004549</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3904</obo:IAO_0000119>
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        <obo:VO_0001818>3904</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue virus DNA vaccine encoding NS1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004550 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004550</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3906</obo:IAO_0000119>
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        <obo:VO_0001818>3906</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Feline immunodeficiency virus recombinant vector vaccine FIV-Delta-RT</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004551 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004551</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3907</obo:IAO_0000119>
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        <obo:VO_0001818>3907</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Foot-and-Mouth Disease Virus DNA vaccine pSinCMV-Vac-MEG990</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004552 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004552</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3908</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3908</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Foot-and-Mouth Disease Virus Cationic Microparticle-coated DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004553 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004553</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3909</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3909</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FMDV DNA vaccine encoding P1 and non-structural proteins 2A, 3C, and 3D</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004554 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004554</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3910</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia trachomatis DNA vaccine pWRG7079::MOMP</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004555 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3911</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila pneumoniae DNA vaccine pHSP-61</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004556 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000118>E. tarda DNA vaccine pCE18</obo:IAO_0000118>
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        <obo:VO_0001818>3912</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Edwardsiella tarda DNA vaccine pCE18</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004557 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>E. tarda DNA vaccine pCE6</obo:IAO_0000118>
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        <obo:VO_0001818>3913</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Edwardsiella tarda DNA vaccine pCE6</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004558 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Edwardsiella tarda DNA vaccine pCEsa1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004559 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004559</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori DNA vaccine poipA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004560 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004560</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori DNA vaccine pcDNA3.2-hspA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004561 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3917</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori DNA vaccine pcDNA3.2-hspB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004562 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leptospira interrogans DNA vaccine ompL1-pcDNA3.1(+)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004563 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leptospira interrogans DNA vaccine pTARGET/ LigBrep</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004564 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0001818>3920</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SIV recombinant vector vaccine rAd5/rLCMV</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004565 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004565</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3921</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3921</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Laryngotracheitis DNA vaccine encoding gB</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004566 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004566</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3922</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3922</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10141"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg virus recombinant vector vaccine MBGV GP/MBGV NP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004567 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004567</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>H. rhabdovirus DNA Vaccine encoding N and G</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3923</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3923</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980915"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hirame rhabdovirus DNA vaccine encoding N and G</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004568 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004568</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3924</obo:IAO_0000119>
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        <obo:VO_0001818>3924</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine M2-DNA/M2-Ad</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004569 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004569</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3926</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis DNA vaccine P3A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004570 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004570</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. aeruginosa DNA vaccine pGACAG-OprF/OprI</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3927</obo:IAO_0000119>
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        <obo:VO_0001818>3927</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudomonas aeruginosa DNA vaccine pGACAG-OprF/OprI</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004571 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004571</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3928</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3928</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudomonas aeruginosa DNA vaccine pGACAG-PcrV</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004572 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004572</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000118>P. aeruginosa DNA vaccine pGACAG-OprF/OprI + pGACAG-PcrV + pGACAG-PilA</obo:IAO_0000118>
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        <obo:VO_0001818>3929</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pseudomonas aeruginosa DNA vaccine pGACAG-OprF/OprI + pGACAG-PcrV + pGACAG-PilA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004573 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004573</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Y. pestis DNA vaccine YscF-2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3930</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3930</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis DNA vaccine YscF-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004574 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004574</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3931</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>3931</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11246"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BRSV DNA vaccine VCL-Fb</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004575 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_691956"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004575</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3932</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3932</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_691956"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Duck hepatitis virus 1 DNA vaccine pSCA/VP1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004576 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004576">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004576</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3933</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3933</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hantavirus DNA vaccine pWRG/HTN-M</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004577 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004577</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3934</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3934</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RHDV DNA vaccine pcDNA-VP60</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004578 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012168"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004578</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3935</obo:IAO_0000119>
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        <obo:VO_0001818>3935</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HSV 2 DNA vaccine pVAX-HSV-2gD-HSP70</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004579 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002512"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004579</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3936</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3936</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HRSV DNA vaccine DRF-412</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004580 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004580">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004580</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3937</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3937</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HRSV DNA vaccine pND-G</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004581 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004581</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3938</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3938</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IBV DNA vaccine pVAX1-N</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004582 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004582</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3939</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3939</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IBV DNA vaccine pVAX-S1 with GM-CSF adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004583 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>H. rhabdovirus DNA Vaccine encoding G</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3940</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3940</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980915"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hirame rhabdovirus DNA vaccine encoding G</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004584 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004584</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3941</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3941</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Infectious Bronchitis virus DNA vaccine encoding S1, N, and M</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004585 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004585">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004585</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3942</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3942</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Infectious Bursal Disease virus DNA vaccine expressing VP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004586 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004586</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3943</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus DNA vaccine P-JEV</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004587 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004587</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3944</obo:IAO_0000119>
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        <obo:VO_0001818>3944</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus DNA vaccine pCJ-3/E encoding E</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004588 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3946</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3946</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>REV DNA vaccine VP22/gag and VP22/env</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004589 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004589</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. yoelii DNA vaccine pDIP/PyCSP. 1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3947</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3947</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii DNA vaccine pDIP/PyCSPlasmodium 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004590 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004590</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3948</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii DNA vaccine encoding PySSP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004591 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004591</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000118>P. berghei DNA vaccine encoding PbCSP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3949</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>3949</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium berghei DNA vaccine encoding PbCSP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004592 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004592</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>P. yoelii DNA vaccine pPyHsp60-VR1012</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3950</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3950</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii DNA vaccine pPyHsp60-VR1012</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004593 -->

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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004593</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii DNA vaccine encoding MSP1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004594 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004594</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000118>P. berghei DNA vaccine CSP-3p28</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium berghei DNA vaccine CSP-3p28</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004595 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004595</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3953</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3953</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>P. knowlesi DNA vaccine encoding PkCSP, PkSSP2, PkAMA1, and PkMSP1p42</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004596 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004596</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
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        <obo:VO_0001818>3954</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SHIV DNA vaccine encoding env and gag</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004597 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004597</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3955</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>3955</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SHIV(Ba-L) DNA vaccine encoding env and gag</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004598 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004598</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>GSK1437174A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004599 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004599">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001227"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10359"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004599</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3958</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>3958</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10359"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human cytomegalovirus DNA vaccine pcGB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004600 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004600">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004600</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3960</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>3960</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rBCG-SIVgag and rDIsSIVgag Prime-boost SHIV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004601 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004601">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000675"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004601</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. pneumoniae pspA-rBCG Vector Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3961</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001818>3961</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae pspA-rBCG vector vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004602 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004602">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004602</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii recombinant vaccine vector rBCGpMV361-TgCyP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3962</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>3962</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii recombinant vaccine vector rBCGpMV361-TgCyP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004603 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004603">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001522"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004603</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>AE-Poxine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3963</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>3963</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_70796"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AE-Poxine vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004604 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004604">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004604</metadata:prefixIRI>
        <obo:IAO_0000115>A dendritic cell vaccine consisting of dendritic cells (DCs) electroporated with mRNA encoding three adjuvants, CD40 ligand (CD40L), a constitutively active TLR4, and CD70 (all together termed TriMix); coelectroporated with full-length mRNA encoding MAGE-A3, MAGE-C2, Tyrosinase and gp100; and linked to DC-LAMP, with potential immunostimulating activity. Upon vaccination, the DCs may stimulate the immune system to mount an antigen-specific cytotoxic T-lymphocyte (CTL) response against the melanoma antigens. This may decrease cellular proliferation of melanoma cells expressing these antigens. Electroporation with the adjuvants CD40L and TLR4 allows for the generation of mature and active DCs; electroporation with CD70 provides a costimulatory signal to CD27+ naive T cells thereby supporting T-cell proliferation and inhibiting T-cell apoptosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5238</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/286</obo:IAO_0000233>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:OGG_0000000006>51438</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:OGG_0000000006>7099</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:OGG_0000000006>959</obo:OGG_0000000006>
        <obo:OGG_0000000006>970</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5238</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40LG</rdfs:comment>
        <rdfs:comment>Gene name: CD70</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:comment>Gene name: MAGEC2</rdfs:comment>
        <rdfs:comment>Gene name: TLR4</rdfs:comment>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>autologous TriMix-DC melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004605 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004605">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001074"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002792"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5867"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004605</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SL3261 expressing T. spiralis Ag30</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3969</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3969</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5867"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SL3261 expressing Trichinella spiralis Ag30 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004606 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004606">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_644"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004606</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3970</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3970</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_644"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Aeromonas hydrophila LSA34 vector vaccine WED/pUTDgap</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004607 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004607">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004607</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3972</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>3972</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Actinobacillus pleuropneumoniae HS93Tox-/pIG-T1K vectored vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004608 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004608">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004608</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3973</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>3973</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis BPZE vectored vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004609 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004609">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004609</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>pCR3.1-VS-HSP65-TP-GRP6-M2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3987</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3987</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>pCR3.1-VS-HSP65-TP-GRP6-M2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004610 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004610">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004610</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SRL172</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4001</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4001</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>SRL172 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004611 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004611">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004611</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>VMCL</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4019</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4019</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>VMCL vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004612 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004612">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004612</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Newcastle disease virus lysate</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4025</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4025</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle disease virus lysate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004613 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004613">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004613</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4044</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4044</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>smallpox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004614 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004614">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004614</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22896657</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4054</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4054</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mRNA-electroporated dendritic cells encoding gp100 and tyrosinase as melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004615 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004615">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004615</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>pcDNA3-MCC/ST</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4057</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4057</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>pcDNA3-MCC/ST vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004616 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004616">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004616</metadata:prefixIRI>
        <obo:IAO_0000115>The approach focuses on the use of five primary patient derived melanoma cells (MEL-2, MEL-V, 3MM, KFM, and GLM-2). These cells display differential in vitro migratory and invasive properties as well as have the ability to form solid tumors when implanted into BALB/c nude mice. The retention of the innate phenotype of these primary patient derived cells together with the expression of a multitude repertoire of melanoma associated antigens offers a novel opportunity to target melanoma so as to avoid immune evasion</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4064</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/557</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4064</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>Multivalent immunotherapeutic vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004617 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004617">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004617</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>short overlapping peptides and full-length recombinant protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4079</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4079</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>short overlapping peptides and full-length recombinant protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004618 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004618">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004618</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BCG-DHTM</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4082</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4082</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG-DHTM vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004619 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004619">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001524"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004619</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rSPV-PCV2-cap</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4083</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4083</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rSPV-PCV2-cap vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004620 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004620">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004620</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>vFP89-H5</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4084</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4084</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vFP89-H5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004621 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004621">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004621</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>vNDV-H5</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4085</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4085</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vNDV-H5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004622 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004622">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001497"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004622</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>fp-IBD1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4087</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>4087</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>fp-IBD1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004623 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004623">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004623</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rDEV-re6 (H5)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4088</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4088</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rDEV-re6 (H5) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004624 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004624">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004624</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4089</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4089</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FPV-LT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004625 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004625">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001497"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004625</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rFPV-IBDV-VP2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4091</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4091</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rFPV-IBDV-VP2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004626 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004626">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004626</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>LT-BCG- Ag85B /Rv3425</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4092</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4092</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>LT-BCG- Ag85B /Rv3425 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004627 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004627">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001231"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004627</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. T -PpSP15</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4095</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4095</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania T -PpSP15 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004628 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004628">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012159"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004628</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>A2-CPA-CPB(-CTE)-recombinant L. tarentolae</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4096</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>4096</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>A2-CPA-CPB(-CTE)-recombinant L. tarentolae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004629 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004629">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004629</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>L. T -HIV-1 Gag</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4097</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4097</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania tarentolae expressing HIV-1 Gag vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004630 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004630">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004630</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>AdC68- rabies virus glycoprotein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4099</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>4099</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AdC68- rabies virus glycoprotein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004631 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004631">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004631</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rAd-GP (Ebola virus)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4100</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>4100</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rAd-GP Ebola virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004632 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004632">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004632</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>HVT-ND</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4102</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4102</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HVT-ND vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004633 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004633">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004633</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rHVT-H5</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4103</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4103</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rHVT-H5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004634 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004634">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004634</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rHVT-H5 (clade 2.2 H5N1 HPAIV)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4104</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4104</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rHVT-H5 (clade 2.2 H5N1 HPAIV) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004635 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004635">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002788"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1307"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004635</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rSPV-MRP (Streptococcus suis)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4106</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4106</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1307"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rSPV-MRP Streptococcus suis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004636 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004636">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004636</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rSPV-HA1 (Swine influenza virus H1N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4107</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4107</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rSPV-HA1 (Swine influenza virus H1N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004637 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004637">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004637</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>HS93Tox-/pIG-T1K</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4108</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9823"/>
        <obo:VO_0001818>4108</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HS93Tox-/pIG-T1K vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004638 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004638">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004638</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-SIV/gp120</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4110</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4110</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-SIV/gp120 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004639 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004639">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004639</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-rabies</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4111</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>4111</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-rabies vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004640 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004640">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002506"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004640</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>E. coli-CPPs (Edwardsiella tarda)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4112</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4112</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli-CPPs Edwardsiella tarda vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004641 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004641">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004641</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CAdVax-ZEBOV/SEBOV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4113</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>4113</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CAdVax-ZEBOV/SEBOV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004642 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004642">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012166"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11588"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004642</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CAdVax-RVFV glycoprotein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4114</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4114</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11588"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CAdVax-RVFV glycoprotein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004643 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004643">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000725"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004643</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CAdVax-Den12/Den34</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4115</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
        <obo:VO_0001818>4115</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CAdVax-Den12/Den34 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004644 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004644">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004644</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CAdVax-Filoviruses (Ebola )</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4116</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>4116</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CAdVax-Filoviruses (Ebola ) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004645 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004645">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004645</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CAdVa-Filoviruses (EbMarburg viruses)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4117</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4117</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CAdVa-Filoviruses (EbMarburg viruses) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004646 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004646">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004646</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>cAdVaxM(fus)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4118</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4118</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>cAdVaxM(fus) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004647 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004647">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004647</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4119</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>4119</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>cAdVax-based bivalent ebola virus vaccine (Sudan and Zaire species)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004648 -->

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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004648</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RB51-SRS2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4120</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4120</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RB51-SRS2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004649 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004649</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RB51-MIC3/GRA6/MIC1/SRS2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4121</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4121</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_29176"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RB51-MIC3/GRA6/MIC1/SRS2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004650 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004650">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004650</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BPZE1- FHA (H1N1/PR8 influenza A virus)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4122</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4122</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BPZE1- FHA (H1N1/PR8 influenza A virus) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004651 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004651">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004651</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BV-RVG/RVG</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4124</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>4124</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BV-RVG/RVG vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004652 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004652">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001497"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004652</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BV-Dual-S1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4125</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4125</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BV-Dual-S1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004653 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004653">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004653</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>AcHERV-sH1N1-HA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4126</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4126</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AcHERV-sH1N1-HA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004654 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004654">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004654</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BV-H5/H7/H9</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4128</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4128</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BV-H5/H7/H9 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004655 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004655">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001211"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10497"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004655</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BacMam-sHAPQ</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4129</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4129</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10497"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BacMam-sHAPQ vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004656 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004656">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004656</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rBCGpMV361-TgCyP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4130</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4130</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rBCGpMV362-TgCyP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004657 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004657">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83334"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004657</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rBCG -Stx2B (Escherichia coli )</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4131</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4131</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83334"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rBCG -Stx2B E. coli vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004658 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004658">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004658</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rDEV-us78HA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4136</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4136</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rDEV-us78HA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004659 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004659</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>VSV-DeltaG-H5 (H5N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4137</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4137</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VSV-DeltaG-H5 (H5N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004660 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004660">
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004660</metadata:prefixIRI>
        <obo:IAO_0000115>An Ebola virus vaccine that uses a recombinant vesicular stomatitis virus (rVSV) vector expressing an Ebola filovirus glycoprotein</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>rVSV-EBOV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4140</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>4140</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rVSV-EBOV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004661 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004661">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004661</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rVSV- SEBOV-GP and -VP40</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4141</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>4141</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rVSV- SEBOV-GP and -VP40 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004662 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004662">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004662</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rVSVDeltaG-ANDV-GPC</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4142</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4142</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rVSVDeltaG-ANDV-GPC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004663 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004663">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012166"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11588"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004663</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMVA-GnGc (Rift Valley fever virus)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4143</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4143</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11588"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMVA-GnGc (Rift Valley fever virus) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004664 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004664">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000751"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004664</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4144</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4144</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMVA-SIV-CD40L Simian immunodeficiency virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004665 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004665">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001365"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052518"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004665</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMVA-CCHF</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4145</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4145</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052518"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMVA-CCHF vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004666 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004666">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002785"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0050012"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_37124"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004666</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>MVA-CHIKV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4146</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0050012"/>
        <obo:VO_0001818>4146</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_37124"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVA-CHIKV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004667 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004667">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004667</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>MVTT-HA-QH</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4149</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4149</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVTT-HA-QH vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004668 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004668">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001229"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004668</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. gordonii -M6-Sj-F1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4150</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4150</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Schistosoma gordonii -M6-Sj-F1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004669 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004669">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000640"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004669</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Streptococcus gordonii-TTFC</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4151</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>4151</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus gordonii-TTFC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004670 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004670">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004670</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>S. gordonii-PT</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4152</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>4152</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>S. gordonii-PT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004671 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004671">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001231"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004671</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SL3261-L. major</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4153</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4153</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5664"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SL3261-Leishmania major vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004672 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004672">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004672</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SL3261-L. donovani</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4154</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4154</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SL3261-L. donovani vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004673 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004673">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003495"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004673</metadata:prefixIRI>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <rdfs:label>quadrivalent influenza vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004674 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004674">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000393"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004674</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SL3261-P. aeruginosa serogroup O11 O antigen</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4156</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4156</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_287"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SL3261-Pseudomonas aeruginosa serogroup O11 O antigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004675 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004675">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004675</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SL3261- UreA and UreB</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4157</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4157</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SL3262- UreA and UreB vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004676 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004676">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004676</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SL3261 expressing streptococcal M protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4158</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4158</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1314"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SL3261 expressing streptococcal M protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004677 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004677">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004677</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Schmidt-Ruppin Rous sarcoma virus-H7 (H7N7)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4159</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4159</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Schmidt-Ruppin Rous sarcoma virus-H7 (H7N7) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004678 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004678">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004678</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RBD-rAAV-SARS-CoV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4160</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/18708674/</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4160</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RBD-rAAV-SARS-CoV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004679 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004679">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004679</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RBD-rAAV-SARS-CoV prime/RBD-specific T cell peptide boost</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4161</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/18289745/</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4161</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RBD-rAAV-SARS-CoV prime/RBD-specific T cell peptide boost vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004680 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004680">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004680</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rNDV-ILTV-gD</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4162</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4162</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rNDV-ILTV-gD vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004681 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004681">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004681</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rNDV-H5</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4163</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4163</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rNDV-H5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004682 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004682">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004682</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rNDV-H5 ( HPAI H5N1 challenge in mule ducks)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4164</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4164</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rNDV-H5 ( HPAI H5N1 challenge in mule ducks) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004683 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004683">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004683</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rNDV-H6</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4165</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4165</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rNDV-H6 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004684 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004684">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004684</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rAPMV3-F (newcastle disease)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4167</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4167</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rAPMV3-F newcastle disease vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004685 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004685">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001366"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39944"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004685</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BoHV-4-A-gD(cp)gD(106)DeltaTK</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4168</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4168</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_39944"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BoHV-4-A-gD(cp)gD(106)DeltaTK vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004686 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004686">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001466"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001515"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004686</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BoHV-4-A-IgK-VP2gD</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4169</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9913"/>
        <obo:VO_0001818>4169</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BoHV-4-A-IgK-VP2gD vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004687 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004687">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000658"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004687</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>HSVT[VP7/6/2]</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4172</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
        <obo:VO_0001818>4172</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HSVT[VP7/6/2] vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004688 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004688">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012181"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004688</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M. S- H. pylori -opm26</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4173</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4173</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>M.S-Helicobacter pylori-opm26 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004689 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004689">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004689</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M.S-Delta-esx-3-IKEPLUS (M. tuberculosis)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4174</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>4174</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>M.S-Delta-esx-3-IKEPLUS Mycobacterium tuberculosis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004690 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004690">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004690</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>YF17D- HIV-1 p24</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4175</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4175</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>YF17D- HIV-1 p24 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004691 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004691">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004691</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RCN-HA (H5N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4176</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4176</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RCN-HA (H5N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004692 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004692">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004692</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RCN-F1-V (Yersinia pestis F1 and V)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4177</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4177</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RCN-F1-V Yersinia pestis F1 and V vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004693 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004693">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004693</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RCN-rabies-G</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4178</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>4178</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RCN-rabies-G vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004694 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004694">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000648"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004694</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RCN-IRES-tPA-YpF1( Yersinia pestis)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4179</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4179</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_632"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RCN-IRES-tPA-YpF1 Yersinia pestis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004695 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004695">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004695</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>PAV3-HA (H5N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4180</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4180</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PAV3-HA (H5N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004696 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004696">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004696</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>PAV3-HA (A/Hanoi/30408/2005 H5N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4181</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4181</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PAV3-HA (A/Hanoi/30408/2005 H5N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004697 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004697">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000329"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2099"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004697</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rAd-P97c</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4182</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4182</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2099"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rAd-P97c vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004698 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004698">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004698</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>PrV-HA (swine-origin H1N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4183</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4183</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PrV-HA (swine-origin H1N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004699 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004699">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001524"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004699</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>PrV-PCV2-ORF2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4184</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4184</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PrV-PCV2-ORF2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004700 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004700">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004700</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rAdV-SFV-E2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4185</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4185</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rAdV-SFV-E2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004701 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004701">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004701</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4186</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4186</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhi strain Ty21a-LPS-Shigella</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004702 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004702">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004702</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Typhi strain Ty21a-PA (Bacillus anthracis)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4187</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>4187</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhi strain Ty21a-PA Bacillus anthracis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004703 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004703">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004703</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4188</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4188</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_620"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ty21a-O-Ps (Shigella dysenteriae )</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004704 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004704">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000751"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004704</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SabRV-SIV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4189</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4189</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SabRV-SIV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004705 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004705">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004705</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Poliovirus vector expressing model antigen H2-Kb-restricted CTL epitope</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4190</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4190</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>poliovirus vector expressing model antigen H2-Kb-restricted CTL epitope vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004706 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004706">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001476"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001515"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004706</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SG33-VP2/5</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4191</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9940"/>
        <obo:VO_0001818>4191</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SG33-VP2/5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004707 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004707">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001509"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11978"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004707</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Myxoma-FCV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4192</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4192</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11978"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Myxoma-FCV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004708 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004708">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004708</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4193</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/496</obo:IAO_0000233>
        <obo:OGG_0000000006>727897</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4193</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC5B</rdfs:comment>
        <rdfs:label>Maraba virus MG1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004709 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004709">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000656"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004709</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rvOka-HN (mumps virus)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4194</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10264"/>
        <obo:VO_0001818>4194</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rvOka-HN mumps virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004710 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004710">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012168"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004710</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rOka-gD2- HSV-2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4195</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4195</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rOka-gD2- HSV-2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004711 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004711">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004711</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMV- SARS-CoV -S/Ssol</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4196</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4196</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMV- SARS-CoV -S/Ssol vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004712 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004712">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000752"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004712</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMV- WNV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4197</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4197</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMV- WNV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004713 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004713">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4947"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004713</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMeV- SCD</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4198</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4947"/>
        <obo:VO_0001818>4198</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>rMeV- SCD vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004714 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004714">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004714</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMV-Ed-G</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4199</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4199</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMV-Ed-G vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004715 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004715">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000013"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004715</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rLAG- PA-DCpep</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4200</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_7427"/>
        <obo:VO_0001818>4200</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rLAG- PA-Dcpep vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004716 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004716">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004716</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMCMV-TRP2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4201</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4201</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>rMCMV-TRP2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004717 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004717">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004717</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rCMV- EBOV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4202</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>4202</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rCMV- EBOV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004718 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004718">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000640"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004718</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rCMV-TT</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4203</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001818>4203</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rCMV-TT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004719 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004719">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004719</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CVB4/p24(73(3))</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4204</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4204</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CVB4/p24(73(3)) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004720 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004720">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001207"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_813"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004720</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rVCG- Chlamydia-cholera</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4205</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4205</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_813"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rVCG- Chlamydia-cholera vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004721 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004721">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000041"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83334"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004721</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>CVD 103-HgR- REPEC</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4206</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4206</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83334"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CVD 103-HgR- REPEC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004722 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004722">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001207"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_813"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004722</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rVCG- MOMP/HSV-2-gD</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4207</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4207</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_813"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rVCG- MOMP/HSV-2-gD vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004723 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004723">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012168"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004723</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>pRP-RSV-HSV-1-gB</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4208</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4208</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pRP-RSV-HSV-2-gB vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004724 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004724">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004724</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>RSV-H7</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4209</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4209</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RSV-H7 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004725 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004725">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001480"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40050"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004725</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-AHSV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4210</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4210</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40050"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-AHSV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004726 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004726">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001515"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004726</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-BTV-VP2/VP5</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4211</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4211</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-BTV-VP2/VP5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004727 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004727">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004727</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-HIV-2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4212</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4212</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-HIV-2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004728 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004728">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004728</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-RV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4213</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>4213</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-RV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004729 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004729">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004729</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>FP-AI-H5(H5N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4214</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4214</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FP-AI-H5(H5N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004730 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004730">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004730</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-AI-H5(H5N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4215</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4215</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-AI-H5(H5N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004731 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004731">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000752"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004731</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-WNV-prM/E</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4216</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4216</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-WNV-prM/E vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004732 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004732">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001515"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004732</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-BTV-CP(VP2/VP5)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4218</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4218</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-BTV-CP(VP2/VP5) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004733 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004733">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004733</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-NiV-G</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4219</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4219</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-NiV-G vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004734 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004734">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012169"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004734</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-NiV-F</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4220</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4220</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-NiV-F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004735 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004735">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004735</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-EIV (equine influenza virus H3N8)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4221</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4221</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-EIV (equine influenza virus H3N8) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004736 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004736">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000752"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004736</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-WNV-PrM/E (dogs and cats)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4222</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4222</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11082"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-WNV-PrM/E (dogs and cats) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004737 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004737">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004737</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-HIV-2- env/gag/pol</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4223</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4223</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-HIV-2- env/gag/pol vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004738 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004738">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001382"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11976"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004738</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-RHDV (vCP309)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4224</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4224</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11976"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-RHDV (vCP309) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004739 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004739">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004739</metadata:prefixIRI>
        <obo:IAO_0000115>Several canarypox virus recombinants expressing human or murine p53 in wild-type or mutant form were constructed</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:12006514</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4225</obo:IAO_0000119>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4225</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TP53 (P53)</rdfs:comment>
        <rdfs:label>ALVAC-P53 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004740 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004740">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000843"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004740</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-FL- env/gag</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4226</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4226</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11768"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-FL- env/gag vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004741 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004741">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000654"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004741</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-MV-HA/F</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4227</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
        <obo:VO_0001818>4227</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-MV-HA/F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004742 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004742">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001497"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004742</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>FP-IBDV-VP2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4228</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4228</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FP-IBDV-VP2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004743 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004743">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004743</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rFPV-AI-H5A-IL6</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4229</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4229</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rFPV-AI-H5A-IL6 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004744 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004744">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004744</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rFPV-ILTV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4230</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4230</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rFPV-ILTV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004745 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004745">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004745</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>vFP89-HA (H5N1 HPAI virus)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4231</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4231</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vFP89-HA (H5N1 HPAI virus) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004746 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004746">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004746</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rFPV-H5AI-L2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4232</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4232</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rFPV-H5AI-L2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004747 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004747">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004747</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-AI-H5</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4233</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4233</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-AI-H5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004748 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004748">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004748</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rPFV-CSFV-E0</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4234</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4234</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rPFV-CSFV-E0 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004749 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004749">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001497"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004749</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMDV-IBDV-VP2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4237</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4237</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMDV-IBDV-VP2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004750 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004750">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001497"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004750</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rFPV-IBDV-VP 2.4.3</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4239</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4239</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10995"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rFPV-IBDV-VP 2.4.3 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004751 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004751">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004751</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rFPV-NDV-H/F</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4240</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4240</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rFPV-NDV-H/F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004752 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004752">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001455"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11241"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004752</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rFP-RPV-H/F</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4241</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4241</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11241"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rFP-RPV-H/F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004753 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004753">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001502"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004753</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Ac-CMV-S1 (infectious bronchitis virus)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4242</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4242</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11120"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ac-CMV-S1 infectious bronchitis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004754 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004754">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001524"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004754</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BV-GD-ORF2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4243</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4243</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BV-GD-ORF2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004755 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004755">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004755</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rSPV/H3-2A-H1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4244</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4244</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rSPV/H3-2A-H1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004756 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004756">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004756</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4245</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4245</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HVT-ILT(FC-126 strain) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004757 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004757">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004757</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rBCG-Ag85A/Ag85B</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4246</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4246</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rBCG-Ag85A/Ag85B vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004758 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004758">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001480"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40050"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004758</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMVA- AHS-VP2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4248</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4248</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40050"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMVA- AHS-VP2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004759 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004759">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004759</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMVTT-HA-QH (H5N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4249</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4249</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMVTT-HA-QH (H5N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004760 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004760">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004760</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMVTT-SIV-gpe</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4250</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4250</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMVTT-SIV-gpe vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004761 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004761">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007656"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004761</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rMVTT- HPV16-E6/E7</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4251</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001818>4251</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>rMVTT- HPV16-E6/E7 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004762 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004762">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004762</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rLSDV-Rabies-gP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4253</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>4253</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rLSDV-Rabies-gP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004763 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004763">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001455"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11241"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004763</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rLSDV-RPV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4254</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4254</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11241"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rLSDV-RPV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004764 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004764">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004764</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4255</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/527</obo:IAO_0000233>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4255</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA1</rdfs:comment>
        <rdfs:label>MG1-hDCT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004765 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004765">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004765</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rORFV-D1701-V-HAh5n (H5N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4256</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4256</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rORFV-D1701-V-HAh5n (H5N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004766 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004766">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004766</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rORFV-RabG</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4257</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001818>4257</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rORFV-RabG vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004767 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004767">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001382"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11976"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004767</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rORFV-RHDV-VP60</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4258</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4258</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11976"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rORFV-RHDV-VP60 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004768 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004768">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004768</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rORFV-CSFV-E2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4259</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4259</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rORFV-CSFV-E2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004769 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004769">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001483"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12455"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004769</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rORFV-p40(Borna disease virus)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4260</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4260</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12455"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rORFV-p40(Borna disease virus) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004770 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004770">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004770</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rORFV-PRV-gC/gD</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4261</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4261</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rORFV-PRV-gC/gD vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004771 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004771">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001486"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004771</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC-EHV-1- vP1014</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4262</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4262</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10326"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC-EHV-1- vP1014 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004772 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004772">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004772</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC- CDV-H/F</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4263</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4263</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC- CDV-H/F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004773 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004773">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004773</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC- CDV-H/F</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4264</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4264</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC- CDV-H/F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004774 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004774">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004774</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC-HIV-1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4265</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4265</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC-HIV-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004775 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004775">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004775</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC-HIV-2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4266</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4266</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC-HIV-2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004776 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004776">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000665"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004776</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC-JEV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4267</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001818>4267</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC-JEV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004777 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004777">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000665"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004777</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ALVAC-JEV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4268</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001818>4268</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-JEV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004778 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004778">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000750"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004778</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC-PRV- gII/ gp50</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4270</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4270</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10345"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC-PRV- gII/ gp50 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004779 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004779">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004779</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC-SIV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4271</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4271</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC-SIV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004780 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004780">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000665"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004780</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC-JEV- prM/E/ NS1</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4274</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001818>4274</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC-JEV- prM/E/ NS1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004781 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004781">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004781</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>VC-TetC/Tcf</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4275</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>4275</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VC-TetC/Tcf vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004782 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004782">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001229"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004782</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rAdV-SjTPI.opt</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4280</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4280</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6182"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rAdV-SjTPI.opt vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004783 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004783">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004783</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rPIV5-H3 (influenza virus)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4282</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4282</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11309"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rPIV5-H3 (influenza virus) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004784 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004784">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004784</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rVEE-HA(H1N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4288</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4288</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rVEE-HA(H1N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004785 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004785">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004785</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rS.C-APP-ApxI/ApxII</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4289</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4289</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rS.C-APP-ApxI/ApxII vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004786 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004786">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004786</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rS.C-APP-ApxIIA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4290</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4290</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rS.C-APP-ApxIIA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004787 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004787">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004787</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>dVV-HA5(H5N1)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4293</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>4293</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>dVV-HA5(H5N1) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004788 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004788">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001515"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004788</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rCPV-BTV-Cpox</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4295</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4295</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_40051"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rCPV-BTV-Cpox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004789 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004789">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000751"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004789</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rBCG-SIVgag</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4299</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4299</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11723"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rBCG-SIVgag vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004790 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004790">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004790</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rBCG-S1PT</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4300</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>4300</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rBCG-S2PT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004791 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004791">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000761"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004791</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rBCGMSP1-15</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4301</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>4301</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rBCGMSP1-15 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004792 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004792">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004792</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4302</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001818>4302</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMVA-SIV-CD40L human immunodeficiency virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004793 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004793">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001488"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004793</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>HVT-LT</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4304</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4304</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10386"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HVT-LT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004794 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004794">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004794</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC-Pf7</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4269</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4306</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>4269</obo:VO_0001818>
        <obo:VO_0001818>4306</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC-Pf7 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004795 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004795">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002789"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1719"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004795</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>Toxminus-PLD toxoid</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4308</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001818>4308</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1719"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxminus-PLD toxoid vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004796 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004796">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004796</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>MVA-PvTRAP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4309</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>4309</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVA-PvTRAP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004797 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004797">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004797</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>ChAd63 -PvTRAP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4310</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>4310</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ChAd63 -PvTRAP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004798 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004798">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002514"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004798</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NILV-Py CSP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4094</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4311</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>4094</obo:VO_0001818>
        <obo:VO_0001818>4311</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NILV-Py CSP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004799 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004799">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004799</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>SAd-ME.TRAP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4277</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4312</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>4277</obo:VO_0001818>
        <obo:VO_0001818>4312</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SAd-ME.TRAP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004800 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004800">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004800</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>NYVAC-CSP (malaria)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4272</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4313</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>4272</obo:VO_0001818>
        <obo:VO_0001818>4313</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NYVAC-CSP malaria vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004801 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004801">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004801</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BDES-PfCSP (baculovirus dual expression system)</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4314</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>4314</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BDES-PfCSP vaccine (baculovirus dual expression system)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004802 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004802">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002512"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004802</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>HDAd-sFsyn</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4315</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4315</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11250"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>HDAd-sFsyn vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004803 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004803">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004803</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>LM1-2-E7</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4316</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001818>4316</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>LM1-2-E7 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004804 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004804">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0002506"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004804</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BL21(DE3)/pUTa-E + pET28a-FT</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4317</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>4317</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_636"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BL21(DE3)/pUTa-E + pET28a-FT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004805 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004805">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004805</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>rVEE-Ebola-NP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4318</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>4318</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rVEE-Ebola-NP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004806 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004806">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001519"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004806</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>M. bovis DNA vaccine pCI-Ag85B</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4319</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>4319</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium bovis DNA vaccine pCI-Ag85B</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004807 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004807">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001519"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010443"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004807</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>BCG</obo:IAO_0000118>
        <obo:IAO_0000118>Bacillus Calmette-Guérin Danish</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4320</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4320</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus Calmette-Guérin Danish vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004808 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004808">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000433"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010452"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004808</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Ronak Sutariya</obo:IAO_0000117>
        <obo:IAO_0000118>APSV Wetvax</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4321</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4321</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10255"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>APSV Wetvax vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004809 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0004810 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <obo:IAO_0000118>2010-2011 trivalent seasonal inactivated influenza vaccine (A/California/7/09 (H1N1), A/Perth/16/2009 (H3N2), and B/Brisbane/60/2008)</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0004811 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004811</metadata:prefixIRI>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <rdfs:label>Recombinant Aeromonas hydrophila vaccine (Aera)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004812 -->

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        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
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        <rdfs:label>C-KCE (vBAC-C-KCE) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004813 -->

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        <rdfs:label>v2RVFH vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004814 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004815 -->

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        <oboInOwl:hasDbXref>TUI: T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004816 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004816</metadata:prefixIRI>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/805574</obo:IAO_0000119>
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        <obo:VO_0003198>805574</obo:VO_0003198>
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        <obo:VO_0003560>rotavirus vaccine, live attenuated, G1P[8] human 89-12 strain 1000000 UNT/ML</obo:VO_0003560>
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        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 UNT/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004817 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004817">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010738"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004817</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>805577</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
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        <obo:VO_0010151>19131939</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2364572</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2861607</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 UNT/ML [Rotarix]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004818 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004818">
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        </rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004818</metadata:prefixIRI>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>CUI: C2343398</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 8728820, 8728821, 2861609</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotarix, Rotavirus, live attenuated (RV1) G1P[8] Oral Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004819 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004819</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>CUI: C3236400</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3845652</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rotarix Oral Liquid Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004820 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>798292</obo:VO_0003198>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G4 Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004821 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>798293</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <obo:VO_0003560>human-bovine reassortant rotavirus strain G4 vaccine 1000000 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>529215</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344316</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851376</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 1000000 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004822 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004822">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010449"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004822</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/798294</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>798294</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <obo:VO_0003560>human-bovine reassortant rotavirus strain P1A[8] vaccine</obo:VO_0003560>
        <obo:VO_0005279>human rotavirus A type G6P1A(8) strain WI79 live antigen</obo:VO_0005279>
        <obo:VO_0010151>529216</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344317</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851377</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T116, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004823 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004823">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010449"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004823</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/798288</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>798288</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <obo:VO_0003560>human-bovine reassortant rotavirus strain G2 vaccine</obo:VO_0003560>
        <obo:VO_0005279>human rotavirus A type G2P7(5) strain SC2 live antigen</obo:VO_0005279>
        <obo:VO_0010151>529180</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344311</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851371</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T116, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G2 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004824 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004824">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010449"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004824</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/798290</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005194"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>798290</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <obo:VO_0003560>human-bovine reassortant rotavirus strain G3 vaccine</obo:VO_0003560>
        <obo:VO_0005279>human rotavirus A type G3P7(5) strain WI78 live antigen</obo:VO_0005279>
        <obo:VO_0010151>529212</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344313</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851373</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T116, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G3 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004825 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004825">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010449"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004825</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>798286</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <obo:VO_0003560>human-bovine reassortant rotavirus strain G1 vaccine</obo:VO_0003560>
        <obo:VO_0005279>human rotavirus A type G1P7(5) strain WI79 live antigen</obo:VO_0005279>
        <obo:VO_0010151>529176</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344309</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851369</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T116, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G1 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004826 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004826">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004824"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004826</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>798291</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <obo:VO_0003560>human-bovine reassortant rotavirus strain G3 vaccine 1100000 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>529213</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344314</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851374</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 1100000 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004827 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004827">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004825"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004827</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>798287</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <obo:VO_0003560>human-bovine reassortant rotavirus strain G1 vaccine 1100000 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>529177</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C2344310</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851370</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 1100000 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004828 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004828">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004822"/>
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        <rdfs:subClassOf>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>798295</obo:VO_0003198>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 1150000 UNT/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004829 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004829</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>798289</obo:VO_0003198>
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        <oboInOwl:hasDbXref>CUI: C2344312</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 2851372</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 1400000 UNT/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004830 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>RXAUI: 3845650</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RotaTeq Oral Liquid Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004831 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004831</metadata:prefixIRI>
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    <!-- http://purl.obolibrary.org/obo/VO_0004832 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0004833 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004837 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004838 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Trumenba Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004848 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004849 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>Trumenba vaccine Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004850 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004851 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004852 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004853 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>1601407</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
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        <obo:VO_0005279>Bexsero Meningococcal Group B Vaccine 0.5 ML Prefilled Syringe</obo:VO_0005279>
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        <rdfs:label>BEXSERO vaccine 0.5 ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004854 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>RXAUI: 2944708</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>smallpox vaccine live vaccinia virus</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004855 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <rdfs:label>smallpox vaccine live vaccinia virus 500000000 UNT/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004856 -->

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        <rdfs:label>ACAM2000 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004857 -->

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        <rdfs:label>ACAM2000 smallpox (vaccinia) vaccine, live Injectable Solution</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004858 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004859 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000919"/>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/29503</obo:IAO_0000119>
        <obo:VO_0003198>29503</obo:VO_0003198>
        <obo:VO_0003560>meningococcal group C polysaccharide</obo:VO_0003560>
        <obo:VO_0010151>509081</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>CUI: C0065944</rdfs:comment>
        <rdfs:comment>RXAUI: 436480, 5945194, 6410398</rdfs:comment>
        <rdfs:comment>TUI: T109, T129, T121</rdfs:comment>
        <rdfs:label>meningococcal group C polysaccharide</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004860 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004860">
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004860</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>314725</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <obo:VO_0003560>meningococcal polysaccharide vaccine group Y</obo:VO_0003560>
        <obo:VO_0010151>514015</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C0982276</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 1473942</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T109, T129, T121</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004861 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004861">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010290"/>
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            <owl:Restriction>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004861</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>1437844</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <obo:VO_0003560>meningococcal group C polysaccharide 0.01 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>43560725</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group C polysaccharide 0.01 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004862 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004862">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010290"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010444"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004862</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003198>350967</obo:VO_0003198>
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        <obo:VO_0003560>meningococcal group C polysaccharide 0.1 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>19097997</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group C polysaccharide 0.1 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004863 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004863">
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004863</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>1437845</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <obo:VO_0003560>meningococcal polysaccharide vaccine group Y 0.01 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>43560588</obo:VO_0010151>
        <oboInOwl:hasDbXref>CUI: C3666862</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 5495921</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.01 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004864 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004864</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003198>350966</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
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        <oboInOwl:hasDbXref>CUI: C1167602</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 1545435</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.1 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004865 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004865</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:hasDbXref>CUI: C3666883</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 5496016</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MenHibrix Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004866 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004866</metadata:prefixIRI>
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        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/VO_0004868"/>
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        <obo:VO_0003560>Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.005 MG/ML / meningococcal group C polysaccharide 0.01 MG/ML / meningococcal polysaccharide vaccine group Y 0.01 MG/ML [MenHibrix]</obo:VO_0003560>
        <obo:VO_0010151>43560549</obo:VO_0010151>
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    <!-- http://purl.obolibrary.org/obo/VO_0004867 -->

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        <obo:VO_0005279>MenHibrix (meningococcal groups C and Y and Haemophilus b tetanus toxoid conjugate vaccine) 0.5 ML Injection</obo:VO_0005279>
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        <rdfs:label>MENHIBRIX vaccine 0.5 ML Injection</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004868 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004869 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004870 -->

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        <rdfs:label>Menomune A/C/Y/W-135 Injectable Product</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004871 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004872 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004873 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1579"/>
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        <rdfs:label>Adenovirus Type 7 Vaccine Live Pill</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004879 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>CUI: C3153712</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 6337292</oboInOwl:hasDbXref>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Adenovirus Type 7 Vaccine Live Delayed Release Oral Tablet</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004880 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:hasDbXref>RXAUI: 6337842, 6364883</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Adenovirus Type 7 Vaccine Live 32000 UNT Delayed Release Oral Tablet</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004881 -->

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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Adenovirus Type 7 Vaccine Live 32000 UNT</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004882 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004883 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004884 -->

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        <obo:VO_0005279>Menomune A/C/Y/W-135 (meningococcal group A polysaccharide 50 MCG / meningococcal group C polysaccharide 50 MCG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 50 MCG / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 50 MCG) per 0.5 ML Injection</obo:VO_0005279>
        <obo:VO_0010151>46275263</obo:VO_0010151>
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        <oboInOwl:hasDbXref>RXAUI: 7253594, 7252562, 7252553</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
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    <!-- http://purl.obolibrary.org/obo/VO_0004885 -->

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        <oboInOwl:hasDbXref>CUI: C0708576</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>RXAUI: 3051640, 7253593, 5944304, 1155623</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TUI: T200</oboInOwl:hasDbXref>
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        <rdfs:label>Menomune A/C/Y/W-135 Vaccine Injectable Solution</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004886 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004887 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004888 -->

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        <rdfs:label>meningococcal group A polysaccharide</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0004889 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004890 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0004891 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0004893 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197911"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000694"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0021054"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004893</metadata:prefixIRI>
        <obo:IAO_0000115>Fluenz is a seasonal trivalent live attenuated influenza vaccine (LAIV) administered intranasally. The vaccine contained A/California/07/2009 (H1N1) pdm09-like strain, A/Victoria/361/2011 (H3N2)-like strain, and B/Massachusetts/2/2012-like strain.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/26148331</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197911"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluenz vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004894 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004894">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004894</metadata:prefixIRI>
        <obo:IAO_0000115>quadrivalent seasonal inactivated influenza vaccine 2014 consisting of Influenza A virus (A/California/7/2009(H1N1)), Influenza A virus (A/Texas/50/2012(H3N2)), Influenza B virus (B/Brisbane/60/2008), Influenza B virus (B/Massachusetts/02/2012)</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>Avey et al 2019, paper submitted</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>quadrivalent seasonal inactivated influenza vaccine 2014</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004895 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004895">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001194"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004895</metadata:prefixIRI>
        <obo:IAO_0000112>F&apos; (intended to refer to a female biological sex), &apos;Female&apos;, &apos;Woman&apos;, &apos;0&apos; (intended to refer to a female biological sex)</obo:IAO_0000112>
        <obo:IAO_0000115>A biological sex datum that represents the biological sex of an animal (including human) as being female.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Paul Fabry</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>female biological sex datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004896 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004896">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001194"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004896</metadata:prefixIRI>
        <obo:IAO_0000112>I&apos; (intended to refer to an intersex biological sex), &apos;Intersex&apos;, &apos;Hermaphrodite&apos;, &apos;Pseudo-hermaphrodite&apos;, &apos;2&apos; (intended to refer to an intersex biological sex)</obo:IAO_0000112>
        <obo:IAO_0000115>A biological sex datum that represents the biological sex of an animal (including human) as being intersex.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Paul Fabry</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>intersex biological sex datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004897 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004897">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11118"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11118"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004897</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine against coronavirus infection</obo:IAO_0000115>
        <obo:IAO_0000117>Hong Yu</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11118"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>coronavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004898 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004898">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004898</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.fludb.org/brc/fluStrainDetails.spg?strainName=A/Perth/16/2009(H3N2)&amp;decorator=influenza</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Recommended by WHO for Vaccines: 
2011-2012 Northern Hemisphere
2010 Southern Hemisphere
2011 Southern Hemisphere
2012 Southern Hemisphere
2010-2011 Northern Hemisphere</rdfs:comment>
        <rdfs:label>Influenza A virus A/Perth/16/2009 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004899 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004899">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001236"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000200"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0004902"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004899</metadata:prefixIRI>
        <obo:IAO_0000115>2012-2013 trivalent seasonal inactivated influenza vaccine 2012-2013  Influenza A virus (A/California/7/2009 (H1N1)), Influenza A virus (A/Victoria/361/2011 (H3N2)), and Influenza B virus (B/Wisconsin/1/2010)</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=30843873</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000200"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0004901"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0004902"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>2012-2013 seasonal trivalent inactivated influenza vaccine (A/California/7/2009 (H1N1), A/Victoria/361/2011 (H3N2), and B/Wisconsin/1/2010)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004900 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004900">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004897"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004900</metadata:prefixIRI>
        <obo:IAO_0000118>MERS-CoV vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004901 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004901">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015086"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004901</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.drugbank.ca/drugs/DB14396</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Wisconsin/1/2010 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004902 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004902">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004902</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.fludb.org/brc/fluStrainDetails.spg?strainName=A/Victoria/361/2011(H3N2)&amp;decorator=influenza</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Recommended by WHO for Vaccines:
2013 Southern Hemisphere
2014 Southern Hemisphere
2012-2013 Northern Hemisphere
2013-2014 Northern Hemisphere</rdfs:comment>
        <rdfs:label>influenza A virus A/Victoria/361/2011 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004903 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004903">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000065"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004903</metadata:prefixIRI>
        <obo:IAO_0000115>Inactivated monovalent influenza A/H5N1 (3.75 mcg hemagglutinin [HA] A/Indonesia/05/2005) split-virus (SV) vaccine (Sanofi)</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/28099485</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/30566602</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0004904"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated monovalent influenza A/H5N1 (3.75 mcg hemagglutinin [HA] A/Indonesia/05/2005) split-virus (SV) vaccine (Sanofi)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004904 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004904">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004904</metadata:prefixIRI>
        <obo:IAO_0000119>https://www.fludb.org/brc/fluStrainDetails.spg?strainName=A/Indonesia/5/2005(H5N1)&amp;tabName=17535101%20No2&amp;decorator=influenza&amp;context=1544988803656</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Influenza A virus (A/Indonesia/05/2005) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004905 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004905">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0004907"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004905</metadata:prefixIRI>
        <obo:IAO_0000118>MERS-CoV S protein with alum and CpG adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884803/</obo:IAO_0000119>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0004907"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS-CoV S protein with alum and CpG adjuvant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004906 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004906">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004906</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>MERS-CoV protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004907 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004907">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004906"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004907</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>MERS-CoV S protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004908 -->

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        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004897"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004908</metadata:prefixIRI>
        <obo:IAO_0000115>A coronavirus vaccine against the infection of SARS-CoV-2 (cause of COVID-19)</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>SARS-CoV-2 vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/COVID-19_vaccine</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/covid-19-vaccines</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>COVID-19 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004910 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004910">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0005569"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004910</metadata:prefixIRI>
        <obo:IAO_0000115>A Plasmodium falciparum vaccine that is composed of aseptic, purified, live (metabolically active), radiation-attenuated, cryopreserved Plasmodium falciparum sporozite.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>Plasmodium falciparum sporozite Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/26469720</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/28216244</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PfSPZ vaccine by Sanaria Inc</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004911 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004911">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0005569"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004911</metadata:prefixIRI>
        <obo:IAO_0000115>The fully infectious PfSPZ are attenuated in vivo by concomitant administration of an anti-malarial drug (chloroquine). Chloroquine kills disease-associated blood stages but does not affect pre-erythrocytic (sporozoite or liver) stages, which are exposed to the host&apos;s immune system. Sporozoites-induced protection is mediated by immunity against pre-erythrocytic stages.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>PfSPZ Chemoprophylaxis Vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>PfSPZ-Cvac</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775905/</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/26469720</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/28199305</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PfSPZ-Cvac vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004912 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004912">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0005569"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004912</metadata:prefixIRI>
        <obo:IAO_0000115>Sanaria(R) PfSPZ-GA1 consists of purified, aseptic, cryopreserved Pf sporozoites (NF54 strain) genetically attenuated by removal of the b9 and slarp genes to halt development in the early liver stages.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>PfSPZ-GA1</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/26469720</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>The parasite line was generated by the Leiden University Medical Center (LUMC) and RUMC in collaboration with Sanaria. Plasmodium falciparum with deletion b9 and slarp parasites invade hepatocytes but are incapable of sustaining liver stage development, similar to radiation-attenuated PfSPZ. The potential advantages of PfSPZ-GA1 are that (1) the PfSPZ are homogenous and have a precisely characterized genetic basis for attenuation; (2) manufacturing PfSPZ-GA1 cannot result in accidental exposure of staff to infectious parasites, thereby simplifying the approach to safety of operators and lowering costs. PfSPZ-GA1 also has the potential to induce more efficient protection than the radiation-attenuated PfSPZ Vaccine due to a different pattern of developmental arrest and antigen expression. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077156/</rdfs:comment>
        <rdfs:label>PfSPZ-GA1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004913 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004913">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004913</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine role that inheres in a vaccine using virus-like particles (VLPs), multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccines.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>virus like particle vaccine role</obo:IAO_0000118>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/20923267/</obo:IAO_0000119>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>virus-like particle vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004914">
        <owl:equivalentClass>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
                    </owl:Restriction>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004914</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that uses virus-like particles (VLPs), multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccines.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>virus like particle vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/20923267/</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>virus-like particle vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004915 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004915">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000100"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004915</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine-induced T-helper 1 type immune response that is indicated by the presence of Interferon-gamma production</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine specific interferon-γ immune response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004916 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004916">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000100"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004916</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine-induced T-helper 1 type immune response that is indicated by the presence of interleukin-2 production</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine specific IL-2 immune response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004917 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004917">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000101"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004917</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine-induced T-helper 2 type immune response that is indicated by the presence of interleukin-4 production</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine specific interleukin-4 response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004918 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004918">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000101"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004918</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine-induced T-helper 2 type immune response that is indicated by the presence of interleukin-10 production</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine specific interleukin-10 response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004919 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004919">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000100"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004919</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine-induced T-helper 1 type immune response that is indicated by the presence of IgG2a production</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101669/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine specific Th1 immune response indicated by IgG2a  production</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004920 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004920">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000101"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004920</metadata:prefixIRI>
        <obo:IAO_0000115>vaccine-induced T-helper 2 type immune response that is indicated by the presence of IgG1 production</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101669/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine specific Th2 immune response indicated by IgG1  production</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004921 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004921">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000011"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004921</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000052 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:label>human age</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004922 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004922">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004921"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004922</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:label>child age</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004923 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004923">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004921"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004923</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:label>adolescence age</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004924 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004924">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004921"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004924</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:label>adult age</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004925 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004925">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004921"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004925</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>quality</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:label>senior age</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004926 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004926">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004926</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>age range at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004927 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004927">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004926"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004927</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:label>human age range at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004928 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004928">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004927"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004928</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>human age 0 to 12 years at vaccination</obo:IAO_0000118>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human child age range at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004929 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004929">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004927"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004929</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>human age 19 to 59 years at vaccination</obo:IAO_0000118>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human adult age range at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004930 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004930">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004927"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004930</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>human age 60 and above years at vaccination</obo:IAO_0000118>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human senior age range at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004931 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004931">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004927"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004931</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>human age 13 to 18 years at vaccination</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:label>human adolescence age range at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004933 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004933">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004933</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 1 to 2 months at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004934 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004934">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004934</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 4 months at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004935 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004935">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004935</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 11 to 12 years at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004936 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004936">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004936</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 4 to 6 years at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004937 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004937">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004937</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 7 to 11 months at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004938 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004938">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004938</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 12 to 23 months at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004939 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004939">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004939</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 2 to 3 years at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004940 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004940">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004940</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 6 months at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004941 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004941">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004941</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 7 to 10 years at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004942 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004942">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004929"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004942</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 19 to 26 years at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004943 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004943">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004929"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004943</metadata:prefixIRI>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age 27 to 59 years at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004944 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004944">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004928"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004944</metadata:prefixIRI>
        <obo:IAO_0000115>A human child age range at vaccination with the range from the birth to one month after birth at when a vaccination is taken. HepB vaccination is sometimes taken within 12  hours after birth.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>newborn age range at human vaccination</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.cdc.gov/vaccines/parents/diseases/hepb.html</obo:IAO_0000119>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:comment>The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.</rdfs:comment>
        <rdfs:comment>https://www.cdc.gov/vaccines/vpd/vaccines-age.html</rdfs:comment>
        <rdfs:label>human age within one month at vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004987 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004987">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0005265"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018952"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005265"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004987</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 RNA vaccine formed from a lipid nanoparticle-formulated trimerized SARS-CoV-2 receptor-binding domain</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000117>Rohit Goru</obo:IAO_0000117>
        <obo:IAO_0000118>BNT162b2</obo:IAO_0000118>
        <obo:IAO_0000118>PF-07302048</obo:IAO_0000118>
        <obo:IAO_0000118>Tozinameran</obo:IAO_0000118>
        <obo:IAO_0000119>PMID: 32839784</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5784</obo:IAO_0000119>
        <obo:IAO_0000119>http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php</obo:IAO_0000119>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Tozinameran</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/Pfizer-BioNTech.html</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/pfizer-biontech-covid-19-vaccine</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/media/144246/download</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5784</obo:VO_0001818>
        <obo:VO_0003099>COMIRNATY</obo:VO_0003099>
        <obo:VO_0003160>For active immunization to prevent coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 12 years of age and older.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/151707/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125742</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Comirnaty vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004988 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004988">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004988</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>SARS-CoV-2 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004989 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004989">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004989</metadata:prefixIRI>
        <obo:IAO_0000116>Replaced term with S protein of SARS-CoV-2 Wuhan strain (PR_P0DTC2) for ontology harmonization</obo:IAO_0000116>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <rdfs:label>obsolete S protein of SARS-CoV-2</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004990 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004990">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004988"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004990</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>E protein of SARS-CoV-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004991 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004991">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005266"/>
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            </owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004991</metadata:prefixIRI>
        <obo:IAO_0000115>BBV152 (also known as Covaxin) is an inactivated COVID-19 vaccine that is developed by Bharat Biotech in collaboration with the Indian Council of Medical Research.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000117>Rohit Goru</obo:IAO_0000117>
        <obo:IAO_0000118>BBV152</obo:IAO_0000118>
        <obo:IAO_0000118>COVAXIN</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5795</obo:IAO_0000119>
        <obo:IAO_0000119>http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php</obo:IAO_0000119>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/BBV152</obo:IAO_0000119>
        <obo:IAO_0000119>https://go.drugbank.com/drugs/DB15847</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5795</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <obo:VO_0005438>502</obo:VO_0005438>
        <obo:VO_0010151>702666</obo:VO_0010151>
        <obo:VO_1000000>SARS-COV-2 COVID-19 Inactivated Virus Non-US Vaccine Product (COVAXIN)</obo:VO_1000000>
        <obo:VO_1000001>COVID-19 IV Non-US Vaccine (COVAXIN)</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>COVAXIN vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004992 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004992">
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004992</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant coronavirus-like particle SARS-CoV-2 vaccine developed by Medicago</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>CoVLP</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04636697</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5796</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5796</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <obo:VO_0005438>512</obo:VO_0005438>
        <obo:VO_0010151>778259</obo:VO_0010151>
        <obo:VO_1000000>SARS-COV-2 COVID-19 Virus Like Particle (VLP) Non-US Vaccine Product (Medicago, Covifenz)</obo:VO_1000000>
        <obo:VO_1000001>SARS-COV-2 COVID-19 VLP Non-US Vaccine (Medicago, Covifenz)</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CoVLP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004993 -->

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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004993</metadata:prefixIRI>
        <obo:IAO_0000115>A P. falciparum malaria vaccine that is formed by tull length CS-expressing replication-deficient recombinant human adenovirus 35.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:18455276</obo:IAO_0000119>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>This is a term requested by Randi for the HIPC/ImmPort work</rdfs:comment>
        <rdfs:label>Ad35.CS.01 malaria vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004994 -->

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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004994</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 trimeric S protein subunit vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>SCB-2019</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04405908</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5797</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5797</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SCB-2019 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004995 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0004958"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004995</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 S1-RBD-protein based vaccine developed by Vaxxinity</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>UB-612</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04545749</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5798</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5798</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>UB-612 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004996 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004996">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005200"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0004997"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004996</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 replication-defective human adenovirus type 5/35 vector based vaccine expressing the S protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>AdCLD-CoV19</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04666012</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5800</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5800</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AdCLD-CoV19 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004999 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0004999">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005202"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0004998"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0004999</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2-RBD-Fc fusion protein designed to induce or boost a Th1/Th2 mixed immune response in patients against the Receptor Binding Domain (RBD) of the novel coronavirus spike protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>AKS-452</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5834</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.akstonbio.com/programs/covid-19-vaccine/</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5834</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AKS-452 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005000</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCAGGSP7. This plasmid has a polylinker containing KpnI, XhoI, ClaI, EcoRV, SmaI, Not1 and Sac1 sites inserted into the EcoRI site of pCAGGS.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCAGGSP7 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID:9711802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005001</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCAGGS/MCS.  This plasmid has a chicken beta-actin promoter, contains a multiple cloning site between the EcoRI and BglII sites of the rabbit beta-globin gene, and has restriction sites for the enzymes SacI, ClaI, NsiI, Asp718, SmaI, SphI, XhoI, and NheI.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCAGGS/MCS DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 9261394</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005002</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pWRG.  This plasmid is a eukaryotic expression plasmid that contains the immediate early promoter and intron A of human cytomegalovirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pWRG DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 10403592</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005003</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pHW2000.  This plasmid is derived from pHW12 and contains part of the human pol I promoter and murine terminator sequences, a CMV promoter, and the polyadenylation signal of the gene encoding bovine growth hormone.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pHW2000 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 10662626</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005004</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCMV/R. This plasmid is a mammalian expression vector with a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV/R DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 20660192</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005005</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label VRC-9123.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>This plasmid was prepared under Good Manufacturing Practices at 4 mg/mL in phosphate buffered saline (PBS).</rdfs:comment>
        <rdfs:label>VRC-9123 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 21975270</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005006</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pPJV7563.  This plasmid has a human cytomegalovirus immediate early promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pPJV7563 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 20544035</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005007</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label p188.  This plasmid is a replication-defective derivative of pP1/H7.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>p188 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 8212843</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005008">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005008</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label VR10551.  This plasmid contains a human cytomegalovirus immediate early 1 promoter, a kanamycin resistance gene, intron A and a modified rabbit b-globin terminator.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>VR10551 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 17637571</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005009</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label VCL-1632. This plasmid contains a CMV promoter, kanamycin resistance gene, the murine Kappa constant region sequence, a translational enhancer, the murine IgG2a heavy-chain sequence, and a translation terminator. This plasmid is derived from pUC-18.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>VCL-1632 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 12384547</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005010">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005010</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pSport-B-gal.  This plasmid contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSport-B-gal DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 12496961</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005011</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pSin-B-gal.  This plasmid contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSin-B-gal DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 10646851</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005012">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005012</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pLXSHD.  This plasmid has a murine leukemia virus enhancer-promoter LTR.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pLXSHD DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 7533183</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005013</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label WRG/BEN.  This plasmid is based off of pWRG7077.  It contains a CMV promoter and a kanamycin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>WRG/BEN DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 9739060</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005014</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pNGVL4a.  This plasmid has a CMV promoter and kanamycin and ampicillin resistance genes.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>There is an extra immunostimulatory sequence (450 bp) in pNGVL4a plasmid compared to pNGVL3</rdfs:comment>
        <rdfs:label>pNGVL4a DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 11818167</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005015">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005015</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pNGVL3.  This plasmid has a CMV promoter and kanamycin and ampicillin resistance genes.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pNGVL3 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 11818167</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005016</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label SINCp B-gal.  This plasmid contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>SINCp B-gal DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 17024104</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005017</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label Synchotrope TA2M.  This plasmid is 3683 base pairs in length and has two copies of the murine CpG immune stimulatory sequence AACGTT inserted.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>It has been shown that plasmid half-life in human serum in vitro is 20 minutes</rdfs:comment>
        <rdfs:label>Synchotrope TA2M DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 12833467</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005018</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCMV/myc/ER.  This plasmid is 5066 base pairs in length and contains a CMV promoter and ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/2236/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV/myc/ER DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005019</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pPA63-LAMP1.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pPA63-LAMP1 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 19130551</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005020</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pSecTag2B.  This plasmid is 5163 base pairs in length and contains a CMV promoter and ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Invitrogen:http://tools.invitrogen.com/content/sfs/manuals/psectag2_man.pdf; Sequence: http://tools.invitrogen.com/content/sfs/vectors/psectag2b_seq.txt</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSecTag2B DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005021">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005021</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pTPA-PA63-LAMP1.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pTPA-PA63-LAMP1 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 19130551</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005022</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pTPA-PA63.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pTPA-PA63 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 19130551</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005023 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005023">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005023</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label VR2210.  This plasmid contains a CMV promoter and kanamycin resistance gene.  It was created through ligation of fragments of digested plasmid VR1012, hTPA, and B. burgdorferi B31 ospA.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>VR2210 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 8985201</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005024">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005024</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCMV-TPA/ZS7.  This plasmid contains a CMV promoter and is generated from pCMV-ZS7 by attaching hTPA to ospC ZS7.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV-TPA/ZS7 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 12941385; PMID: 10580194</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005025 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005025">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005025</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pABB-CRS2.  This plasmid is a derivative of pCVD442 and contains a chloramphenicol resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pABB-CRS2 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 11562461</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005026</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pMASIA-tgD.  This plasmid is based off of pMASIA and contains a CMV promoter and kanamycin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pMASIA-tgD DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 12466473</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005027</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCMVi-UB.  This plasmid was built from pCMV-5 and contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMVi-UB DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 10433551</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005028">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005028</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCI30.  This plasmid contains a CMV promoter, ampicillin resistance gene, T7 RNA polymerase promoter, a multiple cloning region and a 6xHis tag coding sequence.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCI30 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 17239501; PMID: 11567754</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005029</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCP15/60.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCP15/60 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005030">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005030</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pUMVC3.  This plasmid is 4030 base pairs in length and contains a CMV promoter and kanamycin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Aldevron: http://www.aldevron.com/products/dnas/umvc_expression/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pUMVC3 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 12654810</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005031">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005031</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pcDNA1.  This plasmid is 4000 base pairs in length and contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: https://www.addgene.org/vector-database/2089/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcDNA1 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005032">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005032</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCAT.  This plasmid is 4364 base pairs in length and contains an ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/2051/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCAT DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005033</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pGT36.  This plasmid is a derivative of pcDNA3 and contains a CMV promoter and a kanamycin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pGT36 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 9569471]</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005034</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label VR1040.  This plasmid contains four copies of the mouse immunostimulatory sequence and is similar to VR1012.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>VR1040 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 11883007</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005035">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005035</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pcTPA.  This plasmid is based on pcDNA3 and contains the hTPA signal sequence.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcTPA DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 16122850</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005036</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pMV10.1.  This plasmid contains a CMV promoter and a kanamycin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pMV10.1 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 16125280</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005037 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005037">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005037</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pET11d.  This plasmid is 5674 base pairs in length and contains an ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/2628/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pET11d DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 16520093</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005038">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005038</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pUMVC4b.  This plasmid is 4478 base pairs in length and contains a CMV promoter and kanamycin and ampicillin resistance genes.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Aldevron: http://www.aldevron.com/products/dnas/umvc_expression/; Sequence: https://system.netsuite.com/c.606687/pUMVC4a.txt</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pUMVC4b DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005039 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005039">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005039</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pRC.  This plasmid is 7400 base pairs in length and contains CMV and RSV promoters.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pRC DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 9879611</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005040</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pAK-4.  This plasmid is 6600 base pairs in length and contains a CMV promoter and kanamycin and ampicillin resistance genes.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pAK-4 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 16157425</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005041">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005041</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCMVi(-H3)Ubs.  This plasmid contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMVi(-H3)Ubs DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 10438054</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005042">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005042</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label Auxo-GTU.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>patent applications, PCT/FI02/00379 filed 03.05.2002 and PCT/FI2004/ 000540 filed 15.09.2004</rdfs:comment>
        <rdfs:label>Auxo-GTU DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 16359234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005043">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005043</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCMN160.  This plasmid has a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMN160 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 9142121</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005044">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005044</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label V1Jns.  This plasmid contains the human CMV promoter, enhancer and intron A as well as the polyadenylation sequences of bovine growth hormone.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>V1Jns DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 9127013</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005045">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005045</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pND-14.  This plasmid contains a CMV promoter, ampicillin resistance gene, a tissue plasminogen activator leader sequence, a bovine growth hormone terminator, and constitutive transport element from simian retrovirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pND-14 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 15149785</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005046">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005046</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pSecTag2A.  This plasmid is 5159 base pairs in length and contains a CMV promoter and ampicillin reisistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Invitrogen: http://tools.invitrogen.com/content/sfs/manuals/psectag2_man.pdf; Sequence: http://tools.invitrogen.com/content/sfs/vectors/psectag2a_seq.txt</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSecTag2A DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005047</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pRc/CMV-HBs(S).  This plasmid is 5618 base pairs in length and contains a CMV promoter and ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Bioresearch Online: http://www.bioresearchonline.com/doc/pRcCMV-HBsS-0001</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Also known as pCMV-S</rdfs:comment>
        <rdfs:label>pRc/CMV-HBs(S) DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005048 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005048">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005048</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pcDNA.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcDNA DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 15839423</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005049">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005049</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label proVAX. This plasmid contains a CMV promoter and a hCG-beta leader sequence.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>proVAX DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 17310492</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005050</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label p1012.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>p1012 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 11117750</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005051</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pUSE-.  This plasmid is a mammalian expression vector derived from pCI-neo.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pUSE- DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 11507187</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005052 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005052">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005052</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label APL023.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>APL023 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 17241713</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005053 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005053">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005053</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pEGFP-N1.  This plasmid is 4733 base pairs in length and contains a CMV promoter and kanamycin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/2491/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pEGFP-N1 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005054</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCDL-SRa296.  This plasmid is 3700 base pairs in length and contains a SRalpha promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/2084/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCDL-SRa296 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 2827008</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005055">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005055</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pUSK.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pUSK DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 15121294</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005056 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005056">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005056</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pUBIQ.  This plasmid is derived from pGEM3 and contains a CMV promoter and an ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pUBIQ DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 12922097</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005057 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005057">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005057</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1/Hygro(-).  This plasmid is 5596 base pairs in length and contains a CMV promoter and an ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/2105/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Differs from other pcDNA3.1 in drug resistance; +/- refers to orientation of f1 ori</rdfs:comment>
        <rdfs:label>pcDNA3.1/Hygro(-) DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005058 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005058">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005058</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCMV3ISS.  This plasmid is a eukaryotic expression vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV3ISS DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 18951941</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005059 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005059">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005059</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pWRG7079.  This plasmid contains a CMV promoter and a kanamycin resistance gene and differs from pWRG7077 by the insertion of a TPA sequence.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pWRG7079 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 12922144</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005060">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005060</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pVR1020.  This plasmid contains a CMV promoter and kanamycin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pVR1020 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 11292786</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005061">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005061</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label nkCMVintpolyli.  This plasmid contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>nkCMVintpolyli DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 8666931</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005062">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005062</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1/V5-His-TOPO.  This plasmid is 5523 base pairs in length and contains a CMV promoter and ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/5587/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcDNA3.1/V5-His-TOPO DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005063 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005063">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005063</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pIRES1neo.  This plasmid is 5257 base pairs in length and contains an ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Metalife: http://www.metalife.com/Genbank/1899169</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pIRES1neo DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005064">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005064</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pRc/RSV.  This plasmid is 5224 base pairs in length and contains a RSV LTR promoter and ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/3908/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pRc/RSV DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005065 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005065">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005065</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCI-TPA.  This plasmid contains the N-terminal signal sequence of TPA.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCI-TPA DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 19428891</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005066">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005066</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCSIVgag.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCSIVgag DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 18000037</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005067 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005067">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005067</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pVacc4.  This plasmid is a derivative of pVacc1 and contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pVacc4 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 15004179</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005068 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005068">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005068</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pBC12B1.  This plasmid is a eukaryotic expression vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pBC12B1 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 10948115</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005069 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005069">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005069</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pGFP.  This plasmid is 3300 base pairs in length and contains a lac promoter and an ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Clontech: http://www.clontech.com/xxclt_ibcGetAttachment.jsp?cItemId=17740</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pGFP DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005070 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005070">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005070</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pCMV-beta.  This plasmid is 7164 base pairs in length and contains a CMV promoter and ampicllin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/2245/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pCMV-beta DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005071 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005071">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005071</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pSW3891.  This plasmid contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pSW3891 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 16919703</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005072 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005072">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005072</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pJW4304.  This plasmid is 5132 base pairs in length and contains a CMV promoter.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>NIH AIDS Reagent Program: https://www.aidsreagent.org/reagentdetail.cfm?t=cloning_vectors&amp;id=76</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pJW4304 DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005073">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005073</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pGT146-mIL-12.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pGT146-mIL-12 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 18694965</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005074 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005074">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005074</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pDNAVACC.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pDNAVACC DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 21134447</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005075">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005075</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label VR1055.  This plasmid is derived from pUC19 and contains a CMV promoter, kanamycin resistance gene, a cloning polylinker, and a transcriptional terminator region derived from the rabbit beta-globin gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>VR1055 DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 9990062</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005076</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pRSC.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pRSC DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 21185849</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005077 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005077">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005077</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1(Zeo)+.  This plasmid is 5015 base pairs in length and contains a zeocin selectable marker, a CMV promoter, and an ampicillin resistance gene.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>Addgene: http://www.addgene.org/vector-database/2110/</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>pcDNA3.1(Zeo)+ DNA vaccine plasmid</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005078 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005078">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000435"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005078</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine plasmid vector that has the plasmid label pVF.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:comment>Also known as pVAX-Flag</rdfs:comment>
        <rdfs:label>pVF DNA vaccine plasmid</rdfs:label>
        <rdfs:seeAlso>PMID: 23026687</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005079 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005079">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005199"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005079</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 vaccine consisting of autologous dendritic cells previously loaded ex vivo with spike protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>AV-COVID-19</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04386252</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5801</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5801</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AV-COVID-19 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005081 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005081">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005269"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005081</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 vaccine that includes a protein antigen, SARS-CoV-2 Spike RBD, adsorbed to the adjuvant Alhydrogel (Alum), in combination with another approved adjuvant, CpG 1018</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>Corbevax</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5802</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.biologicale.com/news.html</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5802</obo:VO_0001818>
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        <obo:VO_1000000>SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (EpiVacCorona)</obo:VO_1000000>
        <obo:VO_1000001>COVID-19 PS Non-US Vaccine (EpiVacCorona)</obo:VO_1000001>
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    <!-- http://purl.obolibrary.org/obo/VO_0005089 -->

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        <obo:IAO_0000115>A SARS-CoV-2 plasmid DNA vaccine developed by GeneOne Life Science.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005090 -->

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        <obo:IAO_0000115>A rVSV-SARS-CoV-2-S vaccine developed by the Israel Institute for Biological Research (IIBR).</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IIBR-100 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005091 -->

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        <obo:IAO_0000115>A SARS-CoV-2 recombinant vector vaccine by Shenzhen Geno-Immune Medical Institute</obo:IAO_0000115>
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        <rdfs:label>LV-SMENP-DC vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005092 -->

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        <rdfs:label>Nanocovax vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005093 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005094 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005096 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005097 -->

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        <obo:IAO_0000115>A SARS-CoV-2 subunit vaccine developed by Finlay Vaccine Institute (IFV)</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005098 -->

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        <obo:IAO_0000115>A SARS DNA combination vaccine that is made from recombinant plasmids&apos; containing membrane protein (M) and nucleocapsid protein (N) sequences constructed then expressed and purified from E. coli bacteria.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16423399</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS N + SARS M DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005102 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005102</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS  DNA vaccine that is made from recombinant plasmid containing membrane protein (M) sequence constructed then expressed and purified from E. coli bacteria.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16423399</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS M protein DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005103">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005103</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS DNA vaccine that is made from oral live-attenuated auxotrophic S. typhimurium aroA strain SL7207 that contained CTLA4HingeSARS800 with SARS-CoV S protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15993989</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella-CTLA4-S SARS DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005104">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005104</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS DNA vaccine that is made from  intraperitoneal recombinant spike polypeptide generated by amplififying gene encoding amino acids residues 14-667 of S protein that was cloned BamHI and KpnI sites of vector pQE-31 that was generated by Escherichia coli</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15993989</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5734</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>5734</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Recombinant SARS spike polypeptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005105 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005105">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005105</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS DNA vaccine that is made from  CTLA4HingeSARS800 DNA with SARS-CoV S protein</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15993989</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS CTLA4-S DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005106 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005106">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005106</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS DNA vaccine that is made from tpa-optimize800 DNA with SARS-CoV S protein</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15993989</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS tPA-S DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005107 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005107">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005107</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS DNA vaccine made from  CTLA4HingeSARS800 DNA with SARS-CoV S protein</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15993989</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Salmonella-tPA-S SARS DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005108 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005108">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005108</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS recombinant vector vaccine that is made  from of the highly attenuated modified vaccinia virus Ankara (MVA) containing the gene encoding full-length SARS-CoV S</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:23142821</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5729</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5729</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS MA-ExoN vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005109 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005109">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005109</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS recombinant vector vaccine that is made from  recombinant MA15 virulent mouse-adapted SARS-CoV (MA15) background of E-deleted vaccine candidate  (rMA15-DeltaE).</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16423399</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5728</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5728</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS rMA15-ΔE vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005110 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005110">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005110</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS recombinant vector vaccine that is made from a recombinant live-attenuated modified vaccinia virus Ankara (MVA) that had a full-length SARS-CoV envelope Spike (S) glycoprotein gene introduced into the deletion III region of the MVA genome.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15708987</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5726</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5726</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS ADS-MVA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005111 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005111">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005111</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS subunit vaccine that has a combined adjuvant of aluminum hydroxide and CpG oligodeoxynucleotides.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29618723</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5714</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5714</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS-CoV S vaccine adjuvanted with CpG and Alum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005112 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005112">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005112</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS inactivated whole virus vaccine that has a combined adjuvant that has a combined adjuvant of aluminum hydroxide and CpG oligodeoxynucleotides.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29618723</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5721</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001818>5721</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Inactivated whole MERS-CoV (IV) vaccine with CpG and Alum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005113 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005113</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS recombinant vector vaccine made from a recombinant form of the highly attenuated modified vaccinia virus Ankara (MVA) containing the gene encoding full-length SARS-CoV S</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15096611</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5725</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5725</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS MVA/S vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005114 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005114">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005114</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS inactivated vaccine made from whole killed (inactivated by beta-propiolactone) SARS-CoV</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16476986</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5730</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001818>5730</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>beta-propiolactone-inactivated SARS-CoV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005115 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005115">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005115</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS recombinant vector vaccine made of combination of two adenovirus-based vectors, one expressing the nucleocapsid (N) and the other expressing the spike (S) protein</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16476986</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS Ad S/N vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005116 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005116">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005116</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS recombinant vector vaccine made of a recombinant adenoviral vector encoding the  the S1 extracellular domain of S protein</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:25192975</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5720</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>5720</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ad5.MERS-S1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005117 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005117">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005117</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS recombinant vector vaccine made of a recombinant adenoviral vector encoding the full-length MERS-CoV S protein (Ad5.MERS-S)</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:25192975</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5719</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0001081"/>
        <obo:VO_0001818>5719</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ad5.MERS-S vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005118 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005118">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005118</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS DNA vaccine made of plasmid  that encoded S1 subunit only</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26218507</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5716</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>5716</obo:VO_0001818>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS England1 S1 protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005119</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS combination vaccine made of made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein and a DNA vaccine that is a plasmid  that encoded S1 subunit</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26218507</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5717</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001818>5717</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS England1 S DNA + England1 S protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005120</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS DNA vaccine made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26218507</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5715</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>5715</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS England1 S DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005121">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005121</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS subunit vaccine made of neutralizing monoclonal antibodiesagainst MERS-CoV which bind to the ribosomal binding domain (RBD) of the MERS-CoV S protein that was expressed by baculovirus-insect cell sf9-derived recombinant MERS-CoV.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS rRBD plus alum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005122 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005122</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS DNA vaccine made of plasmid that encodes the first 725 amino acids of S from MERS-CoV</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:28314561</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5718</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>5718</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS-CoV pcDNA3.1-S1 DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005123 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005123">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005123</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS recombinant vector virus made from chimeric virus based on the vesicular stomatitis virus (VSV) in which the G gene was replaced by MERS-CoV S gene (VSV≈í√ÆG-MERS).</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29246504</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5722</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5722</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VSVΔG-MERS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005124 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005124">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005124</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS subunit vaccine made of a neutralizing monoclonal antibodiesagainst MERS-CoV which bind to the N-terminal domain (NTD) of the MERS-CoV S1 subunit that was expressed by baculovirus-insect cell sf9-derived recombinant MERS-CoV.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:28536429</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS rNTD vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005125 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005125">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005125</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS inactivated vaccine made from inactivated whole virus by formalin and Ultraviolet radiation, hence Double Inactivated (DI) Vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22536382</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5742</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001818>5742</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated whole (formalin and UV radiation) SARS-CoV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005126 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005126">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005126</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant SARS DNA vaccine made from rDNA-expressed ectodomain of the S protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22536382</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5743</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001818>5743</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant SARS DNA spike protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005127 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005127">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004914"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005127</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS VLP vaccine made from the SARS-CoV spike protein (S) and the Nucleocapsid (N), envelope (E) and membrane (M) proteins from mouse hepatitis coronavirus (MHV)</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22536382</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Viral-like-particle S-MHV SARS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005128 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005128">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005128</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS inactivated vaccine made from SARS-CoV inactivated by ultraviolet radiation and a Toll-Like Receptor Agonist Adjuvant is added to prevent eosinophilic immunopathology</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22536382</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>UV-Inactivated SARS + TLR agonist vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005129 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005129">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005129</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS inactivated vaccine made from SARS-CoV inactivated by ultraviolet radiation</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22536382</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>UV-Inactivated SARS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005130 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005130">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005130</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS recombinant vector made from Venezuelan equine encephalitis replicons bearing epitopes of N protein from MERS. Crosslisted as SARS vaccine (VIOLINID:5754). Efficacy higher intranasally than subcutaneously.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26954467</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5748</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5754</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5748</obo:VO_0001818>
        <obo:VO_0001818>5754</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VRP-MERS-N vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005131 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005131">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005131</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS recombinant vector vaccine made from Venezuelan equine encephalitis replicons (VRP) encoding a SARS-CoV CD4+ T cell epitope vaccinated intranasally. Crosslisted as MERS vaccine (VIOLINID:5789). Efficacy higher intranasally than subcutaneously.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26954467</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5749</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5755</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5749</obo:VO_0001818>
        <obo:VO_0001818>5755</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VRP-SARS-N vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005132 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005132">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005132</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS DNA vaccine made of plasmid vaccines that encoded S1 subunit only</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26954467</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rVV-SARS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005133 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005133">
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005133</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS recombinant vector vaccine made of live-attenuated measles virus (MV) vaccine encoding the MERS-CoV spike protein (MERS-S).</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26355094</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVvac2-MERS-S(H) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005134 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005134">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005134</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS recombinant vector vaccine made of live-attenuated measles virus (MV) vaccine encoding the MERS-CoV nucleocapsid protein (MERS-N).</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29902727</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVvac2-MERS-N vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005135 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005135">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005181"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005135</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS recombinant vector made of  Chimpanzee adenovirus Oxford 1 vector expressing S protein from MERS-CoV.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29263883</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5751</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0005181"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5751</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ChAdOx1-MERS-S vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005136 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005136">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005136</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS recombinant vector made of Adenovirus type 41 used as vector for MERS-CoV S protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:25762305</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ad41.MERS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005137 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005137">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005137</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS VLP vaccine made from  a recombinant baculovirus co-expresssing the spike S, envelope (E), and membrane (M) proteins of MERS.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:23986586</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVA-MERS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005138 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005138">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005138</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS DNA vaccine made from  encoding calrectulin linked to a SARS-CoV N protein</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15078946</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CRT-N SARS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005139 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005139">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005139</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS recombinant vector vaccine made from a line attenuated and recombinant SARS-CoV lacking the E gene</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:18463152</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rSARS-CoV-ΔE vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005140 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005140">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005140</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS recombinant vector made of MVvac2 (measle virus) expressing a soluble, truncated version of spike glycoprotein of MERS-CoV in its full length cloned into the MVvac2 genome and rescued.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26355094</obo:IAO_0000119>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MVvac2-MERS-solS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005141 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005141">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005266"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005141</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 whole virus vaccine made from a purified inactivated SARS-CoV-2 virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000117>Rohit Goru</obo:IAO_0000117>
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        <obo:IAO_0000118>PiCoVacc</obo:IAO_0000118>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5761</obo:IAO_0000119>
        <obo:IAO_0000119>http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php</obo:IAO_0000119>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/CoronaVac</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
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        <obo:VO_0001818>5761</obo:VO_0001818>
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        <obo:VO_0005438>511</obo:VO_0005438>
        <obo:VO_0010151>702673</obo:VO_0010151>
        <obo:VO_1000000>SARS-COV-2 COVID-19 Inactivated Virus Non-US Vaccine Product (CoronaVac, Sinovac)</obo:VO_1000000>
        <obo:VO_1000001>COVID-19 IV Non-US Vaccine (CoronaVac, Sinovac)</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CoronaVac vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005142 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005142">
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005142</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 subunit vaccine composed of the SARS-CoV-2 S protein receptor-binding domain produced in Chinese hamster ovary (CHO) cells and adjuvant aluminum hydroxide.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
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        <obo:IAO_0000119>http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php</obo:IAO_0000119>
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        <obo:VO_0001818>5764</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ZF2001 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005143 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005179"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005143</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 RNA vaccine made of self-coding RNA encoding SARS-CoV-2 spike protein encapsulated within a lipid nanoparticle.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>LNP-nCoVsaRNA</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:32647131</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5771</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0005179"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5771</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>LNP-nCoVsaRNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005144 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005144</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 vaccine made from a recombinant adinvorius type-5 expressing SARS-CoV-2 S protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>Ad5-nCoV</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:32450106</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5768</obo:IAO_0000119>
        <obo:IAO_0000119>http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0001081"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5768</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ad5-nCoV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005145 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005145">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004900"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005145</metadata:prefixIRI>
        <obo:IAO_0000115>A MERS DNA Vaccine that is made of the plasmid pGX9109 expressing MERS S protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:32450106</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5769</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5769</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1335626"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MERS GLS-5300 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005146</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS DNA vaccine made of a single closed plasmid DNA marcromolecule (VRC-8138) that produces a deletion mutant of the SARS Spike glycoprotein</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:18824060</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5770</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5770</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VRC-SRSDNA015-00-VP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005147 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005147</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV recombinant vector vaccine that is made from the Newcastle disease virus from the mesogenic Beaudette C strainexpressing SARS-CoV S protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17535926</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5766</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5766</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS NDV-BC/S vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005148 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005148">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005148</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV recombinant vector vaccine that is made from the Newcastle disease virus from  the lentogenic LaSota strain expressing SARS-CoV S protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17535926</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5767</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5767</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9534"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS NDV-VF/S vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005149 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005149">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005149</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS DNA vaccine made from rDNA-expressed ectodomain of the S protein.</obo:IAO_0000115>
        <obo:IAO_0000116>JZ: may be same as VO:0005126</obo:IAO_0000116>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16497416</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5745</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5745</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rDNA-expressed S SARS protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012183"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005150</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS DNA vaccine made up of arecombinat vector vaccine made from recombinant measles virus expressing S protein and recombinant measles virus expressing N protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:18346823</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5762</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>5762</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rMV-S + rMV-N vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005151 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005152 -->

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        <obo:IAO_0000115>A MERS recombinant vector made of recombinant modified vaccinia virus Ankara (rMVA) vaccine vector carrying full MERS-CoV spike glycoprotein.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005153 -->

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        <obo:IAO_0000115>A SARS-CoV-2 single dose intranasal vaccine manufactured by Altimmune in collaboration with the University of Alabama-Birmingham. This vaccine was discontinued after a Phase 1 trial.</obo:IAO_0000115>
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        <rdfs:label>AdCOVID vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005154 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005155 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005156 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005157 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005164 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005165 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005166 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005168 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005170 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005171 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005173</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 protein subunit vaccine developed by Adimmune Corporation. AdimrSC-2f is a candidate vaccine against COVID-19 developed by Adimmune Corporation (Adimmune). Using the baculovirus-insect cells expression system, the recombinant receptor binding domain (RBD) of SARS-CoV-2 spike (S) protein is amplified and purified. AdimrSC-2f is formulated in the different dosages of Spike (S) protein without/with aluminum content as adjuvant.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>AdimrSC-2f</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04522089</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5873</obo:IAO_0000119>
        <obo:IAO_0000119>https://go.drugbank.com/drugs/DB16436</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.smartpatients.com/trials/NCT04522089</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>5873</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AdimrSC-2f vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005174 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005174</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 oral DNA vaccine that delivers plasmids containing synthetic DNA encoding spike protein from SARS-CoV-2.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>bacTRL-Spike</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04334980</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5817</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.symvivo.com/covid-19</obo:IAO_0000119>
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        <obo:VO_0001818>5817</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bacTRL-Spike vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005175 -->

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            </owl:Restriction>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005175</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 mRNA vaccine manufactured by Chulalongkorn University</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>ChulaCov19</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04566276</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5818</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5818</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ChulaCov19 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005176 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005176">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005176</metadata:prefixIRI>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>A synthetic modified vaccinia Ankara (MVA)-based SARS-CoV-2 vaccine.</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0005394"/>
        <rdfs:label>obsolete COH04S1</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005177 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005177</metadata:prefixIRI>
        <obo:IAO_0000115>an adenovirus vaccine vector that uses a gorilla adenovirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>gorilla adenovirus vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005178">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000136"/>
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        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>adenovirus serotype 26 vaccine vector</rdfs:label>
        <rdfs:seeAlso>NCBI Taxonomy ID: 46928</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005179 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005179</metadata:prefixIRI>
        <obo:IAO_0000115>A nanoparticle vector composed of lipids.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 20402623</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>lipid nanoparticle vector</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005180 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005180">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003674"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005180</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine vector that is a tiny particle, typically in the nanometer size range, used to deliver genetic code to specific cells within the body.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID: 22353619</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>nanoparticle vector</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005181">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005181</metadata:prefixIRI>
        <obo:IAO_0000115>A chimpanzee adenovirus vaccine vector that  patented by Oxford and derived from ChAd serotype Y25 that exchanges the native E4 orf4, orf6 and orf6/7 genes for those from HAdV-C5</obo:IAO_0000115>
        <obo:IAO_0000119>PMID: 29527232</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>chimpanzee adenovirus Oxford1 vaccine vector</rdfs:label>
        <rdfs:seeAlso>ChAdOx1</rdfs:seeAlso>
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    <!-- http://purl.obolibrary.org/obo/VO_0005182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005182">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005182</metadata:prefixIRI>
        <obo:IAO_0000115>A chimpanzee adenovirus vaccine vector developed by Oxford by deleting E1/E3  from ChAd68 with a modified E4 region.</obo:IAO_0000115>
        <obo:IAO_0000119>PMID: 29527232</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>chimpanzee adenovirus Oxford2 vaccine vector</rdfs:label>
        <rdfs:seeAlso>ChAdOx2</rdfs:seeAlso>
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    <!-- http://purl.obolibrary.org/obo/VO_0005183 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005183</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 DNA vaccine developed by Providence Health &amp; Services.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>CORVax12</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04627675</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5820</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>5820</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CORVax12 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005184 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005184</metadata:prefixIRI>
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        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>IMP CoVac-1</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0005191 -->

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        <obo:IAO_0000115>A SARS-CoV-2 recombinant vector vaccine that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein (S)</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005192 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005193 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005194 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005195 -->

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        <rdfs:label>V590 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005196 -->

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        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0005197 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005198 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>COVID-19 RNA vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005199 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0005200 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0005201 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>COVID-19 inactivated vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005203 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005204 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005205 -->

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        <rdfs:label>COVID-19 virus-like particle vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005206 -->

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        <obo:IAO_0000115>A saponin vaccine adjuvant comprised of 40 nm nanoparticles composed of Quillaja saponins, cholesterol and phospholipid.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22844480</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0005207 -->

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        <obo:IAO_0000115>A carbohydrate vaccine adjuvant derived from delta inulin</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Carbohydrate
Mechanism of Action: Complement, Dendritic cells (unknown receptor), Other, Unknown
Immune profile induced: mixed Th1/Th2
By routes: IM, IN, IP, SQ, inhalation,
Point of Contact: Nikolai Petrovsky, Vaxine
https://www.ncbi.nlm.nih.gov/pubmed/?term=31009889
https://www.ncbi.nlm.nih.gov/pubmed/?term=25520500
https://www.ncbi.nlm.nih.gov/pubmed/?term=28758637
https://www.ncbi.nlm.nih.gov/pubmed/?term=23864620
https://www.ncbi.nlm.nih.gov/pubmed/?term=24342245
https://www.ncbi.nlm.nih.gov/pubmed/?term=23306367
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        <obo:IAO_0000115>A SARS-CoV-2 plasmid DNA vaccine manufactured by Takis and Rottapharm Biotech</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005231 -->

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        <obo:IAO_0000115>A SARS-CoV-2 DNA vaccine manufactured by University of Sydney, Bionet Co., and Technovalia</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005232 -->

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        <obo:IAO_0000115>A SARS-CoV-2 protein subunit vaccine by EuBiologics Co., Ltd.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005233 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005234 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005235 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005236 -->

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        <obo:IAO_0000115>A SARS-CoV-2 mRNA vaccine by Providence Therapeutics</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005237 -->

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        <obo:IAO_0000115>A SARS-CoV-2 protein subunit vaccine manufactured by Walter Reed Army Institute of Research</obo:IAO_0000115>
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        <rdfs:label>SpFN vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005238 -->

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        <obo:IAO_0000115>A SARS-CoV-2 virus-like particle vaccine that expresses a modified version of the SARS-CoV-2 spike (S) glycoprotein and is equipped with an aluminum phosphate adjuvant. It is manufactured by VBI Vaccines Inc. and is delivered intramuscularly.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>VBI-2902a vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005239 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005239</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 inactivated vaccine developed by Organization of Defensive Innovation and Research in Iran</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>FAKHRAVAC vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005240 -->

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        <obo:IAO_0000115>A SARS-CoV-2 live, attenuated vaccine manufactured by Meissa Vaccines, Inc. that expresses the spike (S) protein of SARS-CoV-2.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MV-014-212 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005241 -->

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        <rdfs:label>MRT5500 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005243 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005243</metadata:prefixIRI>
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    <!-- http://purl.obolibrary.org/obo/VO_0005244 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005256 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005257 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005258 -->

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        <rdfs:label>MF59-adjuvanted SARS-CoV-2 Sclamp vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005259 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005260 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005261 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005262 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005263 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005264 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005265 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005266 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005267 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005268 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000115>A vaccine adjuvant that includes IV270, which is a low-molecular weight TLR7 agonist conjugated to a phospholipid and is a highly potent and stable immune activator.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Receptor: TLR7
Mechanism of Action: Activation of innate immune pathways
Immune profile induced: Th1-biased
Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces CD8 T cells, (3) Induces epitope spreading, (4) Provides innate protection, (5) Promotes antibody affinity maturation, (6) Promotes antibody epitope spreading By routes: intramuscular and intranasal.
Point of Contact: Dennis Carson, UCSD</obo:IAO_0000116>
        <obo:IAO_0000117>Dennis Carson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>1V270</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:25568203</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:28724768</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:32636840/</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=6</obo:IAO_0000119>
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        <obo:VO_0005328>6</obo:VO_0005328>
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    <!-- http://purl.obolibrary.org/obo/VO_0005271 -->

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        <obo:IAO_0000116>Chemical Nature: Small molecule
Receptor: TLR4
Mechanism of Action: Innate immune activation
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: (1) Induces mucosal immunity, (2) Anti-inflammatory, (3) Promotes antibody epitope spreading. By routes: intramuscular and intranasal.
Point of Contact: Dennis Carson, UCSD</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Dennis Carson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>2B182C</obo:IAO_0000118>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=25568203</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28724768</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32636840</obo:IAO_0000119>
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        <obo:VO_0005328>7</obo:VO_0005328>
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    <!-- http://purl.obolibrary.org/obo/VO_0005272 -->

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        <obo:IAO_0000115>A role of a material entity that binds to TLR7 and activates the receptor for pathogen recognition and activation of innate immunity.</obo:IAO_0000115>
        <obo:IAO_0000116>TLR7 agonist role</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>https://en.wikipedia.org/wiki/TLR7</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0005273 -->

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        <obo:IAO_0000115>A SARS-CoV-2 protein subunit vaccine manufactured by the Research Institute for Biological Safety Problems in Kazakhstan</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>QazCoVac-P</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04930003</obo:IAO_0000119>
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        <obo:VO_0001818>5874</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0005274 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005275 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005276 -->

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        <obo:IAO_0000115>A SARS-CoV-2 self-amplifying RNA vaccine sponsored by MRC/UVRI and LSHTM Uganda Research Unit</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>LNP-nCOV saRNA-02</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04934111</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5875</obo:IAO_0000119>
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        <obo:VO_0001818>5875</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>LNP-nCOV saRNA-02 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005277 -->

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        <obo:IAO_0000115>A multivalent SARS-CoV-2 mRNA booster vaccine which combines mRNA-1273, Moderna&apos;s authorized vaccine against ancestral strains, and mRNA-1273.351 in a single vaccine at the 50 ug dose level and lower.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
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        <obo:IAO_0000119>https://investors.modernatx.com/news-releases/news-release-details/moderna-announces-it-has-shipped-variant-specific-vaccine</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0005179"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5876</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>mRNA-1273.211 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005278">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005278</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5304</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/77</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5304</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>(H115D)VHL35 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005281">
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005281</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Receptor: Dendritic cells (unknown receptor)
Mechanism of Action: Innate immune activation
Immune profile induced: Th1-biased
Other Features/Characteristics: Other. Specify: Co-adjuvant for TLR4 ligands
Point of Contact: Dennis Carson, UCSD</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Dennis Carson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>2E151</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=9</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>9</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>2E151 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005282 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005282">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005313"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005282</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Receptor: CLR (Dectin, Mincle)
Mechanism of Action: None/Unknown
Immune profile induced: Th17-component
Other Features/Characteristics: None
Point of Contact: Kendal Ryter, U. Montana &amp; Inimmune</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Kendal Ryter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>UM-1098</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=27</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005313"/>
        <obo:VO_0005328>27</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>UM-1098 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005283 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005283">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005283</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Small molecule and Synthetic derivative of natural compound
Receptor: Unknown and NLRP3
Mechanism of Action: Presumably the same as QS-21 in the absence of dose-limiting toxicity
Immune profile induced: Th1-biased
Other Features/Characteristics: None
Point of Contact: Melissa Malhame, Adjuvance Technologies</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Melissa Malhame</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>TQL-1055</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=36</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>36</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>TQL-1055 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005284 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005284">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005307"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005314"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005284</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Emulsion
Receptor: TLR2 and TLR4
Mechanism of Action: Activation of mucosal and systemic immunity
Immune profile induced: Th1/Th17
Other Features/Characteristics: Promotes antibody affinity maturation
Point of Contact: Ali Fattom, BlueWillow Biologics</obo:IAO_0000116>
        <obo:IAO_0000117>Ali Fattom</obo:IAO_0000117>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>NanoVax/NE01</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=22</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=31495593</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=31515143</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005307"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005314"/>
        <obo:VO_0005328>22</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>NanoVax/NE01 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005285 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005285">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005285</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Other
Receptor: TLR4
Mechanism of Action: TLR4 agonist
Immune profile induced: Th1-biased
Other Features/Characteristics: None/Unknown
Point of Contact: Darrick Carter, PAI Life Sciences</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Darrick Carter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>MiT4</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=16</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>16</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>MiT4 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005286 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005286">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005286</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: (1) Natural compound, (2) Carbohydrate, (3) Combination adjuvant
Receptor: CLR (Dectin, Mincle) and NAIP
Mechanism of Action: Activation of Dectin-2-expressing innate immune cells; dual targeting of injection site and draining lymph node.
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: Promotes antibody epitope spreading
Point of Contact: Ivan Zanoni, Boston Children&apos;s Hospital</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Ivan Zanoni</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=14</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>14</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Mannadjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005287 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005287">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005287</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Combination Adjuvant
Receptor: TLR4
Mechanism of Action: TLR4 agonist plus potential inflammasome
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: None/Unknown
Point of Contact: Darrick Carter, PAI Life Sciences</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Darrick Carter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>LiT4</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=20</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>20</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>LiT4 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005288 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005288">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005272"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005306"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005288</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Receptor: TLR7 and TLR8
Mechanism of Action: None/Unknown
Immune profile induced: Th1-biased
Other Features/Characteristics: None
Point of Contact: Kendal Ryter, U. Montana &amp; Inimmune</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Kendal Ryter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>INI-4001</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=28</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005272"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005306"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>28</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>INI-4001 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005289 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005289">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005289</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Receptor: TLR4
Mechanism of Action: None/Unknown
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: None
Point of Contact: Kendal Ryter, U. Montana &amp; Inimmune</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Kendal Ryter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>INI-2004</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=26</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>26</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>INI-2004 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005290 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005290</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Receptor: TLR4
Mechanism of Action: None/Unknown
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: None
Point of Contact: Kendal Ryter, U. Montana &amp; Inimmune</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Kendal Ryter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>INI-2002</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=29</obo:IAO_0000119>
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        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>29</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>INI-2002 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005291 -->

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        <obo:IAO_0000116>Chemical Nature: Small molecule and Combination adjuvant
Receptor: TLR4 and TLR7
Mechanism of Action: Activation of antigen presenting cells and stimulating B cell proliferation
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces CD8 T cells, (3) Induces epitope spreading, (4) Provides innate protection, (5) Promotes antibody epitope spreading. By routes: intramuscular and intranasal.
Point of Contact: Dennis Carson, UCSD</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Dennis Carson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Fos47</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=5</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=25568203</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28724768</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32636840</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005272"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>5</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Fos47 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005292">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005292</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Emulsion
Receptor: TLR4
Mechanism of Action: Squalene emulsion plus TLR4
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: None
Point of Contact: Darrick Carter, PAI Life Sciences</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Darrick Carter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>EmT4</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=17</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>17</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>EmT4 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005293 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005293">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001355"/>
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        <obo:IAO_0000116>Chemical Nature: Emulsion
Receptor: Unknown
Mechanism of Action: Squalene emulsion possibly triggering inflammasome or through extracellular ATP
Immune profile induced: None
Other Features/Characteristics: None
Point of Contact: Darrick Carter, PAI Life Sciences</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Darrick Carter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Em</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=18</obo:IAO_0000119>
        <obo:VO_0005328>18</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Em vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005294 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005294">
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            </owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005294</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: (1) Synthetic derivative of natural compound, (2) Nucleic acid
Receptor: TLR3
Mechanism of Action: TLR3, possibly RIG-I - agonist
Immune profile induced: Th1-biased
Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces CD8 T cells, (3) Provides innate protection. By routes: SQ, IM.
Point of Contact: Carolina Lopez, University of Washington at St Louis</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Carolina Lopez</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>DDO</obo:IAO_0000118>
        <obo:IAO_0000118>DDO (Defective viral genome-Derived Oligonucleotide)</obo:IAO_0000118>
        <obo:IAO_0000118>Defective viral genome-Derived Oligonucleotide</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=30</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24099876</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=29861183</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005305"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>30</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>defective viral genome-derived oligonucleotide vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005295 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005295">
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        <obo:IAO_0000116>Chemical Nature: Synthetic derivative of natural compound
Receptor: Unknown
Mechanism of Action: (1) Antigen carrier, (2) Innate immune enhancer/activator
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces CD8 T cells, (3) Provides innate protection, (4) Other, (5) Promotes antibody affinity maturation, (6) High stability. By routes: IM, IN, IP, IN, ID, IVag. Specify: Safe for systemic or mucosal administration
Point of Contact: Tulin Morcol, Captivate Pharma</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Tulin Morcol</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>CaPNP (CaPtivant)(TM)</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=11</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=11063495</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=12204953</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28716554</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28933657</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=31591662</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>11</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>CaPNP (CaPtivant)(TM) vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005296 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005296">
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        <obo:IAO_0000116>Chemical Nature: Small molecule, other
Receptor: TLR4
Mechanism of Action: None
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: Other
Point of Contact: Robert Ernst, University of Maryland - Baltimore</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Robert Ernst</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>BECC470b</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=32</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28487429</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=29861179</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33309485</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
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        <obo:VO_0005328>32</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>BECC470b vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005297 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005297">
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        <obo:IAO_0000116>Chemical Nature: (1) Synthetic derivative of natural compound, (2) other
Receptor: TLR4
Mechanism of Action: None
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: None
Point of Contact: Robert Ernst, University of Maryland-Baltimore</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Robert Ernst</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>BECC438s</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=33</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>33</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>BECC438s vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005298 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005298">
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        <obo:IAO_0000116>Chemical Nature: Small molecule, other
Receptor: TLR4
Mechanism of Action: None
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: None
Point of Contact: Robert Ernst, University of Maryland Baltimore</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Robert Ernst</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>BECC438b</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=31</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28487429</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=29861179</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33309485</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>31</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>BECC438b vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005299 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005299">
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        <obo:IAO_0000116>Chemical Nature: Combination adjuvant
Receptor: TLR4
Mechanism of Action: TLR4 and potentially inflammasome
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: None
Point of Contact: Darrick Carter, PAI Life Services</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Darrick Carter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>AlT4</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=19</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>19</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>AlT4 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005300 -->

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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005300</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Combination adjuvant
Receptor: TLR3
Mechanism of Action: TLR3 agonist plus potential inflammasome
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: None
Point of Contact: Darrick Carter, PAI Life Services</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Darrick Carter</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>AlT3</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=21</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005305"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>21</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>AlT3 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005301 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005301">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005272"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005306"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005301</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Receptor: (1) TLR7, (2) TLR8
Mechanism of Action: TLR7/8 dual agonist - lymph node delivery
Immune profile induced: Th1-biased
Other Features/Characteristics: Promotes antibody affinity maturation
Point of Contact: Sunil David, Virovax</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Sunil David</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Alhydroxiquim-II</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=12</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33521604</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33654090</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005272"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005306"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>12</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Alhydroxiquim-II vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005302 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005302">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005314"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005302</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: (1) Synthetic derivative of natural compound, (2) Emulsion, (3) Combination adjuvant, (4) Other
Receptor: TLR4
Mechanism of Action: Adjuplex enhances cross presentation to CD8 T cells and GLA stimulates TLR4 signaling
Immune profile induced: Mixed Th1/Th17
Other Features/Characteristics: None
Point of Contact: Marulasiddappa Suresh, UW Madison</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Marulasiddappa Suresh</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Adjuplex+GLA</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=15</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32984856</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33444400</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33767689</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005314"/>
        <obo:VO_0005328>15</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Adjuplex+GLA vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005303 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005303">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005303</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Receptor: Dendritic cells (unknown receptor)
Mechanism of Action: Innate immune activation/enhancer
Immune profile induced: Mixed Th1/Th2
Other Features/Characteristics: None
Point of Contact: Dennis Carson, UCSD</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Dennis Carson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>2F52</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=8</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=29751735</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>8</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>2F52 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005304 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005304">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005304</metadata:prefixIRI>
        <obo:IAO_0000115>A role of a material entity that binds to TLR4 and activates the receptor for pathogen recognition and activation of innate immunity.</obo:IAO_0000115>
        <obo:IAO_0000116>TLR4 agonist role</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Toll-like receptor 4 agonist role</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/TLR4</obo:IAO_0000119>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>TLR4 receptor role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005305 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005305">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005305</metadata:prefixIRI>
        <obo:IAO_0000115>A role of a material entity that binds to TLR3 and activates the receptor for pathogen recognition and activation of innate immunity.</obo:IAO_0000115>
        <obo:IAO_0000116>TLR3 agonist role</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Toll-like receptor 3 agonist role</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/TLR3</obo:IAO_0000119>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>TLR3 receptor role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005306 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005306">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005306</metadata:prefixIRI>
        <obo:IAO_0000115>A role of a material entity that binds to TLR8 and activates the receptor for pathogen recognition and activation of innate immunity.</obo:IAO_0000115>
        <obo:IAO_0000116>TLR8 agonist role</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Toll-like receptor 8 agonist role</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/TLR8</obo:IAO_0000119>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>TLR8 receptor role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005307 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005307">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005307</metadata:prefixIRI>
        <obo:IAO_0000115>A role of a material entity that binds to TLR2 and activates the receptor for pathogen recognition and activation of innate immunity.</obo:IAO_0000115>
        <obo:IAO_0000116>TLR2 agonist role</obo:IAO_0000116>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Toll-like receptor 2 agonist role</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/TLR2</obo:IAO_0000119>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>TLR2 receptor role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005308 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005308">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000144"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005308</metadata:prefixIRI>
        <obo:IAO_0000115>Process profile that reflects a pattern of a specific immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>immune response profile</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005309 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005309">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005309</metadata:prefixIRI>
        <obo:IAO_0000115>An immune profile that is characterized by the presence of Type 1 T helper (Th1) cells that produce interferon-gamma, interleukin (IL)-2, and tumor necrosis factor (TNF)-beta, which activate macrophages and are responsible for cell-mediated immunity and phagocyte-dependent protective responses.</obo:IAO_0000115>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/T_helper_cell</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/10579123/</obo:IAO_0000119>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>Th1-biased immune profile</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005310">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005310</metadata:prefixIRI>
        <obo:IAO_0000115>An immune profile that is characterized by the presence of T type 2 Th (Th2) cells that produce IL-4, IL-5, IL-10, and IL-13, which are responsible for strong antibody production, eosinophil activation, and inhibition of several macrophage functions, thus providing phagocyte-independent protective responses.</obo:IAO_0000115>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/T_helper_cell</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/10579123/</obo:IAO_0000119>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>Th2-biased immune profile</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005311 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005311">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005311</metadata:prefixIRI>
        <obo:IAO_0000115>An immune profile that is characterized by the presense of both Type 1 and Type 2 T helper  (Th1 and Th2) cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/T_helper_cell</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/10579123/</obo:IAO_0000119>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>Th1/Th2 mixed immune profile</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005313 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005313">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005313</metadata:prefixIRI>
        <obo:IAO_0000115>An immune profile that is characterized by the presence of T helper 17 cells (Th17), a subset of pro-inflammatory T helper cells defined by their production of interleukin 17 (IL-17). They are related to T regulatory cells and the signals that cause Th17 to differentiate and inhibit Treg differentiation.</obo:IAO_0000115>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/T_helper_17_cell</obo:IAO_0000119>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>Th17 immune profile</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005314 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005314">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005308"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005314</metadata:prefixIRI>
        <obo:IAO_0000115>An immune profile that is characterized by the presense of both Type 1 and Type 17 T helper  (Th1 and Th17) cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/T_helper_cell</obo:IAO_0000119>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>Th1/Th17 mixed immune profile</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005315 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005315">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005202"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005315</metadata:prefixIRI>
        <obo:IAO_0000115>A SARS-CoV-2 subunit vaccine by Clover Biopharmaceuticals AUS Pty Ltd that contains the S protein from the B.1.351 variant.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>SCB-2020S</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04950751</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5879</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/PR_P0DTC2"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5879</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SCB-2020S vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005316 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005316">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005269"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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    <!-- http://purl.obolibrary.org/obo/VO_0005317 -->

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        <obo:IAO_0000115>A SARS-CoV-2 subunit vaccine by Baiya Phytopharm Co., Ltd.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005318 -->

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        <obo:IAO_0000115>A SARS-CoV-2 recombinant vector vaccine manufactured by CyanVac LLC</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005319 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005320 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005321 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005322 -->

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        <obo:IAO_0000115>A SARS-CoV-2 DNA vaccine developed by AnGes, named as AG0302-COVID19.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>AG0302-COVID19</obo:IAO_0000118>
        <obo:IAO_0000119>NCT04993586</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5882</obo:IAO_0000119>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php</obo:IAO_0000119>
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        <obo:IAO_0000115>An Advax-CpG vaccine adjuvant that includes an inulin-based polysaccharide (Advax) and a CpG oligodeoxynucleotide CpG55.2.</obo:IAO_0000115>
        <obo:IAO_0000116>Pubmed References:Chemical Nature: (1) combination adjuvant
Mechanism of Action: (1) complement, (2) dendritic cells, (3) other/unknown, (4) TLR9 Immune profile induced: mixed Th1
Other Features/Characteristics: (1) induces CD8 T cells, (2) provides innate protection, (3) anti-inflammatory, (4) promotes antibody affinity maturation, (5) effective in newborns, (6) high stability
By routes: SQ, IM
Point of Contact: Nikolai Petrovsky, Vaxine LTD</obo:IAO_0000116>
        <obo:IAO_0000117>Nikolai Petrovsky</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Advax-CpG55.2</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=38</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/32636840/</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32849580</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33301675</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34069575</obo:IAO_0000119>
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        <obo:VO_0005328>38</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Advax-CpG55.2 vaccine adjuvant</rdfs:label>
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        <obo:IAO_0000115>A vaccine adjuvant that is synthesized by derivatizing a natural Momordica saponin in one step.  VSA-2 is chemically stable. VSA-2 is much less toxic than QS-21.  VSA-2 is more Th1-biased than QS-21. Momordica saponins are isolated from widely available and sustainable sources.</obo:IAO_0000115>
        <obo:IAO_0000116>Pubmed References:
Chemical Nature: (1) Synthetic derivative of natural compound
Mechanism of Action: unknown
Immune profile induced: mixed Th1/Th2
Other Features/Characteristics: (1) synthetic saponin with lower toxicity and higher stability than QS21
By routes: SQ
Point of Contact: Pengfei Wang, University of Alabama
https://www.ncbi.nlm.nih.gov/pubmed/?term=32101001</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Pengfei Wang</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>VSA-2</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=42</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32101001</obo:IAO_0000119>
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        <rdfs:label>VSA-2 vaccine adjuvant</rdfs:label>
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        <obo:IAO_0000115>A vaccine adjuvant that is prepared by derivatizing a natural Momordica saponin in one chemical step. VSA-1 is chemically more stable than QS-21. VSA-1 is much less toxic than QS-21. The Momordica saponins are from sustainable sources and widely available.</obo:IAO_0000115>
        <obo:IAO_0000116>Pubmed References:
Chemical Nature: (1) Synthetic derivative of natural compound
Mechanism of Action: unknown
Immune profile induced: mixed Th1/Th2
Other Features/Characteristics: (1) synthetic saponin with lower toxicity and higher stability than QS21
By routes: SQ
Point of Contact: Pengfei Wang, University of Alabama
https://www.ncbi.nlm.nih.gov/pubmed/?term=31657920</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Pengfei Wang</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>VSA-1</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=41</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=31657920</obo:IAO_0000119>
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        <obo:VO_0005328>41</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>VSA-1 vaccine adjuvant</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005327 -->

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        <obo:IAO_0000115>A vaccine adjuvant that is a potent adjuvant for antibody and cellular responses to protein, polypeptide and small peptide antigens. rOv-ASP-1 stands for Recombinant Onchocerca volvulus activation-associated secreted protein-1.</obo:IAO_0000115>
        <obo:IAO_0000116>Pubmed References:
Chemical Nature: (1) Protein
Mechanism of Action: unknown
Immune profile induced: Th1
Other Features/Characteristics: (1) Induces CD8 T cells, (2) provides innate protection, (3) promotes antibody affinity maturation.
By routes: IM
Point of Contact: Sara Lustigman, New York Blood Center</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Sara Lustigman</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Recombinant O. volvulus activation-associated secreted protein-1</obo:IAO_0000118>
        <obo:IAO_0000118>rOv-ASP-1</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=43</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=1583768</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=18341617</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=18675867</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=22615877</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24681229</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=25736195</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26795365</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=29764680</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32471056</obo:IAO_0000119>
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        <obo:VO_0005328>43</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>rOv-ASP-1 vaccine adjuvant</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005329 -->

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        <obo:IAO_0000115>A vaccine adjuvant that includes double mutant of heat-labile E. coli toxin (LT) at R192G/L211A or LT(R192G/L211A)</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: protein
Mechanism of Action: CGM1 ganglioside, cAMP, inflammasome
Immune profile induced: mixed Th1/Th17
Other Features/Characteristics: Induces mucosal immunity (IM, ID, SQ, SL, oral, , transcutaneous), Induces epitope spreading, Promotes antibody affinity maturation, Effective in newborns, promotes antibody epitope spreading
By routes: IM, ID, SL, oral, SQ, IN, IP, intragastric, transcutaneous, transdermal, buccal, intrarectal
Point of Contact: Elizabeth Norton, Tulane University

https://www.ncbi.nlm.nih.gov/pubmed/?term=21288994
https://www.ncbi.nlm.nih.gov/pubmed/?term=6803349
https://www.ncbi.nlm.nih.gov/pubmed/?term=26540197
https://www.ncbi.nlm.nih.gov/pubmed/?term=4927082
https://www.ncbi.nlm.nih.gov/pubmed/?term=26305793
https://www.ncbi.nlm.nih.gov/pubmed/?term=25111827
https://www.ncbi.nlm.nih.gov/pubmed/?term=24453241
https://www.ncbi.nlm.nih.gov/pubmed/?term=22202122
https://www.ncbi.nlm.nih.gov/pubmed/?term=25803825
https://www.ncbi.nlm.nih.gov/pubmed/?term=23541621
https://www.ncbi.nlm.nih.gov/pubmed/?term=26018536
https://www.ncbi.nlm.nih.gov/pubmed/?term=5461379
https://www.ncbi.nlm.nih.gov/pubmed/?term=3578125
https://www.ncbi.nlm.nih.gov/pubmed/?term=5216441
https://www.ncbi.nlm.nih.gov/pubmed/?term=19897067
https://www.ncbi.nlm.nih.gov/pubmed/?term=25944298
https://www.ncbi.nlm.nih.gov/pubmed/?term=6424635
https://www.ncbi.nlm.nih.gov/pubmed/?term=3916310
https://www.ncbi.nlm.nih.gov/pubmed/?term=4826740
https://www.ncbi.nlm.nih.gov/pubmed/?term=2884428
https://www.ncbi.nlm.nih.gov/pubmed/?term=30778066
https://www.ncbi.nlm.nih.gov/pubmed/?term=4893257
https://www.ncbi.nlm.nih.gov/pubmed/?term=28063704
https://www.ncbi.nlm.nih.gov/pubmed/?term=4375349
https://www.ncbi.nlm.nih.gov/pubmed/?term=28792004
https://www.ncbi.nlm.nih.gov/pubmed/?term=25765967
https://www.ncbi.nlm.nih.gov/pubmed/?term=25483682
https://www.ncbi.nlm.nih.gov/pubmed/?term=30638799
https://www.ncbi.nlm.nih.gov/pubmed/?term=21326197
https://www.ncbi.nlm.nih.gov/pubmed/?term=31757774
https://www.ncbi.nlm.nih.gov/pubmed/?term=31427449
https://www.ncbi.nlm.nih.gov/pubmed/?term=6957164
https://www.ncbi.nlm.nih.gov/pubmed/?term=33465933
https://www.ncbi.nlm.nih.gov/pubmed/?term=33465933
https://www.ncbi.nlm.nih.gov/pubmed/?term=33465933
https://www.ncbi.nlm.nih.gov/pubmed/?term=31641151
https://www.ncbi.nlm.nih.gov/pubmed/?term=27133878
https://www.ncbi.nlm.nih.gov/pubmed/?term=27676456
https://www.ncbi.nlm.nih.gov/pubmed/?term=27226279
https://www.ncbi.nlm.nih.gov/pubmed/?term=22406456
https://www.ncbi.nlm.nih.gov/pubmed/?term=30787109
https://www.ncbi.nlm.nih.gov/pubmed/?term=24403527
https://www.ncbi.nlm.nih.gov/pubmed/?term=24403527
https://www.ncbi.nlm.nih.gov/pubmed/?term=30563789
https://www.ncbi.nlm.nih.gov/pubmed/?term=31757774
https://www.ncbi.nlm.nih.gov/pubmed/?term=30473185
https://www.ncbi.nlm.nih.gov/pubmed/?term=30248001
https://www.ncbi.nlm.nih.gov/pubmed/?term=24049109
https://www.ncbi.nlm.nih.gov/pubmed/?term=30797634
https://www.ncbi.nlm.nih.gov/pubmed/?term=31482013
https://www.ncbi.nlm.nih.gov/pubmed/?term=29771685
https://www.ncbi.nlm.nih.gov/pubmed/?term=31757774
https://www.ncbi.nlm.nih.gov/pubmed/?term=25444830

Clinical trials:
https://clinicaltrials.gov/ct2/show/NCT03922061
https://clinicaltrials.gov/ct2/show/NCT04232943
https://clinicaltrials.gov/ct2/show/NCT02531685
https://clinicaltrials.gov/ct2/show/NCT02052934
https://clinicaltrials.gov/ct2/show/NCT02531802
https://clinicaltrials.gov/ct2/show/NCT01147445
https://clinicaltrials.gov/ct2/show/NCT03548064
https://clinicaltrials.gov/ct2/show/ NCT01739231
https://clinicaltrials.gov/ct2/show/NCT03404674
https://clinicaltrials.gov/ct2/show/NCT03729219
https://clinicaltrials.gov/ct2/show/NCT04826094</obo:IAO_0000116>
        <obo:IAO_0000117>Elizabeth Norton</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>dmLT</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=13</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=19897067</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=21288994</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=22202122</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=23541621</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24453241</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=25111827</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=25803825</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26018536</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26305793</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26540197</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=3578125</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=4927082</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=5216441</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=5461379</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=6803349</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005314"/>
        <obo:VO_0005328>13</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>dmLT vaccine adjuvant</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005330 -->

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        <obo:IAO_0000116>Chemical Nature: (1) other (Peptide)
Mechanism of Action: C5aR1 on mononuclear phagocytes
Immune profile induced: mixed Th1/Th2
Other Features/Characteristics: (1) Induces CD8 T cells, (2) provides innate protection, (3) promotes antibody affinity maturation.
By routes: SQ, IP, IV.
Point of Contact: Joseph Vetro, University of Nebraska Medical Center
https://pubmed.ncbi.nlm.nih.gov/9013982/, https://pubmed.ncbi.nlm.nih.gov/9013982/, https://pubmed.ncbi.nlm.nih.gov/10516626/, https://pubmed.ncbi.nlm.nih.gov/10799917/, https://pubmed.ncbi.nlm.nih.gov/10799917/, https://pubmed.ncbi.nlm.nih.gov/12538044/, https://pubmed.ncbi.nlm.nih.gov/19428909/, https://pubmed.ncbi.nlm.nih.gov/21723901/</obo:IAO_0000116>
        <obo:IAO_0000117>Joseph Vetro</obo:IAO_0000117>
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        <obo:IAO_0000115>A SARS-CoV-2 RNA vaccine manufactured by VLP Therapeutics Japan, LLC</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>VLPCOV-01</obo:IAO_0000118>
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        <obo:IAO_0000115>A vaccine adjuvant that includes UM-3004, a small molecule TLR7/8 agonist that can stimulate Th1-biased immune profile.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: (1) small molecule
Mechanism of Action: TLR7/8 agonist
Immune profile induced: Th1-biased
Route of immunization: IM
Point of Contact: Helene Bazin-Lee, University of Montana</obo:IAO_0000116>
        <obo:IAO_0000117>Ani M. Bernardi</obo:IAO_0000117>
        <obo:IAO_0000117>Helene Bazin-Lee</obo:IAO_0000117>
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        <obo:IAO_0000115>A vaccine adjuvant that includes UM-3003, a small molecule TLR7/8 agonist that can stimulate Th1-biased immune profile.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: (1) small molecule
Mechanism of Action: TLR7/8 agonist
Immune profile induced: Th1-biased
Route of immunization: IM
Point of Contact: Helene Bazin-Lee, University of Montana</obo:IAO_0000116>
        <obo:IAO_0000117>Ani M. Bernardi</obo:IAO_0000117>
        <obo:IAO_0000117>Helene Bazin-Lee</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/32210973</obo:IAO_0000119>
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        <obo:VO_0005328>45</obo:VO_0005328>
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        <obo:IAO_0000115>A vaccine adjuvant made from the A subunit of heat-labile (LT) enterotoxin of Enterotoxigenic Escherichia coli (ETEC). This LTA1 adjuvant is able to induce Th1, Th2, and Th17 immune responses.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: (1) Protein
Mechanism of Action: cAMP, inflammasome induction
Immune profile induced: mixed Th1/Th2/Th17
Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces epitope spreading, (3) Promotes antibody affinity maturation, (4) Promotes antibody epitope spreading, (5) High stability
Route of immunization: IM, IN, SL, ID, IP
Point of Contact: Elizabeth Norton, Tulane University</obo:IAO_0000116>
        <obo:IAO_0000117>Ani M. Bernardi</obo:IAO_0000117>
        <obo:IAO_0000117>Elizabeth Norton</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>LTA1</obo:IAO_0000118>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/22526674</obo:IAO_0000119>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/6957164</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0005356 -->

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        <obo:IAO_0000115>A carbohydrate vaccine adjuvant that is a glucan carbohydrate microcapsules with a beta(1-3)/beta(1-6) - linked glucan structure to allow targeting of antigens to macrophages or neutrophils through interactions with the beta-glucan receptor found uniquely on the surface of these cell types. Adjuvax- ligand complexes are formed by physically entrapping or crosslinking the ligand within the beta-glucan.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>DOI: 10.1021</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0005357 -->

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        <obo:IAO_0000115>A vaccine adjuvant that includes an inulin-based polysaccharide (Advax) and a CpG oligodeoxynucleotide (ODN).</obo:IAO_0000115>
        <obo:IAO_0000116>Pubmed References:Chemical Nature: (1) combination adjuvant
Mechanism of Action: (1) complement, (2) dendritic cells, (3) other/unknown, (4) TLR9 Immune profile induced: mixed Th1
Other Features/Characteristics: (1) induces CD8 T cells, (2) provides innate protection, (3) anti-inflammatory, (4) promotes antibody affinity maturation, (5) effective in newborns, (6) high stability
By routes: SQ, IM
Point of Contact: Nikolai Petrovsky, Vaxine LTD</obo:IAO_0000116>
        <obo:IAO_0000117>Nikolai Petrovsky</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
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        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Advax-CpG vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005358 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005358</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant includes 3-O-desacyl-4&apos;-monophosphoryl lipid A (MPL) from Salmonella minnesota and a saponin molecule (QS-21) purified from plant extract Quillaja saponaria Molina, combined in a liposomal formulation consisting of dioleoyl phosphatidylcholine (DOPC) and cholesterol in phosphate-buffered saline solution.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.fda.gov/media/107538/download#:~:text=The%20AS01B%20adjuvant%20suspension%20is,DOPC)%20and%20cholesterol%20in%20phosphate%2D</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>AS01B vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005359">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005359</metadata:prefixIRI>
        <obo:IAO_0000115>An AS02 vaccine adjuvant contains 50 ug MPL and 50ug QS21, 250uL of SB62 (oil/water emulsion) in phosphate buffered saline (PBS) per volume of 0.5 mL.</obo:IAO_0000115>
        <obo:IAO_0000118>As02a</obo:IAO_0000118>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT00308061</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>AS02A vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005360 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005360</metadata:prefixIRI>
        <obo:IAO_0000115>A carbohydrate vaccine adjuvant that is aminoglycan consisting of beta-(1-&gt;4)-linked D-glucosamine residues.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>CHEBI:16261</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:24346613</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>chitosan vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005361 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005361">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001271"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005361</metadata:prefixIRI>
        <obo:IAO_0000115>A Montanide vaccine adjuvant that is a water-dispersed liquid IMS 1313 nanoparticle combined with an immuno-stimulating compound.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>IMS 1313 N VGPR</obo:IAO_0000118>
        <obo:IAO_0000118>IMS-1313</obo:IAO_0000118>
        <obo:IAO_0000119>https://scialert.net/abstract/?doi=ijps.2018.167.174</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Montanide IMS 1313 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005362 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001271"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005362</metadata:prefixIRI>
        <obo:IAO_0000115>A water-dispersed liquid nanoparticle combined with an immuno-stimulating compound.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>ISA-206</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:8961504</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Montanide ISA 206 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005363 -->

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        <obo:IAO_0000115>A Montanide vaccine adjuvant that Mannide oleate derivative in a mineral oil solution ( Seppic SA, France).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>ISA-50</obo:IAO_0000118>
        <obo:IAO_0000119>http://vetarhiv.vef.unizg.hr/papers/74-2/raman.pdf</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Montanide ISA 50 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005364 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005364">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005364</metadata:prefixIRI>
        <obo:IAO_0000115>A carbohydrate vaccine adjuvant that is tomatidine in which the hydroxy group at position 3 is linked to lycotetraose, a tetrasaccharide composed of two units of D-glucose, one unit of D-xylose, and one unit of D-galactose.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>CHEBI:9630</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Tomatine vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005365 -->

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        <obo:IAO_0000115>A carbohydrate vaccine adjuvant that polysaccharide prepared from the cell wall of Saccaromyces cerevisiae (bakers&apos; yeast).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:11380697</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Zymosan vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005366 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005366</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant that is oil-based adjuvant (Adjuvant XtendIII®; Grand Laboratories, Larchwood, IA).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>XtendIII vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005367 -->

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        <obo:IAO_0000115>A microbial derivative vaccine adjuvant that is monophosphoryl lipid A (detoxified endotoxin) from S. minnesota (MPL) and synthetic trehalose dicorynomycolate (TDM) in 2% oil (squalene)-Tween 80-water.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>Monophosphoryl-lipid A + Trehalose dicorynomycolate</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.sigmaaldrich.com/US/en/product/sigma/m6536</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>MPL + TDM vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005368 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000187"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005368</metadata:prefixIRI>
        <obo:IAO_0000115>A muramyl dipeptide vaccine adjuvant that muramyl dipeptide derivative (threonyl-MDP) in an oil-in-water (o/w) emulsion vehicle.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>SAF</obo:IAO_0000118>
        <obo:IAO_0000119>https://link.springer.com/protocol/10.1385/1-59259-083-7:229</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Syntex Adjuvant Formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005369 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005369</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant that diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>DBP</obo:IAO_0000118>
        <obo:IAO_0000119>CHEBI:34687</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26319029</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>dibutyl phthalate vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005370 -->

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        <obo:IAO_0000115>A vaccine adjuvant that includes naturally occurring trivalent alcohol.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>glycerine, 1, 2, 3-propanetriol</obo:IAO_0000118>
        <obo:IAO_0000119>https://academic.oup.com/cid/article/45/10/1277/277413</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005313"/>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>glycerol vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005371 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005371</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant includes three palmitic acid groups that are bound in an ester and amide linkage to a cysteine residue.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>Tripalmitoyl-S-glyceryl-cysteine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:24130558</obo:IAO_0000119>
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        <rdfs:label>Pam3Cys vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005372 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005372</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant that is equimolar mixture of the cationic lipid GAP-DMORIE [(±)-N-(3-aminopropyl)-N,N-dimethyl-2,3-bis(cis-9-tetradecenyloxy)-1-propanaminium bromide)] and a neutral colipid DPyPE (1,2-diphytanoyl-sn-glydero-3-phosphoethanolamine).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:21118032</obo:IAO_0000119>
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        <rdfs:label>Vaxfectin vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005373 -->

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        <obo:IAO_0000115>A vaccination process that involves adding a vaccine into a host prior to disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000118>preventive vaccination</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Preventive_healthcare</obo:IAO_0000119>
        <obo:IAO_0000119>preventative vaccination</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>prophylactic vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005374 -->

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        <obo:IAO_0000115>A vaccination process that involves adding a vaccine into a host after a disease has occurred.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Therapeutic_vaccines</obo:IAO_0000119>
        <oboInOwl:inSubset>vaccination</oboInOwl:inSubset>
        <rdfs:label>therapeutic vaccination</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005375 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005375</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuant that is derived from Salmonella enterica serovar typhimurium and is able to induce Th1/Th2/Th17 immune responses through the mechanism of action of TLR4, inflammasome, and DC activation.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: other
Mechanism of Action: TLR4; inflammasome; DC activation
Immune profile induced: Th1/Th2/Th17
Receptor: TLR4, NLRP3
Storage information: -20 or -80C
Point of Contact: Lisa Morici, Tulane University</obo:IAO_0000116>
        <obo:IAO_0000117>Lisa Morici</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>T-vant</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=61</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33498352</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34069796</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005378"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005376"/>
        <obo:VO_0005328>61</obo:VO_0005328>
        <obo:VO_0005377 rdf:resource="http://purl.obolibrary.org/obo/PR_000001155"/>
        <obo:VO_0005377 rdf:resource="http://purl.obolibrary.org/obo/PR_000011271"/>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>T-vant vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005376 -->

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        <obo:IAO_0000115>An immune profile that is characterized by the presense of Type 1 Type 2, and Th17 T helper cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/T_helper_cell</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/10579123/</obo:IAO_0000119>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>Th1/Th2/Th17 mixed immune profile</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005378 -->

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        <obo:IAO_0000115>A role of a material entity that binds to NLRP3.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/NLRP3</obo:IAO_0000119>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>NLRP3 receptor role</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005379 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005379</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: Nucleic Acid
Mechanism of Action: TLR/RLR-agonist
Immune profile induced: Th1/Th2

Route of immunization: IM and IN
Point of Contact: Xiaoliang Ren, Yisheng Bio

Ongoing clinical trial:
https://clinicaltrials.gov/ct2/show/NCT02657161
https://clinicaltrials.gov/ct2/show/NCT02956421</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000117>Xiaoliang Ren</obo:IAO_0000117>
        <obo:IAO_0000118>PIKA</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=55</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=17484805</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=20538850</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=21468931</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26765968</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28118938</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=29174316</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34766005</obo:IAO_0000119>
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        <obo:VO_0005328>55</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>PIKA vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005380 -->

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        <obo:IAO_0000116>Chemical Nature: peptide
Mechanism of Action: activation of mast cells, epithelial cells, macrophages and dendritic cells
Immune profile induced: Th2-biased

Route of immunization: IM and IN
Point of Contact: Herman Staats, Duke University</obo:IAO_0000116>
        <obo:IAO_0000117>Herman Staats</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Mastoparan 7</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=53</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=31068425</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32047657</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34566991</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005310"/>
        <obo:VO_0005328>53</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Mastoparan 7 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005381 -->

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        <obo:IAO_0000116>Chemical Nature: small molecule
Mechanism of Action: mast cell activation
Immune profile induced: Th2-biased

Route of immunization: IN
Point of Contact: Herman Staats, Duke University</obo:IAO_0000116>
        <obo:IAO_0000117>Herman Staats</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Mast cell activator small molecules</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=54</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34566991</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005310"/>
        <obo:VO_0005328>54</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Mast cell activator small molecules vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005382 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005382">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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        <obo:IAO_0000116>Chemical Nature: small molecule
Mechanism of Action: Innate Immune Activation
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Ofer Levy, Precision Vaccines Program at Boston Children&apos;s Hospital</obo:IAO_0000116>
        <obo:IAO_0000117>Ofer Levy</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Precision Vaccines Program (PVP)-037</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=56</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>56</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Precision Vaccines Program (PVP)-037 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005383 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005383">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005383</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: small molecule
Mechanism of Action: TLR4 agonist
Immune profile induced: Th1/Th2

Route of immunization: IM and IN
Point of Contact: Robert Ernst, University of Maryland - Baltimore</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Robert Ernst</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>BECC470s</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=60</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>60</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>BECC470s vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005384 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005384">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005384</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: small molecule
Mechanism of Action: innate immune activation
Immune profile induced: Th1-biased
Route of immunization: IM
Point of Contact: Helene Bazin-Lee, University of Montana</obo:IAO_0000116>
        <obo:IAO_0000117>Helene Bazin-Lee</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>TRAC478</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=48</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>48</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>TRAC478 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005385">
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        <obo:IAO_0000116>Chemical Nature: small molecule
Mechanism of Action: innate immune activation
Immune profile induced: Th1/Th17

Route of immunization: IM and IN
Point of Contact: Christopher Fox, AAHI</obo:IAO_0000116>
        <obo:IAO_0000117>Christopher Fox</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>GLA-3M-052-LS</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=58</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34248966</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34795290</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005314"/>
        <obo:VO_0005328>58</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>GLA-3M-052-LS vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005386">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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        <obo:IAO_0000116>Chemical Nature: small molecule
Mechanism of Action: innate immune activation
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Christopher Fox, AAHI</obo:IAO_0000116>
        <obo:IAO_0000117>Christopher Fox</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>3M-052-SE</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=57</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28429728</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=30089691</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32213623</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34131024</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34972105</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=35572573</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>57</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>3M-052-SE vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005387 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005387">
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        <obo:IAO_0000116>Chemical Nature: small molecule
Mechanism of Action: innate immune activation
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Christopher Fox, AAHI

Clinical trials:
https://clinicaltrials.gov/ct2/show/NCT04177355
https://clinicaltrials.gov/ct2/show/NCT04915768
https://clinicaltrials.gov/ct2/show/NCT05197712</obo:IAO_0000116>
        <obo:IAO_0000117>Christopher Fox</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>3M-052-Alum</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=59</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=27847326</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32561559</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33971664</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34117252</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34266981</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>59</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>3M-052-Alum vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005388 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005388">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
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        <obo:IAO_0000116>Chemical Nature: (1) emulsion
Mechanism of Action: unknown
Immune profile induced: Th1/Th17

Route of immunization: IM
Point of Contact: Patrice Dubois, Vaccine Formulation Institute

Clinical trial:
https://clinicaltrials.gov/ct2/show/NCT04702178</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Patrice Dubois</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>SWE</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=50</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=30849373</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32411401</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005314"/>
        <obo:VO_0005328>50</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>SWE vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005389 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005389">
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        <obo:IAO_0000116>Chemical Nature: (1) Emulsion (with Saponin)
Mechanism of Action: unknown
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Patrice Dubois, Vaccine Formulation Institute</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Patrice Dubois</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>SQ</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=52</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33688647</obo:IAO_0000119>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>52</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>SQ vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005390 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005390">
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        <obo:IAO_0000116>Chemical Nature: (1) other (liposome with Saponin)
Mechanism of Action: unknown
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Patrice Dubois, Vaccine Formulation Institute</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Patrice Dubois</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>LQ</obo:IAO_0000118>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32156809</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0005394 -->

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        <obo:IAO_0000115>A SARS-CoV-2 RNA vaccine by Gritstone Bio, Inc.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005398 -->

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        <obo:IAO_0000115>A SARS-CoV-2 RNA vaccine by the University of Melbourne.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>MIPSCo-mRNA-RBD-1 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005399 -->

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        <obo:IAO_0000115>A SARS-CoV-2 inactivated vaccine developed by Osve Pharmaceutical Company.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Osvid-19 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005400 -->

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        <obo:IAO_0000115>A SARS-CoV-2 protein subunit vaccine manufactured by Speransa Therapeutics.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Prime-2-CoV-Beta vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005401 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RH109 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005402 -->

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        <rdfs:label>RQ3013 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005403 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005411 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005412 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005413 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005414 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005415 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005416 -->

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        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118>mRNA-1273.529</obo:IAO_0000118>
        <obo:IAO_0000119>NCT05249829</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5926</obo:IAO_0000119>
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        <obo:IAO_0000115>A SARS-CoV-2 inactivated vaccine developed by China National Biotec Group Company Limited</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>NCT05374954</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5940</obo:IAO_0000119>
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        <obo:VO_0001818>5940</obo:VO_0001818>
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        <rdfs:label>Omicron COVID-19 inactivated vaccine by China National Biotec Group Company Limited</rdfs:label>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php</obo:IAO_0000119>
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        <rdfs:label>authorized COVID-19 virus-like particle vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005419 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005419</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: other
Mechanism of Action: Activation of APCs, activation of T cells and stimulating B cell proliferation (IgG)
Immune profile induced: Th1-biased

Route of immunization: IM and SQ
Point of Contact: Matthew Heath, Allergy Therapeutics (UK) Ltd</obo:IAO_0000116>
        <obo:IAO_0000117>Ani Bernardi</obo:IAO_0000117>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Matthew Heath</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>MCT</obo:IAO_0000118>
        <obo:IAO_0000118>MCT vaccine adjuvant</obo:IAO_0000118>
        <obo:IAO_0000118>MicroCrystalline Tyrosine</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=25</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28347293</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28468322</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=28953265</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=29592962</obo:IAO_0000119>
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        <obo:VO_0005328>25</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>MicroCrystalline Tyrosine vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005420 -->

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        <obo:IAO_0000116>Chemical Nature: other
Mechanism of Action: TLR4; Innate Immune Activation
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Christopher Fox, AAHI

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=27142329
https://www.ncbi.nlm.nih.gov/pubmed/?term=21060869
https://www.ncbi.nlm.nih.gov/pubmed/?term=20944089
https://www.ncbi.nlm.nih.gov/pubmed/?term=20944089
https://www.ncbi.nlm.nih.gov/pubmed/?term=20944089
https://www.ncbi.nlm.nih.gov/pubmed/?term=21816196
https://www.ncbi.nlm.nih.gov/pubmed/?term=21690242
https://www.ncbi.nlm.nih.gov/pubmed/?term=21060869
https://www.ncbi.nlm.nih.gov/pubmed/?term=22291184
https://www.ncbi.nlm.nih.gov/pubmed/?term=22291184
https://www.ncbi.nlm.nih.gov/pubmed/?term=23045649
https://www.ncbi.nlm.nih.gov/pubmed/?term=23045649
https://www.ncbi.nlm.nih.gov/pubmed/?term=22509423
https://www.ncbi.nlm.nih.gov/pubmed/?term=22896687
https://www.ncbi.nlm.nih.gov/pubmed/?term=23904160
https://www.ncbi.nlm.nih.gov/pubmed/?term=23954378
https://www.ncbi.nlm.nih.gov/pubmed/?term=22425788
https://www.ncbi.nlm.nih.gov/pubmed/?term=22891286
https://www.ncbi.nlm.nih.gov/pubmed/?term=22891286
https://www.ncbi.nlm.nih.gov/pubmed/?term=23624057
https://www.ncbi.nlm.nih.gov/pubmed/?term=23624057
https://www.ncbi.nlm.nih.gov/pubmed/?term=23228811
https://www.ncbi.nlm.nih.gov/pubmed/?term=25024362
https://www.ncbi.nlm.nih.gov/pubmed/?term=25030053
https://www.ncbi.nlm.nih.gov/pubmed/?term=24404140
https://www.ncbi.nlm.nih.gov/pubmed/?term=24556505
https://www.ncbi.nlm.nih.gov/pubmed/?term=24556505
https://www.ncbi.nlm.nih.gov/pubmed/?term=24397898
https://www.ncbi.nlm.nih.gov/pubmed/?term=24397898
https://www.ncbi.nlm.nih.gov/pubmed/?term=24728521
https://www.ncbi.nlm.nih.gov/pubmed/?term=24728521
https://www.ncbi.nlm.nih.gov/pubmed/?term=25367751
https://www.ncbi.nlm.nih.gov/pubmed/?term=26541135
https://www.ncbi.nlm.nih.gov/pubmed/?term=25637347
https://www.ncbi.nlm.nih.gov/pubmed/?term=27005808
https://www.ncbi.nlm.nih.gov/pubmed/?term=26656121
https://www.ncbi.nlm.nih.gov/pubmed/?term=26874325
https://www.ncbi.nlm.nih.gov/pubmed/?term=26791076
https://www.ncbi.nlm.nih.gov/pubmed/?term=27466350
https://www.ncbi.nlm.nih.gov/pubmed/?term=27699241
https://www.ncbi.nlm.nih.gov/pubmed/?term=29176865
https://www.ncbi.nlm.nih.gov/pubmed/?term=27958370
https://www.ncbi.nlm.nih.gov/pubmed/?term=29263879
https://www.ncbi.nlm.nih.gov/pubmed/?term=29795025
https://www.ncbi.nlm.nih.gov/pubmed/?term=29983563
https://www.ncbi.nlm.nih.gov/pubmed/?term=29619252
https://www.ncbi.nlm.nih.gov/pubmed/?term=29619252
https://www.ncbi.nlm.nih.gov/pubmed/?term=27895131
https://www.ncbi.nlm.nih.gov/pubmed/?term=32636844
https://www.ncbi.nlm.nih.gov/pubmed/?term=29541075
https://www.ncbi.nlm.nih.gov/pubmed/?term=33705411
https://www.ncbi.nlm.nih.gov/pubmed/?term=35126135
https://www.ncbi.nlm.nih.gov/pubmed/?term=19679214
https://www.ncbi.nlm.nih.gov/pubmed/?term=26731269
https://www.ncbi.nlm.nih.gov/pubmed/?term=26453448
https://www.ncbi.nlm.nih.gov/pubmed/?term=26453448
https://www.ncbi.nlm.nih.gov/pubmed/?term=27456709
https://www.ncbi.nlm.nih.gov/pubmed/?term=32023469
https://www.ncbi.nlm.nih.gov/pubmed/?term=32402293
https://www.ncbi.nlm.nih.gov/pubmed/?term=32348377
https://www.ncbi.nlm.nih.gov/pubmed/?term=32697993
https://www.ncbi.nlm.nih.gov/pubmed/?term=29515589
https://www.ncbi.nlm.nih.gov/pubmed/?term=33046728
https://www.ncbi.nlm.nih.gov/pubmed/?term=31690678
https://www.ncbi.nlm.nih.gov/pubmed/?term=31174937
https://www.ncbi.nlm.nih.gov/pubmed/?term=30567978
https://www.ncbi.nlm.nih.gov/pubmed/?term=31362695
https://www.ncbi.nlm.nih.gov/pubmed/?term=29769270
https://www.ncbi.nlm.nih.gov/pubmed/?term=31521953
https://www.ncbi.nlm.nih.gov/pubmed/?term=28298421

Ongoing clinical trial:
https://clinicaltrials.gov/ct2/show/NCT01484548
https://clinicaltrials.gov/ct2/show/NCT01751048
https://clinicaltrials.gov/ct2/show/NCT02071758
https://clinicaltrials.gov/ct2/show/NCT02465216
https://clinicaltrials.gov/ct2/show/NCT01927159
https://clinicaltrials.gov/ct2/show/NCT01599897
https://clinicaltrials.gov/ct2/show/NCT01154049
https://clinicaltrials.gov/ct2/show/NCT03302897
https://clinicaltrials.gov/ct2/show/NCT02465216
https://clinicaltrials.gov/ct2/show/NCT02508376
https://clinicaltrials.gov/ct2/show/NCT03806686
https://clinicaltrials.gov/ct2/show/NCT01949909
https://clinicaltrials.gov/ct2/show/NCT01540474
https://clinicaltrials.gov/ct2/show/NCT02014727
https://clinicaltrials.gov/ct2/show/NCT02647489
https://clinicaltrials.gov/ct2/show/NCT02658253
https://clinicaltrials.gov/ct2/show/NCT01991561
https://clinicaltrials.gov/ct2/show/NCT01596725
https://clinicaltrials.gov/ct2/show/NCT01147068
https://clinicaltrials.gov/ct2/show/NCT03820414
https://clinicaltrials.gov/ct2/show/NCT03220724
https://clinicaltrials.gov/ct2/show/NCT03409276
https://clinicaltrials.gov/ct2/show/NCT01864876
https://clinicaltrials.gov/ct2/show/NCT02115815
https://clinicaltrials.gov/ct2/show/NCT01397604</obo:IAO_0000116>
        <obo:IAO_0000117>Ani Bernardi</obo:IAO_0000117>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Christopher Fox</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>GLA-SE</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=62</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT01484548</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT01751048</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT02071758</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=20944089</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=21060869</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=27142329</obo:IAO_0000119>
        <obo:VO_0005328>62</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>GLA-SE vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005421 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005421</metadata:prefixIRI>
        <obo:IAO_0000116>Chemical Nature: other
Mechanism of Action: TLR4; Innate Immune Activation
Immune profile induced: Mixed Th1/Th2

Route of immunization: IM
Point of Contact: Christopher Fox, AAHI

Ongoing clinical trial:
https://clinicaltrials.gov/ct2/show/NCT02508376
https://clinicaltrials.gov/ct2/show/NCT02647489
https://clinicaltrials.gov/ct2/show/NCT04177355
https://clinicaltrials.gov/ct2/show/NCT03589794</obo:IAO_0000116>
        <obo:IAO_0000117>Ani Bernardi</obo:IAO_0000117>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Christopher Fox</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>GLA-SLQ</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=63</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=22896687</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24465426</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24551202</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24556505</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26541135</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26862758</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=31174937</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=31690678</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32636844</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0005304"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>63</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>GLA-SLQ vaccine adjuvant</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005422 -->

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        <obo:IAO_0000116>Chemical Nature: other
Mechanism of Action: TLR4; Innate Immune Activation
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Christopher Fox, AAHI</obo:IAO_0000116>
        <obo:IAO_0000117>Ani Bernardi</obo:IAO_0000117>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Christopher Fox</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=30302281</obo:IAO_0000119>
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    <!-- http://purl.obolibrary.org/obo/VO_0005423 -->

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        <obo:IAO_0000116>Chemical Nature: other
Mechanism of Action: TLR4; Innate Immune Activation
Immune profile induced: n/a

Route of immunization: IM
Point of Contact: Christopher Fox, AAHI

Ongoing clinical trial:
https://clinicaltrials.gov/ct2/show/NCT03820414
https://clinicaltrials.gov/ct2/show/NCT02071758</obo:IAO_0000116>
        <obo:IAO_0000117>Ani Bernardi</obo:IAO_0000117>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=30386348</obo:IAO_0000119>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=35459225</obo:IAO_0000119>
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        <obo:VO_0005328>65</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>SLA-SE vaccine adjuvant</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005424 -->

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        <obo:IAO_0000116>Chemical Nature: other
Mechanism of Action: TLR4; Innate Immune Activation
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Christopher Fox, AAHI

Ongoing clinical trial:
https://clinicaltrials.gov/ct2/show/NCT02508376
https://clinicaltrials.gov/ct2/show/NCT02647489
https://clinicaltrials.gov/ct2/show/NCT04177355
https://clinicaltrials.gov/ct2/show/NCT03589794</obo:IAO_0000116>
        <obo:IAO_0000117>Ani Bernardi</obo:IAO_0000117>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000118>GLA-AF</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=66</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=22896687</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24465426</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24551202</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24556505</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26541135</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26862758</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=31174937</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=31690678</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32636844</obo:IAO_0000119>
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        <obo:VO_0005328>66</obo:VO_0005328>
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        <rdfs:label>GLA-AF vaccine adjuvant</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005425 -->

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        <obo:IAO_0000115>A cancer vaccine that is used against prostate cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0005426 -->

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        <obo:IAO_0000115>A cancer vaccine that is used against colorectal cancer</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005427 -->

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        <obo:IAO_0000115>A cancer vaccine that is used against lymphoma.</obo:IAO_0000115>
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        <rdfs:label>lymphoma vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0005428 -->

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        <obo:IAO_0000115>A cancer vaccine that is used against brain canceer.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005429 -->

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        <obo:IAO_0000115>A cancer vaccine that is used against liver canceer.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005430 -->

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        <obo:IAO_0000115>A cancer vaccine that is used against pancreatic canceer.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005434 -->

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        <obo:IAO_0000115>A recombinant viral vaccine vector that uses PVSRIPO, a recombinant nonpathogenic polio-rhinovirus chimera. PVSRIPO is an engineerable oncolytic virus whereas its internal ribosomal entry site element can be substituted to demolish its cytopathogenic effect. PVSRIPO has a natural inherent tropism for antigen-presenting cells (including dendritic cells and macrophages) due to the presence of the CD-155 receptor on their cellular surfaces. This enables it of inducing CD8+ T-cell mediate immune responses.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0005435 -->

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        <obo:IAO_0000115>A Comirnaty COVID-19 mRNA vaccine produced by Pfizer-BioNTech,which is a bivalent vaccine that is effective against the original strain of COVID-19 as well as the Omicron BA.1 variant.A non-US vaccine product.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Authorized by WHO 10/19/2022 - Counted toward immunity in US.Ref:https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx</rdfs:comment>
        <rdfs:label>SARS-COV-2 COVID-19 mRNA, bivalent, original/Omicron BA.1, Non-US Vaccine Product (Comirnaty Bivalent), Pfizer-BioNTech</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005436 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005436">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004987"/>
        <rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005436</metadata:prefixIRI>
        <obo:IAO_0000115>A Comirnaty COVID-19 mRNA vaccine utilizes Lipid Nanoparticle-Self-amplifying RNA technology, available as a bivalent boosters against the original strain of COVID-19 as well as the Omicron BA.1 variant produced by Pfizer (PF) with a dose of 30 mcg/0.3 mL to provide enhanced protection.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:36206167</obo:IAO_0000119>
        <obo:IAO_0000119>https://secure.medicalletter.org/TML-article-1660c</obo:IAO_0000119>
        <obo:IAO_0000119>https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0003099>Comirnaty</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>EUA authorized Pfizer adult bivalent booster ages 12+ yrs, original strain + omicron BA.4/BA.5. Not Authorized by WHO. Non-US Tradename for same formulation (Comirnaty Bivalent) counted toward immunity in US. Ref:https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx</rdfs:comment>
        <rdfs:label>SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, bivalent booster, preservative free, 30 mcg/0.3 mL dose, tris-sucrose formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005437 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005437">
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            </owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005437</metadata:prefixIRI>
        <obo:IAO_0000115>A Comirnaty COVID-19 mRNA vaccine utilizing Lipid Nanoparticle-Self-amplifying RNA technology against the original strain of COVID-19 without preservative ,which is produced by Pfizer (PF) with a dose of 30 mcg/0.3 mL.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, 30 mcg/0.3mL dose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005439 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005439">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005505"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005439</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that is made of immune globulin and used to immunize an individual against some disease(s).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150278/</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/706</obo:IAO_0000233>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005440 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005440">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005446"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005440</metadata:prefixIRI>
        <obo:IAO_0000118>anthrax immune globulin</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>181</obo:VO_0005438>
        <obo:VO_1000000>anthrax immune globulin</obo:VO_1000000>
        <obo:VO_1000001>anthrax immune globulin</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human anthrax immune globulin passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005441 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005441">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005445"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005441</metadata:prefixIRI>
        <obo:IAO_0000118>CMVIG</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>29</obo:VO_0005438>
        <obo:VO_1000000>cytomegalovirus immune globulin, intravenous</obo:VO_1000000>
        <obo:VO_1000001>CMVIG</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human cytomegalovirus immune globulin passive vaccine, intravenous</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005442 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005442">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005446"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005442</metadata:prefixIRI>
        <obo:IAO_0000115>Hepatitis A Immune Globulin passive vaccine is a
 passive vaccine that provides protection against hepatitis 
A through the passive transfer of an antibody. Hep A, IG provides
 temporary immunity to the virus for two to three months, if 
administered prior to exposure or within two weeks after exposure.</obo:IAO_0000115>
        <obo:IAO_0000118>Hep A,IG</obo:IAO_0000118>
        <obo:IAO_0000118>Hepatitis A immune globulin</obo:IAO_0000118>
        <obo:IAO_0000119>Stapleton, Jack T. &quot;Passive immunization against hepatitis A.&quot;
 Vaccine 10 (1992): S45-S47.</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>154</obo:VO_0005438>
        <obo:VO_1000000>Hepatitis A immune globulin</obo:VO_1000000>
        <obo:VO_1000001>Hep A, IG</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human hepatitis A immune globulin passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005443 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005443">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005446"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005443</metadata:prefixIRI>
        <obo:IAO_0000118>HBIG</obo:IAO_0000118>
        <obo:IAO_0000118>hepatitis B immune globulin</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>30</obo:VO_0005438>
        <obo:VO_1000000>hepatitis B immune globulin</obo:VO_1000000>
        <obo:VO_1000001>HBIG</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human hepatitis B immune globulin passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005444 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005444">
        <owl:equivalentClass>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005444</metadata:prefixIRI>
        <obo:IAO_0000118>IG</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_1000000>immune globulin, intramuscular</obo:VO_1000000>
        <obo:VO_1000001>IG</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human immune globulin passive vaccine, intramuscular</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005445 -->

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        <owl:equivalentClass>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005445</metadata:prefixIRI>
        <obo:IAO_0000118>IGIV</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>87</obo:VO_0005438>
        <obo:VO_1000000>immune globulin, intravenous</obo:VO_1000000>
        <obo:VO_1000001>IGIV</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human immune globulin passive vaccine, intravenous</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005446 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005446</metadata:prefixIRI>
        <obo:IAO_0000118>IG,unspecified formulation</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>14</obo:VO_0005438>
        <obo:VO_1000000>immune globulin, unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>IG, unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human immune globulin passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005447 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005447">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005446"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005447</metadata:prefixIRI>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>34</obo:VO_0005438>
        <obo:VO_1000000>rabies immune globulin</obo:VO_1000000>
        <obo:VO_1000001>RIG</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human rabies immune globulin passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005448 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005448">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005445"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005448</metadata:prefixIRI>
        <obo:IAO_0000118>RSV-IGIV</obo:IAO_0000118>
        <obo:IAO_0000118>respiratory syncytial virus immune globulin, intravenous</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>71</obo:VO_0005438>
        <obo:VO_1000000>respiratory syncytial virus immune globulin, intravenous</obo:VO_1000000>
        <obo:VO_1000001>RSV-IGIV</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human respiratory syncytial virus immune globulin passive vaccine, intravenous</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005449 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005449">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005451"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005449</metadata:prefixIRI>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>157</obo:VO_0005438>
        <obo:VO_1000000>Rho(D) Immune globulin - IM</obo:VO_1000000>
        <obo:VO_1000001>Rho(D) -IG IM</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human Rho(D) immune globulin - IM passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005450 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005450">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005451"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005450</metadata:prefixIRI>
        <obo:IAO_0000118>Rho(D) Immune globulin- IV or IM</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>156</obo:VO_0005438>
        <obo:VO_1000000>Rho(D) Immune globulin- IV or IM</obo:VO_1000000>
        <obo:VO_1000001>Rho(D)-IG</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human Rho(D) immune globulin- IV or IM passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005451 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005451">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005451</metadata:prefixIRI>
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        <obo:VO_0005438>159</obo:VO_0005438>
        <obo:VO_1000000>Rho(D) Unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>Rho(D) - Unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human Rho(D) immune globulin passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005452 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005452">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005446"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005452</metadata:prefixIRI>
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        <obo:VO_0005438>13</obo:VO_0005438>
        <obo:VO_0005438>180</obo:VO_0005438>
        <obo:VO_1000000>tetanus immune globulin</obo:VO_1000000>
        <obo:VO_1000001>TIG</obo:VO_1000001>
        <obo:VO_1000001>tetanus immune globulin</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human tetanus immune globulin passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005453 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005453">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005446"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005453</metadata:prefixIRI>
        <obo:IAO_0000118>vaccinia immune globulin</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>79</obo:VO_0005438>
        <obo:VO_1000000>vaccinia immune globulin</obo:VO_1000000>
        <obo:VO_1000001>vaccinia immune globulin</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human vaccinia immune globulin passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005454 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005454">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005446"/>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>36</obo:VO_0005438>
        <obo:VO_1000000>varicella zoster immune globulin</obo:VO_1000000>
        <obo:VO_1000001>VZIG</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human varicella zoster immune globulin passive vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005455 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005455">
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        <obo:VO_0005438>117</obo:VO_0005438>
        <obo:VO_1000000>varicella zoster immune globulin (Investigational New Drug)</obo:VO_1000000>
        <obo:VO_1000001>VZIG (IND)</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human varicella zoster immune globulin  passive vaccine (Investigational New Drug)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005456">
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    <!-- http://purl.obolibrary.org/obo/VO_0005457 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005458 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005459 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005464 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0005465 -->

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        <obo:IAO_0000116>Chemical Nature: emulsion
Mechanism of Action: adjuvanted antigen depot at injection site
Immune profile induced: Mixed Th1/Th2

Route of immunization: IM and SQ
Point of Contact: Peter Blackburn, MerciaPharma

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=23595760
https://www.ncbi.nlm.nih.gov/pubmed/?term=24783964
https://www.ncbi.nlm.nih.gov/pubmed/?term=34429319
https://www.ncbi.nlm.nih.gov/pubmed/?term=34926305

Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT02500680
https://clinicaltrials.gov/ct2/show/NCT02500680
https://clinicaltrials.gov/ct2/show/NCT03624062
https://clinicaltrials.gov/ct2/show/NCT02118077</obo:IAO_0000116>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Peter Blackburn</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>MAS-1</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=68</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT02118077</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT02500680</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT03624062</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=23595760</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24783964</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34429319</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34926305</obo:IAO_0000119>
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        <rdfs:label>MAS-1 vaccine adjuvant</rdfs:label>
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        <obo:IAO_0000115>A vaccine adjuvant that induces CD8 T cells and provides innate protection.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: small molecule
Mechanism of Action: Innate Immune Activation
Immune profile induced: Th1-biased

Route of immunization: SQ
Point of Contact: Taegyan Kang, Progeneer

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=36635335

Ongoing clinical trials: n/a</obo:IAO_0000116>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Taegyan Kang</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
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        <obo:IAO_0000115>A vaccine adjuvant that is a lipid-based vaccine adjuvent based on cationic surfactant dimethyl-dioctadecyl ammonium (DDA) combined with C-type lectin agonist monomycoloyl glycerol (MMG) and TLR3 agonist poly I:C. CAF09b is able to induce CD8+ T-cell response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Liposome
Mechanism of Action: n/a
Immune profile induced: n/a

Route of immunization: IN, IP, IM,
Point of Contact: Gabriel Kristian Pedersen, Staten Serum Institute (SSI)

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=35163772
https://www.ncbi.nlm.nih.gov/pubmed/?term=33352684
https://www.ncbi.nlm.nih.gov/pubmed/?term=35036074

Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT03715985</obo:IAO_0000116>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Gabriel Kristian Pedersen</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>CAF09b</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=76</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT03715985</obo:IAO_0000119>
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        <obo:IAO_0000115>A vaccine adjuvant that is a lipid-based nanosuspension of a synthetic TLR7/8 ligand that facilitates adsorption to aluminum oxyhydroxide via the structural properties of the helper lipid employed.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Mechanism of Action: Innate Immune Activation
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Valerie Soza, AAHI

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=27847326
https://www.ncbi.nlm.nih.gov/pubmed/?term=27847326
https://www.ncbi.nlm.nih.gov/pubmed/?term=36274085

Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT04177355
https://clinicaltrials.gov/ct2/show/NCT05781542
https://clinicaltrials.gov/ct2/show/NCT05471076
https://clinicaltrials.gov/ct2/show/NCT04915768
https://clinicaltrials.gov/ct2/show/NCT05781542</obo:IAO_0000116>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Valerie Soza</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>3M-052-AF</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=69</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT04177355</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT04915768</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT05471076</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT05781542</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=27847326</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=36274085</obo:IAO_0000119>
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        <obo:VO_0005328>69</obo:VO_0005328>
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        <obo:IAO_0000115>A vaccine adjuvant that reformulates Alhydrogel as a stable nanoparticle with the anionic polymer polyacrylic acid (PAA), leading to the induction of structure-dependent TH1 response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Mechanism of Action: Innate Immune Activation
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Valerie Soza, AAHI

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=30622742
https://www.ncbi.nlm.nih.gov/pubmed/?term=31930264</obo:IAO_0000116>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
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Mechanism of Action: Innate Immune Activation
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Valerie Soza, AAHI

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=35911728
https://www.ncbi.nlm.nih.gov/pubmed/?term=24551202
https://www.ncbi.nlm.nih.gov/pubmed/?term=34058388
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https://www.ncbi.nlm.nih.gov/pubmed/?term=36589712
https://www.ncbi.nlm.nih.gov/pubmed/?term=36323666

Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT05370040</obo:IAO_0000116>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Valerie Soza</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>NLC vaccine adjuvant</obo:IAO_0000118>
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        <obo:IAO_0000118>Nanostructured Lipid Carrier (NLC)</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=70</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT05370040</obo:IAO_0000119>
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        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
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        <obo:IAO_0000115>a malaria vaccine that protects against malaria caused by Plasmodium knowlesi.</obo:IAO_0000115>
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        <obo:IAO_0000115>A vaccine adjuvant is an oil-in-water emulsion that induces Th1-based immune response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Mechanism of Action: Innate Immune Activation
Immune profile induced: n/a

Route of immunization: IM
Point of Contact: Valerie Soza, AAHI

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=32983577
https://www.ncbi.nlm.nih.gov/pubmed/?term=35459225</obo:IAO_0000116>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Valerie Soza</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
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        <obo:IAO_0000115>A vaccine adjuvant is a gadoteridol-loaded cationic adjuvant formulation 01 that induced a Th1/Th17 type of immune response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Liposome system
Mechanism of Action: n/a
Immune profile induced: Th1/Th17

Route of immunization: IP, IM, IN, SQ, ID, SC, SL, intratracheal, endotracheal, Fish vaccination
Point of Contact: Gabriel Kristian Pedersen, Staten Serum Institute (SSI)

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=31539263
https://www.ncbi.nlm.nih.gov/pubmed/?term=30555488
https://www.ncbi.nlm.nih.gov/pubmed/?term=29699790
https://www.ncbi.nlm.nih.gov/pubmed/?term=34044110
https://www.ncbi.nlm.nih.gov/pubmed/?term=26394776
https://www.ncbi.nlm.nih.gov/pubmed/?term=18776936
https://www.ncbi.nlm.nih.gov/pubmed/?term=30291987
https://www.ncbi.nlm.nih.gov/pubmed/?term=21124731
https://www.ncbi.nlm.nih.gov/pubmed/?term=29358939
https://www.ncbi.nlm.nih.gov/pubmed/?term=33072125
https://www.ncbi.nlm.nih.gov/pubmed/?term=35585969
https://www.ncbi.nlm.nih.gov/pubmed/?term=26494626
https://www.ncbi.nlm.nih.gov/pubmed/?term=26379666
https://www.ncbi.nlm.nih.gov/pubmed/?term=35124896
https://www.ncbi.nlm.nih.gov/pubmed/?term=34358167
https://www.ncbi.nlm.nih.gov/pubmed/?term=29541075
https://www.ncbi.nlm.nih.gov/pubmed/?term=31130946
https://www.ncbi.nlm.nih.gov/pubmed/?term=31906072
https://www.ncbi.nlm.nih.gov/pubmed/?term=32106599
https://www.ncbi.nlm.nih.gov/pubmed/?term=19492047
https://www.ncbi.nlm.nih.gov/pubmed/?term=33422991
https://www.ncbi.nlm.nih.gov/pubmed/?term=28414746
https://www.ncbi.nlm.nih.gov/pubmed/?term=33066267
https://www.ncbi.nlm.nih.gov/pubmed/?term=27958370
https://www.ncbi.nlm.nih.gov/pubmed/?term=23308247
https://www.ncbi.nlm.nih.gov/pubmed/?term=30984200
https://www.ncbi.nlm.nih.gov/pubmed/?term=20505822
https://www.ncbi.nlm.nih.gov/pubmed/?term=27525651
https://www.ncbi.nlm.nih.gov/pubmed/?term=23873630

Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT00922363
https://clinicaltrials.gov/ct2/show/NCT01009762
https://clinicaltrials.gov/ct2/show/NCT02787109
https://clinicaltrials.gov/ct2/show/NCT01141205
https://clinicaltrials.gov/ct2/show/NCT03926728</obo:IAO_0000116>
        <obo:IAO_0000117>Ari Joffe</obo:IAO_0000117>
        <obo:IAO_0000117>Gabriel Kristian Pedersen</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>CAF01</obo:IAO_0000118>
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        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT00922363</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT01009762</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT01141205</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT02787109</obo:IAO_0000119>
        <obo:IAO_0000119>https://clinicaltrials.gov/ct2/show/NCT03926728</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=18776936</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=21124731</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=26394776</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=29358939</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=29699790</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=30291987</obo:IAO_0000119>
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        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34044110</obo:IAO_0000119>
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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>ovarian cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005494 -->

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        <owl:equivalentClass>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000177"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000177"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005494</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is developed against renal cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>renal cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005495 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005495">
        <owl:equivalentClass>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000177"/>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
                    </owl:Restriction>
                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005495</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is developed against sarcoma cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>sarcoma cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005496 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005496">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
                    </owl:Restriction>
                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005496</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is developed against esophageal cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>esophageal cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005497 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005497">
        <owl:equivalentClass>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11934"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11934"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005497</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is developed against head and neck cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11934"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>head and neck cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005498 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005498">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000177"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9261"/>
                    </owl:Restriction>
                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005498</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is developed against nasopharyngeal cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9261"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>nasopharyngeal cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005499 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005499">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000177"/>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000177"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005429"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005499</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is developed against hepatocellular carcinoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatocellular carcinoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005501 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005501">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005501</metadata:prefixIRI>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum MSA2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005502 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005502">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005502</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that prevents or reduce the transmission of a disorder within a target host or among a population by inducing or modifying specific adaptive immune responses against the antigens present in the vaccine.</obo:IAO_0000115>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/695</obo:IAO_0000233>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>transmission-blocking vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005503 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005503">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005503</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that prevents or treats specific disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Charles Tapley Hoyt</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/619</obo:IAO_0000233>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vaccine against disease</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005504 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005504">
        <owl:equivalentClass>
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                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
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                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000718"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0100026"/>
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                                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005504</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine against an infectious disease caused by specific pathogen(s).</obo:IAO_0000115>
        <obo:IAO_0000116>Note that all infectious diseases are caused by some pathogens, so &apos;infectious disease vaccine&apos; and &apos;vaccine against pathogen infection&apos; are basically synonyms.</obo:IAO_0000116>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Charles Tapley Hoyt</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>infectious disease vaccine</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine against pathogen</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine against pathogen infection</obo:IAO_0000118>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/619</obo:IAO_0000233>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/747</obo:IAO_0000233>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0050117"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vaccine against infectious disease</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005505 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005505">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005505</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that is developed and produced by specific technology or method.</obo:IAO_0000115>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Charles Tapley Hoyt</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/619</obo:IAO_0000233>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vaccine by mode of production</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005506 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005506">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGG_0000000002"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005506</metadata:prefixIRI>
        <obo:IAO_0000115>Gene expressing a protein which serves, either in whole or in part, as an antigen within a cancer vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/677</obo:IAO_0000233>
        <oboInOwl:inSubset>gene</oboInOwl:inSubset>
        <rdfs:label>canvaxgen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005507 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005507">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005507</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine adjuvant that is primarily composed of protein and actives innate immune pathways to induce a mixed Th1/Th2 response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: protein
Mechanism of Action: Activation of innate immune pathways
Immune profile induced: Th1/Th2

Route of immunization: SC, IN, SQ
Point of Contact: Marcel Wuethrich, University of Wisconsin

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=28793349
https://www.ncbi.nlm.nih.gov/pubmed/?term=31900406

Ongoing clinical trials:
none</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Marcel Wuethrich</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000118>Bl-Eng2</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:28793349</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:31900406</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=97</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/730</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>97</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Bl-Eng2 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005508 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005508">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001354"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0005312"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005508</metadata:prefixIRI>
        <obo:IAO_0000115>Combination vaccine adjuvant contains both Bl-Eng2 and adjuplex vaccine adjuvants and is able to induce a mixed Th1/Th2 response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Protein, Combination adjuvant
Mechanism of Action: Activation of innate immune pathways
Immune profile induced: Th1/Th2

Route of immunization: IN
Point of Contact: Marcel Wuethrich, University of Wisconsin

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=33735218

Ongoing clinical trials:
none</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Marcel Wuethrich</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000118>Bl-Eng2+Adjuplex</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:33735218</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=98</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/731</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>98</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Bl-Eng2+Adjuplex vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005509 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005509</metadata:prefixIRI>
        <obo:IAO_0000115>Nucleic acid vaccine adjuvant that targets on cytokine receptor to induce a Th1-based response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: nucleic acid
Mechanism of Action: Cytokine Receptor
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Romain Micol, Combined Therapeutics

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=39047117

Ongoing clinical trials:
none</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Romain Micol</obo:IAO_0000117>
        <obo:IAO_0000118>IL-12-MOP (CTX-1796)</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:39047117</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=100</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/740</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>100</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>IL-12-MOP (CTX-1796) vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005510 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005510</metadata:prefixIRI>
        <obo:IAO_0000115>Botryococcene oil-in-water emulsion vaccine adjuvant made by EVAX Inc., which targets to induce a mixed Th1/Th2 response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Emulsion
Mechanism of Action: Botryococcene oil-in-water emulsion
Immune profile induced: Mixed Th1/Th2
Route of immunization: SQ
Point of Contact: Chase Kempinski , EVAX Inc.
Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=33051497
Ongoing clinical trials:
none</obo:IAO_0000116>
        <obo:IAO_0000117>Chase Kempinski</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000118>EVAX-B</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:33051497</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=101</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/759</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>101</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>EVAX-B vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005511 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005511</metadata:prefixIRI>
        <obo:IAO_0000115>Squalene oil-in-water emulsion vaccine adjuvant made by EVAX Inc., which targets to induce a mixed Th1/Th2 response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Emulsion
Mechanism of Action: Squalene oil-in-water emulsion
Immune profile induced: Mixed Th1/Th2

Route of immunization: SQ
Point of Contact: Chase Kempinski , EVAX Inc.

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=33051497

Ongoing clinical trials:
none</obo:IAO_0000116>
        <obo:IAO_0000117>Chase Kempinski</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000118>EVAX-S</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:33051497</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=102</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/760</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>102</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>EVAX-S vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005512 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005512">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000366"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005512</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine adjuvant based on VesiVax® liposome.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: VesiVax® liposome
Mechanism of Action: none
Immune profile induced: none

Route of immunization: SQ prime and IN boost, SQ, Combination sub-cheek, IN and ID, IN prime and sub-cheek boosts
Point of Contact: Gary Fujii, Molecular Express

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=16713037
https://www.ncbi.nlm.nih.gov/pubmed/?term=17981684
https://www.ncbi.nlm.nih.gov/pubmed/?term=19835825
https://www.ncbi.nlm.nih.gov/pubmed/?term=21545821
https://www.ncbi.nlm.nih.gov/pubmed/?term=23313243
https://www.ncbi.nlm.nih.gov/pubmed/?term=26312747
https://www.ncbi.nlm.nih.gov/pubmed/?term=27997339
https://www.ncbi.nlm.nih.gov/pubmed/?term=28922045
https://www.ncbi.nlm.nih.gov/pubmed/?term=29420901
https://www.ncbi.nlm.nih.gov/pubmed/?term=3568049

Ongoing clinical trials:
none</obo:IAO_0000116>
        <obo:IAO_0000117>Gary Fujii</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Molecular Express</obo:IAO_0000117>
        <obo:IAO_0000118>ME-F-1051 (VesiVax®)</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:16713037</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:19835825</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:21545821</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:23313243</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:26312747</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:27997339</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:28922045</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:29420901</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:3568049</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=104</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/784</obo:IAO_0000233>
        <obo:VO_0005328>104</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>ME-F-1051 (VesiVax®) vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005513 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005513">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000366"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005513</metadata:prefixIRI>
        <obo:IAO_0000115>Liposome-based vaccine adjuvant with TLR4 agonist to induce a mixed Th1/Th2 response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Natural compound - Liposome formulation with TLR4 agonist
Mechanism of Action: none
Immune profile induced: Mixed Th1/Th2

Route of immunization: SQ, Combination of sub-cheek, IN and ID, IN prime with sub-cheek boosts,
Point of Contact: Gary Fujii, Molecular Express

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=23313243
https://www.ncbi.nlm.nih.gov/pubmed/?term=26312747
https://www.ncbi.nlm.nih.gov/pubmed/?term=27997339
https://www.ncbi.nlm.nih.gov/pubmed/?term=35680499
https://www.ncbi.nlm.nih.gov/pubmed/?term=19835825
https://www.ncbi.nlm.nih.gov/pubmed/?term=21545821
https://www.ncbi.nlm.nih.gov/pubmed/?term=16713037

Ongoing clinical trials:
none</obo:IAO_0000116>
        <obo:IAO_0000117>Gary Fujii</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Molecular Express</obo:IAO_0000117>
        <obo:IAO_0000118>ME-F-1122</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:16713037</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:19835825</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:21545821</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:23313243</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:26312747</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:27997339</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:35680499</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=103</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/785</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>103</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>ME-F-1122 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005514 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005514">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0006109"/>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005514</metadata:prefixIRI>
        <obo:IAO_0000115>Short class B CpG-containing sequence with phosphorothioate-linked nucleotides that is able to induce a Th1-biased response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Nucleic acid
Mechanism of Action: CpG 1018 is a short class B CpG-containing sequence with phosphorothioate-linked nucleotides
Immune profile induced: Th1-biased

Route of immunization: IN, IM
Point of Contact: Ben Wizel, Dynavax

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=24464743
https://www.ncbi.nlm.nih.gov/pubmed/?term=33649322
https://www.ncbi.nlm.nih.gov/pubmed/?term=33873199
https://www.ncbi.nlm.nih.gov/pubmed/?term=33888840
https://www.ncbi.nlm.nih.gov/pubmed/?term=38570604
https://www.ncbi.nlm.nih.gov/pubmed/?term=35927132
https://www.ncbi.nlm.nih.gov/pubmed/?term=35869085
https://www.ncbi.nlm.nih.gov/pubmed/?term=37703367
https://www.ncbi.nlm.nih.gov/pubmed/?term=39231203

Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/ACTRN12624000064505
https://clinicaltrials.gov/ct2/show/NCT06334393
https://clinicaltrials.gov/ct2/show/NCT04177355
https://clinicaltrials.gov/ct2/show/NCT04672395
https://clinicaltrials.gov/ct2/show/NCT05188677
https://clinicaltrials.gov/ct2/show/NCT05011526
https://clinicaltrials.gov/ct2/show/NCT05364242
https://clinicaltrials.gov/ct2/show/NCT04956224
https://clinicaltrials.gov/ct2/show/NCT0486456
https://clinicaltrials.gov/ct2/show/ACTRN12620001177943
https://clinicaltrials.gov/ct2/show/NCT00251394
https://clinicaltrials.gov/ct2/show/NCT01282762
https://clinicaltrials.gov/ct2/show/NCT00346086
https://clinicaltrials.gov/ct2/show/NCT06569823
https://clinicaltrials.gov/ct2/show/NCT05245838
https://clinicaltrials.gov/ct2/show/NCT05506969</obo:IAO_0000116>
        <obo:IAO_0000117>Ben Wizel</obo:IAO_0000117>
        <obo:IAO_0000117>Dynavax</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>CpG 1018</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:24464743</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:33649322</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:33873199</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:33888840</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:35869085</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:35927132</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:37703367</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:38570604</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:39231203</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=105</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/787</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>105</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>CpG 1018 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005563 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005563">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005563</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that targets against a microbial eukaryote caused disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>microbial eukaryotic vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005800 -->

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            </owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005800</metadata:prefixIRI>
        <obo:IAO_0000115>A Inactivated vaccine that immunizes against Neospora caninum protozoa.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>N. caninum Killed Protozoa Vaccine</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum killed protozoa vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005801 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005801</metadata:prefixIRI>
        <obo:IAO_0000115>A Inactivated vaccine that immunizes against Toxoplasma gondii trypmastigote.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>CTLVECNS</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6065</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6065</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CTLVECNS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005802 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005802</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine encoding a1-giardin and CWP2 that immunizes against Giardi lamblia trophozoite.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>G. lamblia bivalent DNA vaccine encoding a1-giardin and CWP2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5993</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5993</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Giardia lamblia bivalent DNA vaccine encoding a1-giardin and CWP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005803 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005803</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine encoding a-enolase that immunizes against Giardi lamblia trophozoite.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>G. lamblia vaccine encoding a-enolase</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5991</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5991</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Giardia lamblia vaccine encoding a-enolase</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005804 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005804</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine encoding a1-giardin that immunizes against Giardi lamblia trophozoite.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>G. lamblia vaccine encoding a1-giardin</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5989</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5989</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5741"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Giardia lamblia vaccine encoding a1-giardin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005805 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005805">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005805</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine expressing VSPH7 that immunizes against Giardi lamblia trophozoite.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>G. lamblia vaccine using attenuated Salmonella vaccine expressing VSPH7</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6004</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>6004</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Giardia lamblia vaccine using attenuated Salmonella vaccine expressing VSPH7</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005806 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005806">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005806</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine p52(-)/p36(-) GAP that immunizes against Plasmodium falciparum sporozoite.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>p52(-)/p36(-) GAP</obo:IAO_0000118>
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        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>5952</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>p52(-)/p36(-) GAP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005807 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005807</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine Pb(PfCS@UIS4) that immunizes against Plasmodium falciparum sporozoite.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5988</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>5988</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pb(PfCS@UIS4) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005808 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005808</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine PfSPZ that immunizes against Plasmodium falciparum sporozoite.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>PfSPZ</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5950</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>5950</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PfSPZ vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005809 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005809">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005809</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine RH-AMA1KO that immunizes against Toxoplasma gondii trypmastigote.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>RH-AMA1KO</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6069</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>6069</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>RH-AMA1KO vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005810 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0005810">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005810</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine with GRA17 mutant that immunizes against Toxoplasma gondii trypmastigote.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii GRA17 mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6082</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6082</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA17 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005811 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005811</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine irradiated sterilised tachyzoites that immunizes against Toxoplasma gondii trypmastigote.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii irradiated sterilised tachyzoites</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6090</obo:IAO_0000119>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii irradiated sterilised tachyzoites vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005812 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005812</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine with LDH1 and LDH2 mutant that immunizes against Toxoplasma gondii trypmastigote.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii LDH1 and LDH2 mutant vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6087</obo:IAO_0000119>
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        <obo:VO_0001818>6087</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii LDH1 and LDH2 mutant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005813 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0005813</metadata:prefixIRI>
        <obo:IAO_0000115>A Live attenuated vaccine with DSCG adjuvant that immunizes against Toxoplasma gondii trypmastigote.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>UV-attenuated Toxoplasma gondii with DSCG adjuvant</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6091</obo:IAO_0000119>
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        <obo:VO_0001818>6091</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>UV-attenuated Toxoplasma gondii vaccine with DSCG adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006000 -->

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        <obo:IAO_0000118>adenovirus unspecified formulation</obo:IAO_0000118>
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        <obo:VO_1000000>adenovirus vaccine, unspecified formulation</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>adenovirus vaccine unspecified formulation</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006001 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006001</metadata:prefixIRI>
        <obo:IAO_0000118>botulinum antitoxin</obo:IAO_0000118>
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        <obo:VO_1000000>botulinum antitoxin</obo:VO_1000000>
        <obo:VO_1000001>botulinum antitoxin</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>botulinum antitoxin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006002 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <obo:IAO_0000118>cholera unspecified formulation</obo:IAO_0000118>
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        <obo:VO_0005438>26</obo:VO_0005438>
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        <obo:VO_1000000>cholera vaccine, unspecified formulation</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>cholera vaccine unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006003 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006003</metadata:prefixIRI>
        <obo:IAO_0000118>cholera BivWC</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0006004 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006005 -->

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        <obo:IAO_0000118>diphtheria antitoxin</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>diphtheria antitoxin</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006006 -->

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        <obo:IAO_0000118>Hib unspecified formulation</obo:IAO_0000118>
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        <obo:VO_0005438>17</obo:VO_0005438>
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        <obo:VO_1000000>Haemophilus influenzae type b vaccine, conjugate unspecified formulation</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae type b vaccine conjugate unspecified formulation</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006007 -->

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        <obo:IAO_0000118>Hib (PRP-D)</obo:IAO_0000118>
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        <rdfs:label>Haemophilus influenzae type b vaccine PRP-D conjugate</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006008 -->

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        <obo:IAO_0000118>Hep A live attenuated</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0006009 -->

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        <obo:IAO_0000118>Hep A adult</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0006010 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006011 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis A vaccine pediatric/adolescent dosage 3 dose schedule</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006012 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006012</metadata:prefixIRI>
        <obo:IAO_0000118>Hep A unspecified formulation</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        <obo:VO_0005438>85</obo:VO_0005438>
        <obo:VO_0010151>40213302</obo:VO_0010151>
        <obo:VO_1000000>hepatitis A vaccine, unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>Hep A, unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis A vaccine unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010439"/>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006013</metadata:prefixIRI>
        <obo:IAO_0000118>HepB recombinant 3-antigen Al(OH)3</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
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        <obo:VO_0005438>220</obo:VO_0005438>
        <obo:VO_0010151>905414</obo:VO_0010151>
        <obo:VO_1000000>Hepatitis B vaccine (recombinant), 3-antigen, Al(OH)3 adjuvanted</obo:VO_1000000>
        <obo:VO_1000001>HepB recombinant, 3-antigen, Al(OH)3</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B vaccine (recombinant) 3-antigen Al(OH)3 adjuvanted</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006014</metadata:prefixIRI>
        <obo:IAO_0000118>Hep B adolescent/high risk infant</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0005438>42</obo:VO_0005438>
        <obo:VO_0010151>40213305</obo:VO_0010151>
        <obo:VO_1000000>hepatitis B vaccine, adolescent/high risk infant dosage</obo:VO_1000000>
        <obo:VO_1000001>Hep B, adolescent/high risk infant</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B vaccine adolescent/high risk infant dosage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006015">
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006015</metadata:prefixIRI>
        <obo:IAO_0000118>Hep B unspecified formulation</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>45</obo:VO_0005438>
        <obo:VO_0010151>40213308</obo:VO_0010151>
        <obo:VO_1000000>hepatitis B vaccine, unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>Hep B, unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B vaccine unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006016">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006016</metadata:prefixIRI>
        <obo:IAO_0000118>Hep C</obo:IAO_0000118>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        <obo:VO_0005438>58</obo:VO_0005438>
        <obo:VO_0010151>40213309</obo:VO_0010151>
        <obo:VO_1000000>hepatitis C vaccine</obo:VO_1000000>
        <obo:VO_1000001>Hep C</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human hepatitis C vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006017</metadata:prefixIRI>
        <obo:IAO_0000118>Hep E</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        <obo:VO_0005438>59</obo:VO_0005438>
        <obo:VO_0010151>40213310</obo:VO_0010151>
        <obo:VO_1000000>hepatitis E vaccine</obo:VO_1000000>
        <obo:VO_1000001>Hep E</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human hepatitis E vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000727"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006018</metadata:prefixIRI>
        <obo:IAO_0000118>herpes simplex 2</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        <obo:VO_0005438>60</obo:VO_0005438>
        <obo:VO_0010151>40213311</obo:VO_0010151>
        <obo:VO_1000000>herpes simplex virus, type 2 vaccine</obo:VO_1000000>
        <obo:VO_1000001>herpes simplex 2</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>herpes simplex virus type 2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006019</metadata:prefixIRI>
        <obo:IAO_0000118>typhus historical</obo:IAO_0000118>
        <obo:VO_0005438>131</obo:VO_0005438>
        <obo:VO_0010151>40213247</obo:VO_0010151>
        <obo:VO_1000000>Historical record of a typhus vaccination</obo:VO_1000000>
        <obo:VO_1000001>typhus, historical</obo:VO_1000001>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>Historical record of a typhus vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006020">
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        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0010446"/>
        <rdfs:label>obsolete HPV unspecified formulation</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006021">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010448"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006021</metadata:prefixIRI>
        <obo:IAO_0000118>Rabies - IM Diploid cell culture</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
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        <obo:VO_0005438>175</obo:VO_0005438>
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        <obo:VO_1000001>Rabies - IM Diploid cell culture</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006022 -->

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        <obo:IAO_0000118>influenza nasal unspecified formulation</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza nasal unspecified formulation</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006023 -->

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        <obo:IAO_0000116>Retired CVX CODE</obo:IAO_0000116>
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        <obo:VO_0005438>15</obo:VO_0005438>
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        <obo:VO_1000000>influenza virus vaccine, split virus (incl. purified surface antigen)-retired CODE</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus vaccine split virus (incl. purified surface antigen)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006024 -->

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        <obo:IAO_0000118>influenza unspecified formulation</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus vaccine unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006025 -->

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        <obo:IAO_0000118>influenza whole</obo:IAO_0000118>
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        <rdfs:label>influenza virus vaccine whole virus</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006026 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006027 -->

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        <obo:IAO_0000115>A viral vaccine that protects against infection with Mammarenavirus juninense.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0006028 -->

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        <rdfs:label>leprosy vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006029 -->

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        <obo:IAO_0000118>meningococcal A polysaccharide (non-US)</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0006030 -->

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        <obo:IAO_0000118>meningococcal AC polysaccharide (non-US)</obo:IAO_0000118>
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        <obo:VO_0005438>192</obo:VO_0005438>
        <obo:VO_0010151>706108</obo:VO_0010151>
        <obo:VO_1000000>meningococcal AC polysaccharide vaccine (non-US)</obo:VO_1000000>
        <obo:VO_1000001>meningococcal AC polysaccharide (non-US)</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal AC polysaccharide vaccine (non-US)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006031">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006031</metadata:prefixIRI>
        <obo:IAO_0000118>meningococcal ACWY unspecified formulation</obo:IAO_0000118>
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        <obo:VO_0005438>108</obo:VO_0005438>
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        <obo:VO_1000000>meningococcal ACWY vaccine, unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>meningococcal ACWY, unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal ACWY vaccine unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006032">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006032</metadata:prefixIRI>
        <obo:IAO_0000118>meningococcal B unspecified</obo:IAO_0000118>
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        <obo:VO_0005438>164</obo:VO_0005438>
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        <obo:VO_1000000>meningococcal B, unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>meningococcal B, unspecified</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal B unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006033">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006033</metadata:prefixIRI>
        <obo:IAO_0000118>meningococcal C conjugate</obo:IAO_0000118>
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        <obo:VO_0005438>103</obo:VO_0005438>
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        <obo:VO_1000000>meningococcal C conjugate vaccine</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal C conjugate vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006034">
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        <obo:IAO_0000118>meningococcal unknown serogroups</obo:IAO_0000118>
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        <obo:VO_1000000>meningococcal vaccine of unknown formulation and unknown serogroups</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal vaccine of unknown formulation and unknown serogroups</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006035 -->

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        <obo:IAO_0000118>meningococcal polysaccharide (groups A C Y W-135) TT conjugate</obo:IAO_0000118>
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        <obo:VO_1000001>meningococcal conjugate quadrivalent, MenACWY-TT (MCV4)</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal polysaccharide (groups A C Y W-135) tetanus toxoid conjugate vaccine 0.5mL dose preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006036 -->

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        <obo:IAO_0000118>meningococcal MCV4 unspecified formulation</obo:IAO_0000118>
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        <obo:VO_1000000>Meningococcal, MCV4, unspecified conjugate formulation(groups A, C, Y and W-135)</obo:VO_1000000>
        <obo:VO_1000001>meningococcal MCV4, unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Meningococcal MCV4 unspecified conjugate formulation(groups A C Y and W-135)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006037 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006038 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006039 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006040 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006041 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006044 -->

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        <obo:IAO_0000118>Pneumococcal Conjugate unspecified formulation</obo:IAO_0000118>
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        <obo:VO_0005438>152</obo:VO_0005438>
        <obo:VO_0010151>40213200</obo:VO_0010151>
        <obo:VO_1000000>Pneumococcal Conjugate, unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>Pneumococcal Conjugate, unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pneumococcal Conjugate unspecified formulation</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006045 -->

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        <obo:IAO_0000118>rabies intradermal injection</obo:IAO_0000118>
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        <obo:VO_1000000>rabies vaccine, for intradermal injection</obo:VO_1000000>
        <obo:VO_1000001>rabies, intradermal injection</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabies vaccine for intradermal injection</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006046 -->

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        <obo:IAO_0000118>rabies unspecified formulation</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabies vaccine unspecified formulation</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006047 -->

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        <obo:IAO_0000118>RSV-MAb (new)</obo:IAO_0000118>
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        <rdfs:label>respiratory syncytial virus monoclonal antibody (motavizumab) intramuscular</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006048 -->

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        <obo:IAO_0000118>RSV-MAb</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0006049 -->

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        <obo:IAO_0000115>Vaccine that protects against group A Streptococcus infection causing rheumatic fever.</obo:IAO_0000115>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0006050 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0006051 -->

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        <obo:IAO_0000118>rotavirus live tetravalent vaccine</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0006065 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006066 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006067 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006068 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006069 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006070 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006071 -->

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        <obo:IAO_0000118>COVID-19 PS Non-US Vaccine (Jiangsu Province Centers for Disease Control and Prevention)</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (Jiangsu Province Centers for Disease Control and Prevention)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006072 -->

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        <obo:IAO_0000118>COVID-19 PS Non-US Vaccine (Anhui Zhifei Longcom Biopharm + Inst of Micro Chinese Acad of Sciences)</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (Anhui Zhifei Longcom Biopharmaceutical + Institute of Microbiology Chinese Academy of Sciences)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006073 -->

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        <rdfs:label>SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (Anhui Zhifei Longcom Zifivax)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006074 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006075 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006076 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006077 -->

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        <obo:VO_0005438>112</obo:VO_0005438>
        <obo:VO_1000000>tetanus toxoid, unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>tetanus toxoid, unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>tetanus toxoid unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006078 -->

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        <obo:IAO_0000118>Tick-borne encephalitis vaccine (non-US)</obo:IAO_0000118>
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        <obo:VO_1000000>Tick-borne encephalitis vaccine (non-US)</obo:VO_1000000>
        <obo:VO_1000001>Tick-borne encephalitis vaccine (non-US)</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tick-borne encephalitis vaccine (non-US)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006079 -->

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        <obo:IAO_0000118>Tick-borne encephalitis inactivated PF 0.25mL</obo:IAO_0000118>
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        <obo:VO_1000000>Tick-borne encephalitis vaccine, inactivated, preservative free, 0.25mL dose</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tick-borne encephalitis vaccine inactivated preservative free 0.25mL dose</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006080 -->

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        <obo:IAO_0000118>Tick-borne encephalitis inactivated PF 0.5mL</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tick-borne encephalitis vaccine inactivated preservative free 0.5mL dose</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006081 -->

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        <obo:IAO_0000118>Tick-borne encephalitis unspecified</obo:IAO_0000118>
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        <obo:VO_1000000>Tick-borne encephalitis vaccine, unspecified</obo:VO_1000000>
        <obo:VO_1000001>Tick-borne encephalitis, unspecified</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tick-borne encephalitis vaccine unspecified</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006082 -->

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        <obo:IAO_0000118>Typhoid conjugate vaccine (TCV)</obo:IAO_0000118>
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        <obo:VO_1000000>Typhoid conjugate vaccine (non-US)</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid conjugate vaccine (non-US)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006083 -->

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        <obo:IAO_0000118>typhoid parenteral AKD (U.S. military)</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0006084 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006085 -->

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        <obo:IAO_0000118>typhoid unspecified formulation</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0006086 -->

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        <obo:IAO_0000118>vaccinia (smallpox) diluted</obo:IAO_0000118>
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        <obo:VO_1000000>vaccinia (smallpox) vaccine, diluted</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>vaccinia (smallpox) vaccine diluted</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006087 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006087</metadata:prefixIRI>
        <obo:IAO_0000118>Vaccinia smallpox monkeypox vaccine live PF SQ or ID injection</obo:IAO_0000118>
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        <obo:VO_1000000>Vaccinia, smallpox monkeypox vaccine, live attenuated, preservative free, subcutaneous or intradermal injection</obo:VO_1000000>
        <obo:VO_1000001>Vaccinia, smallpox Mpox vaccine live, PF, SQ or ID injection</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaccinia smallpox monkeypox vaccine live attenuated preservative free subcutaneous or intradermal injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006088 -->

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        <obo:IAO_0000118>VEE unspecified formulation</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Venezuelan equine encephalitis vaccine unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006089 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0006090 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>tetravalent dengue fever vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006091 -->

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        <obo:IAO_0000118>Ebola unspecified</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola unspecified</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006092 -->

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        <obo:IAO_0000115>A combination vaccine adjuvant that is liposome-based adjuvant of a synthetic TLR agonist and saponin induced a Th1-biased immune response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Combination adjuvant
Mechanism of Action: n/a
Immune profile induced: Th1-biased
Route of immunization: IM
Point of Contact: Maria Lawrenz, Vaccine Formulation Institute</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Maria Lawrenz</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>LMQ</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=78</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=36119058</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=36634821</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=37029167</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/614</obo:IAO_0000233>
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        <obo:VO_0005328>78</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>LMQ vaccine adjuvant</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0006093 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006093</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant that is a peptide which is able to induce Th1/Th2/Th17 immune responses through the mechanism of selectively activates C5aR1 on mononuclear phagocytes vs neutrophils.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Other - Peptide
Mechanism of Action: (Primary) Selectively activates C5aR1 on mononuclear phagocytes vs neutrophils
Immune profile induced: Th1/Th2/Th17
Route of immunization: IP, IV
Point of Contact: Joseph Vetro, University of Nebraska Medical Center</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Joseph Vetro</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>CPDI-02</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=40</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=11710544</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=19836478</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=20965299</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/615</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005376"/>
        <obo:VO_0005328>40</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>CPDI-02 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006094 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006094</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant with a Toll-like receptor 9 (TLR9)-active oligonucleotide that is able to induce Th1/Th2 immune responses.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Nucleic acid
Mechanism of Action: TLR9 agonist
Immune profile induced: Mixed Th1/Th2
Route of immunization: IM, SQ
Point of Contact: Nikolai Petrovsky, Vaxine LTD
</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nikolai Petrovsky</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>CpG55.2</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=10</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=24554695</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=27387453</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32156809</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=32418798</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=33479242</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34399628</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34420786</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/?term=34456075</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/616</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>10</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>CpG55.2 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006095 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006095</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant that includes AS01-mimic, Immune Stimulating Complex (ISCOM) with a TLR4 agonist.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Combination adjuvant
Mechanism of Action: Cytokine induction in draining lymph nodes with increased lymph flow and lymph antigen accumulation
Immune profile induced: Mixed Th1/Th2
Route of immunization: s.c. / i.m. / i.n.
Point of Contact: Katarzyna Kaczmarek Michaels, Massachusetts Institute of Technology
Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=34860581
https://www.ncbi.nlm.nih.gov/pubmed/?term=36131022
https://www.ncbi.nlm.nih.gov/pubmed/?term=34878851</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Katarzyna Kaczmarek Michaels</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>SMNP</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=77</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/632</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>77</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>SMNP vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006096 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006096</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant that is an AS01-mimic, liposomal adjuvant of a TLR4 agonist and saponin.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature:
- Natural compound
- Synthetic derivative of natural compound
- Combination adjuvant
Mechanism of Action: MPLA: TLR4 agonist QS21: Sugar-lawn likely recog. by lectins to facilitate uptake by M_, DCs, etc
Immune profile induced: Mixed Th1/Th2
Route of immunization: ID, IM
Point of Contact: Mangala Rao, Walter Reed Army Institute of Research
Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=34202178
https://www.ncbi.nlm.nih.gov/pubmed/?term=31827000
https://www.ncbi.nlm.nih.gov/pubmed/?term=34470866
https://www.ncbi.nlm.nih.gov/pubmed/?term=35632473
https://www.ncbi.nlm.nih.gov/pubmed/?term=36417525
https://www.ncbi.nlm.nih.gov/pubmed/?term=34914540
https://www.ncbi.nlm.nih.gov/pubmed/?term=32881968
https://www.ncbi.nlm.nih.gov/pubmed/?term=26372857
https://www.ncbi.nlm.nih.gov/pubmed/?term=36055874
https://www.ncbi.nlm.nih.gov/pubmed/?term=34202178
https://www.ncbi.nlm.nih.gov/pubmed/?term=36679887
https://www.ncbi.nlm.nih.gov/pubmed/?term=36934088
https://www.ncbi.nlm.nih.gov/pubmed/?term=34903722
https://www.ncbi.nlm.nih.gov/pubmed/?term=31775762
https://www.ncbi.nlm.nih.gov/pubmed/?term=28596090
https://www.ncbi.nlm.nih.gov/pubmed/?term=31151801
https://www.ncbi.nlm.nih.gov/pubmed/?term=34711815
https://www.ncbi.nlm.nih.gov/pubmed/?term=34159328
Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT04268420
https://clinicaltrials.gov/ct2/show/NCT04296279
https://clinicaltrials.gov/ct2/show/NCT04784767
https://clinicaltrials.gov/ct2/show/NCT05500417
https://clinicaltrials.gov/ct2/show/NCT04826094
https://clinicaltrials.gov/ct2/show/NCT04658667
https://clinicaltrials.gov/ct2/show/NCT05423418</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Mangala Rao</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>ALFQ</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=79</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/633</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>79</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>ALFQ vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006097 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006097</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant which is a small molecule TLR agonist that drives a mixed Th1/Th2 response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature:
Small molecule
Mechanism of Action: Innate immune activation
Immune profile induced: Mixed Th1/Th2
Route of immunization: IM
Point of Contact: Dennis Carson, UCSD</obo:IAO_0000116>
        <obo:IAO_0000117>Dennis Carson</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>2G023A</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=81</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/648</obo:IAO_0000233>
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        <obo:VO_0005328>81</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>2G023A vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006098 -->

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        <obo:IAO_0000115>A vaccine adjuvant, a small molecule TLR agonist that drives a mixed Th1/Th2 response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature:
Small molecule
Mechanism of Action: Innate immune activation
Immune profile induced: Mixed Th1/Th2
Route of immunization: IM
Point of Contact: Dennis Carson, UCSD</obo:IAO_0000116>
        <obo:IAO_0000117>Dennis Carson</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>2G053</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=80</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/649</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>80</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>2G053 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006099">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006099</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant of a synthetic TLR agonist and aluminum salt.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature:
- Synthetic derivative of natural compound
- Combination adjuvant
- Mineral salt
Mechanism of Action: Innate Immune Activation
Immune profile induced: Th1-biased
Route of immunization: SQ, IM
Point of Contact: Valerie Soza, Access to Advanced Health Institute (AAHI)
Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=37454145
https://www.ncbi.nlm.nih.gov/pubmed/?term=24556505
https://www.ncbi.nlm.nih.gov/pubmed/?term=28828575
https://www.ncbi.nlm.nih.gov/pubmed/?term=30013570
https://www.ncbi.nlm.nih.gov/pubmed/?term=24211167
https://www.ncbi.nlm.nih.gov/pubmed/?term=23933525
https://www.ncbi.nlm.nih.gov/pubmed/?term=34597297
https://www.ncbi.nlm.nih.gov/pubmed/?term=36996185
https://www.ncbi.nlm.nih.gov/pubmed/?term=28464026
Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT03910972
https://clinicaltrials.gov/ct2/show/NCT02126462
https://clinicaltrials.gov/ct2/show/NCT02839161
https://clinicaltrials.gov/ct2/show/NCT03110757
https://clinicaltrials.gov/ct2/show/NCT02337855
https://clinicaltrials.gov/ct2/show/NCT01717950
https://clinicaltrials.gov/ct2/show/NCT02476773
https://clinicaltrials.gov/ct2/show/NCT01261130
https://clinicaltrials.gov/ct2/show/NCT01385189
https://clinicaltrials.gov/ct2/show/NCT03172975</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Valerie Soza</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>GLA-Alum</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=83</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/650</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>83</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>GLA-Alum vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006100 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006100</metadata:prefixIRI>
        <obo:IAO_0000115>A combination vaccine adjuvant of a synthetic TLR4 agonist and aluminum salt.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature:
- Synthetic derivative of natural compound
- Combination adjuvant
- Mineral salt
Mechanism of Action: Innate Immune Activation
Immune profile induced: Th1-biased
Route of immunization: IM
Point of Contact: Valerie Soza, Access to Advanced Health Institute (AAHI)
Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=26901122
https://www.ncbi.nlm.nih.gov/pubmed/?term=32983577</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Valerie Soza</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>SLA-Alum</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=82</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/651</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>82</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>SLA-Alum vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006101">
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        <obo:IAO_0000115>An emulsion vaccine adjuvant that includes squalene-based oil-in-water emulsion.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Emulsion
Mechanism of Action: n/a
Immune profile induced: Mixed Th1/Th2
Route of immunization: IM, SQ
Point of Contact: Valerie Soza, Access to Advanced Health Institute (AAHI)
Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=19679214
https://www.ncbi.nlm.nih.gov/pubmed/?term=22896687
https://www.ncbi.nlm.nih.gov/pubmed/?term=28429728
https://www.ncbi.nlm.nih.gov/pubmed/?term=37495191
https://www.ncbi.nlm.nih.gov/pubmed/?term=36256646
https://www.ncbi.nlm.nih.gov/pubmed/?term=28089141
Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT03330899
https://clinicaltrials.gov/ct2/show/NCT01612000
https://clinicaltrials.gov/ct2/show/NCT02464163
https://clinicaltrials.gov/ct2/show/NCT02464163</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Valerie Soza</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Stable Emulsion (SE)</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=84</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/652</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>84</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>Stable Emulsion (SE) vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006102 -->

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        <obo:IAO_0000115>A nucleic acid vaccine adjuvant that is primarily composed of oligonucleotide.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>oligonucleotide vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006103 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006103</metadata:prefixIRI>
        <obo:IAO_0000115>An emulsion vaccine adjuvant that is squalene-based adjuvant, induces T follicular helper cells and humoral immune responses via alpha-tocopherol component.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Emulsion
Mechanism of Action: n/a
Immune profile induced: Th1-biased

Route of immunization: IM
Point of Contact: Maki Hayase, Shionogi &amp;Co., Ltd

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=36372670
https://www.ncbi.nlm.nih.gov/pubmed/?term=36891311
https://www.ncbi.nlm.nih.gov/pubmed/?term=36460696
https://www.ncbi.nlm.nih.gov/pubmed/?term=35691872

Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT05212948</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Maki Hayase</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000118>A-910823</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:36891311</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=90</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/666</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>90</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>A-910823 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006104 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006104</metadata:prefixIRI>
        <obo:IAO_0000115>An oligonucleotide vaccine adjuvant that is a TLR9-agonistic adjuant containing a CpG oligonucleotide annealed to a complementary strand with an amphiphilic chain unit, acts as a potent cancer vaccine adjuvant by targeting draining lymph nodes.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Oligonucleotide
Mechanism of Action: Activation of TLR9 signaling pathway
Immune profile induced: Th1-biased

Route of immunization: IM, SQ
Point of Contact: Maki Hayase, Shionogi &amp;Co., Ltd

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=35003132
https://www.ncbi.nlm.nih.gov/pubmed/?term=37243234

Ongoing clinical trials:
N/A</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Maki Hayase</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000118>S-540956</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:35003132</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:37243234</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=91</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/667</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>91</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>S-540956 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006105 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006105</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant which is a small molecule adjuvant that is able to induce a mixed Th1/Th2 response and active innate immunity. </obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Small molecule
Mechanism of Action: Activation of innate immunity
Immune profile induced: Mixed Th1/Th2

Route of immunization: IM, ID
Point of Contact: Ofer Levy, Precision Vaccines Program at Boston Children&apos;s Hospital</obo:IAO_0000116>
        <obo:IAO_0000116>It may actually be the world’s first small-molecule TLR3 agonist.</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Ofer Levy</obo:IAO_0000117>
        <obo:IAO_0000118>Precision Vaccines Program (PVP)-057</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=86</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/676</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>86</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>precision vaccines program-057 vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006106 -->

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        <obo:IAO_0000115>An emulsion vaccine adjuvant that targets on TLR-agonist. It is a nucleic acid-based adjuvant for chemical nature.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Nucleic acid, Emulsion
Mechanism of Action: Innate Immune Activation, preferential uptake by APCs
Immune profile induced: Th1-biased
Definition: TLR-agonist for target; nucleic acid-based adjuvant for chemical nature

Route of immunization: SQ, IN, IM
Point of Contact: Madhavan Nallani, ACM Biolabs

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=34618423
https://www.ncbi.nlm.nih.gov/pubmed/?term=36223228

Ongoing clinical trials:
https://clinicaltrials.gov/ct2/show/NCT05385991</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Madhavan Nallani</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000118>ACM-CpG</obo:IAO_0000118>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=92</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/690</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>92</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>ACM-CpG vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006107 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0006107">
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0006107</metadata:prefixIRI>
        <obo:IAO_0000115>A particulate antigen delivery system vaccine adjuvant derived from Cowpea mosaic virus that is able to induce a Th1-biased response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: Nucleoprotein complex
Mechanism of Action: recognized by PRRs
Immune profile induced: Th1-biased

Route of immunization: Intratumoral, intraperitoneally , IV
Point of Contact: Nicole Steinmetz, University of California, San Diego

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=26689376
https://www.ncbi.nlm.nih.gov/pubmed/?term=37844250

Ongoing clinical trials:
none</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nicole Steinmetz</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118>Cowpea mosaic virus</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:26689376</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:37844250</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=93</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/684</obo:IAO_0000233>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000147"/>
        <obo:RO_0001000 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12264"/>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005309"/>
        <obo:VO_0005328>93</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>cowpea mosaic virus vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006108 -->

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        <obo:IAO_0000115>A nucleic acid vaccine adjuvant that targets on TLR3 agonist to induce a mixed Th1/Th2 response.</obo:IAO_0000115>
        <obo:IAO_0000116>Chemical Nature: dsRNA
Mechanism of Action: TLR3 agonist
Immune profile induced: Mixed Th1/Th2
category: nucleic-acid based adjuvant (TLR-agonist)
synthetic derivative of natural compound
Route of immunization: IM
Point of Contact: Seungbin Cha, NA Vaccine Institute

Pubmed References:
https://www.ncbi.nlm.nih.gov/pubmed/?term=36761735
https://www.ncbi.nlm.nih.gov/pubmed/?term=38136298

Ongoing clinical trials:
none</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Nilufer kosar</obo:IAO_0000117>
        <obo:IAO_0000117>Seungbin Cha</obo:IAO_0000117>
        <obo:IAO_0000118>Nexavant</obo:IAO_0000118>
        <obo:IAO_0000119>Pubmed:36761735</obo:IAO_0000119>
        <obo:IAO_0000119>Pubmed:38136298</obo:IAO_0000119>
        <obo:IAO_0000119>VAC: https://vac.niaid.nih.gov/view?id=94</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/694</obo:IAO_0000233>
        <obo:VO_0005312 rdf:resource="http://purl.obolibrary.org/obo/VO_0005311"/>
        <obo:VO_0005328>94</obo:VO_0005328>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>nexavant vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0006109 -->

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        <obo:IAO_0000115>A vaccine adjuvant that is primarily composed of nucleic acid.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine adjuvant</oboInOwl:inSubset>
        <rdfs:label>nucleic acid vaccine adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007000 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007000</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant oncolytic adenovirus encoding the immunohematopoietic cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with potential antineoplastic activity. Upon administration, the oncolytic adenovirus selectively infects and replicates in tumor cells, which may result in tumor cells lysis. Synergistically, GM-CSF (sargramostim) expressed by the oncolytic adenovirus may promote a cytotoxic T cell response against tumor cells harboring the oncolytic adenovirus, resulting in an immune-mediated tumor cell death.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C48412</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00109655</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:28530155</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5475</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/75</obo:IAO_0000233>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5475</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CSF-2</rdfs:comment>
        <rdfs:label>Oncolytic Adenovirus Encoding GM-CSF Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007001 -->

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        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007001</metadata:prefixIRI>
        <obo:IAO_0000115>A non-replicating recombinant adenovirus type 5 (Ad5)-vector encoding the gene for interferon alpha-2b (IFN_2b) and the gene transfer enhancement agent Syn 3, with potential antineoplastic activity. Upon intravesical administration, recombinant adenovirus-interferon with Syn3 transfects both cancerous and normal bladder cells, and the adenovirus secretes interferon (IFN_2b) into the bladder. IFN exerts a direct antitumor killing effect and a bystander effect, thereby killing adjacent, non-transfected cancerous bladder cells. Syn 3 enhances the ability of the adenoviral vector to transfect cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C104743</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02773849</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:28834453</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5047</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/322</obo:IAO_0000233>
        <obo:OGG_0000000006>3440</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5047</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IFNA2</rdfs:comment>
        <rdfs:label>Recombinant Adenovirus-Interferon/Syn3 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007002 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007002</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine adjuvant consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF binds to specific cell surface receptors on various immuno-hematopoietic cell types, enhancing their proliferation and differentiation and stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Administration of recombinant fowlpox GM-CSF vaccine adjuvant may induce an immune response against tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2686</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00072137</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:15780740</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4994</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/328</obo:IAO_0000233>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4994</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:label>Recombinant Fowlpox GM-CSF Vaccine Adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007003</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine derived from cytomegalovirus (CMV) antigens with potential immunostimulating activity. Intradermal administration of the PEP-CMV vaccine may stimulate the immune system to mount a specific helper and cytotoxic T-lymphocyte (CTL) response against CMV-infected tumor cells. Infection with the herpesvirus CMV may play a significant role in tumor cell initiation and progression as well as chemoresistance.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C107243</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02864368</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:31806885</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5259</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/118</obo:IAO_0000233>
        <obo:OGG_0000000006>18826</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5259</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: pp65(Lcp 1)</rdfs:comment>
        <rdfs:label>PEP-CMV Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007004</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a human epidermal growth factor receptor variant III (EGFRvIIi)-specific peptide conjugated to the non-specific immunomodulator keyhole limpet hemocyanin (KLH) with potential antineoplastic activity. Vaccination with rindopepimut may elicit a cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing EGFRvIII. EGFRvIII, a functional variant of EGFR that is not expressed in normal tissues, was originally discovered in glioblastoma multiforme (GBM) and has also been found in various other cancers such as breast, ovarian, metastatic prostate, colorectal, and head and neck cancers. EGFRvIII contains an 83 amino acid deletion in its extracellular domain and has been shown to transform NIH/3T3 mouse embryonic fibroblast cells in vitro.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C69076</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01498328</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:28844499</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5032</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/120</obo:IAO_0000233>
        <obo:OGG_0000000006>1956</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5032</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EGFR</rdfs:comment>
        <rdfs:label>PF-04948568 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007005</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C29786</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:21078216</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5192</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/324</obo:IAO_0000233>
        <obo:OGG_0000000006>945006</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5192</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: lacZ</rdfs:comment>
        <rdfs:label>Recombinant Adenovirus-LacZ Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007006</metadata:prefixIRI>
        <obo:IAO_0000115>A personalized peptide-based cancer vaccine comprised of one or two de novo synthesized patient-specific tumor-mutated peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB mutated tumor-specific peptides vaccine therapy APVAC2 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the selected mutated tumor-associated peptides, which results in decreased GB growth. These peptides are specifically selected and synthesized based on the expression of the patient‚Äö√†√∂‚àö√òs own mutated tumor-associated antigens, which were detected during individual tumor genome sequencing.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C116332</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02149225</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5086</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5086</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Synthetic Glioblastoma Mutated Tumor-specific Peptides Vaccine Therapy APVAC2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007007</metadata:prefixIRI>
        <obo:IAO_0000115>A personalized peptide-based cancer vaccine comprised of five to ten peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB tumor-associated peptides vaccine therapy APVAC1 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the tumor associated peptides, and results in decreased GB growth. The peptides are derived from a glioma actively-personalized vaccine consortium (GAPVAC) warehouse and are specifically selected based on the patient&apos;s expression of tumor-associated antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C116331</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02149225</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5231</obo:IAO_0000119>
        <obo:OGG_0000000006>1956</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5231</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EGFR</rdfs:comment>
        <rdfs:label>Synthetic Glioblastoma Tumor-associated Peptides Vaccine Therapy APVAC1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007008 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007008</metadata:prefixIRI>
        <obo:IAO_0000115>An orally available DNA cancer vaccine containing an attenuated strain of the bacterium Salmonella typhimurium encoding murine vascular endothelial growth factor receptor 2 (VEGFR-2) (VXM01), with potential immunomodulating, anti-angiogenic and antineoplastic activity. Upon oral administration and successful transduction, VEGFR-2 DNA vaccine VXM01 expresses VEGFR-2 in addition to inducing the expression of T-cell activation markers, such as CD25, interleukin-2, the early T-cell activation antigen CD69 and the lymphocyte function-associated antigen LFA-2. The immune response targets the fast growing VEGFR-2 expressing endothelial cells found in the tumor vasculature, thereby blocking angiogenesis which may ultimately inhibit tumor cell proliferation. VEGFR-2 is a receptor tyrosine kinase overexpressed on proliferating endothelial cells in the tumor vasculature.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C99378</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02718443</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:29632710</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5521</obo:IAO_0000119>
        <obo:OGG_0000000006>3791</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5521</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KDR</rdfs:comment>
        <rdfs:label>VEGFR-2 DNA Vaccine VXM01</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007009 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007009</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer peptide vaccine comprised of a human leukocyte antigen (HLA) A2/A3 restricted HER2/neu (ERBB2) peptide from the extracellular domain of the HER2 protein (E75 peptide) and combined with the immunoadjuvant granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunomodulating and antineoplastic activity. Upon intradermal injection, nelipepimut-S plus GM-CSF vaccine may induce a specific cytotoxic T-lymphocyte (CTL) response against HER2/neu-expressing tumor cell types. HER2/neu, a tumor-associated antigen and a member of the epidermal growth factor receptor family of tyrosine kinases, is overexpressed in various tumor cell types. GM-CSF potentiates the antitumor immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C99228</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02636582</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:33485895</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5363</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/54</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5363</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>Nelipepimut-S Plus GM-CSF Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007010 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007010</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of one or more long, synthetic peptides derived from patient-specific breast cancer tumor-associated antigens (TAAs), with potential immunomodulating and antineoplastic activities. Upon intramuscular administration of the personalized synthetic long peptide breast cancer vaccine, the peptides stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the TAAs, which results in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C121947</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02427581</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5348</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5348</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Personalized Synthetic Long Peptide Breast Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007011">
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007011</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA cancer vaccine encoding the intracellular domain (ICD) of the HER-2/neu proto-oncogene. Upon administration and after cellular uptake by skin or muscle cells, the pNGVL3-hICD vaccine plasmid expresses the HER-2/neu protein, which, after intracellular processing, may elicit both antigen-specific cytotoxic T-lymphocyte (CTL) and humoral immune responses against tumor cells expressing HER-2. The HER-2/neu ICD protein is highly immunogenic and, as a subdominant epitope, may be associated with decreased immune tolerance.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C61146</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT05163223</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5040</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/122</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5040</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>pNGVL3-hICD Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007012 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007012</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C29785</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11590241</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5530</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/320</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5530</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Recombinant Adenovirus-Cre Recombinase Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007013</metadata:prefixIRI>
        <obo:IAO_0000115>An immunotherapeutic composed of the Wilms tumor 1 (WT1) and an as of yet undisclosed adjuvant, with potential antineoplastic activity. Upon administration, the immune system may be stimulated to exert a cytotoxic T-lymphocyte (CTL) response against WT1-expressing tumor cells. The adjuvant stimulates the immune system&apos;s response to WT1. WT1, a tumor-associated antigen (TAA) and transcription factor, is overexpressed in a variety of tumor cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C116880</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01220128</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:30562862</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5297</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/326</obo:IAO_0000233>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5297</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>Recombinant Anti-WT1 Immunotherapeutic GSK2302024A Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007014</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a truncated recombinant HER2 peptide (dHER2) with potential antineoplastic activity. Upon administration, recombinant dHER2 vaccine may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against tumor cells that overexpress the HER2 protein, resulting in tumor cell lysis. The HER2 protein is a tumor-associated antigen (TAA) that is overexpressed in a variety of cancers. dHER2 includes the extracellular domain (ECD) and a part of the intracellular domain (ICD) of the HER2 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C49177</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00140738</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26975189</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5241</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5241</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>Recombinant dHER2 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007015">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007015</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing autologous dendritic cells pulsed with a fusion product of an epitope of human tumor-associated epithelial mucin 1 (MUC1) antigen and the vaccine adjuvant mannan (oxidized mannose), with potential antineoplastic activity. When the modified dendritic cells are returned to the patient, they may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the MUC1 antigen, resulting in tumor cell lysis. Addition of manna in this vaccine, enhances immune recognition. MUC1 antigen, a high-molecular-weight transmembrane glycoprotein, is overexpressed on many tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C102782</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00004156</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9656453</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5077</obo:IAO_0000119>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5077</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>Recombinant Human MUC1-Oxidized Polymannose-pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007016</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the 5T4 fetal oncoprotein (MVA-h5T4). Vaccination with recombinant modified vaccinia Ankara-5T4 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing 5T4 fetal oncoprotein antigen, resulting in tumor cell lysis. The MVA viral vector, derived from the replication-competent strain Ankara, is a highly attentuated, replication-defective vaccinia strain incapable of virion assembly.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C49087</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00227474</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:18990081</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5058</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/337</obo:IAO_0000233>
        <obo:OGG_0000000006>7162</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5058</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TPBG</rdfs:comment>
        <rdfs:label>Recombinant Modified Vaccinia Ankara-5T4 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007017</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccinia virus based vaccine expressing human tumor associated epithelial mucin (DF3 antigen; MUC1). MUC1 antigen, a membrane bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in various tumors such as breast, prostate, and ovarian cancers. This vaccine could be used in development of immunotherapeutics against cancers expressing MUC1.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2510</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00071942</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9101412</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5281</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/338</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5281</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>Recombinant Vaccinia DF3/MUC1 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007018 -->

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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007018</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine containing a recombinant vaccinia virus that encodes the gene for human mucin-1, a tumor-associated antigen. Upon administration, recombinant vaccinia-MUC-1 vaccine may elicit a MUC-1-specific cytotoxic T cell response against tumor cells bearing MUC-1.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2732</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00071942</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12898638</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5321</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/347</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5321</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>Recombinant Vaccinia-MUC-1 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007019 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007019</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine containing a pancarcinoma carbohydrate antigen conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Sialylated Tn antigen (sTn) is a monosaccharide glycan usually O-linked to serine or threonine residues of mucins found on most epithelial cancers. Conjugation with KLH, a hapten carrier and an immunostimulant, improves host immune responses. Vaccination with sTn-KLH vaccine may produce antibodies and elicit a cytotoxic T lymphocyte (CTL) response against those tumor cells expressing sTn, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C1690</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00003638</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:23983823</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5425</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/361</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5425</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: sialyl-Tn</rdfs:comment>
        <rdfs:label>Sialyl Tn-KLH Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007020">
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007020</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine comprised of a synthetic Sialyl-Tn antigen linked to the protein carrier, keyhole limpet hemocyanin (KLH), administered with immunostimulant, Detox. Vaccination with STn-KLH plus Detox may elicit an IgG-based anti-STn antibody response and ultimately a cytotoxic T-cell response against STn-expressing cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2501</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00003638</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7690215</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5061</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/363</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5061</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: sialyl-Tn</rdfs:comment>
        <rdfs:label>STn-KLH plus Detox Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007021">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007021</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of multiple synthetic breast cancer peptides and the adjuvant tetanus toxoid helper peptide emulsified in the adjuvant Montanide ISA-51 with immunopotentiation activity. Vaccination with this cancer vaccine may elicit a specific cytotoxic T-lymphocyte response against breast cancer cells. Synthetic breast cancer peptides may stimulate the immune response against cells that produce breast cancer markers such as erbB2 (HER2/neu) while tetanus toxoid helper peptide binds to class II MHC molecules as a nonspecific vaccine helper epitope, resulting in a long-term immunopotentiation by increasing the helper T-cell response. Montanide ISA-51, also known as incomplete Freund&apos;s adjuvant or IFA, is a stabilized water-in-oil emulsion adjuvant containing mineral oil with mannide oleate added as a surfactant that non-specifically stimulates cell-mediated immune responses to antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C61076</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00304096</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5271</obo:IAO_0000119>
        <obo:OGG_0000000006>6007</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5271</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: RHD</rdfs:comment>
        <rdfs:label>Synthetic Breast Cancer Peptides-Tetanus Toxoid-Montanide ISA-51 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007022</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine containing a clustered pancarcinoma carbohydrate antigen conjugated with keyhole limpet hemocyanin (KLH) with potential antineoplastic activity. Alpha-N-acetylgalactosamine (Tn) is a monosaccharide usually O-linked to serine or threonine residues of mucins found on most epithelial cancers with the highest expression on prostate cancer. This vaccine contains the Tn epitope cluster (c) that is synthesized by linking 3 copies of the Tn epitope on a threonine backbone to achieve the essential immunogenic structure. KLH is a hapten carrier and serves as an immunostimulant to improve immune recognition. Vaccination with Tn(c)-KLH vaccine may produce antibodies and elicit a cytotoxic T lymphocyte (CTL) response against those tumor cells expressing Tn antigen, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2474</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00030823</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9579798</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5025</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5025</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Tn(c)-KLH Conjugate Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007023 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007023</metadata:prefixIRI>
        <obo:IAO_0000115>A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma. (NCIT_C85466).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C85466</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00900809</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:18425107</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5026</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/50</obo:IAO_0000233>
        <obo:OGG_0000000006>107653060</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5026</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IL12</rdfs:comment>
        <rdfs:label>Natural Killer Cells ZRx101 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007024 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007024</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of an immunogenic peptide derived from the cancer-testis antigen (NY-ESO-1), an antigen found in normal testis and various tumors. Vaccination with NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response to cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2657</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT05479045</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:24397899</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5206</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/55</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5206</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:label>NY-ESO-1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007025 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007025</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1 with potential immunostimulating and antitumor activities. Upon administration, NY-ESO-1 plasmid DNA cancer vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the NY-ESO-1 antigen, resulting in tumor cell lysis. NY-ESO-1 is a tumor associated antigen (TAA) found in normal testes and expressed on the surfaces of various tumor cells, including melanoma, breast, bladder, prostate, lung, ovarian, and hepatocellular tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C62452</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00199849</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:15102697</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:21900253</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5283</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/56</obo:IAO_0000233>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/58</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3908"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5283</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:label>NY-ESO-1 plasmid DNA cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007026 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007026</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of a recombinant form of the tumor antigen NY-ESO-1 and glucopyranosyl lipid adjuvant (GLA)-stable emulsion (GLA-SE), with potential antineoplastic and immunomodulating activities. Upon intramuscular injection, the adjuvant portion of the NY-ESO-1/GLA-SE vaccine ID-G30 binds to toll-like receptor subtype 4 (TLR-4) expressed on dendritic cells (DCs), monocytes, macrophages and B cells. The activated DCs present the NY-ESO-1 antigen to Th1 CD4 T-lymphocytes. This leads to the induction of cytotoxic T lymphocytes (CTLs) and the killing of NY-ESO-1-expressing tumor cells. This vaccine also induces specific antibody responses and increases the production of inflammatory cytokines.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C113432</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02015416</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:31069460</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5445</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/85</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>7099</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5409"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5445</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:comment>Gene name: TLR4</rdfs:comment>
        <rdfs:label>NY-ESO-1/GLA-SE vaccine ID-G305AmN</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007027 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007027</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant nonapeptide used as an antineoplastic vaccine. NY-ESO-1b peptide vaccine contains the amino acid sequence SLLMWITQC, derived from the cancer-testis tumor antigen (NY-ESO-1), which is expressed on tumor cells of many different types, including melanomas. Vaccination with this peptide vaccine may elicit strong humoral and cellular immune responses to NY-ESO-1-expressing cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C68999</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00199836</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:15501973</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5428</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/112</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5428</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:label>NY-ESO-1b peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007028 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007028</metadata:prefixIRI>
        <obo:IAO_0000115>A tumor-associated antigen belonging to the family of immunogenic testicular proteins that are aberrantly expressed in human cancers in a lineage-nonspecific fashion. Reverse transcription-PCR analysis showed NY-ESO-1 mRNA expression in a variable proportion of a wide array of human cancers, including melanoma, breast cancer, bladder cancer, prostate cancer, and hepatocellular carcinoma; and restricted expression in normal tissues, with high-level mRNA expression found only in testis and ovary tissues. The gene for NY-ESO-1 maps to Xq28 and codes for an 18-kDa protein having no homology with any known protein. NY-ESO-1 elicits a strong, integrated humoral and cellular immune response in a high proportion of patients with NY-ESO-1-expressing tumors and is under investigation as a cancer immunotherapy agent.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C26680</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5182</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/76</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5182</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:label>NY-ESO-B vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007029 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007029</metadata:prefixIRI>
        <obo:IAO_0000115>An E1B-55kDa-deleted adenovirus that is able to selectively replicate in and lyse TP53-deficient human tumor cells. After tumor cell lysis, released viruses infect neighboring tumor cells, tripping a chain of ONYX-015-mediated tumor cell cytotoxicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2830</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00006106</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11892945</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5486</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/73</obo:IAO_0000233>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11934"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8557"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0023644"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5486</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TP53</rdfs:comment>
        <rdfs:label>ONYX-015 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007030">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007030</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide-based cancer vaccine composed of amino acids 264 to 272 of the wild-type protein encoded by the P53 gene. p53 peptide vaccine may elicit an HLA-A2.1-restricted cytotoxic T lymphocyte immune response against tumor cells that overexpress p53 protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C1986</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00001827</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:24583792</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5255</obo:IAO_0000119>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5255</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TP53</rdfs:comment>
        <rdfs:label>p53 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007031 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007031</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide-based vaccine containing a pan HLA DR-binding epitope (PADRE) fused to a cytomegalovirus (CMV) peptide epitope, with potential anti-viral and immunomodulating activities. Upon administration, PADRE-CMV fusion peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against CMV in the CMV-infected host. The synthetic peptide PADRE is a universal helper T cell epitope.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C78820</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00722839</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:22402037</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5441</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5441</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>PADRE-CMV fusion peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007032 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007032</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic HIV-1 envelope peptide that was developed for use as a vaccine. Vaccination with PCLUS 3-18MN may stimulate the host immune system to mount cytotoxic T lymphocyte (CTL) and T helper cell responses, and induce the production of neutralizing antibodies.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2786</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00001386</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:10546852</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5451</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/115</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5451</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>PCLUS 3-18MN vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007033 -->

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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007033</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic HIV-1 envelope peptide that was developed for use as a vaccine. Vaccination with PCLUS 6.1-18MN may stimulate the host immune system to mount cytotoxic T lymphocyte (CTL) and T helper cell responses, and induce the production of neutralizing antibodies.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2787</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00001386</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:10546852</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5443</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/116</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5443</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>PCLUS 6.1-18MN vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007034</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of Her2/neu peptides incorporated into microspheres of poly (lactide-co-glycolide) (PLGA), a biodegradable polymer. Poly microsphere encapsulated HER2/neu oral vaccine has been investigated for use in immunotherapy for tumors positive for HER-2/neu, a tumor associated antigen that is overexpressed in various cancers, including breast and ovarian cancer.‚Äö√†√∂‚àö¬ß</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2718</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02795988</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:29448628</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5176</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5176</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>poly microsphere encapsulated HER2/neu oral vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007035">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007035</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing a RAS oncogene-encoded peptide with potential antineoplastic activity. RAS peptide cancer vaccine may stimulate a RAS peptide-specific antitumoral T-cell cytotoxic immune response, resulting in an inhibition of tumor cell proliferation and tumor cell death.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2438</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00019006</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:33016924</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5320</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/189</obo:IAO_0000233>
        <obo:OGG_0000000006>3845</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5320</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KRAS</rdfs:comment>
        <rdfs:label>RAS peptide cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007036</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the stimulatory molecule transgene B7-1. Recombinant fowlpox-B7.1 (rF-B7.1) vaccine may enhance antigen presentation and activate antitumoral cytotoxic T-cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2666</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00030693</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12969559</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5424</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/329</obo:IAO_0000233>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5424</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:label>recombinant Fowlpox-B7.1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007037 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007037</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). This agent may enhance CEA presentation to antigen presenting cells (APC) and activate cytotoxic T-cells against CEA-expressing tumors.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2620</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00028496</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5049</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/330</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5049</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:label>recombinant Fowlpox-CEA(6D)/TRICOM vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007038">
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007038</metadata:prefixIRI>
        <obo:IAO_0000115>A whole, heat-killed, recombinant Saccharomyces cerevisiae yeast-based vaccine genetically altered to express the carcinoembryonic antigen (CEA) peptide 610D with potential immunostimulating and antineoplastic activities. Upon administration, recombinant Saccharomyces cerevisia-CEA(610D) vaccine GI-6207 may stimulate a host cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells, which may result in tumor cell lysis. CEA, a tumor associated antigen, is overexpressed on a wide variety of human cancer cells including colorectal, gastric, lung, breast and pancreatic cancer cells. CEA 610D encodes for 9 amino acids (605-613) in which aspartate is substituted for asparagine at position 610 (610D) in order to strengthen the induction of the CTL response against CEA-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C82371</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00924092</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:22862954</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5152</obo:IAO_0000119>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5152</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>recombinant Saccharomyces Cerevisia-CEA(610D)-expressing vaccine GI-6207</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007039 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007039">
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007039</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of recombinant vaccinia virus encoding the tumor-associated antigen carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-CEA(6D)-TRICOM vaccine stimulates the host immune system to mount a T-cell response against tumor cells expressing the CEA antigen. The use of TRICOM in the vaccine may elicit a greater antitumor cytotoxic T lymphocyte (CTL) immune response compared to the use of vaccinia-CEA alone.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2619</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00217373</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27581603</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5037</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/342</obo:IAO_0000233>
        <obo:OGG_0000000006>111518</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5037</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Cea-Mouse</rdfs:comment>
        <rdfs:label>recombinant Vaccinia-CEA(6D)-TRICOM vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007040">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007040</metadata:prefixIRI>
        <obo:IAO_0000115>An admixture of recombinant vaccinia virus encoding MUC-1 and recombinant vaccinia virus encoding the murine T-cell co-stimulatory molecule B7.1. MUC-1 is a glycosylated mucin that is overexpressed in breast, lung, pancreatic, prostate, stomach, colon, and ovarian carcinomas. Vaccination with MUC-1 in combination with B7.1 may enhance the cytotoxic T cell (CTL) immune response to tumors expressing MUC-1, compared to vaccination with MUC-1 alone.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29409</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9101412</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5326</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/348</obo:IAO_0000233>
        <obo:OGG_0000000006>12519</obo:OGG_0000000006>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5326</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Cd80</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>recombinant Vaccinia-MUC1-B7 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007041">
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007041</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant vaccinia viral vector encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1, an antigen found in normal testis and various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. Vaccination with recombinant vaccinia- NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C48419</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00112957</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:29773080</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5389</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/349</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5389</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:label>recombinant Vaccinia-NY-ESO-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007042 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007042</metadata:prefixIRI>
        <obo:IAO_0000115>A replication-incompetent, pathotropic, tumor matrix (collagen)-targeted, retroviral vector encoding an N-terminal deletion mutant form of the cyclin G1 gene with potential antineoplastic activity. Under the control of a hybrid long-terminal repeat/cytomegalovirus (CMV) promoter, retrovector encoding mutant anti-cyclin G expresses the mutant cyclin G1 construct, resulting in disruption of tumor cell cyclin G1 activity and decreased cellular proliferation and angiogenesis. This agent preferentially targets collagen of the tumor matrix because of the incorporation of the collagen-binding domain of von Willebrand factor (vWF) on the retrovector surface. Exploiting the collagen-targeting mechanism of vWF permits delivery of the retrovector to tumor sites where angiogenesis and collagen matrix exposure occur.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C49082</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00505271</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5437</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/355</obo:IAO_0000233>
        <obo:OGG_0000000006>900</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5437</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CCNG1</rdfs:comment>
        <rdfs:label>retrovector encoding mutant Anti-Cyclin G1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007043 -->

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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007043</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous dendritic cell (DC) vaccine loaded with tumor-associated antigens (TAAs) derived from survivin, p53 and human epidermal growth factor receptor 2 (HER2 or ERBB2), with immunostimulating and antineoplastic activities. Upon administration, this DC vaccine may elicit a potent cytotoxic T-cell (CTL) response against tumor cells expressing these TAAs, resulting in tumor cell death. Survivin, p53 and HER2 are essential in neoplastic growth, and are considered to be universal tumor antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C114285</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00978913</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16096014</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5180</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:OGG_0000000006>373110</obo:OGG_0000000006>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5180</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:comment>Gene name: Survivin</rdfs:comment>
        <rdfs:comment>Gene name: p53</rdfs:comment>
        <rdfs:label>survivin/p53/HER2 antigen-loaded autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007044">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007044</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine containing a 15-mer peptide (DLAQMFFCFKELEGW), with C to M alteration at amino acid position 57, derived from the anti-apoptosis protein survivin, and conjugated with keyhole limpet hemocyanin (KLH), with potential immunopotentiating and antineoplastic activities. Upon subcutaneous administration of SVN53-67/M57-KLH peptide vaccine, this peptide is able to bind both HMC class I and II molecules and may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) as well as a T-helper cell response against survivin-expressing cancer cells. This may result in decreased tumor cell proliferation and ultimately tumor cell death. Survivin, a member of the inhibitor of apoptosis (IAP) family, expressed during embryonic development while absent in most normal adult cells, is upregulated in a variety of human cancers; its expression in tumors is associated with a more aggressive phenotype, decreased survival, and increased resistance to chemotherapy. KLH may enhance immune recognition and may promote an enhanced response. As SVN53-67 is weakly immunogenic in humans, the M57 alteration may lead to greater affinity towards HLA-A*0201 and thus an enhanced antitumor immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C95705</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02334865</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27576783</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5008</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/405</obo:IAO_0000233>
        <obo:OGG_0000000006>373110</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5008</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Survivin</rdfs:comment>
        <rdfs:label>SVN53-67/M57-KLH peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007045">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007045</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine consisting of a plasmid encoding the full-length sequence of the tumor-associated antigen (TAA) human telomerase reverse transcriptase (hTERT), which is the catalytic subunit of human telomerase and synthesizes telomeric DNA at the chromosome ends, containing two immunogenic mutations, with potential immunostimulating and antineoplastic activities. Upon intradermal vaccination of the hTERT-encoding DNA vaccine INO-1400 in combination with electroporation, hTERT protein is expressed and activates the immune system to mount a cytotoxic T-cell (CTL) response against telomerase-expressing tumor cells, which may result in tumor cell death. Telomerase prolongs the functional lifespan of cells via the restoration and maintenance of telomere length. Abnormally activated in tumorigenesis, telomerase is expressed in the majority of human cancer cells, but its expression is low or non-existent in normal cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C120118</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02960594</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:34230114</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5171</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/409</obo:IAO_0000233>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5171</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>synthetic hTERT DNA vaccine INO-1400</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007046 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007046</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of E-PRA and E-PSM, two synthetic peptide analogs of PRAME (PReferential Antigen MElanoma) and PSMA (Prostate Specific Membrane Antigen), with potential immunostimulating activity. Upon direct administration into lymph nodes, synthetic peptides E-PRA and E-PSM vaccine may sitmulate a cytotoxic T-lymphocyte (CTL) response against PRAME- and PSMA-expressing tumor cells. PRAME and PSMA are tumor-associated antigens upregulated and expressed on the cell surfaces of certain tumor cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C67098</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00423254</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:21760528</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5496</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/412</obo:IAO_0000233>
        <obo:OGG_0000000006>6277</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5496</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: S100A6</rdfs:comment>
        <rdfs:label>synthetic peptides E-PRA and E-PSM vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007047 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007047</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide-based cancer vaccine, containing amino acid residues 27 through 35 of T cell receptor gamma alternate reading frame protein (TARP), with potential immunostimulatory and antineoplastic activities. Upon administration, TARP 27-35 peptide vaccine may stimulate a host cytotoxic T-cell (CTL) response against TARP-expressing tumor cells, resulting in tumor cell cytotoxicity. The nuclear protein TARP is commonly expressed on prostate and breast cancer cells and is highly immunogenic.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C85462</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00972309</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27622067</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5448</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/413</obo:IAO_0000233>
        <obo:OGG_0000000006>445347</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5448</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TARP</rdfs:comment>
        <rdfs:label>TARP 27-35 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007048 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007048</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide-based cancer vaccine, consisting of amino acid residues 29 through 37 of T cell receptor gamma alternate reading frame protein (TARP) with a leucine-to-valine substitution at position 9, with potential immunostimulatory and antineoplastic activities. Upon administration, TARP 29-37-9V peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against TARP-expressing tumor cells, which may result in decreased tumor cell proliferation. The leucine-to-valine substitution at position 9 of this peptide improves its immunogenicity. The nuclear protein TARP is commonly expressed on prostate and breast cancer cells and is highly immunogenic.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C85463</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02362464</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27622067</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5242</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/414</obo:IAO_0000233>
        <obo:OGG_0000000006>445347</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5242</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TARP</rdfs:comment>
        <rdfs:label>TARP 29-37-9V peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007049">
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007049</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant vector encoding the tumor-associated carcinoembryonic antigen (CEA) that is‚Äö√†√∂‚àö¬ßcontaminated‚Äö√†√∂‚àö¬ßwith bovine viral diarrhea virus (BVDV). The carcinoembryonic antigen (CEA) is a prevalent tumor marker expressed by a number of different cancers such as colorectal, breast, lung and ovarian carcinomas; vaccination with vaccinia virus genetically engineered to express‚Äö√†√∂‚àö¬ßCEA‚Äö√†√∂‚àö¬ßmay generate antitumoral T-cell responses.‚Äö√†√∂‚àö¬ßBVDV‚Äö√†√∂‚àö¬ßis an RNA pestivirus that may contaminate vaccines due to its presence in fetal calf serum used as a growth supplement in the tissue culture of mammalian cells used in vaccine production.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29476</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:35380920</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5295</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/415</obo:IAO_0000233>
        <obo:OGG_0000000006>4153</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5295</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MBL2</rdfs:comment>
        <rdfs:label>TBC-CEA-Contaminated W/ BVDV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007050">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007050</metadata:prefixIRI>
        <obo:IAO_0000115>A lipid-based multi-peptide cancer vaccine targeted against multiple cancers with immunopotentiating activity. Therapeutic breast/ovarian/prostate peptide cancer vaccine DPX-0907 is a lyophilized liposomal proprietary preparation comprised of 7 tumor-specific HLA-A2-restricted epitopes (TAAs): topoisomerase II alpha, B-cell receptor-associated protein 31 (CDM protein), TNF-alpha-converting enzyme (TACE/ADAM17), Abelson homolog 2 (Abl2), gamma catenin (Junction plakoglobin), epithelial discoidin domain receptor 1 (EDDR1) and integrin beta 8 subunit. Upon vaccination, the lyophilized antigen/adjuvant/liposome complex is re-suspended in Montanide 1SA51 VG to create a depot effect, thereby presenting the TAAs to the immune system for a prolonged period of time. This may stimulate a potent cytotoxic T-lymphocyte (CTL) immune response against cancer cells that express these 7 TAAs and share epitopes with the vaccine epitope peptides, resulting in tumor cell lysis. The 7 TAAs are overexpressed on the surface of breast/ovarian and prostate cancer cells and play an important role in tumor cell growth and survival.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C91077</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01095848</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:22862954</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5458</obo:IAO_0000119>
        <obo:OGG_0000000006>10134</obo:OGG_0000000006>
        <obo:OGG_0000000006>27</obo:OGG_0000000006>
        <obo:OGG_0000000006>3696</obo:OGG_0000000006>
        <obo:OGG_0000000006>3728</obo:OGG_0000000006>
        <obo:OGG_0000000006>6868</obo:OGG_0000000006>
        <obo:OGG_0000000006>7153</obo:OGG_0000000006>
        <obo:OGG_0000000006>780</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5458</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ABL2</rdfs:comment>
        <rdfs:comment>Gene name: ADAM17</rdfs:comment>
        <rdfs:comment>Gene name: BCAP31</rdfs:comment>
        <rdfs:comment>Gene name: DDR1</rdfs:comment>
        <rdfs:comment>Gene name: IGTB8</rdfs:comment>
        <rdfs:comment>Gene name: JUP</rdfs:comment>
        <rdfs:comment>Gene name: TOP2A</rdfs:comment>
        <rdfs:label>therapeutic Breast/Ovarian/Prostate peptide cancer vaccine DPX-0907</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007051 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007051</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing URLC10 (up-regulated lung cancer 10) epitopes with potential immunostimulatory and antineoplastic activities. Upon administration, URL peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against URLC10-expressing tumor cells. Up-regulated in lung and esophageal cancers, the function of URLC10 is unknown.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C74087</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00624182</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:29568993</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5115</obo:IAO_0000119>
        <obo:OGG_0000000006>54742</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4606"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5115</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: LY6K</rdfs:comment>
        <rdfs:label>URLC10 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007052 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007052</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing five peptide epitopes with potential immunostimulatory and antitumor activity. Peptide epitopes in this vaccine are derived from: URLC10 (up-regulated lung cancer 10), TTK (TTK protein kinase), KOC1 (IGF II mRNA Binding Protein 3) and VEGFRs (vascular endothelial growth factor receptors) 1 and 2. Upon administration, URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, TTK, KCO1, VEGFR 1 and 2 peptides, resulting in cell lysis and decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C74088</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00632333</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:24708624</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5001</obo:IAO_0000119>
        <obo:OGG_0000000006>10643</obo:OGG_0000000006>
        <obo:OGG_0000000006>54742</obo:OGG_0000000006>
        <obo:OGG_0000000006>7422</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5001</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IGF2BP3</rdfs:comment>
        <rdfs:comment>Gene name: LY6K</rdfs:comment>
        <rdfs:comment>Gene name: VEGFA</rdfs:comment>
        <rdfs:label>URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007053 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007053">
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007053</metadata:prefixIRI>
        <obo:IAO_0000115>A highly tumor-selective vaccinia virus (vv) with an engineered double deletion (DD) of the thymidine kinase (tk) and vaccinia growth factor genes and additions of both a cytosine deaminase (CD) gene and a somatostatin receptor (SR) gene with potential oncolytic viral activity. The tk and vaccinia growth factor gene deletions in intratumorally administered vaccinia virus (vvDD-CDSR) help to restrict its replication and cytolytic activity to tumor cells with large nucleotide pools and tumor cells with activation of the EGFR-Ras pathway. Addition of the CD gene to the viral genome allows control of oncolytic viral infection through the administration of the prodrug 5-fluorocytosine (5-FC), converted by CD to the antimetabolite 5-fluorouracil (5-FU) in cells infected with this agent. Addition of the SR gene allows anatomical localization of vaccinia virus (vvDD-CDSR) through the use of octreotide scintigraphy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C74089</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00574977</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27203445</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5296</obo:IAO_0000119>
        <obo:OGG_0000000006>45091589</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5296</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: cdsR</rdfs:comment>
        <rdfs:label>Vaccinia virus DD-CDSR vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007054">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007054</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of two plasmids encoding the human cytomegalovirus (CMV) tegument phosphoprotein 65 (pp65), a major internal matrix protein, and glycoprotein B (gB), an important CMV component responsible for attachment and entry into cells, with immunostimulatory properties. Vaccination with VCL-CB01 may stimulate the host immune system to mount cellular and humoral immune responses against CMV positive cells, resulting in cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C61327</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00285259</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:22237175</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5390</obo:IAO_0000119>
        <obo:OGG_0000000006>3077579</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5390</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: UL83</rdfs:comment>
        <rdfs:label>VCL-CB01 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007055">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007055</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated bacteria injectable vaccine used to prevent typhoid, which is caused by Salmonella typhi.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C97127</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT03294564</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7487253</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5322</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5322</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vi capsular polysaccharide typhoid vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007056 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007056">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <obo:IAO_0000115>A synthetic peptide vaccine consisting of a HLA-DR15-restricted human Wilms&apos; Tumor protein-1 (WT1) peptide comprised of amino acids 124 through 138, a HLA class II-restricted WT1 peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 124-138 peptide may stimulate a CD4-positive helper T-lymphocyte-mediated immune response against WT1 expressing cells. Activated helper T-cells stimulate dendritic cells, and activate the proliferation of other T-lymphoctes and B-lymphocytes. This causes tumor cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing tumor cells. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C104738</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16220325</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5430</obo:IAO_0000119>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
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        <obo:VO_0001818>5430</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>WT1 124-138 peptide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007057 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007057</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide vaccine consisting of the amino acids 126 through 134 of the human Wilms&apos; Tumor protein-1 (WT1) with potential antitumor activity. WT1, a tumor associated antigen, is overexpressed in most types of leukemia and in a variety of solid cancers. Vaccination with WT1 126-134 peptide vaccine may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
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        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01842139</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26492414</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5089</obo:IAO_0000119>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
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        <obo:VO_0001818>5089</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>WT1 126-134 peptide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007058 -->

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        <obo:IAO_0000115>A synthetic peptide vaccine consisting of a HLA-A24-restricted human Wilms&apos; Tumor protein-1 (WT1) peptide comprised of amino acids 235 through 243, a MHC class I-restricted peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 235-243 peptide may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
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        <obo:IAO_0000119>PMID:23225417</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5029</obo:IAO_0000119>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>WT1 235-243 peptide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007059 -->

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        <obo:IAO_0000115>A synthetic peptide vaccine consisting of a HLA-DRw53-restricted human Wilms&apos; Tumor protein-1 (WT1) peptide comprised of amino acids 247 through 261, a HLA class II-restricted WT1 peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 247-261 peptide may stimulate a CD4-positive helper T-lymphocyte-mediated immune response against WT1 expressing cells. Activated helper T-cells stimulate dendritic cells, and activate the proliferation of other T-lymphoctes and B-lymphocytes. This causes tumor cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing tumor cells. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
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        <obo:IAO_0000119>PMID:16220325</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5468</obo:IAO_0000119>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5468</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>WT1 247-261 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007060 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007060</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of the DNA plasmid pNGVL4a-A encoding calreticulin (CRT) linked to a detox form of human papillomavirus (HPV) type 16 E7 antigen, with potential immunomodulating and antineoplastic activities. Upon administration, this vaccine may generate a potent cytotoxic T-lymphocyte (CTL) response against E7-expressing tumor cells, resulting in tumor cell death. For E7(detox), the amino acids in E7 at positions 24 (cysteine to glycine) and 26 (glutamic acid to glycine) were substituted. CRT, a 46 kDa protein located in the lumen of the cell&apos;s endoplasmic reticulum (ER), may potentiate MHC class I presentation of HPV-16 E7 to E7-specific CD8-positive T cells. In addition, pNGVL4a-A contains two short immunostimulatory DNA sequences (ISS) in the noncoding region, which may elicit the production of IFN- and IL-12 in transfected keratinocytes and dermal antigen presenting cells (APCs), resulting in a potent T helper cell type 1 response.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C88289</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00988559</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26616223</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5011</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/123</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5011</obo:VO_0001818>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HPV16 E7</rdfs:comment>
        <rdfs:label>pNGVL4a-CRT/E7(detox) DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007061 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007061</metadata:prefixIRI>
        <obo:IAO_0000115>An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock protein 70 (HSP70). Upon administration, this vaccine may generate potent cytotoxic CD8(+) T-cell responses against E7-expressing tumor cells, resulting in tumor cell death.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C48418</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00121173</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:30296681</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5069</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/124</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5069</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HPV16 E7</rdfs:comment>
        <rdfs:label>pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007062 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007062</metadata:prefixIRI>
        <obo:IAO_0000115>A non-infectious recombinant, quadrivalent vaccine prepared from the highly purified virus-like particles (VLPs) of the major capsid (L1) protein of human papillomavirus (HPV) Types 6, 11, 16, and 18 with immunoprophylactic activity. The immunoprohylactic efficacy of L1 VLP vaccines, such as recombinant human papillomavirus quadrivalent vaccine, appear to be mediated by the development of humoral immune responses. HPV Types 16 and 18 account for approximately 70% of cervical cancers and HPV Types 6 and 11 account for approximately 90% of genital warts.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C61087</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00411749</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:35997582</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5406</obo:IAO_0000119>
        <obo:OGG_0000000006>25479185</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5406</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: L1</rdfs:comment>
        <rdfs:label>Quadrivalent Human Papillomavirus (types 6, 11, 16, 18) Recombinant Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007063 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007063</metadata:prefixIRI>
        <obo:IAO_0000115>A non-infectious, recombinant, nonavalent vaccine prepared from highly purified virus-like particles (VLPs) comprised of the major capsid (L1) proteins from human papillomavirus (HPV) types 6, 11, 16, 18, 31, 33, 45, 52, and 58, with active immunizing activity. Upon administration, the recombinant HPV nonavalent vaccine activates the immune system to produce antibodies against the 9 HPV types. This protects against HPV infection and HPV-related cancers. Altogether, HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58 account for the majority of the HPV types that cause cervical, vulvar, vaginal and anal cancers.‚Äö√†√∂‚àö¬ß</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C119664</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26772631</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5342</obo:IAO_0000119>
        <obo:OGG_0000000006>25479185</obo:OGG_0000000006>
        <obo:OGG_0000000006>7162</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5342</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: L1</rdfs:comment>
        <rdfs:comment>Gene name: TPBG</rdfs:comment>
        <rdfs:label>Recombinant Human Papillomavirus Nonavalent Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007064">
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007064</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a modified, replication-defective, vaccinia virus Ankara (MVA) strain encoding the tumor-associated antigens (TAAs) human papillomavirus type 16 (HPV16) subtypes E6 and E7, and human interleukin-2 (IL-2), with potential immunostimulating and antineoplastic activities. Vaccination with MVA-HPV16E6/E7-IL2 vaccine TG4001 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing HPV16 E6 and E7, resulting in tumor cell lysis. Expression of IL-2 augments the specific CTL response against HPV16 E6- and E7-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C88326</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01022346</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5208</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/340</obo:IAO_0000233>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5208</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>Recombinant Vaccinia Viral Vector RO5217790 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007065 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007065">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007065</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic peptide vaccine consisting of thirteen synthetic long peptides (SLPs), which are 25-35 amino acids in size, derived from the human papillomavirus (HPV) type 16 oncoproteins E6 and E7, with potential immunostimulating and antitumor activities. Upon administration, synthetic long E6/E7 peptides vaccine HPV-01 is taken up and degraded into small pieces by dendritic cells. The processed viral epitopes are presented by dendritic cells, which may stimulate the host immune system to mount both cytotoxic T-cell lymphocyte (CTL) and helper T cell responses against HPV E6/E7-expressing tumor cells. This results in the destruction of tumor cells and leads to decreased tumor growth. The E6 and E7 oncoproteins are implicated in the tumorigenesis in a variety of cancers. The SLPs allow for optimal presentation by antigen-presenting cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C111037</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02128126</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5186</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/410</obo:IAO_0000233>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5186</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>Synthetic Long E6/E7 Peptides Vaccine HPV-01</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007066 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007066</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers. E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2811</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00493545</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16691066</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5542</obo:IAO_0000119>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:OGG_0000000006>3329</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5542</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:comment>Gene name: HSPD1</rdfs:comment>
        <rdfs:label>Verpasep Caltespen Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007067 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007067</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine used for cancer immunotherapy also known as Ras(cis 12)-Vaccinia Vaccine, RASVAC-C is based on a mutant peptide epitope of the Ras oncoprotein at codon 12 that induces recognition and induction of tumor-specific, cell-mediated immune responses. Ras is an intracellular GTP-binding protein involved in signal transduction and regulation of proliferation and differentiation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29401</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00019591</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5504</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/190</obo:IAO_0000233>
        <obo:OGG_0000000006>3845</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5504</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KRAS</rdfs:comment>
        <rdfs:label>RASVAC-C Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007068 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007068</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine used for cancer immunotherapy also known as Ras(val 12)-Vaccinia Vaccine, RASVAC-V is based on a mutant peptide epitope of the Ras oncoprotein at codon 12 (valine instead of glycine) that induces recognition and induction of tumor-specific, cell-mediated immune responses. Ras is an intracellular GTP-binding protein involved in signal transduction and regulation of proliferation and differentiation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29402</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00019591</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5497</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/191</obo:IAO_0000233>
        <obo:OGG_0000000006>3845</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5497</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KRAS</rdfs:comment>
        <rdfs:label>RASVAC-V Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007069 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007069</metadata:prefixIRI>
        <obo:IAO_0000115>A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity. Recombinant adenovirus-p53 SCH-58500 delivers p53 into tumor cells, which may result in p53-mediated cell cycle arrest and apoptosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2423</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00002960</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16082381</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5470</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/325</obo:IAO_0000233>
        <obo:OGG_0000000006>4771</obo:OGG_0000000006>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5470</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NF2</rdfs:comment>
        <rdfs:comment>Gene name: TP53 (P53)</rdfs:comment>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>Recombinant Adenovirus-p53 SCH-58500 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007070 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007070</metadata:prefixIRI>
        <obo:IAO_0000115>An immunocytokine consisting of human pro-inflammatory cytokine tumor necrosis factor alpha (TNFalpha) fused to a human single-chain variable fragment (scFv) directed against the extra-domain B (ED-B) of fibronectin (L19), with potential immunopotentiating and antineoplastic activities. Upon adinistration, the L19 moiety of onfekafusp alfa binds to the ED-B domain of fibronectin on tumor cells in the tumor neovasculature. In turn, the TNFalpha moiety may locally induce an immune response against ED-B fibronectin-expressing tumor cells and may specifically decrease the proliferation of ED-B-expressing tumor cells. ED-B is predominantly expressed during angiogenesis and tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C166939</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01253837</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12810649</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5219</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/336</obo:IAO_0000233>
        <obo:OGG_0000000006>100136034</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5219</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: tnf-alpha</rdfs:comment>
        <rdfs:label>Recombinant Human Fusion Protein L19TNFalpha Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007071 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007071</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing multiple peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this vaccine are derived from, URLC10 (up-regulated lung cancer 10), CDCA1 (cell division cycle-associated protein 1), KOC1 (IGF II mRNA Binding Protein 3). Upon administration, URLC10-CDCA1-KOC1 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, CDCA1, KCO1 peptides, resulting in cell lysis and decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C95212</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00681577</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27720136</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5350</obo:IAO_0000119>
        <obo:OGG_0000000006>10643</obo:OGG_0000000006>
        <obo:OGG_0000000006>54742</obo:OGG_0000000006>
        <obo:OGG_0000000006>83540</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10534"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5350</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IGF2BP3</rdfs:comment>
        <rdfs:comment>Gene name: LY6K</rdfs:comment>
        <rdfs:comment>Gene name: NUF2</rdfs:comment>
        <rdfs:label>URLC10-CDCA1-KOC1 Multipeptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007072 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007072</metadata:prefixIRI>
        <obo:IAO_0000115>A fusion DNA vaccine containing the first domain of fragment C (FrC) of tetanus toxin (TT865-1120) (p.DOM) fused to the human Wilms&apos; Tumor gene-1 (WT1)-derived MHC class I-binding epitope WT1.126, with potential antitumor activity. Upon vaccination with p.DOM-WT1-126 DNA and subsequent electroporation, this vaccine may induce a WT1 epitope-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing cancer cells. WT1, a tumor associated antigen, is overexpressed in most types of leukemia and in a variety of solid cancers. The FrC of tetanus toxin contains the MHC II-binding sequence, p30, which induces T-helper cell activation for long-lasting immunity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C96738</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01334060</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27099895</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5165</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/69</obo:IAO_0000233>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5165</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>p.DOM-WT1-126 DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007073">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007073</metadata:prefixIRI>
        <obo:IAO_0000115>A fusion DNA vaccine containing the first domain of fragment C (FrC) of tetanus toxin (TT865-1120) (p.DOM) fused to the human Wilms&apos; Tumor gene-1 (WT1)-derived MHC class I-binding epitope WT1.37, with potential antitumor activity. Upon vaccination with p.DOM-WT1-37 DNA and subsequent electroporation, this vaccine may induce a WT1 epitope-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing cancer cells. WT1, a tumor associated antigen, is overexpressed in most types of leukemia and in a variety of solid cancers. The FrC of tetanus toxin contains the MHC II-binding sequence, p30, which induces T-helper cell activation for long-lasting immunity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C96737</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01334060</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27099895</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5471</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/61</obo:IAO_0000233>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/62</obo:IAO_0000233>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5471</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>p.DOM-WT1-37 DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007074 -->

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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007074</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing PR1, a 9 amino-acid human leukocyte antigen (HLA)-A2 restricted peptide derived from proteinase 3, with potential immunotherapeutic activity. Vaccination with PR1 leukemia peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing proteinase 3, resulting in tumor cell lysis. Often overexpressed in leukemic cells, proteinase 3 is a serine proteinase that activates progelatinase A and is involved in angiogenesis and metastasis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2235</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00004918</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27654852</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5140</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/139</obo:IAO_0000233>
        <obo:OGG_0000000006>140738</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5140</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TMEM37</rdfs:comment>
        <rdfs:label>PR1 Leukemia Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007075">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007075</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine made of cancer cells, parts of cancer cells, or pure tumor antigens (substances isolated from tumor cells). A tumor antigen vaccine may stimulate the body&apos;s immune system to find and kill cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2341</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00100971</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:30348199</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5387</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5387</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Tumor Cell Derivative Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007076</metadata:prefixIRI>
        <obo:IAO_0000115>A leukemia cancer vaccine comprised of a peptide derived from Wilms tumor gene 1 (WT1) protein, with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration, WT1 peptide vaccine OCV-501 may stimulate a CD4-positive helper T-lymphocyte-mediated immune response against WT1 expressing cells. WT1 protein, a zinc finger DNA-binding protein, is overexpressed in leukemic cells and in some solid tumors.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C106257</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01961882</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:28321480</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5330</obo:IAO_0000119>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5330</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>WT1 Peptide Vaccine OCV-501</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007077 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007077</metadata:prefixIRI>
        <obo:IAO_0000115>An immunotherapeutic consisting of the recombinant fusion protein WT1-A10 combined with the adjuvant ASO1B with potential immunostimulating and antineoplastic activities. Upon administration, WT1-A10/AS01B immunotherapeutic GSK2130579AWT1 may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1-expressing tumor cells, resulting in cell lysis and the inhibition of cellular proliferation. The tumor-associated antigen WT1 (Wilms tumor protein-1) is overexpressed in most types of leukemia and in a variety of solid cancers. WT1-A10 is a 292 amino acid recombinant fusion protein consisting of a 12-mer truncated tat sequence (leader sequence) and amino acids number 2-281 of the WT1 sequence; ASO1B consists of a combination of the adjuvants monophosporyl lipd A (MPL) and Q21.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C78865</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00725283</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16117707</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5354</obo:IAO_0000119>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5354</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>WT1-A10/AS01B Immunotherapeutic GSK2130579A Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007078 -->

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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007078</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant vaccinia virus encoding carcinoembryonic antigen (CEA). CEA is overexpressed in several cancer cell types, including gastrointestinal, breast, and non-small cell lung cancers. Attenuated vaccinia virus is a highly effective immunizing agent that evokes both humoral and cell-mediated responses. Vaccination with this agent may evoke a cytotoxic immune response to CEA-expressing cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2809</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00081848</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7629885</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5401</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/341</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5401</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:label>Recombinant Vaccinia-CEA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007079 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007079">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007079</metadata:prefixIRI>
        <obo:IAO_0000115>Human mesenchymal stem cells (MSCs) harvested from bone marrow of healthy adult donors and expanded ex vivo, with potential immunosuppressive activity. Remestemcel-L cells are hypo-immunogenic due to lack of major histocompatibility II (MHC II) molecule expression, eliciting little, if any, host immune response upon intravenous infusion. Infusion of allogeneic MSCs may result in: a) increased production of anti-inflammatory cytokines, such as interleukin-10, prostaglandin E, and hepatocyte growth factor; b) decreased mononuclear phagocyte expression of indoleamine 2,3,-dioxygenase, which catabolizes L-tryptophan into its pro-inflammatory metabolites; and c) modulated dendritic cell (DC)maturation and disrupted activities of natural killer (NK) cells and CD8+ and CD4+ T cells. In addition, pluripotent MSCs, upon administration, may be recruited to damaged tissue sites, differentiating along specific lineages when stimulated.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C67082</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:32018062</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4993</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/353</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4993</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Remestemcel-L Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007080</metadata:prefixIRI>
        <obo:IAO_0000115>A replication-competent oncolytic, telomerase-specific adenovirus serotype 5 (Ad5), with potential antineoplastic activity. OBP-301 contains the human telomerase reverse transcriptase (hTERT) gene promoter sequence that drives the expression of the E1A and E1B genes, and is linked to an internal ribosomal entry site (IRES). Upon administration, OBP-301 selectively infects and replicates in cancer cells that are expressing telomerase, which causes cell lysis. This adenovirus does not infect or replicate in normal, healthy cells. OBP-301 may also potentially be used as a chemosensitizer. hTERT, which encodes for the catalytic protein subunit of telomerase, is overexpressed in a variety of cancer cell types but not in normal, healthy cells. The insertion of an IRES further improves selectivity towards telomerase-expressing cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C119617</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02293850</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27673332</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5072</obo:IAO_0000119>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5072</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>Telomerase-specific Type 5 Adenovirus OBP-301 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007081 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007081">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007081</metadata:prefixIRI>
        <obo:IAO_0000115>A proprietary cancer DNA vaccine that contains multiple natural and modified epitopes derived from the four tumor associated antigens, CEA, HER2/neu, p53, and MAGE 2/3. OSE 2101 also includes CAP1-6D, a heteroclitic CEA analog, and PADRE, a proprietary universal T-cell epitope that serves to enhance the immunogenicity of the epitopes. This agent has been shown to elicit cytotoxic T-lymphocyte responses against tumor cells expressing these multiple epitopes.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C26645</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02654587</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:18382135</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5528</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/72</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:OGG_0000000006>4101</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5528</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA2</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:comment>Gene name: TP53</rdfs:comment>
        <rdfs:label>EP-2101 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007082 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007082">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007082</metadata:prefixIRI>
        <obo:IAO_0000115>A tumor-specific peptide encoded by patient-specific mutant p53 oncogene with potential immunostimulatory properties. The peptide (LPTGQDL) contains a frame shift mutation at amino acid position 134. It was used to pulse dendritic cells, which are then used in the adoptive immunotherapy setting and may stimulate the host immune system to mount a specific cytotoxic T lymphocyte response against tumor cells expressing the p35 mutation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C38121</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00049218</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:29301826</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5272</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/125</obo:IAO_0000233>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/193</obo:IAO_0000233>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5272</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TP53</rdfs:comment>
        <rdfs:label>PR-151 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007083 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007083</metadata:prefixIRI>
        <obo:IAO_0000115>An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional structure of N-glycolyl ceramides of mono-sialyl lactose, the antigenic target of P3. As a result, this anti-idiotype antibody may stimulate the host immune system to elicit humoral and cellular immune responses against tumor cells expressing NeuGc-GM3 gangliosides, which are expressed in a wide variety of tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C95024</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01598454</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26903265</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5201</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/188</obo:IAO_0000233>
        <obo:OGG_0000000006>3265</obo:OGG_0000000006>
        <obo:OGG_0000000006>3845</obo:OGG_0000000006>
        <obo:OGG_0000000006>4893</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5201</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HRAS</rdfs:comment>
        <rdfs:comment>Gene name: KRAS</rdfs:comment>
        <rdfs:comment>Gene name: NRAS</rdfs:comment>
        <rdfs:label>Racotumomab Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007084 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007084</metadata:prefixIRI>
        <obo:IAO_0000115>A replication-defective adenovirus containing a gene that encodes the human protein L523S with potential antineoplastic activity. Upon administration, recombinant adenovirus-L523S vaccine expresses L523S, which may stimulate antibody and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing L523S. L523S is an RNA-binding protein that belongs to the KOC (K homology domain containing protein over-expressed in cancer) family of proteins. As an oncofetal protein, L523S is normally expressed in early embryonic tissues and certain normal adult tissues such as colon, fallopian tube, gall bladder, and ovary tissues but may be overexpressed in squamous cell cancers of the lung.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C49289</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00062907</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16581300</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5074</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/323</obo:IAO_0000233>
        <obo:OGG_0000000006>10643</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5074</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IGF2BP3</rdfs:comment>
        <rdfs:label>Recombinant Adenovirus-L523S Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007085 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007085">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007085</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA encoding human L523S, an RNA-binding protein that belongs to the KOC (K homology domain containing protein overexpressed in cancer) family, with potential antineoplastic activity. Vaccination with L523S DNA may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells that express the L523S protein. As an oncofetal protein, L523S is normally expressed in early embryonic tissue, but is overexpressed in certain cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C49290</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00062907</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12750279</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5156</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/327</obo:IAO_0000233>
        <obo:OGG_0000000006>10643</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5156</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IGF2BP3</rdfs:comment>
        <rdfs:label>Recombinant DNA-L523S Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007086 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007086">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007086</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine preparation, containing recombinant human epidermal growth factor (rEGF) linked to the Neisseria meningitidis-derived recombinant immunogenic carrier protein P64k (rP64k) and mixed with the immunoadjuvant Montanide ISA 51, with potential active immunotherapy activity. Recombinant human EGF-rP64K/Montanide ISA 51 vaccine may trigger a humoral immune response against vaccine rEGF and rP64K and, so, against endogenous EGF. Antibody-mediated inhibition of endogenous EGF binding to its receptor, epithelial growth factor receptor (EGFR), may result in the inhibition of tumor cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C70674</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00516685</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:29661145</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5190</obo:IAO_0000119>
        <obo:OGG_0000000006>25003478</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
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        <obo:VO_0001818>5190</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: LV28_RS26095 transcriptional regulator RegF</rdfs:comment>
        <rdfs:label>Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007087 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007087</metadata:prefixIRI>
        <obo:IAO_0000115>An allogeneic lung cancer vaccine with potential immunostimulating and antineoplastic activities. Derived from allogeneic lung tumor cells, tergenpumatucel-L is engineered to express the murine alpha-1,3-galactosyltransferase (GalT), an enzyme humans lack. GalT catalyzes the expression of foreign alpha-1,3-galactosyl (alpha-gal) carbohydrate epitopes in glycoproteins and in glycolipids on the cell membranes of the allogeneic lung tumor cells present in the vaccine, essentially producing a &apos;xenograft&apos;. The hyperacute rejection involves pre-existing human anti-alpha-gal antibodies that bind the foreign alpha-gal epitopes expressed by the vaccine tumor cell xenograft, resulting in complement-mediated cytotoxicity (CMC) and antibody-dependent cell-mediated cytotoxicity (ADCC) towards endogenous lung tumor cells with unmodified carbohydrate epitopes.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C66985</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02460367</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:28238782</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5527</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5527</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Tergenpumatucel-L Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007088 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007088</metadata:prefixIRI>
        <obo:IAO_0000115>A proprietary, allogeneic tumor cell vaccine expressing a recombinant secretory form of the heat shock protein gp96 fusion (gp96-Ig) with potential antineoplastic activity. Upon administration of viagenpumatucel-L, the irradiated live tumor cells continuously secrete gp96-Ig along with its chaperoned tumor associated antigens (TAAs) into the blood stream, thereby activating antigen presenting cells, natural killer cells and priming potent cytotoxic T lymphocytes (CTLs) to respond against TAAs on the endogenous tumor cells. Furthermore, this vaccine may induce long-lived memory T cells that could fight recurring cancer cells. gp96-Ig is constructed by replacing the KDEL retention sequence of gp96, normally an endoplasmatic reticulum-resident chaperone peptide, with the Fc portion of mouse and human IgG1.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C61073</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02439450</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27364122</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5513</obo:IAO_0000119>
        <obo:OGG_0000000006>7184</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5513</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HSP90B1</rdfs:comment>
        <rdfs:label>Viagenpumatucel-L Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007089 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007089</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a mixture of a murine lymphoma-derived idiotype and interleukin-2 (IL-2) encapsulated in dimyristoylphosphatidylcholine liposomes. The use of a liposomal carrier confers immunogenicity to the naturally non-immunogenic idiotype.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2783</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5541</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/74</obo:IAO_0000233>
        <obo:OGG_0000000006>107653060</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5541</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IL12</rdfs:comment>
        <rdfs:label>Oncovax-ID/IL-2 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007090 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007090">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007090</metadata:prefixIRI>
        <obo:IAO_0000115>A lipid depot-based therapeutic cancer vaccine composed of survivin epitopes, a universal T Helper peptide and a polynucleotide adjuvant encapsulated in liposomes and then formulated in the hydrophobic carrier Montanide ISA51 VG, with potential immunopotentiating and antineoplastic activities. Upon injection of the maveropepimut-S, a depot is created at the injection site from which the antigens and adjuvant are released. This vaccine may elicit a long lasting cellular response against survivin-expressing cancers, resulting in a decrease in tumor cell proliferation and an induction of tumor cell death. Survivin, a member of the inhibitor of apoptosis (IAP) family expressed during embryonic development, is upregulated in a variety of human cancers while absent in most normal adult cells; its expression in tumors is associated with a more aggressive phenotype, decreased survival, and increased resistance to chemotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C97951</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02323230</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26405584</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5371</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/364</obo:IAO_0000233>
        <obo:OGG_0000000006>373110</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5371</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Survivin</rdfs:comment>
        <rdfs:label>Survivin Antigen Vaccine DPX-Survivac</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007091 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007091">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007091</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of lymphoma-specific immunoglobulin that is not conjugated to a carrier molecule. Vaccination with unconjugated lymphoma Ig Id may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against lymphoma cells, resulting in decreased tumor growth.‚Äö√†√∂‚àö¬ß</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2821</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:18715553</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5046</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5046</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Unconjugated Lymphoma Ig Id Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007092 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007092">
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007092</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide cancer vaccine consisting of peptides derived from the melanoma antigen NA-17, the human leukocyte antigen HLA-A2-restricted human melanoma antigen 3 (MAGE-3.A2) and the cancer-testis antigen (NY-ESO-1), with potential immunostimulating and antineoplastic activities. Upon administration, the NA-17/MAGE-3.A2/NY-ESO-1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing NA-17, MAGE-3.A2 and NY-ESO-1, resulting in tumor cell lysis. The tumor-associated antigens (TAAs) NA-17, MAGE-3.A2 and NY-ESO-1 are overexpressed in a variety of cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C96042</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01308294</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:25941588</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5305</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/48</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5305</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:label>NA-17/MAGE-3.A2/NY-ESO-1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007093">
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007093</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide cancer vaccine comprised of human leukocyte antigen HLA-A2-restricted peptide derived from a metastatic melanoma cell line of patient NA17, with potential immunomodulating and antineoplastic activity. NA17. A2 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumors that express this antigen, which may result in a reduction in tumor size. This NA17 specific antigen, encoded by an intron sequence of N-acetylglucosaminyltransferase V (GnT-V) gene, is expressed in about 50% of melanomas.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2680</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01307618</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16133111</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5323</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/49</obo:IAO_0000233>
        <obo:OGG_0000000006>107653060</obo:OGG_0000000006>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5323</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IL12</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: PMEL</rdfs:comment>
        <rdfs:label>NA17.A2 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007094 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007094">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007094</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with a peptide derived from the tumor associated antigen human cancer-testis antigen NY-ESO-1 (NY-ESO-1(157-165)), with potential immunostimulatory and antineoplastic activities. Upon administration, the NY-ESO-1(157-165) peptide-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount both an anti-tumoral cytotoxic T-lymphocyte (CTL) and an antibody-mediated immune response against NY-ESO-1-expressing tumor cells, which may result in tumor cell lysis. NY-ESO-1 is expressed both in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C114380</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00313508</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16311731</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5100</obo:IAO_0000119>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5100</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: PMEL</rdfs:comment>
        <rdfs:comment>Gene name: TYR</rdfs:comment>
        <rdfs:label>NY-ESO-1(157-165) peptide-pulsed autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007095 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007095">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007095</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of dendritic cells (DC) pulsed with peptides derived from the tumor-associated antigens human cancer/testis antigen NY-ESO-1 and melanoma antigen recognized by T-cells (MART-1/Melan-A), with potential immunostimulatory and antineoplastic activities. Upon administration, the NY-ESO-1/MART-1 peptide-pulsed DC vaccine may stimulate the immune system to mount an anti-tumor cytotoxic T-lymphocyte (CTL) response against NY-ESO-1/MART-1-expressing tumor cells, which may result in tumor cell lysis. NY-ESO-1 is expressed both in normal testes and on the surfaces of various tumor cells. MART-1 is expressed by melanoma cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C120129</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00798629</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16311731</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5366</obo:IAO_0000119>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5366</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:label>NY-ESO-1/MART-1 peptide-pulsed dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007096">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007096</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of PEP-3, a synthetic peptide encompassing a tumor-specific mutated segment of the epidermal growth factor receptor type vIII (EGFRvIII), conjugated to the naturally-occurring immunoadjuvant keyhole limpet hemocyanin (KLH) with potential immunostimulating and antineoplastic activities. Upon administration, PEP-3-KLH conjugate vaccine may induce a cytotoxic immune response against tumor cells that overexpress EGFRvIII; this antitumoral immune response may involve antibody-dependent cellular cytotoxicity (ADCC).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C74070</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00626015</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:14519652</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5480</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/117</obo:IAO_0000233>
        <obo:OGG_0000000006>1956</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5480</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EGFR</rdfs:comment>
        <rdfs:label>PEP-3-KLH conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007097">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007097</metadata:prefixIRI>
        <obo:IAO_0000115>A whole cell vaccine derived from a distinct subset of dendritic cells (DCs) with a plasma cell-like morphology that exhibits immunomodulating activity. Plasmacytoid dendritic cells (pDCs) express a characteristic set of surface markers, such as CD123 (interleukin-3 receptor alpha chain), BDCA-2 (blood dendritic cell antigen 2; CD303) and BDCA-4 (CD304), as well as intracellular toll-like receptors 7 and 9. Upon stimulation, the activated pDCs produce substantial amounts of interferon (IFN) alpha, and to a lesser degree IFN-beta, as well as other cytokines and chemokines, such as tumor necrosis factor alpha and interleukins 1, 6 and 8. In addition, these pDCs, directly or indirectly stimulate T-cells, B-cells and natural killer cells. This may potentially lead to increased immunity against tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C103192</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01690377</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:30049538</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5006</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/121</obo:IAO_0000233>
        <obo:OGG_0000000006>170482</obo:OGG_0000000006>
        <obo:OGG_0000000006>3598</obo:OGG_0000000006>
        <obo:OGG_0000000006>51284</obo:OGG_0000000006>
        <obo:OGG_0000000006>54106</obo:OGG_0000000006>
        <obo:OGG_0000000006>8829</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5006</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CLEC4C</rdfs:comment>
        <rdfs:comment>Gene name: IL13RA2</rdfs:comment>
        <rdfs:comment>Gene name: NRP1</rdfs:comment>
        <rdfs:comment>Gene name: TLR7</rdfs:comment>
        <rdfs:comment>Gene name: TLR9</rdfs:comment>
        <rdfs:label>plasmacytoid dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007098 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007098">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007098</metadata:prefixIRI>
        <obo:IAO_0000115>rime/boost vaccination proved to be of no advantage or even detrimental in therapeutic settings in B16F1 and transgenic adenocarcinoma of the mouse prostate (TRAMP) models, respectively</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:23539449</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4074</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/140</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4074</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>prime/boost DC-TRP-2 melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007099">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007099</metadata:prefixIRI>
        <obo:IAO_0000115>A melanoma vaccine comprised of a recombinant fowlpox vector construct encoding a modified epitope of the melanoma antigen glycoprotein 100 (gp100), ES-2092M(gp100), containing an endoplasmic reticulum signal sequence targeted to the endoplasmic reticulum apparatus. Vaccination with recombinant fowlpox-gp100p209 vaccine may stimulate the host immune system more efficiently to mount a cytotoxic T lymphocyte response against tumor cells expressing the gp100 antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2806</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00080353</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5274</obo:IAO_0000119>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5274</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>recombinant Fowlpox-gp100p209 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007100</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a replication-defective recombinant fowlpox virus that encodes for the murine melanoma antigen glycoprotein 100 (mgp100) with potential antineoplastic activity. Vaccination with recombinant fowlpox-mgp100 vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2805</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5499</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/332</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5499</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>recombinant Fowlpox-Mgp100 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007101">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007101</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant fowlpox virus vaccine with potential antineoplastic activity. Binding to the melanoma antigen tyrosinase, recombinant fowlpox-tyrosinase vaccine generates cellular immune responses against melanoma cells expressing the tyrosinase antigen; this effect is enhanced by the co-administration of interleukin 2 (IL-2). Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2807</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00054535</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5518</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/335</obo:IAO_0000233>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5518</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:label>recombinant Fowlpox-Tyrosinase vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007102 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007102">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007102</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant chaperone-peptide complex-based vaccine composed of a complex between heat shock protein hsp110 and the human melanoma-associated antigen gp100, with potential antineoplastic activity. Upon vaccination, recombinant hsp110-gp100 chaperone complex activates the immune system to exert a cytotoxic T cell immune response and antigen-specific interferon-gamma production against gp100-overexpressing cancer cells. Gp100, is overexpressed in a variety of cancer cell types. Hsp110, binds to and chaperones full-length proteins during heat shock; as an immunoadjuvant it is able to enhance an immune response against antigen(s) and stimulate T-lymphocyte activation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C103830</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01744171</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12750279</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5359</obo:IAO_0000119>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5359</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>recombinant human Hsp110-gp100 chaperone complex vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007103 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007103</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant vaccinia virus encoding a modified peptide of the gp100 melanoma-melanocyte antigen with potential use in cancer immunotherapy. gp100 human antigen is a wild type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas. gp100p209 is a fragment epitope of gp100 in which the threonine in position 2 is replaced with methionine; this modification may stimulate tumor infiltrating lymphocytes (TIL) more efficiently.‚Äö√†√∂‚àö¬ß</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29566</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00116597</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:15133631</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5393</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/344</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5393</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>recombinant Vaccinia-gp100:209-217 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007104 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007104</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant vaccinia virus encoding a modified peptide of the gp100 melanoma-melanocyte antigen with potential use in cancer immunotherapy. gp100 human antigen is a wild type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas. This recombinant vaccinia Mgp100 encodes a fragment epitope of gp100 bearing 2 amino acids substitution; T-&gt;M at position 210 and 288 A -&gt;V at position 210. This modification may stimulate tumor infiltrating lymphocytes (TIL) more efficiently.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C51978</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12912944</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5505</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/346</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5505</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>recombinant Vaccinia-Mgp100 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007105 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007105</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of an inactivated recombinant vaccinia virus encoding epitope peptides derived from melanoma-related HLA-A2-restricted tumor-associated antigens (TAAs), including Melan-A(27-35), gp100(280-288) and tyrosinase(1-9), and two co-stimulatory B7 proteins, B7.1 (CD80) and B7.2 (CD86). Upon administration, recombinant vaccinia-multiepitope melanoma peptides-B7.1-B7.2 vaccine may stimulate a cytotoxic T-lymphocyte response against melanoma cells that express TAAs which share epitopes with the epitope peptides expressed by the vaccine viral vector, resulting in tumor cell lysis; vaccine viral vector-expressed co-stimulatory proteins B7.1 and B7.2 may enhance the cytotoxic T-lymphocyte immune response to the TAAs.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C48638</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:30626434</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5232</obo:IAO_0000119>
        <obo:OGG_0000000006>12524</obo:OGG_0000000006>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5232</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:comment>Gene name: Cd86</rdfs:comment>
        <rdfs:comment>Gene name: MLANA-Dupli</rdfs:comment>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>recombinant Vaccinia-multiepitope melanoma peptides-B7.1-B7.2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007106 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007106</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant vaccinia virus encoding the melanocyte differentiation antigen tyrosinase-related protein-1 (TRP-1) with potential use in cancer immunotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29564</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:19047169</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5063</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/352</obo:IAO_0000233>
        <obo:OGG_0000000006>22178</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5063</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TRP-1</rdfs:comment>
        <rdfs:label>recombinant Vaccinia-TRP1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007107 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007107</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine adjuvant consisting of a plasmid DNA encoding sargramostim (a granulocyte macrophage-colony stimulating factor). Upon administration, expressed sargramostim may stimulate a cytotoxic T cell response enhancing the host immune response to a concomitantly administered melanoma vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2430</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01216436</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26241951</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5194</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/360</obo:IAO_0000233>
        <obo:OGG_0000000006>1493</obo:OGG_0000000006>
        <obo:OGG_0000000006>8784</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5194</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTLA4</rdfs:comment>
        <rdfs:comment>Gene name: TNFRSF18</rdfs:comment>
        <rdfs:label>Sargramostim Plasmid DNA Melanoma Vaccine Adjuvant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007108 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007108">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007108</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant plasmid DNA vaccine that encodes two peptides, tyrosinase 207-216 and tyrosinase 1-17,  both of which are derived from human tyrosinase.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/697"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0007109"/>
        <rdfs:label>obsolete Synchotrope TA2M vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007109 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007109</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant plasmid DNA vaccine encoding epitopes of tyrosinase with potential antineoplastic activity. Synchotrope TA2M vaccine contains a plasmid encoding 2 epitopes, amino acid sequences 207-216 and 1-17 of tyrosinase, a protein frequently expressed by melanoma cells. Vaccination with the TA2M plasmid DNA vaccine may induce the production of anti-tyrosinase antibodies as well as elicit a cytotoxic T-lymphocyte (CTL) response against tyrosinase-expressing tumor cells, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2650</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00023647</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12833467</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4002</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5218</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/407</obo:IAO_0000233>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4002</obo:VO_0001818>
        <obo:VO_0001818>5218</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:label>Synchotrope TA2M DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007110 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007110">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007110</metadata:prefixIRI>
        <obo:IAO_0000115>A bivalent DNA vaccine encoding epitopes for both Melan-A (MART-1) and tyrosinase with potential antineoplastic activity. Synchrovax SEM plasmid DNA vaccine contains a plasmid pSEM that encodes 4 epitopes: Melan-A (26-35), Melan-A (31-96), tyrosinase (1-9), and tyrosinase (369-377). Both Melan-A and tyrosinase are tumor antigens associated with melanoma. Vaccination with this plasmid DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) responses against cells expressing either or both of these antigens, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C28549</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00033228</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5506</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/408</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5506</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA-Dupli</rdfs:comment>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:label>Synchrovax SEM plasmid DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007111 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007111">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007111</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing synthetic epitope peptides derived from melanoma tumor-associated antigens (TAAs), including melanoma-melanocyte antigen gp100(280-288), melanoma-associated antigen tyrosinase(1-9), and melanoma-associated antigen melan-A(27-35). Upon administration, synthetic melanoma-associated antigens vaccine may stimulate a cytotoxic T-lymphocyte immune response against melanoma cells that express TAAs which share epitopes with the vaccine epitope peptides, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C48639</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00116597</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11874634</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5217</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/411</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5217</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PMEL - obsolete</rdfs:comment>
        <rdfs:label>synthetic melanoma-associated antigens vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007112 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007112">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007112</metadata:prefixIRI>
        <obo:IAO_0000115>A RNA-lipoplex (RNA-LIP)-based cancer vaccine containing four naked ribonucleic acid (RNA)-drug products (DPs) RBL001.1, RBL002.2, RBL003.1, and RBL004.1 encoding the four melanoma-associated antigens (MAAs), the cancer-testis antigen NY-ESO-1, the human melanoma-associated antigen A3 (MAGE-A3), tyrosinase, and putative tyrosine-protein phosphatase (TPTE), encapsulated in liposomes, with potential antineoplastic activity. Upon intravenous administration of the tetravalent RNA-lipoplex cancer vaccine BNT111, the liposomes protect the RNA from degradation in the bloodstream, travel to the spleen and are taken up by antigen-presenting cells (APCs). The RNA is translocated to the cytoplasm and translated into the four tumor-associated proteins. The expressed proteins are processed and the human leukocyte antigen (HLA)-peptide complexes are presented to the immune system. This results in the production of various pro-inflammatory cytokines and induces antigen-specific CD8+ and CD4+ T-cell responses against the four selected MAAs NY-ESO-1, MAGE-A3, tyrosinase, and TPTE.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C122396</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02410733</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:21093980</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5114</obo:IAO_0000119>
        <obo:OGG_0000000006>416115</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5114</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGE-1</rdfs:comment>
        <rdfs:label>tetravalent RNA-lipoplex cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007113 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007113">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007113</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:23090079</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4004</obo:IAO_0000119>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6409</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4004</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: PMEL</rdfs:comment>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:label>TLR-9/GM vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007114 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007114</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:23509826</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4075</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4075</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>TriMixDC-MEL Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007115 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007115</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant peptide consisting of amino acid residues 180 to 188 of the tyrosinase-related protein 2 (TRP2). Expressed by cells of melanocyte origin, TRP2 is an enzyme involved in the process that converts tyrosinase to melanin pigments. Vaccination with TRP-2: 180-188 peptide may induce cytotoxic T lymphocyte (CTL) responses to melanoma cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2815</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00022438</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16906394</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5325</obo:IAO_0000119>
        <obo:OGG_0000000006>1638</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5325</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TRP-2</rdfs:comment>
        <rdfs:label>TRP-2: 180-188 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007116 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007116">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007116</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant peptide consisting of amino acid residues 1 to 9 of the tyrosinase-related protein 1 (TRP1). Expressed by cells of melanocyte origin, TRP1 is an enzyme involved in the process that converts tyrosinase to melanin pigments. Vaccination with TRP1(0RF3):1-9 may stimulate cytotoxic T cell responses to melanoma cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2816</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00019383</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:8027058</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5487</obo:IAO_0000119>
        <obo:OGG_0000000006>22178</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5487</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TRP-1</rdfs:comment>
        <rdfs:label>TRP1(0RF3):1-9 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007117 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007117">
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007117</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine containing a tyrosinase epitope conjugated with keyhole lymphocyte hemocyanin (KLH) with potential antineoplastic activity. Tyrosinase, one of the melanoma differentiation antigens, is the rate-limiting enzyme for melanin synthesis. This tyrosine epitope is conjugated with KLH, which serves as an immunostimulant and a hapten carrier, to enhance immune recognition. Vaccination with tyrosinase-KLH peptide vaccine may produce anti-tyrosinase antibodies as well as elicit a cytotoxic T lymphocyte (CTL) response against cells expressing tyrosinase antigen, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2384</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00028431</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:21143299</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5060</obo:IAO_0000119>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5060</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:label>tyrosinase-KLH vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007118 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007118">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007118</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:14581425</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3999</obo:IAO_0000119>
        <obo:IAO_0000119>tyrosinase240-251s, 368-376d vaccine</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3999</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>tyrosinase240-251S, 368-376D vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007119</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine with VMCL was not associated with a statistically significant improvement in OS or RFS, with CIs not ruling out important gains from such treatment.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:12377961</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4007</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4007</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>vaccinia melanoma cell lysates (VMCL) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007120</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:3155379</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4023</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4023</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaccinia melanoma oncolysates (VMO) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007121">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007121</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant vaccinia virus that encodes granulocyte-macrophage colony stimulating factor (GM-CSF). By activating T-cells and macrophages, vaccination with recombinant vaccinia GM-CSF may enhance the host immune system response to poorly immunogenic tumors, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2674</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00002817</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:8894677</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5508</obo:IAO_0000119>
        <obo:OGG_0000000006>12981</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5508</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Csf2-Mouse</rdfs:comment>
        <rdfs:label>Vaccinia-GM-CSF vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007122 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007122">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007122</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of recombinant vaccinia virus, based on the modified vaccinia virus Ankara (MVA) that encodes the melanoma-associated antigen tyrosinase. Vaccination with vaccinia-tyrosinase may stimulate the host immune system to mount a cytotoxic T-cell response against tumor cells expressing tyrosinase. Tyrosinase is a melanoma-specific differentiation agent that catalyzes the synthesis of the melanin precursor L-3,4-dihydroxyphenylalanine (L-DOPA).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2531</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00019734</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5223</obo:IAO_0000119>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5223</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:label>Vaccinia-Tyrosinase vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007123 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007123">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007123</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA vaccine, encoding an epitope of mouse tyrosinase, with potential antineoplastic activity. Administered via intramuscular electroporation, vaccination with xenogeneic tyrosinase DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) immune responses against melanoma cells that express tyrosinase, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C68839</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00471133</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:4019903</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5416</obo:IAO_0000119>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5416</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:label>Xenogeneic Tyrosinase DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007124 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007124">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005491"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007124</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant replication-defective adenovirus which encodes the gene for the cytokine human interferon-beta (IFN-beta). Once inserted into and replicating in host tumor cells, recombinant adenovirus-hIFN-beta expresses human IFN-beta, which may stimulate an antiproliferative natural killer (NK) cell response against tumor cells and induce caspase-mediated tumor cell apoptosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C28550</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00066404</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:19893592</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5510</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/321</obo:IAO_0000233>
        <obo:OGG_0000000006>3456</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005065"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5510</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IFNB1</rdfs:comment>
        <rdfs:label>Recombinant Adenovirus-hIFN-beta Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007125 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007125">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005492"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007125</metadata:prefixIRI>
        <obo:IAO_0000115>A modified recombinant nonapeptide (LMLGEFLKL) derived from the anti-apoptosis protein survivin with potential immunopotentiating and antineoplastic activities. Upon administration, survivin Sur1M2 peptide vaccine may elicit humoral and cellular immune responses against survivin-expressing cancers, resulting in decreased tumor cell proliferation and tumor cell death. The survivin protein inhibits caspase activation and apoptosis; it is undetectable in normal adult tissues but is expressed by several human cancers including lung, colon, breast, pancreas, and prostate cancer as well as hematopoietic malignancies and skin cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C71741</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00499577</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:29057249</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5265</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/365</obo:IAO_0000233>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5265</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>Survivin Sur1M2 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007126 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007126">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005492"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007126</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of myeloma-specific immunoglobulin that is not conjugated to a carrier molecule. Vaccination with unconjugated myeloma Ig Id may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against myeloma cells, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2822</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00001561</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:4108872</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5391</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5391</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Unconjugated Myeloma Ig Id Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007127 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007127</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine comprised of an epitope of human Wilms tumor 1 (WT-1) with potential antineoplastic activity. WT-1, a transcription factor, is overexpressed in most types of leukemia and in some solid cancers. Vaccination with the WT-1 analog peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against WT-1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C64635</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01827137</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:25802083</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5341</obo:IAO_0000119>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5341</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>WT1 Analog Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007128 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007128">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007128</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide cancer vaccine comprised of a peptide derived from Wilms tumor gene 1 (WT1) protein, with potential immunomodulating and antineoplastic activities. Upon administration, WT2725 may induce a specific cytotoxic T-lymphocyte (CTL) response against WT1-overexpressing tumor cells. WT1 protein, a zinc finger DNA-binding protein, is overexpressed in leukemic cells and in a vast number of non-hematological solid tumors.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C102751</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01621542</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5027</obo:IAO_0000119>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5027</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>WT1 Peptide Vaccine WT2725</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007129 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007129">
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007129</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing immunogenic, HLA-A2-specific epitopes derived from X-box-binding protein 1-unspliced (XBP1-US), XBP1-spliced (SP), syndecan-1 (CD138), and CS1 (CD2 subset 1, CRACC, SLAMF7, CD319) with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration, XBP1-US/XBP1-SP/CD138/CS1 multipeptide vaccine PVX-410 may stimulate the immune system to induce a cytotoxic T-lymphocyte response against the four myeloma-specific antigens. The tumor associated antigens (TAAs) XBP1-US, XBP1-SP, CD138 and CS1, are overexpressed on the surface of multiple myeloma (MM) cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C103823</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01718899</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:30128502</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5415</obo:IAO_0000119>
        <obo:OGG_0000000006>22433</obo:OGG_0000000006>
        <obo:OGG_0000000006>57823</obo:OGG_0000000006>
        <obo:OGG_0000000006>6382</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5415</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: SDC1</rdfs:comment>
        <rdfs:comment>Gene name: SLAMF7</rdfs:comment>
        <rdfs:comment>Gene name: Xbp1</rdfs:comment>
        <rdfs:label>XBP1-US/XBP1-SP/CD138/CS1 Multipeptide Vaccine PVX-410</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007130 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007130">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007130</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous dendritic cells (DCs) loaded with autologous, lethally irradiated cancer cells and mixed with the cytokine granulocyte-macrophage colony stimulating factor (GM-CSF), with potential immunostimulatory and antineoplastic activities. Upon vaccination, ovapuldencel-T may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against the repertoire of tumor associated antigens (TAAs) found in the irradiated cancer cells. GM-CSF enhances the activation of dendritic cells (DCs) and promotes antigen presentation to both B- and T-lymphocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C113651</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02033616</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5481</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/71</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5481</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Ovapuldencel-T Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007131 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007131">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007131</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of synthetic peptides corresponding to naturally-occurring peptides derived from ovarian cancer cell antigens. Ovarian cancer peptide vaccine may elicit a cytotoxic T-cell response against tumor cells expressing the related ovarian cancer cell antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C48414</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00091273</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:20445345</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5502</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5502</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Ovarian Cancer Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007132 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007132</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing autologous dendritic cells (DCs) that are transfected with mRNAs extracted from amplified ovarian cancer stem cells, and mRNAs of the universal tumor antigens human telomerase reverse transcriptase (hTERT) and survivin with potential immunostimulatory and antineoplastic activities. Upon administration, ovarian cancer stem cell/hTERT/survivin mRNAs-loaded autologous DC-006 vaccine may elicit a highly specific cytotoxic T-cell (CTL) response against ovarian cancer cells expressing hTERT, survivin, and specific ovarian cancer stem cell antigens. hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types, playing key roles in tumor cell growth and survival. Ovarian cancer stem cells contain a specific range of antigens that are essential for the neoplastic growth and survival of ovarian cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C96739</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01334047</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5403</obo:IAO_0000119>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5403</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>Ovarian Cancer Stem Cell/hTERT/Survivin mRNAs-loaded Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007133 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007133</metadata:prefixIRI>
        <obo:IAO_0000115>A dendritic cell (DC)-based cancer vaccine composed of autologous dendritic cells (DCs) activated with an ovarian tumor cell lysate containing tumor-associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, the ovarian tumor antigen-activated autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against ovarian cancer cells expressing ovarian tumor cell-specific antigens, which may result in ovarian tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C115105</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02107950</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:22862954</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5280</obo:IAO_0000119>
        <obo:OGG_0000000006>3696</obo:OGG_0000000006>
        <obo:OGG_0000000006>3728</obo:OGG_0000000006>
        <obo:OGG_0000000006>780</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5280</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: DDR1</rdfs:comment>
        <rdfs:comment>Gene name: ITGB8</rdfs:comment>
        <rdfs:comment>Gene name: JUP</rdfs:comment>
        <rdfs:label>Ovarian Tumor Antigen-activated Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007134 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007134</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine consisting of 10 synthetic long peptides (SLPs), 25-30 amino acids in size and derived from the middle portion of p53 (amino acids 70-251), mixed with the adjuvant Montanide ISA-51 with potential immunostimulatory and antitumor activities. Upon administration, p53 synthetic long peptide (70-251) vaccine may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL) response against p53-expressing tumor cells. p53, a tumor associated antigen (TAA), may be overexpressed in variety of cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C82420</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00844506</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26334096</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5278</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/59</obo:IAO_0000233>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5278</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TP53</rdfs:comment>
        <rdfs:label>P53-Synthetic Long Peptides Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007135 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007135</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine with potential antineoplastic activity. PA-1-STK ovarian carcinoma vaccine is produced by transducing the ovarian cancer cell line, PA-1, with the herpes simplex thymidine kinase (HSV-tk) gene, resulting in a cell line, PA-1-STK, that permanently expresses the HSV tk gene. Upon transfection into malignant cells, this vaccine is capable of sensitizing tumor cells in response to an antiviral drug such as ganciclovir, which is readily phosphorylated by the TK enzyme to its active form. Administration of ganciclovir following PA-1 STK transfection results in enhanced cytotoxicity of the transfected tumor cells. Additionally, adjacent non-transfected cells are also killed by the activated antiviral drug, a phenomenon referred to as the bystander effect that occurs with this type of suicide-gene transfer technique.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2428</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00006216</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:7578411</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5245</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/57</obo:IAO_0000233>
        <obo:OGG_0000000006>79447</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5245</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PAGR1</rdfs:comment>
        <rdfs:label>PA-1-STK Ovarian Carcinoma Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007136 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007136</metadata:prefixIRI>
        <obo:IAO_0000115>An oncolytic thymidine kinase (TK)-deleted vaccinia poxvirus expressing human GM-CSF (hGM-CSF) with antineoplastic activity. Upon intratumoral or intravenous administration, pexastimogene devacirepvec selectively infects and lyses tumor cells. While vaccinia displays a natural tumor cell tropism, deletion of the TK gene increases the tumor selectivity of vaccinia by limiting viral replication to cells expressing high levels of TK, such as certain cancer cells. hGM-CSF expression by this agent helps recruit antigen presenting cells (APCs), such as dendritic cells (DCs) and macrophages, to virally infected tumor cells, thereby initiating an antitumoral immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C71533</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02562755</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:31413923</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5078</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/119</obo:IAO_0000233>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5078</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: hGM-CSF</rdfs:comment>
        <rdfs:label>Pexastimogene-devacirepvec Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007137 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007137</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA vaccine containing mammalian expression vector pUMVC3, encoding epitopes of human insulin-like growth factor-binding protein 2 (hIGFBP-2) with potential immunostimulating and antineoplastic activities. Upon vaccination, pUMVC3-hIGFBP-2 multi-epitope plasmid DNA vaccine may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against hIGFBP-2-expressing cells. The tumor associated antigen (TAA) hIGFBP-2, a member of the insulin like growth factor receptor family, is overexpressed in a number of cancer cell types and its expression has been associated with increased invasiveness.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C95727</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01322802</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:17102977</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5365</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/186</obo:IAO_0000233>
        <obo:OGG_0000000006>3484</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5365</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: hIGFBP-2</rdfs:comment>
        <rdfs:label>pUMVC3-hIGFBP-2 Multi-Epitope Plasmid DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007138 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007138</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant retrovirus containing the modified murine retroviral vector MFG-S encoding a chimeric construct, MOv18-gamma. MOv18 is a murine monoclonal antibody developed against epitope of human folate binding protein, which is overexpressed on more than 90% of non-mucinous epithelial ovarian neoplasms. The chimeric construct (MOv18-gamma) encodes the variable region of MOv18 antibody, and the gamma chain of human T-cell receptor. This virion might be used to transduce autologous T lymphocytes, and reintroduced back to the patient after expansion ex vivo to invoke specific immune response against ovarian cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29192</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5131</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/356</obo:IAO_0000233>
        <obo:OGG_0000000006>2348</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5131</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FOLR1</rdfs:comment>
        <rdfs:label>Retroviral Vector MFGS-MOv18-gamma Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007139 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007139">
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007139</metadata:prefixIRI>
        <obo:IAO_0000115>A fowlpox vaccine containing the tumor-associated antigen mucin-1 (MUC1), found in pancreatic tumor cells, and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; TRICOM), which is designed to enhance antigen presentation and activation of immune responses critical for tumor destruction. Vaccination with this agent may elicit a host immune response against MUC1-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29558</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5477</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/357</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5477</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>rF-MUC1(DF3)/TRICOM Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007140 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007140">
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        </rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007140</metadata:prefixIRI>
        <obo:IAO_0000115>A whole cell vaccine comprised of irradiated allogenic pancreatic tumor cells transfected with a plasmid DNA encoding human sargramostim (GM-CSF). Vaccination results in expression of GM-CSF, which induces proliferation and differentiation hematopoietic lineage cells as well as stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Furthermore, administration of this pancreatic tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2445</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00389610</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5340</obo:IAO_0000119>
        <obo:OGG_0000000006>100137216</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5340</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:label>Sargramostim Plasmid DNA Pancreatic Tumor Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007141 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007141">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007141</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine containing an HLA-A*2402-restricted epitope of vascular endothelial growth factor receptor 1 (VEGFR1 or Flt-1) with potential immunostimulating, antiangiogenic, and antineoplastic activities. Upon vaccination, VEGFR1-1084 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against VEGFR1-expressing endothelial cells of the tumor microvasculature, which may inhibit tumor angiogenesis and tumor cell proliferation. VEGFR1, a receptor tyrosine kinase, may be overexpressed on endothelial cells of the tumor microvasculature and is associated with tumor cell proliferation, invasion and tumor angiogenesis. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C77895</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00655785</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:26190488</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5214</obo:IAO_0000119>
        <obo:OGG_0000000006>2321</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5214</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FLT1</rdfs:comment>
        <rdfs:label>VEGFR1-1084 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007142 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007142">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007142</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine containing an HLA-A*2402-restricted epitope of vascular endothelial growth factor receptor (VEGFR) 2 with potential immunostimulatory and antineoplastic activities. Upon administration, VEGFR2-169 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against VEGFR2-expressing tumor cells. VEGFR2, a receptor tyrosine kinase, is overexpressed by a variety of tumor types; overexpression is associated with tumor cell proliferation and tumor angiogenesis. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenic peptide immunogenicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C74090</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00639925</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:15930316</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5419</obo:IAO_0000119>
        <obo:OGG_0000000006>16542</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5419</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Kdr</rdfs:comment>
        <rdfs:label>VEGFR2-169 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007143 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007143</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing HLA class I- and II-binding peptides derived from the NY-ESO-1/LAGE-1 cancer/testis antigen with potential immunostimulatory and antineoplastic activities. Upon administration, NY-ESO-1/LAGE-1 HLA class I/II peptide vaccine may induce a cytotoxic immune response against tumor cells that over-express NY-ESO-1/LAGE-1. Rarely expressed by normal cells, the NY-ESO-1/LAGE-1 cancer/testis antigen has been shown to be preferentially expressed on the surface of some cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C74066</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00616291</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:21131422</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5379</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/111</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>30848</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5379</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:comment>Gene name: CTAG2</rdfs:comment>
        <rdfs:label>NY-ESO-1/LAGE-1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007144 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007144</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous dendritic cell (DCs) vaccine targeting prostate cancer with immunostimulating activity. The autologous DC vaccine is prepared via transfecting DCs with mRNAs extracted from primary prostate cancer tissue, and mRNAs of human telomerase reverse transcriptase (hTERT) and survivin. Upon administration, this DC vaccine may elicit a potent cytotoxic T-cell (CTL) response against prostate cancer cells, resulting in tumor cell death. Both hTERT and survivin are essential in neoplastic growth, and are considered to be universal tumor antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C95771</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00345293</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:30505813</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5205</obo:IAO_0000119>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5205</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>Primary Prostate Cancer Tissue/hTERT/Survivin mRNA-loaded Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007145 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007145</metadata:prefixIRI>
        <obo:IAO_0000115>This DNA vaccine expressed prostate-specific membrane antigen (PSMA)</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22729556</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3710</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3710</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Prostate cancer DNA vaccine pDOM-PSMA27 encoding PSMA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007146">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007146</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based vaccine derived from prostate cancer with potential immunopotentiating and antineoplastic activities. Prostate cancer vaccine ONY-P1 is derived from three irradiated allogeneic prostate cancer cell lines that represent different stages of prostate cancer and express a broad range of prostate and prostate cancer antigens. Upon administration, this vaccine may stimulate a host immune response against prostate cancer cells; in the vaccination schedule, the first two vaccinations are co-administered with bacillus Calmette-Guerin (BCG) as an adjuvant.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C71723</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00514072</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:22932804</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5351</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/141</obo:IAO_0000233>
        <obo:OGG_0000000006>959</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5351</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40</rdfs:comment>
        <rdfs:label>Prostate Cancer Vaccine ONY-P1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007147 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007147</metadata:prefixIRI>
        <obo:IAO_0000115>A dendritic cell (DC)-based cancer vaccine composed of autologous dendritic cells (DCs) activated with a prostate tumor cell lysate containing tumor-associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, the prostate tumor antigen-activated autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against prostate cancer cells expressing prostate tumor cell-specific antigens, which may result in prostate tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C115106</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02111577</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27683469</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5132</obo:IAO_0000119>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5132</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>Prostate Tumor Antigen-activated Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007148 -->

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            </owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007148</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccinia virus carrying a copy of the human gene encoding prostate-specific antigen (PSA), contaminated with bovine viral diarrhea virus (BVDV).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29334</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27683469</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5260</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/142</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5260</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>PROSTVAC-Contaminated W/ BVDV vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007149 -->

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        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007149</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine containing the prostate specific antigen (PSA) with potential antineoplastic activity. PSA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed in prostate cancer cells and is used as a tumor marker for both diagnosis and treatment evaluation. Vaccination with PSA peptide vaccine may produce anti-PSA antibodies as well as elicit a cytotoxic T-cell (CTL) response against prostate cancer cells expressing this antigen, thereby decreasing tumor cell growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2497</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00015977</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27683469</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5087</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/143</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5087</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>PSA Prostate Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007150</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous dendritic cell vaccine with potential immunostimulatory activity. Dendritic cells harvested from a prostate cancer patient are transfected with the mRNA encoding for prostate specific antigen (PSA), a tumor marker secreted by prostatic epithelial and ductal cells. When reintroduced back to the patient, these PSA RNA pulsed autologous dendritic cells may elicit a cytotoxic T-cell (CTL) response against PSA-positive prostate cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2236</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00004211</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:14711334</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5022</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/144</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5022</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>PSA RNA-Pulsed Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007151 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007151">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007151</metadata:prefixIRI>
        <obo:IAO_0000115>A 30-residue prostate specific antigen (PSA) oligoepitope peptide (OP) vaccine with potential antineoplastic activity. PSA-OP peptide vaccine contains the PSA-1 and PSA-3 HLA-A2 epitopes and the PSA-9 HLA-class I-A3 epitope joined by peptide linker sequences. In an animal model, vaccination with this agent has been shown to elicit a cytotoxic T-lymphocyte immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C29337</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:9743387</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5234</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/179</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5234</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>PSA-OP Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007152 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007152">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007152</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with the prostate-specific tumor associated antigens (TAAs) prostate specific antigen (PSA) and prostate acid phosphatase (PAP), and conjugated to the immunostimulant keyhole limpet hemocyanin (KLH), with potential immunostimulatory and antineoplastic activities. Upon administration, prostate cancer antigen/KLH-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against prostate cancer cells expressing PSA and PAP, which may result in prostate cancer cell lysis. KLH is an immunogenic carrier and serves as an immunostimulant to improve antigenic immune recognition and T-cell responses and can be used to evaluate vaccine efficacy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C92573</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01171729</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12487060</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5353</obo:IAO_0000119>
        <obo:OGG_0000000006>56318</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5353</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Acpp</rdfs:comment>
        <rdfs:label>PSA-PAP/KLH-pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007153 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007153</metadata:prefixIRI>
        <obo:IAO_0000115>A prostate cancer vaccine containing prostate specific antigen (PSA) combined with the cytokines, interleukin-2 (IL-2) and granulocyte macrophage-colony-stimulating factor (GM-CSF), with potential antineoplastic activity. Upon intradermal vaccination, PSA/IL-2/GM-CSF vaccine may activate the immune system to induce a cytotoxic T-cell (CTL) response against prostate cancer cells expressing this antigen, thereby decreasing tumor cell growth. PSA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed by prostate cancer cells. IL-2 stimulates natural killer (NK) cells and cytotoxic T-cells against the PSA-expressing tumor cells. GM-CSF promotes antigen presentation to dendritic cells and further stimulates a tumor-specific cytotoxic T-lymphocyte (CTL) response.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
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        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02058680</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12487060</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5109</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/180</obo:IAO_0000233>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
        <obo:OGG_0000000006>3558</obo:OGG_0000000006>
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        <obo:VO_0001818>5109</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:comment>Gene name: IL-2</rdfs:comment>
        <rdfs:label>PSA/IL-2/GM-CSF Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007154 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007154</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA vaccine encoding the tumor-associated antigens (TAAs) prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA), with potential immunoactivating and antineoplastic activities. Upon intramuscular delivery and electroporation of the PSA/PSMA DNA plasmid INO-5150, both PSA and PSMA are translated in cells which then activate the immune system. This induces cytotoxic T-lymphocyte (CTL) responses against tumor cells expressing PSA and PSMA. This may result in both immune-mediated tumor cell death and the inhibition of tumor cell proliferation. PSA and PSMA are overexpressed on a variety of cancer cell types. The DNA encoding the TAAs in INO-5150 is based on both human and other primate antigen gene sequences. As the plasmid genes differ from the human gene sequences encoding these antigens, INO-5150 may overcome immune tolerance to human TAAs.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C123283</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02514213</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:32208168</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5252</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/181</obo:IAO_0000233>
        <obo:OGG_0000000006>2346</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5252</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FOLH1</rdfs:comment>
        <rdfs:label>PSA/PSMA DNA Plasmid INO-5150 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007155 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007155</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide based on sequence corresponding to positions 154-163 of the amino acids of prostate-specific antigen (PSA), VISNDVCAQV. Upon administration, PSA:154-163 peptide vaccine may elicit a cytotoxic T-cell response against tumor cells that express PSA.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2798</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00004156</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:19483644</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5106</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/182</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5106</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>PSA:154-163 Peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007156 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007156</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a synthetic peptide with an amino acid sequence corresponding to positions 154-163 of the amino acid sequence for prostate-specific antigen (PSA) with a leucine substitution at position 155. Upon administration, PSA:154-163(155L) peptide vaccine may elicit a cytotoxic T-cell response against tumor cells that express PSA.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C29338</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00109811</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:19483644</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5155</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/183</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5155</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>PSA:154-163(155L) Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007157 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007157</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide-based cancer vaccine containing epitopes of T cell receptor gamma-chain alternate reading frame protein (TARP) and prostate-specific membrane antigen (PSMA) in combination with a Poly IC-LC immunoadjuvant, with potential antineoplastic activity. Upon administration, PSMA/TARP peptide vaccine may stimulate a host cytotoxic T-cell (CTL) response against TARP- and PSMA-expressing tumor cells, resulting in tumor cell cytotoxicity. The nuclear protein TARP and PSMA are commonly expressed in prostate cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C78819</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00694551</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:34494382</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5052</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/184</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5052</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>PSMA/TARP Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007158 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007158</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing plasmid DNA encoding human prostatic acid phosphatase (PAP) (pTVG-HP) with potential immunostimulatory and antineoplastic activities. Upon administration, pTVG-HP plasmid DNA vaccine may stimulate the host immune system to generate a cytotoxic T lymphocyte (CTL) response against PAP-expressing prostate cancer cells. PAP or prostatic specific acid phosphatase (PSAP) is a tumor associated antigen (TAA) that may be overexpressed in prostate cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C82407</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02499835</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:17102977</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5535</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/185</obo:IAO_0000233>
        <obo:OGG_0000000006>55</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5535</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ACP3</rdfs:comment>
        <rdfs:label>pTVG-HP Plasmid DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007159 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007159</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing xenogenic DNA from rhesus macaque (Macaca mulatta) that encodes prostate specific antigen (PSA) with potential immunostimulating and antineoplastic activities. Upon repeated intradermal administration via electroporation, pVAXrcPSAv53l vaccine may induce a cytotoxic T-lymphocyte (CTL) response against PSA-expressing prostate cancer cells. Rhesus PSA is 89% homologous to human PSA.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C82352</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00859729</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5092</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/187</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5092</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>pVAXrcPSAv53l DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007160 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007160</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant fowlpox virus encoding human prostate-specific antigen (PSA). Administration of this agent may stimulate a cytotoxic T cell response against PSA-expressing tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2675</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00005039</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:17707059</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4988</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/333</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4988</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>Recombinant Fowlpox-Prostate Specific Antigen Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007161 -->

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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007161</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant fowlpox virus encoding fragment of human prostate-specific antigen (PSA), PSA:154-163 (155L), and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). Administration of this agent may induce a cytotoxic T cell response against PSA-expressing tumor cells. Dendritic cells infected with TRICOM vectors greatly enhance naive T-cell activation and peptide-specific T-cell stimulation. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C38708</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00108732</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:16390546</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5434</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/333</obo:IAO_0000233>
        <obo:OGG_0000000006>12519</obo:OGG_0000000006>
        <obo:OGG_0000000006>3383</obo:OGG_0000000006>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:OGG_0000000006>965</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5434</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD58</rdfs:comment>
        <rdfs:comment>Gene name: Cd80</rdfs:comment>
        <rdfs:comment>Gene name: ICAM1</rdfs:comment>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>Recombinant Fowlpox-PSA(L155)/TRICOM Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007162">
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007162</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a recombinant fowlpox virus vector encoding TRICOM. TRICOM is comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3) that may enhance antigen presentation and activate cytotoxic T-cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2667</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00450619</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5253</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/132</obo:IAO_0000233>
        <obo:OGG_0000000006>12519</obo:OGG_0000000006>
        <obo:OGG_0000000006>3383</obo:OGG_0000000006>
        <obo:OGG_0000000006>965</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5253</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD58</rdfs:comment>
        <rdfs:comment>Gene name: Cd80</rdfs:comment>
        <rdfs:comment>Gene name: ICAM1</rdfs:comment>
        <rdfs:label>Recombinant Fowlpox-TRICOM Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007163 -->

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        <obo:IAO_0000115>A vaccine consisting of recombinant vaccinia virus encoding prostate specific antigen (PSA). Vaccination with recombinant vaccinia prostate-specific antigen vaccine stimulates the host immune system to mount a cytotoxic T-cell response against tumor cells expressing PSA.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2433</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02649439</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12242725</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5154</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/339</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>Recombinant Vaccinia PSA Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007164 -->

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        <obo:IAO_0000115>A recombinant vaccinia virus encoding prostate-specific antigen (PSA). Vaccination with recombinant vaccinia-PSA may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for PSA, which may decrease tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29945</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00005039</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12242725</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5302</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/350</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
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        <obo:VO_0001818>5302</obo:VO_0001818>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>Recombinant Vaccinia-Prostate Specific Antigen Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007165 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007165</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant vaccinia virus encoding prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) with potential use in cancer immunotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5307</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/351</obo:IAO_0000233>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:comment>Gene name: Prostate-specific membrane antigen</rdfs:comment>
        <rdfs:label>Recombinant Vaccinia-PSA/PSMA Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007166 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007166</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic fowlpox viral vaccine containing the tumor-associated antigens prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; TRICOM). Vaccination with this viral vaccine may enhance antigen presentation and activate cytotoxic T-cells against PSA- or PSMA-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29559</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5005</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/358</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5005</obo:VO_0001818>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>rF-PSA/PSMA/TRICOM Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007167 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007167</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine formulation consisting of recombinant vaccinia virus encoding prostate specific antigen (PSA) and recombinant vaccinia virus encoding three co-stimulatory molecule transgenes B7.1, ICAM-1, and LFA-3 (TRICOM). Vaccination with PSA in combination with TRICOM may enhance antigen presentation, resulting in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells expressing PSA.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C38681</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02772562</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5183</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/359</obo:IAO_0000233>
        <obo:OGG_0000000006>12519</obo:OGG_0000000006>
        <obo:OGG_0000000006>3383</obo:OGG_0000000006>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:OGG_0000000006>965</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD58</rdfs:comment>
        <rdfs:comment>Gene name: Cd80</rdfs:comment>
        <rdfs:comment>Gene name: ICAM1</rdfs:comment>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>Rilimogene-galvacirepvec Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007168 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007168</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based vaccine composed of autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C1985</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02159950</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:20818862</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5216</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/362</obo:IAO_0000233>
        <obo:OGG_0000000006>55</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5216</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ACP3</rdfs:comment>
        <rdfs:label>Sipuleucel-T Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007169 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007169</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide vaccine, containing 16 amino acid residues (611-626) of the human telomerase reverse transcriptase catalytic subunit (hTERT), with potential antineoplastic activity. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation. Vaccination with tertomotide may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against telomerase-expressing cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C62756</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02855892</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:27941629</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5101</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/416</obo:IAO_0000233>
        <obo:OGG_0000000006>22059</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5101</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Trp53</rdfs:comment>
        <rdfs:label>Telomerase Peptide Vaccine GV1001</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007170 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007170">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007170</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic, peptide cancer vaccine directed against the human telomerase reverse transcriptase catalytic subunit (hTERT) with potential immunomodulating activity. Vaccination with the UV1 telomerase peptide may stimulate cytotoxic T-cells to recognize and kill telomerase-expressing cells. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01784913</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:28391357</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5478</obo:IAO_0000119>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5478</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>UV1 Telomerase Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007171 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007171">
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007171</metadata:prefixIRI>
        <obo:IAO_0000115>An adenovirus type 5 (Ad5) encoding human tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), with potential apoptosis-inducing and antineoplastic activities. Upon administration of recombinant Ad5 encoding TRAIL, the adenovirus selectively infects tumor cells and expresses TRAIL. The virally expressed TRAIL binds to and activates its receptors TRAIL receptor-1 (TRAIL-R1, death receptor 4, DR4) and TRAIL receptor-2 (TRAIL-R2, death receptor 5, DR5), which subsequently activate caspases and induce apoptosis in TRAIL-R1/R2-expressing tumor cells. The pro-apoptotic cell surface receptors TRAIL-R1 and -R2, members of the TNF receptor family, are overexpressed by a variety of cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C116879</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5397</obo:IAO_0000119>
        <obo:OGG_0000000006>8743</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5397</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TNFSF10</rdfs:comment>
        <rdfs:label>Recombinant Adenovirus 5 Encoding Tumor Necrosis Factor-related Apoptosis-Inducing Ligand Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007172 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007172">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007172</metadata:prefixIRI>
        <obo:IAO_0000115>A multipeptide cancer vaccine targeting renal cell carcinoma with potential immunopotentiating activity. Renal cell carcinoma peptides vaccine IMA901 consists of 10 different synthetic tumor-associated peptide (TUMAP) antigens (9 HLA-class I-binding and 1 HLA class II-binding); endogenously, these TUMAPs are expressed by the majority of renal cell carcinomas. Vaccination with this agent may significantly increase host cytotoxic T-lymphocyte (CTL) immune responses against tumor cells expressing these peptide antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C70968</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00523159</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:23899354</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5013</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/354</obo:IAO_0000233>
        <obo:OGG_0000000006>3105</obo:OGG_0000000006>
        <obo:OGG_0000000006>3106</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5013</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HLA-A</rdfs:comment>
        <rdfs:comment>Gene name: HLA-B</rdfs:comment>
        <rdfs:label>Renal Cell Carcinoma Peptides Vaccine IMA901</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007173 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007173</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based preparation in which autologous, mature dendritic cells (DCs) are electroporated with in vitro transcribed (IVT) RNAs encoding for a synthetic form of T-cell protein CD40 ligand (CD40L) and IVT RNA encoding for autologous tumor-associated antigens (TAAs) derived from patient-specific bladder cell carcinoma (BCC) cells, with potential immunostimulatory and antineoplastic activities. Upon electroporation into autologous DCs, the RNA is translated and processed. BCC-specific antigenic peptides are subsequently presented via major histocompatibility complex (MHC) Class I molecules on the DCs surface. When AGS-003-BLD is reintroduced to the patient, the MHC-presented peptides interact with and activate CD8-positive T cells, which elicits a highly specific cytotoxic T-cell (CTL) response against tumor cells expressing the patient-specific BCC TAAs. The signal cascade initiated by expression of the co-stimulatory molecule CD40L results in the secretion of the inflammatory cytokine IL-12, which further stimulates CTLs.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C129522</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02170389</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:25901286</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5373</obo:IAO_0000119>
        <obo:OGG_0000000006>958</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5373</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40</rdfs:comment>
        <rdfs:label>Renal Cell Carcinoma/CD40L RNA-Transfected Autologous Dendritic Cell Vaccine AGS-003</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007174 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007174</metadata:prefixIRI>
        <obo:IAO_0000115>Peripheral blood lymphocytes (PBL) harvested from the blood of a renal cancer patient and exposed in vitro to renal tumor-associated antigens (TAA). Introducing these renal tumor-reactive autologous peripheral blood lymphocytes back to the same patient target tumor cells expressing these TAAs and could induce a cytotoxic T-cell-mediated immune response against renal cell cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C48816</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:33408117</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5196</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5196</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Renal Tumor-Reactive Autologous Peripheral Blood Lymphocyte Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007175 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007175</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine consisting of amino acids 65 through 76 derived from the tumor suppressor protein Von Hippel-Lindau (VHL) with a glycine substitution at position 74. As a cancer vaccine, VHL-59: 65-76(V74G) may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C38122</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:20109232</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5097</obo:IAO_0000119>
        <obo:OGG_0000000006>7428</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5097</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: VHL</rdfs:comment>
        <rdfs:label>VHL-42: 65-76(V74G) Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007176 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007176</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine consisting of amino acids 116 through 128 derived from the tumor suppressor protein Von Hippel-Lindau (VHL) with a frameshift mutation. As a cancer vaccine, VHL-59: 116-128(FrSh116-128) peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C38123</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5172</obo:IAO_0000119>
        <obo:OGG_0000000006>7428</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5172</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: VHL</rdfs:comment>
        <rdfs:label>VHL-59: 116-128 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007177 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007177">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007177</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL14 peptide is a point mutation variant of the VHL protein; the mutation is in amino acid position 166. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2741</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5012</obo:IAO_0000119>
        <obo:OGG_0000000006>7428</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5012</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: VHL</rdfs:comment>
        <rdfs:label>VHL14 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007178">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007178</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL16 peptide, also known as S111I, is a point mutation variant of the VHL tumor suppressor protein; the mutation is in amino acid position 111. Vaccination with this agent may stimulate a cytotoxic T-cell response in patients with VHL-associated cancers that express this variant of the VHL tumor suppressor protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2740</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5333</obo:IAO_0000119>
        <obo:OGG_0000000006>7428</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5333</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: VHL</rdfs:comment>
        <rdfs:label>VHL16 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007179 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007179</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL2 (Y12M) peptide is a point mutation variant (from tyrosine to methionine at amino acid position 12) of the VHL protein. Vaccination with this peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C2824</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5490</obo:IAO_0000119>
        <obo:OGG_0000000006>7428</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5490</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: VHL</rdfs:comment>
        <rdfs:label>VHL2 (Y12M) Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007180 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007180">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007180</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of peptides derived from a tumor-associated protein encoded by a mutated Von Hippel-Lindau (VHL) oncogene. VHL peptide vaccine may stimulate a cytotoxic T cell response against tumor cells expressing the VHL tumor-associated protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2492</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00001703</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:20109232</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5127</obo:IAO_0000119>
        <obo:OGG_0000000006>7428</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5127</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: VHL</rdfs:comment>
        <rdfs:label>Von Hippel-Lindau Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005495"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007181</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide vaccine based on the sequences of a translocation mutation of 2 transcriptional factor genes, PAX3 and FKHR. PAX3/FKHR fusion proteins are frequently found in patients with rhabdomyosarcomas. Vaccination with PAX3/FKHR peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this PAX3/FKHR fusion protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C49023</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00001564</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:15838707</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5484</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/114</obo:IAO_0000233>
        <obo:OGG_0000000006>2308</obo:OGG_0000000006>
        <obo:OGG_0000000006>5077</obo:OGG_0000000006>
        <obo:OGG_0000000006>7422</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5484</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FOXO1</rdfs:comment>
        <rdfs:comment>Gene name: PAX3</rdfs:comment>
        <rdfs:comment>Gene name: VEGFA</rdfs:comment>
        <rdfs:label>PAX3/FKHR Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005495"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007182</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant retroviral virus derived from SR-A strain of Rous sarcoma virus carrying a constitutively active form of the AKT Gene. The viral vector RCAS harbors a Replication Competent ALV Splice acceptor. This recombinant virus was use in animal model to study gliomagenesis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29908</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5044</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/192</obo:IAO_0000233>
        <obo:OGG_0000000006>207</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5044</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: AKT1</rdfs:comment>
        <rdfs:label>RCAS-Akt Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007183 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007183">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005495"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007183</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant retroviral virus derived from SR-A strain of Rous sarcoma virus carrying a human gene encoding the G12D mutant form of K-Ras. The viral vector, RCAS harbors a Replication Competent ALV Splice acceptor. This recombinant virus was use in animal model to study gliomagenesis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C29910</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5500</obo:IAO_0000119>
        <obo:OGG_0000000006>3845</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5500</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KRAS</rdfs:comment>
        <rdfs:label>RCAS-Ras Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007184">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005495"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007184</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT). Telomerase expression has been directly linked to tumor development; its catalytic subunit is expressed in the majority of human cancer cells, but infrequently in normal cells. Vaccination with telomerase:540-548 peptide may stimulate cytotoxic T cells to recognize and kill telomerase-expressing cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Jimmy Guo</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Virginia He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C2640</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00069940</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:11536162</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5098</obo:IAO_0000119>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5098</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>telomerase: 540-548 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007185">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007185</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that may stimulate an immune response against 4 different melanoma associated antigens. This may lead to a reduction in tumor cell proliferation of cancer cells expressing these antigens. The vaccine may contain 4 class I MHC-restricted synthetic melanoma peptides (1 each restricted by HLA-A1, -A3, and two restricted by HLA-A2) and a helper tetanus peptide. The peptides may include Melan-A, gp100, MAGE-3, and NA17. The vaccine can be used in combination Ontak, which may produce an immune response in patients with metastatic melanoma, and the Ontak may improve these immune responses and lead to tumor shrinkage.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C91722</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00515528</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6370</obo:IAO_0000119>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6370</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGE-3</rdfs:comment>
        <rdfs:comment>Gene name: Melan-A</rdfs:comment>
        <rdfs:comment>Gene name: NA17</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>4-peptide melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007186 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007186</metadata:prefixIRI>
        <obo:IAO_0000115>To obtain SOCS1-silenced DCs, DCs derived from mouse bone marrow cells ex vivo were induced to differentiation in the presence of granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-4, and then transduced with Len-SOCS1-shRNA or control Len-GFP lentiviruses. The SOCS1-silenced DCs were loaded by TRP2 peptide to prepare the DC vaccine, which was induced to mature by LPS. The DCs were analyzed by flow cytometry (FCM) for surface expressions of MHCII and CD86 and by real-time PCR for the expressions of SOCS1, IL-10 as well as IL-12p40. B16 or IL-10-silenced B16 (IL-10(-/-);) cells were inoculated into C57BL/6 mice.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>1(SOCS1)-silenced dendritic cell (DC) Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:23643168</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4071</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/78</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4071</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>1(SOCS1)-silenced dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007187 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007187</metadata:prefixIRI>
        <obo:IAO_0000115>A fragment of fibroblast growth factor-5 (FGF-5). Originally isolated from a renal cell carcinoma cell line that overexpressed FGF-5, FGF-5:117-126 peptide is recognized by tumor infiltrating cytotoxic T lymphocytes. Overexpressed by several cancer cell types, this peptide is being tested as a potential target for antineoplastic immunotherapies. (NCI04)</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5414</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/79</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5414</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>117-126:FGF-5 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007188 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007188</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/80"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0007189"/>
        <rdfs:label>obsolete 12 Melanoma Peptide Vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007189 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007189</metadata:prefixIRI>
        <obo:IAO_0000115>Melonoma vaccine that uses 12 class I major histocompatibility complex-restricted melanoma peptides (12MP) from cancer-testis antigens (CTAs) and melanocytic differentiation proteins (MDPs).</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>12MP vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:21690475</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3978</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/81</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3978</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>12 melanoma peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007190 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007190">
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007190</metadata:prefixIRI>
        <obo:IAO_0000115>4 treatment groups, vaccinated with 12 MHC class I-restricted melanoma peptides to stimulate CTL (12 MP, group A), plus a tetanus peptide (group B), or a mixture of 6 melanoma helper peptides (6 MHP, group C) to stimulate helper T lymphocytes (HTL), or with 6 melanoma helper peptide (6 MHP) alone (group D), in incomplete Freund&apos;s adjuvant plus granulocyte macrophage colony-stimulating factor.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:23653149</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4070</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/82</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4070</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>12MP, 12MP/Tet, 12MP/6MHP, or 6MHP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007191 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007191</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide consisting of amino acids 27 through 35 of the melanoma differentiation antigen MART-1. 27-35(27L) MART-1 has a leucine substitution at amino acid position 27 to improve binding to HLA-A*0201. Vaccination with this agent may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against melanoma cells expressing MART-1.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22495394</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5290</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/83</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5290</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>27-35(27L):MART-1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007192">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007656"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007192</metadata:prefixIRI>
        <obo:IAO_0000115>A topical gel containing a peptide derived from the human papillomavirus (HPV). Application of 851B gel may stimulate the host immune system to trigger a cytotoxic T-lymphocyte response to cells that express HPV.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4986</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/84</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4986</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>851B Gel vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007193 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007193">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007193</metadata:prefixIRI>
        <obo:IAO_0000115>A murine IgG1 monoclonal anti-idiotype antibody, containing a variable antigen-binding region that functionally mimics the three-dimensional structure of a specific epitope on the ovarian cancer tumor-associated antigen CA-125, with potential antineoplastic activity. With a variable antigen-binding region that acts as a surrogate antigen for CA-125, abagovomab may stimulate the host immune system to elicit humoral and cellular immune responses against CA-125-positive tumor cells, resulting in inhibition of tumor cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Abagovomab</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:17000686</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5244</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/86</obo:IAO_0000233>
        <obo:OGG_0000000006>94025</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5244</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC16</rdfs:comment>
        <rdfs:label>Abagovomab vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007194">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007194</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:11860704</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5543</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/87</obo:IAO_0000233>
        <obo:OGG_0000000006>2875</obo:OGG_0000000006>
        <obo:OGG_0000000006>7124</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5543</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GPT</rdfs:comment>
        <rdfs:comment>Gene name: TNF</rdfs:comment>
        <rdfs:label>Ad CMV I kappaB alpha vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007195 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007195">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007195</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant adenoviral vector encoding the tumor-associated antigen (TAA) human MUC-1 (hMUC-1) linked to the extracellular domain (ecd) of the co-stimulatory molecule CD40 ligand (CD40L) and an adenovirus signal sequence that encodes a secretory signal peptide (Ad-sig) with potential immunostimulating and antineoplastic activities. Due to the presence of the secretory signal peptide expressed by Ad-sig in the vaccine construct, transfected cells may secrete a fusion protein composed of hMUC-1 and the CD40L ecd. The CD40L moiety part of the fusion protein binds to CD40 receptors on dendritic cells (DCs). Subsequently, DCs may be activated and migrate, T-cells may expand, and a cytotoxic T lymphocyte (CTL) response against tumor cells that overexpress hMUC-1 may follow. MUC-1 is a hypoglycosylated TAA overexpressed by epithelial cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5179</obo:IAO_0000119>
        <obo:IAO_0000119>https://ascopubs.org/doi/10.1200/JCO.2018.36.15_suppl.3098</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/88</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:OGG_0000000006>959</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5179</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40LG</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>Ad-sig-hMUC-1/ecdCD40L vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007196 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007196">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007196</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0007572"/>
        <rdfs:label>obsolete Ad5-yCD/mutTKSR39rep-hIL12 Vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007197 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007197">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007197</metadata:prefixIRI>
        <obo:IAO_0000115>A nonreplicating adenoviral vector (adenovector) encoding the melanoma differentiation-associated 7 gene (MDA7) with potential antineoplastic activity. After intratumoral injection and adenovector-mediated gene transfer of MDA7 into tumor cells, the expressed MDA7 transgene may inhibit tumor cell proliferation and induce tumor cell apoptosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15300212</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5523</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/92</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5523</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Adenovector Encoding MDA7 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007198 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007198</metadata:prefixIRI>
        <obo:IAO_0000115>A genetically-modified, dendritic cell-based (DCs) vaccine in which the autologous cells are transduced with an adenoviral vector expressing the tumor antigen prostate-specific membrane antigen (PSMA) and a fusion protein composed of synthetic ligand inducible adjuvant iMC composed of a drug-inducible costimulatory CD40 receptor (iCD40) and the adaptor protein MyD88, with potential immunomodulating and antineoplastic activities. The iCD40 contains a membrane-localized cytoplasmic CD40 domain fused to the FK506 modified drug-binding protein 12 (FKBP12). Upon intradermal administration of BPX-201, these DCs accumulate in local draining lymph nodes. Twenty-four hours after vaccination, the dimerizing agent AP1903 is administered. AP1903 binds to the drug binding domain, leading to iMC oligomerization and activation of iCD40 and MyD88-mediated signaling in iMC-expressing DCs. This signaling pathway activates the DCs and stimulates a cytotoxic T-lymphocyte (CTL) response against host tumor cells that express PSMA. PSMA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed in prostate cancer cells and is used as a tumor marker for both diagnosis and treatment evaluation. MyD88 is involved in interleukin 1 receptor (IL1R) and toll-like receptor (TLR) signaling.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4999</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/93</obo:IAO_0000233>
        <obo:OGG_0000000006>2346</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4999</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Prostate-specific membrane antigen</rdfs:comment>
        <rdfs:label>Adenovector-transduced AP1903-inducible MyD88/CD40-expressing Autologous PSMA-specific Prostate Cancer Vaccine BPX-201</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007199 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007199</metadata:prefixIRI>
        <obo:IAO_0000115>A replication-defective, E1- and E2b-deleted oncolytic adenoviral serotype 5 (Ad5) encoding an epitope of human carcinoembryonic antigen (CEA) with potential antineoplastic activity. Adenoviral vector Ad5-CEA(6D) vaccine expresses a highly immunogenic analogue of CEA [CAP1-(6D)]. Upon administration, this vaccine may induce both humoral and cellular immune responses against tumor cells expressing the CEA antigen, thereby resulting in the immune-mediated inhibition of tumor cell proliferation and tumor cell death. CEA, a tumor-associated antigen, is overexpressed in various tumor cell types. Deletion of early genes E1 and E2b in Ad5 potentially circumvent pre-existing anti-adenovirus immunity and is capable of inducing strong immune responses.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:25956394</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5137</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/94</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5137</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:label>Adenoviral Vector Ad5-CEA(6D) Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007200 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007200</metadata:prefixIRI>
        <obo:IAO_0000115>An adenovirus vector engineered to produce CD40 ligand. For use as a possible gene therapy agent. May induce apoptosis through the TNF pathway.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15153545</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5529</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/95</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001818>5529</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Adenovirus 5-CD40 Ligand Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007201 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007201</metadata:prefixIRI>
        <obo:IAO_0000115>Fibroblast growth factor-2-retargeted adenoviral vectors may be used to increase the transduction of GBM-derived endothelial cells, enabling a new and efficient antiangiogenesis strategy for the treatment of malignant gliomas.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16709032</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5489</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/96</obo:IAO_0000233>
        <obo:OGG_0000000006>2247</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001818>5489</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FGF2</rdfs:comment>
        <rdfs:label>Adenovirus 5-Fibroblast Growth Factor 2 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007202 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007202">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_3717"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007202</metadata:prefixIRI>
        <obo:IAO_0000115>A replication-defective, recombinant adenoviral serotype 5 (Ad5) encoding human guanylyl cyclase C (hGCC) and the synthetic Pan DR epitope (PADRE), with potential antineoplastic and immunomodulating activities. Upon intramuscular administration, the Ad5-hGCC-PADRE vaccine expresses hGCC, which may induce both humoral and cellular immune responses against tumor cells expressing the hGCC antigen. This results in the immune-mediated inhibition of tumor cell proliferation, and leads to tumor death. The hGCC protein is normally restricted to intestinal epithelial cells but is overexpressed by metastatic colorectal tumors. PADRE is a helper T-lymphocyte epitope that is able to augment the magnitude and duration of the cytotoxic T-lymphocyte (CTL) response.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT04111172</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5147</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/97</obo:IAO_0000233>
        <obo:OGG_0000000006>2984</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3717"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5147</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GUCY2C</rdfs:comment>
        <rdfs:label>Adenovirus 5-Human Guanylyl Cyclase C-PADRE vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007203 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007203">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007203</metadata:prefixIRI>
        <obo:IAO_0000115>A gene-viral vector complex comprised of an adenovirus vector and B7-1 gene targeting the CD80 antigen. Adenovirus B7-1 is used as a component in antineoplastic vaccines to elicit a cytotoxic T-cell response.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5435</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/98</obo:IAO_0000233>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5435</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:label>Adenovirus B7-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007204 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007204">
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            </owl:Restriction>
        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007204</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a recombinant adenoviral vector encoding HER-2/neu.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00307229</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5388</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/99</obo:IAO_0000233>
        <obo:OGG_0000000006>24337</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5388</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Erbb2</rdfs:comment>
        <rdfs:label>Adenovirus Encoding Rat HER-2/neu Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007205 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007205">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007205</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a recombinant adenoviral vector encoding three full length human melanoma associated antigens (MAAs), tyrosinase, melan-A (MART-1) and the melanoma antigen A6 (MAGEA6), with potential antineoplastic activity. Upon intradermal administration, adenovirus encoding tyrosinase/MART-1/MAGEA6-transduced autologous DC vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tyrosinase/MART-1/MAGEA6-positive tumor cells, which may result in tumor cell death and decreased tumor growth. Tyrosinase, a melanoma-specific differentiation antigen, catalyzes the first step of melanin synthesis in melanocytes. Vaccination with multi-antigen modified DC may improve the efficacy of the DC immunotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22737604</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5370</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/100</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>4105</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5370</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA6</rdfs:comment>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:label>Adenovirus Encoding Tyrosinase/MART-1/MAGEA6-transduced Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007206 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007206">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007206</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a replication-deficient adenovirus vector encoding HER-2 with potential antineoplastic activity. Upon administration, adenovirus HER2-transduced autologous dendritic cell vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against HER-2-positive tumor cells, which may result in tumor cell death and decreased tumor growth. HER-2, a tyrosine kinase receptor for epidermal growth factor (EGF) (also known as neu and ErbB2), is overexpressed by some breast, ovarian, and gastric cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00197522</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5082</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/101</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5082</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>Adenovirus HER2-Transduced Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007207 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007207">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007207</metadata:prefixIRI>
        <obo:IAO_0000115>A gene viral vector complex comprised of a replication-defective adenovirus and a herpes simplex virus thymidine kinase gene that activates ganciclovir, causing inhibition of DNA synthesis and apoptosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:/8985364</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5122</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/102</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5122</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Adenovirus RSV-TK vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007208 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007208">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007208</metadata:prefixIRI>
        <obo:IAO_0000115>A replication incompetent adenovirus encoding human pro-inflammatory cytokine interleukin-12 (IL-12) (Ad.hIL-12), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration, the adenovirus selectively infects and replicates in tumor cells, which may result in tumor cell lysis. Synergistically, IL-12 expressed by the adenovirus may activate the immune system by promoting the activation of natural killer cells (NKs), inducing secretion of interferon-gamma and inducing cytotoxic T cell responses against tumor cells, which may result in immune-mediated tumor cell death and inhibition of tumor cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:33575474</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5285</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/103</obo:IAO_0000233>
        <obo:OGG_0000000006>2346</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5285</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Prostate-specific membrane antigen gene engineering</rdfs:comment>
        <rdfs:label>Adenovirus-mediated Human Interleukin-12 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007209 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007209">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007209</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous dendritic cells (DCs) transduced with a recombinant adenovirus encoding p53 peptide, with potential immunomodulating activity. Intradermal vaccination with adenoviral-p53 transduced dendritic cell vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing mutant p53, resulting in tumor cell lysis. p53, a tumor suppressor gene, is mutated in many tumor cells, resulting in the loss of apoptosis regulation and abnormal cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:20420527</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:29515795</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5256</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/104</obo:IAO_0000233>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5256</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TP53 (P53)</rdfs:comment>
        <rdfs:label>Adenovirus-p53 transduced dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007210 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007210">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007210</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of a genetically engineered, replication-deficient type 5 adenovirus carrying the human prostate-specific antigen (PSA), with potential immunostimulating and antineoplastic activities. Upon subcutaneous vaccination with the adenovirus-PSA prostate cancer vaccine, the adenovirus infects cells and expresses PSA. In turn, PSA may activate the immune system and may induce a cytotoxic T-lymphocyte response against PSA-expressing tumor cells. PSA, a tumor associated antigen, is expressed by prostate epithelial cells and is overexpressed in prostate cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5010</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/105</obo:IAO_0000233>
        <obo:OGG_0000000006>2346</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5010</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Prostate-specific membrane antigen gene engineering</rdfs:comment>
        <rdfs:label>Adenovirus-PSA Prostate Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007211 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007211">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007211</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based vaccine comprised of prostate cancer cells transduced with an adenoviral vector encoding human RTVP-1 (AdRTVP-1), with potential antineoplastic and immunostimulating activities. RTVP-1, also referred to as glioma pathogenesis-related protein 1 (GLIP1), is down-regulated in prostate tumors. Regulated by tumor suppressor p53, the expression of RTVP-1 functions as a tumor suppressor, and is abundant in normal human prostate epithelial cells as well as in differentiated macrophages. Administration of this vaccine leads to an induction of apoptosis through the expression of RTVP-1 and results in a reduction in cellular proliferation in prostate cancer cells. In addition, this cancer-cell based vaccine may induce a cytotoxic T lymphocyte (CTL) response against prostate specific tumor associated antigens, resulting in an immune-mediated prostate cancer cell death. Furthermore, RTVP-1 stimulates CTL and natural killer (NK) cell activities.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5203</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/106</obo:IAO_0000233>
        <obo:OGG_0000000006>11010</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5203</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GLIPR1</rdfs:comment>
        <rdfs:label>AdRTVP-1-Transduced Prostate Cancer Cell-Based Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007212 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007212">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007212</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine containing HER2/Neu-derived epitope (amino acids 776-790) linked to li-Key peptide (li-Key/HER2/neu hybrid peptide or AE37), and combined with granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential antineoplastic and immunoadjuvant activities. Upon vaccination, AE37 may activate the immune system and stimulate T-helper cells against HER2/Neu expressing cancer cells. GM-CSF may potentiate the immune response against cancer cells expressing the HER2/Neu antigen. The Ii-Key moiety, a 4-amino acid (LRMK) epitope from the MHC class II-associated invariant chain (Ii protein), increases T-helper cell stimulation against HER2/neu antigen when compared to unmodified class II epitopes. HER2/neu, a tumor associated antigen (TAA), is overexpressed in a variety of tumor cell types and is highly immunogenic.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:32323103</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5436</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/107</obo:IAO_0000233>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5436</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:label>AE37 Peptide/GM-CSF Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007213 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007213">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005429"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007213</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of naked plasmid DNA of the gene for the tumor-associated antigen alpha-fetoprotein (AFP), a macromolecule that acts as a specific immunologic target for hepatocellular carcinoma. This agent exerts an antitumor effect by inducing cytotoxic T-lymphocytes to attack AFP-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5275</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/108</obo:IAO_0000233>
        <obo:OGG_0000000006>174</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5275</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: AFP</rdfs:comment>
        <rdfs:label>AFP Gene Hepatocellular Carcinoma Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007214 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007214">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007214</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made of a recombinant NY-ESO-1 protein with a TLR7 agonist</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:C5941317</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3991</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/109</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3991</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>Ag NY-ESO-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007215 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007215">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007215</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing the three frame shift peptides (FSP) AIM2(-1), HT001(-1) and TAF1B(-1), with potential immunomodulating activity. Upon administration, the AIM2(-1)/HT001(-1)/TAF1B(-1) FSP vaccine may induce an immune response against microsatellite instability (MSI) colorectal cancer-associated antigens. Frame shift mutations of AIM2 (absent in melanoma 2, an interferon-inducible protein), HT001 (asteroid homolog 1 or ASTE1, with an unknown function) and TAF1B (TATA box-binding protein-associated RNA polymerase I B, a transcription factor) are seen in MSI-positive colorectal cancers and may be associated with malignant transformation, tumor progression and the presence of tumor-infiltrating lymphocytes. These FSPs all have one-base deletions.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01461148</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5402</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/110</obo:IAO_0000233>
        <obo:OGG_0000000006>28990</obo:OGG_0000000006>
        <obo:OGG_0000000006>9014</obo:OGG_0000000006>
        <obo:OGG_0000000006>9447</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5402</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: AIM2</rdfs:comment>
        <rdfs:comment>Gene name: ASTE1</rdfs:comment>
        <rdfs:comment>Gene name: TAF1B</rdfs:comment>
        <rdfs:label>AIM2(-1)/HT001(-1)/TAF1B(-1) Frameshift Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007216 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007216">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007216</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of irradiated allogeneic pancreatic cancer cells transfected to express murine alpha-1,3-galactosyltransferase with potential antitumor activity. Vaccination is associated with the expression of murine alpha-1,3-galactosyl (alpha-gal) carbohydrate residues on cell membrane glycoproteins and glycolipids of the vaccine pancreatic cancer cell allograft; murine alpha-gal epitopes, not present on human cells, then induce a hyperacute rejection of the vaccine pancreatic cancer cell allograft. The hyperacute rejection involves the binding of pre-existing human anti-alpha-gal antibodies (which naturally occur against gut flora) to murine alpha-gal epitopes, resulting in the rapid activation of antibody-dependent cell-mediated cytotoxicity (ADCC) towards allograft cells. The host immune system then attacks endogenous pancreatic cancer cells, resulting in ADCC towards endogenous pancreatic cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26787078</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5422</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/145</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:OGG_0000000006>111518</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5422</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>CEA</rdfs:comment>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:label>Algenpantucel-L Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007217 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007217">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005487"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007217</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of allogeneic, immortalized dendritic precursor cells derived from a patient with acute myelogenous leukemia (AML), with potential immunostimulatory and antineoplastic activities. Upon ex vivo stimulation and expansion of the precursor cells into mature, fully functional dendritic cells (DCs) and subsequent administration, the allogeneic AML antigen-expressing DC vaccine may elicit a potent cytotoxic T-cell (CTL) and antibody response against AML antigen-expressing cells, resulting in tumor cell death.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5020</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/146</obo:IAO_0000233>
        <obo:OGG_0000000006>5788</obo:OGG_0000000006>
        <obo:OGG_0000000006>945</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5020</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD33</rdfs:comment>
        <rdfs:comment>Gene name: PTPRC</rdfs:comment>
        <rdfs:label>Allogeneic AML Antigen-expressing Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007218 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007218">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007218</metadata:prefixIRI>
        <obo:IAO_0000115>An allogeneic whole cell vaccine, derived from irradiated allogenic tumor cells manipulated to express human B7.1 (CD80 antigen) and human leukocyte antigen (HLA) A1, with potential antitumor activity. Vaccination with allogeneic B7.1/HLA-A1 transfected tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15254047</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4998</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/147</obo:IAO_0000233>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4998</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:label>Allogeneic B7.1/HLA-A1 Transfected Tumor Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007219 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007219">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007219</metadata:prefixIRI>
        <obo:IAO_0000115>A pluripotent, allogeneic, tumor cell vaccine composed of irradiated tumor cells from the non-small cell lung cancer (NSCLC) cell line 1650 and the immunoadjuvant recombinant granulocyte-macrophage colony stimulating factor (GM-CSF) (1650-G), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic cellular vaccine 1650-G may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against tumor-associated antigens (TAAs) expressed on NSCLC cells. GM-CSF potentiates the antitumor immune response. The 1650 cell line is used as a source for TAAs.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5257</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/148</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:OGG_0000000006>4101</obo:OGG_0000000006>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5257</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA2</rdfs:comment>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>Allogeneic Cellular Vaccine 1650-G</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007220 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007220">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007220</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of allogeneic, immortalized dendritic cells (DCs) loaded with tumor specific antigens and activated, with potential immunostimulatory and antineoplastic activities. Upon intratumoral administration of the allogeneic dendritic cell vaccine COMBIG-DC, these activated DCs attract natural killer (NK) cells, induce an anti-inflammatory response leading to the induction of NK-cell-mediated tumor cell death. Upon release of tumor associated antigens (TAAs) from the lysed tumor cells, these antigens are taken up by antigen presenting cells which activate the immune system to elicit a potent cytotoxic T-cell (CTL) response against the TAAs, resulting in the death of TAAs-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01525017</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01974661</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5446</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/149</obo:IAO_0000233>
        <obo:OGG_0000000006>3458</obo:OGG_0000000006>
        <obo:OGG_0000000006>7124</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5446</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IFNG</rdfs:comment>
        <rdfs:comment>Gene name: TNF</rdfs:comment>
        <rdfs:label>allogeneic dendritic cell vaccine COMBIG-DC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007221 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007221">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005492"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007221</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based vaccine composed of allogeneic dendritic cells pulsed ex-vivo with an autologous myeloma idiotype with potential antineoplastic activity. Upon administration, allogeneic dendritic cell-myeloma idiotype vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against myeloma cells, resulting in cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5102</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/150</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5102</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Allogeneic Dendritic Cell-Myeloma Idiotype Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007222 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007222</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from an allogeneic glioblastoma (GBM) stem-like cell line, with potential immunostimulatory and antineoplastic activities. Upon administration allogeneic glioblastoma stem-like cell line lysate-pulsed autologous dendritic cell vaccine exposes the immune system to GBM stem cell antigens, which may result in cytotoxic T lymphocyte (CTL) and antibody responses against GBM cells. This leads to GBM cell lysis. GBM stem-like cells contain a specific range of antigens that are essential for the neoplastic growth and survival of GBM cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5023</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/151</obo:IAO_0000233>
        <obo:OGG_0000000006>7070</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5023</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD90</rdfs:comment>
        <rdfs:label>Allogeneic Glioblastoma Stem-like Cell Line Lysate-pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007223 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007223</metadata:prefixIRI>
        <obo:IAO_0000115>An allogeneic tumor cell vaccine containing myeloma cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Upon vaccination, allogeneic GM-CSF-based myeloma cellular vaccine secretes GM-CSF, which may potentiate a tumor-specific cytotoxic T-lymphocyte (CTL) response against myeloma cancer cell-associated antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5327</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/152</obo:IAO_0000233>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:OGG_0000000006>9947</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5327</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-SCF</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:comment>Gene name: MAGEC1</rdfs:comment>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>Allogeneic GM-CSF-Based Myeloma Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007224">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007224</metadata:prefixIRI>
        <obo:IAO_0000115>An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon vaccination, the genetically modified cells secrete GM-CSF, thereby potentiating a tumor-specific T cell response against breast cancer cell-asociated antigens.A vaccine that is being studied as a way to help the body&apos;s immune system kill breast cancer cells. To make the vaccine, the GM-CSF gene is put into breast cancer cells in the laboratory. The cells are then treated with radiation to stop them from growing and injected into the same or a different patient. The GM-CSF protein made by the changed breast cancer cells may help the immune system kill breast cancer cells in the body.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5059</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/153</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5059</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>Allogeneic GM-CSF-Secreting Breast Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007225 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007225">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007225</metadata:prefixIRI>
        <obo:IAO_0000115>An allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with a plasmid carrying the gene for cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Allogeneic GM-CSF-secreting tumor vaccine PANC 10.05 pcDNA-1/GM-Neo secretes GM-CSF thereby activating dendritic cells, promoting antigen presentation to B- and T-cells, and promoting a cytotoxic T-lymphocyte (CTL) response. This may eventually kill tumor cells. The pancreatic tumor cells are derived from the PANC 10.05 tumor cell line.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01088789</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5075</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/154</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5075</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Allogeneic GM-CSF-secreting Tumor Vaccine PANC 10.05 pcDNA-1/GM-Neo</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007226 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007226">
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        <rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007226</metadata:prefixIRI>
        <obo:IAO_0000115>An allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with a plasmid carrying the gene for cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Allogeneic GM-CSF-secreting tumor vaccine PANC 6.03 pcDNA-1/GM-Neo secretes GM-CSF thereby activating dendritic cells, promoting antigen presentation to B- and T-cells, and promoting a cytotoxic T-lymphocyte (CTL) response. This may eventually kill tumor cells. The pancreatic tumor cells are derived from the PANC 6.03 tumor cell line.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5515</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2010-01868&amp;r=1</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/155</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5515</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Allogeneic GM-CSF-secreting Tumor Vaccine PANC 6.03 pcDNA-1/GM-Neo</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007227 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007227</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine, containing human-specific large multivalent immunogens (LMIs) isolated from the membrane fraction of cells from a breast cancer cell line, with potential immunostimulatory and antineoplastic activities. Upon administration, allogeneic large multivalent immunogen breast cancer vaccine may stimulate a cytotoxic T lymphocyte (CTL) immune response against tumor cells that express the breast cancer cell-specific LMIs.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5269</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/156</obo:IAO_0000233>
        <obo:OGG_0000000006>1493</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5269</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTLA4</rdfs:comment>
        <rdfs:label>Allogeneic Large Multivalent Immunogen Breast Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007228 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007228</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine, containing human-specific large multivalent immunogen (LMI) isolated from plasma membrane fractions of the melanoma cell lines MSM-M1 and MSM-M2, with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic large multivalent immunogen melanoma vaccine LP2307 may stimulate a CD8+ cytotoxic T lymphocyte (CTL) response against melanoma tumor cells that express melanoma-specific LMI.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00726739</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5423</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/157</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5423</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>Allogeneic Large Multivalent Immunogen Melanoma Vaccine LP2307</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007229">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007229</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine derived from two gentically modified human melanoma cell lines with potential antineoplastic activity. Allogeneic melanoma vaccine AGI-101H consists of a 1:1 mixture of cells from two genetically modified human melanoma cell lines, designated as Mich1H6 and Mich2H6, that have been gamma-irradiated to render the cells non-proliferative. Upon administration, this vaccine may stimulate a cytotoxic immune response against melanoma tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:32002306</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5376</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/158</obo:IAO_0000233>
        <obo:OGG_0000000006>216</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5376</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ALDH1A1</rdfs:comment>
        <rdfs:label>Allogeneic Melanoma Vaccine AGI-101H</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007230 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007230">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005491"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007230</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with a mixture of lysates from five allogeneic mesothelioma tumor cell lines, with potential immunostimulatory and antineoplastic activities. Upon leukapheresis, DCs are loaded with allogeneic mesothelioma tumor cell lysates. Upon re-administration of the allogeneic mesothelioma tumor lysate-pulsed autologous DC vaccine, the immune system is exposed to an undefined amount of mesothelioma-associated antigens, which stimulates the induction of a specific cytotoxic T-lymphocyte (CTL) response against mesothelioma tumor cells and leads to tumor cell lysis</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5440</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/159</obo:IAO_0000233>
        <obo:OGG_0000000006>10232</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/MONDO_0005065"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5440</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MSLN</rdfs:comment>
        <rdfs:label>Allogeneic Mesothelioma Tumor Lysate-pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007231 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007231">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007231</metadata:prefixIRI>
        <obo:IAO_0000115>A biologic product that consists of undifferentiated stem cells, obtained from adult bone marrow or other non-embryonic tissue sources, that are expanded in vitro and deposited in master cell banks for &quot;&quot;off-the-shelf&quot;&quot; use, with potential hematopoiesis-inducing and immunomodulating activities. Allogeneic multipotent adult progenitor cells (MAPCs) are non-immunogenic due to the lack of major histocompatibility (MHC) molecule expression, and so elicit no immune response upon administration. In vivo, bone marrow-derived adult stem cells are capable of maturing into a broad range of cell types and may help restore the immune system by producing multiple therapeutic molecules in response to inflammation and tissue damage.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5054</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/160</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5054</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>allogeneic multipotent adult progenitor cells vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007232">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007232</metadata:prefixIRI>
        <obo:IAO_0000115>A whole cell vaccine comprised of irradiated allogeneic renal cell carcinoma (RCC) with potential immunostimulating and antineoplastic activities. Allogeneic renal cell carcinoma vaccine MGN1601 contains two active ingredients: 1) genetically modified allogeneic RCC cells that are transiently transfected with four different MIDGE (Minimalistic Immunogenically Defined Gene Expression) vectors encoding IL-7, GM-CSF, CD80 and CD154 and 2) the synthetic DNA-based immunomodulator dSLIM-30L1, a TLR9 agonist.. Vaccination results in expression of IL-7, GM-CSF, CD80 and CD154, which all contribute to the activation or enhancement of immune responses. Furthermore, administration of this RCC vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor growth. TLR9 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5358</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)36654-0</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/161</obo:IAO_0000233>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:OGG_0000000006>959</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5358</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40LG</rdfs:comment>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:label>Allogeneic Renal Cell Carcinoma Vaccine MGN1601</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007233 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007233">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005492"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007233</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine composed of tumor cells isolated from the tumor of one patient, killed and processed, and administered to another patient to stimulate cytotoxic immune responses to a similar tumor cell type. The cells found in this type of whole-cell vaccine express many cell-surface tumor-associated antigens. This vaccine is frequently administered with an adjuvant immunostimulant.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5339</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/allogeneic-tumor-cell-vaccine</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/162</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5339</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>allogeneic tumor cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007234 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007234</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine composed of killed glioma cancer cells from another patient for use in immunotherapy</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24829761</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5119</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/163</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5119</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Allogenic Glioma Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007235 -->

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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007235</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of a recombinant adenoviral vector encoding alpha fetoprotein. After vaccination, expressed alpha fetoprotein may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells that express alpha fetoprotein, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:25041030</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5313</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/164</obo:IAO_0000233>
        <obo:OGG_0000000006>149</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5313</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: AFP</rdfs:comment>
        <rdfs:label>Alpha Fetoprotein Adenoviral Vector Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007236">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007236</metadata:prefixIRI>
        <obo:IAO_0000115>An allogeneic renal cell cancer (RCC) vaccine composed of cell line-derived RCCs that are genetically engineered to express the murine alpha-1,3-galactosyltransferase (GalT), with potential immunostimulatory and antineoplastic activities. Not naturally occurring in humans, GalT catalyzes the expression of foreign alpha-1,3-galactosyl (alpha-gal) carbohydrate epitopes on the cell membranes of the allogeneic RCCs present in the vaccine. This induces a hyperacute rejection reaction involving pre-existing human anti-alpha-gal antibodies, which bind to the foreign alpha-gal epitopes expressed by the allogeneic RCCs. This results in complement-mediated cytotoxicity (CMC) and antibody-dependent cell-mediated cytotoxicity (ADCC) towards endogenous RCCs with unmodified carbohydrate epitopes.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5349</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/165</obo:IAO_0000233>
        <obo:OGG_0000000006>11605</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5349</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Gla</rdfs:comment>
        <rdfs:label>Alpha-1,3-galactosyltransferase-expressing Allogeneic Renal Cell Carcinoma Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007237 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007237">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005429"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007237</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with four alpha-fetoprotein (AFP) peptides, with potential immunostimulatory and antineoplastic activities. Upon administration, AFP peptide-pulsed autologous dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against AFP-expressing cancer cells, resulting in tumor cell lysis. AFP is overexpressed in a variety of cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16675576</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5315</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/166</obo:IAO_0000233>
        <obo:OGG_0000000006>174</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5315</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: AFP</rdfs:comment>
        <rdfs:label>Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007238 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007238">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007238</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with the marine sponge glycolipid alpha-galactosylceramide (alpha-GalCer) with potential immunostimulatory and antimetastatic activities. Upon administration, alpha-galactosylceramide-pulsed autologous dendritic cells may result in the activation and proliferation of a subset of endogenous natural killer T (NKT) cells, B cells, and CD4+ and CD8+ T cells, and the production of interferon-gamma and interleukin-12; these cascade events may result in a T helper-1 cell-biased proinflammatory antitumor immune response. The NKT cell ligand alpha-GalCer was originally isolated from the marine sponge Agelas mauritianusis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:32188702</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5288</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/167</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5288</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Alpha-Galactosylceramide-Pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007239 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007239">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007239</metadata:prefixIRI>
        <obo:IAO_0000115>A mature polarized dendritic cell with potent immunostimulating activity. Treating dendritic cells (DCs) with interferon-alpha (IFN-a) and polyinosinic:polycytidylic acid (p-I:C) in addition to a cytokine cocktail (tumor necrosis factor alpha/Interleukin-1beta/IFN-gamma) produces mature but not exhausted alpha type-1 polarized DCs (alphaDC1) that are capable of: 1) high responsiveness to other lymphoid chemokines, and 2) producing high level of interleukin-12p70 (IL-12p70). Therefore, alphaDC1 has a much more significant capability of inducing helper T cell (CD4+ T-cell) responses in comparison with the &quot;&quot;gold standard&quot;&quot; DCs. When pulsed with specific tumor associated antigens (TAAs), alphaDC1 is able to induce a potent cytotoxic T lymphocyte (CTL) response against TAAs; as a result it can be used as a cancer vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5198</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/alpha-type-1-polarized-dendritic-cells</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/168</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1964"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5198</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>Alpha-type-1 polarized dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007240 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007240">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007240</metadata:prefixIRI>
        <obo:IAO_0000115>A derivative of the Canarypox Virus, ALVAC can infect mammalian cells but it can&apos;t replicate. Thus, it produces a self-limiting infection which does not produce symptoms or harm the host. When carrying foreign genes it will cause transient expression of protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:16061912</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5334</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/169</obo:IAO_0000233>
        <obo:OGG_0000000006>3458</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5334</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IFNG -Obselete </rdfs:comment>
        <rdfs:label>ALVAC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007241</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus. ALVAC-B7-CEA expresses carcinoembryonic antigen (CEA), a protein that is overexpressed by many tumor cells, and B7.1 (also known as CD80), the natural ligand for the T-cell antigen CD28, to augment the host immune response. This agent has been shown to stimulate a host immune response against tumor cells that express CEA. (NCI04)</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:12596363</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5444</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/210</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5444</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>ALVAC-B7-CEA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007242</metadata:prefixIRI>
        <obo:IAO_0000115>A replication-defective recombinant canarypox virus (ALVAC) that contains the entire human carcinoembryonic antigen (CEA) gene. Vaccination with ALVAC-CEA (VCP248) may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against CEA-positive tumor cells, thereby decreasing tumor growth. (NCI04)</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5003</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/212</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5003</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>ALVAC-CEA (VCP248) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007243 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007243">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007243</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that uses a viral vector system derived from the canarypox virus engineered to target the carcinoembryonic antigen (CEA). It causes infected cells to temporarily display CEA and activates the immune system to attack the tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:18676757</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5125</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/213</obo:IAO_0000233>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5125</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:label>ALVAC-CEA B7.1 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007244</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus, encoding for the tumor associated antigen (TAA) carcinoembryonic antigen (CEA), with potential antineoplastic activity. Upon administration, ALVAC-CEA vaccine expresses CEA and may stimulate a host immune response against tumor cells expressing CEA. This may result in the inhibition of tumor growth and/or metastasis. CEA is overexpressed in a variety of tumor cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5051</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/214</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5051</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>ALVAC-CEA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007245">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007245</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) encoding the cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon administration, ALVAC-ESO-1 vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against NY-ESO-1-expressing cancer cells, which may result in the inhibition of tumor cell proliferation. NY-ESO-1, a tumor associated antigen (TAA), is found in normal testis and on the surface of various tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01982487</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5332</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/215</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5332</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>ALVAC-ESO-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007246 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007246</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine comprise of a canarypox viral vector that carries the gene for human B7.1 (CD80 antigen) with potential use as an autologous therapeutic cancer vaccine. Tumor cells harvested from a patient are infected with ALVAC-hB7 1, thereby producing an autologous cell line that exhibits increased expression of HLA class I and class II, CD54 (ICAM), and CD80. Increased expression of these proteins by this autologous cell line may activate an antitumor T-cell response when the modified cells are administered to the patient.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00003556</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5181</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/216</obo:IAO_0000233>
        <obo:OGG_0000000006>1493</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5181</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTLA4</rdfs:comment>
        <rdfs:label>ALVAC-hB7.1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007247 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007247">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007247</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing a replication-defective recombinant canarypox virus (ALVAC), encoding an epitope of MART-1 (melanoma antigen recognized by T-cells), with potential immunostimulatory and antineoplastic activities. Upon administration, the MART-1 epitope is expressed by the ALVAC vector in ALVAC-MART-1 vaccine; a host cytotoxic T lymphocyte (CTL) response against MART-1-expressing tumor cells may follow, resulting in tumor cell lysis and decreased tumor cell proliferation</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00612222</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5124</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/217</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5124</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:label>ALVAC-MART-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007248 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007248">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007248</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine used to treat patients with malignant melanoma. It is made of a compatible melanoma cell line that has been engineered to express a molecule termed 4-1BBL, which enhances the chances of the cell line to be recognized by the patient&apos;s immune system, and to induce its stimulation, with an immune response to residual tumor in the body. It will be used in combination with intravenous low dose cyclophosphamide, 300 mg/m2.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01898039</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6260</obo:IAO_0000119>
        <obo:OGG_0000000006>8744</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6260</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: 4-1BBL</rdfs:comment>
        <rdfs:label>a2/4-1bbl melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007249 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007249">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007249</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic cancer vaccine, based on a replication-defective recombinant canarypox virus (ALVAC) encoding multiple melanoma antigens, with potential immunostimulatory and antineoplastic activities. Vaccination with ALVAC(2) melanoma multi-antigen therapeutic vaccine may stimulate the host immune system to mount an immune response against antigen-expressing melanoma cells, resulting in inhibition of tumor growth and/or metastasis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5394</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/170</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5394</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>ALVAC(2) Melanoma multi-antigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007250">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007250</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a replication-defective recombinant canarypox virus [ALVAC(2)] encoding the cancer-testis antigen NY-ESO and the TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; also called TRICOM), with potential immunostimulatory and antineoplastic activities. Upon administration, ALVAC(2)/NY-ESO (M)/TRICOM vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against NY-ESO-expressing cancer cells, which may result in the inhibition of tumor cell proliferation. NY-ESO-1, a tumor associated antigen (TAA), is found in normal testis and on the surface of various tumor cells, including bladder, breast, hepatocellular, melanoma, and prostate tumor cells. TRICOM may enhance antigen presentation and activate cytotoxic T-cells. In addition, ALVAC(2) encodes the vaccinia virus (vv) E3L ad K3L genes, which may potentiate the translation of the NY-ESO and TRICOM genes.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01982487</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5268</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/171</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>3383</obo:OGG_0000000006>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:OGG_0000000006>965</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5268</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD58</rdfs:comment>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:comment>Gene name: ICAM1</rdfs:comment>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>ALVAC(2)-NY-ESO-1 (M)/TRICOM vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007251 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007251">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005487"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007251</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous dendritic cells loaded with separate preparations of acute myelogenous leukemia (AML) cell lysate and AML-specific messenger RNA (mRNA) with potential immunostimulatory and antineoplastic activities. Upon administration, AML mRNA plus lysate loaded autologous dendritic cell vaccine may elicit a potent cytotoxic T-cell (CTL) response against AML cells, resulting in tumor cell death. Autologous dendritic cells doubly-loaded with AML cell lysate and AML-specific mRNA may elicit superior primary, recall, and effector lytic immune responses compared to autologous dendritic cells loaded with tumor lysate or tumor mRNA alone.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5533</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/219</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5533</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>AML mRNA Positive Lysate Loaded Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007252 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007252">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005488"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007252</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA-based vaccine consisting of small biodegradable poly(lactide-co-glicolide) polymer microparticles encapsulating plasmid-DNA vector encoding a chimeric protein comprising epitopes derived from the E6 and E7 oncoproteins of the human papillomavirus (HPV) types 16 and 18, with potential antineoplastic activity. Upon intramuscular vaccination, amolimogene bepiplasmid may elicit the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV-16 and -18 E6 and E7 and may result in a reduction in tumor cell growth. HPV types 16 and 18 oncoproteins E6 and E7 are most commonly involved in cervical cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:19051140</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5243</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/220</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5243</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>Amolimogene Bepiplasmid Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007253 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007253">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007253</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing pTVG4 plasmid DNA encoding the human androgen receptor (AR) ligand-binding domain (LBD) (pTVG-AR), with potential immunostimulating and antineoplastic activities. Upon intradermal administration of AR LBD-encoding plasmid DNA vaccine MVI-118, the plasmid DNA vaccine expresses AR LBD and may stimulate the host immune system to generate a cytotoxic T-lymphocyte (CTL) response against AR LBD-expressing prostate cancer cells. This reduces proliferation of AR-expressing tumor cells. AR, a tumor-associated antigen (TAA) overexpressed in prostate cancer cells, plays a key role in the development and progression of prostate cancer; its expression is correlated with poor prognosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:32513836</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5331</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/221</obo:IAO_0000233>
        <obo:OGG_0000000006>367</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5331</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: AR</rdfs:comment>
        <rdfs:label>Androgen Receptor Ligand-binding Domain-encoding Plasmid DNA Vaccine MVI-118</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007254 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007254">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007254</metadata:prefixIRI>
        <obo:IAO_0000115>A modified vaccinia Ankara (MVA) encoding 7 melanoma tumor antigen cytotoxic T lymphocyte (CTL) epitopes.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15627214</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3994</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/222</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3994</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Ankara (MVA) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007255</metadata:prefixIRI>
        <obo:IAO_0000115>Recombinant MVA-gp100M and ALVAC(2)-5T4 were constructed to complement existing ALVAC(2)-gp100M and MVA-5T4 vectors. Recombinant TAA expression in chicken embryo fibroblast cells was confirmed by Western blot analysis. 5T4 expression was approximately equal for both viruses, whereas ALVAC-derived gp100 was quickly degraded, at a time point when MVA-derived gp100 was still stable and expressed at high levels</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15627214</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4073</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/223</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4073</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Ankara (MVA) and ALVAC(2) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007256 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007256">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007256</metadata:prefixIRI>
        <obo:IAO_0000115>An anti-CD19/anti-CD3 bispecific tetravalent antibody with potential immunostimulatory and antineoplastic activities. Anti-CD19/CD3 tetravalent antibody AFM11 possesses two antigen-recognition and binding sites, one for the CD3 complex, a group of T-cell surface glycoproteins that complex with the T-cell receptor (TCR), and one for CD19, a tumor-associated antigen (TAA) overexpressed on the surface of B-cells. Upon bolus infusion of AFM11, this bispecific antibody binds to CD3-expressing T-cells and CD19-expressing cancer cells, thereby crosslinking CD19-expressing tumor B-cells and cytotoxic T-lymphocytes (CTLs). This may result in a potent CTL-mediated cell lysis of CD19-expressing B-lymphocytes. CD19, a B-cell specific membrane antigen, is expressed during both B-cell development and B-cell malignant growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5199</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/224</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5199</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Anti-CD19/CD3 Tetravalent Antibody AFM11 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007257 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007257">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007257</metadata:prefixIRI>
        <obo:IAO_0000115>Autologous activated T cells that have been coated with bispecific antibodies (BiAb), with potential antineoplastic and immunomodulating activities. In vitro, T cells are activated through exposure to the anti-CD3 murine monoclonal antibody OKT3 and low-dose interleukin 2 (Il-2) for 6-14 days and then armed with anti-CD3 x anti-CD20 bispecific antibody (CD20Bi). Upon administration, anti-CD3 x anti-CD20 bispecific antibody-armed activated T cells (AATC) attach to CD3-expressing T cells and CD20-expressing tumor cells, selectively cross-linking T cells and tumor cells. This may result in the recruitment and activation of cytotoxic T lymphocyte (CTLs), CTL-mediated specific tumor cell lysis, and the secretion of antitumor cytokines and chemokines. CD20, a cell surface phosphoprotein, is found on normal B cells and most B-cell tumors.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5411</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.targetedonc.com/view/cd20-cd3-bispecific-antibodies-can-revolutionize-b-cell-lymphoma-therapy</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/225</obo:IAO_0000233>
        <obo:OGG_0000000006>931</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5411</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MS4A1</rdfs:comment>
        <rdfs:label>Anti-CD3 x Anti-CD20 Bispecific Antibody-Armed Activated T Cells Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007258 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007258</metadata:prefixIRI>
        <obo:IAO_0000115>Autologous human peripheral blood lymphocytes (PBLs), transduced with a retroviral vector encoding both the alpha and beta chains of a T cell receptor (TCR) specific for the carcinoembryonic antigen (CEA), with potential immunostimulating and antineoplastic activities. After transduction, expansion in culture, and reintroduction into the patient, anti-CEA TCR retroviral vector-transduced autologous lymphocytes bind to tumor cells expressing CEA, which may result in cytokine expression, activation and proliferation of T-cells, and a specific cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells. The tumor-associated antigen (TAA) CEA is overexpressed by a variety of cancer cell types, including those of the gastrointestinal tract, lung, and breast.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Anti-CEA TCR Retroviral Vector-Transduced Autologous Peripheral Blood Lymphocytes</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5536</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/226</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5536</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>anti-CEA TCR retroviral vector-transduced autologous peripheral blood lymphocyte vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007259 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007259</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. Anti-CTLA4 MoAb RNA-transfected autologous DC vaccine is prepared by transfecting DCs with RNAs encoding humanized heavy and light chains of the anti-CTLA4 (cytotoxic T-Lymphocyte-Associated Antigen 4); expression of anti-CTLA4 blocks the inhibitory effect of CTLA4 on the activation of T-lymphocytes. Co-vaccination of this vaccine with melanoma antigen specific vaccine may eliminate the adverse effects associated with systemic administration of immune modulators, while also enhancing vaccine-induced immune responses</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5375</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/227</obo:IAO_0000233>
        <obo:OGG_0000000006>1493</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5375</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTLA4</rdfs:comment>
        <rdfs:label>anti-CTLA4 MoAb RNA-transfected autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007260 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007260</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. Anti-CTLA4 MoAb RNA/GITRL RNA-transfected DC vaccine is prepared by transfecting DCs with RNAs encoding humanized heavy and light chains of the anti-CTLA4 (cytotoxic T-Lymphocyte-Associated Antigen 4) monoclonal antibody and tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18 or GlTRL); expression of anti-CTLA4 blocks the inhibitory effect of CTLA4 on the activation of T-lymphocytes, while expression of GlTRL modulates T lymphocyte survival in peripheral tissues. Co-vaccination of this vaccine with melanoma antigen specific vaccine may eliminate the adverse effects associated with systemic administration of immune modulators, while also enhancing vaccine-induced immune responses.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5149</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/228</obo:IAO_0000233>
        <obo:OGG_0000000006>1493</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5149</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTLA4</rdfs:comment>
        <rdfs:label>anti-CTLA4 MoAb RNA/GITRL RNA-transfected autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007261">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007261</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine derived from the synthetic peptide pyroEHWSYGLRPG, corresponding to amino acids 22-31 of mouse gonadotropin releasing hormone (GnRH), with potential immunocastration activity. PEP223 is dimerized and contains a D-lysine (k) substitution at position 6 (pyroEHWSYkLRPG) to increase its immunogenicity. Anti-GnRH vaccine PEP223 may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against GnRH, neutralizing its activity. In turn, testosterone production and tumor cell growth may be inhibited in testosterone-sensitive tumors.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00895466</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5405</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/229</obo:IAO_0000233>
        <obo:OGG_0000000006>14714</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5405</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Gnhr1</rdfs:comment>
        <rdfs:label>Anti-GnRH Vaccine PEP223</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007262 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007262</metadata:prefixIRI>
        <obo:IAO_0000115>A monoclonal antibody that functionally mimics MUC-1 antigen, a tumor cell surface antigen. Administration of anti-idiotype MUC-1 monoclonal antibody may elicit an anti-idiotype antibody and corresponding T-cell response against MUC-1 expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15550589</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5175</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/230</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5175</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>anti-idiotype MUC-1 monoclonal antibody vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007263 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007263">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007263</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic antibody produced by a genetically homogenous population of hybrid cells (hybridoma) against determinant idiotypes (Id) which usually mimic human epitopes. Anti-Id vaccines may be effective in the treatment of B-cell lymphomas, resulting in tumor regression. Anti-idiotype vaccine therapy is less likely to induce autoimmunity if the target antigen is not normally expressed on normal tissues. Monoclonal antibodies have become powerful tools for tumor targeting, recognizing different protein markers on certain cancer cells and may be used alone or as delivery agents for drugs, toxins or radioactive material targeted to tumors.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5301</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/231</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5301</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>anti-Idiotype specified monoclonal antibody vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007264 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007264</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>anti-idiotypic mAb MK2-23+BCG</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:9816036</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4015</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/232</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4015</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>anti-idiotypic mAb MK2-23+BCG vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007265 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007265">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007265</metadata:prefixIRI>
        <obo:IAO_0000115>A murine anti-idiotypic monoclonal antibody (anti-Id MoAb) that is directed against an idiotype mimicking a disialoganglioside GD3. GD3 represents a major surface marker on most human melanoma cells. Due to poor immunogenicity of GD3, anti-Id MoAb BEC2 (Ab2) was raised against a mouse anti-GD3 MoAb, R24 (Ab1). This anti-Id MoAb was shown to be functionally mimicking GD3 in stimulating an immune response to produce Ab3 that may be used in combination with other adjuvants for treatment of melanomas.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5433</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/233</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5433</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>anti-idiotypic monoclonal antibody BEC2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007266 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007266">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007266</metadata:prefixIRI>
        <obo:IAO_0000115>An immunotherapeutic agent targeting the tumor-associated antigen (TAA), cancer/testis antigen NY-ESO-1, with potential antineoplastic activity.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5485</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/234</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5485</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>anti-NY-ESO-1 Immunotherapeutic GSK-2241658A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007267 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007267">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007267</metadata:prefixIRI>
        <obo:IAO_0000115>Human autologous CD62L-positive T-lymphocytes transduced with a retroviral vector encoding a T cell receptor (TCR) specific for the cancer-testis antigen NY-ESO-1, with potential antineoplastic activity. Following leukapheresis, isolation of lymphocytes, expansion ex vivo, transduction, and reintroduction into the patient, the anti-NY-ESO1 TCR-transduced autologous CD62L+-derived T-Lymphocytes bind to NY-ESO-1-overexpressing tumor cells. This may result in cytotoxic T-lymphocyte (CTL)-mediated elimination of NY-ESO-1-positive cancer cells. NY-ESO-1, a tumor associated antigen (TAA), is found in normal testis and on the surface of various tumor cell types. CD62L, also called L-selectin, is a lymphoid homing receptor and differentiation marker and is expressed on a subset of CD8-positive T-lymphocytes; it is involved in the migration of T-lymphocytes to lymph nodes and may improve the efficacy for ex vivo-expanded T-cells following adoptive cell therapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5081</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/235</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>30484</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5081</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG2</rdfs:comment>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>anti-NY-ESO1 TCR-transduced Autologous CD62L+-derived T-Lymphocytes vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007268 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007268">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007268</metadata:prefixIRI>
        <obo:IAO_0000115>Human autologous peripheral blood lymphocytes (PBLs) transduced with an anti-p53 T cell receptor gene with potential antineoplastic activity. PBLs are harvested from a patient and pulsed with a retroviral vector that encodes the T-cell receptor gene specific for a mutated form of p53. The transduced PBLs are then expanded in culture. When reintroduced to the patient, these modified PBLs express the anti-p53 T cell receptor which binds to mutant p53-overexpressing tumor cells; PBL-mediated tumor growth inhibition may follow. Many tumor cell types overexpress mutant p53 proteins, which are associated with the loss of apoptosis regulation and abnormal cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00393029</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5447</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/236</obo:IAO_0000233>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5447</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TP53 (P53)</rdfs:comment>
        <rdfs:label>anti-p53 T-Cell Receptor-Transduced peripheral blood lymphocytes vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007269 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007269">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
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            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007269</metadata:prefixIRI>
        <obo:IAO_0000115>An immunotherapeutic agent targeting the tumor-associated antigen (TAA), preferentially expressed antigen of melanoma (PRAME), with potential antineoplastic activity.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01853878</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5361</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/237</obo:IAO_0000233>
        <obo:OGG_0000000006>23532</obo:OGG_0000000006>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5361</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PRAME</rdfs:comment>
        <rdfs:label>anti-PRAME Immunotherapeutic GSK2302032A Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007270 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007270</metadata:prefixIRI>
        <obo:IAO_0000115>An individualized, therapeutic cancer vaccine (IVAC) composed of liposomes containing RNA encoding two or three tumor associated antigens (TAAs) that are specifically expressed in the patient&apos;s individual cancer selected from a warehouse (&quot;&quot;off the shelf&quot;&quot;) and p53 RNA, with potential immunostimulatory and antineoplastic activities. Upon administration, the antigen-targeted personalized breast cancer vaccines are translated by antigen presenting cells (APCs) and the expressed protein is presented via major histocompatibility complex (MHC) molecules on the surface of the APCs. This leads to an induction of both cytotoxic T-lymphocyte (CTL) and memory T-cell immune responses against the TAAs. The RNAs in the vaccine are specifically selected for an individual patient after RNA profiling of the patient&apos;s tumor.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5138</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/238</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
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        <obo:VO_0001818>5138</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>antigen-targeted Personalized Breast Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007271 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007271</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based vaccine composed of previously frozen autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01133704</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5420</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/239</obo:IAO_0000233>
        <obo:OGG_0000000006>2346</obo:OGG_0000000006>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:OGG_0000000006>55</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5420</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ACPP</rdfs:comment>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:comment>Gene name: Prostate</rdfs:comment>
        <rdfs:label>APC8015F vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007272">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007272</metadata:prefixIRI>
        <obo:IAO_0000115>A cell based cancer vaccine composed of mature polarized dendritic cells (DCs) and pulsed with apoptotic autologous tumor cells that has potential immunostimulating and antineoplatic activities. Dendritic cells (DCs) were treated with interleukin-1beta, tumor necrosis factor alpha, interferon-alpha (IFN-a), IFN-gamma and polyinosinic:polycytidylic acid (p-I:C) to produce mature alpha type-1 polarized DCs (alphaDC1) that are capable of producing high levels of interleukin-12p70 (IL-12p70). The alphaDC1 are subsequently pulsed with apoptotic autologous tumor cells. Upon administration, these DCs are able to induce a potent cytotoxic T lymphocyte (CTL) response against tumor associated antigens (TAAs), resulting in tumor cell lysis and inhibition of tumor cell growth. Apoptotic tumor cells contain an array of TAAs</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:21509164</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5222</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/240</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5222</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Apoptotic Autologous Tumor Cells-pulsed Alpha-type-1 Polarized Dendritic Cells Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007273">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007273</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that uses adenovirus MUC1 and Survivin transfected autologous dendritic cells combined with cytokine-induced killer cells in cancer patients with Extensive-Stage Small- Cell Lung Cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01174082</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6261</obo:IAO_0000119>
        <obo:OGG_0000000006>332</obo:OGG_0000000006>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6261</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:comment>Gene name: Survivin</rdfs:comment>
        <rdfs:label>adenovirus-transfected autologous dc vaccine plus cik cells</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007274 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007274">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007274</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine comprised of autologous epithelial ovarian cells infected with ALVAC-hB7.1</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5319</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.clincosm.com/trial/recurrent-ovarian-epithelial-cancer-houston-alvac-hb71-recombinant</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/242</obo:IAO_0000233>
        <obo:OGG_0000000006>155971</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5319</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: env</rdfs:comment>
        <rdfs:label>AUT-OV-ALVAC-hB7.1 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007275 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007275</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous tumor cell vaccine containing chronic lymphocytic leukemia (CLL) B cells transduced with an adenoviral vector carrying chimeric CD154 (ad-CD154) with potential antineoplastic activity. Administration of autologous ad-CD154 transduced CLL B cells may result in increases in the numbers of leukemia-specific CD4+ T cells and high serum-levels of IL-12 and IFN-gamma. Due to ligation of CD154 to CD40 on CLL cells, this agent may induce CLL cells to express the proapoptotic molecule BID and death receptors CD95 (Fas) and DR5, rendering CLL B cells first resistant and then sensitive to Fas-mediated apoptosis. In addition, autologous ad-CD154 transduced CLL B cells may induce MHC class I-dependent cytotoxic T lymphocyte (CTL) responses against autologous leukemia cells. CD154 is a type II membrane glycoprotein and ligand for CD40; both molecules are important in cognate co-stimulatory cell-cell interactions.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00779883</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5053</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/243</obo:IAO_0000233>
        <obo:OGG_0000000006>959</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5053</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40LG</rdfs:comment>
        <rdfs:label>Autologous Ad-CD154-Transduced CLL B Cells Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007276 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007276">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007276</metadata:prefixIRI>
        <obo:IAO_0000115>Human autologous peripheral blood lymphocytes (PBLs) transduced with a glycoprotein 100 (gp100) epitope-determined T cell receptor (TCR) gene, with potential antineoplastic activity. PBLs are isolated from a melanoma patient and pulsed with a viral vector encoding the TCR specific for amino acid residues 154-162 of gp100 (KTWGQYWQV). After expansion ex vivo, the transduced autologous PBLs, expressing this specific TCR, are reintroduced into the patient and bind to melanoma cells expressing the gp100 protein, which may result in specific cytotoxic T-lymphocyte (CTL) killing of gp100-expressing melanoma cells. gp100 is a melanocyte lineage-specific antigen overexpressed in melanomas.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00509496</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5507</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/244</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5507</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>autologous anti-gp100:154-162 T-cell receptor gene-engineered peripheral blood lymphocytes vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007277 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007277">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007277</metadata:prefixIRI>
        <obo:IAO_0000115>Human autologous peripheral blood lymphocytes (PBLs) transduced with a melanoma antigen MART-1 epitope-determined T cell receptor (TCR) gene, with potential antineoplastic activity. PBLs are isolated from a melanoma patient and pulsed with a viral vector that encodes the TCR specific for an epitope of MART-1 (F5 TCR). After expansion ex vivo, the transduced autologous PBLs, expressing this specific TCR, are reintroduced into the patient, and bind to melanoma cells expressing the MART-1 antigen, which may result in specific cytotoxic T-lymphocyte (CTL) killing of MART-1-expressing melanoma cells. MART-1 (melanoma antigen recognized by T cells 1), also known as Melan-A, is a melanocyte lineage-specific transmembrane protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00509288</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5293</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/245</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5293</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:label>autologous anti-mart-1 f5 T-cell receptor gene-engineered peripheral blood lymphocytes vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007278">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007278</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous dendritic cells (DCs) loaded with CD133-positive autologous brain tumor stem cells (BTSCs) -derived mRNA with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, autologous CD133-positive BTSC mRNA-pulsed autologous dendritic cell vaccine may elicit a cytotoxic T-lymphocyte (CTL) response against the CD133-positive BTSCs from which the autologous tumor mRNA is derived. CD133, a tumor-associated antigen (TAA) and neural stem cell marker, has been found on a specific subset of glioblastoma multiforme (GBM) stem cells; its presence has been correlated with resistance to conventional chemotherapy and radiotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5463</obo:IAO_0000119>
        <obo:IAO_0000119>https://mhlw-grants.niph.go.jp/system/files/2013/134041/201328051A/201328051A0017.pdf</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/246</obo:IAO_0000233>
        <obo:OGG_0000000006>8842</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5463</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PROM1</rdfs:comment>
        <rdfs:label>Autologous CD133-Positive BTSC mRNA-Pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007279 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007279">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005487"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007279</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous, B-chronic lymphocytic leukemia (B-CLL) cells harvested from a patient and transduced with an adenoviral vector encoding the gene for the human CD40 ligand (CD40L; TRAP; CD154), with potential immunostimulating and antineoplastic activities. Upon reintroduction into the patient, the autologous CD40L-expressing B-CLL vaccine expresses the co-stimulatory molecule CD40L, which binds to its cognate receptor, CD40, on antigen presenting cells (APC). This induces apoptosis, stimulates maturation and proliferation of APCs, and facilitates a cytotoxic T-lymphocyte (CTL) response against tumor cells. CD40L is a type II membrane protein that binds to CD40, which is a cell surface receptor that belongs to the tumor necrosis factor (TNF) receptor superfamily.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5174</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/247</obo:IAO_0000233>
        <obo:OGG_0000000006>959</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5174</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40LG</rdfs:comment>
        <rdfs:label>Autologous CD40L-expressing B-CLL Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007280">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007280</metadata:prefixIRI>
        <obo:IAO_0000115>A dendritic cell (DC)-based cancer vaccine composed of autologous DCs pulsed with tumor cell lysates from a colorectal cancer patient containing tumor-associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous colorectal tumor antigen-pulsed DC vaccine exposes the immune system to colorectal tumor cell antigens, which may result in cytotoxic T-lymphocyte (CTL)-mediated immune responses against the colorectal cancer cells. This leads to cancer cell lysis. The tumor cell lysate contains a range of antigens that are essential for the neoplastic growth and survival of the cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5150</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/248</obo:IAO_0000233>
        <obo:OGG_0000000006>174</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5150</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: AFP</rdfs:comment>
        <rdfs:label>Autologous Colorectal Tumor Antigen-pulsed Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007281">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005492"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007281</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous tumor cell vaccine containing CD34+ hematopoietic progenitor cell (HPC)-derived Langerhans-type dendritic cells (LCs) electroporated with mRNA encoding the full-length cancer-testis antigens, CT7 and melanoma-associated antigen 3 (MAGE-A3), and the self-differentiation tumor antigen, Wilms tumor 1 (WT1) with potential immunomodulating and antineoplastic activity. The autologous CT7/MAGE-A3/WT1 mRNA-electroporated Langerhans-type dendritic cells are prepared by drawing a blood sample containing the CD34+ HPCs from a cancer patient. The CD34+ HPCs are treated with a combination of cytokines which specifically support LC development, and the LC population is enriched and expanded ex vivo. The cultured LCs are allowed to mature for one day and then electroporated separately with CT7, MAGE-A3 or WT1 mRNA before final maturation. Upon intradermal administration into the patient, the mature LCs may activate cell-mediated immunity and induce both cytotoxic CD8+ T cells and CD4+ helper T cells against cancer cells expressing CT7, MAGE-A3 and WT1 tumor antigens. This may result in the immune-mediated inhibition of tumor cell proliferation, leading to tumor cell death. CT7 and MAGE-A3 are tumor-specific proteins overexpressed in a number of cancers but not in healthy tissues other than testis and placenta. WT1 is a transcription factor important in development and cancer pathogenesis, which is overexpressed in a variety of cancers, including multiple myeloma, leukemia, ovarian cancer, malignant mesothelioma, neural tumors and renal carcinoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01995708</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5128</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/249</obo:IAO_0000233>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5128</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>Autologous CT7/MAGE-A3/WT1 mRNA-Electroporated Langerhans-Type Dendritic Cells Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007282 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007282</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>autologous DCV</obo:IAO_0000118>
        <obo:IAO_0000118>autologous dendritic cell vaccine (DCV)</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:22774527</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:31771601</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:34862245</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3967</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/250</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>3967</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous dendritic cell vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007283 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007283</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous, immature dendritic cells (DCs), with potential immunostimulating and antineoplastic activities. Upon leukapheresis, immature DCs are isolated and re-administered intra-tumorally. The immature DCs internalize and process the tumor-associated antigens (TAAs), migrate to the lymphatic system, and then expose the immune system to the TAAs. This induces a specific cytotoxic T-lymphocyte (CTL) response against the cancer cells leading to tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02649829</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5085</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/251</obo:IAO_0000233>
        <obo:OGG_0000000006>958</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5085</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40</rdfs:comment>
        <rdfs:label>Autologous Dendritic Cell Vaccine ACT2001</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007284 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007284</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of autologous dendritic cells (DCs) that have been transduced ex vivo with an adenoviral vector containing the CCL21 gene with potential immunostimulatory and antineoplastic activities. Upon intratumoral administration, autologous dendritic cell-adenovirus CCL21 vaccine expresses the chemokine CCL21, which may induce an antitumoral cytotoxic immune response in the tumor microenvironment. CCL21 [chemokine (C-C motif) ligand 21] has been shown to attract antigen presenting cells (APCs), like leukocytes and DCs, and natural killer (NK) cells and their T-cell effectors to induce a cytotoxic immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT03546361</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5030</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/252</obo:IAO_0000233>
        <obo:OGG_0000000006>6366</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5030</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CCL21</rdfs:comment>
        <rdfs:label>Autologous Dendritic Cell-Adenovirus CCL21 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007285 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007285</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous vaccine composed of dendritic cells (DC) that have been transduced with a p53 tumor suppressor gene-modified virus. When the autologous dendritic cell-adenovirus p53 vaccine is administered, the host cytotoxic T lymphocytes (CTL) are directed against p53-positive tumor cells, which may result in tumor cell death and decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:20420527</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:29515795</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5088</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/253</obo:IAO_0000233>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5088</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TP53 (P53)</rdfs:comment>
        <rdfs:label>autologous dendritic cell-Adenovirus P53 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007286 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007286</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from heat-treated allogeneic melanoma tumor cells. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T-cell and antibody responses to melanoma cells bearing shared melanoma antigens such as MelanA/MART-1, gp100, MAGE3, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5495</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/254</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5495</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>autologous dendritic cell-allogeneic melanoma tumor cell lysate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007287 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007287</metadata:prefixIRI>
        <obo:IAO_0000115>cancer vaccine consisting of autologous dendritic cells transfected with autologous tumor mRNA and the human CD40 ligand (CD40L) gene with immunostimulatory and antitumor activities. Vaccination with autologous dendritic cell-autologous tumor mRNA-human CD40L vaccine may elicit a cytotoxic T cell response against tumor cells from which the autologous tumor mRNA was derived. When expressed by dendritic cells, tumor antigens and the co-stimulatory molecule CD40L, which binds to CD40 receptors on antigen presenting cells (APC), facilitate both humoral and cellular immune responses against tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:20884622</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5066</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/255</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
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        <obo:VO_0001818>5066</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>Autologous Dendritic Cell-Autologous Tumor mRNA-Human CD40L Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007288 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007288">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007288</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic interleukin-12 (IL-12)-expressing dendritic cell (DC)-based vaccine composed of autologous monocyte-derived DCs loaded with autologous tumor cell lysate and exposed to the microbial cell wall component lipopolysaccharide (LPS), with potential immunomodulating and antineoplastic activities. The monocyte-derived immature DCs are loaded with autologous tumor cell lysates and are subsequently exposed to LPS and interferon-gamma (IFN-gamma). Upon administration of autologous DC-based immunotherapeutic AV0113, the mature DCs migrate into the lymph nodes, express the immune stimulatory cytokine interleukin-12 (IL-12) and activate the immune system by promoting the activation of natural killer (NK) cells and induce a cytotoxic T-lymphocyte (CTL)-mediated immune response against tumor cells, which may result in immune-mediated tumor cell death and inhibition of tumor cell proliferation. Exposure to LPS and IFN-gamma allows the maturation of DCs and optimizes the presentation of tumor-associated antigens (TAAs) by DCs to T-lymphocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5284</obo:IAO_0000119>
        <obo:IAO_0000119>https://ascopubs.org/doi/10.1200/jco.2014.32.15_suppl.2052</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/256</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
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        <obo:VO_0001818>5284</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Autologous Dendritic Cell-based Immunotherapeutic AV0113 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007289 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007289">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007289</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic cancer vaccine consisting of autologous dendritic cells (DCs) fused with autologous tumor cells with potential immunostimulatory and antineoplastic activities. Autologous dendritic cell-tumor fusion vaccine is generated in vitro by mixing DCs and irradiated tumor cells harvested from individual patients and treating them with polyethylene glycol (PEG) to produce DC-tumor cell fusion hybrid cells. Upon administration, autologous dendritic cell-tumor fusion vaccine may elicit antitumor humoral and cellular immune responses.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:23685836</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5056</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/257</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:OGG_0000000006>6382</obo:OGG_0000000006>
        <obo:OGG_0000000006>952</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5056</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD38</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:comment>Gene name: SDC1</rdfs:comment>
        <rdfs:label>Autologous Dendritic Cell-Tumor Fusion Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007290 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007290">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007290</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of autologous cancer cells modified with the hapten, Dinitrophenyl. The treatment program consists of multiple intradermal injections of irradiated DNP-modified autologous tumor cells mixed with bacillus Calmette-Guerin.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:/9400626</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5537</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/258</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5537</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous dinitrophenyl vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007291 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007291">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007291</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous ovarian cancer cell peptide antigens conjugated to the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of autologous dinitrophenyl-modified ovarian cancer vaccine may induce a cytotoxic T-lymphocyte (CTL) response against ovarian cancer cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5459</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/259</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5459</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Autologous Dinitrophenyl-Modified Ovarian Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007292 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007292</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based vaccine composed of autologous tumor cells with Epstein-Barr virus-transformed B-lymphoblastoid cells. Upon administration, this vaccine may stimulate a cytotoxic T cell response against tumor cells, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5118</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/260</obo:IAO_0000233>
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        <obo:VO_0001818>5118</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Autologous EBV-Transformed B Lymphoblastoid-Tumor Fusion Cell Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007293 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007293</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based vaccine composed of autologous tumor cells fused with Epstein-Barr virus-transformed B-lymphoblastoid cells. Upon administration, this vaccine may stimulate a cytotoxic T cell response against tumor cells, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5225</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/261</obo:IAO_0000233>
        <obo:OGG_0000000006>1880</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5225</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GPR183</rdfs:comment>
        <rdfs:label>Autologous Epstein-Barr Virus-Transformed B-Lymphoblastoid Cell Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007294 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007294</metadata:prefixIRI>
        <obo:IAO_0000115>Multipotent self-renewing adherent non-hematopoietic stromal cells harvested from a patient&apos;s bone marrow and grown in vitro. When injected back into the patient, autologous expanded mesenchymal stem cells OTI-010 may differentiate into various mesenchyme-derived cell types and, in some instances, may augment bone marrow engraftment after whole-body irradiation.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5491</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/262</obo:IAO_0000233>
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        <obo:VO_0001818>5491</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Autologous Expanded Mesenchymal Stem Cells OTI-010 Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007295 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007295</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous tumor cell vaccine containing irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Autologous breast cancer cells are transduced ex vivo with an adenovirus vector encoding the GM-CSF gene and irradiated and then reintroduced into the patient. Upon repeated subcutaneous administration of the vaccine, autologous GM-CSF-secreting breast cancer cells secrete GM-CSF, which may stimulate a tumor-specific cytotoxic T-lymphocyte (CTL) response.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5250</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/263</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5250</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>Autologous GM-CSF-Secreting Breast Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007296 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007296</metadata:prefixIRI>
        <obo:IAO_0000115>A lethally irradiated, autologous colorectal cancer vaccine consisting of patient-specific colorectal cancer cells genetically modified to secrete the cytokine granulocyte-macrophage colony stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Upon vaccination, the autologous GM-CSF-secreting lethally irradiated colorectal cancer cell vaccine releases GM-CSF. In turn, GM-CSF may increase the body&apos;s immune response against tumor cells by promoting the maturation and activation of dendritic cells (DCs), and enhancing tumor-specific antigen presentation to both B- and T-cells, which leads to better recognition of tumors by the immune system. In addition, GM-CSF promotes antibody-dependent cellular cytotoxicity (ADCC), and increases interleukin-2-mediated lymphokine-activated killer cell function.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5188</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/264</obo:IAO_0000233>
        <obo:OGG_0000000006>10232</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5188</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MSLN</rdfs:comment>
        <rdfs:label>Autologous GM-CSF-secreting Lethally Irradiated Colorectal Cancer Cell Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007297 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007297</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous cancer vaccine composed of lethally irradiated leukemia cells that are genetically modified to secrete the immunostimulatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Upon intradermal injection, the autologous GM-CSF-secreting lethally irradiated leukemia cell vaccine secretes GM-CSF. In turn, GM-CSF may stimulate the immune system to attack tumor cells by enhancing the activation of dendritic cells (DCs) and promoting antigen presentation to both B- and T-lymphocytes. In addition, GM-CSF promotes antibody-dependent cellular cytotoxicity (ADCC), and increases interleukin-2-mediated lymphokine-activated killer cell function.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5240</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/265</obo:IAO_0000233>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
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        <obo:VO_0001818>5240</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:comment>Gene name: WT1</rdfs:comment>
        <rdfs:label>Autologous GM-CSF-Secreting Lethally Irradiated Leukemia Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007298 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007298</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5266</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/266</obo:IAO_0000233>
        <obo:OGG_0000000006>3308</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5266</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HSPA4</rdfs:comment>
        <rdfs:label>Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007299 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007299</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of lethally irradiated human fetal lung fibroblasts (Medical Research Council 5 or MRC-5) transfected with autologous tumor DNA derived from a head and neck squamous cell carcinoma (HNSCC), with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, the autologous HNSCC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine expresses HNSCC tumor-associated antigens (TAAs), which may activate the immune system to induce a cytotoxic T-lymphocyte (CTL) response against HNSCC cells. The MRC-5 cell line, established in 1966, is a human diploid lung fibroblast cell line derived from the human lung tissue of a 14-week-old male fetus.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02211027</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5043</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/267</obo:IAO_0000233>
        <obo:OGG_0000000006>6375</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5520"/>
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        <obo:VO_0001818>5043</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: XLC1</rdfs:comment>
        <rdfs:label>autologous HNSCC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007300 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007300</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous, B-chronic lymphocytic leukemia (B-CLL) cells harvested from a patient and transduced ex vivo with an adenoviral vector encoding the gene for the human cytokine interleukin-2 (IL-2), with potential immunostimulating and antineoplastic activities. Upon reintroduction into the patient, the autologous IL-2-expressing B-CLL vaccine expresses IL-2, stimulates natural killer (NK) cells, and may enhance the cytotoxic T-lymphocyte (CTL) immune response against the patient&apos;s B-CLL cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00458679</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5228</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/268</obo:IAO_0000233>
        <obo:OGG_0000000006>12519</obo:OGG_0000000006>
        <obo:OGG_0000000006>3383</obo:OGG_0000000006>
        <obo:OGG_0000000006>942</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
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        <obo:VO_0001818>5228</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD86</rdfs:comment>
        <rdfs:comment>Gene name: Cd80</rdfs:comment>
        <rdfs:comment>Gene name: ICAM1</rdfs:comment>
        <rdfs:label>Autologous IL-2-expressing B-CLL Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007301 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007301">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007301</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of tumor-specific idiotype determinants derived from an individual&apos;s tumor cells which are conjugated to keyhole limpet hemocyanin, an immunostimulant carrier protein. When injected into the individual from whom the tumor cells were isolated, this vaccine may stimulate an antitumoral cytotoxic T-lymphocytic immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00104819</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5057</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/269</obo:IAO_0000233>
        <obo:OGG_0000000006>3123</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5057</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HLA-DRB1</rdfs:comment>
        <rdfs:label>Autologous Immunoglobulin Idiotype-KLH Conjugate Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007302 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007302</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous lymphoma cells with potential immunostimulatory and antineoplastic activities. Upon intranodal administration, autologous lymphoma cell lysate-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against lymphoma cells, which may result in lymphoma cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5248</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/270</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5248</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Autologous Lymphoma Cell Lysate-Pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007303 -->

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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007303</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine consisting of hybrid cells created by electrofusing allogeneic dendritic cells (DCs) and autologous lymphoma cells with potential immunostimulating and antitumor activities. Upon administration, autologous lymphoma cell/allogeneic dendritic cell electrofusion hybrid vaccine may stimulate the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against specific autologous lymphoma-associated antigens, resulting in lymphoma cell apoptosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5503</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/272</obo:IAO_0000233>
        <obo:OGG_0000000006>1638</obo:OGG_0000000006>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5503</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: DCT</rdfs:comment>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: Tyrosinase</rdfs:comment>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>Autologous Lymphoma Cell/Allogeneic Dendritic Cell Electrofusion Hybrid Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007304 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007304</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine consisting of hybrid cells created by electrofusing autologous dendritic cells (DCs) and autologous lymphoma cells with potential immunostimulating and antitumor activities. Upon administration, autologous lymphoma cell/autologous dendritic cell electrofusion hybrid vaccine may stimulate the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against specific autologous lymphoma-associated antigens, resulting in lymphoma cell apoptosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5431</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/273</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5431</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Autologous Lymphoma Cell/Autologous Dendritic Cell Electrofusion Hybrid Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007305 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007305</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous melanoma cells containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against melanoma cells, which may result in melanoma cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5148</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/274</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
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        <obo:VO_0001818>5148</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA-Dupuli</rdfs:comment>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>autologous melanoma lysate-pulsed autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007306 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007306</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous melanoma cells containing tumor associated antigens (TAAs) and conjugated to the immunostimulant Keyhole limpet hemocyanin (KLH), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate/KLH-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against melanoma cells, which may result in melanoma cell lysis. KLH is an immunogenic carrier and serves as an immunostimulant to improve antigenic immune recognition and T-cell responses and can be used to evaluate vaccine efficacy.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5213</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/275</obo:IAO_0000233>
        <obo:OGG_0000000006>3123</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5213</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HLA-DRB1</rdfs:comment>
        <rdfs:label>autologous melanoma Lysate/KLH-pulsed autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007307 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007307">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007307</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with both a lysate from autologous melanoma cells containing tumor associated antigens (TAAs) and a synthetic peptide derived from the tumor associated antigen human cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate/NY-ESO-1-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody-mediated immune responses against melanoma cells, which may result in melanoma cell lysis. NY-ESO-1 is expressed in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5158</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/276</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5158</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>autologous melanoma Lysate/NY-ESO-1-pulsed autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007308 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007308</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of irradiated human fetal lung fibroblasts (Medical Research Council 5 or MRC-5) transfected with autologous non-small cell lung cancer (NSCLC)-derived DNA with potential immunostimulatory and antineoplastic activities. Upon administration, autologous NSCLC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine expresses NSCLC tumor-associated antigens (TAAs) in addition to MHC class I-determinants and the co-stimulatory molecule B7.1, which may induce a cytotoxic T-lymphocyte (CTL) response against NSCLC cells. The MRC-5 cell line is a human diploid lung fibroblast cell line extablished in 1966.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5377</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/277</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5377</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Autologous NSCLC DNA-Transfected Semi-Allogeneic Fibroblasts MRC-5 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007309 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007309">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007309</metadata:prefixIRI>
        <obo:IAO_0000115>A personalized cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with immunogenic peptides derived from autologous non-small cell lung cancer (NSCLC) cells, with potential immunostimulating and antineoplastic activities. During leukapheresis, mature DCs are loaded with autologous NSCLC-derived peptides. Upon re-administration of the NSCLC peptide-specific DC vaccine, the immune system is exposed to NSCLC-associated antigens. This results in the induction of a specific cytotoxic T-lymphocyte (CTL) response against NSCLC cells and tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5311</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/278</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5311</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Autologous NSCLC Peptide-specific Dendritic Cell Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007310 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007310</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous, mature monocyte-derived dendritic cells (DCs) transfected with oncofetal antigen immature laminin receptor protein (OFA-iLRP) RNA, with potential antineoplastic activity. Upon administration, DCs in the OFA-iLRP RNA-transfected autologous dendritic cell vaccine express, process, and present OFA-iLRP to the host immune system, which may mount a potent cytotoxic T-cell (CTL) response against OFA-iLRP-expressing tumor cells. As a highly conserved protein, OFA-iLRP is preferentially expressed in fetal tissues and in many types of cancer, including hematopoietic malignancies, but is not detectable in normal differentiated adult cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00715832</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5368</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/279</obo:IAO_0000233>
        <obo:OGG_0000000006>16785</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5368</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Rspa</rdfs:comment>
        <rdfs:label>Autologous OFA-iLRP RNA-Transfected Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007311 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007311">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007311</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous, irradiated dendritic cells (DCs) pulsed with ovarian tumor cell lysate containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous ovarian tumor cell lysate-pulsed dendritic cell vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against ovarian tumor cells expressing the patients ovarian tumor cell-specific TAAs, which may result in ovarian tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5427</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/280</obo:IAO_0000233>
        <obo:OGG_0000000006>5427</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5427</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>Autologous Ovarian Tumor Cell Lysate-Pulsed Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007312 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007312">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007312</metadata:prefixIRI>
        <obo:IAO_0000115>A specific population of autologous, pluripotent bone marrow derived cells that express high levels of the cytosolic enzyme aldehyde dehydrogenase (ALDH) with potential protective and neuro-cognition improving activity. Expression of high levels of ALDH is an indicator of the biological activity in heterogenous early stage stem cells. Upon intravenous administration, these ALDH bright cells may protect normal cells and may repair damaged cells. These cells may also protect brain cells from damage and may improve neurocognition.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5220</obo:IAO_0000119>
        <obo:IAO_0000119>https://discovery.lifemapsc.com/regenerative-medicine/cell-therapy-applications/brain-ald451-bone-marrow-derived-cells-for-malignant-glioma</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/281</obo:IAO_0000233>
        <obo:OGG_0000000006>216</obo:OGG_0000000006>
        <obo:OGG_0000000006>217</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5220</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ALDH1A1</rdfs:comment>
        <rdfs:comment>Gene name: ALDH2</rdfs:comment>
        <rdfs:label>Autologous Pluripotent ALDHbr Stem Cells ALD-451 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007313 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007313">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007313</metadata:prefixIRI>
        <obo:IAO_0000115>A genetically-modified autologous dendritic cell-based vaccine expressing a drug-inducible costimulatory CD40 receptor (iCD40) with potential immunomodulating and antineoplastic activities. Autologous dendritic cells (DCs) are genetically modified to express the iCD40 receptor and are pulsed with the tumor antigen prostate-specific membrane antigen (PSMA). Upon intradermal administration, these DCs accumulate in local draining lymph nodes. Twenty-four hours after vaccination, the dimerizer agent AP1903 is administered; AP1903 binds to and activates iCD40 receptors presented on DC surfaces, thus activating the DCs and stimulating a cytotoxic T-lymphocyte (CTL) response against host tumor cells that express PSMA. This delayed activation strategy optimizes DC accumulation in local draining lymph nodes prior to DC activation. iCD40 contains a membrane-localized cytoplasmic CD40 domain fused to a drug-binding domain.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5282</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/282</obo:IAO_0000233>
        <obo:OGG_0000000006>2346</obo:OGG_0000000006>
        <obo:OGG_0000000006>928</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5282</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40</rdfs:comment>
        <rdfs:comment>Gene name: Prostate</rdfs:comment>
        <rdfs:label>Autologous Prostate Cancer Antigen-expressing Dendritic Cell Vaccine BPX-101</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007314 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007314">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007314</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with renal cell carcinoma (RCC) tumor cell lysate containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous renal cell carcinoma tumor lysate-dendritic cell vaccine may stimulate anti-tumoral cytotoxic T-lymphocyte (CTL) and antibody responses against RCC tumor cells expressing RCC TAAs, resulting in RCC tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5018</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/283</obo:IAO_0000233>
        <obo:OGG_0000000006>2315863</obo:OGG_0000000006>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5018</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Survivin</rdfs:comment>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>Autologous Renal Cell Carcinoma Tumor Lysate-Pulsed Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007315 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007315">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005495"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007315</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from sarcoma cells with potential immunostimulatory and antineoplastic activities. Upon administration, the autologous sarcoma lysate-pulsed dendritic cell vaccine exposes the immune system to an undefined amount of sarcoma-type tumor associated antigens (TAA), which may result in the induction of both specific anti-tumoral cytotoxic T lymphocytes (CTL) and antibody-dependent responses against the sarcoma TAA-expressing cells, resulting in sarcoma cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5189</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/284</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5189</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Autologous Sarcoma Lysate-pulsed Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007316 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007316">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007316</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with autologous T cell receptor gamma-chain alternate reading frame protein (TARP) peptide with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, autologous TARP peptide-pulsed dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against TARP-expressing cancer cells, resulting in tumor cell lysis. The highly immunogenic nuclear protein TARP is commonly expressed in breast and prostate cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02362451</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5024</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/285</obo:IAO_0000233>
        <obo:OGG_0000000006>6862</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5024</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TBXT</rdfs:comment>
        <rdfs:label>Autologous TARP Peptide-Pulsed Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007317 -->

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            </owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007317</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of autologous, mature dendritic cells (DCs) are electroporated with in vitro transcribed (IVT) RNAs encoding for a synthetic form of T-cell protein CD40 ligand (CD40L) and IVT RNA encoding for autologous tumor-associated antigens (TAAs) derived from patient-specific bladder cell carcinoma (BCC) cells, with potential immunostimulatory and antineoplastic activities. The RNA is translated and processed, and BCC-specific antigenic peptides are subsequently presented via major histocompatibility complex (MHC) Class I molecules on the DCs surface. The MHC-presented peptides interact with and activate CD8-positive T-cells, which elicits a highly specific cytotoxic T-cell (CTL) response against tumor cells expressing the patient-specific BCC TAAs. The signal cascade initiated by expression of the co-stimulatory molecule CD40L results in the secretion of the inflammatory cytokine IL-12, which further stimulates CTLs. The vaccine can be used in combination with gemcitabine hydrochloride and cisplatin which stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading, while the vaccine helps the body build an effective immune response to kill tumor cells. In combination, they may make the tumor smaller and reduce the amount of tissue that needs to be removed by surgery in patients with bladder cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C129522</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02944357</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6363</obo:IAO_0000119>
        <obo:OGG_0000000006>959</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6363</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40LG</rdfs:comment>
        <rdfs:label>ags-003-bld vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007318 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007318">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005487"/>
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            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007318</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous chronic lymphocytic leukemia cancer vaccine consisting of patient-specific membrane proteins directly extracted from patient autologous tumor cells and incorporated into liposomes along with Interleukin 2 (IL-2) to produce membrane-patched proteoliposomes, with potential immunostimulating and antineoplastic activities. After subcutaneous injection of the autologous tumor cell proteoliposomes chronic lymphocytic leukemia vaccine, liposomes deliver the encapsulated tumor antigens into the cytosol of antigen presenting cells (APCs). Subsequently, the APCs process the antigens and present antigen-derived peptides to the immune system. This may enhance recognition of tumors by the immune system, and activate both cytotoxic CD8+ T cells and CD4+ helper T cells against tumor cells. IL-2 is incorporated into the vaccine to leverage its ability to expand activated T cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5108</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/287</obo:IAO_0000233>
        <obo:OGG_0000000006>3558</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5108</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IL2</rdfs:comment>
        <rdfs:label>Autologous Tumor Cell Proteoliposome Chronic Lymphocytic Leukemia Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007319</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic agent produced by isolating tumor cells from an individual and processing these tumor cells into a vaccine formulation in vitro; the vaccine is then administered to the individual from whom the tumor cells were isolated. Typically combined with an adjuvant immunostimulant, an autologous cell vaccine may elicit a cytotoxic T-lymphocytic immune response to cell surface-expressed tumor-associated antigens (TAAs), resulting in tumor cell death.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22854664</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:32558897</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5396</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/288</obo:IAO_0000233>
        <obo:OGG_0000000006>942</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0050746"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5396</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD86</rdfs:comment>
        <rdfs:label>autologous tumor cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007320">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007320</metadata:prefixIRI>
        <obo:IAO_0000115>A dendritic cell (DC)-based cancer vaccine composed of autologous DCs pulsed with specific tumor-associated peptide antigens (TAPA), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous TAPA-pulsed DC vaccine exposes the immune system to the specific TAPAs, which may result in cytotoxic T-lymphocyte (CTL)-mediated immune responses against the TAPA-expressing cancer cells. This leads to cancer cell lysis. This vaccine is specific towards peptides derived from the following proteins: sperm autoantigenic protein 17 (SP17), ropporin, A-kinase anchor protein 4 (AKAP4), pituitary tumor-transforming 1 (PTTG1) and SPANX family member B (SPANX-B).</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:18528294</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:23482679</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5035</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/289</obo:IAO_0000233>
        <obo:OGG_0000000006>53340</obo:OGG_0000000006>
        <obo:OGG_0000000006>54763</obo:OGG_0000000006>
        <obo:OGG_0000000006>728695</obo:OGG_0000000006>
        <obo:OGG_0000000006>8852</obo:OGG_0000000006>
        <obo:OGG_0000000006>9232</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5035</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: AKAP4</rdfs:comment>
        <rdfs:comment>Gene name: PTTG1</rdfs:comment>
        <rdfs:comment>Gene name: ROPN1</rdfs:comment>
        <rdfs:comment>Gene name: SPA17</rdfs:comment>
        <rdfs:comment>Gene name: SPANXB1</rdfs:comment>
        <rdfs:label>autologous tumor-associated peptide antigen-pulsed dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007321 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007321">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007321</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous therapeutic vaccine for the treatment of acute myelogenous leukemia. This vaccine is prepared from blood samples of patients following their first relapse. Tumor cells extracted from blood sample are modified with hapten, a process that makes the cells appear foreign to the patient&apos;s body and results in stimulating immune response against the cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5404</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/290</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5404</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:label>Autologous-Cell Leukemia Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007322 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007322">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007322</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous-cell vaccine for melanoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5110</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/291</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5110</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous-cell melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007323 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007323">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003140"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_3908"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007323</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that restored priming of Anaplastic lymphoma kinase (ALK)-specific CD8+ T cells, eradicated lung tumors in combination with ALK tyrosine kinase inhibitors (TKIs) and prevented metastatic dissemination of tumors to the brain. Human ALK peptides are displayed by HLA-A*02:01 and HLA-B*07:02 molecules. The peptides are immunogenic and recognized by CD8+ T cells from individuals with non-small cell lung cancer (NSCLC).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:37430060</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6382</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3908"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6382</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>alk peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007324 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007324">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007658"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007324</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made of allogeneic pancreatic tumor cells are transfected with a GM-CSF gene to treat ocally advanced, unresectable or metastatic pancreatic adenocarcinoma. It may be in combination with Ipilimumab (an antibody that blocks negative signals to T cells).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00836407</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6336</obo:IAO_0000119>
        <obo:OGG_0000000006>12981</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6336</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:label>allogeneic GM-CSF-secreting lethally irradiated pancreatic tumor cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007325 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007325">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007658"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007325</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that consists of an allogeneic cell line that has a high expression level of melanoma molecules (HLA A2/4-1BB Ligand), and has been genetically modified to induce a strong immune response. Stimulation of the immune response against the tumor can help destroy residual tumor in melanoma patients with very high risk for disease recurrence and in patients with relatively low tumor burden who already got first line treatment for their disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01861938</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6313</obo:IAO_0000119>
        <obo:OGG_0000000006>3105</obo:OGG_0000000006>
        <obo:OGG_0000000006>8744</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6313</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: 4-1BBL</rdfs:comment>
        <rdfs:comment>Gene name: HLA-A</rdfs:comment>
        <rdfs:label>allogeneic HLA-A2/4-1BB ligand-expressing melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007326 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007326">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007326</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that uses anti-HER2/HER3 dendritic cells in combination with Pembrolizumab in patients with Asymptomatic Brain Metastasis From Triple Negative Breast Cancer (TNBC) or HER2+ Breast Cancer (HER2+BC). The dendritic cells boost the immune system, and the Pembrolizumab enhances cancer immune responses, in combination they may shrink the cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04348747</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6263</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:OGG_0000000006>2065</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6263</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HER2</rdfs:comment>
        <rdfs:comment>Gene name:HER3</rdfs:comment>
        <rdfs:label>anti-HER2/HER3 dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007327 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007327">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005485"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007327</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:21036724</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5230</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/296</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5230</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG, Cell Wall Skeleton Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007328 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007328">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007328</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of replication-defective recombinant adenovirus that encodes for Bcl-Xs with potential antineoplastic activity. Vaccination with Bcl-Xs adenovirus vaccine induces apoptosis in Bcl-2 and Bcl-XL positive cancer cells, resulting in decreased tumor growth while leaving normal cells unaffected. Bcl-Xs block the function of the protooncogenes Bcl-2 and Bcl-XL which are overexpressed in a variety of solid tumors and promote cancer cell survival by inhibiting apoptosis. (NCI04)A vaccine consisting of replication-defective recombinant adenovirus that encodes for Bcl-Xs with potential antineoplastic activity. Vaccination with Bcl-Xs adenovirus vaccine induces apoptosis in Bcl-2 and Bcl-XL positive cancer cells, resulting in decreased tumor growth while leaving normal cells unaffected. Bcl-Xs block the function of the protooncogenes Bcl-2 and Bcl-XL which are overexpressed in a variety of solid tumors and promote cancer cell survival by inhibiting apoptosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:7479929</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5399</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/297</obo:IAO_0000233>
        <obo:OGG_0000000006>598</obo:OGG_0000000006>
        <obo:OGG_0000000006>7306</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5399</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: BCL2L1</rdfs:comment>
        <rdfs:comment>Gene name: TYRP1</rdfs:comment>
        <rdfs:label>Bcl-Xs adenovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007329 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007329</metadata:prefixIRI>
        <obo:IAO_0000115>A transforming growth factor beta2 (TGF-beta2) antisense gene-modified allogeneic tumor cell vaccine with potential immunostimulatory and antineoplastic activities. Belagenpumatucel-L is prepared by transfecting allogeneic non-small cell lung cancer (NSCLC) cells with a plasmid containing a TGF-beta2 antisense transgene, expanding the cells, and then irradiating and freezing them. Upon administration, this agent may elicit a cytotoxic T lymphocyte (CTL) response against host NSCLC cells, resulting in decreased tumor cell proliferation; vaccine immunogenicity may be potentiated by suppression of tumor TGF-beta2 production by antisense RNA expressed by the vaccine plasmid TGF-beta2 antisense transgene. Elevated levels of TGF-beta2 are frequently linked to immunosuppression in cancer patients and may be inversely correlated with prognosis in patients with NSCLC.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:26211534</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5374</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/298</obo:IAO_0000233>
        <obo:OGG_0000000006>7042</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5374</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TGFB2</rdfs:comment>
        <rdfs:label>Belagenpumatucel-L Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007330 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007330">
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007330</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic vaccine combining the peptide antigens of two proteins, ras oncoprotein and tumor suppressor p53</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15983396</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4992</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/299</obo:IAO_0000233>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4992</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TP53 (P53)</rdfs:comment>
        <rdfs:label>Berzofsky Ras/P53 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007331 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007331">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007331</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of a replication-deficient, attenuated derivative of the vaccinia virus strain Ankara expressing both a CD8+ T-cell epitope from the brachyury protein and a triad of T-cell co-stimulatory molecules (MVA Brachyury-TRICOM), with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration of the brachyury-expressing modified vaccinia Ankara (MVA)-TRICOM vaccine, the expressed brachyury protein induces specific CD8+ and CD4+ T-cell responses against brachyury-expressing tumor cells. This causes both tumor cell lysis and a decrease in the growth of brachyury-expressing tumor cells. Brachyury, a member of the T-box family of transcription factors that is overexpressed in numerous cancer cell types, is correlated with increased epithelial-mesenchymal transition (EMT), cancer resistance and cancer progression. TRICOM, a triad of three human T-cell co-stimulatory molecules, B7.1, ICAM-1 and LFA-3, enhances antigen-specific T-cell activation.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5439</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2022-05711&amp;r=1</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/310</obo:IAO_0000233>
        <obo:OGG_0000000006>925</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5439</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD8A</rdfs:comment>
        <rdfs:label>Brachyury-expressing Modified Vaccinia Ankara-TRICOM Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007332</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine comprised of brain tumor initiating cells (BTICs), with potential immunostimulating and antineoplastic activity. BITCs are from the glioblastoma multiforme (GBM) cell line GBM-6 and contain glioma stem-like cell-associated antigens. Upon administration, the BITC vaccine may stimulate a specific anti-tumoral cytotoxic T-lymphocyte (CTL) response against brain tumor cancer cells and brain tumor stem like cells, resulting in tumor cell lysis. BITC have unique antigenicity and have the ability to self-renew; vaccination against BITC antigens may kill these cells and may prevent tumor recurrences.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5210</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/311</obo:IAO_0000233>
        <obo:OGG_0000000006>3383</obo:OGG_0000000006>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:OGG_0000000006>965</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5210</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD58</rdfs:comment>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:comment>Gene name: ICAM1</rdfs:comment>
        <rdfs:label>Brain Tumor Initiating Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007333 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007333">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007333</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of recombinant modified vaccinia Ankara (rMVA) encoding the prostate specific antigen (PSA), the prostate-specific membrane antigen (PSMA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). Vaccination with PSA/PSMA in combination with TRICOM may enhance antigen presentation, resulting in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells over-expressing PSA or PSMA.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&amp;code=C29561</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5309</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/312</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5309</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>rMVA-PSA/PSMA/TRICOM vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007334">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007334</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) that encodes the gene for human interleukin-12 (hIL-12). Produced mainly by B-cells, IL-12 is an endogenous cytokine that activates natural killer (NK) cells, promotes cytotoxic T lymphocyte (CTL) responses, induces the release of interferon-gamma (IFN-gamma), and may exhibit antitumor and anti-angiogenic effects. Vaccination with canarypox-hIL-12 melanoma vaccine may stimulate the host immune system to mount an immune response against tumor cells, thereby inhibiting tumor growth and/or metastasis.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5544</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/313</obo:IAO_0000233>
        <obo:OGG_0000000006>2521</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5544</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FUS</rdfs:comment>
        <rdfs:label>Canarypox-hIL-12 melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007335 -->

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        <obo:IAO_0000115>A cancer vaccine that uses dendritic cells pulsed with autologous tumor homogenate in combination With High Dose-IL2 and immunomodulating radiotherapy for patients with Metastatic RCC.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03226236</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6266</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6266</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autolgous DC vaccine pulsed with autologous tumor homogenate for metastatic rcc</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007336 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007336</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that  consists of of irradiated autologous tumor cells admixed with GM-CSF-secreting bystander cells. The CD8+ T cells can react against CLL-associated antigens. Autologous tumor cell vaccination is an effective strategy to advance long-term leukemia control following allogeneic hematopoietic stem cell transplantation (allo-HSCT). </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:23912587</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6379</obo:IAO_0000119>
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        <obo:VO_0001818>6379</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous CLL tumor cell vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007337 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007337</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that uses autologous cancer testis (CT) antigen specific dendritic cell (DC) preceded by decitabine as a demethylating chemotherapy for patients with high-risk neuroblastoma, Ewings sarcoma, osteogenic sarcoma, rhabdomyosarcoma or synovial sarcoma. The mature DC is pulsed with overlapping peptides mixes derived from full-length NY-ESO-1, MAGE-A1, and MAGE-A3.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01241162</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6268</obo:IAO_0000119>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
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        <obo:VO_0001818>6268</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGE-A1</rdfs:comment>
        <rdfs:comment>Gene name: MAGE-A3</rdfs:comment>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>autologous cancer testis antigen specific dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007338 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007338</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous dendritic cells (DCs) loaded with mRNA encoding the human cytomegalovirus (CMV) matrix protein pp65 (65 kDa lower matrix phosphoprotein; UL83) as a fusion protein with the full-length lysosome-associated membrane protein (flLAMP), with potential immunostimulatory and antineoplastic activities. The vaccine exposes the immune system to the CMV pp65 peptide, which may elicit a cytotoxic T-lymphocyte (CTL) response against CMV pp65-expressing tumor cells. The incorporation of flLAMP may route CMV pp-65 antigens into the lysosomal compartment, resulting in enhanced MHC class II antigen presentation, thereby promoting CD4-positive T-cell responses. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a powerful adjuvant capable of stimulating macrophage function, inducing proliferation and maturation of DCs, and is able to enhance T-lymphocyte stimulatory function. The vaccine can be used in combination with monoclonal antibodies, such as basiliximab, that can block tumor growth in different ways, as well as temozolomide, and radiation therpay. The combination of treatments may kill more tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C156067</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00626483</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6347</obo:IAO_0000119>
        <obo:OGG_0000000006>27074</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6347</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: LAMP</rdfs:comment>
        <rdfs:label>autologous CMV-pp65-flLAMP mRNA loaded dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007339 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007339</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made of dendritic cells (DCs) loaded with personalized peptides (PEP) given in combination with low-dose cyclophosphamide for patients with advanced or recurrent metastatic NSCLC.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05195619</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6267</obo:IAO_0000119>
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        <obo:VO_0001818>6267</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous dendritic cell vaccine loaded with personalized peptide vaccine (pep-dc vaccine)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007340 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007340</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that encodes macrophage inflammatory protein 3 alpha (MIP3a)-fused lymphoma idiotype in single chain format for patients with atients with Asymptomatic Phase Lymphoplasmacytic Lymphoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6264</obo:IAO_0000119>
        <obo:OGG_0000000006>6364</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6264</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MIP3a</rdfs:comment>
        <rdfs:label>autologous lymphoma immunoglobulin-derived scFv-chemokine DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007341 -->

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        <obo:IAO_0000115>A cancer vaccine that uses autologous neuroblastoma cells, irradiated and genetically modified by adenoviral vectors to secrete interleukin-2 (IL-2) for patients with high-risk neuroblastoma. The adenoviral vector are used to transduce the cells ex-vivo, patients are not treated with the viral vector.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00048386</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6269</obo:IAO_0000119>
        <obo:OGG_0000000006>3558</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6269</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IL-2</rdfs:comment>
        <rdfs:label>autologous neuroblastoma cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007342 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007342</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is composed of oxidized ovarian tumor cell lysate, with potential immunostimulatory and antineoplastic activities. The autologous oxidized ovarian tumor cell lysate vaccine exposes the immune system to an undefined amount of tumor-associated antigens (TAAs), which may result in the induction of both anti-tumor cytotoxic T-lymphocytes (CTLs) and antibody-dependent responses against TAA-expressing cells, leading to tumor cell lysis. Compared to non-oxidized tumor cell lysate vaccines, oxidized tumor cell lysate vaccines induce necrotic cell death, increase the immunogenicity of the TAAs and may enhance the anti-tumor immune response. Cyclophosphamide/Fludarabine Lymphodepletion and an immunomodulatory combination of Interferon-alpha Bevacizumab and Aspirin followed by adoptive transfer of vaccine-primed ex vivo CD3/CD28-costimulated peripheral blood autologous T cells and vaccination with whole tumor vaccine administered intradermally in combination with Bevacizumab in patients with recurrent ovarian cancer fallopian tube or primary peritoneal cancer may help treat their tumors. Patients will receive 5-10 million cells intradermally. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C122402</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: [https://clinicaltrials.gov/study/NCT01312376</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6330</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6330</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous oxidized ovarian tumor cell lysate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007343 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007343</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of total tumor RNA (TTRNA) derived and amplified from autologous tumor cells and mRNA encoding the human cytomegalovirus (CMV) matrix protein pp65 (65 kDa lower matrix phosphoprotein; UL83) as a fusion protein with the full-length lysosome-associated membrane protein (flLAMP), formulated in DOTAP lipid particles, with potential immunostimulatory and antineoplastic activities. he autologous total tumor mRNA and CMV-pp65-flLAMP mRNA loaded liposome vaccine, the mRNA is taken up, translated and presented by antigen presenting cells (APCs). This leads to an induction of both cytotoxic T-lymphocyte and memory T-cell dependent immune responses that specifically target and destroy the patient&apos;s cancer cells that express these tumor antigens. The incorporation of flLAMP may route CMV pp-65 antigens into the lysosomal compartment, resulting in enhanced MHC class II antigen presentation, thereby promoting CD4-positive T-cell responses. Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liposome vaccine is used to treat patients with Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM). The vaccine is also used for for the treatment of early melanoma recurrence following adjuvant Anti-PD-1 antibody therapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C178432</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04573140</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05264974</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6270</obo:IAO_0000119>
        <obo:OGG_0000000006>27074</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
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        <obo:VO_0001818>6270</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: LAMP</rdfs:comment>
        <rdfs:label>autologous total tumor mrna and CMV-pp65-flLAMP mRNA loaded liposome vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007344 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007344</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made from the patient&apos;s cancer cells that may make the body build an immune response and kill their tumor cells. The autologous tumor cell vaccine will be given together with adjuvant interferon gamma or sargramostim (GM-CSF) in patients with advanced cancer (breast, lung, prostate, colorectal, sarcoma, renal, melanoma). The vaccine uses irradiated autologous tumor cells and tumor lysate.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00002505</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6364</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6364</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous tumor cell lysate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007345 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007345">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007345</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made from the patient&apos;s own tumor tissue may stimulate an immune response against the patient&apos;s tumor cells. O-Vax nay induce a DTH response to autologous, DNP-modified ovarian cancer cells. The vaccine includes DNP-modified autologous ovarian tumor cells followed by cyclophosphamide then weekly doses of DNP-modified autologous ovarian tumor cells mixed with Bacillus of Calmette and Guérin (BCG).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00660101</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6334</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6334</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous, dnp-modified ovarian cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007346 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007346</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing human acute myeloid leukemic (AML) blasts that have been genetically engineered to express a B7.1/IIL-2 fusion protein. It uses B7.1 (CD80)/IL-2 immune gene therapy for high risk MDS RAEB-2 and acute myeloid leukaemia (AML) patients who are unsuitable for an allogeneic haematological stem cell transplant.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02493829</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6265</obo:IAO_0000119>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6265</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: B7.1</rdfs:comment>
        <rdfs:label>B7.1/​IL-2 leukaemia cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007347 -->

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        <obo:IAO_0000115>A cancer vaccine made with BC-819 (also known as DTA-H19), which is a double-stranded DNA plasmid, 4,560 base pairs (bp) in length, carrying the gene for the Diphtheria toxin A (DT-A) chain under the regulation of the H19 promoter. The DT-A chain expression is triggered by the presence of H19 transcription factors that are only up-regulated in tumor cells. The selective initiation of toxin expression results in selective tumor cell destruction via inhibition of protein synthesis selectively in the tumor cell, enabling highly targeted cancer treatment. It is used in combination with intravenously administered gemcitabine for patients with Locally Advanced Pancreatic Adenocarcinoma. The activation of the H19 gene promoter-containing plasmids and DTA expression are limited to tumor cells, as high levels of H19 expression are only found in tumor cells. DTA disrupts protein synthesis. Tumor-cell selective expression of this toxin leads to the selective destruction of the tumor while sparing healthy, normal cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C107685</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01413087</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6273</obo:IAO_0000119>
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        <obo:VO_0001818>6273</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>BC-819 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007348 -->

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        <obo:IAO_0000115>A cancer vaccine made up of Bcl-xl_42 and the adjuvant CAF09b for patients with hormone-sensitive Prostate Cancer (PC) and lymph node metastases. B-cell lymphoma extra large protein (Bcl-xl) protein plays a vital role in the cancer cell&apos;s ability to avoid programmed cell death (apoptosis) and is upregulated in a variety of cancerous diseases, Bcl-xl_42 is a peptide fragment of the full protein and can lead to the death of cancer cells. CAF09b improves the activation of the immune system. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03412786</obo:IAO_0000119>
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        <obo:VO_0001818>6272</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Bcl-Xl_42-CAF09b vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007349 -->

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        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:/7629885</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5329</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/372</obo:IAO_0000233>
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        <obo:VO_0001818>5329</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>CAP-2 (CEA peptide 9-mer) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007350 -->

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        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5380</obo:IAO_0000119>
        <obo:IAO_0000119>https://link.springer.com/article/10.1007/s11888-014-0250-5</obo:IAO_0000119>
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        <obo:VO_0001818>5380</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>CAP-3 (CEA Peptide 9-mer) Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007351 -->

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        <obo:IAO_0000115>9-residue human leukocyte antigen (HLA)-restricted fragment of carcinoembryonic antigen (CEA). Vaccination with carcinoembryonic antigen peptide 1-6D, which has the amino acid sequence YLSGANLNL, may elicit a cytotoxic T lymphocyte (CTL) immune response against tumors expressing CEA.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5356</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/374</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
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        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>Carcinoembryonic Antigen Peptide 1-6D Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007352 -->

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        <obo:IAO_0000115>A cancer vaccine, consisting of alphavirus vector-derived virus-like replicon particles expressing the 9-amino-acid carcinoembryonic antigen peptide (CAP) 1-6D, with potential antineoplastic activity. Vaccination with this agent may elicit a cytotoxic T lymphocyte (CTL) immune response against CEA-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5129</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/375</obo:IAO_0000233>
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        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>carcinoembryonic antigen peptide 1-6D virus-like replicon particles vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007353 -->

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        <obo:IAO_0000115>A cancer vaccine comprised of an epitope from the Carcinoembryonic Antigen obtained from cancer cells that can stimulate an immune response against tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22630596</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5209</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/376</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5209</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>carcinoembryonic antigen peptide-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007354 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007354</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine comprised of autologous dendritic cells pulsed with mRNA-encoded Carcinoembryonic Antigen (CEA) targeting tumor cells expressing CEA. </obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:21187495</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5041</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/377</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5041</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>Carcinoembryonic Antigen RNA-pulsed DC Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007355 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007355</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of the bcr-abl b2a2 fusion oncoprotein, frequently expressed in chronic myelogenous leukemia (CML), with potential antineoplastic activity. Vaccination with the bcr-abl (b2a2)-derived peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express the bcr-abl b2a2 fusion protein. (NCIT_C61309) The vaccine is made from made from the proteins that cause leukemia cells in CML to behave abnormally. Imatinib mesylate is the standard therapy for CML and blocks the function of this protein. In combination, these may decrease or eliminate all evidence of disease in patients who have CML that is in remission after treatment with imatinib mesylate, but who still have small amounts of detectable disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C61309</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00267085</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6353</obo:IAO_0000119>
        <obo:OGG_0000000006>25</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6353</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: bcr-abl</rdfs:comment>
        <rdfs:label>Bcr-Abl (b2a2)-derived peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007356 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007356</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA vaccine containing the mammalian expression vector pUMVC3 (pNGVL3) encoding epitopes of CD105 (Endoglin), Y-box binding protein 1 (Yb-1), SRY-box 2 (SOX2), cadherin 3 (CDH3), and murine double minute 2 (MDM2) proteins, with potential immunomodulating and antineoplastic activities. Upon intradermal administration of pUMVC3-CD105/Yb-1/SOX2/CDH3/MDM2-epitopes plasmid DNA vaccine, the plasmid transfects cells and the peptides are expressed. This generates a specific memory Th1 (T-helper) cell immune response, stimulates secretion of cytokines by the T cells and leads to a cytotoxic T-lymphocyte (CTL) response against CD105/Yb-1/SOX2/CDH3/MDM2-expressing tumor cells. CD105/Yb-1/SOX2/CDH3/MDM2 proteins are highly immunogenic tumor associated antigens that are overexpressed in breast cancer. Additionally, these antigens are associated with breast cancer stem cells and with epithelial to mesenchymal transformation (EMT).</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5193</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/379</obo:IAO_0000233>
        <obo:OGG_0000000006>1001</obo:OGG_0000000006>
        <obo:OGG_0000000006>2022</obo:OGG_0000000006>
        <obo:OGG_0000000006>4193</obo:OGG_0000000006>
        <obo:OGG_0000000006>4904</obo:OGG_0000000006>
        <obo:OGG_0000000006>6657</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5193</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CDH3</rdfs:comment>
        <rdfs:comment>Gene name: ENG</rdfs:comment>
        <rdfs:comment>Gene name: MDM2</rdfs:comment>
        <rdfs:comment>Gene name: SOX2</rdfs:comment>
        <rdfs:comment>Gene name: YBX1</rdfs:comment>
        <rdfs:label>CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007357 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007357">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007357</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted peptides derived from the CD133 antigen, with potential antineoplastic activity. Upon intradermal administration, the CD133 antigen peptide-pulsed autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against CD133-expressing tumor cells, resulting in tumor cell lysis. CD133, a cancer stem cell marker, is expressed on hematopoietic stem and progenitor cells and overexpressed on many types of cancer cells; it is associated with resistance to chemotherapy and increased cancer survival. HLA-A2 is an MHC class I molecule that presents antigenic peptides to CD8+ T-cells. Epitope design that is restricted to those epitopes that bind most efficiently to HLA-A2 may improve antigenic peptide immunogenicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT02049489</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5107</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/380</obo:IAO_0000233>
        <obo:OGG_0000000006>8842</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
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        <obo:VO_0001818>5107</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PROM1</rdfs:comment>
        <rdfs:label>CD133 Antigen Peptide-pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007358 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007358</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine comprised of CD80-transfected allogenic breast cancer cells to induce T-cell response.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5476</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/381</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5476</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD80</rdfs:comment>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>CD80 Breast Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007359 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007359</metadata:prefixIRI>
        <obo:IAO_0000115>Autologous human dendritic cells pulsed with RNA encoding the carcinoembryonic antigen (CEA) are being studied for possible use in the treatment of cancer expressing CEA.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:21187495</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5045</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/382</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5045</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>CEA RNA-pulsed Autologous Human Cultured Dendritic Cells Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007360 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007360</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid vaccine encoding wild type human carcinoembryonic antigen (CEA) fused to a tetanus toxoid T helper epitope, with potential antineoplastic activity. Upon vaccination and subsequent intradermal electroporation, CEA/tetanus toxoid T helper epitope fusion protein-expressing DNA plasmid vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells. CEA, a tumor associated antigen, is overexpressed in a variety of cancer cell types. The tetanus toxoid helper peptide epitope, obtained from the bacterial Clostridium tetani toxoid, binds to class II MHC molecules and increases the helper T-cell response thereby inducing an increased and long-term immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5367</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/383</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
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        <obo:VO_0001818>5367</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>CEA/Tetanus Toxoid T Helper Epitope Fusion Protein-Expressing DNA Plasmid Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007361 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007361</metadata:prefixIRI>
        <obo:IAO_0000115>A complex, replication-selective, E1B and partial E3 gene deleted, adenovirus type 11p (Ad11p)/Ad3 chimeric oncolytic virus with potential antineoplastic activity. Upon intralesional injection of enadenotucirev, the adenovirus selectively and rapidly replicates in cancer cells; however, it is unable to replicate in normal, healthy cells. This induces a selective adenovirus-mediated cytotoxicity in cancer cells, which leads to cancer cell lysis. Following the lysis of infected cells, the replicated virus is released and can infect adjacent cells, which both induces further tumor cell oncolysis and may activate the immune system to kill the infected tumor cells. The E1B protein causes p53 inactivation in host cells, which promotes viral replication. Deletion of E1B prevents replication in normal, healthy cells that express wild-type p53. The mutation and subsequent inactivation of p53 in cancer cells enables the E1B-deleted adenovirus to selectively replicate in cancer cells. Partial deletion of the E3 gene, which encodes the adenovirus death protein, enhances the safety profile of the administered adenovirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5316</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(05)00564-2</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/384</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5316</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Chimeric Ad11p/Ad3 Oncolytic Virus Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007362 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007362</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with the human cytomegalovirus (CMV) phosphoprotein pp65, with potential immunostimulatory and antineoplastic activities. Upon administration, the CMV pp65 peptide-pulsed autologous DC vaccine exposes the immune system to the CMV pp65 peptide, which may result in a cytotoxic T-lymphocyte (CTL) response against CMV pp65-expressing tumor cells leading to cell lysis. The CMV pp65 protein, also called the 65 kDa lower matrix phosphoprotein, is the primary component of the enveloped subviral particle of CMV and is expressed in certain tumor types, such as glioblastoma</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4985</obo:IAO_0000119>
        <obo:IAO_0000119>https://academic.oup.com/neuro-oncology/article/22/Supplement_3/iii306/6018727</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/385</obo:IAO_0000233>
        <obo:OGG_0000000006>3077579</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>4985</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: UL83</rdfs:comment>
        <rdfs:label>CMV pp65 Peptide-pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007363 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007363">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007363</metadata:prefixIRI>
        <obo:IAO_0000115>A poloxamer-formulated, bivalent DNA vaccine containing two plasmids encoding both the human cytomegaloviral (CMV) tegument phosphoprotein 65 (pp65), a major internal matrix protein, and glycoprotein B (gB), an important CMV component responsible for attachment and entry into cells, with potential immunostimulatory properties. Upon intramuscular injection of CMVpp65/gB plasmid vaccine ASP0113, the expressed proteins may activate the immune system to mount both cellular and humoral immune responses against CMV-positive cells. This results in cell lysis of CMV-infected cells and prevents both viral replication and the development of CMV disease. This vaccine also provides active immunization and protective immunity against CMV infection in CMV-negative patients exposed to infected donor cells or tissues in transplant recipients. CMV infection can cause serious complications in patients receiving either allogeneic hematopoietic cell transplants (HCT) or solid organ transplants. The poloxamer-based delivery system enhances DNA delivery.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5306</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/386</obo:IAO_0000233>
        <obo:OGG_0000000006>3077579</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
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        <obo:VO_0001818>5306</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: UL83</rdfs:comment>
        <rdfs:label>CMVpp65/gB plasmid vaccine ASP0113</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007364 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007364</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of the bcr-abl b2a2 fusion oncoprotein, frequently expressed in chronic myelogenous leukemia (CML), with potential antineoplastic activity. Vaccination with the bcr-abl (b2a2)-derived peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express the bcr-abl b2a2 fusion protein. The vaccine is made from made from the proteins that cause leukemia cells in CML to behave abnormally. Imatinib mesylate is the standard therapy for CML and blocks the function of this protein. In combination, these may decrease or eliminate all evidence of disease in patients who have CML that is in remission after treatment with imatinib mesylate, but who still have small amounts of detectable disease.  </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C61310</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00466726</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6274</obo:IAO_0000119>
        <obo:OGG_0000000006>25</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6274</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: bcr-abl</rdfs:comment>
        <rdfs:label>Bcr-Abl (b3a2)-derived peptide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007365 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007365</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine composed of synthetic peptides derived from beta-human chorionic gonadotropin (hCG) conjugated to diphtheria toxoid. Vaccination with this peptide may elicit the host immune response against hCG-producing cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:/9815634</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5372</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/389</obo:IAO_0000233>
        <obo:OGG_0000000006>11716682</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5372</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: tox1</rdfs:comment>
        <rdfs:label>CTP-37-DT vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007366 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007366</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with cyclin B1 peptide, with potential immunostimulatory and antineoplastic activities. Upon administration, cyclin B1 peptide-pulsed autologous dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and anti-cyclin B1 antibody responses against cyclin B1-expressing cancer cells, resulting in tumor cell lysis. Cyclin B1, a key regulator of the cell cycle and cell division, is overexpressed in a variety of cancer cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT01398124</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5139</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/390</obo:IAO_0000233>
        <obo:OGG_0000000006>931</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5139</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MS4A1</rdfs:comment>
        <rdfs:label>Cyclin B1 Peptide-pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007367 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007367</metadata:prefixIRI>
        <obo:IAO_0000115>A preparation of autologous lymphocytes with potential immunopotentiating and antineoplastic activities. Cytokine-induced killer (CIK) cells are CD3- and CD56-positive, non-major histocompatibility complex (MHC)-restricted, natural killer (NK)-like T lymphocytes, generated ex-vivo by incubation of peripheral blood lymphocytes (PBLs) with anti-CD3 monoclonal antibody, interleukin (IL)-2, IL-1, and interferon gamma (IFN-gamma) and then expanded. When reintroduced back to patients after autologous stem cell transplantation, CIK cells may recognize and kill tumor cells associated with minimal residual disease (MRD). CIK cells may have enhanced cytotoxic activity compared to lymphokine-activated killer (LAK) cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:23210562</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5070</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/391</obo:IAO_0000233>
        <obo:OGG_0000000006>174</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5070</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: AFP</rdfs:comment>
        <rdfs:label>Cytokine-Induced Killer Cells Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007368 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007368</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine composed of dendritic cells pulsed with tumor cells lysates that stimulate a potent and specific cell mediated anti-tumor immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15256471</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5163</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/392</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5163</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Dendritic Cell Tumor Cell Lysate Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007369 -->

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        <obo:IAO_0000115>A cancer vaccine consisting of lymphocytes harvested from a patient with lung cancer and induced to become antigen-presenting cells (APCs) known as dendritic cells. The dendritic cells are transduced with the gene encoding an antigen specific to the patient&apos;s cancer and then returned to the patient. In the host, the altered cells stimulate the immune system to mount a primary T cell response against lung tumor cells expressing the target antigen. Dendritic cell-autologous lung tumor vaccines have been investigated for use in cancer immunotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5161</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/393</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5161</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Dendritic Cell-Autologous Lung Tumor Vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007370 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007370</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of dendritic cells harvested from a patient with cancer and pulsed or transduced with a peptide fragment of carcinoembryonic antigen (CEA), a tumor-associated antigen expressed by a wide range of cancers. When the altered dendritic cells are returned to the patient, they may stimulate the host immune system to mount a cytotoxic T-lymphocyte immune response against tumor cells expressing CEA.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:21187495</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5417</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/394</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
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        <obo:VO_0001818>5417</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5 (CEA)</rdfs:comment>
        <rdfs:label>Dendritic Cell-CEA Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007371 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007371</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous dendritic cells vaccine with antineoplastic property. Dendritic cells harvested from cancer patients are pulsed with human gp100 melanoma antigen and MART-1 (melanoma antigen recognized by T-cells) antigen; both antigens are up-regulated in melanomas. Vaccination with this vaccine may elicit the host immune response against MART-1 or gp100 expressing cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5067</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/395</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5067</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: gp100 (PMEL)</rdfs:comment>
        <rdfs:label>dendritic cell-gp100-MART-1 Antigen vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007372 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007372</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of dendritic cells harvested from a patient with cancer and pulsed or transduced with a peptide fragment of MART-1 (melanoma antigen recognized by T-cells), an antigen expressed by melanoma cells. When the altered dendritic cells are returned to the patient, they stimulate the host immune system to mount a cytotoxic T-lymphocyte immune response against tumor cells expressing MART-1.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5524</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/396</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5524</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:label>dendritic cell-MART-1 Peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007373 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007373</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine comprised of autologous dendritic cells pulsed with a recombinant prostate specific membrane antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5000</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/397</obo:IAO_0000233>
        <obo:OGG_0000000006>2346</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5000</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Prostate-specific membrane antigen gene engineering:</rdfs:comment>
        <rdfs:label>Dendritic Cell-Recombinant Prostate-Specific Membrane Antigen Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007374 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007374</metadata:prefixIRI>
        <obo:IAO_0000115>An engineered lentiviral vector targeting dendritic cells (DCs) and containing nucleic acids encoding for the human tumor-associated cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, the DC-targeting lentiviral vector ID-LV305 targets and binds to dermal DCs via the DC-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) receptor. Upon internalization of the vector, the NY-ESO-1 protein is expressed, stimulates DC maturation and activates the immune system to mount a cytotoxic T-lymphocyte (CTL) response against NY-ESO-1-expressing cells, which may result in tumor cell lysis. NY-ESO-1 is expressed in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5493</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2018-00926&amp;r=1</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/398</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5493</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>Dendritic Cell-targeting Lentiviral Vector ID-LV305 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007375 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007375</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous renal cell carcinoma (RCC) tumor cells modified with the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of DNP-modified autologous renal cell carcinoma tumor cell vaccine may induce a cytotoxic T-lymphocyte (CTL) response against renal cell carcinoma tumor cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5338</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/400</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5338</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Dinitrophenyl-Modified Autologous Renal Cell Carcinoma Tumor cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007376 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007376</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA vaccine encoding the human pro-inflammatory cytokine interleukin-12 (IL-12) with potential immunoactivating activity. Upon intramuscular delivery by electroporation of DNA plasmid encoding interleukin-12 INO-9012, IL-12 is translated in cells and activates the immune system by promoting the activation of natural killer cells (NK cells), inducing secretion of interferon-gamma and promoting cytotoxic T-cell responses against tumor cells. This may result in both immune-mediated tumor cell death and the inhibition of tumor cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>DNA Plasmid Encoding Interleukin-12 INO-9012 Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5016</obo:IAO_0000119>
        <obo:IAO_0000119>https://jitc.bmj.com/content/9/7/e003019</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/401</obo:IAO_0000233>
        <obo:OGG_0000000006>2902</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5016</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GRIN1</rdfs:comment>
        <rdfs:label>DNA plasmid-encoding Interleukin-12 INO-9012 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007377 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007377</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA-based combination immunotherapeutic, INO-3112, composed of VGX-3100, a preparation of DNA plasmids encoding the E6 and E7 genes of human papillomavirus (HPV) subtypes 16 and 18, combined with INO-9012, a DNA plasmid encoding the immune activator and pro-inflammatory cytokine human interleukin-12 (IL-12) with potential immunoactivating and antineoplastic activities. Upon intramuscular delivery by electroporation of VGX-3100, the HPV E6 and E7 proteins are translated in cells and elicit a cytotoxic T-lymphocyte (CTL) response against cancer cells expressing the E6 and E7 antigens, resulting in tumor cell lysis. HPV type 16 and HPV type 18 are associated with the development of certain types of cancer. Upon intramuscular delivery by electroporation of INO-9012, IL-12 is expressed and activates the immune system by promoting the activation of natural killer cells (NK cells), inducing secretion of interferon-gamma (IFN-g) and promoting CTL responses against tumor cells. This boosts the immune response and results in increased CTL-mediated tumor cell death as compared with the administration of VGX-3100 alone.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT03439085</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5136</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/402</obo:IAO_0000233>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5136</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>DNA plasmid-encoding Interleukin-12/HPV DNA plasmids therapeutic vaccine INO-3112</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007378 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007378</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic DNA vaccine composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type 16 (HPV16), the second is a dimerization entity and the third part encodes a protein that specifically binds to antigen presenting cells (APCs), with potential immunostimulating and antineoplastic activities. Upon intramuscular administration, the DNA vaccine VB10.16 expresses HPV16 E6/7 and a protein that targets receptors on APCs. Upon binding to APCs and subsequent internalization, the APCs mature and the HPV16 E6/7 antigenic protein is presented by the APCs. This attracts and stimulates B-lymphocytes, CD4-positive T-lymphocytes and elicits a cytotoxic T-lymphocyte (CTL) response against cancer cells expressing HPV16-associated E6 and E7 oncoproteins, which result in tumor cell lysis. HPV16 E6/7, a viral antigen, plays a key role in the development of certain types of cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:36129459</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5207</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/403</obo:IAO_0000233>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5207</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>DNA Vaccine VB10.16</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007379 -->

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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007379</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a DNA plasmid encoding epitopes of the human preferential antigen of melanoma (PRAME) and the prostate specific membrane antigen (PSMA) with potential immunostimulating activity. Upon direct administration of this vaccine into lymph nodes, peptides expressed by DNA plasmid vector pPRA-PSM may activate the immune system, resulting in a cytotoxic T-lymphocyte (CTL) response against PRAME- and PSMA-expressing cells. PRAME and PSMA are tumor associated antigens upregulated in a number of cancer cell types. As part of the MKC1106-PP regimen exploiting the &apos;prime-boost strategy&apos;, this plasmid is responsible for priming the immune response and is used in conjunction with a peptide vaccine consisting of PRAME and PSMA that boosts the immune system against PRAME- and PSMA-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00423254</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5407</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/404</obo:IAO_0000233>
        <obo:OGG_0000000006>2346</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5407</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Prostate-specific membrane antigen</rdfs:comment>
        <rdfs:label>DNA vector pPRA-PSM vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007380 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007380</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a recombinant fowlpox viral vector encoding the carcinoembryonic antigen (CEA), MUC-1, a transmembrane glycoprotein secreted by glandular epithelial tissues, and TRICOM, comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3). This agent may enhance CEA and MUC-1 presentation to antigen-presenting cells (APC) and may activate a cytotoxic T-cell response against CEA- and MUC-1-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5378</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/126</obo:IAO_0000233>
        <obo:OGG_0000000006>	4582</obo:OGG_0000000006>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5378</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>Falimarev vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007381 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007381">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007381</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic cancer vaccine containing a truncated, synthetic peptide mimic of the human angiogenic activator vascular endothelial growth factor (VEGF), consisting of 79 amino acids (amino acids 26-104 of VEGF), and emulsified in the immunoadjuvant RFASE, with potential immunostimulatory and antitumor activities. Upon intramuscular vaccination, the hVEGF26-104 moiety of hVEGF26-104/RFASE acts as an antigen and induces an immune response against VEGF, which results in anti-VEGF antibody binding to and neutralization of endogenous VEGF. This prevents the binding of endogenous VEGF to the VEGF receptor (VEGFR) and blocks VEGFR-mediated endothelial cell signaling, resulting in an inhibition of both angiogenesis and tumor cell proliferation. VEGF plays a key role in angiogenesis, tumor cell proliferation and invasion. RFASE, which belongs to the group of sulpholipopolysaccharides (SLPs), is a synthetic polysaccharide covalently coupled to lipid groups and sulphate groups, and is able to induce a strong humoral immune response upon antigen administration.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5090</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/456</obo:IAO_0000233>
        <obo:OGG_0000000006>7422</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
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        <obo:VO_0001818>5090</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: VEGFA</rdfs:comment>
        <rdfs:label>hVEGF26-104/RFASE peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007382 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007382</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus subtype 6 (HPV-6), with potential immunostimulating and antineoplastic activities. Administered via intramuscular electroporation, HPV-6-targeting immunotherapeutic vaccine INO-3106 expresses the HPV-6 E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells that are expressing those proteins, resulting in tumor cell lysis. HPV-6 infections are associated with aerodigestive malignancies.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5464</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/438</obo:IAO_0000233>
        <obo:OGG_0000000006>2829163</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5464</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HPV6 E6</rdfs:comment>
        <rdfs:label>HPV-6-targeting immunotherapeutic vaccine INO-3106</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007383 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007383">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007383</metadata:prefixIRI>
        <obo:IAO_0000115>A liposome-encapsulated peptide vaccine consisting of a synthetic peptide derived from the mucin 1 (MUC-1) antigen with potential antineoplastic activity. Upon vaccination, MUC-1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against MUC-1-expressing tumor cells, resulting in growth inhibition. MUC-1 antigen is a high-molecular-weight transmembrane glycoprotein that is overexpressed on the cell surfaces of many epithelial tumor cells as well as on the cell surfaces of some B-cell lymphoma cells and multiple myeloma cells. (NCIT_C2195).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5103</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/65</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5103</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>Emepepimut-S vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007384 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007384">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007384</metadata:prefixIRI>
        <obo:IAO_0000115>An allogeneic urothelial bladder cancer cell vaccine expressing a recombinant secretory form of the immunoadjuvant heat shock protein gp96 fused with an immunoglobulin Fc domain (gp96-Ig) protein, with potential antineoplastic activity. Upon administration of the gp96-Ig-secreting allogeneic bladder cancer cell vaccine HS-410, the live, irradiated tumor cells continuously secrete gp96-Ig along with its chaperoned tumor associated antigens (TAAs). This enhances antigen cross presentation to cytotoxic T-lymphocytes (CTLs) and, upon expansion, leads to the induction of a potent CTL response against the TAAs on the endogenous bladder cancer cells. This vaccine also induces a memory T cell response that could fight recurring cancer cells. gp96-Ig is constructed by replacing the KDEL endoplasmic reticulum (ER) retention sequence of gp96 with the Fc portion of the IgG1 protein. This allows for gp96, normally an ER-resident chaperone peptide, to be released from cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5033</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/209</obo:IAO_0000233>
        <obo:OGG_0000000006>7184</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5033</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HSP90B1</rdfs:comment>
        <rdfs:label>gp96-secreting Allogeneic Bladder Cancer Cell Vaccine HS-410</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007385">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007385</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant fowlpox virus vector encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1, an antigen found in normal testis and various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. Vaccination with NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5300</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/131</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5300</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>fowlpox-NY-ESO-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007386">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007386</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of autologous dendritic cells pulsed with synthetic glioma-associated antigen (GAA) peptides with potential antineoplastic activity. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against GAA peptide-expressing glioma cells, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5096</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/137</obo:IAO_0000233>
        <obo:OGG_0000000006>2548</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5096</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GAA </rdfs:comment>
        <rdfs:label>Glioma-Associated Antigen Peptide-Pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007387 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007387">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007387</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various, synthetic glioma-associated antigen (GAA) peptides, with potential antineoplastic activity. Upon subcutaneous administration, the glioma-associated peptide-loaded DC vaccine SL-701 exposes the immune system to various GAA peptides. This may stimulate both anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against the GAA-expressing glioma cells, which may result in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5073</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/138</obo:IAO_0000233>
        <obo:OGG_0000000006>1956</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5073</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EGFR</rdfs:comment>
        <rdfs:label>Glioma-associated Peptide-loaded Dendritic Cell Vaccine SL-701</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007388 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007388</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5202</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/426</obo:IAO_0000233>
        <obo:OGG_0000000006>55553</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5202</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: SOX6</rdfs:comment>
        <rdfs:label>HLA-A2-Restricted Synthetic Glioma Antigen Peptides Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007389 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007389">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007389</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5298</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/458</obo:IAO_0000233>
        <obo:OGG_0000000006>3417</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5298</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IDH1</rdfs:comment>
        <rdfs:label>IDH1R132H Mutation-targeting IDH1 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007390 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007390">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007390</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine consisting of a peptide derived from isocitrate dehydrogenase 1 (IDH1) containing the point mutation R132H (IDH1R132H), with potential antineoplastic activity. Intradermal vaccination with the IDH1R132H-specific peptide vaccine PEPIDH1M may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express the IDH1R132H protein. The IDH1 point mutation of amino acid residue 132 is highly expressed in gliomas and is associated with increased production of the oncometabolite R-2-hydroxyglutarate</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5461</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/459</obo:IAO_0000233>
        <obo:OGG_0000000006>3417</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5461</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IDH1</rdfs:comment>
        <rdfs:label>IDH1R132H-Specific Peptide Vaccine PEPIDH1M</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007391 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007391">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007391</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from malignant glioma cells with potential immunostimulatory and antineoplastic activities. Upon administration, malignant glioma tumor lysate-pulsed autologous dendritic cell vaccine exposes the immune system to undefined malignant glioma tumor-associated antigens (TAAs), which may result in anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against glioma cells and glioma cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5215</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/494</obo:IAO_0000233>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5215</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA1</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007392 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007392">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007392</metadata:prefixIRI>
        <obo:IAO_0000115>An antineoplastic vaccine directed against a peptide found in the epidermal growth factor receptor class III variant (EGFRvIII), a constitutively activated mutant of the wild-type tyrosine kinase. This protein variant is present in a substantial proportion of malignant gliomas and other human cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5531</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/64</obo:IAO_0000233>
        <obo:OGG_0000000006>1100818972</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5531</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EGFR</rdfs:comment>
        <rdfs:label>EGFRvIII Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007393 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007393">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007393</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5151</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/127</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5151</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Fas-Chimera Transgene-expressing Endothelial Tumor Cell-targeting Adenovector VB-111 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007394 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007394">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007394</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with purified peptides derived from the tumor-associated antigen (TAA) CD133, with potential immunostimulatory and antineoplastic activities. Upon leukapheresis, monocytes are differentiated into DCs and are mixed with the CD133 peptides. Upon intradermal re-administration of the ICT-121 DC vaccine, the DCs present the CD133 peptides to the immune system, which stimulates the immune system to induce a specific cytotoxic T-lymphocyte (CTL) response against CD133-expressing tumor cells and leads to tumor cell lysis. CD133 is overexpressed on various types of cancer cells; its overexpression is correlated with increased resistance to chemotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5277</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/457</obo:IAO_0000233>
        <obo:OGG_0000000006>8842</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5277</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PROM1</rdfs:comment>
        <rdfs:label>ICT-121 Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007395 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007395">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007395</metadata:prefixIRI>
        <obo:IAO_0000115>A multivalent vaccine againt breast cancer that comprised of the epitope antigens of Globo H hexasaccharide 1 (Globo H), GM2 ganglioside, Lewis-Y, MUC1-32(aa), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin, with potential antineoplastic activity. The antigens included in this vaccine are associated various cancer cells. Vaccination with this multivalent vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5229</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/174</obo:IAO_0000233>
        <obo:OGG_0000000006>	4582</obo:OGG_0000000006>
        <obo:OGG_0000000006>2760</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5229</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM2A</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007396 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007396">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007396</metadata:prefixIRI>
        <obo:IAO_0000115>A dendritic cell (DC)-based cancer vaccine composed of autologous, type-1 polarized dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted HER-2-derived peptides, with potential immunomodulatory and antineoplastic activities. Autologous DCs were treated with GM-CSF, interleukin-4, interferon-gamma and bacterial lipopolysaccharide (LPS), a toll-like receptor type 4 agonist, to produce highly polarized DCs (alphaDC1) that are capable of producing high levels of interleukin-12p70 (IL-12p70). Upon administration, HER2-pulsed autologous DC vaccine may stimulate a potent cytotoxic T-lymphocyte (CTL) response against HER-2-positive tumor cells, which may result in tumor cell death and decreased tumor growth. HER-2, a tyrosine kinase receptor for epidermal growth factor (EGF) (also known as neu and ErbB2), is overexpressed by a variety of cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/306</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5237</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>HER2-pulsed Autologous Type-1 Polarized Dendritic Cell Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007397 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007397</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4997</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/447</obo:IAO_0000233>
        <obo:OGG_0000000006>1442</obo:OGG_0000000006>
        <obo:OGG_0000000006>7494</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4997</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CSH1</rdfs:comment>
        <rdfs:comment>Gene name: XBP1</rdfs:comment>
        <rdfs:label>hTERT/Survivin/CMV Multipeptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007398 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007398">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007398</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing a plasmid encoding the mammaglobin-A gene with potential immunostimulating and antineoplastic activities. Upon administration, mammaglobin-A DNA vaccine may induce both humoral and cytotoxic T lymphocyte (CTL) immune responses against tumor cells that express mammaglobin-A, which may result in decreased tumor growth. The 10 kiloDalton (kD) glycoprotein mammglobin-A is expressed in over 80% of human breast cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5166</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/495</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:OGG_0000000006>634</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5166</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM1</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>Mammaglobin-A DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007399 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007399">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007399</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor receptor 2 (HER2) with potential antineoplastic activity. Upon administration, modified vaccinia Ankara (Bavarian Nordic)-HER2 vaccine may stimulate the host immune system to mount humoral and cytotoxic T lymphocyte responses against HER2-expressing tumor cells, resulting in tumor cell lysis. HER2, also known as ErbB-2, is a tyrosine kinase growth factor receptor and a member of the epidermal growth factor receptor family; it plays a significant role in the pathogenesis of some breast cancers</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5036</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/530</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5036</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:comment>Gene name: MLANA-Dupli</rdfs:comment>
        <rdfs:label>Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007400 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007400">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005487"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007400</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of the bcr-abl b3a2 fusion oncoprotein, frequently expressed in chronic myelogenous leukemia (CML), with potential antineoplastic activity. Vaccination with the bcr-abl (b3a2)-derived peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express the bcr-abl b3a2 fusion protein. The bcr-abl p210-b3a2 breakpoint-derived pentapeptide vaccine is used in combination with GM-CSF. The peptides may help the body build an effective immune response to kill cancer cells, and the GM-CSF may increase the number of immune cells found in bone marrow or peripheral blood. This combination is used to treat patients with Philadelphia chromosome-positive chronic myelogenous leukemia. It can also be used in combination with imatinib mesylate to decrease or eliminate all evidence of disease in patients who have CML that is in remission after treatment with imatinib mesylate, but who still have small amounts of detectable disease</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C2205</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00004052</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00455221</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6372</obo:IAO_0000119>
        <obo:OGG_0000000006>25</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6372</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: bcr-abl</rdfs:comment>
        <rdfs:label>Bcr-Abl peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007401 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007401</metadata:prefixIRI>
        <obo:IAO_0000115>A proprietary lipid emulsion containing five vaccines: diphtheria, pertussis, tetanus (DPT), Bacille Calmette-Guerin (BCG), measles, Serratia marcescens and pneumococcal, with potential immunostimulating activity. Subcutaneous administration of the DPT/BCG/measles/Serratia/pneumococcus vaccine activates the immune system and may both abrogate tumor-induced immune tolerance and induce an antitumor immune response, which may eradicate the tumor. (NCIT_C62801).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4987</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/51</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4987</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>E1M(184V) peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007402 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007402</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing autologous dendritic cells (DCs) that are pulsed with mRNA encoding human telomerase reverse transcriptase (hTERT) and survivin peptide, with potential immunostimulatory and antineoplastic activities. Upon administration, hTERT mRNA/survivin peptide-double-loaded autologous dendritic cell vaccine may elicit an immune response against cancer cells expressing hTERT and survivin by activating cytotoxic T-cells (CTLs), natural killer cells (NKs), and B-lymphocytes. The tumor associated antigens (TAAs) hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types and play key roles in tumor cell growth and survival.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5121</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/440</obo:IAO_0000233>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5121</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>hTERT mRNA/survivin peptide-double-loaded autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007403 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007403">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007403</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic cancer vaccine consisting of four epitopes derived from the human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, including hTERT (540-548) acetate, hTERT (611-626) acetate, hTERT (672-686) acetate and hTERT (766-780) acetate, emulsified individually in the adjuvant montanide ISA-51 VG and administered with the immune response modifier (IRM) imiquimod, with potential immunostimulating and antineoplastic activities. Each hTERT peptide emulsion is administered individually by intradermal injection. Subsequently, imiquimod is applied topically to the injection site(s). Vaccination with GX 301 may elicit a cytotoxic T-cell (CTL) response against telomerase-expressing tumor cells. Telomerase is expressed in the majority of human cancer cells, infrequently expressed in normal cells, and is directly linked to tumorigenesis. Imiquimod stimulates cytokine production through the activation of toll-like receptor 7 (TLR-7), and also exhibits antiproliferative effects. Montanide ISA-51, also known as incomplete Freund&apos;s adjuvant (IFA), is a stabilized water-in-oil emulsion containing mineral oil with mannide oleate, which contains vegetable-grade (VG) oleic acid derived from olive oil. ISA-51 non-specifically stimulates cell-mediated immune responses to antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5516</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/441</obo:IAO_0000233>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5516</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>hTERT multipeptide/montanide ISA-51 VG/Imiquimod vaccine GX 301</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007404 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007404">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007404</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5065</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/445</obo:IAO_0000233>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5065</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>hTERT vaccine V934/V935</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007405 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007405">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000315"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007405</metadata:prefixIRI>
        <obo:IAO_0000115>A poxvirus made non-infectious by ultraviolet light or other inactivation methods in order to reduce its pathogenicity. In cancer gene therapy, inactivated vaccinia virus may be used as a vector to express a protein that kills tumor cells or elicits specific anti-tumor immunity. In a cancer vaccine application, tumor cells taken from the host may be adsorbed with inactivated vaccinia virus and returned to the host, where the modified tumor cells may stimulate an anti-tumor immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5130</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/465</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5130</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>inactivated vaccinia virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007406 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007406">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007406</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a recombinant vaccinia viral vector encoding the carcinoembryonic antigen (CEA), MUC-1 (mucin-1), a transmembrane glycoprotein secreted by glandular tissues, and TRICOM, comprised of the three co-stimulatory molecule transgenes B7-1, ICAM-1 and LFA-3. Upon administration, inalimarev may enhance CEA and MUC-1 presentation to antigen presenting cells (APC) and may activate a cytotoxic T lymphocyte (CTL) response against CEA- and MUC-1-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5099</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/466</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5099</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>inalimarev vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007407 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007407">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000367"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007407</metadata:prefixIRI>
        <obo:IAO_0000115>A proprietary, live-attenuated, double-deleted (LADD) strain of the Gram-positive bacterium Listeria monocytogenes (Lm) encoding multiple, as of yet undisclosed, tumor-associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, live-attenuated double-deleted Listeria monocytogenes bacteria JNJ-64041809 is taken up by antigen-presenting cells (APCs), including dendritic cells (DCs). The TAAs are subsequently expressed by the APCs and then processed and presented to the immune system by both major histocompatibility complex (MHC) class I and II molecules. This activates the immune system and leads to the recruitment and activation of cytotoxic T-lymphocytes (CTLs) against the TAA-expressing tumor cells, eventually resulting in tumor cell lysis. Two genes contributing to the virulence of Lm have been removed to minimize the risk of infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5258</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/472</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5258</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>live-attenuated double-deleted listeria monocytogenes bacteria JNJ-64041809 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007408 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007408</metadata:prefixIRI>
        <obo:IAO_0000115>A conjugate consisting of keyhole-limpet hemocyanin (KLH) and fluorescein isothiocyanate (FITC) with potential immunostimulating activity. Vaccination with KLH-FITC may elicit an immune response against fluorescein and the production of anti-fluorescein IgG antibodies. KLH, a natural protein isolated from the marine mollusk keyhole limpet, is an immunostimulant carrier protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5146</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/473</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5146</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>KLH-FITC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007409 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007409">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007409</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based vaccine targets tumors expressing the HER2/neu marker. HER-2/neu is a growth factor receptor, and its overexpression has been associated with a number of cancers including breast, ovarian, colon and lung cancers. APC8024 comprise of autologous antigen-presenting peripheral blood mononuclear cells (APCs) that have been exposed to HER2/neu protein and can be administered to the patient. These cells may stimulate an antitumor T-cell response to cancer cells expressing HER2/neu.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5538</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/475</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5538</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>Lapuleucel-T vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007410 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007410">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007410</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine consisting of autologous dendritic cells (DCs) pulsed with mesothelioma tumor lysate with potential immunostimulating and antineoplastic activities. Upon administration, mesothelioma tumor lysate-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount a specific cytotoxic T lymphocyte (CTL) response against mesothelioma tumor cells, resulting in tumor cell lysis. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5187</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/525</obo:IAO_0000233>
        <obo:OGG_0000000006>1234</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5187</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CCR5</rdfs:comment>
        <rdfs:label>mesothelioma tumor lysate-pulsed autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007411 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007411">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007411</metadata:prefixIRI>
        <obo:IAO_0000115>A cell wall fraction of bacillus Calmette-Guerin (BCG) obtained by menthol extraction with immunomodulating properties and potential use in cancer immunotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5235</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/526</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5235</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>methanol extraction residue of BCG</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007412 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007412">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007412</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5347</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/529</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5347</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: P10</rdfs:comment>
        <rdfs:label>Mimotope-P10s-PADRE peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007413 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007413">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007413</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of a monoclonal antibody (MoAb) directed against an idiotype that mimics a human milk fat globule (HMFG) membrane epitope. Vaccination with monoclonal antibody 11D10 anti-idiotype vaccine induces anti-anti-idiotype antibodies (Ab3) that may react with breast cancer cell lines expressing the HMFG membrane epitope.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5286</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/533</obo:IAO_0000233>
        <obo:OGG_0000000006>4240</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5286</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MFGE8</rdfs:comment>
        <rdfs:label>monoclonal antibody 11D10 anti-idiotype vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007414 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007414">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007414</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant monoclonal antibody in which the heavy and light chain variable domains mimic a specific epitope of the tumor-associated protein carcinoembryonic antigen (CEA). This agent is used as a cancer vaccine against tumors that express CEA.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5452</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/534</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
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        <obo:VO_0001818>5452</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:label>monoclonal antibody 3H1 anti-idiotype vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007415 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007415</metadata:prefixIRI>
        <obo:IAO_0000115>An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma, and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5308</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/536</obo:IAO_0000233>
        <obo:OGG_0000000006>2583</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5308</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: B4GALNT1</rdfs:comment>
        <rdfs:label>monoclonal antibody A1G4 anti-idiotype vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007416 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007416</metadata:prefixIRI>
        <obo:IAO_0000115>An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma, and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5469</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/537</obo:IAO_0000233>
        <obo:OGG_0000000006>6489</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5469</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ST8SIA1</rdfs:comment>
        <rdfs:label>monoclonal antibody GD2 anti-idiotype vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007417 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007417</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5239</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/538</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5239</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Montanide ISA-51/survivin peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007418 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007418">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007418</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5362</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/544</obo:IAO_0000233>
        <obo:OGG_0000000006>4255</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5362</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MGMT</rdfs:comment>
        <rdfs:label>MSCV-MGMT(P140K) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007419 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007419">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007419</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a synthetic peptide derived from the mucin 1 (MUC1) antigen with potential antineoplastic activity. Upon administration, MUC1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the MUC1 antigen, resulting in decreased tumor growth. Overexpressed on many tumor cells, MUC1 antigen, a mammary-type apomucin, is a high-molecular-weight transmembrane glycoprotein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5517</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/545</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5517</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>MUC-1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007420 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007420">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007420</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine containing human mucin 2 (MUC2) protein conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. MUC2, a secretory or gel forming glycoprotein expressed predominantly in goblet cells of the gastrointestinal and respiratory tracts, is overexpressed as an aberrant or deglycosylated form in various tumors such as gastric carcinomas and some hormone-refractory prostate cancers. MUC2 protein is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition. Vaccination with MUC2-KLH may result in the production of antibodies as well as elicit a cytotoxic T- lymphocyte (CTL) response against tumor cells expressing MUC2</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5169</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/547</obo:IAO_0000233>
        <obo:OGG_0000000006>4583</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5169</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC2</rdfs:comment>
        <rdfs:label>MUC-2-KLH vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007421 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007421">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007421</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5123</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/548</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5123</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>MUC1 antigen/SB AS-2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007422 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007422">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007422</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine, containing human tumor-associated epithelial mucin (MUC1) conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with MUC1-KLH conjugate vaccine may stimulate humoral and cytotoxic T-lymphocyte (CTL) responses against tumor cells expressing the MUC1 antigen. In this vaccine, MUC1 antigen is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition. MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in an aberrant or deglycosylated form in various cancers such as those of the breast, prostate, and ovary.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5251</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/549</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5251</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>MUC1-KLH conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007423 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007423">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007423</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine containing the human tumor-associated antigen epithelial mucin (MUC1 antigen) conjugated with keyhole limpet hemocyanin (KLH) and combined with the nonspecific immunoadjuvant QS21, with potential antineoplastic activity. MUC1 antigen is linked with KLH, an immunostimulant and a hapten carrier, in order to enhance immune recognition; the co-administration of saponin-derived QS21 potentially amplifies the total immune response to the MUC1 antigen. Administration of MUC1-KLH vaccine/QS21 may result in both the production of antitumor antibodies and the stimulation of a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the MUC1 antigen. MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed as an aberrant or deglycosylated form in various cancers such as breast, prostate and ovarian cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5160</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/550</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5160</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>MUC1-KLH vaccine/QS21</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007424 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007424">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007424</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5068</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/551</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5068</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>MUC1-targeted peptide GO-203-2C vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007425 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007425">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007425</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5522</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/552</obo:IAO_0000233>
        <obo:OGG_0000000006>2348</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5522</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FOLR1</rdfs:comment>
        <rdfs:label>multi-epitope folate receptor alpha peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007426 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007426">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007426</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of a combination of the injectable formulations S-488210, which contains the three HLA-A*02:01-restricted peptides up-regulated lung cancer 10 (lymphocyte antigen 6K; LY6K; URLC10), cell division cycle-associated protein 1 (kinetochore protein Nuf2; NUF2; CDCA1) and insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3; KOC1) and S-488211, which contains the two HLA-A*02:01-restricted peptides DEP domain-containing protein 1A (DEPDC1) and M-phase phosphoprotein 1 (kinesin-like protein KIF20B; MPHOSPH1), with potential immunostimulatory and antitumor activities. Upon administration, multipeptide vaccine S-588210 may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing KOC1, CDCA1, URLC10, DEPDC1 or MPHOSPH1 peptides, resulting in tumor cell lysis and decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5064</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/556</obo:IAO_0000233>
        <obo:OGG_0000000006>10643</obo:OGG_0000000006>
        <obo:OGG_0000000006>54742</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5064</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IGF2BP3</rdfs:comment>
        <rdfs:comment>Gene name: LY6K </rdfs:comment>
        <rdfs:label>multipeptide vaccine S-588210</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007427 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007427">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007427</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous dendritic cells which have been pulsed with a mutant p53 peptide. Vaccination with mutant p53 peptide pulsed dendritic cells may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing mutant p53, resulting in tumor cell lysis. Many tumor cells overexpress mutant p53 proteins, resulting in the loss of apoptosis regulation and abnormal cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5364</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/559</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5364</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mutant p53 peptide pulsed dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007428 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007428">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007428</metadata:prefixIRI>
        <obo:IAO_0000115>A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory activity against antigens. Vaccination with MVA-MUC1-IL2 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing MUC1, a tumor associated antigen, resulting in tumor cell lysis. Expression of IL-2 augments the specific CTL response against MUC1 expressing cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5091</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/564</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5091</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>MVA-MUC1-IL2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007429 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007429">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007429</metadata:prefixIRI>
        <obo:IAO_0000115>A combination peptide vaccine of 2 chimeric peptides of the promiscuous T cell epitope derived from measles virus fusion protein (MVF; amino acid residues 288-302) co-synthesized with B-cell epitopes derived from the HER-2/neu a.a. 597-626 and HER-2/neu a.a. 266-296, with potential antineoplastic activity. Vaccination with MVF-HER-2(597-626)/MVF-HER-2(266-296) peptide vaccine may be capable of inducing an active specific immune response, mounting a cytotoxic T-lymphocyte (CTL) response and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells that overexpress the HER-2 protein. The oncogenic protein HER-2, a member of the human epidermal growth factor receptor (EGFR) family of tyrosine kinases, is overexpressed in a variety of cancers and is correlated with increased tumor growth, progression and a poor prognosis. HER-2(597-626) corresponds to the binding site of trastuzumab on the extracellular domain IV of HER-2; HER-2 (266-296) corresponds to the binding site of pertuzumab on the dimerization loop of domain II of HER-2</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5400</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/566</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5400</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>MVF-HER-2(597-626)/MVF-HER-2 (266-296) peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007430 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007430">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004914"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005488"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007430</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine formulation consisting of several types of human papillomavirus (HPV)-derived noninfectious virus-like particles (VLPs) with potential immunoprophylactic activity. Upon administration, HPV L1 VLP vaccine V504 may generate humoral immunity against various HPV L. major capsid proteins, thereby preventing cervical infection upon exposure to the associated HPV types. VLPs are composed of self-assembling L. major capsid proteins or functional L. major capsid protein derivatives.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5449</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/450</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5449</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Human Papilloma Virus L1 Virus-Like Particle V504 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007431 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007431">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007431</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5408</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/478</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:OGG_0000000006>2829163</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4362"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5408</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:comment>Gene name: HPV6 E6</rdfs:comment>
        <rdfs:label>liposomal HPV-16 E6/E7 multipeptide vaccine PDS0101</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007432 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007432">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005426"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_3347"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007432</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a humanized monoclonal antibody that mimics a tumor-associated antigen 791Tgp72 (also known as CD55). Vaccination with this agent may stimulate a host cytotoxic T-cell response against tumor cells expressing CD55, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5195</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/532</obo:IAO_0000233>
        <obo:OGG_0000000006>1604</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3347"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5195</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD55</rdfs:comment>
        <rdfs:label>monoclonal antibody 105AD7 anti-idiotype vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007433 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007433">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005496"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007433</metadata:prefixIRI>
        <obo:IAO_0000115>A multipeptide vaccine consisting of peptides derived from lymphocyte antigen 6 complex locus K (LY6K) and type I and II vascular endothelial growth factor receptors (VEGFRs) with potential antineoplastic activity. Upon administration, LY6K/VEGFR1/VEGFR2 multipeptide vaccine may elicit an antitumor cytotoxic T-lymphocyte (CTL) immune response against LY6K-expressing tumor cells and/or VEGFR-expressing vascular endothelial cells involved in tumor angiogenesis. LY6K is a tumor-associated antigen (TAA) that occurs singly in glycosylphosphatidyl-inositol (GPI)-linked cell-surface glycoproteins or as three-fold repeated domain in the urokinase-type plasminogen activator receptor; VEGFRs are cell surface receptors that stimulate endothelial cell proliferation, invasion, angiogenesis, and vasculogenesis upon ligand binding and receptor activation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5164</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/486</obo:IAO_0000233>
        <obo:OGG_0000000006>54742</obo:OGG_0000000006>
        <obo:OGG_0000000006>7422</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5164</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: LY6K</rdfs:comment>
        <rdfs:comment>Gene name: VEGFA</rdfs:comment>
        <rdfs:label>LY6K/VEGFR1/VEGFR2 Multipeptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007434 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007434">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005426"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005490"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005496"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10534"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007434</metadata:prefixIRI>
        <obo:IAO_0000115>A carbohydrate-based vaccine comprised of the Globo H hexasaccharide 1 (Globo H) antigen conjugated to DT-CRM197, a non-toxic, mutated form of diphtheria toxin (DT), with potential immunostimulating and antineoplastic activities. Upon administration of Globo H-DT vaccine OBI-833, the carbohydrate antigen Globo H may stimulate a cytotoxic T-lymphocyte (CTL) response against Globo H-expressing tumor cells, thereby decreasing tumor cell proliferation. The hexasaccharide Globo H is a tumor-associated antigen (TAA) commonly found on a variety of tumor cells. DT-CRM197, also called diphtheria toxin cross-reacting material 197, is used to increase the immunogenicity of the Globo H carbohydrate antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5055</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/172</obo:IAO_0000233>
        <obo:OGG_0000000006>11716682</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10534"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5055</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: tox1</rdfs:comment>
        <rdfs:label>Globo H-DT vaccine OBI-833</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007435 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007435">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_3369"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007435</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide derived from the protein ESW/FLI1 type 2 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing&apos;s sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-2 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FL1 type 2 fusion protein. (NCIT_C49064).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:/2753158</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5432</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/63</obo:IAO_0000233>
        <obo:OGG_0000000006>297374825</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3369"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5432</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD22</rdfs:comment>
        <rdfs:label>EF-2 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007436 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007436">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_3068"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007436</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with six synthetic glioblastoma (GBM) peptides: absent in melanoma 2 (AIM-2), melanoma-associated antigen 1 (MAGE-1), tyrosinase-related protein 2 (TRP-2), glycoprotein 100 (gp100), epidermal growth factor receptor 2 (HER-2), interleukin-13 receptor subunit alpha-2 (IL-13Ra2), with potential immunostimulatory and antineoplastic activities. Mononuclear cells obtained via leukapheresis are differentiated into DCs, and pulsed with the GBM-associated peptides. Upon administration, multi-glioblastoma-peptide-targeting autologous DC vaccine ICT-107 exposes the immune system to GBM-associated antigens, which activates a specific cytotoxic T-lymphocyte (CTL) response against GBM cells. This leads to GBM cell lysis. The six peptides are derived from tumor associated antigens (TAA) expressed on GBM cells and cancer stem cells (CSCs). GBM stem-like cells contain a specific range of antigens that are essential for the neoplastic growth and survival of GBM cells</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5421</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/554</obo:IAO_0000233>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3068"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5421</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA1</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>multi-glioblastoma-peptide-targeting autologous dendritic cell vaccine ICT-107</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007437 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007437">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005503"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0081267"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007437</metadata:prefixIRI>
        <obo:IAO_0000115>A preparation of allogeneic HLA-matched leukocytes treated with a derivative of placental protein 14 (PP14) with potential immunomodulating activity. PP14 derivative-treated HLA-matched donor mononuclear cell-enriched leukocytes contain at least fifty-five percent early-apoptotic T cells; after infusion and when processed by recipient dendritic cells, early-apoptotic T cells may help induce a decrease in the donor effector T-cell responses against the recipient of an allogeneic hematopoietic stem cell (HSC) transplant, thereby minimizing allogeneic HSC transplant-related graft-versus-host disease (GVHD). PP14, a 162 amino acid glycosylated protein secreted by the late secretory phase endometrium, binds to T cells in a carbohydrate fashion and has been shown to induce T-cell apoptosis; maternal immune tolerance to the fetus and pregnancy-related remissions of autoimmune disease may involve PP14-induced T cell apoptosis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5093</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/427</obo:IAO_0000233>
        <obo:OGG_0000000006>5047</obo:OGG_0000000006>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0081267"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5093</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PAEP</rdfs:comment>
        <rdfs:label>HLA-Matched Donor Mononuclear Cell-Enriched Leukocytes Apocell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007438 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007438">
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            </owl:Restriction>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11934"/>
            </owl:Restriction>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007438</metadata:prefixIRI>
        <obo:IAO_0000115>Human mesenchymal stem cells (MSCs) transduced with a retroviral vector encoding a modified form of the cytokine interleukin-12 (IL-12), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration, IL-12-expressing MSC vaccine GX-051 secretes IL-12. IL-12 activates the immune system by both promoting the secretion of interferon-gamma, which activates natural killer cells (NKs), and inducing cytotoxic T-cell responses, which may result in both decreased cell proliferation and increased cell death in tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5168</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/461</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11934"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5168</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>IL-12-expressing Mesenchymal Stem Cell Vaccine GX-051</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007439 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007439</metadata:prefixIRI>
        <obo:IAO_0000115>A dendritic cell (DC)-based vaccine composed of program death ligands 1 and 2 (PDL1/L2)-silenced DCs and loaded with the recipient&apos;s minor histocompatibility antigens (MiHA), with potential use for graft-versus-tumor (GVT) induction following allogeneic stem cell transplantation (allo-SCT). Donor DCs are electroporated ex vivo with MiHA mRNA and small interfering RNAs (siRNAs) designed to silence the expression of PD L1/L2. After allo-SCT and upon intravenous administration of the MiHA-loaded PD-L1/L2-silenced DC vaccine, the DCs induce the expansion and activation of MiHA-specific CD8-positive T-cells. These tumor antigen-reactive T-cells exert their GVT effect by killing miHA-positive tumor cells. PD-L1/L2, co-inhibitory ligands expressed on DCs, play key roles in preventing MiHA-specific CD8-positive T-cell expansion; silencing enhances MiHA-specific CD8-positive T-cell expansion and activity and improves the GVT effect. The MiHA are human leukocyte antigen (HLA)-bound peptides and are exclusively expressed by the recipient&apos;s hematopoietic tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5015</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/528</obo:IAO_0000233>
        <obo:OGG_0000000006>5133</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2531"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5015</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PDCD1</rdfs:comment>
        <rdfs:label>MiHA-loaded PD-L1/L2-silenced dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007440 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007440">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007440</metadata:prefixIRI>
        <obo:IAO_0000115>A multi-antigen DNA vaccine consisting of plasmids encoding the hepatitis C virus (HCV) nonstructural proteins 3 (NS3), 4A (NS4A), 4B (NS4B) and 5A (NS5A), with potential immunomodulating and cancer preventive activities. Administered via intramuscular injection followed by electroporation, cells transfected with the HCV DNA vaccine INO-8000 express the encoded HCV proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against HCV-infected liver cells expressing the NS3, NS4A, NS4B or NS5A proteins. This results in the eradication of HCV-infected cells. HCV, a small, enveloped, single-stranded RNA virus belonging to the Flaviviridae family, is associated with the development of hepatocellular carcinoma (HCC)</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5002</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/304</obo:IAO_0000233>
        <obo:OGG_0000000006>3845</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5002</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KRAS</rdfs:comment>
        <rdfs:label>HCV DNA Vaccine INO-8000</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007441 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007441">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005499"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007441</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the suicide gene FCU1 with potential antineoplastic activity. FCU1 is a bifunctional yeast cytosine deaminase (CD) / uracil phosphoribosyltransferase (UPRT) fusion gene. Upon intratumoral administration, MVA-FCU1TG4023 enters tumor cells where FCU1 is expressed. Subsequently, the noncytotoxic prodrug 5-fluorocytosine (5-FC) is administered systemically and is deaminated by CD in FCU1- transduced tumor cells into 5-fluorouracil (5-FU), which is then directly metabolized to 5-fluoro-uridine monophosphate (5-FUMP) by UPRT; 5-FUMP may then be further transformed to 5-fluoro-deoxyuridine monophosphate (5-FdUMP), an irreversible inhibitor of thymidylate synthase and, so, DNA synthesis through deprivation of deoxythymidine triphosphate (dTTP). 5-FU and its active metabolites may then selectively kill tumor cells, avoiding toxicity in nonmalignant cells. The MVA viral vector, derived from the replication-competent strain Ankara, is a highly attenuated, replication-defective vaccinia strain incapable of virion assembly</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5312</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/563</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5312</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>MVA-FCU1 TG4023 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007442 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007442">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000295"/>
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        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007442</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic HIV vaccine based on a recombinant canary pox virus vector expressing the human immunodeficiency virus (HIV) glycoprotein gp160. HIVgP160 vaccine has been used to generate in vivo primary T lymphocyte response against HIV antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/308</obo:IAO_0000233>
        <obo:OGG_0000000006>155971</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_635"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12721"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: env</rdfs:comment>
        <rdfs:label>HIVgP160 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007443 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007443">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007656"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007443</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide derived from the oncogenic human papillomavirus (HPV) early gene product E6. The HPV 16 transforming protein E6 is expressed in precancerous and malignant cervical lesions and has a high affinity for the most common human lymphocyte antigen (HLA), HLA-A2. Immunogenic peptides from the HPV 16 E6 may be used to trigger a T-cell-mediated immune response to HPV.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>HPV 16 E6 (18-26) peptide vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5474</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/429</obo:IAO_0000233>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5474</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:label>human papillomavirus  16 E6 (18-26) peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007444 -->

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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007444</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide vaccine consisting of amino acids 86 through 93 (TLGIVCPI) of the viral oncoprotein human papillomavirus (HPV) 16 E7. Vaccination with HPV-16 E7:86-93 peptide, which binds to HLA-A* 0201 molecule, may stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV-16 E7.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>HPV 16 E7:86-93 peptide vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5184</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/431</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5184</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>human papillomavirus  16 E7:86-93 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007445 -->

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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007445</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of human papillomavirus-derived noninfectious virus-like particles (VLPs), containing the L. major capsid protein. Vaccination with HPV 16 L1-VLP results in increases in T cell-proliferative response to HPV 16 L1-VLP, as well as significant increases in cytokine (interferon-gamma, interleukin-5 and -10) responses to L1 VLP. This agent may reduce the incidence of persistent HPV-16 infection, which may be responsible for half of all cases of cervical cancer including high-grade cervical intraepithelial neoplasia.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>HPV 16 L1-VLP vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5520</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/432</obo:IAO_0000233>
        <obo:OGG_0000000006>25479185</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5520</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: L1</rdfs:comment>
        <rdfs:label>human papillomavirus  16 L1-VLP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007446 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007446">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007446</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide vaccine consisting of amino acids 13 through 21 of the viral oncoprotein human papillomavirus (HPV) 18 E6. The HPV 18E6 peptide cross-reacts immunologically with both HPV type 16 and HPV type 18, the most common HPV types involved in cervical cancer. Vaccination with HPV-18 E6:13-21 peptide may stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV 16 and 18.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>HPV 18 E6:13-21 peptide vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5159</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/433</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5159</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>human papillomavirus  18 E6:13-21 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007447 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007447">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007447</metadata:prefixIRI>
        <obo:IAO_0000115>Noninfectious, synthetic, virus-like particles (VLP) containing the major viral capsid protein, L1, of the human papillomavirus type 18 with potential immunoprotective activity. Vaccination with HPV 18 L1-VLP may stimulate the host immune system to mount cytotoxic T lymphocyte (CTL) response against cells positive for HPV 18, thereby preventing cervical infection upon exposure to HPV type 18.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>HPV 18 L1-VLP vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5247</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/434</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5247</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>human papillomavirus  18 L1-VLP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007448 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007448">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007448</metadata:prefixIRI>
        <obo:IAO_0000115>A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus (HPV) subtypes 16 and 18, respectively, with potential immunostimulating and antineoplastic activities. Administered via intramuscular electroporation, HPV DNA plasmids therapeutic vaccine VGX-3100 expresses E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against cervical cancer cells expressing E6 and E7 proteins, resulting in tumor cell lysis. HPV type 16 and HPV type 18 are the most common HPV types involved in cervical carcinogenesis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>HPV DNA plasmids therapeutic vaccine VGX-3100</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5226</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/435</obo:IAO_0000233>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5226</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>human papillomavirus  DNA plasmids therapeutic vaccine VGX-3100</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007449 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007449</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine directed against Human Papillomavirus Type 11 that causes majority of the genital warts and anogenital cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>HPV-11 Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5227</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/437</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5227</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>human papillomavirus -11 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007450 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007450">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007656"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007450</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic agent derived from human papillomavirus (HPV) E7 nuclear protein which is used to produce vaccines against HPV infection and HPV-related neoplasms. HPV E7 oncogenic protein binds the retinoblastoma tumor suppressor protein, pRB, as well as a number of other cellular proteins, and serves as a transcriptional activator. This protein is important in the induction and maintenance of cellular transformation and is co-expressed in the majority of HPV-containing carcinomas. PADRE(R) is a proprietary family of molecules that enhances the immune systems response against an administered immunogen such as the HPV E7 nuclear protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5162</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/451</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5162</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>human papillomavirus 16 E7 peptide/padre 965.10 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007451 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007451">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004914"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007656"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007451</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant, bivalent, human papillomavirus (HPV) vaccine, containing virus-like particles for HPV types 16 and 18 linked to the adjuvant ASO4, with potential immunoprotective and antineoplastic properties. Upon administration, HPV 16/18 L1 virus-like particle/ASO4 vaccine may generate humoral and cellular immunity against HPV types-16 and -18 antigens, thereby preventing cervical infection upon exposure to HPV types 16 and 18. In addition, this agent may stimulate an antitumoral cellular immune response against cervical cancer associated with HPV infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5233</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/452</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5233</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>human papillomavirus 16/18 L1 virus-like particle/AS04 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007452 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007452">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007656"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007452</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccinia viral based vaccine, encoding epitopes of E6 and E7 proteins from human papillomavirus (HPV) types 16 and 18, with immunostimulatory and antineoplastic activities. HPV types 16 and 18 account for approximately 70% of cervical cancers. Vaccination with this HPV-TA (tumor antigen) vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for E6 and E7 from either type 16 or 18 HPV, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5279</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/453</obo:IAO_0000233>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5279</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>human papillomavirus tumor antigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007453 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007453">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007656"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007453</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of noninfectious, recombinant virus-like particles (VLP) containing the major viral capsid protein L1 of nine strains of human papillomavirus (HPV), with potential immunoprotective activity. Vaccination with HPV V503 may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against cells positive for any of these nine strains of HPV, thereby preventing cervical infection upon exposure to certain HPV subtypes.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5167</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/454</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5167</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: major capsid protein L1</rdfs:comment>
        <rdfs:label>human papillomavirus vaccine V503</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007454 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007454">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007656"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007454</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide based vaccine consisting of amino acids 12 through 20 of the E7 gene of the Human Papilloma Virus type 16. HPV-16 E7 12-20 peptide vaccine may elicit a specific CD8 T-cell response to the E7 oncogene protein, thereby inhibiting the abrogation of p53 and pRb function and thus prevent tumorigenesis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5079</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/430</obo:IAO_0000233>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5079</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>human papillomavirus  16 E7:12-20 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007455 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007455</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic DNA vaccine encoding the E6/E7 fusion protein of human papillomavirus (HPV) subtypes 16 and 18, plus the immune-enhancer, Fms-like tyrosine kinase-3 ligand (FLT3L), with potential immunostimulating and antineoplastic activities. DNA vaccine GX-188E is administered using a proprietary delivery system that electroporates the vaccine into cervical cells. Expression of the E6/E7 fusion product may elicit a cytotoxic T-lymphocyte (CTL) response against cervical cancer cells expressing E6 and E7 oncoproteins, resulting in tumor cell lysis. FLT3L is a ligand for the FLT3 tyrosine kinase receptor, which upon activation stimulates the proliferation of hematopoietic progenitor cells. HPV type 16 and 18 are the most common HPV types involved in cervical carcinogenesis</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5083</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/436</obo:IAO_0000233>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/VO_0007653"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5083</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>human papillomavirus  E6/E7 DNA vaccine GX-188E</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007456 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007456</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of a plasmid DNA encoding the human prostate-specific membrane antigen (PSMA). Upon administration, expressed PSMA may stimulate a cytotoxic T cell response against tumor cells that express this antigen, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5262</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/455</obo:IAO_0000233>
        <obo:OGG_0000000006>2346</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
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        <obo:VO_0001818>5262</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Prostate-specific membrane antigen</rdfs:comment>
        <rdfs:label>Human Prostate-Specific Membrane Antigen Plasmid DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007457 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007457</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of a plasmid DNA encoding the murine prostate-specific membrane antigen (PSMA). Upon administration, expressed PSMA may stimulate a cytotoxic T cell response against tumor cells that express PSMA, resulting in tumor cell lysis</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5105</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/540</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5105</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Mouse Prostate-Specific Membrane Antigen Plasmid DNA Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007458 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007458">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005487"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007458</metadata:prefixIRI>
        <obo:IAO_0000115>Early-to late-stage myeloid progenitor cells derived from adult human stem cells with potential hematopoietic activity. Upon infusion, human myeloid progenitor cells CLT-008 proliferate into mature myeloid cells, including granulocytes, macrophages, platelets, and erythrocytes. These myeloid progenitor cells die within forty-five days after a burst of hematopoiesis. This agent cannot create lymphoid cells, including T cells associated with graft-versus-host disease</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5511</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/449</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5511</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Human Myeloid Progenitor Cells CLT-008 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007459 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007459">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005487"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007459</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with corpses of apoptotic leukemic cells, with potential immunostimulatory and antineoplastic activities. Upon vaccination, autologous dendritic cells pulsed with leukemic apoptotic corpse may activate the immune system to mount an anti-tumoral cytotoxic T-lymphocyte (CTL) response against leukemic cells expressing leukemia-associated antigens, which may result in leukemic cell lysis and inhibition of tumor cell growth. Apoptotic tumor cell corpses contain an array of tumor associated antigens</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5004</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/476</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5004</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Leukemic Apoptotic Corpse-Pulsed Autologous Dendritic Cells Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007460 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007460">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007460</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5200</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/555</obo:IAO_0000233>
        <obo:OGG_0000000006>3077513</obo:OGG_0000000006>
        <obo:OGG_0000000006>3077579</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
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        <obo:VO_0001818>5200</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: UL123</rdfs:comment>
        <rdfs:comment>Gene name: UL83</rdfs:comment>
        <rdfs:label>multi-peptide CMV-modified vaccinia ankara vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007461 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007461</metadata:prefixIRI>
        <obo:IAO_0000115>This is an autologous lung cancer vaccine consisting of patient-specific lung cancer cells genetically modified to secrete granulocyte-macrophage colony stimulating factor (GM-CSF), an immunostimulatory cytokine (NCIT_C1979). GM-CSF modulates the proliferation and differentiation of a variety of hematopoietic progenitor cells with some specificity towards stimulation of leukocyte production and may reverse treatment-induced neutropenias.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5453</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/302</obo:IAO_0000233>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5453</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:label>GVAX Lung Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007462 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007462</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is a bivalent vaccine with the antigens GD2L and GD3L for patients with High-Risk Neuroblastoma. The antigens are linked to KLH and mixed with OPT-821. It is given in combination with oral β-glucan, which can help white blood cells kill cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00911560</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6262</obo:IAO_0000119>
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        <obo:VO_0001818>6262</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>bivalent neuroblastoma vaccine with adjuvant OPT-821</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007463 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007463</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. gp100:280-288(288V) peptide has a valine substitution at amino acid position 288 to improve immunogenicity. Vaccination with gp100:280-288(288V) peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5112</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/419</obo:IAO_0000233>
        <obo:OGG_0000000006>3791</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5112</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KDR</rdfs:comment>
        <rdfs:label>HLA-A*2402-Restricted VEGFR1 peptide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007464 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007464</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing two HLA-A*0201-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this vaccine are derived from: vascular endothelial growth factor receptors (VEGFR) 1 and 2. Upon administration, HLA-A*0201-restricted VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing VEGFR 1 and 2 peptides, resulting in tumor cell lysis and decreased tumor growth. HLA-A*0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5294</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/420</obo:IAO_0000233>
        <obo:OGG_0000000006>3791</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5294</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KDR</rdfs:comment>
        <rdfs:label>HLA-A2402-restricted VEGFR1/2 multipeptide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007465 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007465</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of allogeneic neuroblastoma tumor cells have been genetically modified to secrete the human cytokine interleukin-2 (IL-2) and the human chemokine lymphotactin (Lptn) with potential immunostimulating and antineoplastic activities. Upon administration, IL-2 and Lptn are secreted by the IL-2/Lptn gene-modified allogeneic neuroblastoma tumor cell vaccine, potentially enhancing the cytotoxic T lymphocyte (CTL) response elicited by vaccine neuroblastoma tumor-associated antigens (TAAs) against host neuroblastoma tumor cells. Produced by activated progenitor T cells, Lptn belongs to the C chemokine subfamily and is a potent chemotactic factor for lymphocytes; IL-2 stimulates natural killer (NK) cells and may enhance a vaccine-elicited CTL immune response against tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5173</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/462</obo:IAO_0000233>
        <obo:OGG_0000000006>6375</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5173</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: XCL1</rdfs:comment>
        <rdfs:label>IL-2/Lptn gene-modified allogeneic neuroblastoma tumor cell vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007466 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007466</metadata:prefixIRI>
        <obo:IAO_0000115>An immunotherapeutic containing a proprietary adjuvant system combined with a melanoma-associated antigen peptide MAGE-A3 epitope with potential immunomodulating and antineoplastic activities. Intramuscular administration with GSK1572932A may stimulate the immune system to exert both humoral and cellular immune responses against MAGE-A3-expressing tumor cells. MAGE-A3, a tumor associated antigen (TAA), is overexpressed in a variety of tumor cell types, including non-small cell lung cancer (NSCLC), melanoma, head and neck cancer, and bladder cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>Immunotherapeutic GSK1572932A</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5343</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/463</obo:IAO_0000233>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5343</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:label>immunotherapeutic GSK1572932A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007467 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005486"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007467</metadata:prefixIRI>
        <obo:IAO_0000115>GVAX cancer vaccines are autologous cell vaccines comprised of tumor cells which have been irradiated and genetically modified to secrete granulocyte-macrophage colony stimulating factor (GM-CSF), a hormone which plays a key role in stimulating the body&apos;s immune response to vaccines.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5211</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/301</obo:IAO_0000233>
        <obo:OGG_0000000006>1493</obo:OGG_0000000006>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5211</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTLA4</rdfs:comment>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>GVAX cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007468 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007468">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007468</metadata:prefixIRI>
        <obo:IAO_0000115>A replication-defective adenoviral serotype 5 vector encoding a recombinant form of the human cytokine interferon-gamma (IFN-g), with potential antineoplastic and immunoregulatory activities. Upon intratumoral administration, the sustained expression of IFN-g by IFN-g-expressing adenovirus vaccine ASN-002 promotes a T-helper type 1 (Th1) immune response and inhibits the Th2-mediated cytokine production observed in many cutaneous lymphomas. IFN-g also mediates interleukin-12 (IL-12) production by antigen-presenting cells (APCs); activates macrophages, cytotoxic T-cells, and natural killer (NK) cells; upregulates major histocompatibility complex (MHC) molecules; and stimulates antibody-dependent cellular cytotoxicity (ADCC). Altogether, these IFN-g-mediated effects may result in both an inhibition of tumor cell proliferation and tumor cell death. Compared to IFN-g injections, the prolonged local production of IFN-g at the tumor site allows for higher efficacy and a reduction of systemic toxicity</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5540</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/470</obo:IAO_0000233>
        <obo:OGG_0000000006>2546420</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5540</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: WHcAg</rdfs:comment>
        <rdfs:label>Interferon-gamma-expressing Adenovirus Vaccine ASN-002</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007469 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007469">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007469</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine based on anti-idiotype (Id) monoclonal antibodies combined with interleukin-2 (IL-2). Anti-Id vaccines have been shown to be effective in treatment of B-cell lymphoma in animal models and in clinical trials, resulting in tumor regression; the addition of interleukin-2 (IL-2) may augment the therapeutic effect of anti-Id vaccines.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5352</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/471</obo:IAO_0000233>
        <obo:OGG_0000000006>5176180</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5352</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp72</rdfs:comment>
        <rdfs:label>Interleukin-2 Anti-Idiotype Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007470 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007470">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007470</metadata:prefixIRI>
        <obo:IAO_0000115>A chimeric lymphoma vaccine generated by combining the recipient&apos;s Ig idiotype (Id) protein with keyhole limpet hemocyanin (KLH), an immune stimulant, with potential antineoplastic activity. Vaccination with KLH-Lymphoma Ig Vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against lymphoma cells, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5519</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/474</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5519</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>KLH-Lymphoma Ig Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007471 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007471">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007471</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/487"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0004398"/>
        <rdfs:comment>Gene name: Fragment C from tetanus toxin</rdfs:comment>
        <rdfs:label>obsolete Lymphoma DNA vaccine V_V_V_-FrC</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007472 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007472">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007472</metadata:prefixIRI>
        <obo:IAO_0000115>A preparation of autologous peripheral blood mononuclear cells (PBMCs) radiolabeled with indium In 111 with radioisotopic activity. Autologous PBMCs are isolated, expanded ex vivo, radiolabeled with indium In 111, and then infused back into the patient. Gamma scintigraphy may then be used to image gamma ray-emitting indium In 111 PBMCs localized in lymphoma tissue.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5212</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/467</obo:IAO_0000233>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10154"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5212</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:label>indium in 111-labeled autologous peripheral blood mononuclear cells vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007473 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007473">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007473</metadata:prefixIRI>
        <obo:IAO_0000115>A preparation of autologous peripheral polymorphonuclear (PMNLs) radiolabeled with indium In 111 with radioisotopic activity. Autologous PMNLs are isolated, expanded ex vivo, radiolabeled with indium In 111, and then infused back into the patient. Gamma scintigraphy may then be used to image gamma ray-emitting indium In 111 PMNLs localized in lymphoma tissue.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5273</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/468</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10154"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5273</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>indium in 111-labeled autologous polymorphonuclear leukocytes vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007474 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007474">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007474</metadata:prefixIRI>
        <obo:IAO_0000115>Human peripheral blood lymphocytes (PBL) isolated from a patient, exposed to the tumor-associated protein ESO-1 in vitro, and then transferred back to the same patient to target tumor cells expressing ESO-1. ESO-1 is a human self-antigen expressed by melanomas. The ESO-1 gene encodes several MHC class I- and MHC class II-restricted epitopes that may activate cytotoxic T-cell-mediated tumor destruction</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5178</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/?term=ESO-1+Reactive+Autologous+Peripheral+Blood+Lymphocyte</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/67</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5178</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>ESO-1 reactive autologous peripheral blood lymphocyte vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007475 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007475">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007475</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant fowlpox virus-based vaccine vector designed to express various tumor-associated peptide antigens. Strong CD8 cytotoxic T cell responses may be induced after prolonged immunization with fowlpox virus vaccines and have been associated with tumor regression. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5042</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/130</obo:IAO_0000233>
        <obo:OGG_0000000006>	4582</obo:OGG_0000000006>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5042</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM5</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>fowlpox virus vector vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007476 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007476">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007476</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing of a synthetic form of the renal cell carcinoma (RCC)-associated antigen G250 with potential antineoplastic activity. Vaccination with G250 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the G250 antigen, resulting in decreased tumor growth. Found in the majority of renal cell carcinomas, G250 is a cell surface tumor-associated antigen (TAA) that contains an HLA-A2.1-restricted epitope that is recognized by CTLs.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5249</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/135</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5249</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:label>Gag:267-274 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007477 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007477">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007477</metadata:prefixIRI>
        <obo:IAO_0000115>An autologous dendritic cell (DC) cancer vaccine with GITRL RNA-transfected that has potential immunostimulatory activity. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5410</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/136</obo:IAO_0000233>
        <obo:OGG_0000000006>1493</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5410</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTLA4</rdfs:comment>
        <rdfs:label>GITRL RNA-transfected autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007478 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007478">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007478</metadata:prefixIRI>
        <obo:IAO_0000115>Used C57BL/6 mice and irradiated B16 tumor cells expressing granulocyte and macrophage colony-stimulating factor (GM-CSF), interleukin-12 (IL-12) or both. Tumor was transplanted by the injection of wild-type B16 cells. Tumor growth and survival were measured to evaluate the efficacy of vaccination. Specific humoral response and immunoglobulin G (IgG) switch were evaluated measuring total IgG and IgG1 and IgG2a subtypes against tumor membrane proteins of B16 cells</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4061</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/176</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4061</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>GM-CSF, IL-12 and GM-CSF+IL-12 genetically modified tumor cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007479 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007479">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007479</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant, oncolytic serotype 5/3 capsid-modified adenovirus encoding the immunostimulatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) with potential antineoplastic activity. Upon administration, the oncolytic adenovirus selectively infects and replicates in tumor cells, which may result in tumor cell lysis. Synergistically, GM-CSF (sargramostim) expressed by the oncolytic adenovirus enhances antigen presentation, promotes natural killer (NK) cell-mediated killing and causes a cytotoxic T cell (CTL) response against tumor cells harboring the oncolytic adenovirus, resulting in an immune-mediated tumor cell death. CGTG-102 is designed to replicate only in cells with defects in the p16/Rb/E2F pathway, attributed to a mutation common in many solid tumors. Replacement of the Ad5 capsid protein knob with a knob domain from serotype 3 causes higher transduction in cancer cells as compared to normal cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5111</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/177</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5111</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>GM-CSF-encoding Oncolytic Adenovirus CGTG-102 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007480 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007480">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007658"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
            </owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007480</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made of peripheral blood and tumor specimen harvested from patients with metastatic adenocarcinoma of the pancreas to generate cancer stem cell (CSC)-loaded denritic cell (DC) vaccines. CSC-primed antibodies and T cells are capable of selective targeting CSCs and conferring antitumor immunity.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02074046</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6276</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6276</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>cancer stem cell-loaded dc vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007481 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007481</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that injected peptides of gp100, MART-1, MAGE-3</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3993</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/196</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3993</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100 + Mart-1 + Mart-3 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007482 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007482">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007482</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of a replication-defective recombinant adenovirus that encodes the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. Vaccination with gp100 adenovirus vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5133</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/197</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5133</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100 Adenovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007483 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007483">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007483</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of microscopic gold particles coated with plasmid DNA encoding the glycoprotein 100 (gp100) melanoma antigen and granulocyte-macrophage colony-stimulating factor (GM-CSF). Vaccination with gp100 and GM-CSF DNA/gold vaccine may stimulate the host immune system to direct cytotoxic T lymphocytes (CTL) against gp100 positive cells, resulting in decreased tumor growth. GM-CSF is thought to increase the induction and activation of antigen-presenting cells (APC), allowing for a reduction in the dose of gp100 administered.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5084</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/198</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5084</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100 and GM-CSF DNA/Gold vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007484 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007484">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007484</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant peptide derived from the human melanoma antigen glycoprotein 100 (gp100) with potential use in cancer immunotherapy. gp100 protein(184V) has a valine substitution at position 184. Vaccination with this peptide may evoke a cytotoxic T lymphocyte (CTL) response against tumor cells expression the gp100 antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5482</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/199</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5482</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100 Protein (184V) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007485 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007485">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007485</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant vaccinia virus encoding the gp100 melanoma-melanocyte antigen. gp100 human antigen is a wild-type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5153</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/200</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5153</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100 Vaccinia vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007486 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007486">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007486</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the melanoma antigen glycoprotein 100 (gp 100) with potential antineoplastic activity. The expression of gp100 may generate a cellular immune response to melanoma cells; this effect is enhanced by the co-administration of interleukin 2</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5135</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/201</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5135</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100-Fowlpox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007487 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007487">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007487</metadata:prefixIRI>
        <obo:IAO_0000115>Peripheral blood lymphocytes (PBL) harvested from host blood and stimulated in vitro with tumor-specific gp 100 antigen. &apos;Pulsing&apos; PBL with gp100, a tumor associated antigen (TAA) commonly expressed by melanoma cells, may increase melanoma-reactive cytotoxic lymphocytes (CTL) in the PBL cell population. Autologous gp100-pulsed PBL have been administered to melanoma patients in order to augment cytotoxic immune responses to melanoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5007</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/202</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5007</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100-Pulsed Peripheral Blood Mononuclear Cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007488 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007488">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007488</metadata:prefixIRI>
        <obo:IAO_0000115>Human peripheral blood lymphocytes (PBL) isolated from a patient, exposed to the tumor-associated antigen gp100 in vitro, and then transferred back to the same patient to target tumor sites expressing gp100. gp100 human antigen is a wild-type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4990</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/203</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4990</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100-Reactive Autologous Peripheral Blood Lymphocyte vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007489 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007489">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007489</metadata:prefixIRI>
        <obo:IAO_0000115>To understand why cancer vaccine-induced T cells often do not eradicate tumors, we studied immune responses in mice vaccinated with gp100 melanoma peptide in incomplete Freund&apos;s adjuvant (peptide/IFA), which is commonly used in clinical cancer vaccine trials (Hailemichael et al., 2013).
Immunization Route: Intramuscular injection (i.m.)</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4078</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/204</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4078</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100/IFA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007490 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007490">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007490</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide vaccine consisting of amino acids 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen with an endoplasmic reticulum signal sequence (ES) to increase binding activity. Vaccination with gp100:ES209-217(210M) may stimulate the host immune system to mount a cytotoxic T lymphocyte response against tumor cells positive for gp100, resulting in decreased tumor growth</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5095</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/205</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5095</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100: ES209-217(210M) Peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007491 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007491">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007491</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide consisting of amino acid residues 154 through 162 of the melanoma-melanocyte antigen gp100. Vaccination with gp100:154-162 peptide may enhance tumor-specific T-cell immunity. gp100 antigen is a self-antigen expressed by melanocytes, pigmented retinal cells, and most melanoma lesions and is recognized via class I and II HLA-restricted mechanisms.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5145</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/206</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5145</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100:154-162 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007492 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007492">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007492</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide vaccine consisting of amino acids 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen with an endoplasmic reticulum signal sequence (ES) to increase binding activity. Vaccination with gp100:ES209-217(210M) may stimulate the host immune system to mount a cytotoxic T lymphocyte response against tumor cells positive for gp100, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5050</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/207</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5050</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100:209-217 Peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007493 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007493">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007493</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. Vaccination with gp100:280-288 peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5526</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/208</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5526</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100:280-288 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007494 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007494</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3989</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/307</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3989</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>Hexapeptide melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007495 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007495">
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007495</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A1-binding melanoma-associated antigen peptides MAGE-1 and MAGE-3 with potential immunomodulating and antineoplastic activity. Upon vaccination, HLA-A1-binding MAGE-1/MAGE-3 multipeptide-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount an anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against MAGE1- and MAGE-3-expressing cancer cells, resulting in tumor cell lysis. HLA-A1 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A1 may improve antigenic peptide immunogenicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5185</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/423</obo:IAO_0000233>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5185</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA1</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:label>HLA-A1-binding MAGE-1/MAGE-3 multipeptide-pulsed autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007496 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007496">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007496</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted melanoma-associated antigen peptides tyrosinase (TYR), MART-1(melanoma antigen recognized by T-cells) and melanoma antigen glycoprotein 100 (gp100), with potential immunomodulating and antineoplastic activity. Upon vaccination, HLA-A2-binding TYR/MART-1/gp100 multipeptide-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount an anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against Tyr-, MART-1 and gp100-expressing cancer cells, resulting in tumor cell lysis. HLA-A2 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A2 may improve antigenic peptide immunogenicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5034</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/425</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5034</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: gp100 </rdfs:comment>
        <rdfs:label>HLA-A2-binding TYR/MART-1/gp100 multipeptide-pulsed autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007497 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007497">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007497</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing dendritic cells (DCs) that are transfected with messenger RNA (mRNA) encoding human telomerase reverse transcriptase (hTERT) and survivin in addition to patient-specific melanoma-derived mRNA with potential immunostimulatory and antineoplastic activities. Upon administration, hTERT/survivin/melanoma tumor cell-derived mRNA-transfected dendritic cell vaccine may elicit a highly specific cytotoxic T-cell (CTL) response against melanoma cells expressing hTERT, survivin, and patient-specific melanoma-associated antigens. hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types, playing key roles in tumor cell growth and survival. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5270</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/448</obo:IAO_0000233>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5270</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>hTERT/survivin/melanoma tumor cell-derived mRNA-transfected dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007498 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007498">
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007498</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine consisting of a combination of seven synthetic long peptides (SLPs), which are each about 30 amino acids in size, and derived from cancer-testis antigens (CTA) and melanocytic differentiation proteins (MDP), with potential immunostimulating and antitumor activities. Upon administration, long peptide vaccine 7 may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL) response against tumor cells expressing these peptides. CTA and MDP are overexpressed in a variety of cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5143</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/484</obo:IAO_0000233>
        <obo:OGG_0000000006>3845</obo:OGG_0000000006>
        <obo:OGG_0000000006>7157</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5143</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KRAS</rdfs:comment>
        <rdfs:comment>Gene name: TP53</rdfs:comment>
        <rdfs:label>long peptide vaccine 7</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007499 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007499">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007499</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide cancer vaccine consisting of human leukocyte antigen HLA-A1-restricted peptide derived from human melanoma antigen 3 (MAGE-3) with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-3.A1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-3, resulting in tumor cell lysis. MAGE-3, a tumor-associated antigen (TAA), is overexpressed by a variety of cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5021</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/489</obo:IAO_0000233>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5021</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:label>MAGE-3.A1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007500 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007500">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007500</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with chimeric antigen receptor (CAR) T cells that can be used to treat solid tumors. These CAR-T cells are engineered to target carbonic anhydrase IX (CAIX) to secrete anti-PD-L1 monoclonal antibody (mAb), termed immune-restoring (IR) CAR G36-PDL1. The T cells can be used to treat clear cell renal cell carcinoma (ccRCC) with reconstituted human leukocyte antigen (HLA) partially matched human leukocytes derived from fetal CD34+ hematopoietic stem cells (HSCs) and bearing human ccRCC skrc-59 cells under the kidney capsule. The cells can restore active antitumor immunity by promoting tumor-killing cytotoxicity, reducing immunosuppressive cell components such as M2 macrophages and exhausted CD8+ T cells, and enhancing T follicular helper (Tfh)-B cell crosstalk.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:38327771</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6380</obo:IAO_0000119>
        <obo:OGG_0000000006>3105</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6380</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HLA</rdfs:comment>
        <rdfs:label>CAR G36-PDL1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007501 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007501">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007501</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4003</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/497</obo:IAO_0000233>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4003</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>MART-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007502 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007502">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007502</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of recombinant adenovirus vector encoding MART-1 (melanoma antigen recognized by T-cells 1), an immunogenic protein of unknown function that is expressed by certain types of melanoma. Vaccination with MART-1 adenovirus vaccine may stimulate the host immune system to direct cytotoxic T lymphocytes (CTL) against MART-1 positive melanoma cells, resulting in an antitumor effect.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5398</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/498</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5398</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA-Dupli</rdfs:comment>
        <rdfs:label>MART-1 Adenovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007503 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007503">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007503</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic cancer vaccine derived from a melanoma-associated antigen, MART-1. Antigenic peptides derived from MART-1 are recognized by CD8+ T lymphocytes and have been used to immunize patients with advanced melanomas; prolonged immunization may result in a reduction in tumor size. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5254</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/502</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5254</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA-Dupli</rdfs:comment>
        <rdfs:label>MART-1 Fowlpox vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007504 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007504">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007504</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of an attenuated recombinant vaccinia virus expressing the melanoma-associated antigen MART-1. Vaccination with this agent may stimulate cytotoxic host immune responses to melanoma cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5204</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/503</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5204</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA-Dupli</rdfs:comment>
        <rdfs:label>MART-1 Vaccinia vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007505 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007505">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007505</metadata:prefixIRI>
        <obo:IAO_0000115>Irradiated allogeneic, HLA-A*0201 positive, plasmacytoid dendritic cells (pDCs) loaded with 4 melanoma peptides derived from the tumor associated antigens (TAAs) MelA/MART-1, gp100/pmel17, tyrosinase, and MAGE-A3, with potential immunostimulating and antineoplastic activities. Upon subcutaneous administration, the irradiated allogeneic pDCs may trigger functional multi-specific T cells from peripheral blood mononuclear cells and tumor-infiltrating lymphocytes, and activate the immune system to mount a cytotoxic T-lymphocyte response against HLA-A*0201 positive melanoma cancer cells expressing the TAAs MelA/MART-1, gp100/pmel17, tyrosinase, and MAGE-A3. These TAAs are upregulated in a variety of tumor cells. The pDCs are derived from a distinct subset of dendritic cells (DCs) with a plasma cell-like morphology and express a characteristic set of surface markers and may increase the anti-tumor immune responses.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5028</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/504</obo:IAO_0000233>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5028</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>MART-1/gp100/Tyrosinase/MAGE-A3 peptides-loaded irradiated allogeneic plasmacytoid dendritic cells vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007506 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007506">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007506</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5141</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/505</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5141</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>MART-1:26-35(27L) peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007507 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007507">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007507</metadata:prefixIRI>
        <obo:IAO_0000115>A natural or synthetic peptide cancer vaccine consisting of amino acid residues 27 through 35 of the melanoma-associated antigen MART-1 with potential antineoplastic activity. Vaccination with MART-1:27-35 peptide may induce cytotoxic host immune responses against melanoma cells that express this peptide</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5450</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/506</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5450</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:label>MART-1:27-35 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007508 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007508</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of the melanocyte differentiation antigen Melan A (also called MART-1) encapsulated in noninfectious virus-like particles (VLP) with potential immunostimulating and antineoplastic activities. Upon administration, Melan-A VLP vaccine may activate the immune system to exert a specific cytotoxic T lymphocyte (CTL) response against cancer cells expressing the Melan A antigen, resulting in tumor cell lysis. Melan A is an antigen that is upregulated in most melanomas. VLP stimulates the immune system and promotes the CTL response.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5142</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/507</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5142</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:label>Melan-A VLP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007509 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007509">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007509</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5318</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/508</obo:IAO_0000233>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5318</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:comment>Gene name: MLANA</rdfs:comment>
        <rdfs:label>Melan-A/MAGE-3.DP4 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007510 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007510">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005485"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007510</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine for bladder cancer designed to generate an immune response against a protein called human chorionic gonadotropin-beta (hCG-β). hCG-β is made by several types of cancers, including bladder cancer, and has been shown to be associated with shorter times to development of metastases and reduced survival in bladder cancer. Administering the CDX-1307 vaccine will cause the body&apos;s immune system to attack bladder cancer cells in order to kill them or otherwise keep them from spreading or coming back. The human monoclonal antibody (B11) directed against the mannose receptor and linked to the beta-subunit of human chorionic gonadotropin (hCG beta) with potential immunostimulating and antineoplastic activities. The monoclonal antibody moiety of human monoclonal antibody B11-hCG beta fusion protein CDX-1307 binds to mannose receptors on antigen presenting cells (APCs), including human dendritic cells (DCs) and macrophages. APCs present the processed hCG beta antigen on their cell surfaces, which may initiate an antibody-dependent cell-mediated cytotoxicity (ADCC) response against hCG beta-expressing tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C77858</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01094496</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6277</obo:IAO_0000119>
        <obo:OGG_0000000006>1082</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6277</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: hCG-β</rdfs:comment>
        <rdfs:label>CDX-1307 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007511 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007511">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005485"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007511</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine prepared as tumor cells are isolated from the lesion site of patients with recurrent or metastatic bladder cancer, and dendritic cells or macrophages are isolated from peripheral blood. The vaccine activates an immune response and the microenvironment of bladder cancer lesions, and improves the anti-recurrence treatment effect of bladder cancer. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05559177</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6278</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6278</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>chimeric exosomal tumor vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007512 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007512">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005487"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007512</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that treats patients with Binet Stage A Chronic Lymphocytic Leukemia (CLL) by using a fragment of Deoxyribonucleic acid (DNA) containing the sequence of their own immunoglobulin gene. The vaccine is designed to generate an immune response and shrink or slow the CLL.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00038415</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6279</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6279</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>CLL idiotypic DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007513 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007513</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine for patients with Locally Advanced, Triple-Negative Breast Cancer or ER-Positive, Her2-Negative Breast Cancer to receive ex vivo-generated tumor antigen-loaded dendritic cells (DCs), which can prime lymphocytes and regulate and maintain immune responses. The vaccine may boost T cell immunity targeted against breast cancer, enhance chemotherapy effectiveness and decrease tumor metastagenicity, and decrease the recurrence rates of LA TNBC and ER+/HER2- BC. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02018458</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6288</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:OGG_0000000006>931</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6288</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEF</rdfs:comment>
        <rdfs:comment>Gene name: WT-1</rdfs:comment>
        <rdfs:comment>Gene name: cyclin B1</rdfs:comment>
        <rdfs:label>cyclin B1/WT-1/CEF-loaded DC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007514 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007514</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous dendritic cells (DCs) fused with autologous acute myeloid leukemia (AML) cells, with potential immunostimulatory and antineoplastic activities. It is generated in vitro by mixing DCs and irradiated AML cells harvested from individual patients, in the presence of polyethylene glycol (PEG), to produce hybrid DC-leukemia fusion cells. The vaccine may elicit a cytotoxic T-lymphocyte (CTL)-mediated antitumor immune response against a broad array of AML-associated antigens, which may lead to AML cell lysis. When dendritic cells and tumor cells are brought together, the dendritic cells can stimulate immune responses against the tumor and, in some cases, cause the tumor to shrink. GM-CSF is a drug that stimulates white blood cells and is given with the DC AML Vaccine in an effort to enhance the effect of the vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C148214</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01096602</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03059485</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6374</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6374</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>DC/AML fusion vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007515 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007515">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005492"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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            </owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007515</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made using the participant&apos;s own blood cells. The vaccine will contain a virus called an adenovirus, similar the virus that causes the common cold. The dendritic cells contain survivin+, CD11c+, Human Leukocyte Antigen - antigen D Related (HLA-DR)+ by flow-cytometry. The vaccine is given in combination with G-CSF, T cells, and the CD34 progenitor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02851056</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6351</obo:IAO_0000119>
        <obo:OGG_0000000006>3123</obo:OGG_0000000006>
        <obo:OGG_0000000006>332</obo:OGG_0000000006>
        <obo:OGG_0000000006>3684</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6351</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD11</rdfs:comment>
        <rdfs:comment>Gene name: HLA-DR</rdfs:comment>
        <rdfs:comment>Gene name: survivin</rdfs:comment>
        <rdfs:label>dendritic cell survivin vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007516 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007516">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007516</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of dendritic cells pulsed with peptide epitopes that stimulate cytotoxic T lymphocyte anti-tumor activity. This vaccine is used to treat diffuse hemispheric glioma with a H3 G34 mutation that has come back (recurrent) and/or is growing, spreading, or getting worse (progressive). It is made with the patient&apos;s own white blood cells and peptide-pulsed dendritic cells, which may help the body build an effective immune response to kill tumor cells. It is combined with immunotherapy monoclonal antibodies, such as nivolumab and ipilimumab, which also may help the body&apos;s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C1987</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05457959</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6282</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6282</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>dendritic cell tumor peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007517 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007517">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005492"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007517</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine onsisting of autologous dendritic cells (DCs) fused with patient-derived plasma cell (multiple) myeloma cells with potential immunostimulatory and antineoplastic activities. Autologous DC/multiple myeloma fusions stimulate both helper and cytotoxic T-lymphocyte (CTL) responses through the presentation of internalized and newly synthesized tumor associated antigens (TAAs). This may promote cellular and humoral antitumor immune responses in patients with plasma cell myeloma. This vaccine uses Dendritic cell/myeloma fusions with granulocyte macrophage colony-stimulating factor (GM-CSF) adjuvant plus lenalidomide maintenance therapy. The dendritic cell myeloma vaccine may improve response in patients with multiple myeloma after autologous Hematopoietic Cell Transplant (HCT).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C158480</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02728102</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6323</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6323</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>dendritic cell/​myeloma fusion vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007518 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007518">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007518</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/517"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/768"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0004431"/>
        <rdfs:label>obsolete Melanoma DNA vaccine TA2M(TM) encoding tyrosinase peptides</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007519 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007519">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007519</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made of tumor cells and tumor stem cells that are isolated from a sample from a patient with glioblastoma multiforme. Dendritic cells are isolated from peripheral blood mononuclear cells and cultured. The tumor sample provides tumor specific antigens to prepare the dendritic vaccine. Cytotoxic lymphocytes are obtained from peripheral blood after dendritic vaccine administrations. Hematopoietic stem cells are harvested from closely related donor after granulocyte-colony-stimulating factor (G-CSF) administration. Allogeneic haploidentical hematopoietic stem cells are administered intrathecally, dendritic cells are administered subcutaneously, and cytotoxic lymphocytes are adminstered intrathecally. The combination of these treatments may control tumor cell quantity and target regulation of effector functions of tumor stem cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01759810</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6285</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6285</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>dendritic vaccine, allogeneic hematopoietic stem cells, cytotoxic lymphocytes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007520 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007520</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine from tumor cells and tumor stem cells that are isolated from a sample from a patient with glioblastoma multiforme. Dendritic cells are isolated from peripheral blood mononuclear cells and cultured. The tumor sample provides tumor specific antigens to prepare the dendritic vaccine. Cytotoxic lymphocytes are obtained from peripheral blood after dendritic vaccine administrations. Hematopoietic stem cells are harvested from closely related donor after granulocyte-colony-stimulating factor (G-CSF) administration. Autologous haploidentical hematopoietic stem cells are administered intrathecally, dendritic cells are administered subcutaneously, and cytotoxic lymphocytes are adminstered intrathecally. The combination of these treatments may control tumor cell quantity and target regulation of effector functions of tumor stem cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01759810</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6286</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6286</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>dendritic vaccine, autologous hematopoietic stem cells, cytotoxic lymphocytes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007521 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007521</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine based on ex vivo genetic modifications in combination with known tumor-specific antigens may substantially enhance the activation potential of tumor-specific T cells with improved benefit to patients. This DC vaccine is based on autologous DCs pulsed with genetically modified tumor cells or related antigens such as neoantigens to induce a strong anti-tumor immunity. The patient will receive intravenous cyclophosphamide (200 mg/m2) or oral (cytoxan) before the vaccine, followed by DC vaccine and intravenous bevacizumab (15 mg/kg).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03914768</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6301</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6301</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>DIPG and GMB Immunomodulatory DC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007522 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007522">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007522</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with PEG fusions generated from allogeneic dendritic cells and autologous tumor-derived cells with GM-CSF and Il-4. The vaccine is irradiated, frozen, and thawed before being administered to patients with AJCC Stage IV Renal Cell Carcinoma. The vaccine could have and effect on the immune system and cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00625755</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6287</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6287</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>electrofusion DC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007523 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007523">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007523</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic allogeneic cancer vaccine. Melanoma theraccine typically consists of lysed melanoma cells obtained from several melanoma cell lines combined with an adjuvant (such as DETOX or RIBI). This agent may be combined with immunomodulatory cytokines such as interferon alpha. Melanoma theraccine may induce a rise in the level of cytotoxic T-lymphocyte precursors.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>Melanoma Theraccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4989</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/522</obo:IAO_0000233>
        <obo:OGG_0000000006>282617</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4989</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IFNL3</rdfs:comment>
        <rdfs:label>melanoma Theraccine vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007524 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007524">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007524</metadata:prefixIRI>
        <obo:IAO_0000115>A therapeutic melanoma vaccine consisting of autologous dendritic cells (DCs) pulsed with antigens from lethally irradiated autologous tumor cells derived from a patient-specific, continuously proliferating and melanoma-initiating cell line and suspended in a solution containing the cytokine granulocyte-macrophage colony stimulating factor (GM-CSF), with potential immunostimulatory and antineoplastic activities. Upon subcutaneous administration, melapuldencel-T may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against the patient&apos;s repertoire of melanoma-associated antigens, particularly tumor stem cell antigens, found in the irradiated autologous cancer cells. As an immunostimulant, GM-CSF enhances the activation of dendritic cells (DCs) and promotes antigen presentation to both B- and T-lymphocytes.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5014</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/523</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5014</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Melapuldencel-T vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007525 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007525">
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007525</metadata:prefixIRI>
        <obo:IAO_0000115>A multipeptide cancer vaccine comprised of 12 melanoma peptides restricted by Class I MHC (12MP), plus a tetanus helper peptide</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5261</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/524</obo:IAO_0000233>
        <obo:OGG_0000000006>22178</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5261</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TRP-1</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>MELITAC 12.1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007526 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007526">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007526</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of estrogen receptor alpha (ERa; estrogen receptor 1; ESR1) mutant peptides, combined with the immunoadjuvants granulocyte-macrophage colony-stimulating factor (GM-CSF) and montanide ISA, with potential immunomodulating and antineoplastic activities. ESR1 mutant peptides in the ESR1 peptides/GM-CSF/montanide ISA vaccine may activate the immune system to induce an immune response against tumor cells expressing these ESR1 mutations.  Cancer peptides used in this vaccine are derived from the estrogen receptor and are combined with the adjuvant Montanide ISA and GM-CSF to enhance their immune response. The vaccine may improve outcomes of patients with endocrine resistant breast cancer. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C175590</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04270149</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6289</obo:IAO_0000119>
        <obo:OGG_0000000006>2099</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6289</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ESR1</rdfs:comment>
        <rdfs:label>ESR1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007527 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007527">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007527</metadata:prefixIRI>
        <obo:IAO_0000115>A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2 with potential immunostimulating and antineoplastic activities. Upon administration, monoclonal antibody 4B5 anti-idiotype vaccine may elicit both cellular and humoral immune responses against GD2- expressing tumor cells. GD2 is a glycosphingolipid (ceramide and oligosaccharide) that may be highly expressed by melanomas and other neuroectodermal tumors, while only minimally expressed by normal tissues.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5039</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/535</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5039</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>monoclonal antibody 4B5 anti-idiotype vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007528 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007528">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007528</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine consisting of a plasmid DNA encoding the murine melanoma-associated antigen gp100. Upon administration, expressed gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune response against tumor cells that express the gp100 antigen, resulting in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5386</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/539</obo:IAO_0000233>
        <obo:OGG_0000000006>20431</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5386</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Pmel17</rdfs:comment>
        <rdfs:label>Mouse gp100 Plasmid DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007529 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007529">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007529</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/543"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0004614"/>
        <rdfs:label>obsolete mRNA-Electroporated Dendritic Cells Vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007530 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007530">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007530</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine directed against the soluble protein idiotype of an individual follicular lymphoma with potential antineoplastic activity. The vaccine may induce an idiotype-specific cytotoxic T-lymphocyte (CTL) response against follicular lymphoma cells expressing the idiotype, resulting in tumor cell lysis. Idiotypic vaccinations have the capacity of inducing an idiotype- and tumor-specific immune response, inducing specific immune responses able to kill in vivo follicular lymphoma cells, and prolonging survival of responding patients. This vaccine may contribute to preventing relapse indefinitely in responding patients.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C71036</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00530140</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6290</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6290</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>follicular lymphoma, patient-specific, soluble protein idiotype vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007531 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007531">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007531</metadata:prefixIRI>
        <obo:IAO_0000115>A plasmid DNA vaccine encoding the mouse tumor associated antigen tyrosinase-related protein-2 (TYRP2) with potential immunostimulating and antineoplastic activities. Upon administration, murine TYRP2 plasmid DNA vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing TYRP2; this vaccine may also induce an immune response against tyrosinase-related protein-1 (TYRP1). TYRP2 and TYRP1, melanosomal membrane glycoproteins upregulated in melanoma cells, are involved in melanin synthesis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5310</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/558</obo:IAO_0000233>
        <obo:OGG_0000000006>1638</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5310</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: DCT</rdfs:comment>
        <rdfs:label>Murine TYRP2 plasmid DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007532 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007532">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007532</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing dendritic cells (DCs) that are transfected with messenger RNA (mRNA) encoding human telomerase reverse transcriptase (hTERT) and LAMP. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5276</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/446</obo:IAO_0000233>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5276</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>hTERT-LAMP mRNA-loaded autologous dendritic cell vaccine GRNVAC1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007533 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007533">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007533</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant 19-residue peptide vaccine consisting of amino acids 161 through 180 of the cancer/testis (CT) antigen. ESO-1 (161-180) peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for ESO-1, resulting in decreased tumor growth. ESO-1 is expressed in a variety of cancers, including melanoma, breast, bladder, prostate, and hepatocellular cancers. (NCI04) (NCIT_C28775).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5264</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/66</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5264</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>ESO-1 (161-180) peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007534 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007534</metadata:prefixIRI>
        <obo:IAO_0000115>A 9-residued peptide vaccine consisting of amino acids 157 through 165 of the cancer/testis (CT) antigen ESO-1. Modified at position 165 (cysteine to valine) to improve immunogenicity, ESO-1:157-165(165v) peptide administered as a vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for ESO-1, resulting in decreased tumor growth. ESO-1 is expressed in a variety of cancers, including melanoma, breast, bladder, prostate, and hepatocellular cancers.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5473</obo:IAO_0000119>
        <obo:IAO_0000119>https://pubmed.ncbi.nlm.nih.gov/?term=ESO-1%3A157-165%28165V%29+Peptide</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/68</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5473</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>ESO-1:157-165(165V) peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007535 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007535">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007535</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant virus-based vaccine that contains various peptide antigens. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues. Strong CD8 T cell responses may be induced after prolonged immunization and have been associated with tumor regression.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:15757474</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5031</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/129</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:OGG_0000000006>634</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5031</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM1</rdfs:comment>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>fowlpox virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007536 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007536">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007536</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine against the immunomodulatory enzyme indoleamine 2,3-dioxygenase (IDO), with potential immunomodulating and antineoplastic activities. Vaccination with indoleamine 2,3-dioxygenase peptide vaccine may activate the immune system to induce an immune response against IDO-expressing cells. This may increase and restore the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, and T-lymphocytes, and may eradicate IDO-expressing tumor cells. IDO, a cytosolic enzyme responsible for tryptophan catabolism and conversion of tryptophan into kynurenine, is overexpressed by a variety of tumor cell types and antigen presenting cells (APCs) and plays an important role in immunosuppression; Tryptophan depletion inhibits T-lymphocyte proliferation and activation, and suppresses the immune system</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5144</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/469</obo:IAO_0000233>
        <obo:OGG_0000000006>3620</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5144</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IDO1</rdfs:comment>
        <rdfs:label>Indoleamine 2,3-dioxygenase Peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007537 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007537">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007537</metadata:prefixIRI>
        <obo:IAO_0000115>A conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity. Folate-FITC binds to folate receptors, which are overexpressed on the surfaces of many cancer cells including kidney and ovarian cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate, circulating anti-fluorescein antibodies may recognize and bind to the FITC moiety, resulting in antibody-dependent cellular cytotoxicity. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22855837</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5317</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/128</obo:IAO_0000233>
        <obo:OGG_0000000006>2348</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5317</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FOLR1</rdfs:comment>
        <rdfs:label>Folate-FITC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007538 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007538">
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        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007538</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant vaccinia virus encoding the tumor-associated gene MAGE-1 that is contaminated with bovine viral diarrhea virus (BVDV). The MAGE-1 gene is a member of the melanoma antigen-encoding gene family which is expressed in various malignant tumors such as hepatocellular carcinoma and germ cell tumors in addition to melanoma. Vaccination with vaccinia virus expressing human MAGE-1 may generate antitumoral T-cell responses. BVDV is an RNA pestivirus that may contaminate vaccines due to its presence in the fetal calf serum used as a growth supplement in the tissue culture of mammalian cells used in vaccine production.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>MAGE-1 Vaccinia Contaminated with BVDV</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5157</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/488</obo:IAO_0000233>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5157</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA1</rdfs:comment>
        <rdfs:label>MAGE-1 Vaccinia contaminated with bovine viral diarrhea virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007539 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007539">
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            </owl:Restriction>
        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007539</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide cancer vaccine comprised of a peptide derived from the human melanoma antigen A3 (MAGE-A3), with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-A3 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-A3, resulting in tumor cell lysis. MAGE-A3, a tumor-associated antigen (TAA), is overexpressed by a variety of cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5395</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/491</obo:IAO_0000233>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5395</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:label>MAGE-A3 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007540 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007540</metadata:prefixIRI>
        <obo:IAO_0000115>An oncolytic adenoviral vaccine composed of a replication-defective, E1- and E3-deleted adenovirus serotype 5 (Ad5) with a transgene encoding the human melanoma antigen A3 (MAGE-A3), with potential antineoplastic activity. Upon administration, MAGE-A3-expressing adenovirus type 5 vaccine selectively replicates in cancer cells and expresses MAGE-A3. This induces an immune response against tumor cells expressing the MAGE-A3 antigen, which leads to tumor cell death. The tumor-associated antigen MAGE-A3 is overexpressed by a variety of cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5336</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/492</obo:IAO_0000233>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5336</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:label>MAGE-A3-expressing Adenovirus Type 5 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007541 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007541">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005492"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_6536"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007541</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine consisting of multiple epitopes derived from the human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, with potential immunostimulating and antineoplastic activities. hTERT I540/R572Y/D988Y multipeptide vaccine contains strongly antigenic peptide epitopes I540 (9-mer), R572Y (9-mer) and D988Y (10-mer). Vaccination with this agent may elicit a cytotoxic T cell (CTL) response against telomerase-expressing tumor cells. Directly linked to tumorigenesis, telomerase is expressed in the majority of human cancer cells but is infrequently expressed in normal cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5191</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/439</obo:IAO_0000233>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_6536"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5191</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>hTERT I540/R572Y/D988Y multipeptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007542 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007542">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005427"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005492"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_6536"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007542</metadata:prefixIRI>
        <obo:IAO_0000115>A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with tumor-derived clonal immunoglobulin (Ig) with potential immunostimulatory and antineoplastic activities. Upon administration, idiotype-pulsed autologous dendritic cell vaccine APC8020, containing idiotype (Id) protein structures that can be recognized by antibodies and by CD41 T lymphocytes and CD81 T lymphocytes, may stimulate antitumoral cytotoxic T lymphocyte (CTL) and antibody responses against Id-expressing tumor cells. The Id represents the unique antigenic determinants in the variable regions of the clonal Ig.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5344</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/460</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_6536"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9538"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5344</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Idiotype-pulsed autologous dendritic cell vaccine APC8020</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007543 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007543">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003140"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_3908"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007543</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made from tumor-specific neopeptides resulting from frameshift mutations in tumor cells, so-called Frames, present potentially potent targets for the immune system and can be utilized in therapeutic anti-cancer vaccination with the intention to synergize in their effect with immune checkpoint inhibitors. The personalized vaccine FRAME-001 based on a patient&apos;s Framome and selection of Frame peptides in advanced NSCLC cancer patients after standard first line treatment consisting of immune checkpoint inhibitor pembrolizumab as monotherapy or combined with chemotherapy (carboplatin/cisplatin and pemetrexed/paclitaxel) could help treat patients with non-small cell lung cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04998474</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6291</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3908"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6291</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>FRAME-001 personalized vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007544 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007544">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005498"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9261"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007544</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the gene for the CD4 epitope-rich C-terminal domain of the Epstein Barr Virus (EBV) antigen EBNA1 and fused to the full-length of the EBV-associated antigen latent membrane protein 2 (LMP2), with potential immunostimulatory and antineoplastic activities. Upon administration, MVA EBNA1/LMP2 vaccine may elicit a cytotoxic T-cell immune response against cancer cells expressing EBNA1 and LMP2. Multi-antigen vaccine therapy may be more efficacious than single-antigen therapy vaccine therapy. EBNA1, a sequence-specific DNA binding protein, plays an important role in EBV episomal genome maintenance and gene transactivation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5460</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/565</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:OGG_0000000006>55</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9261"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5460</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ACP3</rdfs:comment>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>MVA-PSA/PAP Prostate Cancer Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007545 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007545">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9261"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007545</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the gene for the CD4 epitope-rich C-terminal domain of the Epstein Barr Virus (EBV) antigen EBNA1 and fused to the full-length of the EBV-associated antigen latent membrane protein 2 (LMP2), with potential immunostimulatory and antineoplastic activities. Upon administration, MVA EBNA1/LMP2 vaccine may elicit a cytotoxic T-cell immune response against cancer cells expressing EBNA1 and LMP2. Multi-antigen vaccine therapy may be more efficacious than single-antigen therapy vaccine therapy. EBNA1, a sequence-specific DNA binding protein, plays an important role in EBV episomal genome maintenance and gene transactivation. (NCIT_C91076).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5314</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/560</obo:IAO_0000233>
        <obo:OGG_0000000006>3783709</obo:OGG_0000000006>
        <obo:OGG_0000000006>5698</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9261"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5314</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EBNA-1</rdfs:comment>
        <rdfs:comment>Gene name: PSMB9</rdfs:comment>
        <rdfs:label>MVA-EBNA1/LMP2 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007546 -->

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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007546</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine containing amino acids residues from 340 through 349 of the latent membrane protein-2 (LMP-2) of the Epstein-Barr virus (EBV) with potential immunostimulating and antineoplastic activities. LMP-2, an EBV transmembrane protein, is expressed in various malignancies including nasopharyngeal cancer and EBV-positive Hodgkin&apos;s disease. Vaccination with the LMP-2:340-349 peptide may boost the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against LMP-2 producing cells, resulting in cell lysis and inhibition of cancer cell proliferation</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5466</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/482</obo:IAO_0000233>
        <obo:OGG_0000000006>5689</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9261"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5466</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PSMB9</rdfs:comment>
        <rdfs:label>LMP-2:340-349 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007547 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007547">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007547</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine containing amino acids residues from 419 through 427 of the latent membrane protein-2 (LMP-2) of the Epstein-Barr virus (EBV) with potential immunostimulating and antineoplastic activities. LMP-2, an EBV transmembrane protein, is expressed in various malignancies including nasopharyngeal cancer and EBV-positive Hodgkin&apos;s disease. Vaccination with the LMP-2:49-427 peptide may boost the immune system to mount a specific cytotoxic T-lymphocyte response against LMP-2 producing cells, resulting in cell lysis and inhibition of cancer cell proliferation.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5479</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/483</obo:IAO_0000233>
        <obo:OGG_0000000006>5689</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9261"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5479</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PSMB9</rdfs:comment>
        <rdfs:label>LMP-2:419-427 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007548 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007548">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007548</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of synthetic peptides derived from human melanoma antigen A1 (MAGE-A1), human melanoma antigen A3 (MAGE-A3) and cancer-testis antigen NY-ESO-1 with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-A1/MAGE-A3/NY-ESO-1 peptides vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-A1, MAGE-A3 and NY-ESO-1, resulting in tumor cell lysis. The MAGE-A1, MAGE-A3, and NY-ESO-1 tumor-associated antigens (TAAS) are overexpressed by a variety of cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5263</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/490</obo:IAO_0000233>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5263</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA1</rdfs:comment>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:label>MAGE-A1/MAGE-A3/NY-ESO-1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007549 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007549">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007549</metadata:prefixIRI>
        <obo:IAO_0000115>A trivalent cancer vaccine containing the ganglioside lactones GM2, GD2 and GD3 conjugated with the immunostimulant keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with GM2 lactone/GD2 lactone/GD3 lactone-KLH conjugate trivalent vaccine may elicit antibodies against tumor cells expressing any of these epitopes, resulting in an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing these gangliosides. GM2, GD2 and GD3 are tumor associated antigens (TAAs) that are overexpressed in a variety of tumor cell membranes.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5532</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/178</obo:IAO_0000233>
        <obo:OGG_0000000006>117189</obo:OGG_0000000006>
        <obo:OGG_0000000006>2760</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5532</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM2A</rdfs:comment>
        <rdfs:comment>Gene name: GRDX</rdfs:comment>
        <rdfs:label>GM2/GD2/GD3 Lactone-KLH conjugate trivalent vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007550 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007550">
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007550</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing four HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this vaccine are derived from ring finger protein 43 (RNF43); translocase of outer mitochondrial membrane 34 (TOMM34); and vascular endothelial growth factor receptors (VEGFR) 1 and 2. Upon administration, HLA-A*2404-restricted RNF43-TOMM34-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing RNF43, TOMM34, and VEGFR 1 and 2 peptides, resulting in tumor cell lysis and decreased tumor growth. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenic peptide immunogenicity</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5429</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/421</obo:IAO_0000233>
        <obo:OGG_0000000006>10953</obo:OGG_0000000006>
        <obo:OGG_0000000006>3791</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5429</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KDR</rdfs:comment>
        <rdfs:comment>Gene name: TOMM34</rdfs:comment>
        <rdfs:label>HLA-A*2404-Restricted RNF43-TOMM34-VEGFR1-VEGFR2 multipeptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007551 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007551">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007551</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine comprised of synthetic HLA-A1, -A2 and -B35 restricted survivin epitopes combined with the adjuvant Montanide ISA-51 with potential antineoplastic activity. Upon administration, HLA-A1, A2, B35-restricted survivin peptides/Montanide ISA-51 vaccine may stimulate a cytotoxic T cell response against tumor cells that overexpress survivin, resulting in tumor cell lysis. Montanide ISA-51, also known as incomplete Freund&apos;s adjuvant or IFA, is a stabilized water-in-oil emulsion adjuvant containing mineral oil with mannide oleate added as a surfactant that non-specifically stimulates cell-mediated immune responses to antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000118>HLA-A1, A2, B35-Restricted Survivin Peptides/Montanide ISA-51 Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5120</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/422</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5120</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Survivin</rdfs:comment>
        <rdfs:label>HLA-A1, A2, B35-restricted survivin peptide/montanide ISA-51 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007552 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007552">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007552</metadata:prefixIRI>
        <obo:IAO_0000115>A dendritic cell (DC) vaccine containing ex vivo expanded autologous DCs obtained from a patient with leukemia with potential immunostimulating activity. Upon reintroduction into the host, the host dendritic cell vaccine-001 MSSM/BIIR may stimulate the immune system to mount a leukemia-specific cytotoxic T lymphocyte (CTL) response.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5246</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/428</obo:IAO_0000233>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5246</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:label>host dendritic cell vaccine-001 MSSM/BIIR</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007553 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007553">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007553</metadata:prefixIRI>
        <obo:IAO_0000115>A multi-peptide cancer vaccine with potential immunostimulating and antineoplastic activities. IMT-1012 immunotherapeutic vaccine contains twelve different synthetic peptides or tumor associated antigens (TAAs), including cyclin I (CCNI), cyclin-dependent kinase CDC2, EDDRI and TACE/ADAM17, each of which is involved in a different pathway associated with tumor growth, survival, and metastasis. Each antigen in the vaccine elicits a specific cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing that antigen. This multi-antigen/multi-pathway targeting strategy provides broad immunotherapeutic coverage with respect to tumor complexity and heterogeneity and may result in enhanced vaccine efficacy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5048</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/464</obo:IAO_0000233>
        <obo:OGG_0000000006>10983</obo:OGG_0000000006>
        <obo:OGG_0000000006>983</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5048</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CCNI</rdfs:comment>
        <rdfs:comment>Gene name: CDK1</rdfs:comment>
        <rdfs:label>IMT-1012 Immunotherapeutic vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007554 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007554">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007554</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing four HLA-A0201-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Vaccine peptide epitopes are derived from the tumor associated antigens (TAAs) tyrosinase-related protein 2 (TRP2), glycoprotein 100 (gp100), Ephrin receptor A2 (EphA2) and human epidermal growth factor receptor 2 (HER2). Upon administration, HLA-A0201-restricted TRp2-gp100-EphA2-HER2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against TRP2-gp100-EphA2-HER2-expressing tumor cells, resulting in tumor cell lysis and decreased tumor cell proliferation. HLA-A0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5355</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/309</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5355</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:comment>Gene name: PMEL</rdfs:comment>
        <rdfs:label>HLA-A0201-Restricted TRP2-gp100-EphA2-HER2 multipeptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007555 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007555">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007555</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing three HLA-A0201-restricted peptide epitopes with potential immunostimulatory, antiangiogenic, and antitumor activities. Vaccine peptide epitopes are derived from the tumor associated antigen (TAA) URLC (up-regulated in lung cancer 10) and vascular endothelial growth factor receptors (VEGFR) 1 and 2. Upon administration, HLA-A0201-restricted URLC10-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against URLC10-expressing tumor cells and the tumor microvasculature expressing VEGFR 1 and 2 peptides; this may result in tumor cell lysis, the inhibition of tumor angiogenesis, and decreased tumor growth. HLA-A0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5017</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/417</obo:IAO_0000233>
        <obo:OGG_0000000006>3791</obo:OGG_0000000006>
        <obo:OGG_0000000006>54742</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5017</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KDR</rdfs:comment>
        <rdfs:comment>Gene name: LY6K</rdfs:comment>
        <rdfs:label>HLA-A*0201-Restricted URLC10-VEGFR1-VEGFR2 multipeptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007556 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007556">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007556</metadata:prefixIRI>
        <obo:IAO_0000115>A live-attenuated, double-deleted strain of the Gram-positive bacterium Listeria monocytogenes (Lm) encoding a mutant form of the tumor associated antigens, epidermal growth factor receptor (EGFRvIII) and the cancer/testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, live-attenuated Listeria monocytogenes encoding EGFRvIII-NY-ESO-1 vaccine targets dendritic cells and expresses EGFRvIII and NY-ESO-1. This promotes both a potent innate immune response and an adaptive immune response involving the recruitment and activation of T lymphocytes against EGFRvIII and NY-ESO-1-expressing tumor cells, which results in tumor cell lysis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4991</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/480</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>1956</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4991</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:comment>Gene name: EGFR</rdfs:comment>
        <rdfs:label>live-attenuated Listeria monocytogenes-encoding EGFRvIII-NY-ESO-1 vaccine ADU-623</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007557 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007557">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007557</metadata:prefixIRI>
        <obo:IAO_0000115>A multivalent vaccine comprised of the epitope antigens of Globo H hexasaccharide 1 (Globo H), GM2 ganglioside, Lewis-Y, MUC1-32-mer, TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin, with potential antineoplastic activity. The antigens included in this vaccine are associated various cancer cells. Vaccination with this multivalent vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5104</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/173</obo:IAO_0000233>
        <obo:OGG_0000000006>	4582</obo:OGG_0000000006>
        <obo:OGG_0000000006>2760</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5104</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM2A</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>Globo H-GM2-Lewis-y-MUC1-32-mer-TF(c)-Tn(c)-KLH conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007558 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007558">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007558</metadata:prefixIRI>
        <obo:IAO_0000115>Peripheral blood lymphocytes (PBL) transfected to express MOv have been designed for possible use in autologous adoptive cellular immunotherapy of ovarian adenocarcinomas that overexpress folate-binding protein. MOv-PBLs express MOv-gamma (MOv), a chimeric receptor gene product derived from a recombinant gene encoding the variable region of murine monoclonal antibody MOv18 against folate-binding protein (FBP), often overexpressed in human ovarian cancer cells, and the human gene encoding the IgG and IgE Fc receptor gamma subunit. Autologous vaccination with these PBLs stimulates a host cytotoxic T lymphocyte response against ovarian cancer cells that overexpress FBP.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5335</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/541</obo:IAO_0000233>
        <obo:OGG_0000000006>4343</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5335</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MOV10</rdfs:comment>
        <rdfs:label>MOv-PBL Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007559 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007559">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1964"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007559</metadata:prefixIRI>
        <obo:IAO_0000115>An attenuated oncolytic vaccinia virus encoding the light-emitting fusion protein Renilla luciferase-Aequorea green fluorescent protein (RUC-GFP) with potential bioluminescent and antineoplastic activities. Upon administration, light-emitting oncolytic vaccinia virus GL-ONC1 specifically enters tumor cells due to the permeable nature of the tumor vasculature. Once inside the cell, the virus replicates, resulting in tumor cell lysis and the release of mature viral particles into the tumor microenvironment. Released viral particles may then infect and destroy neighboring tumor cells. In addition, the release of tumor-associated antigens (TAAs) by lysed tumor cells into the bloodstream may activate the immune system to mount a cytotoxic T lymphocyte (CTL) response against the tumor. The expression of RUC-GFP by this agent allows for both detection and monitoring of virally infected tumor cells in vivo and vitro with luciferase-mediated bioluminescence imaging and fluorescence imaging techniques.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5385</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/477</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1964"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5385</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Tumor Associated Antigen</rdfs:comment>
        <rdfs:label>light-emitting Oncolytic Vaccinia virus GL-ONC1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007560 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007560">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005489"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1993"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007560</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing an HLA-A*0201-restricted vascular endothelial growth factor receptor 1 (VEGFR1) peptide (sequence: TLFWLLLTL) with potential immunostimulatory and antitumor activities. Upon administration, HLA-A*0201-restricted VEGFR1-derived peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing VEGFR1, resulting in tumor cell lysis and decreased tumor growth. HLA-A*0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5413</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/418</obo:IAO_0000233>
        <obo:OGG_0000000006>3791</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1993"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_219"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5413</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KDR</rdfs:comment>
        <rdfs:label>HLA-A*0201-Restricted VEGFR1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007561 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007561">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007561</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant fowlpox virus encoding human prostate-specific antigen (PSA) and TRICOM, a combination of three immunostimulants (i.e., B7.1, ICAM-1, and LFA-3). Administration of this agent may induce a cytotoxic T cell response against PSA-expressing tumor cells. Dendritic cells infected with TRICOM vectors greatly enhance naive T-cell activation and peptide-specific T-cell stimulation. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5038</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/132</obo:IAO_0000233>
        <obo:OGG_0000000006>354</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5038</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KLK3</rdfs:comment>
        <rdfs:label>Fowlpox-PSA-TRICOM Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007562 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007562">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000186"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007562</metadata:prefixIRI>
        <obo:IAO_0000115>A prostate cancer vaccine containing mRNAs encoding prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), prostate stem cell antigen (PSCA) and six-transmembrane epithelial antigen of the prostate (STEAP), with potential antitumor activity. Upon administration, mRNA-derived prostate cancer vaccine CV9103 may stimulate the immune system to mount a cytotoxic T lymphocyte response (CTL) against PSA-, PSMA-, PSCA- and STEAP-expressing prostate tumor cells. The mRNA used in this vaccine is modified and formulated to have enhanced translational potency and adjuvant activities. PSA, PSMA, PSCA and STEAP may be upregulated in prostate cancer cells; their expression in prostate cancer has been correlated with disease progression.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5369</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/542</obo:IAO_0000233>
        <obo:OGG_0000000006>26872</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000728"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5369</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: STEAP1</rdfs:comment>
        <rdfs:label>mRNA-Derived Prostate Cancer Vaccine CV9103</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007563 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007563">
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007563</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5126</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/546</obo:IAO_0000233>
        <obo:OGG_0000000006>4583</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5126</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC2</rdfs:comment>
        <rdfs:label>MUC-2-Globo H-KLH Conjugate Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007564 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007564">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005426"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005430"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005496"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1993"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007564</metadata:prefixIRI>
        <obo:IAO_0000115>A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5292</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/194</obo:IAO_0000233>
        <obo:OGG_0000000006>7124</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1993"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5292</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TNF</rdfs:comment>
        <rdfs:label>Golnerminogene Pradenovec vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007565 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007565">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007565</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide vaccine comprised of synthetic HLA-A2- and HLA-A3-binding peptides, derived from amino acid sequences of fibroblast growth factor-5 (FGF-5), combined with the adjuvant Montanide ISA-51 with potential antineoplastic activity. HLA-A2, A3-restricted FGF-5 peptides contain motifs recognized by the MHC class I molecules HLA-A2 and HLA-A3 and may stimulate a cytotoxic T-cell response against tumor cells that overexpress FGF-5. Montanide ISA-51, a stabilized water-in-oil emulsion adjuvant containing mineral oil with mannide oleate added as a surfactant, non-specifically stimulates cell-mediated immune responses to antigens</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5465</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/424</obo:IAO_0000233>
        <obo:OGG_0000000006>2250</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5465</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FGF5</rdfs:comment>
        <rdfs:label>HLA-A2, A3-Restricted FGF-5 Peptides/Montanide ISA-51 Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007566 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007566">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007566</metadata:prefixIRI>
        <obo:IAO_0000115>A naturally occurring 9-residue peptide of fibroblast growth factor 5 (FGF-5). Recognized by tumor infiltrating cytotoxic T lymphocytes originally isolated from a renal cell carcinoma that overexpressed FGF-5, FGF-5:172-176/217-220 peptide activates various cytotoxic CD8 lymphocytes in an HLA-restricted manner. Overexpressed in several cancer cell lines, FGF-5 is a tumor-associated antigen that may be useful in cancer immunotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5498</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/134</obo:IAO_0000233>
        <obo:OGG_0000000006>4108</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5498</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA9</rdfs:comment>
        <rdfs:label>G250 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007567 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007567">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005495"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007567</metadata:prefixIRI>
        <obo:IAO_0000115>A synthetic peptide derived from the protein ESW/FLI1 type 1 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing&apos;s sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-1 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FL1 type 1 fusion protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5509</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/52</obo:IAO_0000233>
        <obo:OGG_0000000006>	253970502</obo:OGG_0000000006>
        <obo:OGG_0000000006>100306940</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5509</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EWSR1</rdfs:comment>
        <rdfs:comment>Gene name: FL1</rdfs:comment>
        <rdfs:label>EF-1 Peptide Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007568 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007568</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of a 43 amino acid epitope from glycoprotein MUC1 (mucin 1) and the synthetic Toll-like receptor 4 (TLR-4) agonist PET lipid A encapsulated in cholesterol/dipalmitoylphosphatidylcholine (DPPC)/dimyristoylphosphatidylglycerol (DMPG) liposomes, with potential immunostimulatory and antineoplastic activities. The MUC1 epitope is composed of two 20 amino glycosylated VNTR (various number tandem repeats) from human MUC1A and including 6 glycosylated sites modified by Tn (alfa-N-acetyl-D-galactosamine). Immunization of liposomal MUC1/PET-lipid A vaccine results in an antibody as well as a cytotoxic T-lymphocyte (CTL) response against hypoglycosylated MUC1 expressing tumor cells. The tumor associated antigen MUC1, a type I transmembrane protein, is overexpressed and aberrantly glycosylated in a variety of tumor cells. As a vaccine adjuvant, PET lipid A, also known as penta erythritol lipid A, stimulates both cellular and humoral responses to the vaccine antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5488</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/479</obo:IAO_0000233>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5488</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>liposomal MUC1/PET-lipid A vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007569 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007569">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007569</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5345</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/493</obo:IAO_0000233>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5345</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGEA3</rdfs:comment>
        <rdfs:label>MAGE-A3/HPV 16 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007570 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007570">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005494"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007570</metadata:prefixIRI>
        <obo:IAO_0000115>A peptide derived from the tumor suppressor protein Von Hippel-Lindau (VHL). This peptide, sequence: MEAGRPRPCCAR, was constructed based on a frameshift mutation of one of the VHL gene products; the more abundant protein VHLp18(MEA) (where MEA stands for three amino acids, Met-Glu-Ala). Vaccination with FrSh61(MEA)VHL33 peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5236</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/133</obo:IAO_0000233>
        <obo:OGG_0000000006>7428</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5236</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: VHL</rdfs:comment>
        <rdfs:label>FrSh61 (MEA) VHL33 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007571 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007571">
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007571</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine based on virus-like replicon particles (VRP) packaged with an alphaviral vector encoding the extracellular domain (ECD) and transmembrane (TM) regions of the human epidermal growth factor receptor 2 (EGFR2, NEU or HER2), with potential antineoplastic activity. After immunization with HER2 ECD+TM virus-like replicon particles vaccine AVX901, the VRPs infect cells and express HER2 ECD+TM protein that may activate the immune system to elicit a cytotoxic T-lymphocyte (CTL) response against HER2-expressing tumor cells. The alphaviral replicon of this vaccine is an attenuated strain of the Venezuelan equine encephalitis virus (VEEV) in which 3 of the 7 viral genes were substituted with a truncated HER2 gene to create a self-amplifying replicon RNA. HER2, a tyrosine kinase involved in several cell growth signaling pathways, is dysregulated or overexpressed in a wide variety of cancer cell types.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Justin Song</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi (Penny) Pan</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5442</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/305</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5442</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>HER2 ECD+TM virus-like replicon particles vaccine AVX901</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007572 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007572">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007572</metadata:prefixIRI>
        <obo:IAO_0000115>A replication-competent oncolytic adenovirus encoding the murine pro-inflammatory cytokine interleukin-12 (IL-12) gene and two suicide fusion genes, a yeast cytosine deaminase (yCD) and a mutant form of herpes simplex virus type 1 thymidine kinase (HSV-1 TKSR39), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration of Ad5-yCD/mutTKSR39rep-hIL12, the adenovirus selectively infects and replicates in tumor cells, which results in direct tumor cell lysis. Synergistically, IL-12 expressed by the adenovirus may activate the immune system by promoting the activation of natural killer cells (NKs), inducing secretion of interferon-gamma (IFN-g) and inducing cytotoxic T-lymphocyte (CTL) responses against tumor cells, which may result in immune-mediated tumor cell death, inhibition of tumor cell proliferation and inhibition of tumor angiogenesis. In addition, Ad5-yCD/mutTKSR39rep-hIL12-infected cancer cells express yCD and TKSR39; upon administration of the prodrugs 5-fluorocytosine (5-FC) and valganciclovir (vGCV), the yCD and HSV-1 TKSR39 activate these prodrugs to form 5-fluorouracil (5-FU) and ganciclovir, respectively. 5-FU gets converted to 5-fluoro-uridine monophosphate (5-FUMP) and subsequently to 5-fluoro-deoxyuridine monophosphate (5-FdUMP); 5-FdUMP irreversible inhibits thymidylate synthase, inhibits deoxythymidine triphosphate (dTTP) formation and halts DNA synthesis. Once phosphorylated intracellularly, ganciclovir triphosphate competitively inhibits deoxyguanosine triphosphate (dGTP) incorporation into DNA and inhibits DNA synthesis.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5303</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/89</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5303</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IL12A</rdfs:comment>
        <rdfs:comment>Gene name: IL12B</rdfs:comment>
        <rdfs:label>Ad5-yCD/mutTKSR39rep-hIL12 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007573 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007573">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007573</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5324</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5324</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Ad5F35-LMP1/LMP2-Transduced autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007574 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007574">
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007574</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5534</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5534</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Alpha Fetoprotein Plasmid DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007575 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007575">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007575</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4995</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4995</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>ALVAC-CEA (6D)-B7.1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007576 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007576">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007576</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5085</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0007283"/>
        <rdfs:label>obsolete Autologous Dendritic Cell Vaccine ACT2001</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007577 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007577">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007577</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0007289"/>
        <rdfs:label>obsolete Autologous Dendritic Cell-Tumor Fusion Vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007578 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007578">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007578</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4051</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4051</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous dendritic cells (DCs) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007579 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007579">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007579</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0007301"/>
        <rdfs:label>obsolete Autologous Immunoglobulin Idiotype-KLH Conjugate Vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007580 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007580">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007580</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3981</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>3981</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>autologous monocyte-derived mature DCs pulsed with p53, survivin and telomerase-derived peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007581 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007581">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007581</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4029</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4029</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacille Calmette Guerin for melanoma of lower extremity vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007582 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007582">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000886"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007582</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4028</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/776</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000886"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4028</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus Calmette-Guerin (BCG) vaccine for melanoma</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007583 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007583">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007583</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Bacillus Calmette-Guerin (BCG), C. parvum vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4036</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4036</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus Calmette-Guerin (BCG), Corynebacterium parvum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007584 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007584">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007584</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4035</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4035</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus Calmette-Guerin (BCG), dinitrochlorobenzene (DNCB) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007585 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007585">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007585</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4034</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4034</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Bacillus Calmette-Guerin (MER) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007586 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007586">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007586</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4021</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4021</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG and chemotherapy for malignant melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007587 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007587">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007587</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4022</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4022</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG and Corynebacterium parvum for malignant melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007588 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007588">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007588</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4033</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4033</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG treatment after surgical tumor removal vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007589 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007589">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007589</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5399</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0007328"/>
        <rdfs:label>obsolete Bcl-Xs Adenovirus Vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007590 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007590">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007590</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4017</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4017</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Biolistic DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007591 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007591">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007591</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3984</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3984</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Canvaxin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007592 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007592">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007592</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5476</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0007358"/>
        <rdfs:label>obsolete CD80 Breast Cancer Vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007593 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007593">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007593</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4072</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4072</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>class I HLA-A0201-restricted gp100209-2M peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007594 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007594">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007594</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5456</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5456</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Contusugene ladenovec vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007595 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007595">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007595</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3990</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>3990</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>CpG 7909/PF3512676 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007596 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007596">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007596</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4170</obo:IAO_0000119>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
        <obo:VO_0001818>4170</obo:VO_0001818>
        <rdfs:comment>Recorded as licensed cancer vaccine without reference. Based on the vaccine name, it is not correct, see term:VO:0004719.</rdfs:comment>
        <rdfs:label>obsolete CVB4/p24(73(3)) vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007597 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007597">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007597</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5494</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5494</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>dendritic cell-Idiotype-Keyhole Limpet Hemocyanin vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007598 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007598">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007598</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5346</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11054"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5346</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>DEPDC1/MPHOSH1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007599 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007599">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007599</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5116</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5116</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>DLK1/EPHA2/HBB/NRP1/RGS5/TEM1 peptide-pulsed alpha-type-1 polarized dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007600 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007600">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007600</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4060</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>4060</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA vaccine encoding p42.3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007601 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007601">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007601</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3998</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>3998</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>DNP-modified autologous vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007602 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007602">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007602</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4076</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4076</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>electroloading of mature dendritic cells with melanoma whole tumor cell lysate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007603 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007603">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007603</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4067</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4067</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>ESAT-6-gpi DNA vaccine combined with B16F10-ESAT-6-gpi/IL-21 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007604 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007604">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007604</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4081</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>4081</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Flagrp170 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007605 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007605">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000652"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9685"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007605</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4018</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>4018</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>FVAX vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007606 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007606">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007606</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4047</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>4047</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>GM-CSF transfected cells vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007607 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007607</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4008</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>4008</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>gp100 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007608 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007608</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3974</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>3974</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>gp100:209-217(210M) peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007609 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007609</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5438</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5438</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>gp100:280-288(288V) peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007610 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007610">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007610</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5062</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>5062</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>GVAX pancreatic cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007611 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007611">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007611</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4010</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>4010</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>hapten dinitrophenyl vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007612 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007612">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007612</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3992</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>3992</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>HCA587 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007613 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007613">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007613</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4053</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4053</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>hMART-IT vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007614 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007614">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007614</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3986</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>3986</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>HSP65-HER2 fusion peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007615 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007615">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007615</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4058</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>4058</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Hsp70 chaperone-based gel composition vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007616 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007616">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007616</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3982</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3982</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>HSPPC-96 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007617 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007617">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007617</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3980</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3980</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>human leukocyte antigen class I-modified peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007618 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007618">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007618</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4077</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4077</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>HUVECs-OK432 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007619 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007619">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007619</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3976</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>3976</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>IDD-3 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007620 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007620">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007620</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4009</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>4009</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>IFN/tremem vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007621 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007621">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007621</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4062</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4062</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>IL-12p70 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007622 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007622">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007622</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3977</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>3977</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>IMM-101 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007623 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007623">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007623</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4069</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4069</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Incomplete Freund&apos;s adjuvant (IFA) alone, or a melanoma vaccine in IFA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007624 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007624">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007624</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4037</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>4037</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>intralesional bacile Calmette-Guerin (BCG) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007625 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007625">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007625</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4038</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>4038</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>intralesional bacile Calmette-Guerin (BCG), DTIC, vincristine vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007626 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007626">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007626</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3975</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3975</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>ipilimumab vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007627 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007627">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007627</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4045</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4045</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>ipilimumab, vemurafenib vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007628 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007628">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007628</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4012</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4012</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>irradiated autologous cell  vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007629 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007629">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007629</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4050</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4050</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>irradiated melanoma cells plus BCG vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007630 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007630">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007630</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5472</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5472</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>KSA-KLH conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007631 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007631">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007631</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4000</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4000</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>L612 HuMAb vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007632 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007632">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007632</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3968</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3968</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Large Multivalent Immunogen (LMI) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007633 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007633">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007633</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4048</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4048</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>long-peptide vaccine and mAb</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007634 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007634">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007634</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4066</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4066</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mAb PC61 and DC/tumor fusion vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007635 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007635">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007635</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4005</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4005</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>MAGE-A12:170-178 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007636 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007636">
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007636</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4059</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4059</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>MAGE-A3 + AS15 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007637 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007637">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007637</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4039</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4039</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>MAGE-A3-genetically modified lymphocyte vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007638 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007638">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007638</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4065</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4065</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>MCMV-TRP2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007639 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007639">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007639</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4046</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>4046</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mCRT-vGPCR-coated whole-cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007640 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007640">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007640</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Melacine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3996</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3996</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Melacine vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007641 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007641">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007641</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3985</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3985</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Melan-A/Mart-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007642 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007642">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004914"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007642</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Melanoma-specific Melan-A/Mart-1 peptide + virus-like nanoparticles</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3979</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3979</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>melanoma-specific Melan-A/Mart-1 peptide + virus-like nanoparticles vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007643 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007643">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007643</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5412</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5412</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>modified Vaccinia virus ankara vaccine expressing p53</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007644 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007644">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007644</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4068</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4068</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mouse/human gp10025-33 peptide plus CpG adjuvant; mouse/human gp100; mouse/human gp10025-33 peptide-pulsed DCs  vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007645 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007645">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005493"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007645</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5224</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>5224</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>multi-epitope folate receptor alpha-loaded dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007646 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007646</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4063</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4063</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Multipeptide melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007647 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007647">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007647</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4030</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4030</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Oral Bacille Calmette-Guerin for malignant melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007648 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007648">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007648</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3983</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>3983</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>OVA-TEXO vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007649 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007649">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007649</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4032</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>4032</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>procarbazine, dactinomycin, velba vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007650 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007650">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000422"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007650</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4031</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001818>4031</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>Pulmonary BCG immunotherapy for malignant melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007651 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007651">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007651</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6075</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>6075</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>RIPO(H3.3) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007652 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007652">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007652</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4011</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>4011</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>alpha-GalCer-loaded tumor-cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007653 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007653">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/DOID_162"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004019"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007654"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004019"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007654"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007653</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer that is caused by human papillomavirus (HPV) infection. HPV infection can lead to six types of cancer including anal, cervical, oropharyngeal, penile, vaginal, and vulvar cancer.</obo:IAO_0000115>
        <obo:IAO_0000116>placeholder, will send new term requst to DOID</obo:IAO_0000116>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/677</obo:IAO_0000233>
        <obo:RO_0004019 rdf:resource="http://purl.obolibrary.org/obo/VO_0007654"/>
        <oboInOwl:inSubset>disposition</oboInOwl:inSubset>
        <rdfs:label>HPV associated cancer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007654 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007654">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IDO_0000586"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007654</metadata:prefixIRI>
        <obo:IAO_0000115>An infection that has as part organisms of the human papillomavirus (HPV).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/677</obo:IAO_0000233>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>HPV infection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007655 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007655">
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0010332"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0010333"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_1110034"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007655</metadata:prefixIRI>
        <obo:IAO_0000115>Either a tumor-specific or a tumor-associated antigen.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/677</obo:IAO_0000233>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>tumor antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007656 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007656">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000177"/>
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        <obo:IAO_0000115>Cancer vaccine that prevents cancer formation and development.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/677</obo:IAO_0000233>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>preventive cancer vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007657 -->

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        <obo:IAO_0000115>Cancer vaccine that aims to eliminate or control tumor cells.</obo:IAO_0000115>
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        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
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        <rdfs:label>therapeutic cancer vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007658 -->

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        <obo:IAO_0000115>A cancer vaccine that uses whole cells to deliver cancer antigen(s).</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>whole cell cancer vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007659 -->

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        <obo:IAO_0000115>A whole cell cancer vaccine that uses whole tumor cells to deliver cancer antigen(s).</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:37355722</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/683</obo:IAO_0000233>
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        <rdfs:label>whole tumor cell cancer vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007660 -->

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        <obo:IAO_0000115>A cancer vaccine that is composed of a plasmid vaccine vector (a circular double stranded DNA molecule) containing the whole of parts of genes encoding one or more vaccine antigen proteins.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>DNA cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007661 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007661</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with T cells  genetically engineered to express anti-GD2 Chimeric Antigen Receptor to treat patients with children and young adults with GD2+ solid tumors, including neuroblastoma. The T cells may have an antitumor effect. They can be used in combination with AP1903 and Cyclophosphamide. (NCT02107963) There are increased CXCR3- classical monocytes in patients as CAR-T numbers waned.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02107963</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:38134936</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6381</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6381</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>GD2-CAR vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007662 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007662</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine used to treat patients with small cell lung cancer by using several components (small cell lung cancer targets) that have been tested individually in patients with small cell lung cancer or other cancers (GD2, GD3, Globo H, Fucosyl GM1 and N-propionylated polysialic acid) so that the body will make antibodies to the vaccine which will also react against the cancer. Two other substances (KLH and OPT-821) are added which boost the immune system. Vaccination with the pentavalent KLH conjugate vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing any of these antigens.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C97034</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01349647</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6275</obo:IAO_0000119>
        <obo:OGG_0000000006>2524</obo:OGG_0000000006>
        <obo:OGG_0000000006>2583</obo:OGG_0000000006>
        <obo:OGG_0000000006>6489</obo:OGG_0000000006>
        <obo:OGG_0000000006>8705</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6275</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GD 2</rdfs:comment>
        <rdfs:comment>Gene name: GD3</rdfs:comment>
        <rdfs:comment>Gene name: Globo H</rdfs:comment>
        <rdfs:comment>Gene name: fucosyl GM1</rdfs:comment>
        <rdfs:label>GD2L, GD3L, Globo H, fucosyl GM1, and N-propionylated polysialic acid KLH conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007663 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007663</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with HLA class I-matched allogeneic human prostate carcinoma cells that are genetically engineered to secrete interleukin-2 and interferon gamma for patients with prostate carcinoma. Interleukin-2 may stimulate a person&apos;s white blood cells including natural killer cells to kill prostate cancer cells. Interferon gamma may interfere with the growth of the cancer cells. Combining interferon gamma with interleukin-2 may be a more effective treatment for prostate cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>genetically engineered allogeneic prostate carinoma cells secreting interleukin-2 and interferon gamma</obo:IAO_0000118>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00002637</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6292</obo:IAO_0000119>
        <obo:OGG_0000000006>3458</obo:OGG_0000000006>
        <obo:OGG_0000000006>3558</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6292</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IL2</rdfs:comment>
        <rdfs:comment>Gene name: Interferon gamma</rdfs:comment>
        <rdfs:label>genetically engineered allogeneic prostate carinoma cells secreting interleukin-3 and interferon gamma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007664 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007664</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of K562 cells transfected with the granulocyte macrophage-colony stimulating factor (GM-CSF) gene with potential immunopotentiating properties. This vaccine may stimulate the host immune system to produce an antitumoral T-lymphocyte response, thereby inhibiting tumor growth. A cultured cell line is genetically changed to secrete GM-CSF mixed with irradiated leukemia cells obtained from a patient. Vaccines made from gene-modified cancer cells may help the body build an effective immune response to kill cancer cells. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving vaccine therapy together with imatinib mesylate may be an effective treatment for chronic myelogenous leukemia. The vaccine can also be combined with stem cell transplantation. The vaccine may induce an immune response to common myeloid antigens (e.g., Wilms&apos; tumor-1 [WT-1], survivin, or proteinase-3) in patients with Myelodysplastic Syndrome. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C52190</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00301093</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00361296</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00442130</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00809250</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6293</obo:IAO_0000119>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6293</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:label>GM-K562 cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007665 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007665</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of irradiated tumor cells transduced with granulocyte-macrophage colony-stimulating factor (GM-CSF) and CD40-ligand (CD40L) genes. The vaccine may stimulate an anti-tumoral dendritic cell-mediated host immune response. Universal GM-CSF-producing and CD40L-expressing bystander cell line is used to form an autologous tumor cell-based vaccine for patients with mantle cell lymphoma in order to make the body build an effective immune response to kill cancer cells. It can be used in combination with Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, Dexamethasone, and IL-2. The vaccine can be done with bystander and autologous tumor cells for patients with malignant melanoma. It can also be combined with lenalidomide for patients with myelodysplastic syndrome (MDS).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119> NCT: https://clinicaltrials.gov/study/NCT00840931</obo:IAO_0000119>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C48391</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00101101</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00101166</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6271</obo:IAO_0000119>
        <obo:OGG_0000000006>959</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6271</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40LG</rdfs:comment>
        <rdfs:label>GM.CD40L cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007666 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007666</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine using dendritic cells (a kind of white blood cell) as a vaccine could stimulate your own immune system to react to your melanoma cells. Autologous dendritic cells are pulsed with 2 gp100 melanoma peptides (G209-2M and G280-9V) plus up to an additional 10 unique melanoma tumor-specific peptides. Patients also receive cyclophosphamide 300mg/m2 IV in order to deplete regulatory T cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00683670</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6308</obo:IAO_0000119>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6308</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>gp100 mature dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007667 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007667</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that uses irradiated, adenovirus transduced autologous myeloblasts to secrete granulocyte-macrophage colony-stimulating factor (GVAX) early after allogeneic hematopoietic stem cell transplantation (HSCT) to induce potent immune responses. The vaccine may prevent advanced myelodysplastic syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), or acute myeloid leukemia (AML) from relapsing after stem cell transplant. The patients own cancer cells are engineered to produce a protein called GM-CSF, which can be effective in stimulating a powerful immune response specific to that cancer. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01773395</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:34807983</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6385</obo:IAO_0000119>
        <obo:OGG_0000000006>1437</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6385</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: GM-CSF</rdfs:comment>
        <rdfs:label>GVAX leukemia vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007668 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007668">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007668</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of a peptide derived from histone H3.3 containing the amino acid substitution mutation lysine (Lys) 27-to-methionine (H3.3K27M), with potential immunoactivating and antineoplastic activities. Following the administration of the vaccine, the immune system may exert a cytotoxic T-lymphocyte (CTL)-mediated immune response against H3.3K27M-expressing tumor cells. A lysine 27-to-methionine (K27M) somatic mutation at histone H3 variant (H3.3) is a feature mutation in diffuse intrinsic pontine gliomas (DIPGs). This vaccine contains an H3.3-K27M targeted neoantigen peptide that can be taken up by antigen-presenting cells (APCs). APCs can present the peptide with the major histocompatibility complex (MHC) molecules on cell surface, thereby activating neoantigen-specific T cells and triggering corresponding cytotoxic T cell immune responses to eliminate H3.3-K27M-expressing DIPG cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C132684</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04749641</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6295</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6295</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>H3.3K27M-specific peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007669 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007669">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007669</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of HER-2-neu and carcinoembryonic antigen synthetic (CEA) peptides, combined with the adjuvants granulocyte-macrophage colony stimulating factor (GM-CSF), and Montanide ISA-51 with potential antineoplastic activity. The vaccine may stimulate a cytotoxic T-cell response against HER-2-neu- and CEA-expressing tumor cells. Vaccines made from peptides may make the body build an immune response to kill tumor cells. This vaccine is compromised of HER-2-neu and carcinoembryonic antigen synthetic peptides, sargramostim (GM-CSF), and Montanide ISA-51, and aims to cause an immune response in patients with stage IIB, III, or IV colorectal cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C48392</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00091286</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6294</obo:IAO_0000119>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
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        <obo:VO_0001818>6294</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HER-2-neu</rdfs:comment>
        <rdfs:comment>Gene name: carcinoembryonic antigen</rdfs:comment>
        <rdfs:label>HER-2-neu, CEA peptides, GM-CSF, montanide ISA-51 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007670 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007670">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007670</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made from peptides that may help the body build an effective immune response to kill tumor cells. Patients with HER2 positive locally advanced breast cancer can be vaccinated with a HER2 Intracellular Domain (ICD) peptide-based vaccine administered concurrently with trastuzumab. The vaccine may lead to an immune response (HER2 specific T cell immunity and/or the development of intramolecular epitope spreading).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00343109</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6352</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6352</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HER-2/neu</rdfs:comment>
        <rdfs:label>HER2 ICD peptide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007671 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007671</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine for vaccination with neoantigens that can both expand pre-existing neoantigen-specific T-cell populations and induce a broader repertoire of new T-cell specificities in cancer patients, tipping the intra-tumoural balance in favour of enhanced tumour control. The vaccine targets up to 20 predicted personal tumour neoantigens. The vaccine induced CD4+ and CD8+ T cells responses. These T cells discriminated mutated from wild-type antigens, and in some cases directly recognized autologous tumour.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:28678778</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6377</obo:IAO_0000119>
        <obo:OGG_0000000006>3123</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6377</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HLA</rdfs:comment>
        <rdfs:label>HLA neoantigen vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007672 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007672</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made from a person&apos;s white blood cells mixed with tumor proteins (HLA-A1- and HLA-A2.1-restricted peptides derived from melanoma-associated tumor antigens) and CD40-ligand, and may make the body build an immune response to kill tumor cells. This is combined with denileukin diftitox, which </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00056134</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6283</obo:IAO_0000119>
        <obo:OGG_0000000006>3105</obo:OGG_0000000006>
        <obo:OGG_0000000006>959</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6283</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CD40L</rdfs:comment>
        <rdfs:comment>Gene name: HLA-A</rdfs:comment>
        <rdfs:label>HLA-A1, HLA-A2, and CD40-ligand pulsed dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007673 -->

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        <obo:IAO_0000115>A cancer vaccine consisting of Hodgkin lymphoma cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Hodgkin antigens-GM-CSF-expressing cell vaccine may stimulate a cytotoxic T-lymphocyte (CTL) immune response against Hodgkin lymphoma-associated antigens, which may result in the lysis of tumor cells expressing these antigens. Also, transfected Hodgkin lymphoma cells secrete GM-CSF, which may potentiate the CTL response against Hodgkin lymphoma-associated antigens. Vaccines made from a tumor antigen may help the body build an effective immune response to kill tumor cells. This vaccine contains cells expressing Hodgkin&apos;s antigens and GM-CSF, and could cause an immunological response in Hodgkin&apos;s lymphoma patients.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C61592</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00478062</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6296</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6296</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>hodgkin&apos;s antigens-GM-CSF-expressing cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007674 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007674</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a recombinant, attenuated, replication-incompetent form of the Semliki Forest Virus (SFV) vector encoding the viral oncoproteins E6 and E7 derived from the human papillomavirus (HPV), with potential immunomodulating and antineoplastic activities. The vaccine induces expression of the E6/E7 proteins and stimulates both the innate and the adaptive immune system, resulting in a potent cytotoxic T-lymphocyte (CTL) response against and lysis of tumor cells expressing HPV E6 and E7. The vaccine may help to treat patients with a history of (pre) malignant cervical lesions.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C148539</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03141463</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6369</obo:IAO_0000119>
        <obo:OGG_0000000006>1489078</obo:OGG_0000000006>
        <obo:OGG_0000000006>1489079</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6369</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: E6</rdfs:comment>
        <rdfs:comment>Gene name: E7</rdfs:comment>
        <rdfs:label>HPV E6/E7-encoding semliki forest virus vaccine Vvax001</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007675 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007675</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of irradiated allogeneic breast cancer cell lines (HAB-1 and HAB-2) that have been transduced with a recombinant Moloney murine leukemia virus (MoMLV)-based retroviral vector expressing the murine alpha (1,3) GT gene. The immune response to the foreign substance could stimulate the immune system to attack the patient&apos;s own cancer cells that have similar proteins without this sugar pattern, causing the tumor to remain stable or shrink.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00090480</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6297</obo:IAO_0000119>
        <obo:OGG_0000000006>14594</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
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        <obo:VO_0001818>6297</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Ggta1</rdfs:comment>
        <rdfs:label>hyperacute - breast cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007676 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007676</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of irradiated allogeneic melanoma cell lines (HAM-1, HAM-2 and HAM-3). These cell lines have been transduced with a recombinant Moloney murine leukemia virus (MoMLV)-based retroviral vector expressing the murine alpha(1,3)GT gene, a mouse gene that causes the production of a foreign pattern of protein-sugars on the cell surface. The immune response to the foreign substance could stimulate the immune system to attack the patient&apos;s own cancer cells that have similar proteins without this sugar pattern, causing the tumor to remain stable or shrink.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00300612</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6298</obo:IAO_0000119>
        <obo:OGG_0000000006>14594</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6298</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Ggta1</rdfs:comment>
        <rdfs:label>hyperacute-melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007677 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007677</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of irradiated allogeneic prostate cancer cell lines (HAP-1 and HAP-2) that have been transduced with a recombinant Moloney murine leukemia virus (MoMLV)-based retroviral vector expressing the murine alpha (1,3) GT gene, a mouse gene that causes the production of a foreign pattern of protein-sugars on the cell surface. It is hoped that the immune response to the foreign substance will stimulate the immune system to attack the patient&apos;s own cancer cells that have similar proteins without this sugar pattern, causing the tumor to remain stable or shrink.. The expression of the murine alpha (1,3) galactosyltransferase [alpha (1,3) GT] gene results in the cell surface expression of alpha (1,3) galactosyl-epitopes (alpha-gal) on membrane glycoproteins and glycolipids.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00105053</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6299</obo:IAO_0000119>
        <obo:OGG_0000000006>14594</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6299</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Ggta1</rdfs:comment>
        <rdfs:label>hyperacute-prostate cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007678 -->

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            </owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007678</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine derived from the immunomodulatory enzyme indoleamine 2,3-dioxygenase (IDO) with potential immunomodulating and antineoplastic activities. It may activate the immune system to induce an immune response against IDO-expressing tumor cells, which may restore the proliferation and activation of various immune cells including cytotoxic T-lymphocytes (CTLs), natural killer cells (NKs), and dendritic cells (DCs), and may eradicate IDO-expressing tumor cells through a CTL-mediated response. This vaccine, using a small fragment of IDO, can be used in combination with either Ipilimumab or Vemurafenib to treat malignant melanoma that has metastasized. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C159498</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02077114</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6368</obo:IAO_0000119>
        <obo:OGG_0000000006>3620</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6368</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IDO</rdfs:comment>
        <rdfs:label>IDO peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007679 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007679</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine compromised of melanoma peptides plus GM-CSF-in-adjuvant. It is combined with low-dose IL-2 therapy, which could significantly enhance the immunologic efficacy.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00928902</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6312</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6312</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>IL-2 peptide and GM-CSF-in-adjuvant melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007680 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007680">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007680</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with autologous dendritic cells that are manufactured with GM-CSF, IL15 and loaded with melanoma/HIV peptides and KLH; then activated with LPS and CD40 Ligand.IL15 is a T cell growth factor that could have a very important role in cancer immunotherapy. IL15 DCs are particularly efficient at priming functional melanoma specific CD8+ T cells. The use of IL15 in the manufacture of the DC vaccine could result in an improved immunotherapy product for melanoma patients.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01189383</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6300</obo:IAO_0000119>
        <obo:OGG_0000000006>3600</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
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        <obo:VO_0001818>6300</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IL15</rdfs:comment>
        <rdfs:label>IL15-DC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007681 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007681">
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        <obo:IAO_0000115>A cancer vaccine that could teach T-cells to detect and kill cancer cells better. Intracel KLH is given without adjuvant subcutaneously and with Tetanus Toxoid 0.5 ml intramuscularly.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00000105</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6302</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001818>6302</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>intracel KLH vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007682 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007682</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with dendritic cells pulsed with KLH and tumor lysate for patients with neuroblastoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02745756</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6303</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6303</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>KLH and tumor lysate pulsed DC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007683 -->

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        <obo:IAO_0000115>A cancer vaccine made of tumor protein taken from a cancer patient&apos;s plasma (liquid part of the blood) and KLH (a protein designed to increase the immune response of the vaccine).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01174082</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6259</obo:IAO_0000119>
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        <obo:VO_0001818>6259</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>KLH-id vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007684 -->

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        <obo:IAO_0000115>A cancer vaccine made with autologous dendritic cells  pulsed with KLH for this vaccination, combined with radiation or a gene therapy agent, TNFerade. TNFerade or radiation serves to generate cell death stimulating the immune response. The dendritic cell vaccine may direct a distant and lasting effective anti-tumor immune response to achieve a local and systemic clinical benefit.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00868114</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6304</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6304</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>KLH-pulsed autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007685 -->

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        <obo:IAO_0000115>A cancer vaccine used alone or in combination with PD-1 inhibitor in patients with advanced solid tumors with KRAS mutation (G12C, G12D, or G12V) and HLA type HLA-A11:01 or HLA C08:02. The vaccine is a lipid nanoparticle (LNP)-formulated mRNA-based cancer vaccine that targets the most commonly occurring KRAS mutations (G12D, G12V, and G12C). The mRNA-derived KRAS-targeted vaccine V941 (mRNA-5671) is taken up and translated by antigen presenting cells (APCs). Following translation, the epitopes are presented via major histocompatibility complex (MHC) molecules on the surface of the APCs. This leads to an induction of both cytotoxic T-lymphocyte (CTL)- and memory T-cell-dependent immune responses that specifically target and destroy tumor cells harboring these specific KRAS mutations.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C162186</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05202561</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6348</obo:IAO_0000119>
        <obo:OGG_0000000006>3845</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6348</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: KRAS</rdfs:comment>
        <rdfs:label>KRAS-targeted mRNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007686 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007686</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with Epstein Barr Virus (EBV)-derived tumor antigen, Latent Membrane Protein-2 (LMP2)-loaded dendritic cell (DC) vaccines are administered alone or co-administered with the TLR9 ligand, DUK-CPG-001, in patients with EBV+ lymphoma in the setting of autologous stem cell transplant with infusion of mature T cells. It may induce EBV derived tumor antigen specific CD8+ T cell response in patients with EBV+ lymphoma in the setting of autologous stem cell transplant.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02115126</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6305</obo:IAO_0000119>
        <obo:OGG_0000000006>10376</obo:OGG_0000000006>
        <obo:OGG_0000000006>5698</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6305</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EBV</rdfs:comment>
        <rdfs:comment>Gene name: LMP2</rdfs:comment>
        <rdfs:label>LMP2A-loaded conventional DC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007687 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007687</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of multiple peptides derived from MAGE-1A, Her-2/neu, and folate binding protein (FBP), with potential immunostimulating and antineoplastic properties. The MAGE-A1, Her-2/neu, FBP peptides cancer vaccine includes the peptides MAGE-A1:161-169, FBP:191-199, Her-2/neu:369-377, MAGE-A1:96-104, and Her-2/neu:754-762. Vaccination with this cancer vaccine may activate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing the corresponding antigens, resulting in tumor cell lysis. The vaccine compromises synthetic ovarian cancer-associated peptides administered with a synthetic tetanus toxoid helper peptide emulsified in Montanide ISA-51 before or after paclitaxel and carboplatin in patients with stage III-IV ovarian epithelial, primary peritoneal cavity, or fallopian tube cancer undergoing optimal cytoreductive surgery. Vaccines made from peptides may help the body build an effective immune response to kill tumor cells. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving vaccine therapy and chemotherapy after surgery may kill any tumor cells that remain after surgery.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C62775</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00373217</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6306</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:OGG_0000000006>2348</obo:OGG_0000000006>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6306</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: FBP</rdfs:comment>
        <rdfs:comment>Gene name: HER2-neu</rdfs:comment>
        <rdfs:comment>Gene name: MAGE-A1</rdfs:comment>
        <rdfs:label>MAGE-A1, Her-2/neu, FBP peptides ovarian cancer vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007688 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007688</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with autologous dendritic cells (DC) are transduced with the MART-1, tyrosinase and MAGE-A6 (melanoma associated antigens, MAA) genes for melanoma patients. Some patients also receive interferon-alfa 2b (IFN) intravenously.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01622933</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6280</obo:IAO_0000119>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>4105</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
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        <obo:VO_0001818>6280</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGE-A6</rdfs:comment>
        <rdfs:comment>Gene name: MART-1</rdfs:comment>
        <rdfs:comment>Gene name: tyrosinase</rdfs:comment>
        <rdfs:label>MART-1, tyrosinase and MAGE-A6 autologous DC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007689 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007689</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that may elicit a cytotoxic T-cell (CTL) response against cancer cells. Autologous dendritic cells are pulsed with melanoma tumor-specific peptides. The mature dendritic cell (mDC3/8) vaccine (primer and booster) in patients with stage III and stage IV melanoma is followed by treatment with pembrolizumab (anti-PD-1 therapy). Using dendritic cells (a kind of white blood cell) as a vaccine could stimulate your own immune system to react to your melanoma cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C162250</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03092453</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6307</obo:IAO_0000119>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6307</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mature dendritic cell melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007690 -->

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        <obo:IAO_0000115>A cancer vaccine made up of two peptides that are pieces of a bigger melanoma protein (gp100). These peptides bind to HLA-A2 which is then recognized by T cells. It could be given in combination with MDX-010 (ipilimumab, BMS-734016). MDX-010 (anti-CTLA4) antibodies are designed to keep the immune system running by blocking CTLA-4 from down-regulating T cell activation.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00094653</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6309</obo:IAO_0000119>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
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        <obo:VO_0001818>6309</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:label>MDX-1379 (gp100) melanoma peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007691 -->

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        <obo:IAO_0000115>A cancer vaccine composed of CTLA-4 antibody; tyrosinase, gp100, and MART-1 peptides; and incomplete Freund&apos;s adjuvant (IFA) with or without interleukin-12 in patients with resected stage III or IV melanoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00028431</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6310</obo:IAO_0000119>
        <obo:OGG_0000000006>2315</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
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        <obo:VO_0001818>6310</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MART-1</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:comment>Gene name: tyrosinase</rdfs:comment>
        <rdfs:label>MDX-CTLA4 antibody/tyrosinase/gp100/MART-1 melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007692 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007692</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of peptides derived from melanoma-associated antigens and an adjuvant peptide derived from tetanus toxoid. Vaccination with this agent may stimulate a host cytotoxic T-cell response against tumor cells expressing melanoma-associated antigens, resulting in tumor cell lysis. Vaccines made from peptides may make the body build an immune response to kill tumor cells. Vaccines using melanoma peptides from cytotoxic T cells and helper T cells could work in treating patients with metastatic melanoma. This vaccine contains 12 melanoma peptides restricted by Human Leukocyte Antigen (HLA)-A1, -A2, or -A3 and 6 melanoma helper peptides restricted by HLA-DR molecules emulsified with sargramostim (Granulocyte-macrophage colony-stimulating factor, GM-CSF) and Montanide ISA-51 or Montanide ISA-51 VG (ISA-51).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C38700</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/ct2/show/NCT00071981</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6311</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6311</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>melanoma helper peptide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007693 -->

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        <obo:IAO_0000115>A cancer vaccine containing a mixture of killed bacteria with potential immunostimulatory and antineoplastic activities. Mixed bacteria vaccine (MBV or Coley&apos;s toxins) consists of a pyrogenic bacterial lysate derived from Serratia marcescens and Streptococcus pyogenes; the active components in the lysate may be lipopolysaccharide (LPS), a component of the Gram-negative bacterial cell wall of Serratia, and streptokinase, an enzyme produced by Streptococcus pyogenes. LPS has been shown to stimulate the host humoral immune response and induce the release of various antitumor cytokines such as tumor necrosis factor (TNF) and interleukin-12 (IL-12). The mixed bacteria vaccine (MBV) is administered at a starting dose of 250 EU (1 µL) and escalated in each patient to a dose inducing the desired pyrogenic effect, defined as a body temperature of 38°C to 39.5°C. It is given to patients with malignant tumors that expressed the NY-ESO-1 antigen. It is designed to induce immunological effects and tumor response following vaccination. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C74063</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00623831</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6314</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6314</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mixed bacterial cancer vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007694 -->

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        <obo:IAO_0000115>A cancer vaccine with or without PD-1/L1 may help treat patients with advanced gastric cancer. A personalized mRNA tumor vaccine encoding neoantigen may also help treat patients with advanced esophageal squamous carcinoma, gastric adenocarcinoma, pancreatic adenocarcinoma and colorectal adenocarcinoma. The vaccine can also be used in combination with PD-1 for the treatment of advanced solid tumors.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03468244</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05227378</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05359354</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6328</obo:IAO_0000119>
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        <obo:VO_0001818>6328</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mRNA neoantigen tumor vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007695 -->

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        <obo:IAO_0000115>A cancer vaccine made with dendritic cells (DCs) pulsed with mRNA encoded tumor antigens. These personalized cell vaccines may lead to antitumor specific T cell responses. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02808416</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6339</obo:IAO_0000119>
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        <obo:VO_0001818>6339</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mRNA tumor antigen DC vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007696 -->

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        <obo:IAO_0000115>A cancer vaccine targeting up to fifteen tumor-associated antigens (TAAs) that are specifically expressed by a patient&apos;s cancer cells, with potential immunostimulatory and antineoplastic activities. Up to fifteen neoantigen epitopes are incorporated in a proprietary formulation designed to maximize mRNA delivery and minimize mRNA-triggered immune responses. The mRNA-based PCV NCI-4650 is taken up and the mRNAs are translated by antigen presenting cells (APCs). Then, the expressed epitopes are presented via major histocompatibility complex (MHC) molecules on the surface of the APCs. This induces both cytotoxic T-lymphocyte (CTL)- and memory T-cell-dependent immune responses that specifically target and destroy the patient&apos;s cancer cells that express these neoantigens. Exome sequencing can identify certain gene mutations in a person&apos;s tumor. This can then be used to create cancer treatments. This mRNA vaccine might cause certain tumors to shrink. Immunogenic neoantigens and can predict for neoantigens binding the patient human leukocyte antigen (HLA) molecules from melanoma or epithelial cancer patients and use these epitopes for a personalized therapeutic messenger ribonucleic acid (mRNA) vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C148239</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03480152</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6324</obo:IAO_0000119>
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        <obo:VO_0001818>6324</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>mRNA-based personalized cancer vaccine NCI-4650</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007697 -->

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        <obo:IAO_0000115>A cancer vaccine consisting of autologous monocytes loaded with mRNA encoding the human cytomegalovirus (CMV) matrix protein pp65 (65 kDa lower matrix phosphoprotein; UL83) as a fusion protein with the lysosome-associated membrane protein (LAMP), with potential immunostimulatory and antineoplastic activities. The autologous CMV-pp65-LAMP mRNA loaded monocyte vaccine MT-201-GBM exposes the immune system to the CMV pp65 peptide, which may elicit a cytotoxic T-lymphocyte (CTL) response against CMV pp65-expressing tumor cells. The incorporation of LAMP may route CMV pp-65 antigens into the lysosomal compartment, resulting in enhanced MHC class II antigen presentation, thereby promoting CD4-positive T-cell responses. MT-201-GBM (pp65CMV antigen monocytes) are administered to patients newly diagnosed with a type of brain tumor called glioblastoma (GBM) that has an unmethylated MGMT (O[6]-methylguanine-DNA methyltransferase) (MGMT) gene promoter. The vaccine is made from a type of immune cell called monocytes, which have been engineered to express a cytomegalovirus (CMV) protein. Patients also receive standard radiation therapy combined with temozolomide.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C179670</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04741984</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6315</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6315</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>MT-201-GBM monocyte vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007698 -->

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        <obo:IAO_0000115>A cancer vaccine containing mucus 1 (MUC1) peptide and the adjuvant poly-ICLC with potential immunostimulatory and antineoplastic activities. MUC1 peptide-poly-ICLC adjuvant vaccine may induce the host immune system to mount a cytotoxic T cell response against MUC1-expressing tumor cells. MUC1 peptide-poly-ICLC adjuvant vaccine in boosting systemic immunity to MUC1 in women with stage I-III &apos;triple-negative&apos; [i.e., ER(-) PR(-) HER2/neu(-)] breast cancer. MUC1 peptide-Poly-ICLC vaccine could also work in preventing lung cancer in current and former smokers at high risk for lung cancer. Vaccines made from peptides may help the body build an effective immune response to kill cells. MUC1 peptide-Poly-ICLC vaccine may stimulate the body&apos;s immune system and slow or stop the changes from normal to pre-cancer to cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C82417</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00986609</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03300817</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6316</obo:IAO_0000119>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
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        <obo:VO_0001818>6316</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MUC-1</rdfs:comment>
        <rdfs:label>MUC1 peptide-poly-ICLC vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007699 -->

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        <obo:IAO_0000115>A cancer vaccine comprised of four peptides derived from the tumor-associated antigen (TAA) HER-2/neu (ErbB-2), with potential immunomodulating and antineoplastic activities. The four peptides may induce a cytotoxic T-lymphocyte (CTL)-mediated immune response against tumor cells expressing the HER-2/neu antigen, which may result in the inhibition of proliferation in Her-2/neu-expressing tumor cells. TPIV100 is a type of vaccine made from HER2 peptide that may help the body build an effective immune response to kill tumor cells that express HER2. Sargramostim increases the number of white blood cells in the body following chemotherapy for certain types of cancer and is used to alert the immune system. TPIV100 and sargramostim could work in treating patients with HER2 positive, stage II-III breast cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C173525</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04197687</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6317</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6317</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HER2</rdfs:comment>
        <rdfs:label>multi-epitope HER2 peptide vaccine TPIV100</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007700 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007700</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a combination of peptides derived form several melanoma epitopes. Vaccination with multi-epitope melanoma peptide vaccine stimulates the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the corresponding antigens, resulting in tumor cell lysis. This vaccine may stimulate a broader CTL response compared to single-antigen vaccines. Vaccines made from melanoma peptides or antigens may help the body build an effective immune response to kill tumor cells in patients with stage IIC-IV melanoma. This vaccine is a tyrosinase/gp100/MAGE-3 class I peptide vaccine combined with Montanide ISA 51 or ISA 51 VG with CpG adjuvant 7909 in human leukocyte antigen (HLA) class I A1, A3 or A11 and B44 matched patients with surgically resected stages IIC, III and IV melanoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C38695</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00085189</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6318</obo:IAO_0000119>
        <obo:OGG_0000000006>3105</obo:OGG_0000000006>
        <obo:OGG_0000000006>3106</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:OGG_0000000006>6490</obo:OGG_0000000006>
        <obo:OGG_0000000006>7299</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6318</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HLA-A</rdfs:comment>
        <rdfs:comment>Gene name: HLA-B</rdfs:comment>
        <rdfs:comment>Gene name: MAGE-A3</rdfs:comment>
        <rdfs:comment>Gene name: gp100</rdfs:comment>
        <rdfs:comment>Gene name: tyrosinase</rdfs:comment>
        <rdfs:label>multi-epitope melanoma peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007701 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007701</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine for which Advanced Renal Cell Carcinoma patients undergo total nephrectomy to harvest primary tumor for vaccine preparation. Dendritic cells are then pulsed with multiantigens or tumor cells. Some patients also receive vaccination with irradiated autologous tumor lysate. The vaccine may make the body build an immune response to kill tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00004880</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6284</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6284</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>multiantigen liposome loaded dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007702 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007702">
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007702</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine adjuvant and synthetic Toll-like receptor (TLR) type 1 and 2 ligand composed of a lipopeptide containing a water-soluble derivative of Pam3-Cys, the biologically active component of the mycobacterial 19 kDa lipoprotein of mycobacteria, that is covalently linked to a synthetic peptide (GDPKHPKSF), with potential immunostimulating activity. TLR1/2 agonist Pam3Cys-GDPKHPKSF targets, binds to and activates TLR1/2, which induces CD8- and T-helper 1 CD4-positive T-cell responses. This may enhance T-cell-mediated immune responses when administered together with peptide vaccine. A multi-peptide vaccine can be used in combination with the TLR1/2 ligand XS15 in CLL patients undergoing ibrutinib-based regimes. Applying several CLL-associated antigens simultaneously increases the likelihood that a multi-clonal, broad and at the same time highly specific T-cell response is mounted, thereby preventing potential tumor escape mechanisms. The novel TLR1/2 ligand (XS15, developed in Tübingen) that (i) is water-soluble and (ii) GMP-amenable, (iii) non-toxic and (iv) effective in inducing T cells specific for peptides in vivo. A personalized multi-peptide vaccination can also be used in combination with the TLR1/2 ligand XS15 for individual patients with advanced solid and hematological malignancies without any approved treatment options. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C179595</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04688385</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05014607</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6319</obo:IAO_0000119>
        <obo:OGG_0000000006>7096</obo:OGG_0000000006>
        <obo:OGG_0000000006>7097</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6319</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TLR1</rdfs:comment>
        <rdfs:comment>Gene name: TLR2</rdfs:comment>
        <rdfs:label>multipeptide XS15 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007703 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007703</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that can efficiently present T cells with antigens of HCC sensitize their antitumor properties meanwhile low dose cyclophosphamide (CY) can effectively improve the microenvironment of immunity. Multiple signals loaded dendritic cells vaccine combined low dose of cyclophosphamide combining with radical surgery or TACE or targeted agents for patients with hepatocellular carcinoma coul prolong their survival time.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04317248</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6320</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000416"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_684"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6320</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>multiple signals loaded dendritic cells vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007704 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007704">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000577"/>
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            </owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007704</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine with neopeptides designed with single amino acid mutations to enhance their immunogenicity and bind to HLA class I and II molecules. Exome and RNA sequencing as well as in silico HLA-binding predictions to autologous HLA molecules were used to identify candidate neopeptides. Subsequently, in silico HLA-anchor placements were used to deduce putative T-cell receptor (TCR) contacts of peptides. Single amino acids of TCR contacting residues were then mutated by amino acid replacements. TIL-derived CD4+ T-cell clones showed strong responses and tumor cell lysis not only against the designed neopeptide but also against the unmutated natural peptides of the tumor. Turning tumor self-peptides into foreign antigens by introduction of designed mutations is a promising strategy to induce strong intratumoral CD4+ T-cell responses in a cold tumor like glioblastoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:36228153</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6383</obo:IAO_0000119>
        <obo:OGG_0000000006>3123</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6383</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HLA</rdfs:comment>
        <rdfs:label>mutated neopeptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007705 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007705">
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007705</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of a proprietary version of the recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding both the two human tumor-associated antigens (TAAs) carcinoembryonic antigen (CEA) and mucin-1 (MUC-1), and TRICOM, which is comprised of the three human immune-enhancing co-stimulatory molecules B7-1, ICAM-1 and LFA-3, with potential immunostimulatory and antineoplastic activities. MVA-BN-CV301, followed by multiple boosting doses of the fowlpox virus (FPV) vaccine CV301 may lead to a cytotoxic T-lymphocyte (CTL) response against CEA- and MUC-1-expressing tumor cells is activated. In addition, the CV301-dependent anti-tumor CTL response upregulates the expression of programmed cell death ligand 1 (PD-L1); therefore, when CV301 is combined with a programmed cell death 1 (PD-1) immune checkpoint inhibitor, the antitumor effect may be increased. CV301 is a poxviral-based vaccine comprised of recombinant Modified vaccinia Ankara (MVA-BN-CV301, prime) and recombinant fowlpox (FPV-CV301, boost). CV301 contains transgenes encoding two (2) tumor-associated antigens (TAA), mucin 1 (MUC1) and carcinoembryonic antigen (CEA), as well as three costimulatory molecules (B7.1, intercellular adhesion molecule 1 (ICAM-1) and lymphocyte function-associated antigen 3 (LFA-3), designated TRICOM). It is given in combination with SX-682 and M7824 for patients with Triple Negative Breast Cancer (TNBC) and Human papilloma virus (HPV) negative head and neck squamous cell carcinoma (HNSCC).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C143059</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04574583</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6321</obo:IAO_0000119>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:OGG_0000000006>3383</obo:OGG_0000000006>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:OGG_0000000006>941</obo:OGG_0000000006>
        <obo:OGG_0000000006>965</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6321</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: B7.1</rdfs:comment>
        <rdfs:comment>Gene name: CEA</rdfs:comment>
        <rdfs:comment>Gene name: ICAM-1</rdfs:comment>
        <rdfs:comment>Gene name: LFA-3</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:label>MVA-BN-CV301 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007706 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007706</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine of a chimeric peptide immunogen of human epidermal growth factor-2 (HER-2) with antineoplastic property. MVF-HER-2(628-647)-CRL 1005 vaccine, coated with poloxamer CRL-1005 to form microparticles, consists of a mutated HER-2 B-cell epitope, HER-2(628-647), and a promiscuous T cell epitope (amino acid sequence 288-302) of the measles virus fusion protein (MVF). The vaccine may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against tumor cells that overexpress the HER2 protein, resulting in tumor cell lysis. MVF-HER-2(628-647)-CRL 1005 vaccine may induce anti-HER-2 antibody in patients with metastatic or recurrent cancer (Breast, Ovarian, Non-small cell lung cancer, Gastric adenocarcinoma).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C2637</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00017537</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6322</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
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        <obo:VO_0001818>6322</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HER2</rdfs:comment>
        <rdfs:label>MVF-HER-2(628-647)-CRL 1005 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007707 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007707</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of patient-specific mutated peptide epitopes, which are immunogenic and unique to the patient&apos;s tumor, with potential immunomodulating and antineoplastic activities. The neoantigen-based anti-cancer vaccine NEO-PV-01 stimulates the host immune system to mount a specific and potent cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the neoantigens, which results in tumor cell lysis. Both metastatic squamous non-small cell lung cancer (NSCLC) and extensive stage small cell lung cancer (SCLC) are incurable with current therapies, but due to mutations induced by cigarette smoke, typically express a large number of altered proteins that can be recognized as foreign by the immune system. Targeting the immune system against tumor specific antigens using a peptide vaccine could lead to improved response rate and prolonged overall survival with no additional toxicity when combined with Pembrolizumab (monoclonal antibodies that block PD-1/PD-L1 interactions) and standard of care chemotherapy.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C129935</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03166254</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6325</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1324"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6325</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>NEO-PV-01 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007708 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007708</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that may enhance anti-tumor immune response in Renal Cell Carcinoma in combination with checkpoint inhibitors ipilimumab (anti-CTLA-4 antibody) and nivolumab (anti-PD-1 antibody).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03598816</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6326</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_263"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6326</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>neoantigen DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007709 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007709">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007709</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of patient-specific antigens, which are immunogenic and unique to the patient&apos;s tumor, with potential immunomodulating and antineoplastic activities. The neoantigen peptide vaccine, the peptides stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the neoantigens, which results in tumor cell lysis. Personalized neo-antigen peptide vaccine is a product combines multiple patient specific neo-antigens. Given personalized neo-antigen peptide vaccine together with Th1 polarizing adjuvant poly ICLC may induce a polyclonal, poly-epitope, cytolytic T cell immunity against the patient&apos;s tumor. Patients also receive nivolumab.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C165508</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05098210</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6327</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6327</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>neoantigen peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007710 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007710</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of synthetic long peptides (SLPs), ranging from 20-35 amino acids in size, that are derived from two or more of the patient&apos;s tumor-specific mutant antigens (TSMAs), with potential immunostimulatory and antitumor activities. SLP vaccine may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL)-mediated immune response against the TSMAs expressed by the tumor cells. This vaccine is a optimized neoantigen synthetic long peptide (SLP) vaccines for pancreatic cancer patients following neoadjuvant chemotherapy. The neoantigen SLP vaccines will incorporate prioritized neoantigens and will be co-administered with poly-ICLC. It can be used in combination with chemoradiation with temozolomide for patients with newly diagnosed glioblastoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C150471</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02510950</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05111353</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6332</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6332</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>neoantigen synthetic long peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007711 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007711</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of autologous DCs loaded with immunogenic peptides derived from autologous cancer cells, with potential immunomodulating and antineoplastic activities. Vaccination with the neoantigen-loaded autologous DC vaccine stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the neoantigens, which results in tumor cell lysis. Neoantigens arising from the mutations of the tumor genome expressed specifically on the tumor cell instead of normal cells, suggesting that vaccines targeting neoantigens should generate a highly tumor-specific response with minimal off-target effects. Neoantigens are identified from tumor tissues from a gastric cancer, hepatocellular carcinoma, lung cancer or colorectal cancer patient. Dendritic cells are then primed with synthesized peptides. The vaccine can be combined with microwave ablation ti treat patients with Hepatocellular Carcinoma (HCC). It can also be combined with Anti-PD1 (Nivolumab) as for patients with resected Hepatocellular Carcinoma (HCC) and Liver Metastases From Colorectal Cancer (CRLM). </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119> NCT: https://clinicaltrials.gov/study/NCT03871205</obo:IAO_0000119>
        <obo:IAO_0000119> NCT: https://clinicaltrials.gov/study/NCT04147078</obo:IAO_0000119>
        <obo:IAO_0000119> NCT: https://clinicaltrials.gov/study/NCT04912765]</obo:IAO_0000119>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C141422</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03674073</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6281</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6281</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>neoantigen-loaded autologous dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007712 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007712</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is made from the subject&apos;s blood cells and is designed to interact in the patient&apos;s body with cells that are programmed to fight specific tumor proteins NY-ESO-1, Melanoma Antigen Gene-A1 (MAGE-A1) and Melanoma Antigen Gene-A3 (MAGE-A3). The vaccine can be given in combination with decitabine which may increase the amount and activity of these cancer proteins on the surface of tumor cells to increase the possibility that the vaccine will stimulate cells to act against the tumor cells. The dendritic cells may stimulate CD4 and CD8 antigen specific T cells in patients with relapsed or refractory pediatric high grade gliomas, medulloblastomas, and central nervous system primitive neuroectodermal tumors (CNS PNETs).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02332889</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6367</obo:IAO_0000119>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>4100</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6367</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGE-A1</rdfs:comment>
        <rdfs:comment>Gene name: MAGE-A3</rdfs:comment>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:label>NY-ESO-1, MAGE-A1, and MAGE-A3 dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007713 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007713">
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007713</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of synthetic peptides derived from the cancer-testis antigen NY-ESO-1, preferentially expressed antigen in melanoma (PRAME), human melanoma antigen A3 (MAGE-A3) and the human Wilms tumor protein-1 (WT-1), with potential immunostimulating and antineoplastic activities. NY-ESO-1/PRAME/MAGE-A3/WT-1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing NY-ESO-1, PRAME, MAGE-A3 and WT-1, resulting in tumor cell lysis. As proteins are degraded in cells, peptides are presented on the surface of these cells as a complex with tissue type molecules (HLA molecules). T-cells may then recognize the peptide-HLA complexes, via its T-cell receptor, potentially resulting in tumor-cell killing, if sufficient priming takes place. Cancer testis antigens (CTA&apos;s) are known to be immunogenic and are only expressed at immunoprivileged sites, thus out of reach of immune responses, and on cancer cells, making them ideal targets for therapeutic cancer vaccination. The CTA&apos;s chosen were NY-ESO-1, MAGE-A3 and PRAME. WT-1 is additionally included as this protein has proven to be an important antigen in hematological malignancies. It is combined with azacitidine for treatment of patients with high-risk myelodysplastic syndrome or acute myeloid leukemia. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C127125</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02750995</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6329</obo:IAO_0000119>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:OGG_0000000006>23532</obo:OGG_0000000006>
        <obo:OGG_0000000006>4102</obo:OGG_0000000006>
        <obo:OGG_0000000006>7490</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6329</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: MAGE-A3</rdfs:comment>
        <rdfs:comment>Gene name: NY-ESO-1</rdfs:comment>
        <rdfs:comment>Gene name: PRAME</rdfs:comment>
        <rdfs:comment>Gene name: WT-1</rdfs:comment>
        <rdfs:label>NY-ESO-1/PRAME/MAGE-A3/WT-1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007714 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007714">
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007714</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with autologous DCs that are pulsed with HOCl-oxidized autologous tumor lysate (OCDC) and administered in prime phase, along with a personal neoantigen-sensitized DC(NeoDC) vaccine administered in the boost phase for Esophageal Squamous Cell Carcinoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05317325</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6331</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_5041"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6331</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>OCDC and NeoDC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007715 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007715">
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007715</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of autologous ovarian cancer antigens obtained from hydrolyzed, inactivated blood and tumor tissue of patients with ovarian cancer, with potential immunostimulatory and antineoplastic activities. The ovarian cancer antigens stimulate the immune system and activate a cytotoxic T-lymphocyte (CTL) immune response against ovarian cancer cells. Ovarian cancer patients can be given one pill a day for three months. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C159540</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03556566</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6354</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000886"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2394"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6354</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>oral cancer vaccine V3-OVA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007716 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007716">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007716</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of the tumor-associated antigen (TAA) oligosaccharide antigen sialyl Lewis A (CA19-9; sialylated Lewis A antigen; carbohydrate antigen 19-9; cancer antigen 19-9), with potential immunostimulating and antineoplastic activities. Oral therapeutic vaccine V3-X induces a cytotoxic T-lymphocyte (CTL)-mediated immune response against tumor cells expressing CA19-9. Cholangiocarcinoma (CCA) is a malignant neoplasm originating from the epithelial cells lining the intra- or extrahepatic biliary ducts. This immunotherapeutic formulation is made from pooled heat- and chemically-inactivated blood from donors with CCA for a pill for cholangiocarcinoma patients.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C148144</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03042182</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6333</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6333</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>oral therapeutic vaccine V3-X</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007717 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007717</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine comprised of three immunogenic tetanus toxoid epitope P30-linked tumor-associated antigen (TAA) peptides, P30-linked Ephrin receptor A2 (EphA2), P30-linked cytomegalovirus (CMV) matrix protein pp65 (65 kDa lower matrix phosphoprotein; UL83) and P30-linked survivin, with potential immunostimulating and antineoplastic activities. The vaccine may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing EphA2, CMV pp65 and survivin. Hiltonol is used as an adjuvant to stimulate or enhance the activation of your immune system. The vaccine and adjuvant may help treat HLA-A*0201 positive patients with a newly diagnosed, unmethylated, and untreated World Health Organization (WHO) grade IV malignant glioma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C187131</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05283109</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6362</obo:IAO_0000119>
        <obo:OGG_0000000006>1969</obo:OGG_0000000006>
        <obo:OGG_0000000006>332</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6362</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EphA2</rdfs:comment>
        <rdfs:comment>Gene name: survivin</rdfs:comment>
        <rdfs:label>P30-linked EphA2/CMV pp65/survivin peptide vaccine P30-EPS</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0007718 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007718</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made up of CPC-P501 protein formulated with the adjuvant AS15. Patients with hormone-sensitive prostate cancer and rising PSA, after primary tumor treatment, can be treated with the P501-AS15 vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00148928</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6335</obo:IAO_0000119>
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        <obo:VO_0001818>6335</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>P501-AS15 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007719 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007719</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine based on next-generation sequencing and major histocompatibility complex affinity prediction algorithm, which may help treat patients with pancreatic ductal adenocarcinoma. This vaccine may elicit measurable neoantigen-specific immunologic responses in patients.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03558945</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6341</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6341</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>pancreatic tumor personalized neoantigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007720 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007720</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of a peptide derived from the tumor-associated antigen (TAA) and immune checkpoint molecule programmed cell death-1 ligand 1 (PD-L1) combined with the immunoadjuvant montanide ISA-51, with potential immunomodulating and antineoplastic activities. Vaccination with PD-L1 peptide vaccine may activate the immune system to induce an immune response against PD-L1-expressing cells. This may increase and restore the proliferation and activation of various immune cells, including cytotoxic T-lymphocytes (CTLs), and may eradicate PD-L1-expressing tumor cells. The vaccines aims to stimulate PD-L1 specific T-cells, hence eliminating both PD-L1 positive tumor cells as well as PD-L1 positive immunosuppressive and antigen presenting cells in the tumor microenvironment. It has been used in clinical trials for patients with multiple melanoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C148146</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03042793</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6338</obo:IAO_0000119>
        <obo:OGG_0000000006>29126</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6338</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PD-L1</rdfs:comment>
        <rdfs:label>PD-L1 peptide vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007721 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007721">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007721</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine composed of IO103, a peptide derived from the tumor-associated antigen (TAA) programmed cell death-1 ligand 1 (PD-L1), IO102, the 21-mer peptide vaccine derived from the immunomodulatory enzyme indoleamine 2,3-dioxygenase (IDO), and the immunoadjuvant montanide ISA-51, with potential immunomodulating and antineoplastic activities. Both IDO and PD-L1 reactive CD8 T cells are cytotoxic and can kill cancer cells and immune regulatory cells in vitro. Thus boosting specific T cells that recognize immune regulatory proteins such as IDO and PD-L1 may directly modulate immune regulation. The the programmed death 1 (PD-1) regulatory antibody Nivolumab may further help treat patients with metastatic melanoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C148154</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03047928</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6337</obo:IAO_0000119>
        <obo:OGG_0000000006>29126</obo:OGG_0000000006>
        <obo:OGG_0000000006>3620</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
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        <obo:VO_0001818>6337</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: IDO</rdfs:comment>
        <rdfs:comment>Gene name: PD-L1</rdfs:comment>
        <rdfs:label>PD-L1/IDO peptide vaccine IO102-103</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007722 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007722">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007722</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine designed to target the unique immunogenic mutations arising in each patient&apos;s tumor. Peptide binding to MHC is a critical gateway to both the initiation of a T-cell immune response by the antigen presenting cell (APC), and to the detection and elimination of tumor cells presenting the particular peptide by the stimulated cytotoxic T lymphocyte (CTL). The attraction of neoantigens as cancer targets for the immune system results from the structural and geographical features of the mutation. Neoantigen peptides are only found in tumor cells, so CTLs should show exquisite specificity, reducing the opportunity for autoimmune disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:25101225</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6387</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6387</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>personal neoantigen cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007723 -->

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        <obo:IAO_0000115>A cancer vaccine co-administered with poly-ICLC, nivolumab, and rituximab (or another monoclonal antibody against CD20) to treat Follicular Lymphoma. The peptides comprising the vaccine are reconstituted in up to 4 pools with 5 peptides per pool (A, B, C, and D).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03121677</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6342</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6342</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>personalized follicular lymphoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007724 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007724</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that may stimulate the immune system to react to lung cancer cells, in combination with Cyclophosphamide.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02419170</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6340</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6340</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>personalized mature dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007725 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007725</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine for melanoma. Melanomas have mutations (changes in genetic material) that are specific to an individual patient and tumor. These mutations can cause the tumor cells to produce proteins that appear very different from the body&apos;s own cells. These proteins used in a vaccine may induce strong immune responses, which may help the participant&apos;s body fight any tumor cells that could cause the melanoma to come back in the future. NeoVax is a long-peptide vaccine targeting up to 20 personal neoantigens per patient for patients with surgically resected stage IIIB/C or IVM1a/b melanoma. There was long-term persistence of neoantigen-specific T cell responses following vaccination, with ex vivo detection of neoantigen-specific T cells exhibiting a memory phenotype, as well as diversification of neoantigen-specific T cell clones over time, with emergence of multiple T cell receptor clonotypes exhibiting distinct functional avidities. There was also tumor infiltration by neoantigen-specific T cell clones after vaccination and epitope spreading, suggesting on-target vaccine-induced tumor cell killing. Personal neoantigen peptide vaccines thus induce T cell responses that persist over years and broaden the spectrum of tumor-specific cytotoxicity in patients with melanoma. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01970358</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:33479501</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6375</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6375</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>personalized neoantigen melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007726 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007726</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that contains 6 synthetic peptides mixed with the adjuvant Montanide™. The peptides were selected to induce T cell responses against 12 dominant epitopes from 7 cancer testis antigens (CTAs), which are the most frequently expressed CTAs in colorectal cancer. The 6 peptides were optimized to induce long lasting CRC specific T cell responses. Colorectal cancer peptide vaccine PolyPEPI1018 potentially elicits a cytotoxic T-lymphocyte response against colorectal tumors expressing the CTAs associated with the vaccine, which may result in a reduction in tumor cell proliferation. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C154278</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03391232</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6343</obo:IAO_0000119>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9256"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6343</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:label>PolyPEPI1018 CRC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007727 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007727">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007727</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of whole irradiated heterologous melanoma cells which express multiple melanoma-related antigens. Polyvalent melanoma vaccine may stimulate an antitumoral cytotoxic T-cell immune response in the host, resulting in inhibition of tumor cell proliferation and tumor cell death. Vaccines may make the body build an immune response and kill tumor cells. Interleukin-2 may stimulate a person&apos;s white blood cells to kill tumor cells. Interferon alfa-2b may interfere with the growth of tumor cells. Treatment with this combination may help treat melanoma. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C1633</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00004104</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6344</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6344</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>polyvalent melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007728 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007728">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007728</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with autologous dendritic cells targeting prostate cancer (PC)-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon administration of prodencel, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against PC cells expressing the antigen(s), resulting in tumor cell lysis. (NCIT_C192174) The vaccine could help treat patients with metastatic castration-resistant prostate cancer (mCRPC) after novel androgen-deprived therapy and docetaxel chemotherapy failure.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>prodencel</obo:IAO_0000118>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C192174</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05533203</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6345</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6345</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>prodencel vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007729 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007729</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing the mammalian expression vector pUMVC3 encoding epitopes derived from three tumor-associated antigens (TAAs): human insulin-like growth factor-binding protein 2 (IGFBP2), human epidermal growth factor receptor 2 (HER2; ERBB2) and insulin-like growth factor 1 receptor (IGF1R), with potential immunostimulating and antineoplastic activities. The vaccine This activates the immune system to mount a combined response from specific T helper type 1 (Th1) cells, memory T-cells and cytotoxic T-lymphocytes (CTL) against IGFBP2-, HER2-, and IGF1R-expressing tumor cells. This vaccine may prevent cancer from coming back in patients with non-metastatic, node positive, human epidermal growth factor receptor (HER)2 negative breast cancer in which all signs and symptoms have disappeared. Vaccines made from deoxyribonucleic acid (DNA) may help the body build an effective immune response to kill tumor cells. It is given in combination with sargramostim.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C127910</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT02780401</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6346</obo:IAO_0000119>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:OGG_0000000006>3480</obo:OGG_0000000006>
        <obo:OGG_0000000006>3485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6346</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: HER2</rdfs:comment>
        <rdfs:comment>Gene name: IGF1R</rdfs:comment>
        <rdfs:comment>Gene name: IGFBP2</rdfs:comment>
        <rdfs:label>pUMVC3-IGFBP2-HER2-IGF1R plasmid DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007730 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007730</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing seven 17 amino acids long synthetic RAS oncogene-encoded peptides representing the most common codon 12 and 13 oncogenic mutations in Kirsten rat sarcoma viral oncogene homolog (KRAS), with potential immunomodulating and antineoplastic activities. The vaccine may stimulate a specific CD4-positive helper T-lymphocyte- and cytotoxic T-lymphocyte (CTL)-mediated immune response against RAS mutant-specific-expressing cancer cells, resulting in an inhibition of tumor cell proliferation and tumor cell death. The vaccine can be given in combination with Balstilimab and QS-21 for patients with pancreatic cancer to increase efficacy. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C200465</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05638698</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6356</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000692"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1793"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6356</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>RAS peptide cancer vaccine TG01</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007731 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007731</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that encodes a melanoma antigen tyrosinase-related protein 2 (TRP2) cytotoxic T-lymphocyte (CTL) epitope and a modified monoclonal antibody, a chimera of human IgG1/murine IgG2a with T cell mimotopes expressed within the complementarity-determining regions (CDR) of the antibodies, with potential immunostimulating and antineoplastic activities. The melanoma TRP2 CTL epitope vaccine SCIB1 expresses the modified antibody. Subsequently, the Fc component of the engineered antibody targets and binds to the CD64 receptor on the dendritic cells (DCs); upon processing by DCs, the cellular immune system may be activated to induce helper T-cell and CTL immune responses against tumor cells expressing the TRP2 antigen. SCIB1 can be used in combination with either nivolumab (Opdivo) with ipilimumab (Yervoy) or pembrolizumab (Keytruda), standard treatments approved for patients with advanced melanoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C91380</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04079166</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6349</obo:IAO_0000119>
        <obo:OGG_0000000006>1638</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6349</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TRP-2</rdfs:comment>
        <rdfs:label>SCIB1 DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007732 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007732</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with secPD-L1, a splice variant of PD-L1 (programmed death ligand-1, an immune checkpoint pathway) that does not splice into the transmembrane domain, but instead produces a secreted form of PD-L1 that has a unique 18 amino acid tail containing a cysteine that allows it to homodimerize and more effectively inhibit lymphocyte function than monomeric soluble PD-L1. Recombinant secPD-L1 can dimerize and inhibit T-cell proliferation and IFN-gamma production in vitro. SecPD-L1 may function as a paracrine negative immune regulator within the tumor, since secPD-L1 does not require a cell-to-cell interaction to mediate its inhibitory effect. This could lead to improved survival for patients with numerous types of cancers, including lung cancer, melanoma, renal cell carcinoma, and Hodgkin lymphoma.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:30564891</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6376</obo:IAO_0000119>
        <obo:OGG_0000000006>29126</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6376</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: PD-L1</rdfs:comment>
        <rdfs:label>secPD-L1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007733 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007733">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007733</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that consists of the oligosaccharide antigen sialyl Lewis (CA19-9) conjugated to the nonspecific immunomodulator keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. The sialyl Lewis-keyhole limpet hemocyanin conjugate vaccine may induce production of IgG and IgM antibodies as well as trigger an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing the sialyl Lewis antigen. The vaccine therapy together with QS21 may cause a stronger immune response and kill more tumor cells. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C69000</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00470574</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6350</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>6350</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>sialyl lewis-keyhole limpet hemocyanin conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007734 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007734</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine consisting of peptides derived from melanoma-associated antigens and a modified T-cell epitope derived from tetanus toxoid. Vaccination with this agent may stimulate a host cytotoxic and helper T-cell response against tumor cells expressing melanoma-associated antigens, resulting in decreased tumor growth. This vaccine is compromised of multi-epitope melanoma peptide vaccine (12MP) and 1 tetanus peptide melanoma vaccine emulsified with GM-CSF and ISA-51 (incomplete Freund&apos;s adjuvant).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C2468</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00071981</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6355</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1909"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6355</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>tetanus peptide melanoma vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007735 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007735</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made with GMCSF transgene that directly stimulates increased expression of tumor antigen(s) and enhances dendritic cell migration to the vaccination site. TGFβ2 blockade following intracellular TGFβ2 antisense gene expression reduces production of immune inhibiting activity at the vaccine site. This vaccine integrates enhancement of an anticancer immune response concurrently with a reduction in cancer-induced immune suppression. Autologous cancer cells are harvested from patients with advanced refractory cancer, and a TGFβ2 antisense / GMCSF expression vector plasmid is constructed. The autologous cancer tissue is irradiated and electrocorporated with the vector. </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00684294</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6357</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6357</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>TGFβ2 antisense-GMCSF gene modified autologous tumor cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007736 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007736</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine containing autologous dendritic cells (DCs) that are loaded with total tumor RNA (TTRNA) from a specific tumor, with potential immunostimulatory and antineoplastic activities. The vaccine may elicit a highly specific cytotoxic T-cell (CTL) response against the tumor-associated antigens (TAAs) encoded by the TTRNA. The vaccine can be given in combination with Temozolomide (TMZ) and Autologous Hematopoietic Stem Cells (HSC).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C116913</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT03396575</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6360</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6360</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>total tumor RNA-loaded dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007737 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007737</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made as patient&apos;s lymphocytes are rendered transgenic for a gene coding for selected portion of telomerase an enzyme expressed in the vast majority of cancer cells. Transgenic cells are then returned to the patient to produce an immune response targeted at cancer cells expressing telomerase. The transgenic cells serve as antigen- presenting cells (APCs) with the dual function of antigen synthesis and presentation. Vaccination produces an immune response targeting cancer cells expressing telomerase.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C38720</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00061035</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:12653092</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6358</obo:IAO_0000119>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
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        <obo:VO_0001818>6358</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: telomerase</rdfs:comment>
        <rdfs:label>transgenic lymphocyte immunization vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007738 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007738</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine of 3 adenoviral vaccines (ETBX-011, ETBX-051 &amp; ETBX-061). ETBX-011 uses a replication-defective, E1- and E2b-deleted oncolytic adenoviral serotype 5 (Ad5) encoding an epitope of human carcinoembryonic antigen (CEA). ETBX-051 is composed of a replication-defective, serotype 5 adenovirus (Ad5) with the viral genes early 1 (E1), early 2b (E2b), and early 3 (E3) deleted, and the human transcription factor brachyury encoded. ETBX-061 composed of a replication-defective, serotype 5 adenovirus (Ad5) with the viral genes early 1 (E1), early 2b (E2b), and early 3 (E3) deleted, and the human glycoprotein mucin 1 (MUC1) encoded. The three of these vaccines act against tumor associated antigens and have potential immunostimulating and antineoplastic activities. The TriAd vaccine can be used in combination with Anti-PD-L1/TGF-beta trap (M7824) and Anktiva (N-803) to shrink previously untreated head and neck tumors before surgery or stop the tumors from coming back after all treatment.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C91373</obo:IAO_0000119>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C143034</obo:IAO_0000119>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C143035</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT04247282</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6359</obo:IAO_0000119>
        <obo:OGG_0000000006>1048</obo:OGG_0000000006>
        <obo:OGG_0000000006>4582</obo:OGG_0000000006>
        <obo:OGG_0000000006>6862</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6359</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEA</rdfs:comment>
        <rdfs:comment>Gene name: MUC1</rdfs:comment>
        <rdfs:comment>Gene name: brachyury</rdfs:comment>
        <rdfs:label>TriAd cancer vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007739 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007739">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007739</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that can be used in combination with Neo-antigen DC vaccine and their sensitized T cells for the treatment of esophageal cancer, advanced malignant melanoma, bladder cancer and colorectal cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05023928</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT05235607</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6361</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6361</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>tumor antigen-sensitized DC vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007740 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007740</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine that is composed of dendritic cells pulsed with tumor cells lysates that stimulate a potent and specific cell mediated anti-tumor immune response. It can be used in combination with high-dose chemotherapy and hematopoietic stem cell transplantation (HSCT). The combination may increase overall survival and progression-free survival for patients with high-risk pediatric and young adult tumors (localized solid tumors such as, sarcoma, neuroblastoma, and Wilms&apos; tumor). </obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C1988</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00405327</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6366</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6366</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>tumor lysate-pulsed dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007741 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007741</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made from proteins from the patient&apos;s tumor cells may boost the body&apos;s immune response against the tumor. The effects of chemotherapy on the immune system can potentially make immunotherapy more effective if administered soon after completion of chemotherapy. The addition of recombinant human IL-7 (interleukin 7) (rhIL-7 (recombinant human interleukin 7)) may make the immunotherapy more effective. Alpha cluster of differentiation 25 (CD25) and 8H9 depleted autologous lymphocytes plus tumor lysate/keyhole limpet hemocyanin (KLH) pulsed dendritic cell vaccines plus or minus r-hIL7 (CYT107) may induce immune responses to tumor lysate in patients (with Ewing&apos;s sarcoma, rhabdomyosarcoma or neuroblastoma).</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT00923351</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6365</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1115"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6365</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>tumor lysate/KLH pulsed dendritic cell vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007742 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007742">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007658"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007742</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine made as the patient&apos;s cancer will be surgically removed to provide cells for the vaccine, then the patient will be vaccinated twice with those cells and GM-CSF. After, the patient&apos;s blood will be filtered for white cells which will then be cultured and stimulated to reach a higher (killer) activity level. Next, the activated white blood cells will be infused into the patient&apos;s bloodstream so that they will be able to attack the cancer. Lastly, the entire process starting with vaccination will be repeated, for a total of two rounds of therapy. The autologous vaccine-enhanced ex vivo activated cancer neoantigens-specific T-cells TVI-Brain-1 recognize and bind to tumor cells expressing the cancer neoantigens, resulting in a cytotoxic T-lymphocyte (CTL)-mediated immune response against the patient&apos;s tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>NCI: https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;ns=ncit&amp;code=C199632</obo:IAO_0000119>
        <obo:IAO_0000119>NCT: https://clinicaltrials.gov/study/NCT01081223</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6373</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6373</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>TVI-Brain-1 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007743 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007743">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005487"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007658"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007743</metadata:prefixIRI>
        <obo:IAO_0000115>A cancer vaccine administered within the first 2 to 3 months after allogeneic stem cell transplantation may enhance graft-vs.-leukemia responses. Irradiated autologous cancer cells provide a source of tumor antigens at the vaccination site. Granulocyte macrophage colony-stimulating factor (GM-CSF) secreted by irradiated bystander cells stimulates the recruitment, maturation and immunostimulatory activity of dendritic cells (DCs) at the vaccination site. Autologous whole tumor cell-based vaccination may tip the balance between leukemia-specific and alloreactive T cell responses in favor of a graft-vs.-leukemia (GvL) effect.</obo:IAO_0000115>
        <obo:IAO_0000117>Hayleigh Kahn</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24482749</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=6388</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1240"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>6388</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>whole tumor cell-based leukemia vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007747 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007747">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007747</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine role that indicates a vaccine has received emergency use authorization (EUA) from regulatory authorities for distribution and administration to the public.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>authorized vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007748 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007748">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000439"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001485"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007748</metadata:prefixIRI>
        <obo:IAO_0000115>USA licensed vaccine for veterinary uses approved by USDA. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>USDA licensed vaccine</obo:IAO_0000118>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>USA licensed veterinary vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0007749 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0007749">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001469"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001469"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001528"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_691956"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0007749</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_8835"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_691956"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed duck vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010842"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010000</metadata:prefixIRI>
        <obo:IAO_0000115>A Cp12 protein that is part of Crptosporidium parvum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Cp12 from Crptosporidium parvum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010842"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010001</metadata:prefixIRI>
        <obo:IAO_0000115>A Cp21 protein that is part of Crptosporidium parvum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Cp21 from Crptosporidium parvum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010842"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010002</metadata:prefixIRI>
        <obo:IAO_0000115>A Cp15 protein that is part of Crptosporidium parvum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Cp15 from Crptosporidium parvum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010842"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010003</metadata:prefixIRI>
        <obo:IAO_0000115>A CP60 protein that is part of Crptosporidium parvum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Cp60 from Crptosporidium parvum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010004">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010004</metadata:prefixIRI>
        <obo:IAO_0000115>A Cp23 protein that is part of Crptosporidium parvum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0011308"/>
        <rdfs:label>obsolete Crptosporidium parvum Cp23</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010842"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010005</metadata:prefixIRI>
        <obo:IAO_0000115>A CpP2 protein that is part of Crptosporidium parvum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>CpP2 from Crptosporidium parvum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010822"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010006</metadata:prefixIRI>
        <obo:IAO_0000115>A 3-1E protein that is part of Eimeria acervulina</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Eimeria acervulina 3-1E</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010833"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010007</metadata:prefixIRI>
        <obo:IAO_0000115>A gam56 protein that is part of Eimeria maxima</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Eimeria maxima gam56</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010008">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010008</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine role that is characteristic of an inactivated vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>inactivated vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010829"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010009</metadata:prefixIRI>
        <obo:IAO_0000115>A a1-giardin protein that is part of Giardia  duodenalis</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Giardia  duodenalis a1-giardin</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 5697168</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010010">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015483"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010010</metadata:prefixIRI>
        <obo:IAO_0000115>A a1-giardin protein that is part of Giardia  lamblia</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Giardia  lamblia a1-giardin</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 5697168</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015483"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010011</metadata:prefixIRI>
        <obo:IAO_0000115>A alpha-enolase protein that is part of Giardia  lamblia</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Giardia  lamblia alpha-enolase</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 2023</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010012">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015483"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010012</metadata:prefixIRI>
        <obo:IAO_0000115>A CWP2 protein that is part of Giardia  lamblia</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Giardia  lamblia CWP2</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 5703171</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010013</metadata:prefixIRI>
        <obo:IAO_0000115>A Acen1 protein that is part of Leishmania  donovani</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  donovani Acen1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010014</metadata:prefixIRI>
        <obo:IAO_0000115>A Beta-tubulin protein that is part of Leishmania  donovani</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  donovani Beta-tubulin</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 13392307</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010015">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010015</metadata:prefixIRI>
        <obo:IAO_0000115>A FML protein that is part of Leishmania  donovani</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  donovani FML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010016</metadata:prefixIRI>
        <obo:IAO_0000115>A Gp63 protein that is part of Leishmania  donovani</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  donovani Gp63</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 13389283</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010017</metadata:prefixIRI>
        <obo:IAO_0000115>A HASPB1 protein that is part of Leishmania  donovani</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  donovani HASPB1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010018</metadata:prefixIRI>
        <obo:IAO_0000115>A KH protein that is part of Leishmania  donovani</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  donovani KH</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010019</metadata:prefixIRI>
        <obo:IAO_0000115>A LdyGCS protein that is part of Leishmania  donovani</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  donovani LdyGCS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010020</metadata:prefixIRI>
        <obo:IAO_0000115>A NH36 protein that is part of Leishmania  donovani</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  donovani NH36</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010021">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010021</metadata:prefixIRI>
        <obo:IAO_0000115>A P1 protein that is part of Leishmania  donovani</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  donovani P1</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 13388831</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010836"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010022</metadata:prefixIRI>
        <obo:IAO_0000115>A A2 protein that is part of Leishmania  infantum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  infantum A2</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 13387764</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010023 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010023">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010836"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010023</metadata:prefixIRI>
        <obo:IAO_0000115>A HSP70 II protein that is part of Leishmania  infantum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania infantum HSP70 II</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 5073319</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010024">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010024</metadata:prefixIRI>
        <obo:IAO_0000115>A KMP-11 protein that is part of Leishmania  major</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  major KMP-11</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 13387683</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010025 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010025">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010025</metadata:prefixIRI>
        <obo:IAO_0000115>A LmSTI1 protein that is part of Leishmania  major</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  major LmSTI1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010026</metadata:prefixIRI>
        <obo:IAO_0000115>A LIPO-A protein that is part of Leishmania  major</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  major LIPO-A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010027</metadata:prefixIRI>
        <obo:IAO_0000115>A P36 protein that is part of Leishmania  major</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  major P36</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010028">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010028</metadata:prefixIRI>
        <obo:IAO_0000115>A PEPCK protein that is part of Leishmania  major</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  major PEPCK</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 5649768</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010029</metadata:prefixIRI>
        <obo:IAO_0000115>A LeIF protein that is part of Leishmania  major</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania  major LeIF</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 12981542</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010030">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010030</metadata:prefixIRI>
        <obo:IAO_0000115>A MIC3 protein that is part of Neospora caninum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum MIC3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010031">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010031</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA2 protein that is part of Neospora caninum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum GRA2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010032">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010032</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA6 protein that is part of Neospora caninum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum GRA6</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010033</metadata:prefixIRI>
        <obo:IAO_0000115>A SRS2 protein that is part of Neospora caninum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum SRS2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010034</metadata:prefixIRI>
        <obo:IAO_0000115>A MIC10 protein that is part of Neospora caninum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum MIC10</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010035">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010035</metadata:prefixIRI>
        <obo:IAO_0000115>A p24 protein that is part of Neospora caninum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum p24</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010036</metadata:prefixIRI>
        <obo:IAO_0000115>A PDI protein that is part of Neospora caninum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum PDI</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010037 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010037">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010037</metadata:prefixIRI>
        <obo:IAO_0000115>A SAG1 protein that is part of Neospora caninum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum SAG1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010038">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000615"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010038</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine role that is characteristic of a live attenuated vaccine. </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>role</oboInOwl:inSubset>
        <rdfs:label>live attenuated vaccine role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010039 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010039">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015475"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010039</metadata:prefixIRI>
        <obo:IAO_0000115>A P36p protein that is part of Plasmodium berghei</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium berghei P36p</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010040</metadata:prefixIRI>
        <obo:IAO_0000115>A ABRA protein that is part of Plasmodium falciparum|An ABRA protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum ABRA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010041">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010041</metadata:prefixIRI>
        <obo:IAO_0000115>A EBA-175 RII protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum EBA-175 RII</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010042">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010042</metadata:prefixIRI>
        <obo:IAO_0000115>A Hsp90 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum Hsp90</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010043">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010043</metadata:prefixIRI>
        <obo:IAO_0000115>A MSP1 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum MSP1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010044">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010044</metadata:prefixIRI>
        <obo:IAO_0000115>A RESA protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum RESA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010045">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010045</metadata:prefixIRI>
        <obo:IAO_0000115>A MSP2 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum MSP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010046">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010046</metadata:prefixIRI>
        <obo:IAO_0000115>A MSP4 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum MSP4</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010047</metadata:prefixIRI>
        <obo:IAO_0000115>A Pf ribosomal protein P0 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum Pf ribosomal protein P0</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010048 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010048">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010048</metadata:prefixIRI>
        <obo:IAO_0000115>A PfCelTOS protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum PfCelTOS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010049">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010049</metadata:prefixIRI>
        <obo:IAO_0000115>A PfSSP2 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum PfSSP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010050</metadata:prefixIRI>
        <obo:IAO_0000115>A LSA1 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum LSA1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010051</metadata:prefixIRI>
        <obo:IAO_0000115>A Pfen protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum Pfen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010052 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010052">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010052</metadata:prefixIRI>
        <obo:IAO_0000115>A Pfs230 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum Pfs230</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010053 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010053">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010053</metadata:prefixIRI>
        <obo:IAO_0000115>A Pfs25 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum Pfs25</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010054</metadata:prefixIRI>
        <obo:IAO_0000115>A Pfs48 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum Pfs48</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010055">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010055</metadata:prefixIRI>
        <obo:IAO_0000115>A RH5 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum RH5</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010056 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010056">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010056</metadata:prefixIRI>
        <obo:IAO_0000115>A TRAP protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum TRAP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010057 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010057">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010057</metadata:prefixIRI>
        <obo:IAO_0000115>A Pfs45 protein that is part of Plasmodium falciparum</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000258"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum Pfs45</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010058 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010058">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015472"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000393"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010058</metadata:prefixIRI>
        <obo:IAO_0000115>A PkCSP protein that is part of Plasmodium knowlesi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000393"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium knowlesi PkCSP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010059 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010059">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015472"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010059</metadata:prefixIRI>
        <obo:IAO_0000115>A PkSSP2 protein that is part of Plasmodium knowlesi|A SSP2 protein that is part of Plasmodium knowlesi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000118>Plasmodium vivax Thrombospondin-related apical merozoite protein</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium knowlesi SSP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010060">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015472"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000393"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010060</metadata:prefixIRI>
        <obo:IAO_0000115>A PkAMA1 protein that is part of Plasmodium knowlesi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000393"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium knowlesi PkAMA1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010061">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015472"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000394"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010061</metadata:prefixIRI>
        <obo:IAO_0000115>A PkMSP1 protein that is part of Plasmodium knowlesi|A PkMSP1p42 protein that is part of Plasmodium knowlesi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000394"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium knowlesi PkMSP1p42</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010062">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015473"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000327"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010062</metadata:prefixIRI>
        <obo:IAO_0000115>A CelTOS protein that is part of Plasmodium vivax|A PvCelTOS protein that is part of Plasmodium vivax</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000327"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium vivax CelTOS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010063 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010063">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015473"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000327"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010063</metadata:prefixIRI>
        <obo:IAO_0000115>A CS protein that is part of Plasmodium vivax|A PvCS protein that is part of Plasmodium vivax</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000327"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium vivax CS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010064">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015473"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000328"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010064</metadata:prefixIRI>
        <obo:IAO_0000115>A DBPII protein that is part of Plasmodium vivax|A PvDBPII protein that is part of Plasmodium vivax</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000328"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium vivax PvDBPII</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010065 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010065">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015473"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000327"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010065</metadata:prefixIRI>
        <obo:IAO_0000115>A TRAP protein that is part of Plasmodium vivax</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000327"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium vivax TRAP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010066">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010066</metadata:prefixIRI>
        <obo:IAO_0000115>A HEP17 protein that is part of Plasmodium yoelii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii HEP17</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010067 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010067">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000385"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000387"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010067</metadata:prefixIRI>
        <obo:IAO_0000115>A HSP60 protein that is part of Plasmodium yoelii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000385"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000386"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000387"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>PMC98419 citation for occurance in all lifestages</rdfs:comment>
        <rdfs:label>Plasmodium yoelii HSP60</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010068 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010068">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000385"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010068</metadata:prefixIRI>
        <obo:IAO_0000115>A SSP2 protein that is part of Plasmodium yoelii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000385"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii SSP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010069 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010069">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010069</metadata:prefixIRI>
        <obo:IAO_0000115>A ASP-1 protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi ASP-1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010070 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010070">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010070</metadata:prefixIRI>
        <obo:IAO_0000115>A CRP protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi CRP</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 947867</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010071 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010071">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010071</metadata:prefixIRI>
        <obo:IAO_0000115>A G1 protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi G1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010072 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010072">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010072</metadata:prefixIRI>
        <obo:IAO_0000115>A PAR3 protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi PAR3</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 3540497</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010073">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010073</metadata:prefixIRI>
        <obo:IAO_0000115>A PFR Ag protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi PFR Ag</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010074 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010074">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010074</metadata:prefixIRI>
        <obo:IAO_0000115>A rTcENO from H8 protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi rTcENO from H8</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010075">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010075</metadata:prefixIRI>
        <obo:IAO_0000115>A Tc24 protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi Tc24</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010076</metadata:prefixIRI>
        <obo:IAO_0000115>A Tc80 protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi Tc80</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010077 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010077">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010077</metadata:prefixIRI>
        <obo:IAO_0000115>A TcENO protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi TcENO</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010078 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010078">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010078</metadata:prefixIRI>
        <obo:IAO_0000115>A TcSSP4 protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi TcSSP4</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010079 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010079">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010079</metadata:prefixIRI>
        <obo:IAO_0000115>A TcTASV-C protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi TcTASV-C</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010080</metadata:prefixIRI>
        <obo:IAO_0000115>A TCTS-154 protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi TCTS-154</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010081 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010081">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010081</metadata:prefixIRI>
        <obo:IAO_0000115>A Trans-salidase protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi Trans-salidase</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 3537653</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010082 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010082">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010082</metadata:prefixIRI>
        <obo:IAO_0000115>A TSA-1 protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi TSA-1</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 3544076</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010083 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010083">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010083</metadata:prefixIRI>
        <obo:IAO_0000115>A TsF protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi TsF</rdfs:label>
        <rdfs:seeAlso>NCBI Gene ID 3537653</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010084 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010084">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010084</metadata:prefixIRI>
        <obo:IAO_0000115>A TSSA protein that is part of Trypanosoma cruzi</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi TSSA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010085 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010085">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010085</metadata:prefixIRI>
        <obo:IAO_0000115>A CDPK1 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii CDPK1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010086 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010086">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010086</metadata:prefixIRI>
        <obo:IAO_0000115>A CDPK6 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii CDPK6</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010087 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010087">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010087</metadata:prefixIRI>
        <obo:IAO_0000115>A ROP18 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii ROP18</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010088 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010088">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010088</metadata:prefixIRI>
        <obo:IAO_0000115>A CST2 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii CST2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010089 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010089">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010089</metadata:prefixIRI>
        <obo:IAO_0000115>A CyP protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii CyP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010091 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010091">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010091</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA1 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010092 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010092">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010092</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA16 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA16</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010093">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010093</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA17 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA17</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010094 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010094">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010094</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA24 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA24</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010095 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010095">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010095</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA23 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA23</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010096">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010096</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA25 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA25</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010097">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010097</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA41 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA41</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010098 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010098">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010098</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA6 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA6</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010099">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010099</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA7 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA7</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010100</metadata:prefixIRI>
        <obo:IAO_0000115>A GRA8 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii GRA8</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010101">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010101</metadata:prefixIRI>
        <obo:IAO_0000115>A hsp70 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii hsp70</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010102 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010102">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010102</metadata:prefixIRI>
        <obo:IAO_0000115>A ISP3 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii ISP3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010103">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010103</metadata:prefixIRI>
        <obo:IAO_0000115>A MIC1 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii MIC1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010104">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010104</metadata:prefixIRI>
        <obo:IAO_0000115>A MIC11 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii MIC11</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010105 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010105">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010105</metadata:prefixIRI>
        <obo:IAO_0000115>A MIC13 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii MIC13</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010106 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010106">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010106</metadata:prefixIRI>
        <obo:IAO_0000115>A MIC4 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii MIC4</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010107 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010107">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010107</metadata:prefixIRI>
        <obo:IAO_0000115>A MIC6 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii MIC6</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010108 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010108">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010108</metadata:prefixIRI>
        <obo:IAO_0000115>A MIC8 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii MIC8</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010109 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010109">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010109</metadata:prefixIRI>
        <obo:IAO_0000115>A PGAM2 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii PGAM2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010110 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010110">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010110</metadata:prefixIRI>
        <obo:IAO_0000115>A RACK1 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii RACK1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010111 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010111">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010111</metadata:prefixIRI>
        <obo:IAO_0000115>A ROP16 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii ROP16</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010112 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010112">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010112</metadata:prefixIRI>
        <obo:IAO_0000115>A ROP17 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii ROP17</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010114 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010114">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010114</metadata:prefixIRI>
        <obo:IAO_0000115>A PLP1 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii PLP1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010115 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010115">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010115</metadata:prefixIRI>
        <obo:IAO_0000115>A ROP38 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii ROP38</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010116 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010116">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010116</metadata:prefixIRI>
        <obo:IAO_0000115>A ROP8 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii ROP8</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010118 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010118">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010118</metadata:prefixIRI>
        <obo:IAO_0000115>A ROP2 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii ROP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010119</metadata:prefixIRI>
        <obo:IAO_0000115>A SAG2 protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii SAG2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010120</metadata:prefixIRI>
        <obo:IAO_0000115>A SAG5B protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii SAG5B</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010121">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010121</metadata:prefixIRI>
        <obo:IAO_0000115>A SAG5C protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii SAG5C</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010122 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010122">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010122</metadata:prefixIRI>
        <obo:IAO_0000115>A TgADF protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii TgADF</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010123 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010123">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010123</metadata:prefixIRI>
        <obo:IAO_0000115>A TgNTPase-II protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii TgNTPase-II</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010124 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010124">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010124</metadata:prefixIRI>
        <obo:IAO_0000115>A TgPF protein that is part of Toxoplasma gondii</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii TgPF</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010125 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010125">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1279"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010125</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1279"/>
        <obo:VO_0005438>76</obo:VO_0005438>
        <obo:VO_0010151>40213225</obo:VO_0010151>
        <obo:VO_1000000>Staphylococcus bacteriophage lysate</obo:VO_1000000>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus bacteriophage lysate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010126 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010126">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010126</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the species of the host used for a study.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host species variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010127 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010127">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010127</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0010162"/>
        <rdfs:label>obsolete Historical diphtheria and tetanus toxoids and acellular pertussis, poliovirus, Haemophilus b conjugate and hepatitis B (recombinant) vaccine.</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010128 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010128">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001178"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003495"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010128</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:IAO_0000118>influenza, live, intranasal, quadrivalent</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, live, intranasal, quadrivalent vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010129 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010129">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010129</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the host&apos;s participation in a disease state (i.e. healthy, or diabetic).</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:32516066</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host disease state variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010130 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010130">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010130</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the biological sex of the host</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host sex variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010131 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010131">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010131</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the age of the host</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:32347787</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host age variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010132 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010132">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010132</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the presence of another developing organism in an animal host</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:34082643</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host pregnancy variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010133 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010133">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000647"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010133</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, seasonal vaccine, quadrivalent, adjuvanted, 0.5mL dose, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010134 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010134">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010134</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing host quality&apos;s that leads to a wore outcome to vaccination or pathogen disease state.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:32516066</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host comorbidity variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010135 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010135">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000753"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1273"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010135</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1273"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
        <obo:VO_0005438>303</obo:VO_0005438>
        <obo:VO_1000000>Respiratory syncytial virus (RSV), vaccine, recombinant, protein subunit RSV prefusion F, adjuvant reconstituted, 0.5 mL, preservative free</obo:VO_1000000>
        <obo:VO_1000001>RSV, recombinant, protein subunit RSVpreF, adjuvant reconstituted, 0.5 mL, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Respiratory syncytial virus (RSV), vaccine, recombinant, protein subunit RSV prefusion F, adjuvant reconstituted, 0.5 mL, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010136 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010136">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000754"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010136</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>305</obo:VO_0005438>
        <obo:VO_1000000>Respiratory syncytial virus (RSV), vaccine, bivalent, protein subunit RSV prefusion F, diluent reconstituted, 0.5 mL, preservative free</obo:VO_1000000>
        <obo:VO_1000001>RSV, bivalent, protein subunit RSVpreF, diluent reconstituted, 0.5 mL, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Respiratory syncytial virus (RSV), vaccine, bivalent, protein subunit RSV prefusion F, diluent reconstituted, 0.5 mL, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010137 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010137">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000755"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010137</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>306</obo:VO_0005438>
        <obo:VO_1000000>Respiratory syncytial virus (RSV) monoclonal antibody, IgG1κ, (nirsevimab-alip), 0.5 mL, neonates and children to 24 months</obo:VO_1000000>
        <obo:VO_1000001>RSV, mAb, nirsevimab-alip, 0.5 mL, neonate to 24 months</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0010138 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010139 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010140 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010141 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010142 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010144 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010144</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <obo:VO_0005438>313</obo:VO_0005438>
        <obo:VO_1000000>SARS-COV-2 (COVID-19) vaccine, subunit, recombinant spike protein-nanoparticle+Matrix-M1 Adjuvant, preservative free, 5 mcg/0.5 mL dose</obo:VO_1000000>
        <obo:VO_1000001>COVID-19, subunit, rS-nanoparticle, adjuvanted, PF, 5 mcg/0.5 mL</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS-COV-2 (COVID-19) vaccine, subunit, recombinant spike protein-nanoparticle+Matrix-M1 Adjuvant, preservative free, 5 mcg/0.5 mL dose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010145 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010145">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010145</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the prior immungenic memory a host has against a specific pathogen</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:32668444</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host pathogen exposure variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010146">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000561"/>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010146</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000807"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        <obo:VO_0005438>316</obo:VO_0005438>
        <obo:VO_1000000>Meningococcal polysaccharide (groups A, C, Y, W) tetanus toxoid conjugate, meningococcal B recombinant vaccine, 0.5mL, preservative free</obo:VO_1000000>
        <obo:VO_1000001>Meningococcal polysaccharide (MenACWY-TT conjugate), (MenB), PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Meningococcal polysaccharide (groups A, C, Y, W) tetanus toxoid conjugate, meningococcal B recombinant vaccine, 0.5mL, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010147 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010147">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010147</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0005438>317</obo:VO_0005438>
        <obo:VO_1000000>Chikungunya, live attenuated vaccine, 0.5 mL, preservative free</obo:VO_1000000>
        <obo:VO_1000001>Chikungunya live attenuated vaccine, 0.5 mL, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chikungunya, live attenuated vaccine, 0.5 mL, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010148 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010148">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000014"/>
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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>318</obo:VO_0005438>
        <obo:VO_1000000>Anthrax vaccine, adsorbed, adjuvanted, post-exposure prophylaxis</obo:VO_1000000>
        <obo:VO_1000001>Anthrax, post-exposure prophylaxis</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Anthrax vaccine, adsorbed, adjuvanted, post-exposure prophylaxis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010149 -->

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        <obo:IAO_0000115>An information content entity that specify no vaccine adminstered.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx</obo:IAO_0000119>
        <obo:VO_0005438>998</obo:VO_0005438>
        <obo:VO_1000000>no vaccine administered</obo:VO_1000000>
        <obo:VO_1000001>no vaccine administered</obo:VO_1000001>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>no vaccine administered</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010150">
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        <obo:IAO_0000115>A record of missing knowledge indicating that vaccine or immune globulin is unknown.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>unknown vaccine or immune globulin</obo:IAO_0000118>
        <obo:IAO_0000119>https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx</obo:IAO_0000119>
        <obo:VO_0005438>999</obo:VO_0005438>
        <obo:VO_0010151>40213263</obo:VO_0010151>
        <obo:VO_1000000>unknown vaccine or immune globulin</obo:VO_1000000>
        <obo:VO_1000001>unknown</obo:VO_1000001>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>record of unknown vaccine or immune globulin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010153 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0005438>521</obo:VO_0005438>
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        <obo:VO_1000000>SARS-COV-2 (COVID-19) vaccine SP, protein-based, adjuvanted, B.1.351 strain (VidPrevtyn Beta), Sanofi-GSK</obo:VO_1000000>
        <obo:VO_1000001>COVID-19 SP, protein-based, adjuvanted (VidPrevtyn Beta), Sanofi-GSK</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS-COV-2 (COVID-19) vaccine SP, protein-based, adjuvanted, B.1.351 strain (VidPrevtyn Beta), Sanofi-GSK</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010154 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_1000000>hepatitis B vaccine, adult dosage</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B vaccine, adult dosage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010155 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010156 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010157 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010158 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010159 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010166 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010170 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010171 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010172 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010173 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010174 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010175 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010176 -->

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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        <obo:VO_0005438>111</obo:VO_0005438>
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        <obo:VO_1000000>Influenza, live, trivalent, intranasal</obo:VO_1000000>
        <obo:VO_1000001>Influenza, live, trivalent, intranasal</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, live, trivalent, intranasal</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010177 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus vaccine, H5N1, A/Vietnam/1203/2004 (national stockpile)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010178 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010178</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        <obo:VO_0005438>135</obo:VO_0005438>
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        <obo:VO_1000000>Influenza, high-dose, split virus, trivalent, injectable, preservative free</obo:VO_1000000>
        <obo:VO_1000001>Influenza, high-dose, trivalent, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, high-dose, split virus, trivalent, injectable, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010179 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010179">
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010179</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0005438>140</obo:VO_0005438>
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        <obo:VO_1000000>Influenza, split virus, trivalent, injectable, preservative free</obo:VO_1000000>
        <obo:VO_1000001>Influenza, split virus, trivalent, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, split virus, trivalent, injectable, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010180 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_1000000>Influenza, split virus, trivalent, injectable, contains preservative</obo:VO_1000000>
        <obo:VO_1000001>Influenza, split virus, trivalent, preservative</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, split virus, trivalent, injectable, contains preservative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010181 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>seasonal influenza, intradermal, preservative free</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010182 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, live, quadrivalent, intranasal</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010183 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, split virus, quadrivalent, injectable, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010184 -->

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        <obo:VO_1000000>Influenza, Madin Darby Canine Kidney, subunit, trivalent, injectable, preservative free</obo:VO_1000000>
        <obo:VO_1000001>Influenza, MDCK, trivalent, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, Madin Darby Canine Kidney, subunit, trivalent, injectable, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010185">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010185</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>155</obo:VO_0005438>
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        <obo:VO_1000000>Influenza, recombinant, trivalent, injectable, preservative free</obo:VO_1000000>
        <obo:VO_1000001>Influenza, recombinant, trivalent, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, recombinant, trivalent, injectable, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010186 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010186">
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            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010186</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>158</obo:VO_0005438>
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        <obo:VO_1000000>Influenza, split virus, quadrivalent, injectable, contains preservative</obo:VO_1000000>
        <obo:VO_1000001>Influenza, split virus, quadrivalent, preservative</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, split virus, quadrivalent, injectable, contains preservative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010187 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010187">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010187</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
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        <obo:VO_0005438>160</obo:VO_0005438>
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        <obo:VO_1000000>Influenza A monovalent (H5N1), adjuvanted, National stockpile 2013</obo:VO_1000000>
        <obo:VO_1000001>Influenza A monovalent (H5N1), ADJUVANTED-2013</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A monovalent (H5N1), adjuvanted, National stockpile 2013</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010188 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010188">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010188</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>168</obo:VO_0005438>
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        <obo:VO_1000000>Influenza, adjuvanted, inactivated, trivalent, injectable, preservative free</obo:VO_1000000>
        <obo:VO_1000001>Influenza, adjuvanted, trivalent, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, adjuvanted, inactivated, trivalent, injectable, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010189 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0005438>171</obo:VO_0005438>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, Madin Darby Canine Kidney, subunit, quadrivalent, injectable, preservative free</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010190 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, recombinant, quadrivalent, injectable, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010191 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010191">
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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_1000000>influenza, Southern Hemisphere, unspecified formulation</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, Southern Hemisphere, unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010192 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0005438>197</obo:VO_0005438>
        <obo:VO_0010151>724896</obo:VO_0010151>
        <obo:VO_1000000>Influenza, high-dose, split virus, quadrivalent, injectable, preservative free</obo:VO_1000000>
        <obo:VO_1000001>Influenza, high-dose, quadrivalent, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, high-dose, split virus, quadrivalent, injectable, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010193 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010193">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010193</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0005438>200</obo:VO_0005438>
        <obo:VO_0010151>724897</obo:VO_0010151>
        <obo:VO_1000000>influenza, seasonal, Southern Hemisphere, quadrivalent, pediatric 0.25mL dose, preservative free</obo:VO_1000000>
        <obo:VO_1000001>influenza, Southern Hemisphere, pediatric, preservative free</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, seasonal, Southern Hemisphere, quadrivalent, pediatric 0.25mL dose, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010194">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010194</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        <obo:VO_0005438>201</obo:VO_0005438>
        <obo:VO_0010151>724898</obo:VO_0010151>
        <obo:VO_1000000>influenza, seasonal, Southern Hemisphere, quadrivalent, 0.5mL dose, no preservative</obo:VO_1000000>
        <obo:VO_1000001>influenza, Southern Hemisphere, preservative free</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, seasonal, Southern Hemisphere, quadrivalent, 0.5mL dose, no preservative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010195 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010195">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010195</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        <obo:VO_0005438>202</obo:VO_0005438>
        <obo:VO_0010151>724899</obo:VO_0010151>
        <obo:VO_1000000>influenza, seasonal, Southern Hemisphere, quadrivalent, 0.5mL dose, with preservative</obo:VO_1000000>
        <obo:VO_1000001>influenza, Southern Hemisphere, quadrivalent, with preservative</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, seasonal, Southern Hemisphere, quadrivalent, 0.5mL dose, with preservative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010196 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010196">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001176"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010196</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>205</obo:VO_0005438>
        <obo:VO_0010151>724902</obo:VO_0010151>
        <obo:VO_1000000>Influenza, adjuvanted, inactivated, quadrivalent, injectable, preservative free</obo:VO_1000000>
        <obo:VO_1000001>Influenza, adjuvanted, quadrivalent, PF</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Influenza, adjuvanted, inactivated, quadrivalent, injectable, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010197 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010197">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010197</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>231</obo:VO_0005438>
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        <obo:VO_1000000>influenza, seasonal, Southern Hemisphere, high-dose, quadrivalent, 0.7mL dose, preservative free</obo:VO_1000000>
        <obo:VO_1000001>influenza, Southern Hemisphere, high-dose, quadrivalent</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, seasonal, Southern Hemisphere, high-dose, quadrivalent, 0.7mL dose, preservative free</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010198 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010198</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>320</obo:VO_0005438>
        <obo:VO_1000000>Influenza, Madin Darby Canine Kidney, subunit, trivalent, injectable, contains preservative</obo:VO_1000000>
        <obo:VO_1000001>Influenza, MDCK, trivalent, preservative</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza, Madin Darby Canine Kidney, subunit, trivalent, injectable, contains preservative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010199 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_1000000>Japanese Encephalitis Vaccine SC</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese Encephalitis vaccine SC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010200 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010201 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010202 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0010203 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal oligosaccharide (groups A, C, Y and W-135) diphtheria toxoid conjugate vaccine (MCV4O)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010204 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010205 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010206 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010207 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010208 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010209 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010210 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010211 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010212 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010213 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010214 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0005438>304</obo:VO_0005438>
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        <obo:VO_1000001>Respiratory syncytial virus (RSV), unspecified</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Respiratory syncytial virus (RSV), unspecified</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010215 -->

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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010215</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_1000000>Respiratory syncytial virus (RSV) vaccine, unspecified</obo:VO_1000000>
        <obo:VO_1000001>Respiratory syncytial virus (RSV) vaccine, unspecified</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Respiratory syncytial virus (RSV) vaccine, unspecified</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010216 -->

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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010216</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_1000000>Respiratory syncytial virus (RSV) monoclonal antibody (MAB), unspecified</obo:VO_1000000>
        <obo:VO_1000001>Respiratory syncytial virus (RSV) MAB, unspecified</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Respiratory syncytial virus (RSV) monoclonal antibody (MAB), unspecified</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010217 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_1000000>rotavirus, live, pentavalent vaccine</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rotavirus, live, pentavalent vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010218 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rotavirus, live, monovalent vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010219 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal vaccine, unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010220 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>tetanus toxoid, adsorbed</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010221 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
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        <obo:VO_0005438>139</obo:VO_0005438>
        <obo:VO_0010151>40213229</obo:VO_0010151>
        <obo:VO_1000000>Td(adult) unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>Td(adult) unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Td(adult) unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010222 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010222</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0005438>101</obo:VO_0005438>
        <obo:VO_0010151>40213246</obo:VO_0010151>
        <obo:VO_1000000>typhoid Vi capsular polysaccharide vaccine</obo:VO_1000000>
        <obo:VO_1000001>typhoid, ViCPs</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>typhoid Vi capsular polysaccharide vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010223 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0005438>187</obo:VO_0005438>
        <obo:VO_0010151>706103</obo:VO_0010151>
        <obo:VO_1000000>zoster vaccine recombinant</obo:VO_1000000>
        <obo:VO_1000001>zoster recombinant</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>zoster vaccine recombinant</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010224">
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            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010224</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_1000000>zoster vaccine, unspecified formulation</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>zoster vaccine, unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010225 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010225</metadata:prefixIRI>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_0005438>172</obo:VO_0005438>
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        <obo:VO_1000000>cholera, WC-rBS</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>cholera, WC-rBS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010226 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <obo:VO_1000000>yellow fever vaccine live</obo:VO_1000000>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>yellow fever vaccine live</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010227 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010228 -->

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        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>yellow fever vaccine, unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010229">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010229</metadata:prefixIRI>
        <obo:IAO_0000115>An information content entity that specifies the CVX code that will not be used to avoid confusion with code 999.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>RESERVED - do not use</obo:IAO_0000118>
        <obo:IAO_0000119>https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx</obo:IAO_0000119>
        <obo:VO_0005438>99</obo:VO_0005438>
        <obo:VO_1000000>RESERVED - do not use</obo:VO_1000000>
        <obo:VO_1000001>RESERVED - do not use</obo:VO_1000001>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>reserved cvx code for not using</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010230 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010230">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCIT_C85994"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010230</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>TST-OT tine test</obo:IAO_0000118>
        <obo:VO_0005438>95</obo:VO_0005438>
        <obo:VO_0010151>40213238</obo:VO_0010151>
        <obo:VO_1000000>tuberculin skin test; old tuberculin, multipuncture device</obo:VO_1000000>
        <obo:VO_1000001>TST-OT tine test</obo:VO_1000001>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>tuberculin skin test; old tuberculin, multipuncture device</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010231 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010231">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCIT_C85994"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010231</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>TST-PPD intradermal</obo:IAO_0000118>
        <obo:VO_0005438>96</obo:VO_0005438>
        <obo:VO_0010151>40213239</obo:VO_0010151>
        <obo:VO_1000000>tuberculin skin test; purified protein derivative solution, intradermal</obo:VO_1000000>
        <obo:VO_1000001>TST-PPD intradermal</obo:VO_1000001>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>tuberculin skin test; purified protein derivative solution, intradermal</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010232">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCIT_C85994"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010232</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>TST-PPD tine test</obo:IAO_0000118>
        <obo:VO_0005438>97</obo:VO_0005438>
        <obo:VO_0010151>40213240</obo:VO_0010151>
        <obo:VO_1000000>tuberculin skin test; purified protein derivative, multipuncture device</obo:VO_1000000>
        <obo:VO_1000001>TST-PPD tine test</obo:VO_1000001>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>tuberculin skin test; purified protein derivative, multipuncture device</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010233 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010233">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCIT_C85994"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010233</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>TST, unspecified formulation</obo:IAO_0000118>
        <obo:VO_0005438>98</obo:VO_0005438>
        <obo:VO_1000000>tuberculin skin test; unspecified formulation</obo:VO_1000000>
        <obo:VO_1000001>TST, unspecified formulation</obo:VO_1000001>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>tuberculin skin test; unspecified formulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010234">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010234</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the lineage (breed, ethnicity) of the animal host</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:35469999</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host lineage variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010235 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010235">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010235</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the interval between vaccination and pathogen challenge</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:34328699</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccination-challenge interval variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010236">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010236</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the interval between the vaccination and pathogen challenge start</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:34328699</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>intevention interval variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010237 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010237">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010237</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the interval between the pathogen challenge start and end</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:34328699</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>challenge-killing interval variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010238 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010238">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010238</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the administration route of the pathogen challenge</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:34328699</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>challenge admistration route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010239 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010239">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010239</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the planned process used for the sacrifice</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:34328699</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>sacrifice process variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010240 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010240">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010240</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the presence of host adverse events from the vaccination process.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:34153517</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host adverse event variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010241</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the measurement used for an assay</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>assay mesurement variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010242</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the timepoint a biological sample was taken after vaccination</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>assay sample endpoint variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010243 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010243">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010243</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the assay type (ELISA, microarray) etc.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>assay type variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010244</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the programs used to analyze an assay</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>assay analysis tool version variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010245">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010245</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the tissue or source of sample used for an assay.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>assay sample source variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010246 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010246">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010246</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the assay platform used (Nanopore,) etc.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>assay platform variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010247 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010247">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010247</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the species or type of the pathogen</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>pathogen variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010248 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010248">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010248</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the lineage of pathogen strain (incljuding presence or absence of virulence factors)</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24259431</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>pathogen strain variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010249 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010249">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010249</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the presence of an attenuation process (killed microbe) on a pathogen challenge</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>pathogen attenuation variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010250">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010250</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the host vaccination frequency etc.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:29485622</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host vaccination frequency variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010251 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010251">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010251</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the vaccination route etc.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24259431</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccination route variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010252 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010252">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010252</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing dose representing the vaccination </obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:34328699</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccination dose variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010253 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010253">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010253</metadata:prefixIRI>
        <obo:IAO_0000115>A variable represting the number of occurences a vaccination was administered</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24259431</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccination frequency variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010254 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010254">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010254</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the interval between multiple vaccinations.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24259431</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccination interval variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010255</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the vaccine target (pathogen, disease) etc.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24259431</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccine target variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010256 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010256">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010256</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the vaccine antigen (SARS-CoV-2 protein, whole organism) etc.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24259431</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccine antigen variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010257 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010257">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010257</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the vaccine adjuvant (silver) etc.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24259431</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccine adjuvant variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010258 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010258">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010258</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the vaccine vector (DNA plasmid, viral vector) etc.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24259431</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccine vector variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010259 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010259">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010259</metadata:prefixIRI>
        <obo:IAO_0000115>A variable representing the vaccine preservative </obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:24259431</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccine preservative variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010260 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010260">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010288"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010260</metadata:prefixIRI>
        <obo:IAO_0000115>A study design variable that is used in a vaccine study.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccine study design variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010261">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0500000"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010261</metadata:prefixIRI>
        <obo:IAO_0000115>A study design that is about a vaccine study.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccine study design</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010262 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010262">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010261"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010262</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine study design that is about the host response to a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>host response to vaccine study design</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010263 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010263">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010261"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010263</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine study design that is about the vaccine challenge to a host.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>vaccine challenge study design</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010264 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010264">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010264</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that records the presence of a disease process in a host during the implementation of a vaccine study.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>host disease state datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010265 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010265">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001194"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010265</metadata:prefixIRI>
        <obo:IAO_0000115>A biological sex datum that records the biological sex of the target of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>host sex datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010266 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010266">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010266</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records  the age of thost.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>host age datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010267 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010267">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010267</metadata:prefixIRI>
        <obo:IAO_0000115>A measurement datum that records to involvement of the host of the pregnancy process.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>host pregnancy datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010268 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010268">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010268</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the quality of the host to have a comorbidity.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>host comorbidity datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010269 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010269">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010269</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that  records the presence of a prior infection or immune memory to a pathogen.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>host pathogen exposure datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010270 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010270">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010270</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that  records the interval between the vaccine challenge and the sacrifice of the organism during a vaccine challenge.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>challenge-killing interval datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010271 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010271">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010271</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the route of a pathogen challenge occurs in.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>challenge admistration route datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010272">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010272</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the method of sacrifice (i.e. killing). </obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>sacrifice process datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010273">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010273</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the presence or abasence of adverse event in a host in response of some vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>host adverse event  to vaccine datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010274 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010274">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010274</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the measurement of an assay.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>assay mesurement datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010275 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010275">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010275</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the time point between the start of a first intervention in a planned process and the measurment of a sample.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>assay  measurement sample  interval</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010276 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010276">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010276</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the type of assay used.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>assay type datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010277 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010277">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010277</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the version of an analysis tool (software) used for an assay.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>assay analysis tool version datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010278">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010278</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the type of platform used for an assay.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>assay platform datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010279 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010279">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010279</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the utilization of an attenaution process on a pathogen.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>pathogen attenuation datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010280">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010280</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the number of occurences the host was vaccinated as part of the vaccination process.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccination frequency datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010281">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010281</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the interval between vaccinations of a host.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccination interval datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010282 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010282">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010282</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the intended target of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine target datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010283 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010283">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010283</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the vaccine vector of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine vector datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010284 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010284">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010284</metadata:prefixIRI>
        <obo:IAO_0000115>A measurment datum that records the vaccine preservative of a vaccine.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>data item</oboInOwl:inSubset>
        <rdfs:label>vaccine preservative datum</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010285 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010285">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010285</metadata:prefixIRI>
        <obo:IAO_0000115>An assay that measures the survival rate of organisms exposed to a pathogen.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>vaccine challenge survival assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010286 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010286">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010286</metadata:prefixIRI>
        <obo:IAO_0000115>An assay that measures the gut adhesion of a pathogen within an organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>pathogen gut adhesion assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010287 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010287">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000070"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010287</metadata:prefixIRI>
        <obo:IAO_0000115>An assay that measures the titer of antibodies that neturalize a pathogen within an organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>assay</oboInOwl:inSubset>
        <rdfs:label>viral neutralization titer assay</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010288 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010288">
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000750"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000751"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010288</metadata:prefixIRI>
        <obo:IAO_0000115>A directive information entity that is part of a study design. It can be eithor independent variables whose values are selected to determine its relationship to an observed phenomenon (the dependent variable) or dependent variables that are studied and expected to change when the independent variable varies.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>study design variable</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010289 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010289">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000053"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0004888"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf>
            <owl:Restriction>
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    <!-- http://purl.obolibrary.org/obo/VO_0010290 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010291 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010292 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010293 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010294 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010295 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010296 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010297 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010298 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010299 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010300 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010301 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010302 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010303 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010304 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010305 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010306 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010307 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010308 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010309 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010310 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010311 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010312 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010313 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010314 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010315 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010316 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010317 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010318 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010319 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010320 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010321 -->

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        <rdfs:label>Bordetella Pertussis Filamentous Haemagglutinin Antigen vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010322 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010323 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010324 -->

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                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000642"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0018849"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_102793"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010324</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_102793"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus (H5N1) antigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010325 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010325">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0018868"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000646"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000712"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010325</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis A virus strain CR 326F antigen, inactivated vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010326 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010326">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000669"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003801"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000669"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010326</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella zoster virus glycoprotein E vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010327 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010327">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0003150"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0017677"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003150"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010327</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B virus subtype ADW2 HBsAg surface protein antigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010328 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010328">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000669"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0003802"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000669"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010326"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010328</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8536"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varicella zoster virus glycoprotein E, recombinant vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010329 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010329">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0003501"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010329"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003501"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010299"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010329</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Victoria/361/2011 (H3N2) antigen vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010330 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010330">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010330</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that inject the material (such as vaccines, allergens) directly into a tumor.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intratumoral route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010331 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010331">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000574"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010331</metadata:prefixIRI>
        <obo:IAO_0000115>A route of administration that inject the material (such as vaccines, allergens) directly into a lesion or into the skin.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>intralesional route</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007655"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010332</metadata:prefixIRI>
        <obo:IAO_0000115>Antigen that is only expressed by tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>tumor-specific antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010333 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010333">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007655"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010333</metadata:prefixIRI>
        <obo:IAO_0000115>Antigen that is overexpressed by tumor cells.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>tumor-associated antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010334">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000753"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010334</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Respiratory Syncytial Virus Vaccine</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1273"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>ABRYSVO</obo:VO_0003099>
        <obo:VO_0003160>Active immunization of pregnant individuals at 32 through 36 weeks gestational age for the prevention of lower respiratory tract disease (LRTD) and severe LRTD caused by respiratory syncytial virus (RSV) in infants from birth through 6 months of age.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/171482/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125768</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ABRYSVO (STN 125768) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010335 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010335">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000753"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010335</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Respiratory Syncytial Virus Vaccine</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1273"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>ABRYSVO</obo:VO_0003099>
        <obo:VO_0003160>Active immunization for the prevention of lower respiratory tract disease (LRTD) caused by respiratory syncytial virus (RSV) in individuals 60 years of age and older.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/168889/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125769</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>ABRYSVO (STN 125769) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010336 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010336</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Influenza Vaccine</obo:IAO_0000118>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>Afluria Quadrivalent Southern Hemisphere</obo:VO_0003099>
        <obo:VO_0003160>Active immunization against influenza disease caused by influenza A subtype viruses and type B viruses contained in the vaccine. Afluria Quadrivalent is approved for use in persons 6 months of age and older.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/145736/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>BL 125254</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AFLURIA QUADRIVALENT SOUTHERN HEMISPHERE vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010337 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010337</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Influenza Virus Vaccine (Trivalent, Types A and B)</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010394"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>Afluria Southern Hemisphere</obo:VO_0003099>
        <obo:VO_0003160>Active immunization against influenza disease cause by influenza virus subtypes A and type B present in the vaccine. Afluria is approved for use in persons 6 months of age and older.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/145737/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>BL 125254</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AFLURIA SOUTHERN HEMISPHERE vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010338 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010338">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010338</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Respiratory Syncytial Virus Vaccine, Adjuvanted</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1273"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>AREXVY</obo:VO_0003099>
        <obo:VO_0003160>AREXVY is a vaccine indicated for active immunization for the prevention of lower respiratory tract disease (LRTD) caused by respiratory syncytial virus (RSV) in:
individuals 60 years of age and older;
individuals 50 through 59 years of age who are at increased risk for LRTD caused by RSV</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/167805/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125775</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AREXVY vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010339 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010339</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Influenza A (H5N1) Monovalent Vaccine, Adjuvanted</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000580"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>AUDENZ</obo:VO_0003099>
        <obo:VO_0003160>AUDENZ is an inactivated vaccine indicated for active immunization for the prevention of disease caused by the influenza A virus H5N1 subtype contained in the vaccine.
AUDENZ is approved for use in persons 6 months of age and older at increased risk of exposure to the influenza A virus H5N1 subtype contained in the vaccine.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/135020/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125692</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_102793"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>AUDENZ vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010340 -->

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        </rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010340</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Pneumococcal 21-valent Conjugate Vaccine</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010394"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0040084"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>CAPVAXIVE</obo:VO_0003099>
        <obo:VO_0003160>CAPVAXIVE is indicated for:
Active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 3, 6A, 7F, 8, 9N, 10A, 11A, 12F, 15A,15B, 15C, 16F, 17F, 19A, 20A, 22F, 23A, 23B, 24F, 31, 33F, and 35B inindividuals 18 years of age and older.
Active immunization for the prevention of pneumonia caused by S. pneumoniaeserotypes 3, 6A, 7F, 8, 9N, 10A, 11A, 12F, 15A, 15C, 16F, 17F, 19A, 20A, 22F,23A, 23B, 24F, 31, 33F, and 35B in individuals 18 years of age and older.
The indication for the prevention of pneumonia caused by S. pneumoniae serotypes 3, 6A, 7F, 8, 9N, 10A, 11A, 12F, 15A, 15C, 16F, 17F, 19A, 20A, 22F, 23A, 23B, 24F, 31, 33F, and 35B is approved under accelerated approval based on immune responses as measured by opsonophagocytic activity (OPA) [see Clinical Studies (14.1)]. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/179426/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125814</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1313"/>
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        <rdfs:label>CAPVAXIVE vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010341 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Anthrax Vaccine Adsorbed, Adjuvanted</obo:IAO_0000118>
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        <obo:VO_0003099>CYFENDUS</obo:VO_0003099>
        <obo:VO_0003160>For post-exposure prophylaxis of disease following suspected or confirmed exposure to Bacillus anthracis in persons 18 through 65 years of age when administered in conjunction with recommended antibacterial drugs</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/170445/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125761</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1392"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>CYFENDUS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010342 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Dengue Tetravalent Vaccine, Live</obo:IAO_0000118>
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        <obo:VO_0003161>https://www.fda.gov/media/124379/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125682</obo:VO_0003162>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DENGVAXIA vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010343 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Ebola Zaire Vaccine, Live</obo:IAO_0000118>
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        <obo:VO_0003099>ERVEBO</obo:VO_0003099>
        <obo:VO_0003160>ERVEBO is a vaccine indicated for For the prevention of disease caused by Zaire ebolavirus in individuals 12 months of age and older.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/133748/download?attachment</obo:VO_0003161>
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        <rdfs:label>ERVEBO vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010344 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <rdfs:label>FLUAD QUADRIVALENT vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010345 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010346 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010347 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010348 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010349 -->

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        <obo:VO_0003160>For active immunization of persons 18 through 64 years of age at increased risk of exposure to the H5N1 influenza virus subtype contained in the vaccine</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/74534/download?attachment</obo:VO_0003161>
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    <!-- http://purl.obolibrary.org/obo/VO_0010351 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Smallpox and Monkeypox Vaccine, Live, Non-Replicating</obo:IAO_0000118>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000137"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3292"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8736"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>JYNNEOS</obo:VO_0003099>
        <obo:VO_0003160>For prevention of smallpox and monkeypox disease in adults 18 years of age and older determined to be at high risk for smallpox or monkeypox infection.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/131078/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125678</obo:VO_0003162>
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        <rdfs:label>JYNNEOS vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010352 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Respiratory Syncytial Virus Vaccine</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003099>MRESVIA</obo:VO_0003099>
        <obo:VO_0003160>MRESVIA is a vaccine indicated for active immunization for the prevention of lower respiratory tract disease (LRTD) caused by respiratory syncytial virus (RSV) in individuals 60 years of age and older.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/179005/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125796</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12814"/>
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        <rdfs:label>MRESVIA vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010353 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Meningococcal (Groups A, C, Y, and W-135) Vaccine</obo:IAO_0000118>
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        <obo:VO_0003099>MenQuadfi</obo:VO_0003099>
        <obo:VO_0003160>MenQuadfi is a vaccine indicated for active immunization for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, W, and Y. MenQuadfi is approved for use in individuals 2 years of age and older.MenQuadfi does not prevent N. meningitidis serogroup B disease.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/137306/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125701</obo:VO_0003162>
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        <rdfs:label>MenQuadfi vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010354 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <obo:VO_0003099>PENBRAYA</obo:VO_0003099>
        <obo:VO_0003160>PENBRAYA is indicated for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroups A, B, C, W, and Y. PENBRAYA is approved for use in individuals 10 through 25 years of age.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/173223/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125770</obo:VO_0003162>
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        <rdfs:label>PENBRAYA vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010355 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010356 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010357 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010358 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010359 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Varicella Virus Vaccine Live</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>VARIVAX</obo:VO_0003099>
        <obo:VO_0003160>VARIVAX is a vaccine indicated for active immunization for the prevention of varicella in individuals 12 months of age and older.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/76008/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>BL 103552</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varivax (Frozen) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010364 -->

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        <rdfs:subClassOf>
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Varicella Virus Vaccine Live</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003099>VARIVAX</obo:VO_0003099>
        <obo:VO_0003160>VARIVAX is a vaccine indicated for active immunization for the prevention of varicella in individuals 12 months of age and older.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/media/76000/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>BL 103552</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Varivax (Refrigerator) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010365 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:IAO_0000118>Zoster Vaccine, Live, (Oka/Merck)</obo:IAO_0000118>
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        <obo:VO_0003161>https://www.fda.gov/media/119879/download?attachment</obo:VO_0003161>
        <obo:VO_0003162>125123</obo:VO_0003162>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Zostavax (Frozen) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010366 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <obo:VO_0003162>125123</obo:VO_0003162>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10335"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Zostavax (Refrigerator Stable) vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010367 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>(Squeezable Tube Presentation) - ROTARIX vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010368 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010369 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010393 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010394 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010395 -->

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        <obo:IAO_0000115>A period typically associated with a higher incidence of influenza virus infections, characterized by the increased circulation of flu viruses in a population.</obo:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/VO_0010415 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010433 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010434 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010435 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010436 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010440 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010441 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010442 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010443 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010444 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010445 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010446 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010447 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010449 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010450 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010454 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0050175"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010454</metadata:prefixIRI>
        <obo:IAO_0000115>Tick-borne Encephalitis Virus (TBEV) vaccine with license for human use.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0050175"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human tick-borne encephalitis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010455 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010455">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000763"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000763"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1498"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010455</metadata:prefixIRI>
        <obo:IAO_0000115>Vibrio cholerae vaccine with license for human use.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1498"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human vibrio cholerae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010456">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000123"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000123"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_9682"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11089"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010456</metadata:prefixIRI>
        <obo:IAO_0000115>yellow fever virus vaccine with license for human use.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9682"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11089"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human yellow fever virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010457 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010457">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0010415"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010457</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>seasonal licensed human influenza virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010460 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010460">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2697049"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010460</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>organism</oboInOwl:inSubset>
        <rdfs:label>SARS Coronavirus 2 XBB.1.5</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010461 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010461">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000287"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010461</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced innate immune response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010462 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010462">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000135"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010462</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine-induced response</oboInOwl:inSubset>
        <rdfs:label>vaccine-induced cell-mediated immune response</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010463 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010463">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPMI_0000446"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010463</metadata:prefixIRI>
        <obo:IAO_0000115>An immune biomarker that indicates a humoral immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>humoral immune marker</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010464 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010464">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OPMI_0000446"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010464</metadata:prefixIRI>
        <obo:IAO_0000115>An immune biomarker that indicates a cell-mediated immune response.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>cell-mediated immune marker</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010465 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010465">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000857"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010465</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22437237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>correlated profile of immune protection based on population coverage</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010466 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010466">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010465"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010466</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsey N Anderson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>specific correlate of protection</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:22437237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>specific correlate of immune protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010467 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010467">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010465"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010467</metadata:prefixIRI>
        <obo:IAO_0000115>Correlated profile of immune protection that reliably predicts vaccine efficacy across settings different from those studied in an efficacy trial.</obo:IAO_0000115>
        <obo:IAO_0000117>Jeremy Zucker</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>bCoP</obo:IAO_0000118>
        <obo:IAO_0000118>bridging correlate of protection</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:22437237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>general correlate of immune protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010468 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010468">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000857"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010468</metadata:prefixIRI>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:22437237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>correlated profile of immune protection based on statistical level</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010469 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010469">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010468"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010469</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsey N Anderson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>cocorrelate</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:22437237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>cocorrelate of immune protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010470 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010470">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010468"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010470</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsey N Anderson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>relative correlate</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:22437237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>relative correlate of immune protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010471 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010471">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010468"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010471</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsey N Anderson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>absolute correlate</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:22437237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>absolute correlate of immune protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010472 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010472">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000857"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010472</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsey N Anderson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>surrogate of protection</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:22437237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>correlated profile of immune protection based on causality</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010473 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010473">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010472"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010473</metadata:prefixIRI>
        <obo:IAO_0000115>Correlated profile of immune protection that is not a mechanistic causal agent of protection, but is still predictive of vaccine efficacy.</obo:IAO_0000115>
        <obo:IAO_0000117>Jeremy Zucker</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsey N Anderson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>nCoP</obo:IAO_0000118>
        <obo:IAO_0000118>nonmechanistic correlate of immune protection</obo:IAO_0000118>
        <obo:IAO_0000119>PMID:22437237</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/603</obo:IAO_0000233>
        <oboInOwl:inSubset>process profile</oboInOwl:inSubset>
        <rdfs:label>nonmechanistic correlate of immune protection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010474 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010474">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010472"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010474</metadata:prefixIRI>
        <obo:IAO_0000115>Correlated profile of immune protection that is mechanistically and causally responsible for protection.</obo:IAO_0000115>
        <obo:IAO_0000117>Jeremy Zucker</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Lindsey N Anderson</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>mCoP</obo:IAO_0000118>
        <obo:IAO_0000118>mechanistic correlate of protection</obo:IAO_0000118>
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    <!-- http://purl.obolibrary.org/obo/VO_0010475 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010476 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Diphtheria, Tetanus, and acellular Pertussis vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010477 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010478 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010479 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010480 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010481 -->

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        <rdfs:label>licensed human leprosy vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010482 -->

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        <rdfs:label>licensed human Yersinia pestis vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010483 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010484 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010485 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010486 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010487 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010488 -->

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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_38568"/>
        <obo:VO_0005438>64</obo:VO_0005438>
        <obo:VO_0010151>40213165</obo:VO_0010151>
        <obo:VO_1000000>leishmaniasis vaccine</obo:VO_1000000>
        <obo:VO_1000001>leishmaniasis</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human Leishmania vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010489 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010489</metadata:prefixIRI>
        <obo:IAO_0000115>malaria vaccine is licensed for use in humans.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0005438>67</obo:VO_0005438>
        <obo:VO_0010151>40213169</obo:VO_0010151>
        <obo:VO_1000000>malaria vaccine</obo:VO_1000000>
        <obo:VO_1000001>malaria</obo:VO_1000001>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human malaria vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010490 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010490</metadata:prefixIRI>
        <obo:IAO_0000115>Melanoma vaccine that is licensed for use in humans.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0005438>68</obo:VO_0005438>
        <obo:VO_0010151>40213171</obo:VO_0010151>
        <obo:VO_1000000>melanoma vaccine</obo:VO_1000000>
        <obo:VO_1000001>melanoma</obo:VO_1000001>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>licensed human melanoma vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010491 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010491</metadata:prefixIRI>
        <obo:IAO_0000115>Parainfluenza 3 virus vaccine is licensed for use in humans.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0005438>69</obo:VO_0005438>
        <obo:VO_0010151>40213194</obo:VO_0010151>
        <obo:VO_1000000>parainfluenza-3 virus vaccine</obo:VO_1000000>
        <obo:VO_1000001>parainfluenza-3</obo:VO_1000001>
        <rdfs:label>licensed human Parainfluenza 3 virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010632 -->

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        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>country</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010633 -->

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        <obo:IAO_0000115>USA is a country that exists in north America.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>site</oboInOwl:inSubset>
        <rdfs:label>USA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010637 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010637</metadata:prefixIRI>
        <obo:IAO_0000115>A viral vaccine that protects against infection with Rubella virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>rubella vaccine</obo:IAO_0000118>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rubella virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010702 -->

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        <obo:IAO_0000115>A vaccine regulation for vaccine safety.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>process</oboInOwl:inSubset>
        <rdfs:label>vaccine saftey regulation</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010704 -->

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        <obo:IAO_0000115>A vaccine regulatory process that is for vaccine regulatory agent to review vaccine license application from vaccine producer.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <rdfs:label>review of vaccine license application</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010705 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010705</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=554</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=555</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=557</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=761</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>554</obo:VO_0001818>
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        <obo:VO_0003099>Actacel</obo:VO_0003099>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Actacel vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010706 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010706</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Avaxim</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=559</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000891"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_7507"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>559</obo:VO_0001818>
        <obo:VO_0003099>Avaxim</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avaxim vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010707 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010707</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Avaxim - Pediatric</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=560</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000891"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_7507"/>
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        <obo:VO_0001818>560</obo:VO_0001818>
        <obo:VO_0003099>Avaxim - Pediatric</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Avaxim - Pediatric vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010708 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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        <obo:VO_0001818>3231</obo:VO_0001818>
        <obo:VO_0003099>BCG Vaccine (Freeze-Dried)</obo:VO_0003099>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>BCG vaccine (Freeze-Dried) (by Sanofi Pasteur)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010709 -->

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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010709</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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        <obo:VO_0001818>563</obo:VO_0001818>
        <obo:VO_0003099>DT Polio Adsorbed</obo:VO_0003099>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DT Polio Adsorbed vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010710 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010710">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000944"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010710</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0001818>567</obo:VO_0001818>
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        <obo:VO_0003099>Dukoral</obo:VO_0003099>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dukoral vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010711 -->

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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000644"/>
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                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015392"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010711</metadata:prefixIRI>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=323</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm110102.htm</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0004913"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010393"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>323</obo:VO_0001818>
        <obo:VO_0003099>ENGERIX-B</obo:VO_0003099>
        <obo:VO_0003160>ENGERIX-B is a vaccine indicated for immunization against infection caused by all known subtypes of hepatitis B virus.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM224503.pdf</obo:VO_0003161>
        <obo:VO_0003162>103239</obo:VO_0003162>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Engerix-B vaccine</rdfs:label>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010712</metadata:prefixIRI>
        <obo:IAO_0000115>A Measles-Rubella vaccine that is live attenuated and manufactured by GlaxoSmithKline Biologicals.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=568</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=569</obo:IAO_0000119>
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        <obo:VO_0001818>568</obo:VO_0001818>
        <obo:VO_0001818>569</obo:VO_0001818>
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        <rdfs:label>Eolarix vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010713 -->

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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010713</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=570</obo:IAO_0000119>
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        <obo:VO_0001818>570</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Epaxal vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010714 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010714</metadata:prefixIRI>
        <obo:IAO_0000116>todo: assign parent
immunogen: TBE</obo:IAO_0000116>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0001818>742</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0010715 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010722 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0010723 -->

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                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000695"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019418"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010723</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0003049"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/VO_0000913"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>Liquid Pedvax HIB</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Liquid Pedvax HIB vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010724 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000714"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010444"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000531"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010724</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=598</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/VO_0000913"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>598</obo:VO_0001818>
        <obo:VO_0003099>Meningitec</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Meningitec vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010725 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010725">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010444"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000531"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010725</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=599</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/VO_0000913"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>599</obo:VO_0001818>
        <obo:VO_0003099>Meningococcal Polysaccharide Vaccine, Groups A &amp; C, Menomune A/C</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal polysaccharide vaccine, Groups A &amp; C, Menomune A/C</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010726 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010726">
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010726</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=600</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>600</obo:VO_0001818>
        <obo:VO_0003099>Menjugate</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Menjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010727 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010727">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010727</metadata:prefixIRI>
        <obo:IAO_0000116>Menomune A/C/Y/W-135</obo:IAO_0000116>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/688"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000072"/>
        <rdfs:comment>Trade Name: Menomune A/C/Y/W-135</rdfs:comment>
        <rdfs:label>obsolete Menomune A/C/Y/W-135 vaccine</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010728 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010728">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010728</metadata:prefixIRI>
        <obo:IAO_0000115>A live attenuated V. cholerae vaccine that is manufactured by Berna Biotech, Ltd. This vaccine uses the V. Cholera strain CVD 103-HGR.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Mutacol</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=780</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_2877"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000939"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1498"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>780</obo:VO_0001818>
        <obo:VO_0003099>Mutacol</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Trade Name: Mutacol</rdfs:comment>
        <rdfs:label>Mutacol vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010729 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010729">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010444"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            <owl:Restriction>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010729</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Neisvac-C</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=603</obo:IAO_0000119>
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        <obo:VO_0001818>603</obo:VO_0001818>
        <obo:VO_0003099>Neisvac-C</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neisvac-C vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010730 -->

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            <owl:Restriction>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010730</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=604</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=605</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=607</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=608</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=766</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16842"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0000930"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17076"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_7507"/>
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        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/VO_0000915"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>604</obo:VO_0001818>
        <obo:VO_0001818>605</obo:VO_0001818>
        <obo:VO_0001818>607</obo:VO_0001818>
        <obo:VO_0001818>608</obo:VO_0001818>
        <obo:VO_0001818>766</obo:VO_0001818>
        <obo:VO_0003099>Pediacel</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0000741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Pediacel vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010731 -->

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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010731</metadata:prefixIRI>
        <obo:IAO_0000115>A polyvalent pneumococcal vaccine used to protectsagainst serious infection (e.g., meningitis, bacteria in the blood) due to Streptococcus pneumoniae, and it is manufactured by Sanofi Pasteur.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>PNEUMO (PNU-IMUNE)</obo:IAO_0000118>
        <obo:IAO_0000118>Pnu-Imune</obo:IAO_0000118>
        <obo:IAO_0000118>Pnu-Imune 23</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=615</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.webmd.com/drugs/2/drug-5547/pnu-imune-injection/details</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>615</obo:VO_0001818>
        <obo:VO_0003099>Pneumo 23</obo:VO_0003099>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>Generic Name: pneumococcal vaccine polyvalent (Intramuscular route, Subcutaneous route)</rdfs:comment>
        <rdfs:label>Pneumo 23</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010732 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:comment>Trade Name: Pneumovax 23</rdfs:comment>
        <rdfs:label>obsolete Pneumovax 23 (Canada)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010733 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010733</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.prevnar13.com/</obo:IAO_0000119>
        <rdfs:comment>Trade Name: Prevnar</rdfs:comment>
        <rdfs:label>obsolete Prevnar (Canada)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010734 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=626</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=770</obo:IAO_0000119>
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        <obo:VO_0001818>770</obo:VO_0001818>
        <obo:VO_0003099>Quadracel</obo:VO_0003099>
        <obo:VO_0003160>Active immunization against diphtheria, tetanus, pertussis and poliomyelitis. A single dose of Quadracel is approved as a fifth dose in the diphtheria, tetanus, pertussis (DTaP) vaccination series, and as a fourth or fifth dose in the inactivated poliovirus (IPV) vaccination series in children 4 through 6 years of age whose previous DTaP vaccine doses have been with Pentacel, DAPTACEL, and/or VAXELIS.</obo:VO_0003160>
        <obo:VO_0003161>https://www.fda.gov/vaccines-blood-biologics/vaccines/quadracel</obo:VO_0003161>
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        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010738</metadata:prefixIRI>
        <obo:IAO_0000116>todo: assign parent
immunogen: ROT</obo:IAO_0000116>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010745 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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        <rdfs:label>Vaqta vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0010746 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010747 -->

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        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0010748 -->

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        <obo:VO_0001818>644</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vivaxim vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010749 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010749">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003353"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17716"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_2877"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000531"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000915"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000304"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0000687"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010749</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Vivotif (Canada)</obo:IAO_0000118>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000864"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17716"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/CHEBI_2877"/>
        <obo:VO_0000531 rdf:resource="http://purl.obolibrary.org/obo/VO_0000915"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003099>Vivotif</obo:VO_0003099>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vivotif vaccine (Canada)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010751 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010751">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010751</metadata:prefixIRI>
        <obo:IAO_0000115>a protein from a bacterium</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>bacterium protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010752 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010752">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010751"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010752</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>G+ bacterium protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010753 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010753">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010751"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010753</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>G- bacterium protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010754 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010754">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010754</metadata:prefixIRI>
        <obo:IAO_0000115>a protein from a virus</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010755 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010755">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010755</metadata:prefixIRI>
        <obo:IAO_0000115>a protein from a parasite</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>parasite protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010756 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010756">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PR_000000001"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010756</metadata:prefixIRI>
        <obo:IAO_0000115>a protein from fungus</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>fungus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010757 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010757">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010757</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Bacillus anthracis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010758 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010758">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010758</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Brucella protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010759 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010759">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010759</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010760 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010760">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010760</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010761 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010761">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010761</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Ebola virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010762 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010762">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010762</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Clostridium botulinum protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010763 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010763">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010763</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Lassa Fever Virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010764 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010764">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010764</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Variola virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010765 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010765">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010765</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Campylobacter jejuni protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010766 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010766">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010766</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Escherichia coli protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010767 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010767">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010767</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Human Immunodeficiency Virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010768 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010768">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010768</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Hantavirus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010769 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010769">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010769</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Marburg Virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010770 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010770">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010770</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010771 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010771">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010771</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium spp. protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010772 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010772">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010772</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010773 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010773">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010773</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Coxiella burnetii protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010774 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010774">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010774</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>VEE Virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010775 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010775">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010775</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Clostridium tetani protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010776 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010776">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010776</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Salmonella spp. protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010777 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010777">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010777</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Shigella protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010778 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010778">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010778</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010779 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010779">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010779</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pneumoniae protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010780 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010780">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010780</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Hepatitis A virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010781 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010781">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010781</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010782 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010782">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010782</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Influenza virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010783 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010783">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010783</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010784 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010784">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010784</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Measles virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010785 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010785">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010785</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Mumps virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010786 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010786">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010786</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010787 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010787">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010787</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Poliovirus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010788 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010788">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010788</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Rabies virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010789 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010789">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010789</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Rotavirus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010790 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010790">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010790</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Rubella virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010791 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010791">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010791</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Yellow fever virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010792 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010792">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010792</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Varicella-zoster virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010793 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010793">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010793</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Tick-borne Encephalitis Virus (TBEV) protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010794 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010794">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010794</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila pneumoniae protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010795 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010795">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010795</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010796 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010796">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010796</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Yersinia pseudotuberculosis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010797 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010797">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010797</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Bovine Leukemia virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010798 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010798">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010798</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Corynebacterium diphtheriae protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010799 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010799">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010799</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Porcine circovirus 2 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010800 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010800">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010800</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Pseudorabies virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010801 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010801">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010801</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Classical swine fever virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010802 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010802">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010802</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010803 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010803">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010803</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>West Nile virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010804 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010804">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010804</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s disease virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010805 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010805">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010805</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Newcastle disease virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010806 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010806">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010806</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Feline leukemia virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010807 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010807">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010807</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Canine parvovirus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010808 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010808">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010808</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Canine coronavirus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010809 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010809">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010809</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Canine distemper virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010810 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010810">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010810</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Infectious Hematopoietic Necrosis Virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010811 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010811">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010811</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Lawsonia intracellularis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010812 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010812">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010812</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Porphyromonas gulae protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010813 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010813">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010813</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Yersinia ruckeri protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010814 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010814">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010814</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Aeromonas salmonicida protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010815 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010815">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010815</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Vibrio anguillarum (Listonella anguillarum) protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010816 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010816">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010816</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Streptococcus equi protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010817 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010817">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010817</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010818 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010818">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010818</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma synoviae protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010819 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010819">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010819</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma gallisepticum protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010820 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010820">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010820</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Bordetella avium protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010821 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010821">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010821</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Actinobacillus pleuropneumoniae protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010822 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010822">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010822</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Eimeria spp. protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010823 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010823">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010822"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010823</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Eimeria tenella protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010824 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010824">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010824</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Theileria parva protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010825 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010825">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010825</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Theileria annulata protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010826 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010826">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010826</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010827 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010827">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010827</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Babesia bovis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010828 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010828">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010828</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Neospora caninum protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010829 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010829">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005477"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010829</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Giardia duodenalis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010830 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010830">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010830</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Sarcocystis neurona protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010831 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010831">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010831</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Babesia canis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010832 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010832">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015478"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010832</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010833 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010833">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010822"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010833</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Eimeria maxima protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010834 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010834">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010834</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus type 1 and 2 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010835 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010835">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015478"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010835</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania major protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010836 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010836">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015478"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010836</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania infantum protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010837 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010837">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015478"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010837</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania amazonensis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010838 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010838">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010838</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma cruzi protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010839 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010839">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010839</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila psittaci protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010840 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010840">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010840</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Burkholderia pseudomallei protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010841 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010841">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010841</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Western equine encephalomyelitis virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010842 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010842">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010842</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Cryptosporidium parvum protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010843 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010843">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010843</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Hendra virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010844 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010844">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010844</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Dengue Virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010845 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010845">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010845</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Nipah virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010846 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010846">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010846</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Rickettsia spp protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010847 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010847">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010847</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010848 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010848">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010848</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Vibrio cholerae protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010849 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010849">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010849</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Rift Valley Fever virus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010850 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010850">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010754"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010850</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>SARS-CoV protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010851 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010851">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010851</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Yersinia enterocolitica protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010852 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010852">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010852</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Entamoeba histolytica protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010853 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010853">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010756"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010853</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Coccidioides spp. protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010854 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010854">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010854</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma brucei protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010855 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010855">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010753"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010855</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010856 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010856">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010856</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>IMMUNOGENICITY: Induces antigen-specific Th1 immune response, as indicated by the specific induction of serum IgG2a, but not IgG1, antibodies and by the secretion of IFN-alpha but not IL-4, by the Cu/Zn SOD-stimulated splenocytes. Has been used for vaccine development [PubMed: 10816475][PubMed: 11953393][PubMed: 12933826].    

MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replacement exhibited much greater susceptibility to killing by exogenous O(2)(-) than the parental 2308 strain, supporting a role for SodC in protecting this bacterium from O(2)(-) stress. The B abortus sodC mutant was much more sensitive to killing by cultured resident peritoneal macrophages from C57BL6J mice than 2308, and its attenuation in cultured murine macrophages was enhanced when these phagocytes were treated with gamma interferon. The attenuation of the B abortus sodC mutant in both resting and IFN-gamma-activated macrophages was alleviated in the presence of the NADPH oxidase inhibitor apocynin. Consistently, the B abortus sodC mutant also displayed significant attenuation in infected C57BL6J mice compared to the parental strain. These findings suggest that SodC protects B abortus 2308 from the respiratory burst of host macrophages [PubMed: 15845493].</rdfs:comment>
        <rdfs:label>SodC from B. abortus strain 2308</rdfs:label>
        <rdfs:seeAlso>VIOLILN Protegen ID: 3; NCBI Protein GI: 83269434; NCBI Protein Accession: YP_418725.1; NCBITaxon: 234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010857 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010857">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010757"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010857</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Lef from B. anthracis str. A2012</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 5; NCBI Gene GI: 1158731; NCBI Protein GI: 40646957; NCBI Protein Accession: AAR88323.1; NCBITaxon: 32630</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010858 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010858">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010858</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>EBOV GP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 10; NCBI Gene GI: 955190</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010859 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010859">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010859</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>EBOV NP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 11; NCBI Gene GI: 955194; NCBI Protein GI: 22789223; NCBI Protein Accession: NP_690580; NCBITaxon: 186539</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010860 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010860">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010860</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>VP24 from Reston ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 12; NCBI Gene GI: 955193; NCBI Protein GI: 22789228; NCBI Protein Accession: NP_690586; NCBITaxon: 186539</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010861 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010861">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010861</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>VP40 from Reston ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 13; NCBI Gene GI: 955192; NCBI Protein GI: 22789225; NCBI Protein Accession: NP_690582; NCBITaxon: 186539</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010862 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010862">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010862</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>VP30 from Reston ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 14; NCBI Gene GI: 955196; NCBI Protein GI: 22789227; NCBI Protein Accession: NP_690585; NCBITaxon: 186539</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010863 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010863">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010863</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>VP35 from Reston ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 15; NCBI Gene GI: 955189; NCBI Protein GI: 22789224; NCBI Protein Accession: NP_690581; NCBITaxon: 186539</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010864 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010864">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010864</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>VP35 expressed from alphavirus replicons induced a protective immune response in C57BL/6 mice when challenged with Ebola virus Zaire [PubMed: 11485406].</rdfs:comment>
        <rdfs:label>VP35 from Zaire ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 16; NCBI Gene GI: 911827; NCBI Protein GI: 10313992; NCBI Protein Accession: NP_066244; NCBITaxon: 186538</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010865 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010865">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010865</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant Tbp1 and Tbp2 proteins were expressed from Escherichia coli and antisera were raised to the purified proteins. In a passive model of bacteraemia, infant rats were protected from challenge with Hib after transfer of anti-rTbp2 antiserum, but not after anti-rTbp1 antiserum [PubMed: 8830248].</rdfs:comment>
        <rdfs:label>Tbp2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 277; NCBI Gene GI: 3430457; NCBI Protein GI: 68249580; NCBI Protein Accession: YP_248692; NCBITaxon: 281310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010866 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010866">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010866</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>VP24 expressed from alphavirus replicons induced a protective immune response in BALB/c mice when challenged with Ebola virus Zaire [PubMed: 11485406].</rdfs:comment>
        <rdfs:label>VP24 from Zaire ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 17; NCBI Gene GI: 911828; NCBI Protein GI: 10313998; NCBI Protein Accession: NP_066250; NCBITaxon: 186538</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010867 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010867">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010867</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>VP30 expressed from alphavirus replicons induced a protective immune response in BALB/c mice when challenged with Ebola virus Zaire [PubMed: 11485406].</rdfs:comment>
        <rdfs:label>VP30 from Zaire ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 18; NCBI Gene GI: 911826; NCBI Protein GI: 10313997; NCBI Protein Accession: NP_066249; NCBITaxon: 186538</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010868 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010868">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010868</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination of BALB/c or C57BL/6 mice with eVLPs, composed of the EBOV glycoprotein and matrix viral protein (VP)40 with a lipid membrane, in conjunction with QS-21 adjuvant resulted in mixed IgG subclass responses, a Th1-like memory cytokine response, and protection from lethal EBOV challenge [PubMed: 16002721].

VP40 expressed from alphavirus replicons induced a protective immune response in BALB/c mice when challenged with Ebola virus Zaire [PubMed: 11485406].</rdfs:comment>
        <rdfs:label>VP40 from Zaire ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 19; NCBI Gene GI: 911825; NCBI Protein GI: 10313993; NCBI Protein Accession: NP_066245; NCBITaxon: 186538</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010869 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010869">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010763"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010869</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>HLA-A*0201 mice immunized with either GPC(42-50) from LASVsSgp2 glycoprotein or GPC(60-68) were protected against challenge with a recombinant vaccinia virus that expressed LASV GPC [PubMed: 16912286].</rdfs:comment>
        <rdfs:label>LASVsSgp2 glycoprotein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 20; NCBI Gene GI: 956585; NCBI Protein GI: 23343511; NCBI Protein Accession: NP_694870; NCBITaxon: 11620</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010870 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010870">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010870</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Caf1 from Y. pestis biovar Microtus str. 91001</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 23; NCBI Gene GI: 2767670; NCBI Protein GI: 45478667; NCBI Protein Accession: NP_995523; NCBITaxon: 229193</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010871 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010871">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010764"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010871</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>It has previously been shown that a DNA subunit vaccine (4pox) based on four orthopoxvirus immunogens (L1R, B5R, A27L and A33R) can produce protective immunity against lethal orthopoxvirus challenges in mice and nonhuman primates. the immunogenicity of an L1R construct to which a tissue plasminogen activator signal sequence was placed in frame with the full-length L1R gene was tested. When the tPA-L1R construct was substituted for the unmodified L1R gene in the 4pox vaccine, given as a prime and single boost, animals were better protected from lethal challenge with vaccinia virus (VACV) [PubMed: 18485547].</rdfs:comment>
        <rdfs:label>L1R from Monkeypox virus Zaire-96-I-16</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 28; NCBI Gene GI: 928938; NCBI Protein GI: 17974998; NCBI Protein Accession: NP_536512; NCBITaxon: 619591</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010872 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010872">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010757"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010872</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>PagA from B. anthracis str. Ames Ancestor</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 32; NCBI Gene GI: 2820165; NCBI Protein GI: 47566476; NCBI Protein Accession: NC_007322.2</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010873 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010873">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010757"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010873</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Lef from B. anthracis str. Ames Ancestor</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 38; NCBI Gene GI: 2820148; NCBI Protein GI: 47566484; NCBI Protein Accession: NC_007322.2</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010874 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010874">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010874</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>MAb BA5 protected animals against plague, neutralized the Y. pestis type III secretion pathway and promoted opsonophagocytic clearance of bacteria in blood. LcrV residues 196-225 were necessary and sufficient for MAb BA5 binding.  These results identify LcrV residues 196-225 as a linear epitope that is recognized by the murine immune system to confer plague protection [PubMed: 20005318].</rdfs:comment>
        <rdfs:label>LcrV from y. pestis CO92</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 44; NCBI Gene GI: 1172676; NCBI Protein GI: 16082719; NCBI Protein Accession: NP_395165; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010875 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010875">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010875</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>An LcrV variant lacking amino acid residues 271 to 300 (rV10) elicited immune responses that protected mice against a lethal challenge with Y. pestis [PubMed: 16041032].</rdfs:comment>
        <rdfs:label>LcrV from Y. pestis KIM 10</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 45; NCBI Gene GI: 1149310; NCBI Protein GI: 31795491; NCBI Protein Accession: NP_857946; NCBITaxon: 187410</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010876 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010876">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010876</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>V antigen</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 46; NCBI Gene GI: 4118094</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010877 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010877">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010877</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study evaluated the humoral immune response of mice that survived lethal Y. pestis aerosol challenge after antibiotic treatment. Results indicated that one of the predominant antibody response of mice surviving pneumonic plague after treatment with antibiotics was to pla [PubMed: 10085037].</rdfs:comment>
        <rdfs:label>Pla</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 48; NCBI Gene GI: 1172643; NCBI Protein GI: 16082686; NCBI Protein Accession: NP_395233; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010878 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010878">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010878</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The type III secretion apparatus encoded on the low-calcium response (LCR) virulence plasmid, pCD1 in strain KIM5, of Y. pestis is a conserved virulence mechanism that is absolutely required for virulence of Y. pestis. YscF is a surface localized protein required both to secrete Yops and to translocate toxins into eukaryotic cells. YscF polymerization is possibly required for a YscF needle to puncture eukaryotic cell membranes. It is also likely that YscF and its homologs function to provide a base that a translocon complex is built upon, or that YscF builds a conduit from the bacterium to the eukaryotic membrane - this suggestion seems more likely given that other proteins such as YopB, YopD, and LcrV are also required for translocation into eukaryotic cells. YscF is thought to be a surface-expressed protein in Y. pestis and is required for virulence. YscF has been found to function as a protective antigen against experimental plague infection [PubMed: 15978133].</rdfs:comment>
        <rdfs:label>YopD from Y. pestis CO92</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 49; NCBI Gene GI: 1172673; NCBI Protein GI: 16082716; NCBI Protein Accession: NP_395162; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010879 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010879">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010879</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #3, gatA) was found to be protective.  Three of the clones (CP #1) elicited protection that was statistically higher than the unvaccinated control, which has high variance [PubMed: 15811648].

Note:  Part of CP #3 also belongs to gatB</rdfs:comment>
        <rdfs:label>GatA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 422; NCBI Protein GI: 62184918; NCBITaxon: 218497</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010880 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010880">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010880</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #3, gatB) was found to be protective.  Three of the clones (CP #1) elicited protection that was statistically higher than the unvaccinated control, which has high variance [PubMed: 15811648].

Note:  Part of CP #3 also belongs to gatA</rdfs:comment>
        <rdfs:label>GatB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 424; NCBI Protein GI: 62147986; NCBITaxon: 218497</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010881 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010881">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010881</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The MOMP (omp1) DNA immunization induced a non-specific and partial protection in OF1 outbred mice fetuses against challenge with C. abortus [PubMed: 12488563].</rdfs:comment>
        <rdfs:label>Omp1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 425; NCBI Protein GI: 40601; NCBITaxon: 83555</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010882 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010882">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010882</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In pregnant mice, the dnaK vaccine induced a non-specific partial protection from abortion after challenge with Chlamydophila abortus [PubMed: 12056482].</rdfs:comment>
        <rdfs:label>DnaK from Chlamydophila abortus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 426; NCBI Protein GI: 26006347; NCBITaxon: 83555</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010883 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010883">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010794"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010883</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The immunogenicity and protective effect of recombinant LcrE protein combined either with Freund&apos;s or Alum adjuvant were investigated in mice. The immunization with both protocols resulted in a significant reduction of the number of viable C. pneumoniae in the lungs after challenge. Results confirm that LcrE induces protective immunity in mice [PubMed: 19451031].</rdfs:comment>
        <rdfs:label>LcrE</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 428; NCBI Gene GI: 895078; NCBI Protein GI: 15618244; NCBI Protein Accession: NP_224529; NCBITaxon: 115713</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010884 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010884">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010794"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010884</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Results of this study showed that intranasal immunization of BALB/c mice with heat-aggregated CopN protein and an Escherichia coli heat-labile toxin (LT) induced a strong immune response.  The immunization induced statistically significant protection against intranasal C. pneumoniae challenge, the level of which correlated with the magnitude of CopN-specific lymphocyte proliferation [PubMed: 16949182].</rdfs:comment>
        <rdfs:label>CopN</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 429; NCBI Protein GI: 33241669; NCBITaxon: 182082</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010885 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010885">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010795"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010885</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0512 showed significant levels of protection when compared to negative control animals.  At 9 days following challenge TC0512 showed a 73% reduction in the number of recoverable Chlamydia compared with vector only immunized controls  [PubMed: 17239501].</rdfs:comment>
        <rdfs:label>TC0512 outer membrane protein, putative</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 430; NCBI Gene GI: 1245872; NCBI Protein GI: 15835130; NCBI Protein Accession: NP_296889; NCBITaxon: 243161</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010886 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010886">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010795"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010886</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0757 showed significant levels of protection when compared to negative control animals [PubMed: 17239501].</rdfs:comment>
        <rdfs:label>TC0757 hypothetical protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 431; NCBI Gene GI: 1246122; NCBI Protein GI: 15835371; NCBI Protein Accession: NP_297130; NCBITaxon: 243161</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010887 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010887">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010795"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010887</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0439 showed significant levels of protection when compared to negative control animals [PubMed: 17239501].</rdfs:comment>
        <rdfs:label>TC0439 adherence factor</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 432; NCBI Gene GI: 1245792; NCBI Protein GI: 15835057; NCBI Protein Accession: NP_296816; NCBITaxon: 243161</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010888 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010888">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010795"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010888</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0767/768 showed significant levels of protection when compared to negative control animals [PubMed: 17239501].</rdfs:comment>
        <rdfs:label>TC0767 hypothetical protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 433; NCBI Gene GI: 1246132; NCBI Protein GI: 15835381; NCBI Protein Accession: NP_297140; NCBITaxon: 243161</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010889 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010889">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010795"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010889</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0767/768 showed significant levels of protection when compared to negative control animals [PubMed: 17239501].</rdfs:comment>
        <rdfs:label>TC0768 hypothetical protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 434; NCBI Gene GI: 1246133; NCBI Protein GI: 15835382; NCBI Protein Accession: NP_297141; NCBITaxon: 243161</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010890 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010890">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010795"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010890</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Female BALB/c mice were immunized with chlamydial major outer membrane protein (MOMP) mixed with cholera toxin and CpG oligodeoxynucleotide adjuvants by either the IN or TCI routes.  Both intranasal and transcutaneous immunization protected mice against respiratory challenge with Chlamydia [PubMed: 16153755].</rdfs:comment>
        <rdfs:label>MOMP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 435; NCBI Protein GI: 1518659; NCBITaxon: 83560</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010891 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010891">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010795"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010891</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection.  Overall, vaccination with DCs transfected with PmpG-1(25-500) exhibited the greatest degree of protective immunity among the four Chlamydia Ags tested [PubMed: 19155509].</rdfs:comment>
        <rdfs:label>PmpG-1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 436; NCBI Gene GI: 1246433; NCBI Protein GI: 15834883; NCBI Protein Accession: NP_296642; NCBITaxon: 243161</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010892 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010892">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010795"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010892</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection.  In addition, RplF was able to engender protective immunity against challenge with C. muridarum [PubMed: 19155509].</rdfs:comment>
        <rdfs:label>RplF</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 437; NCBI Gene GI: 1246168; NCBI Protein GI: 15835415; NCBI Protein Accession: NP_297174; NCBITaxon: 243161</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010893 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010893">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010795"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010893</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection.  In addition, pmpE/F-2 was able to engender protective immunity against challenge with C. muridarum [PubMed: 19155509].</rdfs:comment>
        <rdfs:label>PmpE/F-2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 438; NCBI Gene GI: 1246432; NCBI Protein GI: 15834882; NCBI Protein Accession: NP_296641; NCBITaxon: 243161</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010894 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010894">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010794"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010894</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>IM-ID vaccination with CPn0095 (pknD) generated a response that resulted in moderately, but significantly reduced total C. pneumoniae lung loads as compared to control mice vaccinated with a plasmid expressing a non-Chlamydia ORF (p0.019).  This resulted in the ability of CPN0095 to mediate a moderate, but statistically significant level of protection in an inbred A/J mouse respiratory challenge model [PubMed: 16434129].</rdfs:comment>
        <rdfs:label>PknD</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 439; NCBI Gene GI: 895704; NCBI Protein GI: 161353778; NCBI Protein Accession: NP_224303; NCBITaxon: 115713</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010895 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010895">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010794"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010895</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>M-ID vaccination with fabD generated a response that resulted in moderately, but significantly reduced total C. pneumoniae lung loads as compared to control mice vaccinated with a plasmid expressing a non-Chlamydia ORF (p 0.019). This resulted in the ability of fabD to mediate a moderate, but statistically significant level of protection in an inbred A/J mouse respiratory challenge model [PubMed: 16434129].</rdfs:comment>
        <rdfs:label>FabD</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 440; NCBI Gene GI: 894994; NCBI Protein GI: 15618217; NCBI Protein Accession: NP_224502; NCBITaxon: 115713</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010896 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010896">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010794"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010896</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice vaccinated with candidate gene ssb showed significant reduction of spleen chlamydial loads as compared to nave, non-protected control mice (p 0.048).  This resulted in the ability of ssb to mediate a modest, but significant level of protection in an inbred A/J mouse respiratory challenge model [PubMed: 16434129].</rdfs:comment>
        <rdfs:label>Ssb</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 441; NCBI Gene GI: 894901; NCBI Protein GI: 15618301; NCBI Protein Accession: NP_224586; NCBITaxon: 115713</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010897 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010897">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010801"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010897</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Pigs were subjected to challenge infection with a dose of 1x10(5)TCID(50) (50% tissue culture infective dose) virulent CSFV strain.  At 1 week post challenge infection, all of the yE2-immunized pigs were alive and without symptoms or signs of CSF.  The yeast-expressed E2 protein retains correct immunogenicity and is able to induce a protective immune response against CSFV infection [PubMed: 19625145].

In a seperate study, swine vaccinated with VVR expressing E0 and/or E2 resisted a lethal challenge infection with CSFV. Glycoprotein E0 represents a second determinant for the induction of protective immunity against classical swine fever [PubMed: 7666549].</rdfs:comment>
        <rdfs:label>E2 from Classical swine fever virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 442; NCBI Gene GI: 920146; NCBI Protein GI: 12657942; NCBI Protein Accession: NP_075354; NCBITaxon: 11096</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010898 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010898">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010801"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010898</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Swine vaccinated with VVR expressing E0 and/or E2 resisted a lethal challenge infection with CSFV. Glycoprotein E0 represents a second determinant for the induction of protective immunity against classical swine fever [PubMed: 7666549].</rdfs:comment>
        <rdfs:label>E0</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 443; NCBI Protein GI: 115343287; NCBITaxon: 11096</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010899 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010899">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010801"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010899</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intramuscular vaccination of pigs with immunoaffinity-purified E1 (gp55) in a double water-oil emulsion elicited high titers of neutralizing antibodies between 2 and 4 weeks after vaccination at the lowest dose tested (20 micrograms). The vaccinated pigs were completely protected against intranasal challenge with 100 50% lethal doses of HCV (Classical swine fever virus) strain Brescia [PubMed: 8350404].</rdfs:comment>
        <rdfs:label>Gp55</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 444; NCBI Protein GI: 1763691; NCBITaxon: 11096</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010900 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010900">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010762"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010900</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A single dose of ciBoNT/A1 HP provided equivalent or greater protective immunity, not only against the homologous toxin, but also against two distinct toxin subtypes with significant amino acid divergence in mice when challenged with BoNT/A subtypes /A1, /A2, and /A3 from Clostridium botulinum [PubMed: 19450643].</rdfs:comment>
        <rdfs:label>BoNT/A1 from C. botulinum</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 445; NCBI Protein GI: 241183337; NCBITaxon: 1491</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010901 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010901">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010762"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010901</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Purified FHc was used to vaccinate mice and evaluate their survival against challenge with active botulinum neurotoxin serotype F (BoNT/F).  Mice that received one injection of 5 microg or two injections of &gt;or=0.04 microg of FHc were completely protected [PubMed: 18845829].</rdfs:comment>
        <rdfs:label>FHc</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 446; NCBI Protein GI: 166236883; NCBITaxon: 32630</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010902 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010902">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010762"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010902</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A completely synthetic gene encoding fragment C, a approximately 50-kDa fragment, of botulinum neurotoxin serotype A was constructed from oligonucleotides.  Mice given three subcutaneous vaccinations were protected against an intraperitoneal administration of 10^6 50% lethal doses (ID50) of serotype A toxin [PubMed: 7790092].</rdfs:comment>
        <rdfs:label>BotA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 447; NCBI Protein GI: 733429; NCBITaxon: 32630</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010903 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010903">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010762"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010903</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice and rabbits were immunized with recombinant HCR/A1 (rHCR/A1) from the classical type A-Hall strain (ATCC 3502) (BoNT/A1) and rHCR/E from BoNT serotype E Beluga (BoNT/E(B)).  The protection elicited by rHCR/A1 to BoNT/A1 and BoNT/A2 and by rHCR/E(B) to BoNT/E(A) indicate that immunization with receptor binding domains elicit protection within sub-serotypes of BoNT [PubMed: 16177380].</rdfs:comment>
        <rdfs:label>BoNT/A1 from C. botulinum A str. Hall</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 448; NCBI Gene GI: 5398487; NCBI Protein GI: 153936924; NCBI Protein Accession: YP_001386738; NCBITaxon: 441771</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010904 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010904">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010762"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010904</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The DNA replicon vaccine (pSCARSBHc) encoding the Hc domain of BoNT/B (BHc) induced better responses and protection against BoNT/B mouse challenge than conventional DNA vaccine.  Recombinant SFV particle VRP-BHc protected mice from high-dose BoNT/B challenge [PubMed: 19712769].</rdfs:comment>
        <rdfs:label>BoNT/B</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 449; NCBI Gene GI: 6030102; NCBI Protein GI: 169834607; NCBI Protein Accession: YP_001693307; NCBITaxon: 498213</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010905 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010905">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010762"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010905</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers constructed a replication-incompetent adenovirus encoding a synthesized codon-optimized gene for expression of the heavy chain C-fragment (H(C)50) of botulinum neurotoxin type C (BoNT/C).  After a single dose of 2 x 10^7pfu adenoviral vectors in a mouse model, the animals were completely protected against intraperitoneal challenge with 100 x MLD(50) of active BoNT/C  [PubMed: 17897756].</rdfs:comment>
        <rdfs:label>BoNT/C(Hc50)</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 450; NCBI Protein GI: 217781; NCBI Protein Accession: BAA14235.1; NCBITaxon: 12336</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010906 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010906">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010780"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010906</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A recombinant vaccinia virus containing most of the P1 region of hepatitis A virus (HAV) was constructed bearing epitopes from structural polypeptides VP4, -3 and -2, and the N terminus of VP. Inoculation of tamarin monkeys with the recombinant virus resulted in the development of a specific anti-HAV immune response which was protective against challenge with a virulent strain of HAV [PubMed: 1654376].</rdfs:comment>
        <rdfs:label>HAVgp2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 680; NCBI Gene GI: 1493919; NCBI Protein GI: 9626734; NCBI Protein Accession: NP_041008; NCBITaxon: 12092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010907 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010907">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010907</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following two intragastric immunizations in BALB/c mice, the Yersinia vectors harboring a DNA vaccine encoding BFR (P39) induced antigen-specific serum immunoglobulin and Th1-type responses among splenocytes. The best protection was conferred by a serotype O:9 strain carrying pCIP39, confirming the importance of the P39 T-cell antigen in this mechanism [PubMed: 11895955].</rdfs:comment>
        <rdfs:label>Bfr from B. abortus S19</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 681; NCBI Gene GI: 6326162; NCBI Protein GI: 189022832; NCBI Protein Accession: YP_001932573; NCBITaxon: 430066</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010908 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010908">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010908</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study was designed to evaluate the immunogenicity and the protective efficacy of a divalent fusion DNA vaccine encoding both the Brucella abortus L7/L12 protein (ribosomal protein, rplL) and Omp16 protein (outer membrane lipoprotein). This divalent DNA vaccine induced a significant level of protection against challenge with the virulent B. abortus in BALB/c mice [PubMed: 16622210].</rdfs:comment>
        <rdfs:label>RplL</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 682; NCBI Gene GI: 3788918; NCBI Protein GI: 82700077; NCBI Protein Accession: YP_414651; NCBITaxon: 359391</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010909 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010909">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010775"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010909</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The fragment C of tetanus toxin was amplified from Clostridium tetani DNA by PCR.  Immunization of mice with rTTC resulted in the production of antibodies that were able to protect mice against a challenge with tetanus toxin furthermore, rTTC in vivo appeared to be able to undergo retrograde axonal transport [PubMed: 12075415].</rdfs:comment>
        <rdfs:label>TTC</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 451; NCBI Protein GI: 157829735; NCBITaxon: 1513</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010910 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010910">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010910</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Cynomolgus macaques were immunized with DNA/rAd5 vaccines expressing ZEBOV (GP) and SEBOV glycoprotein (GP) prior to lethal challenge with BEBOV. Vaccinated subjects developed robust, antigen-specific humoral and cellular immune responses against the GP from ZEBOV as well as cellular immunity against BEBOV GP, and immunized macaques were uniformly protected against lethal challenge with BEBOV [PubMed: 20502688].</rdfs:comment>
        <rdfs:label>GP from Zaire ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 452; NCBI Gene GI: 911829; NCBI Protein GI: 10313995; NCBI Protein Accession: NP_066246; NCBITaxon: 186538</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010911 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010911">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010911</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Cynomolgus macaques were immunized with DNA/rAd5 vaccines expressing ZEBOV (GP) and SEBOV glycoprotein (GP) prior to lethal challenge with BEBOV. Vaccinated subjects developed robust, antigen-specific humoral and cellular immune responses against the GP from ZEBOV as well as cellular immunity against BEBOV GP, and immunized macaques were uniformly protected against lethal challenge with BEBOV [PubMed: 20502688].</rdfs:comment>
        <rdfs:label>GP from Sudan ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 453; NCBI Gene GI: 3160774; NCBI Protein GI: 55770812; NCBI Protein Accession: YP_138523; NCBITaxon: 186540</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010912 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010912">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010761"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010912</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Guinea pigs infected with a single intranasal inoculation of HPIV3/EboGP-NP showed no apparent signs of disease yet developed a strong humoral response specific to the EV proteins. When these animals were challenged with an intraperitoneal injection of 10(3) PFU of EV, there were no outward signs of disease, no viremia or detectable EV antigen in the blood, and no evidence of infection in the spleen, liver, and lungs. In contrast, all of the control animals died or developed severe EV disease following challenge [PubMed: 16474134].</rdfs:comment>
        <rdfs:label>NP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 454; NCBI Gene GI: 911830; NCBI Protein GI: 10314000; NCBI Protein Accession: NP_066243; NCBITaxon: 186538</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010913 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010913">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010913</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Ten mice were inoculated subcutaneously, administered booster injections after one month, and challenged with 130 LD(50) of wild type Y. pestis CO92.  The vaccinated animals produced high levels of specific antibodies against YscF as determined by Western blot. The data were statistically significant (P = 0.053 by two-tailed Fisher&apos;s test), suggesting that the YscF protein can provide a protective immune response against lethal plague challenge during subcutaneous plague infection [PubMed: 15939303].</rdfs:comment>
        <rdfs:label>YscF from Y. pestis CO92</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 54; NCBI Gene GI: 1172700; NCBI Protein GI: 16082743; NCBI Protein Accession: NP_395189; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010914">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010914</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The P4 protein is an integral outer membrane protein that has a role in acquiring hemin and nucleosides [PubMed: 1715322 ].</rdfs:comment>
        <rdfs:label>P4 from Haemophilus influenzae</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 100; NCBITaxon: 727</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010915 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010915">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010915</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant P6 (pal) was capable of eliciting a protective antibody response against live H. influenzae type b challenge in a modified infant rat model of bacteremia [PubMed: 9261944].</rdfs:comment>
        <rdfs:label>Pal</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 101; NCBI Gene GI: 3429820; NCBI Protein GI: 68248984; NCBI Protein Accession: YP_248096; NCBITaxon: 281310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010916 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010916">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010916</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>When mice immunized intranasally with recombinant protein corresponding to the C-terminal region of Hap(S) from H. influenzae strains N187, P860295, and TN106 plus mutant cholera toxin CT-E29H were challenged with strain TN106, they were protected against nasopharyngeal colonization [PubMed: 15557618].</rdfs:comment>
        <rdfs:label>Hap from H. influenzae</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 103; Protegen ID: 102; NCBI Protein GI: 21686508; NCBITaxon: 727</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010917 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010917">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010917</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0010916"/>
        <rdfs:label>obsolete Hap from H. influenzae</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 103; NCBITaxon: 727</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010918 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010918">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010918</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>OMP26 was used to immunize rats via intestinal Peyer&apos;s patches, followed by an intratracheal boost. Immunization was found to significantly enhance bacterial clearance following pulmonary challenge with both the homologous NTHI strain and a different NTHI strain [PubMed: 9573117].</rdfs:comment>
        <rdfs:label>Omp26</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 276; NCBI Nucleotide GI: 4574245; NCBI Protein GI: 4574246; NCBI Protein Accession: AAD23967.1; NCBITaxon: 727</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010919 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010919">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010919</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The heterologous prime-boost strategy of live Salmonella vaccine expressing Mycobacterium tuberculosis fusion antigen Age5B-ESAT6 (esxA) from the chromosome followed by a systemic boost of antigen and adjuvant reduced the levels of M. tuberculosis bacteria in the lungs and spleen to the same extent as BCG. Additionally, this vaccination regimen was observed to be statistically equivalent in terms of protection to immunisation with BCG [PubMed: 19755145].</rdfs:comment>
        <rdfs:label>EsxA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 104; NCBI Gene GI: 886209; NCBI Protein GI: 57117165; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010920 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010920">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010920</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>TRAP from P. falciparum</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 138; NCBI Gene GI: 814170; NCBI Protein GI: 124513464; NCBI Protein Accession: XP_001350088; NCBITaxon: 36329</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010921 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010921">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010840"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010921</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>LolC was evaluated as an antigen for a vaccine candidate against B. pseudomallei infection. Nonmembrane regions of the B. pseudomallei protein was expressed and purified from Escherichia coli and then evaluated as a vaccine candidate in an established mouse model of B. pseudomallei infection. When delivered with the monophosphoryl lipid A-trehalose dicorynomycolate adjuvant, the protein stimulated antigen-specific humoral and cellular immune responses. Immunization with the LolC protein domain afforded significant protection against a subsequent challenge with B. pseudomallei.  LolC provided a greater level of protection when it was administered with immune-stimulating complexes complexed with CpG oligodeoxynucleotide 10103. Immunization with LolC also protected against a subsequent challenge with a heterologous strain of B. pseudomallei, demonstrating the potential utility of this protein as a vaccine antigen for melioidosis [PubMed: 17517877].</rdfs:comment>
        <rdfs:label>LolC/E</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 768; NCBI Gene GI: 3093214; NCBI Protein GI: 53719887; NCBI Protein Accession: YP_108873; NCBITaxon: 272560</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010922 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010922">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010840"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010922</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>PotF was evaluated as an antigen for a vaccine candidate against B. pseudomallei infection. Nonmembrane regions of the B. pseudomallei protein was expressed and purified from Escherichia coli and then evaluated as a vaccine candidate in an established mouse model of B. pseudomallei infection. When delivered with the monophosphoryl lipid A-trehalose dicorynomycolate adjuvant, the protein stimulated antigen-specific humoral and cellular immune responses. Immunization with the PotF protein domain afforded significant protection against a subsequent challenge with B. pseudomallei [PubMed: 17517877].</rdfs:comment>
        <rdfs:label>PotF</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 769; NCBI Gene GI: 3095748; NCBI Protein GI: 53721504; NCBI Protein Accession: YP_110489; NCBITaxon: 272560</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010923 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010923">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010923</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>AMA1 from P. falciparum 3D7</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 139; NCBI Gene GI: 810891; NCBI Protein GI: 124804478; NCBI Protein Accession: XP_001348015; NCBITaxon: 36329</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010924 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010924">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010839"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010924</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The ompA codon was adapted to the codon usage in birds, resulting in pcDNA1/MOMP(opt).  Researchers examined the capacity of nebulised or intramuscularly (IM) administered brPEI-pcDNA1/MOMP(opt) to induce a significant protective immune response in SPF turkeys experimentally infected with 10^8 TCID(50) of a virulent Cp. psittaci strain.  Vaccinated groups were significantly protected against Cp. psittaci challenge [PubMed: 20199760].</rdfs:comment>
        <rdfs:label>OmpA from C. psittaci</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 766; NCBI Protein GI: 94467392; NCBITaxon: 83554</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010925 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010925">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010839"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010925</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Plasmid DNA (pcDNA1::MOMP A) expressing the major outer membrane protein (MOMP) of Chlamydophila psittaci genotype A strain 89/1051 has been tested for its ability to induce protective immunity against Cp. psittaci challenge in budgerigars.  DNA immunisation significantly reduced clinical signs, macroscopic lesions, pharyngeal and cloacal excretion as well as chlamydial replication, even in the presence of pre-existing serum antibodies, as compared to the placebo-vaccinated controls [PubMed: 19640395].</rdfs:comment>
        <rdfs:label>MOMP from C. psittaci</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 767; NCBI Nucleotide GI: 144544; NCBI Protein GI: 144545; NCBI Protein Accession: AAA17396.1; NCBITaxon: 83554</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010926 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010926">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010771"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000270"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010926</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000270"/>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 11489167]</rdfs:comment>
        <rdfs:label>ABRA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 137; NCBITaxon: 5835</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010927 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010927">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010927</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>This  gene was originally isolated from a lambda gt11 expression library probed with sera from Brucella-infected sheep. Sequence analysis of the cloned gene revealed the presence of an open reading frame of 158 amino acids encoding a protein of 17.3 kDa [PubMed: 7664168 ]. It was later identified as a cytoplasmic protein lumazine synthase [PubMed: 10482294 ]. This gene can be used for diagnosis [PubMed: 7664168 ] [PubMed: 10482294 ] and vaccine development [PubMed: 11953389 ].</rdfs:comment>
        <rdfs:label>ORF</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 113; NCBI Nucleotide GI: 599653; NCBI Protein GI: 599654; NCBI Protein Accession: CAA86936.1; NCBITaxon: 235</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010928 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010928">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010928</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>B. abortus strain 19 L7/L12</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 114; NCBI Protein GI: 304271</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010929 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010929">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010929</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Guinea pigs were vaccinated with recombinant VEE replicons (packaged into VEE-like particles), inoculated with MBGV, and evaluated for viremia and survival after challenge with typical MGBV disease.  Results indicated that VP35 afforded incomplete protection [PubMed: 9813200 ].</rdfs:comment>
        <rdfs:label>VP35 from Marburg Virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 167; NCBI Gene GI: 920948; NCBI Protein GI: 13489277; NCBI Protein Accession: NP_042026.1; NCBITaxon: 11269</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010930 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010930">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010773"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010930</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The purified recombinant proteins, P1, HspB, and P1-HspB, and whole-cell antigen (WCA) of C. burnetii were used to immunize BALB/c mice.  Protective immunity against Q fever was induced with a recombinant P1 antigen fused with HspB after Coxiella burnetii challenge [PubMed: 16481504 ].</rdfs:comment>
        <rdfs:label>P1 from Coxiella burnetii</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 171; NCBI Protein GI: 30025845; NCBITaxon: 777</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010931 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010931">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010931</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>NP from Zaire ebolavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 172; NCBI Gene GI: 911830; NCBI Protein GI: 10314000; NCBI Protein Accession: NP_066243; NCBITaxon: 186538</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010932 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010932">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010932</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>GP from Marburg Virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 173; NCBI Protein GI: 21702651; NCBITaxon: 186538</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010933 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010933">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010933</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>NP Marburgvirus - Ravn</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 174; NCBI Protein GI: 91177744; NCBITaxon: 378809</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010934 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010934">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010773"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010934</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The purified recombinant proteins, P1, HspB, and P1-HspB, and whole-cell antigen (WCA) of C. burnetii were used to immunize BALB/c mice. Protective immunity against Q fever was induced with a recombinant P1 antigen fused with HspB after Coxiella burnetii challenge [PubMed: 16481504 ].</rdfs:comment>
        <rdfs:label>HspB from Coxiella burnetii</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 175; NCBI Protein GI: 197253489; NCBITaxon: 777</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010935 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010935">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010764"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010935</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice were immunized with recombinant H3L protein to examine H3L-specific antibody responses in greater detail. H3L-immunized mice developed high-titer vaccinia virus-neutralizing antibodies (mean PRNT50 = 1:3,760). Importantly, H3L-immunized mice were subsequently protected against lethal intranasal challenges with 1 or 5 50% lethal doses (LD50) of pathogenic vaccinia virus strain WR, demonstrating the in vivo value of an anti-H3L response. To formally demonstrate that neutralizing anti-H3L antibodies are protective in vivo, we performed anti-H3L serum passive-transfer experiments. Mice receiving H3L-neutralizing antiserum were protected from a lethal challenge with 3 LD50 of vaccinia virus strain WR (5/10 versus 0/10; P &lt; 0.02) [PubMed: 16140750].</rdfs:comment>
        <rdfs:label>H3L</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 62; NCBI Gene GI: 3707557; NCBI Protein GI: 66275898; NCBI Protein Accession: YP_232983; NCBITaxon: 10245</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010936 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010936">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010936</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Ag85A</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 154; NCBITaxon: 1773</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010937 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010937">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010767"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010937</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Env Gp160</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 153; NCBITaxon: 11676</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010938 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010938">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010938</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>StxB2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 225; NCBI Gene GI: 1262010; NCBI Protein GI: 9632507; NCBI Protein Accession: NP_049501; NCBITaxon: 10730</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010939 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010939">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010939</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Omp31</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 231; NCBI Gene GI: 3788834; NCBI Protein GI: 82700421; NCBI Protein Accession: YP_414995; NCBITaxon: 359391</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010940 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010940">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010940</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Tir</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 199; NCBI Gene GI: 960860; NCBI Protein GI: 15804222; NCBI Protein Accession: NP_290261.1; NCBITaxon: 562</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010941 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010941">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010941</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>ETEC also expresses a range of colonisation factor antigens (CFAs), which allow adherence to the mucosal surface and therefore colonisation of the intestine. Some CFAs are sub-divided into coli surface (CS) antigens [PubMed: 17566016].</rdfs:comment>
        <rdfs:label>CS1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 79; NCBI Gene GI: 4188469; NCBI Protein GI: 110643341; NCBI Protein Accession: YP_671071; NCBITaxon: 362663</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010942 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010942">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010942</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>FlaA from C. jejuni NCTC 11168</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 87; NCBI Gene GI: 905631; NCBI Protein GI: 15792662; NCBI Protein Accession: NP_282485.1; NCBITaxon: 197</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010943 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010943">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010943</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>LT is a hetero-oligomeric AB5 type enterotoxin composed of a 27 kDa A subunit with toxic ADP ribosyl transferase activity and a stable noncovalent-linked pentamer of 11.6 kDa B subunits. ETEC infection and colonization of the small intestine, and the production of LT, causes acute diarrhea that can be fatal without intervention [PubMed: 17188785].</rdfs:comment>
        <rdfs:label>EltB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 92; NCBI Protein GI: 157021162; NCBITaxon: 562</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010944 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010944">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010944</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>EHEC strains produce intimin, an outer membrane adhesin encoded by the eae gene located in a chromosomal pathogenicity island termed the locus of enterocyte effacement [PubMed: 17258324].</rdfs:comment>
        <rdfs:label>Eae</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 93; NCBI Gene GI: 960862; NCBI Protein GI: 15804220; NCBI Protein Accession: NP_290259; NCBITaxon: 155864</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010945 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010945">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010945</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>FimH is a protective antigen [PubMed: 9110982]</rdfs:comment>
        <rdfs:label>FimH from E. coli UTI89</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 263; NCBI Gene GI: 3992235; NCBI Protein GI: 91213965; NCBI Protein Accession: YP_543951; NCBITaxon: 364106</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010946 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010946">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010946</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 10710308].</rdfs:comment>
        <rdfs:label>GNA2132</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 264; NCBI Gene GI: 903357; NCBI Protein GI: 15677945; NCBI Protein Accession: NP_275117; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010947 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010947">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010947</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 10710308]</rdfs:comment>
        <rdfs:label>GNA2001</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 265; NCBI Gene GI: 904124; NCBI Protein GI: 15677829; NCBI Protein Accession: NP_274993; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010948 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010948">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010948</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The 39-kDa protein is  immunogenic.</rdfs:comment>
        <rdfs:label>B. melitensis M5 P39</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 110; NCBI Protein GI: 122892474; NCBI Protein Accession: ABM67295</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010949 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010949">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010767"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010949</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A novel primate lentivirus was identified in Mandrillus sphinx. One of the newly isolated SIV strains was intravenously inoculated into two rhesus macaques and resulted in chronic infection. These SIVs do not cluster with SIVmndGB1, the former representative strain of SIVmnd, but form a new, independent lineage. These results indicate that these SIVmnds are a novel type of SIVmnd and have infected Cameroonian mandrills for a long time. To date, M. sphinx is the only primate species other than humans that is naturally infected with two different types of SIV [PubMed: 11522184].</rdfs:comment>
        <rdfs:label>Gag protein from SIV-mnd 2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 98; NCBI Gene GI: 956108; NCBITaxon: 159122</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010950 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010950">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010950</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Gurin vaccination [PubMed: 17671656].</rdfs:comment>
        <rdfs:label>SecA2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 117; NCBI Gene GI: 885594; NCBI Protein GI: 15608958; NCBI Protein Accession: NP_216337; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010951 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010951">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010951</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The 10-kDa culture filtrate protein (CFP-10, esxB) and 6-kDa early secretory antigen of T cells (ESAT-6) are secreted in abundance by Mycobacterium tuberculosis.  Study demonstrated that protective immunity is induced by CFP-10 DNA vaccination in C3H mice as measured by a CFU reduction in the lung and spleen 4 and 8 weeks after challenge with M. tuberculosis [PubMed: 18332205].</rdfs:comment>
        <rdfs:label>EsxB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 121; NCBI Gene GI: 886194; NCBI Protein GI: 15611010; NCBI Protein Accession: NP_218391; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010952 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010952">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010952</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers have developed DNA vaccines expressing M. tuberculosis antigen 85A (Ag85A, fbpA) and cytokine granulocyte macrophage colony stimulating factor (GM-CSF).  The immune strategy of BCG-prime and DNA vaccine boost induced mice to generate efficient immune protection against M. tuberculosis challenge [PubMed: 19450898].</rdfs:comment>
        <rdfs:label>FbpA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 122; NCBI Gene GI: 886132; NCBI Protein GI: 15610940; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010953 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010953">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010953</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>PepA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 123; NCBI Gene GI: 886924; NCBI Protein GI: 15607267; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010954 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010954">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010954</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>PPE18</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 124; NCBI Gene GI: 886073; NCBI Protein GI: 57116841; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010955 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010955">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010955</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>CjaA from C. jejuni RM 1221</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 133; NCBI Gene GI: 3231573; NCBI Protein GI: 57237809; NCBI Protein Accession: YP_179057.1; NCBITaxon: 197</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010956 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010956">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010956</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A total of 840 Light Sussex chickens were used to evaluate a Salmonella enterica serovar Typhimurium DeltaaroA vaccine  expressing the C. jejuni amino acid binding protein CjaA.  Chickens were given the vaccine at 1-day-old and two weeks later by oral gavage, then challenged after a further two weeks with C. jejuni. Across six biological replicates, statistically significant reductions in caecal C. jejuni of c. 1.4log(10) colony-forming units/g were observed at three and four weeks post-challenge relative to age-matched unvaccinated birds. Protection was associated with the induction of CjaA-specific serum IgY and biliary IgA [PubMed: 19853682].</rdfs:comment>
        <rdfs:label>CjaA from C. jejuni</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 134; NCBI Protein GI: 1813949; NCBITaxon: 197</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010957 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010957">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015473"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010957</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Pvs25</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 141; NCBITaxon: 5855</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010958 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010958">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010958</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Aotus monkeys were challenged with the virulent Vietnam Oak Knoll (FVO) strain of P. falciparum.  Vaccination of A. nancymai with yMSP1(19) induced protective immune responses.  Both of the A. nancymai vaccinated with yMSP1(19) self-resolved an otherwise lethal infection [PubMed: 8529111].</rdfs:comment>
        <rdfs:label>MSP1 from P. falciparum</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 143; NCBI Protein GI: 94420988; NCBITaxon: 5833</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010959 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010959">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010771"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010959</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>RESA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 144</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010960 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010960">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010960</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study compared the immunogenicity and protective efficacy of recombinant DOBV nucleocapsid protein (rDOBV N, S) given with Alum or Freund&apos;s as adjuvant, or PBS, in C57/BL6 mice.   Mice receiving rDOBV N with Freund&apos;s adjuvant were protected from challenge (75% protected) [PubMed: 15364453].</rdfs:comment>
        <rdfs:label>S nucleocapsid protein from Dobrava-Belgrade virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 146; NCBI Gene GI: 2656266; NCBI Protein GI: 38505524; NCBI Protein Accession: NP_942553; NCBITaxon: 12506</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010961 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010961">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010961</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study developed replication-competent vaccines against EBOV and MARV based on attenuated recombinant vesicular stomatitis virus vectors expressing either the EBOV glycoprotein or MARV glycoprotein from Lake Victoria marburgvirus - Musoke. A single intramuscular injection of the EBOV or MARV vaccine elicited completely protective immune responses in nonhuman primates against lethal EBOV or MARV challenges [PubMed: 15937495].</rdfs:comment>
        <rdfs:label>GP from Lake Victoria marburgvirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 150; NCBI Protein GI: 77543430; NCBITaxon: 33727</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010962 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010962">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010962</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>This is a protective antigen [PubMed: 17239499].</rdfs:comment>
        <rdfs:label>Bp26</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 232; NCBI Gene GI: 1196247; NCBI Protein GI: 17986819; NCBI Protein Accession: NP_539453; NCBITaxon: 224914</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010963 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010963">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010963</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>RpsL</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 236; NCBI Gene GI: 1196463; NCBI Protein GI: 161511151; NCBI Protein Accession: NP_539669; NCBITaxon: 224914</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010964 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010964">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010964</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Iss</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 240; NCBI Gene GI: 5616654; NCBI Protein GI: 157418230; NCBI Protein Accession: YP_001481302; NCBITaxon: 405955</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010965 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010965">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010965</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>FyuA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 247; NCBI Gene GI: 4492541; NCBI Protein GI: 117624167; NCBI Protein Accession: YP_853080; NCBITaxon: 405955</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010966 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010966">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010966</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Brucella Omp25 is a protective antigen [PubMed: 17049676].</rdfs:comment>
        <rdfs:label>Omp25</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 253; NCBI Gene GI: 1196960; NCBI Protein GI: 17987532; NCBI Protein Accession: NP_540166; NCBITaxon: 224914</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010967 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010967">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010967</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Brucella IalB is a protective antigen [PubMed: 17049676].</rdfs:comment>
        <rdfs:label>IalB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 254; NCBI Gene GI: 1197295; NCBI Protein GI: 17987867; NCBI Protein Accession: NP_540501; NCBITaxon: 224914</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010968 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010968">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010968</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Brucella bacterioferritin is a protective antigen [PubMed: 11447155 ]</rdfs:comment>
        <rdfs:label>Bfr from B. melitensis biovar Abortus 2308</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 255; NCBI Gene GI: 3828133; NCBI Protein GI: 83269559; NCBI Protein Accession: YP_418850; NCBITaxon: 359391</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010969 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010969">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010969</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>protective antigen [PubMed: 17239499]</rdfs:comment>
        <rdfs:label>Tig</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 256; NCBI Gene GI: 1196780; NCBI Protein GI: 17987352; NCBI Protein Accession: NP_539986; NCBITaxon: 224914</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010970 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010970">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010970</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Brucella DnaK is a protective antigen [PubMed: 17686554].</rdfs:comment>
        <rdfs:label>DnaK from Brucella</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 257; NCBI Gene GI: 3341115; NCBI Protein GI: 62290965; NCBI Protein Accession: YP_222758; NCBITaxon: 262698</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010971 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010971">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010971</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Brucella SurA is a protective antigen [PubMed: 17686554].</rdfs:comment>
        <rdfs:label>SurA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 258; NCBI Gene GI: 3787419; NCBI Protein GI: 82699574; NCBI Protein Accession: YP_414148; NCBITaxon: 359391</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010972 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010972">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010972</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Brucella Omp19 is a protective antigen [PubMed: 18981242].</rdfs:comment>
        <rdfs:label>Omp19</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 259; NCBI Gene GI: 3788831; NCBI Protein GI: 82700695; NCBI Protein Accession: YP_415269; NCBITaxon: 359391</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010973 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010973">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010973</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Brucella Omp16 is a protective antigen [PubMed: 18981242].</rdfs:comment>
        <rdfs:label>Omp16</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 260; NCBI Gene GI: 3788229; NCBI Protein GI: 82700483; NCBI Protein Accession: YP_415057; NCBITaxon: 359391</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010974 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010974">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010974</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 10710308]</rdfs:comment>
        <rdfs:label>GNA1946</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 266; NCBI Gene GI: 904205; NCBI Protein GI: 15677776; NCBI Protein Accession: NP_274940; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010975 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010975">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010975</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 10710308]</rdfs:comment>
        <rdfs:label>GNA1220</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 267; NCBI Gene GI: 903642; NCBI Protein GI: 15677093; NCBI Protein Accession: NP_274245; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010976 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010976">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010976</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen[PubMed: 10710308]</rdfs:comment>
        <rdfs:label>GNA1162</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 268; NCBI Gene GI: 903582; NCBI Protein GI: 15677037; NCBI Protein Accession: NP_274189; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010977 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010977">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010977</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 10710308]</rdfs:comment>
        <rdfs:label>GNA992 (hsf)</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 269; NCBI Gene GI: 903112; NCBI Protein GI: 15676883; NCBI Protein Accession: NP_274028; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010978 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010978">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010978</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 10710308]</rdfs:comment>
        <rdfs:label>GNA33</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 270; NCBI Gene GI: 902136; NCBI Protein GI: 15675973; NCBI Protein Accession: NP_273099; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010979 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010979">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010979</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 9104804]</rdfs:comment>
        <rdfs:label>NspA from N. meningitidis MC58</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 271; NCBI Gene GI: 902774; NCBI Protein GI: 15676561; NCBI Protein Accession: NP_273705; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010980 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010980">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010980</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 16825336][PubMed: 12045242] with GeneID: 902509. However, according to sequence analysis, this nadA is not the same NadA that was found to be protective antigen  [PubMed: 16825336][PubMed: 12045242].</rdfs:comment>
        <rdfs:label>NadA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 272; NCBI Gene GI: 904134; NCBI Protein GI: 15677822; NCBI Protein Accession: NP_274986; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010981 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010981">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010981</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen [PubMed: 16825336]</rdfs:comment>
        <rdfs:label>GNA1870</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 273; NCBI Gene GI: 904318; NCBI Protein GI: 15677705; NCBI Protein Accession: NP_274866; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010982 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010982">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010982</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen as shown in some assays [PubMed: 16825336]</rdfs:comment>
        <rdfs:label>GNA2091</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 274; NCBI Gene GI: 903958; NCBI Protein GI: 15677911; NCBI Protein Accession: NP_275079; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010983 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010983">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010983</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective antigen as shown in some assays [PubMed: 16825336]</rdfs:comment>
        <rdfs:label>GNA1030</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 275; NCBI Gene GI: 903167; NCBI Protein GI: 15676917; NCBI Protein Accession: NP_274064; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010984 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010984">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010984</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A vaccine made by Hma from E. coli strain CFT073 and 536 induced protection to the infection of virulent  strain CFT073 and 536,  respectively, in the bladder in the CBA/J mice.  [PubMed: 19806177].</rdfs:comment>
        <rdfs:label>Hma</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 278; NCBI Gene GI: 1037732; NCBI Protein GI: 26248334; NCBI Protein Accession: NP_754374; NCBITaxon: 199310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010985 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010985">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010985</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with IreA protects against urinary tract colinization by E.coli CFT073 and reduces colinization by E.coli 536 in the bladder of CBA/J mice [PubMed: 19806177].</rdfs:comment>
        <rdfs:label>IreA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 279; NCBI Gene GI: 1037614; NCBI Protein GI: 26250982; NCBI Protein Accession: NP_757022; NCBITaxon: 199310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010986 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010986">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010986</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with IutA protects against urinary tract colinization by E.coli CFT073 in the bladders of CBA/J mice [PubMed: 19806177].</rdfs:comment>
        <rdfs:label>IutA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 280; NCBI Gene GI: 1039578; NCBI Protein GI: 26249458; NCBI Protein Accession: NP_755498; NCBITaxon: 199310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010987 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010987">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010987</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Antibodies directed at the putative binding region of FimH (anti- s-FimH1-25) significantly reduced E. coli bladder infections in the experimental mouse model of urinary tract infections [PubMed: 9276729].</rdfs:comment>
        <rdfs:label>FimH</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 281; NCBI Gene GI: 948847; NCBI Protein GI: 16132141; NCBI Protein Accession: NP_418740; NCBITaxon: 511145</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010988 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010988">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010988</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Active immunization of BALB/c mice with IroN antigen in Freund&apos;s adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed:  17145948 ].</rdfs:comment>
        <rdfs:label>IroN from Escherichia coli</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 282; NCBI Gene GI: 7379404; NCBI Protein GI: 222104801; NCBI Protein Accession: YP_002539290; NCBITaxon: 562</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010989 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010989">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010989</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Active immunization of BALB/c mice with C0393  antigen in Freund&apos;s adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948].</rdfs:comment>
        <rdfs:label>C0393</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 283; NCBI Gene GI: 1034958; NCBI Protein GI: 26246291; NCBI Protein Accession: NP_752330; NCBITaxon: 199310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010990 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010990">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010990</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Active immunization of BALB/c mice with C4424 antigen in Freund&apos;s adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948].</rdfs:comment>
        <rdfs:label>C4424</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 284; NCBI Gene GI: 1038067; NCBI Protein GI: 26250246; NCBI Protein Accession: NP_756286; NCBITaxon: 199310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010991 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010991">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010991</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Active immunization of BALB/c mice with recombinant E. coli protein C3389 antigen in Freund&apos;s adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948].</rdfs:comment>
        <rdfs:label>C3389</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 285; NCBI Gene GI: 1039252; NCBI Protein GI: 26249224; NCBI Protein Accession: NP_755264; NCBITaxon: 199310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010992 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010992">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010777"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010992</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>S. flexneri M90T is a colonisation-defective mutant with a transposon in fnr, which encodes a regulator of anaerobic metabolism. To establish whether FNR-mediated repression of spa32 and spa33 contributes to increased Shigella entry into cells in an anaerobic cabinet, recombinant M90T strains were constructed which contain spa32 and spa33 under the control of either their native promoters (M90Tp32/33) or promoters with disrupted FNR boxes (M90Tp#32/#33).The presence in M90T of spa32 and spa33 alleles that are not repressed by FNR led to IpaB secretion during anaerobic growth, and loss of the increased entry of Shigella into cells in an anaerobic cabinet [PubMed: 20436458].</rdfs:comment>
        <rdfs:label>Spa32</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 288; NCBI Gene GI: 876502; NCBI Protein GI: 13449098; NCBI Protein Accession: NP_085314; NCBITaxon: 424718</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010993 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010993">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010766"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010993</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Oral immunization of FaeG-expressing L. lactis exhibits a protective response against ETEC infection in mice [PubMed: 19277476].</rdfs:comment>
        <rdfs:label>ECSE_P3-0034</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 289; NCBI Gene GI: 7003192; NCBI Protein GI: 209921909; NCBI Protein Accession: YP_002295988; NCBITaxon: 409438</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010994 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010994">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010777"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010994</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The invasiveness and virulence of Shigella spp. are largely due to the expression of plasmid-encoded virulence factors, among which are the invasion plasmid antigens (IpaB, IpaC, and IpaD). Recent observations have indicated that the Ipa proteins (IpaB, IpaC, and possibly IpaD) form a multiprotein complex capable of inducing the phagocytic event which internalizes the bacterium.  Researchers isolated a complex of invasins and LPS from water-extractable antigens of virulent shigellae.  Western blot analysis of the complex indicates that all of the major virulence antigens of Shigella, including IpaB, IpaC, and IpaD, and LPS are components of this macromolecular complex.  Guinea pigs (keratoconjunctivitis model) or mice (lethal lung model) immunized intranasally with purivied invasin complex (invaplex) on days 0, 14, and 28 and challenged 3 weeks later with virulent shigellae were protected from disease (P&lt;0.01 for both animal models) [PubMed: 11083774].</rdfs:comment>
        <rdfs:label>IpaB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 307; NCBI Protein GI: 22036246; NCBITaxon: 42897</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010995 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010995">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010777"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010995</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The invasiveness and virulence of Shigella spp. are largely due to the expression of plasmid-encoded virulence factors, among which are the invasion plasmid antigens (IpaB, IpaC, and IpaD). Recent observations have indicated that the Ipa proteins (IpaB, IpaC, and possibly IpaD) form a multiprotein complex capable of inducing the phagocytic event which internalizes the bacterium.  Researchers isolated a complex of invasins and LPS from water-extractable antigens of virulent shigellae.  Western blot analysis of the complex indicates that all of the major virulence antigens of Shigella, including IpaB, IpaC, and IpaD, and LPS are components of this macromolecular complex.  Guinea pigs (keratoconjunctivitis model) or mice (lethal lung model) immunized intranasally with purivied invasin complex (invaplex) on days 0, 14, and 28 and challenged 3 weeks later with virulent shigellae were protected from disease (P&lt;0.01 for both animal models) [PubMed: 11083774].</rdfs:comment>
        <rdfs:label>IpaC</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 308; NCBI Protein GI: 47056; NCBITaxon: 42897</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010996 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010996">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010777"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010996</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The invasiveness and virulence of Shigella spp. are largely due to the expression of plasmid-encoded virulence factors, among which are the invasion plasmid antigens (IpaB, IpaC, and IpaD). Recent observations have indicated that the Ipa proteins (IpaB, IpaC, and possibly IpaD) form a multiprotein complex capable of inducing the phagocytic event which internalizes the bacterium.  Researchers isolated a complex of invasins and LPS from water-extractable antigens of virulent shigellae.  Western blot analysis of the complex indicates that all of the major virulence antigens of Shigella, including IpaB, IpaC, and IpaD, and LPS are components of this macromolecular complex.  Guinea pigs (keratoconjunctivitis model) or mice (lethal lung model) immunized intranasally with purivied invasin complex (invaplex) on days 0, 14, and 28 and challenged 3 weeks later with virulent shigellae were protected from disease (P&lt;0.01 for both animal models) [PubMed: 11083774].</rdfs:comment>
        <rdfs:label>IpaD</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 309; NCBI Protein GI: 22036352; NCBITaxon: 42897</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010997 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010997">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010776"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010997</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Thirty-day-old chickens were immunized intramuscularly with purified IroN from Salmonella Typhimurium mixed with Freund&apos;s incomplete adjuvant; the chickens were then challenged intravenously with Salmonella Enteritidis. The mortality rate of immunized chickens was 10%. On the other hand, that of control chickens was 80% [PubMed: 20095157].</rdfs:comment>
        <rdfs:label>IroN from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 318; NCBI Protein GI: 259475459; NCBITaxon: 90371</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010998 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010998">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010776"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010998</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers evaluated the immunogenicity and protective efficacy of GroEL of Salmonella enterica serovar Typhi against lethal infection by S. typhi Ty2 in mice with or without adjuvants.  Immunization of mice with GroEL-alone, GroEL + alum, and GroEL + CFA provided 70, 50 and 80% protection, respectively, against lethal challenge by S. typhi in mice.  The present study shows that GroEL forms an ideal candidate molecule to develop a recombinant protein based vaccine against human typhoid [PubMed: 19851830].</rdfs:comment>
        <rdfs:label>GroEL from Salmonella spp.</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 320; NCBI Gene GI: 1068458; NCBI Protein GI: 29144631; NCBI Protein Accession: NP_807973; NCBITaxon: 209261</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010999 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0010999">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010776"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0010999</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The entire SopB and SifB genes were cloned into DNA vaccine vectors and were administered along with live attenuated Salmonella.  It was found that SopB vaccination reduced the bacterial burden of organs by about 5-fold on day 4 and day 8 after challenge with virulent Salmonella and proved to be a more efficient vaccination strategy than live attenuated bacteria alone [PubMed: 19428891].</rdfs:comment>
        <rdfs:label>SopB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 321; NCBI Protein GI: 54036439; NCBITaxon: 90371</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011000">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011000</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Oral immunization of mice with ZJ111/pcDNA3-SAG1 elicited specific humoral responses and stimulated proliferation of splenocytes (P&lt;0.05). Mice immunized with ZJ111/pcDNA3-SAG1 displayed significant protection against an intraperitoneally challenge with 500 tachyzoite forms of T. gondii RH strain. Vaccination at 10(7) and 10(8)CFU per mice provided a 20% and 10% survival rate comparing 100% mortality of the non-immunized mice, exhibiting longer living time and better survival rate [PubMed: 18590785].</rdfs:comment>
        <rdfs:label>SAG1 from Toxoplasma gondii</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 326; NCBI Gene GI: 7900172; NCBI Protein GI: 237839159; NCBI Protein Accession: XP_002368877; NCBITaxon: 508771</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011001</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Modified YscF antigens were able to partially protect immunized mice at various levels against lethal challenge with Y. pestis KIM 1001 strain [PubMed: 18291562].</rdfs:comment>
        <rdfs:label>YscF from Y. pestis KIM 10</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 338; NCBI Gene GI: 1149286; NCBI Protein GI: 31795470; NCBI Protein Accession: NP_857922; NCBITaxon: 187410</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011002</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Modified yopD antigens were able to partially protect immunized mice at various levels against lethal challenge with Y. pestis KIM 1001 strain [PubMed: 18291562].</rdfs:comment>
        <rdfs:label>YopD from Y. pestis KIM 10</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 339; NCBI Gene GI: 1149313; NCBI Protein GI: 31795494; NCBI Protein Accession: NP_857949; NCBITaxon: 187410</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011003</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Modified yopO antigens were able to partially protect immunized mice at various levels against lethal challenge with Y. pestis KIM 1001 strain [PubMed: 18291562].</rdfs:comment>
        <rdfs:label>YopO</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 340; NCBI Gene GI: 5798322; NCBI Protein GI: 162417777; NCBI Protein Accession: YP_001604502; NCBITaxon: 349746</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011004</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intranasal immunization with flagellin and the F1 antigen was protective against intranasal challenge with virulent Y. pestis CO92, with 93 to 100% survival of immunized mice. Lastly, vaccination of cynomolgus monkeys with flagellin and a fusion of the F1 and V antigens of Y. pestis induced a robust antigen-specific IgG antibody response [PubMed: 16428759].</rdfs:comment>
        <rdfs:label>YPMT1.84 (F1 capsule antigen)</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 341; NCBI Gene GI: 1172839; NCBI Protein GI: 16082876; NCBI Protein Accession: NP_395430; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011005</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using a mouse model, YPO0606 (yapF) partially protected mice from infection with Y. pestis at a high challenge dosage (200x LD(50)) [PubMed: 19651863].</rdfs:comment>
        <rdfs:label>YapF</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 342; NCBI Gene GI: 1173449; NCBI Protein GI: 218927800; NCBI Protein Accession: YP_002345675; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011006</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using a mouse plague model, YPO1914 (irp7) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863].</rdfs:comment>
        <rdfs:label>Irp7</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 343; NCBI Gene GI: 1174753; NCBI Protein GI: 218929030; NCBI Protein Accession: YP_002346905; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011007</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using a mouse plague model, YPO0612 may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863].</rdfs:comment>
        <rdfs:label>YPO0612</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 344; NCBI Gene GI: 1173455; NCBI Protein GI: 218927806; NCBI Protein Accession: YP_002345681; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011008">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011008</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using a mouse plague model, YPO3119 (htpG) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863].</rdfs:comment>
        <rdfs:label>HtpG</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 345; NCBI Gene GI: 1175934; NCBI Protein GI: 218930152; NCBI Protein Accession: YP_002348027; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011009</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using a mouse plague model, YPO3047 (ydeN) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863].</rdfs:comment>
        <rdfs:label>YdeN</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 346; NCBI Gene GI: 1175868; NCBI Protein GI: 218930092; NCBI Protein Accession: YP_002347967; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011010">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011010</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using a mouse plague model, YPO1377 (lolA) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863].</rdfs:comment>
        <rdfs:label>LolA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 347; NCBI Gene GI: 1174218; NCBI Protein GI: 218928525; NCBI Protein Accession: YP_002346400; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011011</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using a mouse plague model, YPCD1.05c (yerA) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863].</rdfs:comment>
        <rdfs:label>YerA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 348; NCBI Gene GI: 1172650; NCBI Protein GI: 16082696; NCBI Protein Accession: NP_395142; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011012">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011012</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using a mouse plague model, YPO0420 may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863].</rdfs:comment>
        <rdfs:label>YPO0420</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 349; NCBI Gene GI: 1173265; NCBI Protein GI: 218927621; NCBI Protein Accession: YP_002345496; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011013</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using a mouse plague model, YPO3720 (hpmB) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863].</rdfs:comment>
        <rdfs:label>HpmB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 350; NCBI Gene GI: 1176539; NCBI Protein GI: 218930726; NCBI Protein Accession: YP_002348601; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011014</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study tested the efficacy of 2 proteins, Psn and a portion of LcrV in protecting mice against virulent Yersinia pestis challenge.  Results show that the truncated LcrV protein delivered by RASV is sufficient to afford a full protective immune response in a mouse model of bubonic plague and the Psn protein afforded partial protection in a non-optimized system [PubMed: 17966435].</rdfs:comment>
        <rdfs:label>Psn</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 351; NCBI Gene GI: 1147351; NCBI Protein GI: 22126288; NCBI Protein Accession: NP_669711; NCBITaxon: 187410</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011015">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011015</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study evaluated the humoral immune response of mice that survived lethal Y. pestis aerosol challenge after antibiotic treatment.  Results indicated that one of the predominant antibody response of mice surviving pneumonic plague after treatment with antibiotics was to yopH [PubMed: 10085037].</rdfs:comment>
        <rdfs:label>YopH from Y. pestis CO92</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 352; NCBI Gene GI: 1172712; NCBI Protein GI: 16082755; NCBI Protein Accession: NP_395201; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010796"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011016</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Complexes of YopB (pYV0055), YopD, and YopE (BDE) secreted by Yersinia pseudotuberculosis were purified by affinity chromatography and used as immunogens to determine if antibodies to the translocon could provide protection against Y. pestis in mice. The YopB protein or a complex of YopB and YopD (BD) was purified and determined by vaccination to be immunogenic in mice. Mice actively vaccinated with BD or passively vaccinated with anti-BD serum were protected against lethal challenge with F1(-) Y. pestis [PubMed: 18765742].</rdfs:comment>
        <rdfs:label>pYV0055</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 354; NCBI Gene GI: 2952948; NCBI Protein GI: 51593897; NCBI Protein Accession: YP_068464; NCBITaxon: 273123</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011017">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011017</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination of mice with deF1 DNA conferred protection against subcutaneous infection with the virulent Y. pestis Kimberley53 strain, even at challenge amounts as high as 4,000 50% lethal doses [PubMed: 12496187 ].</rdfs:comment>
        <rdfs:label>Caf1 from Y. pestis</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 355; NCBI Protein GI: 48621; NCBITaxon: 632</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011018</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following passive immunization, antisera partially protected infant rats from bacteremia resulting from intraperitoneal challenge with bacteria. As assessed by immunoblotting, pooled adult human sera contained antibodies reactive with P145. Following passive immunization, these antisera partially protected infant rats from bacteremia resulting from intraperitoneal challenge with bacteria.  Antibody to P145 may contribute to protection against Brazilian purpuric fever [PubMed: 1937817].</rdfs:comment>
        <rdfs:label>P145</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 356</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010821"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011019</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The ApxI antigen is an important factor in the protection against Actinobacillus pleuropneumoniae serotype 5 infection; therefore, the protective immunity in mice following oral immunization with Saccharomyces cerevisiae expressing either ApxIA (group C) or ApxIIA (group D) alone or both (group E) was compared with that in two control groups (group A and B). The immunogenicity of the rApxIA antigen derived from the yeast was confirmed by a high survival rate and an ApxIA-specific IgG antibody response (p &lt; 0.01) [PubMed: 17993753].</rdfs:comment>
        <rdfs:label>ApxIA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 358; NCBI Protein GI: 312899; NCBITaxon: 715</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010821"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011020</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The levels of local and systemic antibodies specific to the Apx antigens were investigated in mice orally immunized with Apx antigen-expressing yeast.  Specific IgA responses to ApxIA or ApxIIA in the intestines and lungs from mice immunized with yeast expressing Apx antigens were significantly higher than those in the control groups after the second and third immunizations, respectively (p &lt; 0.05).  All mice were monitored for up to 72 h after challenge with the MLD of an A. pleuropneumoniae field isolate. Overall, the final survival rates of the vaccinated groups were higher than those of the control groups at each time point [PubMed: 17993753].</rdfs:comment>
        <rdfs:label>ApxIIA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 360; NCBI Protein GI: 52630374; NCBITaxon: 715</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011021">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010821"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011021</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following a booster vaccination, a significant (P &lt; 0.05) IgG antibody response to the CP (cps5C), LPS, and HP was detected in the vaccinated pigs. The pigs vaccinated with the CP-HP and LPS-HP conjugates exhibited significantly less mortality (P &lt; 0.05) and significantly greater weight gain (P &lt; 0.001) than unvaccinated pigs. Vaccinated pigs exhibited significantly fewer and less extensive gross pulmonary lesions (P &lt; 0.001) when compared with unvaccinated pigs [PubMed: 1455686].</rdfs:comment>
        <rdfs:label>CP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 361</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010821"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011022</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following a booster vaccination, a significant (P &lt; 0.05) IgG antibody response to the CP, LPS, and HP (APP7_1016) was detected in the vaccinated pigs. The pigs vaccinated with the CP-HP and LPS-HP conjugates exhibited significantly less mortality (P &lt; 0.05) and significantly greater weight gain (P &lt; 0.001) than unvaccinated pigs. Vaccinated pigs exhibited significantly fewer and less extensive gross pulmonary lesions (P &lt; 0.001) when compared with unvaccinated pigs [PubMed: 1455686].</rdfs:comment>
        <rdfs:label>APP7_1016</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 362; NCBI Gene GI: 6398034; NCBI Protein GI: 190150285; NCBI Protein Accession: YP_001968810; NCBITaxon: 537457</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011024">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010814"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011024</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The aroA gene of A. salmonicida was cloned in Escherichia coli, and the nucleotide sequence was determined.  Vaccination of brown trout with 10(7) CFU of A. salmonicida 644Rb aroA by intraperitoneal injection resulted in a 253-fold increase in the 50% lethal dose (LD50) compared with unvaccinated controls challenged with a virulent clinical isolate 9 weeks later [PubMed: 8478107].</rdfs:comment>
        <rdfs:label>AroA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 366; NCBI Protein GI: 512545; NCBITaxon: 645</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011025 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011025">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010814"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011025</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Passive immunisation of Atlantic salmon with rainbow trout or rabbit anti-AsaP1 antisera conferred significant protection against challenge with a virulent A. salmonicida [Ref1011:Gudmundsdottir et al., 1997]</rdfs:comment>
        <rdfs:label>AsaP1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 367; NCBI Gene GI: 4998702; NCBITaxon: 382245</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011026">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010827"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011026</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>RAP-1 (21B4) is a candidate for inclusion in a B. bovis vaccine based on its ability to induce partial protection in vaccinates, defined as a significant reduction in parasitemia upon challenge [PubMed: 1441189].</rdfs:comment>
        <rdfs:label>RAP-1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 368; NCBI Gene GI: 5479143; NCBI Protein GI: 156087004; NCBI Protein Accession: XP_001610909; NCBITaxon: 484906</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010827"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011027</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Crude extracts of Babesia bovis parasites were systematically fractionated and tested in numerous sequential vaccination/challenge experiments in adult cattle.  Two of these, GST-12D3 and GST-11C5, when used in combination were almost as protective as has been previously shown for the commercially available live attenuated vaccine [PubMed: 1441189].</rdfs:comment>
        <rdfs:label>12D3</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 371; NCBI Gene GI: 5478971; NCBI Protein GI: 156086656; NCBI Protein Accession: XP_001610737; NCBITaxon: 484906</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011028">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010827"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011028</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Crude extracts of Babesia bovis parasites were systematically fractionated and tested in numerous sequential vaccination/challenge experiments in adult cattle. A short fragment of the third antigen (21B4) has been shown to be protective [PubMed: 1441189].</rdfs:comment>
        <rdfs:label>21B4</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 373; NCBI Protein GI: 1246924; NCBITaxon: 5865</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010757"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011029</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study described the construction and evaluation of an adenovirus vaccine expressing domain 4 of Bacillus anthracis protective antigen, Ad.D4. Ad.D4 elicited antibodies to protective antigen 14 days after a single intramuscular injection, which were further increased upon boosting. Furthermore, two doses of Ad.D4 4 weeks apart were sufficient to protect 67% of mice from toxin challenge [PubMed: 16428747].</rdfs:comment>
        <rdfs:label>PagA from B. anthracis</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 374; NCBI Protein GI: 9280533; NCBITaxon: 1392</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011030">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011030</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A combination of the 69-kDa outer membrane protein and filamentous hemagglutinin (fhaB), both isolated from lymphocytosis promoting factor (LPF; pertussis toxin) minus mutants of Bordetella pertussis, is protective in the mouse intracerebral challenge potency (Kendrick) test [PubMed: 2056199].</rdfs:comment>
        <rdfs:label>FhaB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 375; NCBI Protein GI: 3980256; NCBITaxon: 520</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011031">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011031</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A study demonstrated that passive immunization with specific anti-B. pertussis adenylate cyclase antibodies or active immunization with purified B. pertussis secreted adenylate cyclase (cyaA) protect mice against a lethal respiratory challenge with B. pertussis or B. parapertussis. Results suggest that adenylate cyclase might be the primary cytotoxin responsible for mouse pulmonary lesions during respiratory tract infection with B. pertussis or with the related species B. parapertussis and is a protective antigen of B. pertussis [PubMed: 2622329].</rdfs:comment>
        <rdfs:label>CyaA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 376; NCBI Protein GI: 580668; NCBITaxon: 520</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011032">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011032</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model.  These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973].</rdfs:comment>
        <rdfs:label>PtxD</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 377; NCBI Protein GI: 225311181; NCBITaxon: 520</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011033</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers constructed isogenic mutants of B. pertussis Tohama expressing the alleles ptxA1 or ptxA2 and prn1 or prn2 and compared the efficacies of an acellular pertussis vaccine against the mutants in a mouse model. While the vaccine was effective against all of the B. pertussis strains regardless of the allele expression pattern, the strain expressing ptxA1 and prn2 displayed a survival advantage over the other strains [PubMed: 20357056].</rdfs:comment>
        <rdfs:label>Prn</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 378; NCBI Gene GI: 2664290; NCBI Protein GI: 33592195; NCBI Protein Accession: NP_879839; NCBITaxon: 257313</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011034</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model.  These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973].</rdfs:comment>
        <rdfs:label>PtxA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 379; NCBI Gene GI: 2665068; NCBI Protein GI: 33594638; NCBI Protein Accession: NP_882282; NCBITaxon: 257313</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011035">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011035</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A soluble fraction obtained from Bordetella pertussis was evaluated as adjuvant for the pertussis component of the Diphtheria-Pertussis-Tetanus (DPT) vaccine. High levels of antibodies were induced, and a 78% protection rate of mice challenged with live B. pertussis was observed. Two proteins were identified as the 73 kDa N-terminal alpha-domain of BrkA autotransporter protein and the Cpn60/60 kDa chaperonin. Both stimulated antibodies against pertussis and induced a 42% protection rate against the challenge [PubMed: 17011680].</rdfs:comment>
        <rdfs:label>Cpn60</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 382; NCBI Protein GI: 968920; NCBITaxon: 520</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011036</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A soluble fraction obtained from Bordetella pertussis was evaluated as adjuvant for the pertussis component of the Diphtheria-Pertussis-Tetanus (DPT) vaccine. High levels of antibodies were induced, and a 78% protection rate of mice challenged with live B. pertussis was observed. Two proteins were identified as the 73 kDa N-terminal alpha-domain of BrkA autotransporter protein and the Cpn60/60 kDa chaperonin. Both stimulated antibodies against pertussis and induced a 42% protection rate against the challenge [PubMed: 17011680].</rdfs:comment>
        <rdfs:label>BrkA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 383; NCBI Protein GI: 562026; NCBITaxon: 520</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011037 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011037">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011037</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model.  These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973].</rdfs:comment>
        <rdfs:label>PtxB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 384; NCBI Protein GI: 225311180; NCBITaxon: 520</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011038">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011038</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model.  These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973].</rdfs:comment>
        <rdfs:label>PtxC</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 385; NCBI Protein GI: 225311183; NCBITaxon: 520</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011039 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011039">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010847"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011039</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model. These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973].</rdfs:comment>
        <rdfs:label>PtxE</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 386; NCBI Protein GI: 225311182; NCBITaxon: 520</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010802"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011040</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protection against a BHV-1 challenge was obtained in calves immunized with the plasmid encoding tgD-VP22 (UL49), as shown by significant reductions in viral excretion [PubMed: 15650221].</rdfs:comment>
        <rdfs:label>UL49 from Bovine herpesvirus 1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 389; NCBI Gene GI: 1487397; NCBI Protein GI: 9629826; NCBI Protein Accession: NP_045310; NCBITaxon: 10320</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011041">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010802"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011041</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Calves were injected intranasally with either AdCMVgC or AdCMVgD (US6) or a combination of these two recombinants or a commercially available live vaccine for comparison. The highest BHV-1 neutralizing antibody titres were obtained with AdCMVgD (US6) followed by the live vaccine and to a lower extent with the combination of the two recombinants. Calves were protected against intranasal BHV-1 challenge performed 3 weeks after the second immunization [PubMed: 11818166].</rdfs:comment>
        <rdfs:label>US6 from Bovine herpesvirus 1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 390; NCBI Gene GI: 1487406; NCBI Protein GI: 9629886; NCBI Protein Accession: NP_045370; NCBITaxon: 10320</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011042">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010802"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011042</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization of calves with truncated gpI (US7) protein induced gpI-specific nasal IgA, IgG1, serum neutralizing antibodies and gpI-specific peripheral lymphocyte proliferation. All immunized calves were protected from clinical disease after BHV-1 challenge. Further, nine of ten immunized calves had no intranasal viral shedding [PubMed: 8147097].</rdfs:comment>
        <rdfs:label>US7</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 392; NCBI Gene GI: 4783432; NCBI Protein GI: 9629887; NCBI Protein Accession: NP_045371; NCBITaxon: 10320</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011043">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010802"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011043</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A DNA vaccine expressing glycoprotein C (gC, UL44) of bovine herpesvirus-1 (BHV-1) was evaluated for inducing immunity in bovines.  Results indicate that DNA immunization with gC could induce neutralizing antibody and lymphoproliferative responses with BHV-1 responsive memory B cells in bovines. However, the immunity developed sufficient for only partial protection against BHV-1 challenge [PubMed: 11182496].</rdfs:comment>
        <rdfs:label>UL44 from Bovine herpesvirus 1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 393; NCBI Gene GI: 4783424; NCBI Protein GI: 9629830; NCBI Protein Accession: NP_045314; NCBITaxon: 10320</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011044">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011044</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Chitosan-DNA vaccines were prepared by embedding pcDNA3.1(+)-cadF and pcDNA3.1(+)-peblA with chitosan respectively.  The mice immunized with chitosan-DNA vaccines have generated high levels of IgA and IgG from the sera and IgA from the intestinal secretions and the P/N value went up to 20.58, 30.13 and 6.87 respectively.  The chitosan-DNA vaccines induced strongest level of protection in BALB/c mice against challenge with C. jejuni HS:19 strain and the protective efficacies was 93.70 [PubMed: 18206008].</rdfs:comment>
        <rdfs:label>CadF</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 396; NCBI Protein GI: 4704601; NCBITaxon: 197</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011045">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011045</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Chitosan-DNA vaccines were prepared by embedding pcDNA3.1(+)-cadF and pcDNA3.1(+)-peblA with chitosan respectively. The mice immunized with chitosan-DNA vaccines have generated high levels of IgA and IgG from the sera and IgA from the intestinal secretions and the P/N value went up to 20.58, 30.13 and 6.87 respectively. The chitosan-DNA vaccines induced strongest level of protection in BALB/c mice against challenge with C. jejuni HS:19 strain and the protective efficacies was 93.70 [PubMed: 18206008].</rdfs:comment>
        <rdfs:label>Peb1A</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 397; NCBI Protein GI: 112360246; NCBITaxon: 192222</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011046">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011046</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice were immunized intranasally with two doses of 3 to 50 microgram of MBP-FlaA.  The protective efficacies of a 50 microgram of MBP-FlaA plus LT(R192G) dose against disease symptoms and intestinal colonization were 81.1 and 84%, respectively. When mice which had been immunized with 50 microgram of MBP-FlaA plus LT(R192G) intranasally were challenged orally with 8 x 10(10), 8 x 10(9), or 8 x 10(8) cells of strain 81-176, the protective efficacies against intestinal colonization at 7 days postinfection were 71.4, 71.4, and 100%, respectively [PubMed: 10531231].</rdfs:comment>
        <rdfs:label>FlaA from C. jejuni 81-176</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 398; NCBI Gene GI: 4682159; NCBI Protein GI: 121612545; NCBI Protein Accession: YP_001000997; NCBITaxon: 354242</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011047</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model.  Immunization with FspA1 resulted in 57.8% protection without adjuvant or 63.8% protection with adjuvant against homologous challenge with 81-176 [PubMed: 18426878].</rdfs:comment>
        <rdfs:label>FspA1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 399; NCBI Protein GI: 116292649; NCBITaxon: 197</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011048 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011048">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011048</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model.  All three proteins were immunogenic, FlaC provided an 18% protection against disease from C. jejuni 81-176 [PubMed: 18426878].</rdfs:comment>
        <rdfs:label>FlaC</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 400; NCBI Gene GI: 4682885; NCBI Protein GI: 121612344; NCBI Protein Accession: YP_001000416; NCBITaxon: 354242</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011049">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011049</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model.  Immunization with FspA2 provided 38.4% (without adjuvant) or 47.2% (with adjuvant) protection against disease from homologous challenge with CG8486 [PubMed: 18426878].</rdfs:comment>
        <rdfs:label>FspA2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 409; NCBI Protein GI: 116292677; NCBITaxon: 197</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011050">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010797"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011050</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A DNA vaccination trial was performed on sheep to determine whether vaccination with bovine leukemia virus (BLV) transactivator Tax DNA is effective against BLV infection.  Results showed higher levels of virus titers in control sheep than those in Tax-vaccinated sheep. Higher levels of IFN-gamma mRNA expression have been demonstrated in vaccinated sheep after the challenge. These results suggested that Th1 type immune response induced by Tax DNA vaccine inhibited BLV propagation in vaccinated sheep at the early phase of infection [PubMed: 14665749].</rdfs:comment>
        <rdfs:label>Tax</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 410; NCBI Gene GI: 2760848; NCBI Protein GI: 9626228; NCBI Protein Accession: NP_056895; NCBITaxon: 11901</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010797"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011051</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The bovine leukemia virus (BLV) envelope gene encoding extracellular glycoprotein gp51 (encoded by env gene) and transmembrane glycoprotein gp30 was cloned into a vehicle expression vector under the human cytomegalovirus (CMV) intermediate early promoter. The intramuscular injection of this plasmid vector generated a cellular immune response. Seven out of ten cows vaccinated with the DNA construct resisted a drastic challenge [PubMed: 10824867].</rdfs:comment>
        <rdfs:label>Env/Rex/Tax</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 411; NCBI Gene GI: 2760849; NCBI Protein GI: 9626230; NCBI Protein Accession: NP_056898; NCBITaxon: 11901</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011052 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011052">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010809"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011052</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Young mink kits (n=8) were vaccinated with DNA plasmids encoding the viral haemagglutinin protein (H) of a vaccine strain of Canine distemper virus (CDV).  The mink were protected against viraemia, lymphopenia, clinical disease and changes in the percentage of IFN-gamma producing peripheral blood leucocytes after challenge inoculation with a recent wild type strain of CDV. Essentially, these results demonstrate that early life DNA vaccination with the H gene of a CDV vaccine strain induced robust protective immunity against a recent wild type CDV [PubMed: 19596418].</rdfs:comment>
        <rdfs:label>CDVgp6 haemagglutinin protein H</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 412; NCBI Gene GI: 1489792; NCBI Protein GI: 9630651; NCBI Protein Accession: NP_047206; NCBITaxon: 11232</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011053 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011053">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010809"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011053</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study reports the engineering and the characterization of two replication-competent canine adenovirus type 2 (CAV2)-based vaccines expressing, respectively, the CDV hemagglutinin (HA) and fusion (F) antigens (CDVgp5). We first demonstrated that the intranasal vaccination with a mixture of both recombinant CAV2s provides an excellent level of protection in seronegative puppies, confirming the value of replication-competent adenovirus-based vectors for mucosal vaccination [PubMed: 12297394].</rdfs:comment>
        <rdfs:label>CDVgp5</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 413; NCBI Gene GI: 1489793; NCBI Protein GI: 9630650; NCBI Protein Accession: NP_047205; NCBITaxon: 11232</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010807"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011054</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A vaccine based upon a recombinant plant virus (CPMV-PARVO1), displaying a peptide derived from the VP2 capsid protein of canine parvovirus (CPV), has previously been described. To date, studies with the vaccine have utilized viable plant chimaeric particles (CVPs).  Results show that the inactivated CVP is able to protect dogs from a lethal challenge with CPV following parenteral immunization with the vaccine.  Dogs immunized with the inactivated CPMV-PARVO1 in adjuvant displayed no clinical signs of disease and shedding of CPV in faeces was limited following CPV challenge. [PubMed: 11395200].</rdfs:comment>
        <rdfs:label>VP2 from Canine parvovirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 414; NCBI Gene GI: 1489588; NCBITaxon: 10788</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011055">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010807"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011055</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>This study shows that a plasmid DNA (pGT36VP1) encoding the full length VP1 region of canine parvovirus (CPV) induces immunity that protects dogs against challenge with virulent virus [PubMed: 9569471].</rdfs:comment>
        <rdfs:label>VP1 from Canine parvovirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 415; NCBI Gene GI: 1489587; NCBITaxon: 10788</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011056 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011056">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011056</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.  DNA pol III Gamma and Tau (CP #1, dnaX) was found to be protective.  CP #1 (dnaX) was more protective than the live-vaccine, positive control.  [PubMed: 15811648].</rdfs:comment>
        <rdfs:label>DnaX</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 416; NCBI Protein GI: 62148024; NCBITaxon: 218497</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011057 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011057">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011057</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #2, gatC) was found to be protective. Three of the clones (CP #1) elicited protection that was statistically higher than the unvaccinated control, which has high variance [PubMed: 15811648].</rdfs:comment>
        <rdfs:label>GatC</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 417; NCBI Protein GI: 62184917; NCBITaxon: 218497</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011058 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011058">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011058</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.   Protective clone CP #4 (OMP90A, pomp90A) was diluted 1/2000 in a non-protective sublibrary pool of clones. This CP #4-spiked sublibrary conferred protection.  Five clones were significantly more protective than the genes encoding fewer than 50 amino acids (CP #1 and 7, p-value of less than 0.05 when comparing lung weights). [PubMed: 15811648].</rdfs:comment>
        <rdfs:label>Pomp90A</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 418; NCBI Protein GI: 187438939; NCBITaxon: 83555</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011059 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011059">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011059</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.  CP #5 (Transglycolase/transpeptidase, CAB049 putative penicillin-binding protein) was significantly more protective than the genes encoding fewer than 50 amino acids (p-value of less than 0.05 when comparing lung weights).  The chlamydial loads generally tracked with protection and the most protective genes were significantly lower than in unvaccinated controls (p &lt; 0.05 in the Mannhitney U-test for genes CP #1, 2, 4, 9, 10) [PubMed: 15811648].</rdfs:comment>
        <rdfs:label>CAB049 putative penicillin-binding protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 419; NCBI Protein GI: 62184696; NCBITaxon: 218497</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011060">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011060</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.  CP #7 (omlA) was significantly more protective than the genes encoding fewer than 50 amino acids (p-value of less than 0.05 when comparing lung weights). The chlamydial loads generally tracked with protection and the most protective genes were significantly lower than in unvaccinated controls (p &lt; 0.05 in the Mannhitney U-test for genes CP #1, 2, 4, 9, 10) [PubMed: 15811648].</rdfs:comment>
        <rdfs:label>OmlA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 420; NCBI Protein GI: 62184824; NCBITaxon: 218497</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011061">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010817"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011061</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system.  Of the 14 individually tested clones, CP #1 through CP #9 had positive relative protection scores.  CP #8 (CAB613, Oligopeptidase) was found to confer protection [PubMed: 15811648].</rdfs:comment>
        <rdfs:label>CAB613 putative peptidase</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 421; NCBI Protein GI: 62185225; NCBITaxon: 218497</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011062">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010833"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011062</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Animals vaccinated with Gam82 and challenged with E. maxima showed lower oocyst shedding and reduced intestinal pathology compared with non-vaccinated and parasite-challenged animals. Gam82 vaccination also stimulated the production of antigen-specific serum antibodies and induced greater levels of IL-2 and IL-15 mRNAs compared with non-vaccinated controls. These results demonstrate that the Gam82 recombinant protein protects against E. maxima and augments humoral and cell-mediated immunity [PubMed: 20178868].</rdfs:comment>
        <rdfs:label>Gam82</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 457; NCBI Protein GI: 38565038; NCBITaxon: 5804</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011063 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011063">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010823"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011063</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Birds vaccinated with Eimeria tenella microneme recombinant gene (EtMIC2) and encoded protein developed protective immunity against infection by E. tenella as assessed by significantly increased body weight gain and decreased fecal oocyst shedding compared with non-vaccinated controls. Vaccination with the EtMIC2 gene also led to protective immunity against infection by E. acervulina, but not E. maxima [PubMed: 15882535].</rdfs:comment>
        <rdfs:label>MIC2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 459; NCBI Protein GI: 225579627; NCBITaxon: 5802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011064">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010823"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011064</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Two recombinant Mycobacterium bovis BCG (rBCG) strains carrying the Eimeria tenella rhomboid gene (Rho) delivered by extrachromosomal vector pMV261 and integrative vector pMV361 were evaluated for their ability to protect chickens against E. tenella challenge. Chickens were immunized intranasal with BCG, rBCG pMV261-Rho, or rBCG pMV361-Rho twice at a 2-week interval. All the recombinant BCG immunized chickens developed specific immune responses, and there was a significant increases of the percentages of CD4(+) and CD8(+) cells compared to the control (P&lt;0.05). Challenge experiments demonstrated that the two rBCG strains could provide significant protection against E. tenella challenge [PubMed: 19117681].</rdfs:comment>
        <rdfs:label>Rho</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 460; NCBI Protein GI: 84043169; NCBITaxon: 5802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011065 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011065">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010823"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011065</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The immunization procedure of DNA vaccine pcDNA-TA4-IL-2 of Eimeria tenella, including route, dose, time of immunization and age of primary immunization of chicken, was optimized.  results illustrated that 25 microg was the optimal dose and intramuscular injection was the most effective route to induce protective immunity in Chinese Yellow chickens [PubMed: 19019543].</rdfs:comment>
        <rdfs:label>TA4</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 461; NCBI Protein GI: 84783094; NCBITaxon: 5802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011066">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010823"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011066</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The Eimeria tenella antigen gene (3-1E) and chicken interferon gamma gene (ChIFN-gamma) were subcloned into the mammalian expression vector proVAX forming the plasmids proE and prol.  After challenge the proIE-vaccinated chickens showed protective immunity as demonstrated by significantly reduced oocyst shedding [PubMed: 17274297].</rdfs:comment>
        <rdfs:label>3-1E</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 463; NCBI Protein GI: 126362934; NCBITaxon: 5802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011067 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011067">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010823"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011067</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A cDNA clone derived from sporulated oocysts of Eimeria tenella and encoding the expression product GX3262 was identified using a monoclonal antibody raised against Eimeria acervulina sporozoites.  After challenge with an experimental E. tenella infection, the greatest degree of protection in immunized broiler chickens was seen after only a single immunization of 2-day-old birds with a live recombinant E. coli preparation [PubMed: 2659532].</rdfs:comment>
        <rdfs:label>GX3262</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 464; NCBI Protein GI: 102304; NCBITaxon: 5802</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011068 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011068">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010806"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011068</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study describes experiments which demonstrate that the vaccine, (EURIFEL FeLV; Merial) that expresses the FeLV env and gag protective genes, is effective against any oronasal FeLV challenge. The protection was shown to be solid against an oronasal challenge one year after the initial vaccination, and was effective against a very severe &apos;in-contact&apos; challenge [PubMed: 12934796].</rdfs:comment>
        <rdfs:label>Env</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 465; NCBI Gene GI: 1491868; NCBI Protein GI: 9630709; NCBI Protein Accession: NP_047256; NCBITaxon: 11768</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011069 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011069">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010806"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011069</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The vaccine, (EURIFEL FeLV; Merial) that expresses the FeLV env and gag protective genes, is effective against any oronasal FeLV challenge. The protection was shown to be solid against an oronasal challenge one year after the initial vaccination, and was effective against a very severe &apos;in-contact&apos; challenge [PubMed: 12934796].</rdfs:comment>
        <rdfs:label>Gag</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 466; NCBI Protein GI: 323916; NCBITaxon: 11768</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011070 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011070">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011070</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intranasal immunization of HLA-DR4 tg mice with the single antigen FopB from F. tularensis subsp. novicida conferred significant protection against lethal pulmonary challenge with an F. tularensis subsp. holarctica live vaccine strain.</rdfs:comment>
        <rdfs:label>FopB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 468; NCBI Gene GI: 4547777; NCBI Protein GI: 118496734; NCBI Protein Accession: YP_897784; NCBITaxon: 401614</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011071 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011071">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011071</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intranasal vaccination with KKF235 (F. tularensis subsp. novicida mutant (DeltaiglB) ) protected mice from subsequent homotypic challenge with U112 as well as heterotypic challenge with F. tularensis subsp. holarctica (LVS).  Most significantly, oral immunization with KKF235 protected mice from a highly lethal subsp. tularensis (SCHU S4) pulmonary challenge [PubMed: 20016043].</rdfs:comment>
        <rdfs:label>IglB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 469; NCBI Gene GI: 4548125; NCBI Protein GI: 118497903; NCBI Protein Accession: YP_898953; NCBITaxon: 401614</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011072 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011072">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011072</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with rLm/iglC were protected against lethal challenge with F. tularensis LVS administered by the intranasal route, a route chosen to mimic airborne infection, and, most importantly, against aerosol challenge with the highly virulent Type A F. tularensis SchuS4 strain [PubMed: 19126421].</rdfs:comment>
        <rdfs:label>IglC1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 470; NCBI Gene GI: 3191591; NCBI Protein GI: 56708413; NCBI Protein Accession: YP_170309; NCBITaxon: 177416</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011073">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011073</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with rLm/iglC were protected against lethal challenge with F. tularensis LVS administered by the intranasal route, a route chosen to mimic airborne infection, and, most importantly, against aerosol challenge with the highly virulent Type A F. tularensis SchuS4 strain [PubMed: 19126421].</rdfs:comment>
        <rdfs:label>IglC2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 471; NCBI Gene GI: 3191814; NCBI Protein GI: 56708721; NCBI Protein Accession: YP_170617; NCBITaxon: 177416</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011074 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011074">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011074</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with WbtI(G191V) protected mice against a relatively low-dose intraperitoneal challenge with LVS (F. tularensis subspecies holarctica live vaccine strain), but was less protective against a high-dose challenge [PubMed: 17768257].</rdfs:comment>
        <rdfs:label>WbtI</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 472; NCBI Gene GI: 5522688; NCBI Protein GI: 156502002; NCBI Protein Accession: YP_001428067; NCBITaxon: 458234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011075">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011075</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers have shown that mice that had been immunized with purified heat shock protein 60 (Hsp60, groEL) isolated from Francisella tularensis were protected against a subsequent challenge with some strains of the bacterium [PubMed: 15213156].</rdfs:comment>
        <rdfs:label>GroEL from Francisella tularensis</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 473; NCBI Protein GI: 282159959; NCBITaxon: 510831</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011076</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A 17-kDa lipoprotein, TUL4, of the facultative intracellular bacterium Francisella tularensis is one of several membrane proteins that induce an in vitro response in T cells from F. tularensis-primed humans.  When mice were immunized with S. typhimurium chi 4072(pTUL4-15), some animals showed an antibody response and a T-cell response to TUL4.  The present study demonstrated that the 17-kDa lipoprotein TUL4 of F. tularensis is involved in a protective immunity to tularemia [PubMed: 1612751].</rdfs:comment>
        <rdfs:label>TUL4</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 474; NCBI Protein GI: 148688; NCBITaxon: 263</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011077 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011077">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011077</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>C57BL/6 mice were vaccinated intranasally (i.n.) with the sodB(Ft) mutant and challenged i.n. with lethal doses of F. tularensis SchuS4. SodB(Ft) vaccinated mice following SchuS4 challenge exhibited significantly reduced bacterial burden in lungs, liver and spleen, regulated production of pro-inflammatory cytokines and less severe histopathological lesions compared to the LVS vaccinated mice. The sodB(Ft) vaccination induced a potent humoral immune response and protection against SchuS4 required both CD4 and CD8 T cells in the vaccinated mice [PubMed: 18692537].</rdfs:comment>
        <rdfs:label>SodB from F. tularensis SCHU S4</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 475; NCBI Gene GI: 3190713; NCBI Protein GI: 56707247; NCBI Protein Accession: YP_169143; NCBITaxon: 177416</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011078 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011078">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011078</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Anti-FopA MAbs protected 90% of nave C3H/HeN mice from lethal challenge with F. tularensis LVS when administered prophylactically as well as therapeutically [PubMed: 19176692].</rdfs:comment>
        <rdfs:label>FopA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 476; NCBI Gene GI: 4306351; NCBI Protein GI: 115315051; NCBI Protein Accession: YP_763774; NCBITaxon: 393011</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011079 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011079">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010760"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011079</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Anti-lpnA MAbs conferred significant, although not complete, protection of nave C3H/HeN mice from lethal challenge with F. tularensis LVS when administered therapeutically [PubMed: 19176692].</rdfs:comment>
        <rdfs:label>LpnA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 477; NCBI Gene GI: 3191792; NCBI Protein GI: 56708002; NCBI Protein Accession: YP_169898; NCBITaxon: 177416</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010829"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011080</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The gene encoding the full length cyst wall protein-2 (CWP2) from Giardia lamblia was subcloned into the pCDNA3 mammalian expression vector and stably introduced into S. typhimurium STM1.  Challenge infection with live Giardia muris cysts revealed that mice receiving the CWP2-encoding DNA vaccine were able to reduce cyst shedding by approximately 60% compared to control mice [PubMed: 17996337].</rdfs:comment>
        <rdfs:label>CWP2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 479; NCBI Gene GI: 5703171; NCBI Protein GI: 159120052; NCBI Protein Accession: XP_001710242; NCBITaxon: 50803</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011081 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011081">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011081</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Rats vaccinated with PD (hpd) cleared NT H. influenzae better after middle ear and pulmonary bacterial challenge, and chinchillas vaccinated with PD showed significant protection against NT H. influenzae-dependent acute otitis media. In a clinical trial involving children, PD was used as an antigenically active carrier protein in an 11-valent pneumococcal conjugate investigational vaccine; significant protection was achieved against acute otitis media not only caused by pneumococci but also caused by NT H. influenzae [PubMed: 18230042].</rdfs:comment>
        <rdfs:label>Hpd</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 480; NCBI Protein GI: 148971; NCBITaxon: 727</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011082 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011082">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011082</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In a chinchilla model of otitis media, initial screening of P5-fimbrin, delivered singly or in combination with either Freund&apos;s adjuvant or alum, indicated that augmented bacterial clearance from the nasopharynx, the middle ears, or both anatomical sites could be induced by parenteral immunization with P5-fimbrin combined with lipoprotein D, lipoprotein D alone, or the synthetic chimeric peptide LB1 (derived from P5-fimbrin), respectively [PubMed: 10338477].</rdfs:comment>
        <rdfs:label>OmpP5</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 482; NCBI Gene GI: 3430592; NCBI Protein GI: 68249712; NCBI Protein Accession: YP_248824; NCBITaxon: 281310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011083 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011083">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011083</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Purified rD15 was found to be highly immunogenic in mice, guinea pigs, and rabbits, and passive transfer of anti-rD15 antibodies protected infant rats from challenge with H. influenzae type b or type a in infant rat models of bacteremia [PubMed: 9284140].</rdfs:comment>
        <rdfs:label>D15</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 483; NCBI Gene GI: 3430379; NCBI Protein GI: 68249503; NCBI Protein Accession: YP_248615; NCBITaxon: 281310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011084 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011084">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011084</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Rabbit antibody prepared against P2 from one strain was cross-reactive with P2 isolated from the other two heterologous strains by Western blot. This antibody passively protected infant rats against type b Haemophilus infection caused by the homologous organism, but not against challenge by a strain with the heterologous 36,500 mol wt P2 protein [PubMed: 6603479].</rdfs:comment>
        <rdfs:label>OmpP2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 485; NCBI Gene GI: 3429565; NCBI Protein GI: 68248747; NCBI Protein Accession: YP_247859; NCBITaxon: 281310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011085 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011085">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011085</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Seoul virus (SEOV) is one of the four known hantaviruses causing hemorrhagic fever with renal syndrome (HFRS).  A replication-competent recombinant canine adenovirus type 2 expressing the Gc protein of SEOV (rCAV-2-Gc) in BALB/c mice induced complete protection against a intensive infectious challenge with ~1,000 50% infective doses (ID50) for SEOV strain CC-2 [PubMed: 20181748].</rdfs:comment>
        <rdfs:label>Gc</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 486; NCBI Protein GI: 284157806; NCBITaxon: 11608</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011086 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011086">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011086</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study used a deer mouse infection model to test the protective efficacy of genetic vaccine candidates for Sin Nombre (SN) virus that were known to provoke immunological responses in BALB/c mice.  Protective epitopes were localized in each of four overlapping cDNA fragments that encoded portions of the SN virus G1 glycoprotein antigen; the nucleocapsid gene also was protective [PubMed: 12075094].</rdfs:comment>
        <rdfs:label>G1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 487; NCBI Protein GI: 1113859; NCBITaxon: 37705</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011087 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011087">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011087</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study used a deer mouse infection model to test the protective efficacy of genetic vaccine candidates for Sin Nombre (SN) virus that were known to provoke immunological responses in BALB/c mice. Protective epitopes were localized in each of four overlapping cDNA fragments that encoded portions of the SN virus G1 glycoprotein antigen; the nucleocapsid gene (SNVsSgp1) also was protective [PubMed: 12075094].</rdfs:comment>
        <rdfs:label>SNVsSgp1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 489; NCBI Gene GI: 2943142; NCBI Protein GI: 38371726; NCBI Protein Accession: NP_941975; NCBITaxon: 37705</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011088 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011088">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011088</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>To investigate the ability of recombinant N (rN, nucleocapsid proteins) from different hantaviruses to elicit cross-protection, we immunized bank voles with rN from Puumala (PUUV), Topografov (TOPV), Andes (ANDV), and Dobrava (DOBV) viruses and subsequently challenged them with PUUV. All animals immunized with PUUV (PUUVsSgp1) and TOPV rN were completely protected [PubMed: 12050380].</rdfs:comment>
        <rdfs:label>PUUVsSgp1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 490; NCBI Gene GI: 2943083; NCBI Protein GI: 38371721; NCBI Protein Accession: NP_941984; NCBITaxon: 11604</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011089 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011089">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011089</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>To investigate the ability of recombinant N (rN, nucleocapsid proteins) from different hantaviruses to elicit cross-protection, we immunized bank voles with rN from Puumala (PUUV), Topografov (TOPV), Andes (ANDV), and Dobrava (DOBV) viruses and subsequently challenged them with PUUV. All animals immunized with PUUV and TOPV rN were completely protected [PubMed: 12050380].</rdfs:comment>
        <rdfs:label>N protein [Topografov virus]</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 491; NCBI Protein GI: 4757106; NCBITaxon: 83192</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011090 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011090">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011090</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers vaccinated hamsters with a vaccinia virus-vectored vaccine expressing the M and the S segments of Hantaan (HTN) virus and challenged them with HTN, Seoul (SEO), or Puumala (PUU) virus.  Study found that vaccinated hamsters, challenged with HTN or SEO virus, were neither viremic nor had evidence of virus in their lungs or kidneys [PubMed: 7666542].</rdfs:comment>
        <rdfs:label>M Segment</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 492; NCBI Protein GI: 1389703; NCBITaxon: 11599</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011091 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011091">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011091</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Passive transfer of spleen cells from mice immunized with rNP (HTNVsSgp1) conferred partial protection or prolongation of time to death from fatal Hantaan virus infection in suckling mice which were challenged with Hantaan virus at 40 LD50 (survival rate: 43%) or 4 LD50 (survival rate: 43%) [PubMed: 8517793].</rdfs:comment>
        <rdfs:label>HTNVsSgp1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 493; NCBI Gene GI: 2943078; NCBI Protein GI: 38371711; NCBI Protein Accession: NP_941977; NCBITaxon: 11599</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011092 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011092">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010768"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011092</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Nonreplicating adenovirus (Ad) vectors that express Andes hantavirus (ANDV) nucleocapsid protein (AdN, ANDVsSgp1) or glycoproteins (AdG(N) and AdG(C)) were constructed . When administered once, all three Ad vectors, individually or in combination, elicited a robust immune response that protected Syrian hamsters from a lethal ANDV infection that mimics the pulmonary disease seen in humans. No vaccinated animal died, and there were no obvious clinical signs of disease [PubMed: 19403663].</rdfs:comment>
        <rdfs:label>ANDVsSgp1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 494; NCBI Gene GI: 991232; NCBI Protein GI: 19744950; NCBI Protein Accession: NP_604471; NCBITaxon: 46607</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011093">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010781"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011093</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study compared a current HBV vaccine that contains recombinant hepatitis B surface antigen HBsAg) adsorbed to alum in chimpanzees, with two novel vaccine strategies that have proven superior to the current vaccine in mice. All animals receiving either control or CpG-containing subunit vaccines at 0 and 4 weeks attained titers of HBsAg-specific antibody (anti-HBs) considered protective (&gt; or =10 mIU/ml) and were indeed protected from challenge at 8 weeks with 10(3.5) 50% chimp infectious doses (CID(50)) of intravenous HBV [PubMed: 16428890].</rdfs:comment>
        <rdfs:label>Hepatitis B surface antigen</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 495; NCBI Protein GI: 128168861; NCBITaxon: 10407</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011094 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011094">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010781"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011094</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The immunological protection of pVAX-PS, a DNA vaccine, was assessed in the tree shrews model. pVAX-PS was constructed by inserting the gene encoding the middle (pre-S2 plus S) envelope protein of HBV into a plasmid vector pVAX1.  Results indicated that pVAX-PS immunization could induce remarkable humoral immune response and prevent the experimental tree shrews from infection of HBV [PubMed: 12932306].</rdfs:comment>
        <rdfs:label>PreS2 middle surface protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 496; NCBI Protein GI: 113207330; NCBITaxon: 10407</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011095 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011095">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010781"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011095</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunisation with a plasmid encoding the DHBV large (L) envelope protein (HBVgp2 pre-S1/pre-S2/S) induced a strong, specific, highly neutralising and long-lasting anti-preS humoral response in uninfected ducks. Importantly, maternal antibodies elicited by such DNA immunisation were vertically transmitted and protected progeny against viral challenge [PubMed: 12531335].</rdfs:comment>
        <rdfs:label>HBVgp2 pre-S1/pre-S2/S</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 497; NCBI Gene GI: 944569; NCBI Protein GI: 77680739; NCBI Protein Accession: YP_355333; NCBITaxon: 10407</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011096">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010834"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011096</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The herpes simplex virus type 2 (HSV-2) glycoprotein D (gD2) gene was inserted into an intergenic site in the unique short region of the Oka VZV genome. Expression of gD2 in cells infected with the recombinant Oka strain VZV (ROka-gD2) was confirmed by antibody staining of fixed cells and by immunoblot analysis.  Forty days after the third inoculation, guinea pigs were challenged intravaginally with HSV-2. Inoculation of guinea pigs with ROka-gD2 significantly reduced the severity of primary HSV-2 infection (P &lt; 0.001) [PubMed: 7494331].</rdfs:comment>
        <rdfs:label>US6 from Herpes simplex virus type 1 and 2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 499; NCBI Gene GI: 1487358; NCBI Protein GI: 9629336; NCBI Protein Accession: NP_044536; NCBITaxon: 10310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011097">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010834"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011097</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The present study evaluated the modulatory functions of salbutamol co-administered with DNA vaccine expressing gB (UL27) of herpes simplex virus (HSV) via intranasal (i.n.) route.  The enhanced immune responses caused by co-administration of salbutamol provided effective and rapid responses to HSV mucosal challenge, thereby conferring prolonged survival and reduced inflammation against viral infection [PubMed: 19641376].</rdfs:comment>
        <rdfs:label>UL27 from Herpes simplex virus type 2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 500; NCBI Protein GI: 1869850; NCBITaxon: 10310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011098 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011098">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010834"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011098</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice receiving a glycoprotein D1 (gD1, US5) DNA vaccine alone were 80% protected against a subsequent HSV-1 challenge.  Results also indicate that the administration of NLX as an adjuvant improved protective immunity against HSV-1 [PubMed: 19174474].</rdfs:comment>
        <rdfs:label>US5</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 501; NCBI Gene GI: 2703406; NCBI Protein GI: 9629447; NCBI Protein Accession: NP_044668; NCBITaxon: 10298</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011099">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010834"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011099</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study demonstrated that recombinant Listeria monocytogenes (Lm) expressing the H-2K(b) glycoprotein B (gB, UL27)(498-505) peptide from HSV-1 triggers a robust CD8 T cell response to this Ag resulting in protective immunity to HSV infection in mice [PubMed: 17404252].</rdfs:comment>
        <rdfs:label>UL27 from Herpes simplex virus type 1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 502; NCBI Gene GI: 2703455; NCBI Protein GI: 9629408; NCBI Protein Accession: NP_044629; NCBITaxon: 10298</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010834"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011100</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Particle-mediated DNA vaccination of mice with a DNA plasmid-encoding ICP27 resulted in the induction of ICP27-specific IFN-gamma and TNF-alpha production in Balb/c mice.  When the DNA vaccine was supplemented with as little as 50ng of a vector encoding the A and B subunits of the Escherichia coli heat labile enterotoxin (LT), animals were profoundly protected from morbidity and mortality [PubMed: 16621198].</rdfs:comment>
        <rdfs:label>ICP27 from Herpes simplex virus type 2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 503; NCBI Protein GI: 124181; NCBITaxon: 10315</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011101">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010834"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011101</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Epitopes from the ICP27 (H1, H2), glycoprotein B (gB) and glycoprotein D (gD) proteins of HSV-1 were attached to either the J TCBL/ICBL or the G TCBL/ICBL. The JH1, JH2, JgB and JgD vaccines elicited DTH responses without antibody but conferred protection upon lethal challenge with HSV [PubMed: 15569635].</rdfs:comment>
        <rdfs:label>ICP27 from Herpes simplex virus type 1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 504; NCBI Protein GI: 75812153; NCBITaxon: 10298</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011102 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011102">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010834"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011102</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In two experiments, mice immunised with phage displaying a single epitope of gG2 (US4) were protected against challenge with a lethal dose of whole HSV-2 [PubMed: 10725197].</rdfs:comment>
        <rdfs:label>US4</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 505; NCBI Gene GI: 1487356; NCBI Protein GI: 9629334; NCBI Protein Accession: NP_044534; NCBITaxon: 10310</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011103">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010834"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011103</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protection against a lethal intraperitoneal challenge of HSV-1 (5 x 10(4) pfu) with gC (UL44) or gE plasmid vaccination could be demonstrated if the inoculating dose of DNA was 250 microg.  All mice immunized with vaccinia recombinants expressing either gC or gE survived HSV-1 challenge [PubMed: 9728527].</rdfs:comment>
        <rdfs:label>UL44 from Herpes simplex virus type 1 and 2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 506; NCBI Gene GI: 2703410; NCBI Protein GI: 9629425; NCBI Protein Accession: NP_044646; NCBITaxon: 10298</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011104">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010834"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011104</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protection against a lethal intraperitoneal challenge of HSV-1 (5 x 10(4) pfu) with gC or gE (US8) plasmid vaccination could be demonstrated if the inoculating dose of DNA was 250 microg. All mice immunized with vaccinia recombinants expressing either gC or gE survived HSV-1 challenge [PubMed: 9728527].</rdfs:comment>
        <rdfs:label>US8</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 507; NCBI Gene GI: 2703448; NCBI Protein GI: 9629449; NCBI Protein Accession: NP_044670; NCBITaxon: 10298</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011105 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011105">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010786"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011105</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E7</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers combined the HPV16 E7 peptide(38-61) with a murine IgG heavy chain constant region to construct a chimeric protein compound.  The chimeric vaccine candidate was able to effectively protect mice against the challenge of HPV16-positive tumor cells, and to eradicate HPV16-expressing tumors in mice [PubMed: 15661238].</rdfs:comment>
        <rdfs:label>HPV E7</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 509; NCBI Gene GI: 1489079; NCBI Protein GI: 9627105; NCBI Protein Accession: NP_041326; NCBITaxon: 333760</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011106 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011106">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010786"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011106</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L2</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Antibody responses of mice (n = 120) and rabbits (n = 23) to vaccination with HPV-16 amino-terminal L2 polypeptides or multitype L2 fusion proteins were compared.  11-200 x 3 formulated in GPI-0100 adjuvant or alum with 1018 ISS protected mice against HPV-16 challenge (reduction in HPV-16 infection vs phosphate-buffered saline control, P &lt; .001) 4 months after vaccination as well as HPV-16 L1 VLPs [PubMed: 19470949].</rdfs:comment>
        <rdfs:label>HPV L2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 510; NCBI Gene GI: 1489081; NCBI Protein GI: 9627107; NCBI Protein Accession: NP_041331; NCBITaxon: 333760</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011107 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011107">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010786"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011107</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E6</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>C57BL/6 mice vaccinated with pNGVL4a-E6/opt are able to generate potent protective and therapeutic antitumor effects against challenge with E6-expressing tumor cell line, TC-1 of HPV [PubMed: 16649071].</rdfs:comment>
        <rdfs:label>HPV E6</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 511; NCBI Gene GI: 1489078; NCBI Protein GI: 9627104; NCBI Protein Accession: NP_041325; NCBITaxon: 333760</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011108 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011108">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010786"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011108</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L1</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>rAAV5, -8 and -9 vectors expressing an HPV16 L1/E7 fusion gene were generated and applied intranasally for combined prophylactic and therapeutic vaccination of mice.  Vaccination with the rAAV vectors led to a significant protection of animals against a challenge with different HPV tumour cell lines [PubMed: 20032542].</rdfs:comment>
        <rdfs:label>HPV L1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 512; NCBI Gene GI: 1489082; NCBI Protein GI: 9627108; NCBI Protein Accession: NP_041332; NCBITaxon: 333760</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011109 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011109">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010810"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011109</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The DNA vaccine pIHNw-G encodes the glycoprotein of the fish rhabdovirus infectious hematopoietic necrosis virus (IHNV). Vaccine performance in rainbow trout was measured 3, 6, 13, 24, and 25 months after vaccination. At three months all fish vaccinated with 0.1 microg pIHNw-G had detectable neutralizing antibody (NAb) and they were completely protected from lethal IHNV challenge with a relative percent survival (RPS) of 100% compared to control fish [PubMed: 16154239].</rdfs:comment>
        <rdfs:label>G glycoprotein from Infectious Hematopoietic Necrosis Virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 513; NCBI Gene GI: 1489848; NCBI Protein GI: 9628086; NCBI Protein Accession: NP_042679; NCBITaxon: 11290</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011110 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011110">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011110</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice were immunized intranasally with an adjuvant (cholera toxin B subunit containing 0.2% of the whole toxin)-combined with A or B virus recombinant NP. The NP-immune mice, when challenged intranasally with a sublethal dose of the virus 3 wk after immunization, had accelerated virus clearance from the nasal site in both an influenza type-specific and a nonspecific manner, as shown by the protection from high morbidity from the second day after challenge [PubMed: 8621928].</rdfs:comment>
        <rdfs:label>NP from Influenza B virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 514; NCBI Gene GI: 956539; NCBI Protein GI: 8486155; NCBI Protein Accession: NP_056661; NCBITaxon: 11520</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011111 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011111">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011111</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice were immunized intranasally with an adjuvant (cholera toxin B subunit containing 0.2% of the whole toxin)-combined with A or B virus recombinant NP. The NP-immune mice, when challenged intranasally with a sublethal dose of the virus 3 wk after immunization, had accelerated virus clearance from the nasal site in both an influenza type-specific and a nonspecific manner, as shown by the protection from high morbidity from the second day after challenge [PubMed: 8621928].</rdfs:comment>
        <rdfs:label>NP from Influenza A virus H3N2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 515; NCBI Protein GI: 3722159; NCBITaxon: 41857</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011112 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011112">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011112</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Skin and mucosal vaccination provided complete protection from clinical signs of infection with ponies subjected to a challenge infection of Equine influenza virus, while skin vaccination provided partial protection; DNA vaccination provided partial protection from viral shedding [PubMed: 10403592].</rdfs:comment>
        <rdfs:label>HA from Equine influenza virus H3N8</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 516; NCBI Protein GI: 404517; NCBITaxon: 31660</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011113 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011113">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011113</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A nonpathogenic vector of the cytoplasmic domain of the VSV G protein and expressing influenza virus HA (derived from Influenza A virus (A/WSN/1933(H1N1))) provides complete protection from lethal influenza virus challenge after intranasal administration. A second vector with VSV G deleted and expressing HA (DeltaG-HA) is also protective and nonpathogenic and has the advantage of not inducing neutralizing antibodies to the vector itself [PubMed: 10196265].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/WSN/1933(H1N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 518; NCBI Protein GI: 324200; NCBITaxon: 382835</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011114 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011114">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011114</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A recombinant baculovirus expressing the hemagglutinin gene of the influenza virus, A/PR/8/34 (H1N1), under the control of the chicken beta-actin promoter, was constructed.  Protection from a lethal challenge of the influenza virus was achieved by intranasal immunization of the recombinant baculovirus [PubMed: 12874198].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Puerto Rico/8/1934(H1N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 519; NCBI Protein GI: 126599271; NCBITaxon: 211044</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011115 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011115">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011115</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Two cyclic peptide analogues corresponding to residues 139-146 (site A) of influenza A virus haemagglutinin (strain X31) were synthesized.  When OF1 mice were immunized with cyclic peptides, approximately 80% of the animals were protected against an intranasal challenge with influenza virus [PubMed: 2396470].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Aichi/2/1968(H3N2)), (X31)</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 520; NCBI Protein GI: 324132; NCBITaxon: 387139</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011116 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011116">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011116</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice and ferrets were immunised with two doses of the split virus vaccine (12-24 microg haemagglutinin derived from Influenza A virus (A/chicken/Italy/13474/99(H7N1))) with or without aluminium hydroxide adjuvant and challenged 3 weeks after second dose with the highly pathogenic A/chicken/Italy/13474/99 (H7N1) virus.  The vaccine induced significant protection from disease after challenge with the wild-type virus. In the murine lethal challenge model, vaccination effectively prevented death and, furthermore, formulation with adjuvant reduced excessive weight loss and viral shedding [PubMed: 19453487].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/chicken/Italy/13474/99(H7N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 521; NCBI Protein GI: 32261025; NCBITaxon: 199442</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011117 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011117">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011117</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization and challenge experiments in mice indicated that even though vaccination with the recombinant HA vaccinia viruses derived from Influenza B virus (Strain B/England/222/82) induced different levels of cross-reactive neutralizing antibodies, mice vaccinated with either recombinant vaccinia virus were protected from infection with either subpopulation of influenza virus [PubMed: 3318092].</rdfs:comment>
        <rdfs:label>HA from Influenza B virus (Strain B/England/222/82)</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 522; NCBI Protein GI: 122955; NCBITaxon: 11527</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011118 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011118">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011118</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice vaccinated with a recombinant VLP vaccine from both influenza A H5N1 clade 1 and clade 2 isolates (Influenza A virus (A/duck/Badung-Bali/05/2005(H5N1))) with pandemic potential were protected against challenge with lethal reassortant viruses expressing the H5N1 HA and NA, regardless if the H5N1 clade was homologous or heterologous to the vaccine [PubMed: 18231588].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/duck/Badung-Bali/05/2005(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 523; NCBI Protein GI: 190344179; NCBITaxon: 389226</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011119">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011119</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A targeted fusion protein based on the CTA1-DD adjuvant and containing tandem repeats of the matrix protein 2 (M2e) ectodomain epitope derived from Influenza A virus (A/Puerto Rico/8/34(H1N1)), CTA1-3M2e-DD, confers strong protective immunity against a potentially lethal challenge infection with influenza virus in mice. The formulation was highly effective for mucosal immunizations and promoted high M2e-specific serum IgG and mucosal IgA antibody titers and an hitherto unknown anti-M2e CD4 T cell immunity [PubMed: 18243429].</rdfs:comment>
        <rdfs:label>M2 from Influenza A virus (A/Puerto Rico/8/34(H1N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 524; NCBI Gene GI: 956528; NCBI Protein GI: 56583270; NCBI Protein Accession: NP_040979; NCBITaxon: 211044</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011120</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination with HA-VRP derived from Influenza A virus (A/Hong Kong/1/68(H3N2)) did not strongly stimulate either neutralizing or IgG1 antibodies but did induce IgG2a antibodies. Expression of IgG2a antibodies in this context correlated with clearance of virus and increased protection against lethal influenza challenge [PubMed: 16960108].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Hong Kong/1/68(H3N2))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 525; NCBI Protein GI: 16960108; NCBITaxon: 10090</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011121">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011121</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers report that a DNA vaccine encoding hemagglutinin from the index human influenza isolate A/HK/156/97 provides immunity against H5N1 infection of mice [PubMed: 9971791].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/environment/Hong Kong/156/1997(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 527; NCBI Protein GI: 269826115; NCBITaxon: 680785</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011122 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011122">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011122</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A simian adenovirus 24 (AdC7) vector expressing the influenza A/Puerto Rico/8/34 NP was tested for its efficacy in protecting BALB/c mice against two H5N1 strains.  When tested in a mouse challenge model, there was a significantly improved survival rate following challenge with the Vietnam/1203/04 strain of H5N1 that has caused human outbreaks [PubMed: 17728024].</rdfs:comment>
        <rdfs:label>NP from Influenza A virus (A/Puerto Rico/8/34(H1N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 528; NCBI Gene GI: 956531; NCBI Protein GI: 8486130; NCBI Protein Accession: NP_040982; NCBITaxon: 211044</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011123 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011123">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011123</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The protective effect of neuraminidase (NA) was studied in a mouse protection test using isolated neuraminidase of A2/Aichi/68(H3N2) virus and the complete recombinant virus A/eq(Heq-1)-HK(N2) as antigens. Immunized mice were protected against A2/Aichi(H3N2) challenge virus; however, the protection rate was low in comparison to animals immunized with comparable amounts of the complete A2/68(H3N2) virus9 [PubMed: 1126575].</rdfs:comment>
        <rdfs:label>NA from Influenza A virus (A/Aichi/2/1968(H3N2))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 530; NCBI Protein GI: 46401580; NCBITaxon: 387139</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011124 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011124">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011124</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In mouse models of influenza infection, the vaccines derived from Influenza A virus (A/Solomon Islands/3/2006(H1N1)) hemagglutinin elicit robust antibody responses that mitigate disease and protect mice from lethal challenge [PubMed: 18493310].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Solomon Islands/3/2006(H1N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 531; NCBI Protein GI: 156123416; NCBITaxon: 464623</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011125 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011125">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011125</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Results indicated that two doses of 10 microg of pCAGGoptiHA derived from Influenza A virus (A/Goose/Guangdong/1/96(H5N1)) could induce complete protection in chickens against H5 lethal virus challenge [PubMed: 17451817].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Goose/Guangdong/1/96(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 532; NCBI Gene GI: 3654620; NCBI Protein GI: 73852955; NCBI Protein Accession: YP_308669; NCBITaxon: 93838</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011126 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011126">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011126</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The inoculation of HA vaccine prepared from influenza viruses A/Yamagata/120/86 (H1N1) or A/Fukuoka/C29/85 (H3N2) together with CTB provided partial protection against PR-8 infection in Balb/c mice [PubMed: 2781859].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Yamagata/120/1986(H1N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 533; NCBI Protein GI: 221344; NCBITaxon: 379740</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011127 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011127">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011127</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The inoculation of HA vaccine prepared from influenza viruses A/Yamagata/120/86 (H1N1) or A/Fukuoka/C29/85 (H3N2) together with CTB provided partial protection against PR-8 infection in Balb/c mice [PubMed: 2781859].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Fukuoka/C29/85(H3N2))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 534; NCBI Protein GI: 221306; NCBITaxon: 62549</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011128 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011128">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011128</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protection against a lethal influenza B virus infection was examined in BALB/c mice immunized with plasmid DNAs encoding hemagglutinin (HA), neuraminidase (NA and NB) and nucleoprotein (NP) from the B/Ibaraki/2/85 virus.  Both HA and NA DNAs conferred complete protection against the lethal challenge in all the tested mouse strains [PubMed: 11163667].</rdfs:comment>
        <rdfs:label>HA from Influenza B virus (B/Ibaraki/2/85)</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 535; NCBI Protein GI: 122959; NCBITaxon: 107411</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011129 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011129">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011129</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protection against a lethal influenza B virus infection was examined in BALB/c mice immunized with plasmid DNAs encoding hemagglutinin (HA), neuraminidase (NA and NB) and nucleoprotein (NP) from the B/Ibaraki/2/85 virus.  Both HA and NA DNAs conferred complete protection against the lethal challenge in all the tested mouse strains [PubMed: 11163667].</rdfs:comment>
        <rdfs:label>NA from Influenza B virus (B/Ibaraki/2/85)</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 536; NCBI Protein GI: 53829726; NCBITaxon: 107411</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011130 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011130">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011130</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Viral challenge studies showed that live BacHA derived from Influenza A virus (A/Indonesia/CDC669/2006(H5N1)) was able to provide 100% protection against 5 50% mouse lethal doses (MLD(50)) of homologous (clade 2.1) and heterologous (clade 1) H5N1 [PubMed: 20071572].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Indonesia/CDC669/2006(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 537; NCBI Protein GI: 113497156; NCBITaxon: 400828</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011131 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011131">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011131</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Viral challenge studies showed that live BacHA derived from Influenza A virus (A/Indonesia/CDC594/2006(H5N1)) was able to provide 100% protection against 5 50% mouse lethal doses (MLD(50)) of homologous (clade 2.1) and heterologous (clade 1) H5N1 [PubMed: 20071572].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Indonesia/CDC594/2006(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 538; NCBI Protein GI: 113495780; NCBITaxon: 400810</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011132 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011132">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011132</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A DNA vaccine encoding HA (from Influenza A virus (A/Hawaii/01/1991(H3N2))), NP and M1 (from a 1989 strain) protected ferrets better against challenge with the antigenic drift variant A/Georgia/03/93 than did the inactivated vaccine from the 1992-93 influenza season. Researchers report that the same DNA vaccine protected ferrets against a second, further divergent, drift variant (A/Johannesburg/33/94) [PubMed: 9234535].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Hawaii/01/1991(H3N2))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 539; NCBI Protein GI: 110313990; NCBITaxon: 387158</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011133 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011133">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011133</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later. The mice immunized with HA plasmid once and the NA plasmid twice survived 100% [PubMed: 19067149].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/chicken/Henan/12/2004(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 540; NCBI Protein GI: 61698018; NCBITaxon: 319102</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011134 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011134">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011134</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later. The mice immunized with NP plasmid showed 60-80% survival rate with at least three immunizations.  The mixture of M1 and NP plasmids protected 95% of the mice against the homologous virus, and 80% of the mice against a challenge with heterologous H1N1 (PR8) virus [PubMed: 19067149].</rdfs:comment>
        <rdfs:label>NP from Influenza A virus (A/chicken/Henan/12/2004(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 541; NCBI Protein GI: 61698066; NCBITaxon: 319102</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011135 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011135">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011135</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later.  The mice immunized with HA plasmid once and the NA plasmid twice survived 100% [PubMed: 19067149].</rdfs:comment>
        <rdfs:label>NA from Influenza A virus (A/chicken/Henan/12/2004(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 542; NCBI Protein GI: 61698053; NCBITaxon: 319102</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011136 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011136">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011136</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later.  The mice immunized with M1 plasmid survived 25% with five immunizations.  The mixture of M1 and NP plasmids protected 95% of the mice against the homologous virus, and 80% of the mice against a challenge with heterologous H1N1 (PR8) virus [PubMed: 19067149].</rdfs:comment>
        <rdfs:label>M1 from Influenza A virus (A/chicken/Henan/12/2004(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 543; NCBI Protein GI: 61698034; NCBITaxon: 319102</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011137 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011137">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011137</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination with ptPAs/NP derived from Influenza A virus (A/chicken/Hubei/489/2004(H5N1)) efficiently cleared the homologous H5N1 influenza virus in the infected lungs and induced partial cross-protection against heterologous, highly pathogenic H5N1 strains in mice [PubMed: 18789973].</rdfs:comment>
        <rdfs:label>NP from Influenza A virus (A/chicken/Hubei/489/2004(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 544; NCBI Protein GI: 55233233; NCBITaxon: 298603</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011138 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011138">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011138</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers evaluated the immunogenicity and efficacy of a panel of flagellin-based hemagglutinin (HA) globular head fusion vaccines in inbred mice. The HA globular head of these vaccines was derived from the A/Vietnam/1203/04 (VN04; H5N1) HA molecule. Results show that replacement of domain D3 of flagellin with the VN04 HA globular head creates a highly effective vaccine that elicits protective HAI titers which protect mice against disease and death in a lethal challenge model with H5 VN virus [PubMed: 19654064].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Viet Nam/1203/2004(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 545; NCBI Protein GI: 159144921; NCBITaxon: 284218</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011139 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011139">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011139</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Using reverse genetics, we constructed a recombinant NDV expressing an H9 AIV hemagglutinin (HA) from an H9N2 field isolate, A/Chicken/ Shandong/2/2007.  When tested, 90% of chickens were protected from clinical disease, mortality, and virus shedding against challenge with homologous H9N2 AIV [PubMed: 20521648].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/chicken/Guangdong/02/2007(H9N2))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 546; NCBI Protein GI: 206812650; NCBITaxon: 563925</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011140 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011140">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011140</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with DNA/rAd5 vaccines encoding HA derived from Influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1)) conferred protection in ferrets against a stringent virus challenge [PubMed: 20352112].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 547; NCBI Nucleotide GI: 46578137; NCBI Protein GI: 46578138; NCBI Protein Accession: AAS65615.2; NCBITaxon: 266827</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011141 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011141">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011141</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>All  specific-pathogen-free chickens immunized with (vFP89) expressing the native hemagglutinin (HA) gene from H5N8 A/turkey/ Ireland/1378/83 were clinically protected from HPAI challenge [PubMed: 20521642].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/turkey/Ireland/1378/1983(H5N8))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 549; NCBI Protein GI: 115279333; NCBITaxon: 380285</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011142 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011142">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011142</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>All specific-pathogen-free chickens immunized with (vFP2211) expressing a modified synthetic HA gene from H5N1 A/chicken/Indonesia/7/2003 were clinically protected from HPAI challenge [PubMed: 20521642].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/chicken/Indonesia/7/2003(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 550; NCBI Protein GI: 129282887; NCBITaxon: 430432</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011143 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011143">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011143</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A neutralizing monoclonal antibody (mAb) 9F4 against the hemagglutinin (HA) of the influenza A/chicken/hatay/2004 H5N1 virus was generated.   MAb 9F4 was found to be protective, both prophylactically and therapeutically, against lethal viral challenge of mice [PubMed: 20519402].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/Hatay/2004/(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 551; NCBI Protein GI: 56311402; NCBITaxon: 303316</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011144 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011144">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011144</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Chickens immunized with attenuated Salmonella strains expressing the hemagglutinin (HA1) gene from a highly pathogenic avian influenza (HPAI) H5N1 (A/whooper swan/Mongolia/3/2005) demonstrated a statistically significant increase in survival compared to control groups [PubMed: 20406663].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/whooper swan/Mongolia/3/05(H5N1))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 553; NCBI Protein GI: 81687119; NCBITaxon: 344596</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011145 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011145">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010783"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011145</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers constructed a recombinant pseudotype baculovirus encoding the JEV envelope (E) protein and demonstrated that it could elicit high protective immunity in mice.  Intramuscular injections of BV-G-E at various doses into mice produced higher levels of JEV-specific neutralizing antibodies, IFN-gamma and better protective efficacy against a lethal challenge with JEV than that of pc-E. Furthermore, BV-G-E could elicit a higher level of cellular immunity response and provide equal protective efficacy against JEV challenge compared to inactivated vaccine [PubMed: 19006097].</rdfs:comment>
        <rdfs:label>Envelope protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 554; NCBI Protein GI: 16445023; NCBITaxon: 11072</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010783"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011146</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers established a simple and effective method for DNA immunization against Japanese encephalitis virus (JEV) infection with plasmids encoding the viral PrM and E proteins and colloidal gold.   After being inoculated twice, BALB/c mice were found to resist challenge with 100,000 times the 50% lethal dose (LD(50)) of JEV (Beijing-1 strain) even when immunized with a relatively small dose of 0.5 micro g of plasmid DNA [PubMed: 12634382].</rdfs:comment>
        <rdfs:label>PrM from Japanese encephalitis virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 555; NCBI Protein GI: 90019439; NCBITaxon: 11072</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011147 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011147">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010783"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011147</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Balb/c mice and swine vaccinated with TK(-)/gG(-)/NS1(+) expressing NS1 protein of JEV could confer protective immunity against lethal challenge of the virulent PRV Ea strain and develop a good humoral and cellular immune response against JEV [PubMed: 15121294].</rdfs:comment>
        <rdfs:label>NS1 from Japanese encephalitis virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 556; NCBI Protein GI: 18418672; NCBITaxon: 11072</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011148 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011148">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010783"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011148</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers constructed plasmid DNAs encoding JE virus proteins.  Cytotoxic T lymphocytes (CTLs) were induced by NS3 in a mouse model.  Three immunizations with pUJENS3 provided a 50% partial protection from a lethal dose of JE virus [PubMed: 12922097].</rdfs:comment>
        <rdfs:label>NS3</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 557; NCBI Protein GI: 27696332; NCBITaxon: 11072</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011149 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011149">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010783"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011149</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers constructed plasmid DNAs encoding JE virus proteins. Cytotoxic T lymphocytes (CTLs) were induced by NS5 in a mouse model. Three immunizations with pUJENS5 provided a 57% partial protection from a lethal dose of JE virus [PubMed: 12922097].</rdfs:comment>
        <rdfs:label>NS5</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 558; NCBI Protein GI: 158702649; NCBITaxon: 11072</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010783"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011150</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A cDNA clone representing the genome of structural proteins of Japanese encephalitis virus (JEV) was inserted into the thymidine kinase gene of vaccinia virus strains LC16mO and WR.  Inoculation of rabbits with the infectious recombinant vaccinia virus resulted in rapid production of antiserum specific for the PreM and E glycoproteins of JEV.  Mice vaccinated with the recombinant produced JEV-neutralizing antibodies and were resistant to challenge with JEV [PubMed: 2159544].</rdfs:comment>
        <rdfs:label>PreM</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 559; NCBI Protein GI: 14600066; NCBITaxon: 11072</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011151 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011151">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010763"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011151</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccine efficacy trials in guinea pigs indicated that the nucleoprotein is capable of eliciting a protective immune response against a lethal dose of Lassa virus. Ninety-four percent of the animals vaccinated with V-LSN survived a Lassa virus challenge in which only 14% of unvaccinated animals and 39% of animals vaccinated with the New York Board of Health (NYBH) strain of vaccinia virus survived [PubMed: 2741340].</rdfs:comment>
        <rdfs:label>LASVsSgp1 nucleoprotein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 560; NCBI Gene GI: 956584; NCBI Protein GI: 23343510; NCBI Protein Accession: NP_694869; NCBITaxon: 11620</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011152 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011152">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011152</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice were immunized with a vaccine expressing the 78kDa (GRP-78) antigen of Leishmania donovani. Challenge infection was given intracardially after 2 weeks of second booster. A significant decrease in parasite burden was seen in vaccinees over the infected controls on all post challenge days and was found that maximum protection was provided by 78kDa+rIL-12 vaccine.  It was highly immunogenic as depicted by the reduction in parasite load (71-94.8%) [PubMed: 20093205].</rdfs:comment>
        <rdfs:label>GRP-78</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 561; NCBI Protein GI: 16797868; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011153 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011153">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011153</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study results show that a single intraperitoneal administration of the A2-recombinant L. tarentolae strain expressing the Leishmania donovani A2 antigen protects BALB/c mice against L. infantum challenge and that protective immunity is associated with high levels of IFN-gamma production prior and after challenge [PubMed: 19818721].</rdfs:comment>
        <rdfs:label>A2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 563; NCBI Protein GI: 30385439; NCBITaxon: 5671</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011154 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011154">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011154</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani.  Results demonstrated that liposomal LD31 (ATP synthase alpha chain) reduced parasite burden by 74%-77% [PubMed: 19503834].</rdfs:comment>
        <rdfs:label>F1-ATPase</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 564; NCBI Protein GI: 722242; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011155 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011155">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011155</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani. Results demonstrated that liposomal LD51 (beta-tubulin) reduced parasite burden by 72%-75% [PubMed: 19503834].</rdfs:comment>
        <rdfs:label>Beta-tubulin</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 565; NCBI Protein GI: 262233287; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011156 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011156">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011156</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani. Results demonstrated that liposomal LD72 (Hsp70) reduced parasite burden by 65%-67% [PubMed: 19503834].</rdfs:comment>
        <rdfs:label>Hsp70</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 566; NCBI Protein GI: 281426606; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011157 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011157">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011157</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>KMP-11 DNA vaccination alone in an experimental BALB/c mice model showed significant potential in terms of resolution of splenic and hepatic parasite burden against virulent LD challenge.  KMP-11 DNA immunization significantly protects against L. donovani infection [PubMed: 19162111].</rdfs:comment>
        <rdfs:label>KMP-11</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 567; NCBI Protein GI: 7579896; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011158 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011158">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011158</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study showed that cationic distearoyl phosphatidylcholine (DSPC) liposomes, when used as vaccine adjuvant with the immunodominant 63-kDa glycoprotein (gp63, mspC) of Leishmania donovani promastigotes, induced significant protection against progressive visceral leishmaniasis in susceptible BALB/c mice. gp63 used without adjuvant elicited partial protection but in association with liposomes exhibited marked resistance in both the livers and spleens of the mice challenged 10 days after the last vaccination [PubMed: 18195029].</rdfs:comment>
        <rdfs:label>MspC</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 568; NCBI Protein GI: 21954466; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011159 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011159">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011159</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>An expression plasmid encoding both p35 and p40 subunits of IL-12 when co-administered with a recombinant open-reading frame (rORFF) gene from the LD1 locus of Leishmania donovani induces significant protection with around 82% protection in both liver and spleen of BALB/c mice when challenged with L. donovani [PubMed: 16413950].</rdfs:comment>
        <rdfs:label>ORFF</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 569; NCBI Protein GI: 703122; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011160 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011160">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011160</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization of mice with recombinant BT1 proteins (a biopterin transporter) from multigenic LD1 locus on chromosome 35 of L. donovani conferred partial protection against challenge with Leishmania donovani in a BALB/c mice [PubMed: 15357215].</rdfs:comment>
        <rdfs:label>BT1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 570; NCBI Protein GI: 703123; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011161 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011161">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011161</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Experimental infection of immunized BALB/c mice demonstrated that the VR1012-NH36 DNA vaccine derived from the nucleoside hydrolase gene (NH) of L. donovani induced an 88% reduction in L. chagasi parasite load and a 65% reduction in L. mexicana lesion size [PubMed: 15664920].</rdfs:comment>
        <rdfs:label>NH</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 571; NCBI Protein GI: 19697561; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011162">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010832"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011162</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study demonstrated for the first time that a recombinant stage-specific hydrophilic surface protein of Leishmania donovani, recombinant hydrophilic acylated surface protein B1 (HASPB1), is able to confer protection against experimental challenge with L. donovani in BALB/c mice [PubMed: 11120835].</rdfs:comment>
        <rdfs:label>L. donovani HASPB1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 572; NCBI Protein GI: 51847753; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011163 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011163">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010769"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011163</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Nonhuman primates (cynomolgus macaques) were inoculated with VEE replicons expressing MBGV GP and/or NP and challenged with MGBV.  MBGV NP afforded incomplete (partial) protection, sufficient to prevent death but not disease in two of three macaques [PubMed: 9813200 ].</rdfs:comment>
        <rdfs:label>NP from Lake Victoria marburgvirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 573; NCBI Protein GI: 332181; NCBITaxon: 11269</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011164 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011164">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010804"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011164</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant fowl poxviruses (rFPVs) were constructed to express genes from serotype 1 Marek&apos;s disease virus (MDV, Gallid herpesvirus 2).  rFPV/gB1 expressing MDV040 conferred 42% protection in maternal antibody-positive chickens when challenged with highly virulent MDV isolates [PubMed: 14562881].</rdfs:comment>
        <rdfs:label>MDV040</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 574; NCBI Gene GI: 4811501; NCBI Protein GI: 125745079; NCBI Protein Accession: YP_001033956; NCBITaxon: 10390</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011165 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011165">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010804"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011165</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant fowl poxviruses (rFPVs) were constructed to express genes from serotype 1 Marek&apos;s disease virus (MDV, Gallid herpesvirus 2). rFPV/gI expressing MDV095 conferred 43% protection in maternal antibody-positive chickens when challenged with highly virulent MDV isolates [PubMed: 14562881].</rdfs:comment>
        <rdfs:label>MDV095</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 575; NCBI Gene GI: 4811454; NCBI Protein GI: 125745128; NCBI Protein Accession: YP_001034012; NCBITaxon: 10390</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011166 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011166">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010784"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011166</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Chimeric Venezuelan equine encephalitis/Sindbis virus (VEE/SIN) replicon particles were used to express the hemagglutinin (H) and fusion (F) proteins of measles virus (MV).  When challenged with wild-type MV 12 to 17 months after vaccination, all vaccinated juvenile and infant monkeys vaccinated with VEE/SIN-H, VEE/SIN-H+F, and LAV were protected from rash and viremia [PubMed: 20130066].</rdfs:comment>
        <rdfs:label>H hemagglutinin protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 577; NCBI Gene GI: 1489801; NCBI Protein GI: 9626951; NCBI Protein Accession: NP_056923; NCBITaxon: 11234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011167 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011167">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010784"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011167</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice vaccinated with a vaccinia virus recombinant encoding the fusion protein of Measles virus developed measles neutralizing antibodies.  The mice also resisted a normally lethal intracerebral inoculation of a cell-associated measles virus subacute sclerosing panencephalitis strain [PubMed: 3422488].</rdfs:comment>
        <rdfs:label>F fusion protein from Measles virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 578; NCBI Gene GI: 1489800; NCBI Protein GI: 9626950; NCBI Protein Accession: NP_056922; NCBITaxon: 11234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011168 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011168">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010784"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011168</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Lewis rats were immunized with recombinant vaccinia virus (VV) expressing various proteins of measles virus (MV). VVN (Nucleocapsid Protein) -immunized rats survived a MV challenge infection [PubMed: 1833505].</rdfs:comment>
        <rdfs:label>N nucleocapsid protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 579; NCBI Gene GI: 1489804; NCBI Protein GI: 9626946; NCBI Protein Accession: NP_056918; NCBITaxon: 11234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011169 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011169">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010784"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011169</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Lewis rats were immunized with recombinant vaccinia virus (VV) expressing various proteins of measles virus (MV). VVP (Phosphoprotein) -immunized rats were partially protected from MV challenge [PubMed: 1833505].</rdfs:comment>
        <rdfs:label>P phosphoprotein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 580; NCBI Gene GI: 1489805; NCBI Protein GI: 9626947; NCBI Protein Accession: NP_056919; NCBITaxon: 11234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011170 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011170">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010784"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011170</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Lewis rats were immunized with recombinant vaccinia virus (VV) expressing various proteins of measles virus (MV). VVM (Matrix Protein) -immunized rats were partially protected from MV challenge [PubMed: 1833505].</rdfs:comment>
        <rdfs:label>M matrix protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 581; NCBI Gene GI: 1489803; NCBI Protein GI: 9626949; NCBI Protein Accession: NP_056921; NCBITaxon: 11234</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011171 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011171">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010785"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011171</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A novel mumps vaccine with good immunity and safety was developed by selecting an antigen (HN) component of the mumps virus. The clinical and pathological observations after challenge of vaccinated rhesus monkeys indicated further that the immune response induced by this vaccine provided complete protection from wild-type virus infection [PubMed: 18597904].</rdfs:comment>
        <rdfs:label>HN</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 582; NCBI Gene GI: 1489765; NCBI Protein GI: 9695422; NCBI Protein Accession: NP_054713; NCBITaxon: 11161</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011172 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011172">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011172</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with DNA encoding Ag85B (fbpB), a candidate vaccine antigen of Mycobacterium tuberculosis, elicited in mice a low but protective CD4(+) T cell-mediated IFN-gamma response [PubMed: 20544034].</rdfs:comment>
        <rdfs:label>FbpB from M. tuberculosis</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 583; NCBI Gene GI: 885785; NCBI Protein GI: 15609023; NCBI Protein Accession: NP_216402; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011173 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011173">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011173</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Our lead construct, Mtb72F, codes for a 72-kDa polyprotein genetically linked in tandem in the linear order Mtb32(C)-Mtb39-Mtb32(N).  All forms of Mtb72F immunization tested resulted in the protection of C57BL/6 mice against aerosol challenge with a virulent strain of M. tuberculosis [PubMed: 15187142].</rdfs:comment>
        <rdfs:label>Mtb72F</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 584; NCBI Protein GI: 283801990; NCBITaxon: 32630</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011174 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011174">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011174</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protective experiments of DNA vaccine pcDNA3-MIC3 (pMIC3i) in Kumming mice showed that the vaccine could significantly prolong the survival time of the mice challenged by virulent RH strains of T. gondii [PubMed: 19800170].</rdfs:comment>
        <rdfs:label>MIC3</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 587; NCBI Gene GI: 7901253; NCBI Protein GI: 237841071; NCBI Protein Accession: XP_002369833; NCBITaxon: 508771</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011175 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011175">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011175</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>We show that the 50- to 55-kDa Apa protein, specified by the Rv1860 gene of M. tuberculosis, can elicit both lymphoproliferative response and gamma interferon (IFN-gamma) production.  A poxvirus recombinant expressing the Apa protein conferred a significant level of protective immunity in guinea pigs against a challenge dose of virulent M. tuberculosis [PubMed: 12654810].</rdfs:comment>
        <rdfs:label>Apa</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 588; NCBI Gene GI: 885896; NCBI Protein GI: 57116926; NCBI Protein Accession: YP_177849; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011176 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011176">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011176</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>MPT63 (Rv1926c), a major secreted protein of Mycobacterium tuberculosis, is immunoreactive in antibody assays in humans and animals and provides protection as a combined DNA vaccine in mice [PubMed: 19281533].</rdfs:comment>
        <rdfs:label>Mpt63</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 589; NCBI Gene GI: 885334; NCBI Protein GI: 15609063; NCBI Protein Accession: NP_216442; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011177 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011177">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010803"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011177</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The immunogenicity and protective efficacy of a recombinant subunit West Nile virus (WNV) vaccine was evaluated in rhesus macaques (Macaca mulatta). The vaccine consisted of a recombinant envelope (E) protein truncated at the C-terminal end, resulting in a polypeptide containing 80% of the N-terminal amino acids of the native WNV protein (WN-80E), mixed with an adjuvant (GPI-0100). Groups of monkeys were immunized with the WN-80E/GPI-0100 vaccine or an adjuvant-only control formulation. Animals were then challenged by inoculation of wild-type WNV, and the level of viremia in each animal was monitored daily for 10 days. The results showed that whereas all animals in the control group had detectable viremia for at least 3 days after challenge, all of the vaccinated animals were negative on all days after challenge. Thus, the WN-80E vaccine was 100% efficacious in protecting monkeys against infection with WNV [PubMed: 19641099].</rdfs:comment>
        <rdfs:label>E protein from West Nile virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 590; NCBI Protein GI: 111145461; NCBITaxon: 11082</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011178">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010819"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011178</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>An antiserum raised in chicken against the TM-1 polypeptide, which was produced by recombinant Escherichia coli cells and purified by column chromatography, inhibited growth of M.g. cells in vitro. Moreover, chickens immunized with this 29 kDa polypeptide (TM-1) were partially protected from a challenge with virulent M.g [PubMed: 8212828].</rdfs:comment>
        <rdfs:label>TM-1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 591; NCBI Protein GI: 7249262; NCBITaxon: 2096</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011179 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011179">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010803"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011179</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Starting with a previously designed eukaryotic expression vector, a recombinant plasmid (pCBWN) that expressed the WN virus prM and E proteins was constructed. A single intramuscular injection of pCBWN DNA induced protective immunity, preventing WN virus infection in mice and horses when subjected to challenge with the NY99-6480 strain of WNV [PubMed: 11287553].</rdfs:comment>
        <rdfs:label>PrM from West Nile virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 592; NCBI Gene GI: 5714902; NCBI Protein GI: 158516888; NCBI Protein Accession: YP_001527877; NCBITaxon: 11082</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011180 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011180">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011180</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Seventeen monoclonal antibodies to one of three main cell surface antigens of Neisseria meningitidis group B were tested for protective efficacy in the infant rat using as challenge seven strains of different class 2/3 protein serotypes.  Survival of the animals was regularly obtained with antibodies to the P1 protein and to LPS [PubMed: 2510417].</rdfs:comment>
        <rdfs:label>P1 from Neisseria meningitidis</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 594; NCBI Gene GI: 902192; NCBI Protein GI: 15676020; NCBI Protein Accession: NP_273150; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011181</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Sera of the challenge group immunized with CCPS-P64kR showed a three-fold higher bactericidal response than the sera of the group immunized with the plain CCPS and they were able to protect against challenge with Neisseria meningococci in the infant rat protection model [PubMed: 15039094].</rdfs:comment>
        <rdfs:label>LpdA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 596; NCBI Protein GI: 1017430; NCBITaxon: 487</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011182</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with purified Tbp2 survived a lethal challenge to a similar degree as animals immunized with the Tbp1-Tbp2 complex, demonstrating that Tbp2 played an important role in the protective activity observed with the complex, eliciting antibodies that are not only bactericidal but also inhibitory for meningococcal growth [PubMed: 7868259].</rdfs:comment>
        <rdfs:label>TBP2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 597; NCBI Protein GI: 1017433; NCBITaxon: 487</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011183 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011183">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010824"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011183</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with recombinant forms of a sporozoite surface antigen (r-p67), derived from either bacterial or insect cells, induces high levels of sporozoite neutralizing antibodies in cattle.In vivo immunization studies have shown that approximately 30% of immunized cattle are nonreactors to a needle LD70 sporozoite challenge, 40% experience a mild disease reaction from which they recover, and the remaining 30% suffer severe disease and are clinically indistinguishable from controls. Transient parasitosis and mild clinical reactions are also observed in challenge of cattle immunized by infection and treatment and such responses constitute immunity to ECF. Hence, p67 is able to routinely induce immunity at a level of about 70% [PubMed: 11193661].</rdfs:comment>
        <rdfs:label>P67</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 598; NCBI Protein GI: 4106806; NCBITaxon: 5875</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011184">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011184</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>NspA-containing outer membrane vesicles conferred protection against otherwise lethal intraperitoneal challenge of mice with N. meningitidis serogroup B, and sera raised against them mediated opsonophagocytosis of meningococcal strains expressing this antigen [PubMed: 15501782].</rdfs:comment>
        <rdfs:label>NspA from N. meningitidis</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 599; NCBI Protein GI: 5825543; NCBITaxon: 487</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011185">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011185</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A total of 11 meningococcal proteins that are necessary for establishing systemic infection were expressed as recombinant antigens and assessed for their ability to protect mice against live bacterial challenge against N. meningitidis; the lactate permease (LctP) elicited protective immunity [PubMed: 15964482].</rdfs:comment>
        <rdfs:label>LctP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 600; NCBI Protein GI: 254667969; NCBITaxon: 662598</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011186 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011186">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011186</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A total of 11 meningococcal proteins that are necessary for establishing systemic infection were expressed as recombinant antigens and assessed for their ability to protect mice against live bacterial challenge against N. meningitidis; ExbB, which is required for iron acquisition, elicited protective immunity [PubMed: 15964482].</rdfs:comment>
        <rdfs:label>ExbB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 601; NCBI Gene GI: 903370; NCBI Protein GI: 15677575; NCBI Protein Accession: NP_274732; NCBITaxon: 122586</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011187 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011187">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010825"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011187</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The trial vaccination of cattle against T. annulata using recombinant sporozoite antigens (SPAG-1 and p67) and/or merozoite antigens (TAMS 1-1 and 1-2). The aim of these trials was to try and enhance the levels of protection induced compared with previous trials. Different approaches were tried. SPAG-1 was expressed as a fusion protein with a His6 tag and then either incorporated into ISCOMs, with or without TAMS 1-1 and 1-2, or administered with RWL, a proprietary saponin-based adjuvant. Cross-protection studies were also performed by immunizing cattle with the T. parva sporozoite antigen, p67, and then challenging with a T. annulata sporozoite stabilate.All the data collected from these two trials indicate that SPAG-1 administered with RWL is better at inducing an effective immune response than SPAG-1 incorporated into ISCOMs, with or without the presence of merozoite antigens [PubMed: 9668470].</rdfs:comment>
        <rdfs:label>Spag-1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 602; NCBI Protein GI: 161885; NCBITaxon: 5874</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011188 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011188">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010825"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011188</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>To test the potential of subunit vaccines against T. annulata infection, we immunized four groups of three calves with either recombinant (re-) (Tams1-1 and Tams1-2) proteins or naked DNA encoding these antigens. All calves vaccinated with ISCOMs proved to be protected from T. annulata infection and had generated antibodies against both re-(Tams1-1 and Tams1-2) at the time of challenge [PubMed: 9364686].</rdfs:comment>
        <rdfs:label>TA17050 merozoite-piroplasm surface antigen Tams1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 603; NCBI Gene GI: 3864438; NCBI Protein GI: 84997996; NCBI Protein Accession: XP_953719; NCBITaxon: 353154</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011189 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011189">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011189</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intraperitoneal application of NcMAG1 suspended in saponin adjuvants lead to protection against disease in 50% of animals vaccinated in a C57Bl/6 mouse cerebral infection model [PubMed: 19835644].</rdfs:comment>
        <rdfs:label>NcMAG1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 604; NCBI Protein GI: 147886433; NCBITaxon: 29176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011190 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011190">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011190</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination with an RASV synthesizing full-length PsaA induced high titers of anti-PsaA antibodies in both systemic (IgG in serum) and mucosal (IgA in vaginal washes, nasal washes, and lung homogenates) sites. BALB/c (haplotype H2(d)) or C57BL/6 (haplotype H2(b)) mice vaccinated either orally or intranasally exhibited a significant reduction in colonization of nasopharyngeal tissues after intranasal challenge with S. pneumoniae strains compared to controls, although protection was not observed with all challenge strains. None of the vaccine constructs provided protection against intraperitoneal challenge with S. pneumoniae strain WU2 (serotype 3) [PubMed: 20479086].</rdfs:comment>
        <rdfs:label>PsaA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 605; NCBI Protein GI: 209867628; NCBITaxon: 1313</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011191 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011191">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011191</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A 90% protection rate was achieved following intra-nasal vaccination with recNcPDI emulsified in cholera toxin employing the C57Bl/6 mouse cerebral infection model when challenged with Neospora caninum tachyzoites [PubMed: 19835644].</rdfs:comment>
        <rdfs:label>NcPDI</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 606; NCBI Protein GI: 82568727; NCBITaxon: 29176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011192">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011192</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The protective effects a pneumolysin mutant (DeltaA146 Ply) against pneumococcal infections in mice was evaluated. Vaccinated mice were challenged with pneumococcal strain D39 at 1,500 times the LD50 (1.5 x 105 CFU) and the vaccinated mice survived significantly longer than control mice after challenge [PubMed: 20038538].</rdfs:comment>
        <rdfs:label>Ply</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 607; NCBI Gene GI: 4441611; NCBI Protein GI: 116515376; NCBI Protein Accession: YP_817150; NCBITaxon: 373153</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011193 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011193">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011193</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The protective effects of ATP-dependent caseinolytic protease (ClpP) was evaluated. Vaccinated mice were intraperitoneally and/or intranasally challenged with different pneumococcal strains. In intraperitoneal challenge models with pneumococcal strain D39 (serotype 2), clpP elicited some protection in mice [PubMed: 20038538].</rdfs:comment>
        <rdfs:label>ClpP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 608; NCBI Gene GI: 4441476; NCBI Protein GI: 116516216; NCBI Protein Accession: YP_816144; NCBITaxon: 373153</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011194">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011194</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The production of a recombinant vaccine was achieved following PCR amplification of putative lipoate protein ligase (Lpl), with subsequent cloning and expression of the genes in E. coli. The putative lipoate protein ligase (Lpl) , resulted in a reduced CFU titre and a trend towards reduced mortality in an animal sepsis model [PubMed: 18034862].</rdfs:comment>
        <rdfs:label>LplA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 609; NCBI Gene GI: 934072; NCBI Protein GI: 15903091; NCBI Protein Accession: NP_358641; NCBITaxon: 171101</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011195 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011195">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011195</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>NcSAG1 and NcSRS2, the two major immunodominant tachyzoite surface antigens of the apicomplexan parasite Neospora caninum, were investigated for their potential as vaccine candidates in mice.  Results suggest that a combined DNA/recombinant antigen-vaccine, based on NcSAG1 and NcSRS2, respectively, exhibited a highly significant protective effect against experimentally induced cerebral neosporosis in mice [PubMed: 12741509].</rdfs:comment>
        <rdfs:label>NcSRS2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 610; NCBI Protein GI: 5579384; NCBITaxon: 29176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011196 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011196">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011196</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>NcSAG1 and NcSRS2, the two major immunodominant tachyzoite surface antigens of the apicomplexan parasite Neospora caninum, were investigated for their potential as vaccine candidates in mice. Results suggest that a combined DNA/recombinant antigen-vaccine, based on NcSAG1 and NcSRS2, respectively, exhibited a highly significant protective effect against experimentally induced cerebral neosporosis in mice [PubMed: 12741509].</rdfs:comment>
        <rdfs:label>NcSAG1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 611; NCBI Protein GI: 4583447; NCBITaxon: 29176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011197 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011197">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011197</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with recombinant (r)PsrP(BR) had significantly less bacteria in their blood and improved survival versus controls following intranasal challenge [PubMed: 19627498].</rdfs:comment>
        <rdfs:label>PsrP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 613; NCBI Gene GI: 7329552; NCBI Protein GI: 221232510; NCBI Protein Accession: YP_002511663; NCBITaxon: 561276</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011198 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011198">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011198</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>This study used an immunisation/challenge model of transplacental transmission, based on the Qs mouse with an Nc-Liverpool challenge to investigate the vaccine potential of a number of formulations based on four recombinant proteins of N. caninum.  A mixture of MIC10 and p24B produced partial protection against transplacental transmission of N. caninum in this mouse model [PubMed: 18789996].

Note:  MIC10 must be used in conjunction with p24B in order to confer protection against N. caninum.</rdfs:comment>
        <rdfs:label>MIC10</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 614; NCBI Protein GI: 11141617; NCBITaxon: 29176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011199 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011199">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011199</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intraperitoneal immunization with recombinant SrtA was found to have  conferred to mice protection against S. pneumoniae intraperitoneal challenge and the passive transfer of immune serum before intraperitoneal challenge was also protective. Moreover, by using the intranasal challenge model,  significant reduction of bacteremia when mice were intraperitoneally immunized with SrtA was observed, while a moderate decrease of lung infection was achieved by intranasal immunization, even though no influence on nasopharynx colonization was seen [PubMed: 19433540].</rdfs:comment>
        <rdfs:label>SrtA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 615; NCBI Gene GI: 4442999; NCBI Protein GI: 116515518; NCBI Protein Accession: YP_816547; NCBITaxon: 373153</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011200 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011200">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011200</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study assessed the potential protectivity of NcMIC1-based vaccination against experimental N. caninum infection in mice.  Quantitative real-time PCR revealed that the infection intensity was significantly reduced in the group vaccinated with recNcMIC1 antigen.  Serological analysis showed that only recNcMIC1-immunized animals generated detectable antibody levels recognizing native NcMIC1. Thus, of all protocols applied, only recNcMIC1 vaccination appears to be suited to reduce cerebral infection in mice challenged with N. caninum tachyzoites [PubMed: 16108562].</rdfs:comment>
        <rdfs:label>NcMIC1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 616; NCBI Protein GI: 17226315; NCBITaxon: 29176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011201 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011201">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011201</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Glutamyl tRNA synthetase (GtS) has been found to be among the Streptococcus pneumoniae cell wall-derived proteins that have age-dependent immunogenicity in children. Here, GtS was cloned, expressed, and purified and then was used to immunize 7-week-old BALB/c OlaHsd mice. Thirty-nine percent of rGtS-immunized mice survived a lethal bacterial challenge, whereas no control mice survived [PubMed: 17703427].</rdfs:comment>
        <rdfs:label>GltX</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 617; NCBI Gene GI: 931970; NCBI Protein GI: 15901888; NCBI Protein Accession: NP_346492; NCBITaxon: 170187</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011202 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011202">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011202</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Separate groups of gerbils were immunized with purified recombinant proteins singly or in combinations and animals were then challenged with N. caninum.  The protective efficacy of each vaccination was determined by assessing animal survival rate.  The highest protection efficacy was observed for combined vaccination with NcSRS2 and NcDG1 (67.5% survival) compared to control (17.4% survival).  Vaccination with NcDG1 alone elicited 62.5% survival in the challenge model [PubMed: 15793355].</rdfs:comment>
        <rdfs:label>NcDG1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 618; NCBI Protein GI: 2149142; NCBITaxon: 29176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011203 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011203">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011203</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice were actively immunized with a fragment of choline binding protein A (CbpA; also known as PspC, Hic, and SpsA). CbpA was able to protect mice from intraperitoneal challenge with medium to very high doses of a highly virulent capsular type 2 pneumococcal strain, D39 [PubMed: 11553536].</rdfs:comment>
        <rdfs:label>CbpA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 619; NCBI Gene GI: 4441159; NCBI Protein GI: 116515359; NCBI Protein Accession: YP_817402; NCBITaxon: 373153</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011204 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011204">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011204</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Groups of BALB/c mice immunized with choline binding protein PspA were challenged with either D39 or WCH16. PspA elicited protection by using moderate challenge doses of S. pneumoniae [PubMed: 17088353].</rdfs:comment>
        <rdfs:label>PspA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 620; NCBI Gene GI: 4441373; NCBI Protein GI: 116515876; NCBI Protein Accession: YP_815641; NCBITaxon: 373153</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011205 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011205">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010828"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011205</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000332"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Separate groups of gerbils were immunized with purified recombinant proteins singly or in combinations and animals were then challenged with N. caninum. The protective efficacy of each vaccination was determined by assessing animal survival rate.  All experimental groups showed protective effects.  Vaccination with NcDG2 alone elicited 50% survival rate compared to a control survival rate of 17.4% [PubMed: 15793355].</rdfs:comment>
        <rdfs:label>NcDG2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 621; NCBI Protein GI: 3237325; NCBITaxon: 29176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011206 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011206">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011206</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice were immunized with recombinant 6-Phosphogluconate dehydrogenase (r6PGD) and boosted after 3 weeks. Immunized mice were challenged intranasally with a lethal dose of S. pneumoniae. Immunization of mice with r6PGD protected 60% (P &lt; 0.001) of mice for 5 days and 40% (P &lt; 0.05) of the mice for 21 days following intranasal lethal challenge [PubMed: 16634799].</rdfs:comment>
        <rdfs:label>Gnd</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 622; NCBI Gene GI: 4441177; NCBI Protein GI: 116515453; NCBI Protein Accession: YP_815856; NCBITaxon: 373153</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011207 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011207">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011207</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with recombinant PiaA were protected against systemic challenge to a degree similar to those immunized with an existing protein vaccine candidate, PdB (a genetically modified pneumolysin toxoid). Immunization with a combination of both PiuA and PiaA resulted in additive protection and was highly protective against systemic infection with S. pneumoniae [PubMed: 11598041].</rdfs:comment>
        <rdfs:label>PiaA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 623; NCBI Gene GI: 4442863; NCBI Protein GI: 116515816; NCBI Protein Accession: YP_815744; NCBITaxon: 373153</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011208 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011208">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010805"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011208</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A recombinant fowlpox virus expressing the fusion protein of Newcastle disease virus strain F48E8 protected chickens against virulent NDV challenge.  The protective rate was 96.7% [PubMed: 11191764].</rdfs:comment>
        <rdfs:label>F fusion protein from Newcastle disease virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 624; NCBI Gene GI: 912271; NCBI Protein GI: 11545723; NCBI Protein Accession: NP_071469; NCBITaxon: 11176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011209 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011209">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010805"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011209</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant baculoviruses containing the fusion (F) and hemagglutinin-neuraminidase (HN) glycoprotein gene of the viscerotropic velogenic (vv) Newcastle disease virus (NDV) isolate, Kr-005/00, and a lentogenic La Sota strain of the NDV were constructed.  A single dose of rNDHN(V) had a protective effect against mortality (p &lt;0.01) in chickens [PubMed: 18716451].</rdfs:comment>
        <rdfs:label>HN hemagglutinin-neuraminidase</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 625; NCBI Gene GI: 912270; NCBI Protein GI: 11545724; NCBI Protein Accession: NP_071470; NCBITaxon: 11176</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011210 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011210">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011210</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers constructed a new recombinant molecule of SERA5, namely SE36.  Vaccination of Squirrel monkeys with SE36 protein and aluminium hydroxyl gel (SE36/AHG) conferred protection against high parasitemia and boosted serum anti-SE36 IgG after P. falciparum parasite challenge [PubMed: 20493274].</rdfs:comment>
        <rdfs:label>SERA-5</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 626; NCBI Protein GI: 238629807; NCBITaxon: 5833</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011211 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011211">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010816"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011211</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination of mice with EAG (2-macroglobulin, albumin, and immunoglobulin G [IgG] binding protein) as a single antigen with EtxB (as an adjuvant) induced protection in mice against bacterial challenge, but was less protective than at affording protection than immunization with FNZ, SFS, EAG, and EtxB [PubMed: 15155624].</rdfs:comment>
        <rdfs:label>binding protein Eag</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 627; NCBI Gene GI: 7696154; NCBI Protein GI: 225870123; NCBI Protein Accession: YP_002746070; NCBITaxon: 553482</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011212 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011212">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000386"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011212</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000386"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers found that the cysteine-rich, carboxyl-terminal region of the MSP-1 protein from the rodent malarial parasite Plasmodium yoelii yoelii can be expressed in a native configuration as a fusion protein in Escherichia coli. This recombinant polypeptide elicits antibodies in mice which recognize the native parasite MSP-1. Most significantly, both inbred and outbred mice immunized with the fusion protein in Ribi adjuvant are partially and in some cases completely protected against challenge infection with an otherwise lethal parasite strain [PubMed: 8363656].</rdfs:comment>
        <rdfs:label>MSP1 from P. yoelii str. 17XNL</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 628; NCBI Gene GI: 3791597; NCBI Protein GI: 82596427; NCBI Protein Accession: XP_726257; NCBITaxon: 352914</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011213 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011213">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010816"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011213</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice were immunised i.n. with collagen-binding protein (CNE) and were subsequently subjected to infection with S. equi subsp. equi. A control group of mice was given only adjuvant. The CNE vaccinated group had a delayed onset of infection compared to the control group. Immunization with CNE led to significant protection from infection [PubMed: 16580099].</rdfs:comment>
        <rdfs:label>collagen binding, ancillary pilus subunit Cne</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 629; NCBI Gene GI: 7695900; NCBI Protein GI: 225870316; NCBI Protein Accession: YP_002746263; NCBITaxon: 553482</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011214 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011214">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010816"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011214</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Parts of the three recombinant proteins (FNZ (cell surface-bound fibronectin binding protein), SFS (secreted fibronectin binding protein), and EAG (alpha2-macroglobulin, albumin, and immunoglobulin G [IgG] binding protein)) were used to immunize mice, either subcutaneously or intranasally, prior to nasal challenge with S. equi subsp. equi. The adjuvant used was EtxB, a recombinant form of the B subunit of Escherichia coli heat-labile enterotoxin. It was shown that nasal colonization of S. equi subsp. equi and weight loss due to infection were significantly reduced after vaccination compared with a mock-vaccinated control group. This effect was more pronounced after intranasal vaccination than after subcutaneous vaccination; nearly complete eradication of nasal colonization was obtained after intranasal vaccination (P &lt; 0.001) [PubMed: 15155624].</rdfs:comment>
        <rdfs:label>Fnz</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 630; NCBI Gene GI: 7695217; NCBI Protein GI: 225869227; NCBI Protein Accession: YP_002745175; NCBITaxon: 40041</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011215 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011215">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010816"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011215</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Parts of the three recombinant proteins (FNZ (cell surface-bound fibronectin binding protein), SFS (secreted fibronectin binding protein), and EAG (alpha2-macroglobulin, albumin, and immunoglobulin G [IgG] binding protein)) were used to immunize mice, either subcutaneously or intranasally, prior to nasal challenge with S. equi subsp. equi. The adjuvant used was EtxB, a recombinant form of the B subunit of Escherichia coli heat-labile enterotoxin. It was shown that nasal colonization of S. equi subsp. equi and weight loss due to infection were significantly reduced after vaccination compared with a mock-vaccinated control group. This effect was more pronounced after intranasal vaccination than after subcutaneous vaccination; nearly complete eradication of nasal colonization was obtained after intranasal vaccination (P &lt; 0.001) [PubMed: 15155624].</rdfs:comment>
        <rdfs:label>Sfs</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 631; NCBI Gene GI: 7696331; NCBI Protein GI: 225869898; NCBI Protein Accession: YP_002745845; NCBITaxon: 553482</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011216 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011216">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010816"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011216</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The fibrinogen-binding protein (FgBP) reacted with serum taken from horses recovering from strangles and protected mice against lethal challenge from S. equi subsp. equi [PubMed: 9579073].</rdfs:comment>
        <rdfs:label>Fbp</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 632; NCBI Gene GI: 7697172; NCBI Protein GI: 225871286; NCBI Protein Accession: YP_002747233; NCBITaxon: 553482</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011217 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011217">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015475"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011217</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers produced a prototypic malaria vaccine based on a highly versatile self-assembling polypeptide nanoparticle (SAPN) platform that can repetitively display antigenic epitopes. Researchers used this platform to display a tandem repeat of the B cell immunodominant repeat epitope (DPPPPNPN)(2)D of the malaria parasite Plasmodium berghei circumsporozoite (CS) protein. Administered in saline, without the need for a heterologous adjuvant, the SAPN construct P4c-Mal conferred a long-lived, protective immune response to mice with a broad range of genetically distinct immune backgrounds including the H-2(b), H-2(d), and H-2(k) alleles. Mice were protected against an initial challenge of parasites up to 6 mo after the last immunization or for up to 15 mo against a second challenge after an initial challenge of parasites had successfully been cleared.  [PubMed: 19915055].</rdfs:comment>
        <rdfs:label>CS from P. berghei str. ANKA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 633; NCBI Gene GI: 3428738; NCBI Protein GI: 68076353; NCBI Protein Accession: XP_680096; NCBITaxon: 5823</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011218 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011218">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011218</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>CS from P. falciparum</obo:IAO_0000118>
        <obo:IAO_0000118>P. falciparum circumsporozoite protein</obo:IAO_0000118>
        <obo:IAO_0000119>https://www.ncbi.nlm.nih.gov/pubmed/18159254</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A P. berghei parasite line was used to expresses a heterologous circumsporozoite protein (CSP) from P. falciparum. A sterile immunity was obtained  by vaccination with the radiation-attenuated P. berghei parasite [PubMed: 18159254].</rdfs:comment>
        <rdfs:label>P. falciparum CSP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 634; NCBI Protein GI: 552191; NCBITaxon: 5833</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011219 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011219">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000385"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011219</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000385"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study showed that immunization with irradiated sporozoites (IrrSpz) of a P. berghei line whose endogenous CS was replaced by that of P. yoelii conferred sterile protection against challenge with wild type P. berghei sporozoites [PubMed: 19890387].</rdfs:comment>
        <rdfs:label>CS from P. yoelii str. 17XNL</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 635; NCBI Gene GI: 3830374; NCBI Protein GI: 83317409; NCBI Protein Accession: XP_731149; NCBITaxon: 352914</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011220 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011220">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011220</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000130"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with a recombinant yeast-expressed Plasmodium falciparum merozoite surface protein 3 (MSP3) protected Aotus nancymai monkeys against a virulent challenge infection [PubMed: 19073223].</rdfs:comment>
        <rdfs:label>MSP3</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 636; NCBI Protein GI: 113207288; NCBITaxon: 5833</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011221 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011221">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011221</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with Plasmodium yoelii merozoite surface protein (PyMSP)-8 protects mice from lethal malaria but does not prevent infection [PubMed: 18097046].</rdfs:comment>
        <rdfs:label>MSP8</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 637; NCBI Protein GI: 58197887; NCBITaxon: 5861</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011222 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011222">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010789"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011222</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intranasal or oral delivery of the chimeric rotavirus VP6 protein MBP::VP6 to mice elicited &gt;90% reductions in fecal rotavirus shedding after murine rotavirus challenge [PubMed: 17629371].</rdfs:comment>
        <rdfs:label>VP6 from Murine rotavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 638; NCBI Protein GI: 268080815; NCBITaxon: 28327</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011223 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011223">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011223</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with r-Pfen (recombinant P. falciparum enolase protein) showed protection against a challenge with the 17XL lethal strain of the mouse malarial parasite Plasmodium yoelii [PubMed: 17785475].</rdfs:comment>
        <rdfs:label>PF10_0155 enolase</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 639; NCBI Gene GI: 810313; NCBI Protein GI: 124802328; NCBI Protein Accession: XP_001347440; NCBITaxon: 36329</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011224 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011224">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015475"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000330"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011224</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000330"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with recombinant PbAMA-1 were partially protected from the challenge of P. berghei [PubMed: 17639690].</rdfs:comment>
        <rdfs:label>AMA-1 from P. berghei</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 640; NCBI Protein GI: 1438889; NCBITaxon: 5821</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011225 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011225">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015475"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011225</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice vaccinated with recombinant rMSP1 (rPbMSP1), which was generated from Plasmodium berghei, in alum mounted significant protective immunity against challenge infection (P &lt; 0.01). On day 121 after the booster, three out of ten mice immunized with rPbMSP1 in PBS survived parasite infection (P &lt; 0.05) and eight out of ten mice vaccinated with r MSP1 in alum did (P &lt; 0.01). Hence, immunization with MSP1 in alum obviously has conferred protective effects, which prevented death from P. berghei lethal infection in mice (P &lt; 0.01) [PubMed: 17568385].</rdfs:comment>
        <rdfs:label>MSP1 from P. berghei</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 641; NCBI Protein GI: 1762646; NCBITaxon: 5821</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011226 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011226">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010789"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011226</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system.   Neonates of animals immunized with virus-like particles composed of VP7 assembled on VP6 spherical particles were protected against challenge with the homotypic virus and significantly protected from a heterotypic challenge.  Unassembled VP7 protein provided partial protection against challenge [PubMed: 8382422].</rdfs:comment>
        <rdfs:label>VP7 from Bovine rotavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 642; NCBI Protein GI: 195661008; NCBITaxon: 10927</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011227 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011227">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010789"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011227</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system.  Challenge of neonates born to animals immunized with VP4 protein on assembled particles or in cell lysates showed protection against challenge with both homologous (bovine C486) and heterologous (SA-11) strains of rotavirus [PubMed: 8382422].</rdfs:comment>
        <rdfs:label>VP4 from Bovine rotavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 643; NCBI Protein GI: 172054621; NCBITaxon: 10927</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011228 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011228">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011228</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization of mice with subunit vaccines based on the Plasmodium yoelii 17kDa hepatocyte erythrocyte protein (PyHEP17), orthologue of Plasmodium falciparum exported protein 1 (PfExp1), induces antigen-specific immune responses and protects against sporozoite challenge [PubMed: 17303242].</rdfs:comment>
        <rdfs:label>HEP17</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 644; NCBI Protein GI: 1399353; NCBITaxon: 5861</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011229">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011229</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunized animals were challenged in vivo with various parasite strains or clones of malaria. Immunization with the PfEMP1-DBL1 alpha domain abolished the PfEMP1-dependent sequestration of the homologous strain in immunized rats and substantially inhibited parasite adhesion in immunized monkeys. Protection against sequestration of heterologous parasite strains was also confirmed by direct or indirect challenge in the rat model [PubMed: 17074852].</rdfs:comment>
        <rdfs:label>EMP1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 645; NCBI Protein GI: 2961468; NCBITaxon: 5833</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011230 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011230">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015473"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011230</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization of BALB/c mice and Aotus monkeys with PvMSP-1 induced IgG antibodies (titer &gt; 10(6)) that cross-reacted with P. vivax parasites. Immunized monkeys displayed partial protection against a challenge with P. vivax blood stages [PubMed: 16291762].</rdfs:comment>
        <rdfs:label>MSP1 from P. vivax</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 646; NCBI Protein GI: 26985160; NCBITaxon: 5855</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011231 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011231">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010788"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011231</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A DNA vaccine based on lysosome-targeted glycoprotein of the rabies virus was evaluated in BALB/c mice. It imparted partial protection (60%) against challenge with 20 LD(50) of the challenge virus standard (CVS) strain of rabies virus [PubMed: 19741168].</rdfs:comment>
        <rdfs:label>Glycoprotein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 647; NCBI Protein GI: 56384945; NCBITaxon: 11292</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011232">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010788"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011232</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice vaccinated intraperitoneally (i.p.) with 10^7 p.f.u. of a vaccinia virus recombinant expressing either the glycoprotein (rVac-G) or nucleoprotein (rVac-N) of rabies virus 3 weeks before challenge were protected against peripheral lethal infection [PubMed: 8207400].</rdfs:comment>
        <rdfs:label>RABVgp1 nucleoprotein N</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 648; NCBI Gene GI: 1489853; NCBI Protein GI: 9627198; NCBI Protein Accession: NP_056793; NCBITaxon: 11292</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011233 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011233">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011233</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Two large fragments of PfKbeta representing the N- and C-terminal halves were expressed in E. coli. The recombinant proteins were highly immunogenic in mice, and also found to be the target for immune response in natural infections of Plasmodium spp.  Immunization with recombinant PfKbeta fragments was partially protective against a heterologous challenge infection in mice [PubMed: 15987343].</rdfs:comment>
        <rdfs:label>Kbeta</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 649; NCBI Gene GI: 813054; NCBI Protein GI: 124506397; NCBI Protein Accession: XP_001351796; NCBITaxon: 36329</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011234">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010846"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011234</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with one of the constructs of M. vaccae expressing OmpA in combination with booster immunization with the homologous recombinant protein protected a significant portion of mice from lethal challenge [PubMed: 11738766].</rdfs:comment>
        <rdfs:label>OmpA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 650; NCBI Protein GI: 112710; NCBITaxon: 783</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011235 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011235">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010846"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011235</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>R. rickettsii OmpB contain B and T lymphocyte epitopes. Immunizations with each of two fragments from OmpB (rompB1550-2738 and rompB2459-4123) conferred protection against challenge with a lethal dose of R. conorii. Protection appeared to be better achieved among the groups that received both DNA and recombinant protein immunizations, although recombinant protein immunizations alone provided some protection [PubMed: 11693887].</rdfs:comment>
        <rdfs:label>OmpB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 651; NCBI Protein GI: 6685726; NCBITaxon: 783</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011236">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015474"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011236</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Oral immunization of mice with Escherichia coli-expressed Plasmodium yoelii merozoite surface protein 4/5 or the C-terminal 19-kDa fragment of merozoite surface protein 1 induced systemic antibody responses and protected mice against lethal malaria infection [PubMed: 15385527].</rdfs:comment>
        <rdfs:label>MSP4/5</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 652; NCBI Protein GI: 49798469; NCBITaxon: 73239</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011237 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011237">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015476"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000389"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011237</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000389"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with a refolded, recombinant, Plasmodium chabaudi AMA1 fragment (AMA1B) can withstand subsequent challenge with P. chabaudi adami [PubMed: 10861076].</rdfs:comment>
        <rdfs:label>AMA-1 from P. chabaudi</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 653; NCBI Protein GI: 1469500; NCBITaxon: 5825</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011238 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011238">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010800"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011238</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant adenovirus expressing gB (rAd-gB) was found to induce effective protective immunity against a virulent viral infection, regardless of whether it was administered via the muscular or systemic route [PubMed: 19116444].</rdfs:comment>
        <rdfs:label>GB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 654; NCBI Protein GI: 4138504; NCBITaxon: 10345</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011239 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011239">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010800"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011239</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A trial vaccine containing pseudorabies virus (PRV) glycoprotein gC as the main component showed excellent protection against virulent virus infection in pigs [PubMed: 9300361].</rdfs:comment>
        <rdfs:label>UL44 from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 655; NCBI Gene GI: 2952505; NCBI Protein GI: 51557513; NCBI Protein Accession: YP_068347; NCBITaxon: 10345</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011240 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011240">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010800"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011240</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The pseudorabies virus (PrV) DNA vaccine carrying the glycoprotein D (gD) gene delivered by E. coli was able to induce protective immune responses in mice against a lethal PrV challenge [PubMed: 11312026]. Immunization of mice with affinity-purified gD of Aujeszky&apos;s disease virus (ADV, Suid herpesvirus 1) induced a strong humoral immune response and protected mice against lethal ADV challenge [PubMed: 17601050].</rdfs:comment>
        <rdfs:label>US6 from Pseudorabies virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 656; NCBI Gene GI: 2952521; NCBI Protein GI: 51557553; NCBI Protein Accession: YP_068387; NCBITaxon: 10345</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011241">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011241</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A monkey vaccination trial using a Plasmodium falciparum protein fraction containing antigens of 90-110 kDa is reported.   Three monkeys out of five resisted a heavy challenge dose of highly virulent parasites.  Hsp90 was found in the immunoprecipitates obtained with SERP antisera. Interestingly, the response to hsp90 correlated with protection, high antibody titres being found only in the protected monkeys [PubMed: 8303938].</rdfs:comment>
        <rdfs:label>Hsp90</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 657; NCBI Protein GI: 1093612; NCBITaxon: 5833</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010800"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011242</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>To examine the response by IE180 more closely, a vaccine trial in mice with a vector DNA construct that contains the gene encoding for IE180, designated pcDNAIE180 was conducted.  Seven months after immunization with pcDNAIE180, an overall 25% of BALB/c, C3H/HeJ, and C57BL/6 mice receiving a lethal PrV challenge were protected [PubMed: 9586695].</rdfs:comment>
        <rdfs:label>IE180</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 658; NCBI Gene GI: 2952540; NCBI Protein GI: 51557548; NCBI Protein Accession: YP_068382; NCBITaxon: 10345</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011243 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011243">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010799"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011243</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>An open reading frame 2 plasmid (pORF2) and the capsid protein (Cap) of PCV2 were used as DNA and subunit vaccines, respectively. In FCM analysis, although pORF2 and Cap alone showed comparable efficacy in eliciting lymphoproliferative responses and Cap-specific CD4(+) T cells, pORF2 was superior to the Cap protein in triggering CD8(+) T cells. Following virus challenge, real-time PCR and histopathological analysis confirmed that only low viral DNA loads and mild microscopic lesions appeared in pORF2-immunized mice [PubMed: 18632956].</rdfs:comment>
        <rdfs:label>ORF2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 659; NCBI Protein GI: 78217439; NCBITaxon: 85708</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010787"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011244</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>To examine the mechanism of immunity in vivo, researchers used poliovirus receptor-transgenic mice on a BALB/c (H-2d) background.  Mice immunized with the vaccine strain were protected against a subsequent challenge with wild-type virus.  Protection was observed when mice received primed B cells in the presence of a VP4-specific Th1 clone.   Findings demonstrate that CD4+ T cells, specific for the internal poliovirus capsid protein, VP4, can provide effective help for a protective antibody response directed against surface capsid proteins [PubMed: 7699320].</rdfs:comment>
        <rdfs:label>VP4 from Poliovirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 660; NCBI Protein GI: 68532656; NCBITaxon: 12080</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011245">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010793"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011245</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Series of plasmid constructs encoding different forms of the envelope glycoprotein E of the flavivirus tick-borne encephalitis virus were constructed. These included a secreted recombinant subviral particle, a secreted carboxyl-terminally truncated soluble homodimer, a nonsecreted full-length form, and an inefficiently secreted truncated form. Mice were immunized using both i.m. injection and Gene Gun-mediated application of plasmids. The functional immune response was evaluated by determining specific neutralizing and hemagglutination-inhibiting Ab activities and by challenging the mice with a lethal dose of the virus.The plasmid construct encoding a secreted subviral particle, which carries multiple copies of the protective Ag on its surface, was superior to the other constructs in terms of extent and functionality of the Ab response as well as protection against virus challenge [PubMed: 10586074].</rdfs:comment>
        <rdfs:label>TBEVgp1 polyprotein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 661; NCBI Gene GI: 1489719; NCBI Protein GI: 9628432; NCBI Protein Accession: NP_043135; NCBITaxon: 11084</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011246 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011246">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010792"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011246</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Monoclonal antibodies to gE  neutralize VZV in vitro in a complement- dependent manner [PubMed: 9125048]. Guinea pigs immunized with recombinant varicella-zoster virus (VZV) glycoproteins E (gE) and I (gI) developed antigen-specific antibodies in the sera, vitreous, and conjunctival washes. Sera from immunized animals neutralized both cell-free and cell-associated VZV, and peripheral blood lymphocytes proliferated in vitro in response to recombinant gE and gI and to antigens from VZV-infected cells. Immunized guinea pigs were inoculated intravitreally with VZV, which induces chronic uveitis. VZV DNA was more rapidly cleared and infectious VZV was isolated less frequently from the retinas of animals immunized with gE and gI compared with that in controls receiving adjuvant alone [PubMed: 9697709].</rdfs:comment>
        <rdfs:label>ORF68</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 662; NCBI Gene GI: 1487709; NCBI Protein GI: 9625942; NCBI Protein Accession: NP_040190; NCBITaxon: 10335</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011247 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011247">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010792"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011247</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Monoclonal antibodies to gI neutralize VZV in vitro in a complement- dependent manner [PubMed: 3021804]. Guinea pigs immunized with recombinant varicella-zoster virus (VZV) glycoproteins E (gE) and I (gI) developed antigen-specific antibodies in the sera, vitreous, and conjunctival washes. Sera from immunized animals neutralized both cell-free and cell-associated VZV, and peripheral blood lymphocytes proliferated in vitro in response to recombinant gE and gI and to antigens from VZV-infected cells. Immunized guinea pigs were inoculated intravitreally with VZV, which induces chronic uveitis. VZV DNA was more rapidly cleared and infectious VZV was isolated less frequently from the retinas of animals immunized with gE and gI compared with that in controls receiving adjuvant alone [PubMed: 9697709].</rdfs:comment>
        <rdfs:label>ORF67</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 663; NCBI Gene GI: 1487689; NCBI Protein GI: 9625941; NCBI Protein Accession: NP_040189; NCBITaxon: 10335</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011248 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011248">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010800"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011248</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 was administered to pigs to determine if it would have a greater protective effect than a vector containing the gene for gp50 alone. Both NYVAC vectors protected pigs similarly from virulent pseudorabies virus challenge [PubMed: 8904669].</rdfs:comment>
        <rdfs:label>Gp50</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 664; NCBI Protein GI: 2440155; NCBITaxon: 10345</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011249 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011249">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010800"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011249</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 was administered to pigs to determine if it would have a greater protective effect than a vector containing the gene for gp50 alone. Both NYVAC vectors protected pigs similarly from virulent pseudorabies virus challenge [PubMed: 8904669].</rdfs:comment>
        <rdfs:label>GII</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 665; NCBI Protein GI: 1335775; NCBITaxon: 10345</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011250">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010800"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011250</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with either gII, gIII, gVI antigen or a mixture of them were challenged intraperitoneally with 8.5 x 10(3) plaque forming units of PRV. All the mice immunized with 1.5 and 4.5 micrograms of the mixture and 4.5 micrograms of the gIII antigen survived [PubMed: 1322712].</rdfs:comment>
        <rdfs:label>GIII</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 667; NCBI Protein GI: 334050; NCBITaxon: 10345</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011251 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011251">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010800"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011251</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination of mice with fusion proteins containing the N terminus of gI from Suid herpesvirus 1 are able to confer protection to mice against a lethal challenge of PRV [PubMed: 1693164].</rdfs:comment>
        <rdfs:label>GI</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 668; NCBI Protein GI: 255957222; NCBITaxon: 10345</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011252 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011252">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010791"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011252</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A recombinant, vP869, expressing prM and E induced high titers of neutralizing and hemagglutination inhibiting antibodies in mice and was protective against intracranial challenge with the French neurotropic strain of YFV [PubMed: 1736531].</rdfs:comment>
        <rdfs:label>E (envelope glycoprotein)</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 669; NCBI Protein GI: 262283879; NCBITaxon: 11089</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011253 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011253">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010830"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000336"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011253</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000336"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Horses were vaccinated with adjuvanted recombinant SnSAG1 (rSnSAG1)and 5 control (sham vaccinated) horses were vaccinated with adjuvant only.  The effect of vaccination with rSnSAG1 on in vivo infection by S. neurona was evaluated by challenging all the horses with S. neurona merozoites. The study showed that vaccination with rSnSAG-1 produced antibodies in horses that neutralized merozoites when tested by in vitro culture and significantly reduced clinical signs demonstrated by in vivo challenge [PubMed: 19794889].</rdfs:comment>
        <rdfs:label>SAG1 from Sarcocystis neurona</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 672; NCBI Protein GI: 295682690; NCBITaxon: 42890</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011254 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011254">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010789"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011254</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Both inbred BALB/c and outbred CD-1 mice were immunized with rotavirus VP2/6-rVLPs (2/6-VLPs) combined with CT-E29H, orally or intranasally (i.n.), and the comparative efficacy of different formulations was then determined.  Two immunizations with 2-6VLPs and CT-E29H were sufficient to protect BALB/c mice, regardless of the route of administration [PubMed: 11270595].</rdfs:comment>
        <rdfs:label>VP2 from Rotavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 673; NCBI Protein GI: 431460; NCBITaxon: 10970</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010789"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011255</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Plasmid DNA vaccines encoding for murine rotaviral proteins VP4, VP6, and VP7 were tested in adult BALB/c mice for their ability to induce immune responses and provide protection against rotavirus challenge.  Vaccines  encoding VP4 were effective in protecting mice against infection after rotavirus (100 ID50) challenge [PubMed: 9015117].</rdfs:comment>
        <rdfs:label>VP4 from Murine rotavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 675; NCBI Protein GI: 475695; NCBITaxon: 28327</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011256 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011256">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010789"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011256</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Plasmid DNA vaccines encoding for murine rotaviral proteins VP4, VP6, and VP7 were tested in adult BALB/c mice for their ability to induce immune responses and provide protection against rotavirus challenge.  Vaccines  encoding VP7 were effective in protecting mice against infection after rotavirus (100 ID50) challenge [PubMed: 9015117].</rdfs:comment>
        <rdfs:label>VP7 from Murine rotavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 676; NCBI Protein GI: 475697; NCBITaxon: 28327</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011257 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011257">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010789"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011257</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>VP6 derived from Group A rotavirus conferred in vivo partial protection against rotavirus challenge in a neonatal mouse model [PubMed: 18632867].</rdfs:comment>
        <rdfs:label>VP6 from Rotavirus A</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 677; NCBI Gene GI: 7011372; NCBI Protein GI: 210136699; NCBI Protein Accession: YP_002302229; NCBITaxon: 28875</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011258 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011258">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010789"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011258</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system.  Challenge of neonates born to animals immunized with VP6 protein showed partial protection [PubMed: 8382422].</rdfs:comment>
        <rdfs:label>VP6 from Bovine rotavirus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 678; NCBI Protein GI: 195661002; NCBITaxon: 10927</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011259 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011259">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010791"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011259</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Protection from lethal viral infection has been achieved with passively administered monoclonal antibody specific for flavivirus glycoprotein NS1 [PubMed: 1736531]. Immunization of monkeys with yellow fever virus-specified nonstructural protein NS1 resulted in protection against fatal hepatitis as well as marked reduction in the magnitude of viremia after subcutaneous challenge with yellow fever virus [PubMed: 3783816].</rdfs:comment>
        <rdfs:label>NS1 (non-structural protein 1)</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 684; NCBITaxon: 11089</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011260 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011260">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011260</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge.  A truncated portion of the LACK antigen (LACKp24) was able to induce the highest protective effect compared to other constructs.  The DNA vaccine encoding LACK was able to induce partial protection in mice [PubMed: 18951941].</rdfs:comment>
        <rdfs:label>LACK</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 734; NCBI Nucleotide GI: 1276476; NCBI Protein GI: 1276477; NCBI Protein Accession: AAA97577.1; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011261">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010767"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011261</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study compared the handling of overlapping 24-mer peptides from HIV Nef either mixed or covalently linked in tandem in one protein.  With adjuvant, overlapping peptides were capable of protecting Balb/c mice against lethal viral challenge with 3 108 plaque forming units of vv-nef, whereas the intact protein was less protective [PubMed: 19193636].</rdfs:comment>
        <rdfs:label>Nef</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 707; NCBI Gene GI: 156110; NCBI Protein GI: 28872818; NCBI Protein Accession: NP_057857; NCBITaxon: 11676</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011262 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011262">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010767"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011262</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>HIV-1 DNA plasmids expressing Env, Gag and Tat, either alone or combined with the corresponding protein immunogens formulated in the MF59 adjuvant, resulted in protection against an experimental HIV-1 infection in C57Bl/6 mice [PubMed: 17707956].</rdfs:comment>
        <rdfs:label>Tat</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 711; NCBI Gene GI: 155871; NCBI Protein GI: 9629358; NCBI Protein Accession: NP_057853; NCBITaxon: 11676</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011263 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011263">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010767"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011263</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>HIV-1 DNA plasmids expressing Env, Gag and Tat, either alone or combined with the corresponding protein immunogens formulated in the MF59 adjuvant, resulted in protection against an experimental HIV-1 infection in C57Bl/6 mice [PubMed: 17707956].</rdfs:comment>
        <rdfs:label>Gag from HIV 1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 713; NCBI Gene GI: 155030; NCBI Protein GI: 9629360; NCBI Protein Accession: NP_057850; NCBITaxon: 11676</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011264 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011264">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011264</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with Recombinant-derived nucleoprotein (rNP) from S. typhimurium expressing the cloned NP gene from A/NT/60/68 (Jones &amp; Brownlee, 1985) were protected against a lethal challenge with Influenza A/Puerto Rico/8/34 (A/PR8) virus but showed considerable morbidity before recovery [PubMed: 2172156].</rdfs:comment>
        <rdfs:label>NP from Influenza A virus (A/nt/60/1968(H3N2))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 718; NCBI Protein GI: 324704; NCBITaxon: 384505</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011265 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011265">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010774"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011265</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Since the E2 amino-terminal sequence for all VEE subtype viruses is conserved, we tested the protective capacity in mice of passively transferred mAb 1A2B-10 and found it to protect from both epizootic and enzootic VEE virus challenge. Since horses are an important natural host for VEE virus, pep1-19 was used to immunize horses and was found to be immunogenic and to elicit virus-reactive antibody [PubMed: 7543231].</rdfs:comment>
        <rdfs:label>E2 envelope protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 725; NCBI Protein GI: 25140296; NCBITaxon: 11036</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011266 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011266">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010776"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011266</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study demonstrated that a recombinant construction of heat-shock protein (hslU) with lypopolysaccharide (rcHSP-LPS) administered 24 hours before inoculation induced resistance to S. typhimurium infection. Protection formed after 3 injections of rcHSP-LPS with 10 mcg in each or single injection with 100 mcg/mouse. Forty to eighty percent of immunized mice survived after challenge while 90% of control animals died. Destruction of the HSP by boiling of the construction led to loss of protective effect [PubMed: 19621817].</rdfs:comment>
        <rdfs:label>HslU</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 726; NCBI Protein GI: 9650897; NCBITaxon: 90371</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011267 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011267">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010774"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011267</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The monoclonal antibody against E1 glycoprotein protect outbred albino mice from lethal infection caused by the virulent strain Trd of the VEE virus [PubMed: 7529989].</rdfs:comment>
        <rdfs:label>E1 glycoprotein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 727; NCBI Protein GI: 798795; NCBITaxon: 11036</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011268 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011268">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010776"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011268</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunisation of mice with DnaJ derived from Salmonella enterica subsp. enterica serovar Typhi str. CT18 was found to provide 70% protection against lethal challenge by S. Typhimurium indicating the possible use of DnaJ as vaccine candidate against typhoid [PubMed: 16887241].</rdfs:comment>
        <rdfs:label>DnaJ</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 728; NCBI Gene GI: 1246524; NCBI Protein GI: 16759006; NCBI Protein Accession: NP_454623; NCBITaxon: 220341</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011269 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011269">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010776"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011269</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The viaB (tviB) gene coding for the Vi antigen of Salmonella typhi Ty2 was subcloned into expression vector pYA248. The recombinant plasmid was termed SMM202 and transformed into Salmonella typhimurium 4072, an attenuated crp mutant.  Immunization of mice with Vi4072 afforded complete protection against fatal infection with virulent S. typhi Ty2 [PubMed: 1612747].</rdfs:comment>
        <rdfs:label>TviB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 729; NCBI Gene GI: 1067316; NCBI Protein GI: 29144603; NCBI Protein Accession: NP_807945; NCBITaxon: 209261</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011270 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011270">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010848"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011270</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The immune sera elicited by CTB DNA vaccine were functional and protective against V. cholerae O1 infection in mice [PubMed: 19443090].</rdfs:comment>
        <rdfs:label>CtxB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 731; NCBI Protein GI: 110264635; NCBITaxon: 127906</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011271 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011271">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010848"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011271</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Antibodies against TCP were able to protect baby mice against challenge with V. cholerae O1 of the classical but not of the El Tor biotype [PubMed: 7911787].</rdfs:comment>
        <rdfs:label>TcpA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 732; NCBI Protein GI: 21616882; NCBITaxon: 127906</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011272">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010848"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011272</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Antibodies generated against TcpF are protective against experimental V. cholerae infection in the infant mouse cholera model [PubMed: 16040956].</rdfs:comment>
        <rdfs:label>TcpF</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 733; NCBI Gene GI: 2614504; NCBI Protein GI: 15640854; NCBI Protein Accession: NP_230485; NCBITaxon: 243277</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011273">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011273</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge with L. major.  Mice inoculated pCMV3ISS-TSA developed significantly smaller lesions in their footpads after challenge with the parasite.  The vaccine was able to induce a partially protective effect [PubMed: 18951941].</rdfs:comment>
        <rdfs:label>TSA from Leishmania major</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 735; NCBI Nucleotide GI: 3411093; NCBI Protein GI: 3411094; NCBI Protein Accession: AAC31146.1; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011274 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011274">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011274</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge with L. major. Mice inoculated pCMV3ISS-LmSTI1 developed significantly smaller lesions in their footpads after challenge with the parasite. The vaccine was able to induce a partially protective effect [PubMed: 18951941].</rdfs:comment>
        <rdfs:label>LmSTI1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 736; NCBI Nucleotide GI: 1698879; NCBI Protein GI: 1698880; NCBI Protein Accession: AAB37318.1; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011275 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011275">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011275</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge with L. major.  Mice inoculated pCMV3ISS-CPa developed significantly smaller lesions in their footpads after challenge with the parasite.  The vaccine was able to induce a partially protective effect [PubMed: 18951941].</rdfs:comment>
        <rdfs:label>Cpa</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 737; NCBI Nucleotide GI: 71084305; NCBI Protein GI: 71084306; NCBI Protein Accession: AAZ23598.1; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011276 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011276">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011276</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The potential protection of Lmjsp (Leishmania major signal peptidase) was evaluated in three different vaccination strategies (DNA/DNA, Protein/Protein and DNA/Protein), against L. major infection. We demonstrated that vaccination with SPase through all three mentioned strategies induced a parasite specific Th1 response and conferred partial protection against parasite challenge. However, our results indicated that DNA/DNA strategy developed more effective protective responses than the other two approaches and induced 81% reduction in L. major parasite load [PubMed: 16481076].</rdfs:comment>
        <rdfs:label>SP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 738; NCBI Protein GI: 23168331; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011277 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011277">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011277</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers tested the ability of the entire H2B protein of L. major, its divergent or conserved regions to provide protection against virulent L. major challenge.  The divergent amino-terminal region of H2B is able to confer potent protection against a virulent challenge in BALB/c mice [PubMed: 16417957].</rdfs:comment>
        <rdfs:label>H2B</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 739; NCBI Protein GI: 13384083; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011278">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011278</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Cell-mediated immunity to Leishmania major (L. major) was induced by injecting BALB/c mice intradermally with plasmid DNA expressing the conserved L. major cell surface glycoprotein gp63 (gp63-pcDNA-3).  Challenge studies revealed that gp63-pcDNA-3 vaccination protected 30% of susceptible mice (21 of 70) from Leishmania infection [PubMed: 9741428].</rdfs:comment>
        <rdfs:label>Gp63</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 741; NCBI Protein GI: 259011719; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011279 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011279">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011279</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intraperitoneal vaccination of C3H/He mice with PSA-2 with Corynebacterium parvum as an adjuvant resulted in complete protection from lesion development after challenge infection with virulent L. major. Significant protection was also obtained in the genetically susceptible BALB/cH-2k and BALB/c mice [PubMed: 7591056].</rdfs:comment>
        <rdfs:label>PSA-2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 742; NCBI Protein GI: 1129058; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011280">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011280</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In a murine model of experimental cutaneous leishmaniasis, researchers investigated the protection elicited by injection of histone H1 (SW3.1) isolated from parasites by perchloric extraction, of a H1 recombinant protein produced in E. coli, and of H1 long and short synthetic peptides, against infection by L. major. Partial protection was achieved in most of the animals as shown by reduction in lesion size, upon immunization with histone H1 or its peptides, provided that the region 1-60 was present in the molecule [PubMed: 10580198].</rdfs:comment>
        <rdfs:label>SW3.1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 743; NCBI Protein GI: 4008565; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011281">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010835"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011281</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Together with poloxamer 407 as adjuvant the recombinant type I (rCPB) cysteine proteinase of Leishmania major was screened as a potential vaccines against L. major in a mouse model.  Using the footpad thickness increase to monitor the clinical outcome/cutaneous lesion at site of L. major delivery, it was possible to document that rCPB allowed BALB/c mice to mount a partial protective response [PubMed: 12057598].</rdfs:comment>
        <rdfs:label>Cpb</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 744; NCBI Protein GI: 54287314; NCBITaxon: 5664</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011282 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011282">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010836"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011282</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Upon challenge with L. infantum, C57BL/6 mice immunized with SMT formulated in MPL-SE adjuvant showed significantly lower parasite burdens in both spleens and livers compared with non-immunized mice or mice injected with adjuvant alone [PubMed: 17804125].</rdfs:comment>
        <rdfs:label>SMT</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 745; NCBI Protein GI: 146104463; NCBITaxon: 435258</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011283 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011283">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010836"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011283</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study examined the immunogenic properties of the Leishmania infantum acidic ribosomal protein P0 (LiP0) in the BALB/c mouse model.  When mice were immunized with pcDNA3-LiP0, noticeable protection against L. major infection was achieved [PubMed: 14573678].</rdfs:comment>
        <rdfs:label>LIPO-A</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 746; NCBI Protein GI: 730579; NCBITaxon: 5671</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011284 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011284">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010836"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011284</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB/c mice immunized with a DNA vector expressing p36/LACK of Leishmania infantum followed by a booster with VVp36/LACK induced significant protection against Leishmania major infection [PubMed: 11489418].</rdfs:comment>
        <rdfs:label>P36/LACK</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 747; NCBI Protein GI: 134085114; NCBITaxon: 5671</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011285 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011285">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010836"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011285</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following infection with L. infantum promastigotes, five out of eight beagle dogs immunized with H1 Montanide remained free of clinical signs, compared to two out of eight dogs in the control group.  The results demonstrate that H1 antigens with Montanide were able to induce partial protection against canine leishmaniasis, even under extreme experimental challenge conditions [PubMed: 17576026].</rdfs:comment>
        <rdfs:label>H1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 748; NCBI Nucleotide GI: 78146499; NCBI Protein GI: 78146500; NCBI Protein Accession: ABB22792.1; NCBITaxon: 5671</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011286 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011286">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010836"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011286</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following infection with L. infantum promastigotes, four out of eight beagle dogs immunized with HASPB1 Montanide remained free of clinical signs, compared to two out of eight dogs in the control group.  The results demonstrate that HASPB1 antigens with Montanide were able to induce partial protection against canine leishmaniasis, even under extreme experimental challenge conditions [PubMed: 17576026].</rdfs:comment>
        <rdfs:label>HASPB1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 749; NCBI Nucleotide GI: 3724133; NCBI Protein GI: 3724134; NCBI Protein Accession: CAA09789.1; NCBITaxon: 5661</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011287 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011287">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010798"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011287</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In 1923, it was discovered that treatment with formalin eliminated the toxicity of diphtheria toxin (DT) without destroying its immunogenicity. Formalinreated DT, now called diphtheria toxoid, rapidly became the preferred vaccine against diphtheria, and diphtheria toxoid (usually in combined vaccines, such as diphtheriaetanus toxoidsertussis vaccine [DTP] or diphtheriaetanus toxoidscellular pertussis vaccine [DTaP] for children and tetanusiphtheria toxoids vaccine for adults [Td]) is still used throughout the world for active immunization against diphtheria [PubMed: 10657208].</rdfs:comment>
        <rdfs:label>Tox</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 750; NCBI Protein GI: 38199106; NCBITaxon: 1717</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011288 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011288">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010837"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011288</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Susceptible BALB/c mice were immunized with the DNA encoding P4 alone, P4/IL-12, or P4/HSP70 prior to challenge with L. amazonensis promastigotes.  Mice immunized with P4 alone had a delayed onset of lesion development and significantly smaller lesions than the infection control group at 11 weeks postinfection (P &lt; 0.05).  P4/IL-12 immunized animals showed no sign of lesion development in three independent experiments (P &lt; 0.01).  Our results indicate that different vaccine combinations, including DNA encoding P4, HSP70, or IL-12, can provide significant protection against both Old World and New World cutaneous leishmaniasis [PubMed: 14573646].</rdfs:comment>
        <rdfs:label>P4 from Leishmania amazonensis</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 751; NCBI Nucleotide GI: 29165286; NCBI Protein GI: 29165287; NCBI Protein Accession: AAO65599.1; NCBITaxon: 5659</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011289 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011289">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011289</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>To examine the efficacy of a new mode of recombinant viral vaccine, a vaccine was constructed of two non-transmissible Sendai viruses (rSeV/dF) encoding the full-length parasite antigen amastigote surface protein-2 (ASP2) or ASP2 fused with a mono-ubiquitin on its N-terminus (UASP2). C57BL/6 mice immunized intranasally with rSeV/dF expressing either ASP2 or UASP2 showed significantly suppressed parasitemia and could be protected from lethal T. cruzi challenge [PubMed: 19712768].</rdfs:comment>
        <rdfs:label>T. cruzi amastigote surface protein-2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 752; NCBI Protein GI: 284180153; NCBITaxon: 5693</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011290 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011290">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010837"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011290</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>DNA vaccination in BALB/c mice with the LAWD (for Leishmania antigenic WD protein) and IL-12 genes significantly delayed lesion development from challenge with Leishmania amazonensis, which correlated with a dramatic reduction in parasite burdens [PubMed: 15039343].</rdfs:comment>
        <rdfs:label>WD</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 753; NCBI Nucleotide GI: 38455440; NCBI Protein GI: 38455441; NCBI Protein Accession: AAR20840.1; NCBITaxon: 5659</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011291 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011291">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010837"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011291</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization of CBA mice with the M-2 glycoprotein of L. amazonensis and C. parvum adjuvant resulted in complete protection against a challenge infection of 10^4 and 10^6 late log-phase promastigotes of L. amazonensis. In the BALB/c strain, complete protection was observed in some of the immunized animals (28 to 50%); in the rest of the mice the onset of infection was significantly delayed. Protective immunity for C57BL/6 mice was observed only at the low infecting dose (10(4) L. amazonensis organisms) [PubMed: 3182080].</rdfs:comment>
        <rdfs:label>M2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 754; NCBI Nucleotide GI: 2828562; NCBI Protein GI: 2828563; NCBI Protein Accession: AAC08302.1; NCBITaxon: 5659</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011292">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010837"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011292</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>cDNAs encoding L. m. amazonensis gp46 antigen were subcloned into the VR1012 plasmid, and susceptible BALB/c mice were immunised with two i.m. injections of 100 microg of plasmid DNA.  Mice were challenged by the injection of 4 x 10^6 L. m. mexicana parasites in the foot pad to evaluate protection. Measurement of lesion size indicated that mice immunised with VR012-GP46 were partially protected against infection [PubMed: 11713811].</rdfs:comment>
        <rdfs:label>Gp46</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 755; NCBI Nucleotide GI: 159320; NCBI Protein GI: 159321; NCBI Protein Accession: AAA29234.1; NCBITaxon: 5659</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011293 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011293">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011293</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>To study the protective effects in vivo of cruzipain-specific Th1 responses against systemic T. cruzi challenges, mice  were immunized with recombinant cruzipain plus interleukin 12 (IL-12) and a neutralizing anti-IL-4 MAb. These immunized mice developed potent cruzipain-specific memory Th1 cell responses and were significantly protected against normally lethal systemic T. cruzi challenges. To study whether cruzipain could induce mucosal immune responses relevant for vaccine development, recombinant attenuated Salmonella enterica serovar Typhimurium vaccines expressing cruzipain were prepared. BALB/c mice immunized with salmonella expressing cruzipain were significantly protected against T. cruzi mucosal infection [PubMed: 12183554].</rdfs:comment>
        <rdfs:label>T. cruzi Cruzipain</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 756; NCBI Protein GI: 1136308; NCBITaxon: 5693</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011294 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011294">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011294</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>To develop a vaccine strategy taking advantage of activated CD8(+)T cells,a DNA vaccine, designated pGFP-TSA1, encoding a fusion protein linking GFP to a single CTL epitope of TSA1(TS), a leading candidate for vaccine against T. cruzi was constructed. C57BL/6 mice vaccinated with this plasmid showed suppressed parasitemia and prolonged survival. Vaccination with pGFP-TSA1 enhanced epitope-specific cytotoxicity and IFN-gamma secretion by CD8(+)T cells [PubMed: 18321749].</rdfs:comment>
        <rdfs:label>T. cruzi TS</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 757; NCBI Protein GI: 258547365; NCBITaxon: 5693</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011295 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011295">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010837"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011295</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A 500 bp fragment encoding an isoform of cysteine proteinase (CP) from Leishmania (Leishmania) amazonensis was subcloned and expressed in the pHis vector, resulting in a recombinant protein of 24 kDa, rLacys24.  Immunization of BALB/c mice with rLacys24 plus CFA adjuvant resulted in a low but significant decrease of foot lesions after challenge with L. (L.) amazonensis compared to those exhibited by control mice [PubMed: 19735658].</rdfs:comment>
        <rdfs:label>CP cysteine proteinase</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 758; NCBI Nucleotide GI: 30142041; NCBI Protein GI: 30142042; NCBI Protein Accession: AAN34826.1; NCBITaxon: 5659</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011296 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011296">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011296</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Following the intramuscular immunization of H-2(b) and H-2(d) mice with a plasmid DNA encoding an N-terminally truncated TSA-1 lacking or containing the C-terminal nonapeptide tandem repeats, the antibody level, CTL response, and protection against challenge with T. cruzi were assessed. In H-2(b) mice, antiparasite antibodies were induced only by immunization with the DNA construct encoding TSA-1 containing the C-terminal repeats. However, both DNA constructs were efficient in eliciting long-lasting CTL responses against the protective H-2Kb-restricted TSA-1515-522 epitope. In H-2(d) mice, inoculation with either of the two TSA-1-expressing vectors effectively generated antiparasite antibodies and primed CTLs that lysed T. cruzi-infected cells in an antigen-specific, MHC class I-restricted, and CD8(+)-T-cell-dependent manner. When TSA-1 DNA-vaccinated animals were challenged with T. cruzi, 14 of 22 (64%) H-2(b) and 16 of 18 (89%) H-2(d) mice survived the infection [PubMed: 9784506].</rdfs:comment>
        <rdfs:label>T. cruzi TSA-1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 759; NCBI Protein GI: 162315; NCBITaxon: 5693</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011297 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011297">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011297</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A complement regulatory protein (CRP) of Trypanosoma cruzi was evaluated as a vaccine candidate in a murine model of experimental T. cruzi infection. Recombinant CRP derived from an Escherichia coli expression system and a plasmid encoding the full-length crp structural gene under the control of a eukaryotic promoter were used to immunize BALB/c mice. Immunization with both protein and DNA vaccines resulted in a Th1-type T-cell response, comparable antibody titers, and similar immunoglobulin G isotype profiles. Only mice immunized with the crp DNA plasmid produced antibodies capable of lysing the parasites in the presence of complement and were protected against a lethal challenge with T. cruzi trypomastigotes [PubMed: 10948115].</rdfs:comment>
        <rdfs:label>T. cruzi CRP-10</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 760; NCBI Protein GI: 1389837; NCBITaxon: 5693</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011298 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011298">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011298</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The vaccine efficacy of a  putative candidate antigen against T. cruzi infection and disease in a mouse model. C57BL/6 mice vaccinated with a T. cruzi G4-encoding plasmid and cytokine (interleukin-12 and granulocyte-macrophage colony-stimulating factor) expression plasmids elicited a strong Th1-type antibody response dominated by immunoglobulin G2b (IgG2b)/IgG1 isotypes. The dominant IgG2b/IgG1 antibody response was maintained after a challenge infection and was associated with 90% control of the acute-phase tissue parasite burden and an almost undetectable level of tissue parasites during the chronic phase, as determined by a sensitive T. cruzi 18S rRNA gene-specific real-time PCR approach [PubMed: 18550728].</rdfs:comment>
        <rdfs:label>T. cruzi G4</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 761; NCBI Protein GI: 52424038; NCBITaxon: 5693</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011299 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011299">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011299</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The vaccine efficacy of a putative candidate antigen against T. cruzi infection and disease in a mouse model. C57BL/6 mice vaccinated with a T. cruzi G2-encoding plasmid and cytokine (interleukin-12 and granulocyte-macrophage colony-stimulating factor) expression plasmids elicited a strong Th1-type antibody response dominated by immunoglobulin G2b (IgG2b)/IgG1 isotypes. The dominant IgG2b/IgG1 antibody response was maintained after a challenge infection and was associated with 50% control of the acute-phase tissue parasite burden and an almost undetectable level of tissue parasites during the chronic phase, as determined by a sensitive T. cruzi 18S rRNA gene-specific real-time PCR approach [PubMed: 18550728].</rdfs:comment>
        <rdfs:label>T. cruzi G2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 762; NCBI Protein GI: 205278890; NCBITaxon: 5693</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011300 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011300">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011300</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Tc00.1047053434931.10</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>C57BL/6 mice were immunized s.c. with recombinant PFR-2 (PAR2)  protein co-adsorbed to alum with rIL-12. rPFR-2 immunized animals were able to successfully resolve parasitemia by day 30 p.i., with the peak parasitemia occurring between days 17 and 21 p.i. [PubMed: 12798650].</rdfs:comment>
        <rdfs:label>T. cruzi PAR2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 763; NCBI Gene GI: 3532027; NCBI Protein GI: 71398801; NCBI Protein Accession: XP_802646; NCBITaxon: 353153</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011301 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011301">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010838"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011301</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000164"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>C57BL/6 mice were immunized s.c. with recombinant PFR-1 (PAR1) protein co-adsorbed to alum with rIL-12. rPFR-1 immunized animals were able to successfully resolve parasitemia by day 30 p.i., with the peak parasitemia occurring between days 17 and 21 p.i. [PubMed: 12798650].</rdfs:comment>
        <rdfs:label>T. cruzi PAR1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 764; NCBI Protein GI: 2209137; NCBITaxon: 5693</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011302 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011302">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010782"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011302</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Skin and mucosal vaccination of ponies with HA from influenza virus A/equine/Ky/1/81 provided complete protection from clinical signs of infection after challenge, while skin vaccination provided partial protection; DNA vaccination provided partial protection from viral shedding [PubMed: 10403592].</rdfs:comment>
        <rdfs:label>HA from Influenza A virus (A/equine/Kentucky/1/1981(H3N8))</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 765; NCBI Nucleotide GI: 166079523; NCBI Protein GI: 166079524; NCBI Protein Accession: ABY81481.1; NCBITaxon: 475467</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011303 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011303">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010840"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011303</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Flagellin encoding plasmid DNA was injected into Balb/c mice intramuscularly and this elicited both a humoral and a cellular immune response. Subsequent intravenous challenge of the vaccinated Balb/c mice with 10^5CFU of B. pseudomallei resulted in the number of bacterial cells detected in liver and/or spleen being significantly reduced in the flagellin plasmid DNA vaccinated mice. At 7 days subsequent to infection of B. pseudomallei, 5/6 (83%) of flagellin plasmid DNA vaccinated mice had survived [PubMed: 16169637].</rdfs:comment>
        <rdfs:label>FliC</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 770; NCBI Protein GI: 1929918; NCBITaxon: 28450</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011304 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011304">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010839"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011304</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Transgenic rice immunization expressing the Chlamydophila psittaci (Cp. psittaci) antigen (MOMP) fused to the B subunit of Escherichia coli heat-labile enterotoxin (LTB) induced partial protection (53.3%) against a lethal challenge with the highly virulent Cp. psittaci 6BC strain in a BALB/c mouse model [PubMed: 19146896].</rdfs:comment>
        <rdfs:label>MOMP from C. psittaci 6BC</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 771; NCBI Nucleotide GI: 40568; NCBI Protein GI: 40569; NCBI Protein Accession: CAA40300.1; NCBITaxon: 331636</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011305 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011305">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010841"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011305</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>This report describes the successful cloning of the E2 gene of WEEV and expression in Escherichia coli as inclusion bodies.  The immunogenicity of the refolded rE2 protein was demonstrated by strong humoral and cell mediated immune (CMI) responses in rE2-immunized BALB/c mice. The current study also demonstrated that rE2-immunized mice could be partially protected from lethal challenge of WEEV [PubMed: 17499379].</rdfs:comment>
        <rdfs:label>E2 from Western equine encephalomyelitis virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 773; NCBI Protein GI: 29611992; NCBITaxon: 11039</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011306 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011306">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010841"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011306</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain [PubMed: 19923571].

Note:  The E1 glycoprotein is part of the 6K-E1 structural protein</rdfs:comment>
        <rdfs:label>E1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 774; NCBI Nucleotide GI: 17148716; NCBI Protein GI: 17148717; NCBI Protein Accession: AAL35792.1; NCBITaxon: 11039</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011307 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011307">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010841"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011307</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain [PubMed: 19923571].

Note:  The 6K protein is part of the 6K-E1 structural protein</rdfs:comment>
        <rdfs:label>6K</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 775; NCBI Protein GI: 29611993; NCBITaxon: 11039</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011308 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011308">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010842"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011308</metadata:prefixIRI>
        <obo:IAO_0000115>A Cp23 protein that is part of Crptosporidium parvum</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In this study, Cp23 antigen was investigated as a vaccine candidate using the DNA vaccine model in adult interleukin-12 (IL-12) knockout (KO) mice, which are susceptible to C. parvum infection.  Cp23-DNA vaccination induced a 50-60% reduction in oocysts shedding, indicating a partial protection against C. parvum infection in IL-12 KO mice [PubMed: 17487508].</rdfs:comment>
        <rdfs:label>Cp23 from Crptosporidium parvum</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 776; NCBI Protein GI: 88659549; NCBITaxon: 5807</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011309 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011309">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010842"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011309</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Preparturient cows were immunized three times over a six-week period with recombinant plasmid DNA encoding the Cryptosporidium parvum CP15/60 antigen by injecting the DNA in the mammary gland.  Colostrum from these cows contained Ab specific for C. parvum sporozoites and oocysts as indicated by immunofluorescence Ab (IFA) staining.  Mice receiving immune colostrum showed partial protection (about 50% reduction) against intestinal C. parvum development compared to mice receiving control colostrum. This protection was evident at a challenge dose of 10^3 C. parvum oocysts per mouse [PubMed: 10392628].</rdfs:comment>
        <rdfs:label>CP15/60</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 777; NCBI Nucleotide GI: 170676501; NCBI Protein GI: 170676502; NCBI Protein Accession: ACB30404.1; NCBITaxon: 5807</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011310">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010843"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011310</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A subunit vaccine formulation containing only recombinant, soluble, attachment glycoprotein G from HeV (sG(HeV)) and CpG adjuvant was evaluated as a potential NiV vaccine in the cat model.  Upon oronasal challenge with NiV (50,000TCID50), all vaccinated cats were protected from disease although virus was detected on day 21 post-challenge in one animal [PubMed: 18556094].</rdfs:comment>
        <rdfs:label>G glycoprotein from Hendra virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 779; NCBI Gene GI: 1446471; NCBI Protein GI: 29468607; NCBI Protein Accession: NP_047112; NCBITaxon: 63330</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011311 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011311">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010844"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011311</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A recombinant baculovirus encoding a dengue (DEN)-2 virus envelope glycoprotein truncated of 102 amino acids (aa) at its C-terminus (D2EA102) was constructed. Both intracellular and extracellular D2EA102 induced neutralizing antibodies in mice and were thus immunogenic. Sixty eight percent (P &lt; 0.001) of mice vaccinated with 5 gg of extracellular D2EA102 protein were protected against lethal challenge [PubMed: 7826210].</rdfs:comment>
        <rdfs:label>E protein from Dengue virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 780; NCBI Protein GI: 202078796; NCBITaxon: 11060</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011312 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011312">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010844"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011312</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The protective efficacy and immune responses of mice intramuscularly injected with plasmid encoding DEN-2 non-structural protein 1 (NS1) was evaluated. Intravenously challenged by lethal DEN-2, mice vaccinated with NS1-DNA exhibited a delay onset of paralysis, a marked decrease of morbidity, and a significant enhancement of survival [PubMed: 12922127].</rdfs:comment>
        <rdfs:label>NS1 from Dengue virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 781; NCBI Protein GI: 288848; NCBITaxon: 11060</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011313 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011313">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010845"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011313</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Hamsters were immunized subcutaneously with either 107 PFU of VV-NiV.G or VV-NiV.F expressing the G and F glycoproteins, respectively, or with the two combined.  When the VV-NiV.G-vaccinated animals were challenged with Nipah virus 3 months after the last immunization (1,000 PFU/animal intraperitoneally), there was complete protection against mortality [PubMed: 14694115].</rdfs:comment>
        <rdfs:label>G glycoprotein from Nipah virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 782; NCBI Gene GI: 920955; NCBI Protein GI: 13559814; NCBI Protein Accession: NP_112027; NCBITaxon: 121791</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011314 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011314">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010845"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011314</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Hamsters were immunized subcutaneously with either 10^7 PFU of VV-NiV.G or VV-NiV.F expressing the G and F glycoproteins, respectively, or with the two combined.  When the VV-NiV.F-vaccinated animals were challenged with Nipah virus 3 months after the last immunization (1,000 PFU/animal intraperitoneally), there was complete protection against mortality [PubMed: 14694115].</rdfs:comment>
        <rdfs:label>F fusion protein from Nipah virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 783; NCBI Nucleotide GI: 8164021; NCBI Protein GI: 8164022; NCBI Protein Accession: AAF73956.1; NCBITaxon: 121791</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011315 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011315">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010844"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011315</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A recombinant vaccinia virus that expressed the pre-M protein of Dengue 4 virus was constructed. Mice immunized with the recombinant virus were protected against subsequent dengue 4 encephalitis challenge [PubMed: 1926792].</rdfs:comment>
        <rdfs:label>PrM from Dengue Virus</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 784; NCBI Protein GI: 18308086; NCBITaxon: 11070</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011316 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011316">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010844"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011316</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A recombinant vaccinia virus that expressed the M protein of Dengue 4 virus was constructed. Mice immunized with the recombinant virus were protected against subsequent dengue 4 encephalitis challenge [PubMed: 1926792].</rdfs:comment>
        <rdfs:label>M protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 785; NCBI Protein GI: 73671170; NCBITaxon: 11070</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011317 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011317">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010846"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011317</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Guinea pigs immunized with different doses of the SPA appear to be protected against challenge with live organisms as compared with nonimmunized controls [PubMed: 2122457].</rdfs:comment>
        <rdfs:label>SpaP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 786; NCBI Protein GI: 152498; NCBITaxon: 782</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011318 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011318">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010849"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011318</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The glycoprotein (GP) and nucleocapsid (NC) genes of Rift Valley fever virus (RVFV) were expressed in different expression systems and were evaluated for their ability to protect mice from virulent challenge using a prime-boost regime.  Mice vaccinated with a lumpy skin disease virus-vectored recombinant vaccine (rLSDV-RVFV) expressing the two RVFV glycoproteins (G1 and G2, expressed by the RVFV M Segment) developed neutralising antibodies and were fully protected when challenged, as were those vaccinated with a crude extract of truncated G2 glycoprotein (tG2) [PubMed: 16870311].</rdfs:comment>
        <rdfs:label>RVFVsMgp1 M protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 787; NCBI Gene GI: 956559; NCBI Protein GI: 27881464; NCBI Protein Accession: NP_777376; NCBITaxon: 11588</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010849"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011319</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunisation of mice with cDNA encoding the nucleocapsid protein induced strong humoral and lymphocyte proliferative immune responses.  Even though complete protection was not achieved by genetic immunisation, four out of eight mice vaccinated with cDNA encoding the nucleocapsid protein displayed no clinical signs of infection after challenge. In contrast, all fourteen control animals displayed clinical manifestations of Rift Valley Fever after challenge [PubMed: 19149901].</rdfs:comment>
        <rdfs:label>RVFVsSgp2 N protein</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 788; NCBI Gene GI: 956562; NCBI Protein GI: 9632367; NCBI Protein Accession: NP_049344; NCBITaxon: 11588</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011320">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010850"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011320</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The receptor-binding domain (RBD) of SARS-CoV spike (S) protein is an important target in developing safe and effective SARS vaccines. A previous study has demonstrated that vaccination with adeno-associated virus encoding RBD (RBD-rAAV) induces high titer of neutralizing antibodies. The immune responses and protective effect of the immunization with RBD-rAAV prime/RBD-specific T cell peptide boost were assessed. Compared with the RBD-rAAV prime/boost vaccination, RBD-rAAV prime/RBD-peptide (RBD-Pep) boost induced similar levels of Th1 and neutralizing antibody responses that protected the vaccinated mice from subsequent SARS-CoV challenge, but stronger Th2 and CTL responses. No significant immune responses and protective effects were detected in mice vaccinated with RBD-Pep or blank AAV alone [PubMed: 18289745].</rdfs:comment>
        <rdfs:label>S protein of SARS-CoV</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 789; NCBI Gene GI: 1489668; NCBI Protein GI: 29836496; NCBI Protein Accession: NP_828851; NCBITaxon: 694009</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011321 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011321">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010851"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011321</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice actively immunized using a recombinant V antigen (rVagHis, encoded by lcrV gene) of Y. enterocolitica were completely protected against challenge with both, Y. enterocolitica 0:8 and Y. pseudotuberculosis serotype III [PubMed: 10089162].</rdfs:comment>
        <rdfs:label>LcrV</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 790; NCBI Gene GI: 1449458; NCBI Protein GI: 32470278; NCBI Protein Accession: NP_863514; NCBITaxon: 630</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011322 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011322">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011322</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>80% of C3H/HeJ mice immunized with Eh29 administered in combination with a subclinical dose of whole cholera toxin, but not as an Eh29-CTxB fusion, showed no evidence of infection in tissue sections harvested following intracecal challenge with virulent E. histolytica trophozoites. These results suggest that Eh29 is capable of inducing protective anti-amoebic immune responses in mice following oral immunization and could be used in the development of oral vaccines against amoebiasis [PubMed: 20303954].</rdfs:comment>
        <rdfs:label>GEh29</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 791; NCBI Nucleotide GI: 399673; NCBI Protein GI: 399674; NCBI Protein Accession: CAA50324.1; NCBITaxon: 5759</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011323 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011323">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011323</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Study tested if vaccination with the E. histolytica Gal/GalNAc lectin could prevent cecal infection in a C3H mouse model of amebic colitis. Vaccination prevented intestinal infection with efficacies of 84 and 100% in the two native lectin trials and 91 and 34% in the two LecA trials.  Results show for the first time that immunization with the Gal/GalNAc lectin can prevent intestinal amebiasis in mice [PubMed: 14741152].</rdfs:comment>
        <rdfs:label>Gal/GalNAc lectin</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 792; NCBI Gene GI: 3404842; NCBI Protein GI: 67469085; NCBI Protein Accession: XP_650534; NCBITaxon: 294381</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011324 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011324">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011324</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Report describes a recombinant fusion protein containing the serine-rich Entamoeba histolytica protein (SREHP), a protective antigen derived from virulent amebae, and a bacterially derived maltose-binding protein (MBP) from an attenuated strain of Salmonella typhimurium.  Gerbils vaccinated with S typhimurium SREHP-MBP were protected against amebic liver abscess after challenge with E. histolytica, the most common extraintestinal complication of amebiasis [PubMed: 8613356].</rdfs:comment>
        <rdfs:label>SREHP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 793; NCBI Gene GI: 3402462; NCBI Protein GI: 67463194; NCBI Protein Accession: XP_648254; NCBITaxon: 294381</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011325 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011325">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011325</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Groups of C57BL/6 mice (20 per group) vaccinated with rPep1 (1 mug per dose) plus adjuvant and challenged with an intranasal inoculum began to die at about 14 to 16 days but then showed significantly greater survival than the control mice [PubMed: 16369008].</rdfs:comment>
        <rdfs:label>PEP1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 794; NCBI Protein GI: 73915320; NCBITaxon: 199306</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011326 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011326">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010852"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011326</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researcherse tested the ability of the galactose-specific adherence lectin of E. histolytica to elicit a protective immune response in conjunction with Freund&apos;s incomplete and complete adjuvants.  Four independent trials demonstrated complete protection from amebic liver abscess formation in 67% of lectin-immunized gerbils.  The gerbil antilectin antibodies were shown by Western immunoblotting to be directed to the heavy subunit (CEL-170/4) but not the light subunit of the lectin [PubMed: 1987067].</rdfs:comment>
        <rdfs:label>CEL-170/4</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 795; NCBI Protein GI: 401088; NCBITaxon: 5759</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011327 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011327">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011327</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>C57BL/6 mice immunized with rPlb showed a significant reduction of the fungal burden in their lungs at 90 days postchallenge compared to the control mice at 15 days [PubMed: 16369008].</rdfs:comment>
        <rdfs:label>PLB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 796; NCBI Protein GI: 74486661; NCBITaxon: 199306</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011328 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011328">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011328</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>C57BL/6 mice immunized with rAMN1 showed a significant reduction of the fungal burden in their lungs at 90 days postchallenge compared to the control mice at 15 days [PubMed: 16369008].</rdfs:comment>
        <rdfs:label>AMN1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 797; NCBI Protein GI: 76786276; NCBITaxon: 199306</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011329 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011329">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011329</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>ELI-Antigen 1 (ELI-Ag1) was tested for its protective capacity in BALB/c mice against intraperitoneal challenge with 2500 arthroconidia of this dimorphic fungus and was found to be highly protective [PubMed: 14505918].</rdfs:comment>
        <rdfs:label>ELI-Ag1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 798; NCBI Protein GI: 37779128; NCBITaxon: 5501</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011330 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011330">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011330</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The GEL1 mRNA of C. posadasii was detected at the highest level during the endosporulation stage of the parasitic cycle, and the mature protein was immunolocalized to the surface of endospores. BALB/c or C57BL/6 mice were immunized subcutaneously with the bacterium-expressed recombinant protein (rGel1p) to evaluate its protective efficacy against a lethal challenge of C. posadasii by either the intraperitoneal or intranasal route. In both cases, rGel1p-immune mice infected with the pathogen showed a significant reduction in fungal burden and increased survival compared to nonimmune mice [PubMed: 12761077].</rdfs:comment>
        <rdfs:label>GEL1.00</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 799; NCBI Protein GI: 14582416; NCBITaxon: 199306</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011331 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011331">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011331</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant urease (rURE) of C. immitis was expressed in Escherichia coli and tested asa vaccine candidate in BALB/c mice. BALB/c mice immunized subcutaneously with rURE and subsequently challenged by the intraperitoneal (i.p.) route with a lethal inoculum of C. immitis arthroconidia demonstrated a significant reduction in the level of C. immitis infection compared to control animals [PubMed: 11292702].</rdfs:comment>
        <rdfs:label>URE</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 800; NCBI Protein GI: 73808050; NCBITaxon: 5501</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011332</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant Pmp1 was reactive with serum from individuals with both acute and protracted disease, and evoked protection in two murine models of infection with C. posadasii [PubMed: 16495561].</rdfs:comment>
        <rdfs:label>Pmp1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 801; NCBI Protein GI: 78364922; NCBITaxon: 199306</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011333 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011333">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011333</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>C57BL6 mice were immunized with syngeneic, bone marrow-derived DCs (JAWS II cells) transfected with a cDNA encoding the protective Coccidioides-Ag2/proline-rich Ag (pra). The immunized mice were lethally challenged with C. posadasii through either an i.p. or intranasal route. Upon necropsy after 10 days of infection, fungal burden in lung and spleen of immunized mice was significantly reduced as compared with the control animals. The lung tissue homogenates of immunized animals showed higher levels of IFN-gamma. Histologically, lung tissues of immunized mice were in better condition than the control mice [PubMed: 16148136].</rdfs:comment>
        <rdfs:label>Pra</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 802; NCBI Protein GI: 42742528; NCBITaxon: 5501</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011334">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010854"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000182"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011334</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000182"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The microtubule-associate protein (MAP p15) was tested as a vaccine in mice, and tests showed that p15 (native or recombinant) generated up to 100% protection from an otherwise lethal challenge of a heterologous strain of Trypanosoma brucei [PubMed: 15161078].</rdfs:comment>
        <rdfs:label>MAPP15</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 803; NCBI Protein GI: 777767; NCBITaxon: 5691</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011335 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011335">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010855"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011335</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination with poliovirus vector containing the gene for the B subunit of H. pylori urease provides significant prophylactic and strong therapeutic protection against H. pylori in mice [PubMed: 15603891].</rdfs:comment>
        <rdfs:label>UreB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 804; NCBI Protein GI: 40737733; NCBITaxon: 210</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011336 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011336">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010855"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011336</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Researchers  prepared an oral liposome-encapsulated recombinant Helicobacter pylori (Hp) heat shock protein 60 (Hsp60) vaccine and investigate its effect against Hp infection in mice.  rHsp60 plus CT (choleratoxin), liposome-encapsulated rHsp60 and liposome-encapsulated rHsp60 plus CT had protective rates against Hp infection of 73.3%, 66.7% and 86.7%, respectively [PubMed: 15897126].</rdfs:comment>
        <rdfs:label>Hsp60</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 805; NCBI Protein GI: 397869; NCBITaxon: 210</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011337 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011337">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010855"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011337</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A study shows that vaccination of mice with HP-NAP (H. pylori NAP) induces protection against H. pylori challenge, and that the majority of infected patients produce antibodies specific for HP-NAP, suggesting an important role of this factor in immunity [PubMed: 10790422].</rdfs:comment>
        <rdfs:label>NAP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 806; NCBI Protein GI: 8777456; NCBITaxon: 210</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011338 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011338">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010854"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000182"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011338</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000182"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>BALB-c mice immunized intramuscularly with a single dose (100 microg) of a plasmid DNA encoding the 5&apos;-terminal region of the trans-sialidase (nTSA) gene of T. brucei brucei are able to produce IgG antibodies that bind to the bloodstream form of T. brucei-protein extract and recognize the recombinant nTSA protein, expressed in Escherichia coli. Furthermore, this DNA vaccination process was able to protect 60% of mice submitted to a challenge assay with the infective form of T. brucei brucei parasites [PubMed: 19582478].</rdfs:comment>
        <rdfs:label>TSA from Trypanosoma brucei</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 807; NCBI Protein GI: 62175539; NCBITaxon: 5691</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011339 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011339">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010855"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011339</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant H. pylori catalase plus CT was used for immunization, and groups of mice were challenged with the Sydney strain of H. pylori. Immunization with recombinant catalase protected a significant proportion (9 of 10) of the mice from H. pylori challenge, indicating that this enzyme should be considered as a candidate for a future vaccine [PubMed: 9353048].</rdfs:comment>
        <rdfs:label>Catalase</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 808; NCBI Protein GI: 3128145; NCBITaxon: 210</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011340 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011340">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010826"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011340</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000338"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A study  to examine the immunostimulatory properties of Leishmania infantum Hsp83 (83) to elicit humoral and cellular response against the Toxoplasma gondii Rop2 protein in an adjuvant-free vaccination system was conducted. Mice immunized with fusion Rop2-83 elicited a stronger humoral and cellular response in comparison to mice immunized with Rop2 alone, or a mix of LiHsp83 and Rop2. The fusion protein induced a Th1 type response, with predominance of specific IgG2a/IgG2c isotype and IFN-gamma secretions, whereas Rop2 alone or mixed with LiHsp83 produced a Th1/Th2 mixed response. Vaccination with fusion protein conferred a remarkable resistance against oral infection with ME49 cysts in C57BL/6 and C3H mice, in comparison to mice immunized with Rop2 alone or the protein mixture. Following lethal challenge, a significant survival rate was observed in Rop2-83 immunized Balb/c and C57BL/6 mice in comparison to control groups [PubMed: 16545504].</rdfs:comment>
        <rdfs:label>Rop2</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 809; NCBI Protein GI: 115299638; NCBITaxon: 5811</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011341 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011341">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010855"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011341</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Treatment of the Helicobacter pylori vacuolating cytotoxin with very low concentrations of formaldehyde resulted in abrogation of toxic activity in both a HeLa cell vacuolation assay and an in vivo assay of gastric epithelial damage. Detoxification had only a minimal effect on the integrity of the oligomeric or monomeric structure. The toxoid retained the ability to bind to target cells and to induce high-titer neutralizing antibodies after immunization of rabbits. Furthermore, oral immunization of mice with the toxoid resulted in protection against infective challenge with mouse-adapted strains of H. pylori [PubMed: 9353041].</rdfs:comment>
        <rdfs:label>VacA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 810; NCBI Protein GI: 50313203; NCBITaxon: 210</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011342 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011342">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010853"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011342</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The immunogenicity of a 48-kDa T-cell-reactive protein (TCRP) was investigated. Immunization of BALB/c and C3H/HeN mice with the rTCRP affords a modest but significant level of protection against an intraperitoneal challenge with C. immitis. It is suggested that the rTCRP may be able to contribute to a multicomponent vaccine designed to stimulate CMI response against the parasitic cycle of C. immitis.</rdfs:comment>
        <rdfs:label>TcrP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 811; NCBI Protein GI: 13508695; NCBITaxon: 5501</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011343 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011343">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011343</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Some of the S. sciureus monkeys immunized with MSP-3(212-380)-AS02 or GLURP(27-500)-alum were able to fully or partially control parasitaemia upon an experimental P. falciparum [Falciparum Uganda Palo Alto (FUP-SP) strain] blood-stage infection, and this protection was related to the prechallenge antibody titres induced. The data are indicative that MSP-3 and GLURP can induce protective immunity against an experimental P. falciparum infection using adjuvants that are acceptable for human use and this should trigger further studies with those new antigens [PubMed: 15049780].</rdfs:comment>
        <rdfs:label>GLURP</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 812; NCBI Gene GI: 810501; NCBI Protein GI: 124802897; NCBI Protein Accession: XP_001347628; NCBITaxon: 36329</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011344 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011344">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010815"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011344</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Asian seabass vaccinated with the OMP38 (OmpU) DNA vaccine was challenged with pathogenic V. anguillarum by intramuscular injection. A relative percent survival (RPS) rate of 55.6% was recorded [PubMed: 17337208].</rdfs:comment>
        <rdfs:label>OmpU</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 813; NCBI Protein GI: 26513901; NCBITaxon: 55601</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011345 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011345">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000665"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011146"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011345</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1067</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011146"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001818>1067</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus DNA vaccine encoding PrM</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011346 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011346">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011346</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>DeltaFTT0918</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=439</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001818>439</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>DeltaFTT0918 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011347 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011347">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011347</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/643"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000431"/>
        <rdfs:label>obsolete rLm/iglC</rdfs:label>
        <rdfs:seeAlso>VIOLIN Vaccine ID: 440</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011348 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011348">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011348</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>5CVMB</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=438</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001818>438</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>5CVMB vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011349 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011349">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012158"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011290"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5659"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011349</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L. amazonensis DNA vaccine encoding WD protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1041</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011290"/>
        <obo:VO_0001818>1041</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5659"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania amazonensis DNA vaccine encoding WD protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011350 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011350">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012159"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011285"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011350</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L. infantum H1 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1042</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011285"/>
        <obo:VO_0001818>1042</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania infantum H2 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011351 -->

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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011286"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011351</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L. infantum HASPB1 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1043</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011286"/>
        <obo:VO_0001818>1043</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania infantum HASPB2 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011352 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011352</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1036</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011149"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001818>1036</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus DNA vaccine pUJENS5</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011353 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011353">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011353</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1037</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011146"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001818>1037</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus DNA vaccine encoding E protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011354 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011354">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012158"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5659"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011354</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L. amazonensis DNA vaccine encoding GP46</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1038</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011292"/>
        <obo:VO_0001818>1038</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5659"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania amazonensis DNA vaccine encoding GP47</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011355 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011355">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012158"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5659"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011355</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L. amazonensis M2 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1039</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>1039</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5659"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania amazonensis M3 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011356 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011356">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011019"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011356</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>A. pleuropneumoniae ApxIA protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=782</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011019"/>
        <obo:VO_0001818>782</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Actinobacillus pleuropneumoniae ApxIA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011357 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011357">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011357</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pertussis Cpn60 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=797</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>797</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis Cpn60 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011359">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011359</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pertussis CyaA protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=799</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>799</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis CyaA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011360 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000763"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011360</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>V. cholerae CTB DNA Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=800</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011270"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1498"/>
        <obo:VO_0001818>800</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_666"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vibrio cholerae CTB DNA vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011361 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011361">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011039"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011361</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pertussis PTx protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=801</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011039"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>801</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis PTx protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011362 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011362">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012160"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011362</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. parvum DNA vaccine encoding CP23</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1050</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001818>1050</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5807"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Cryptosporidium. parvum DNA vaccine encoding CP24</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011363 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011363">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011363</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:C7828795</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1051</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/343</obo:IAO_0000233>
        <obo:OGG_0000000006>2064</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1612"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>1051</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: ERBB2</rdfs:comment>
        <rdfs:label>Cancer Her-2/neu Protein Subunit Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011364 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011364">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011364</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:17266027</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1052</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/315</obo:IAO_0000233>
        <obo:OGG_0000000006>6528</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>1052</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: SLC5A5</rdfs:comment>
        <rdfs:label>cancer DNA vaccine MIDGE/hNIS encoding hNIS protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011365 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011365">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011365</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:19526360</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1053</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/318</obo:IAO_0000233>
        <obo:OGG_0000000006>2315863</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>1053</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Survivin</rdfs:comment>
        <rdfs:label>cancer DNA vaccine pSURV encoding Survivin</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011366 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011366">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011366</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:21448901</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:31980914</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1047</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/368</obo:IAO_0000233>
        <obo:OGG_0000000006>1485</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>1047</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CTAG1B</rdfs:comment>
        <rdfs:label>cancer subunit NY-ESO-1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011367 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011367">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011367</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1048</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/314</obo:IAO_0000233>
        <obo:OGG_0000000006>13805</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>1048</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Eng</rdfs:comment>
        <rdfs:label>cancer DNA vaccine encoding Endoglin Boosted with recombinant Endoglin Protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011368 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011368</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:10678354</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:8363286</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1049</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/345</obo:IAO_0000233>
        <obo:OGG_0000000006>14972</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0060058"/>
        <obo:VO_0001818>1049</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: H2-K1</rdfs:comment>
        <rdfs:label>Cancer recombinant vector vaccine encoding H-2Kb</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011369 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011369">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011369</metadata:prefixIRI>
        <obo:IAO_0000115>An xenogenic DNA vaccine encoding human TEM8 carried by attenuated Salmonella typhimurium to help reduce tumor growth and suppress angiogenesis in the tumors.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:19609240</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1046</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001818>1046</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>cancer DNA vaccine encoding TEM8</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011370 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011370">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005429"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011370</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:10881691</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:19188665</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1064</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/319</obo:IAO_0000233>
        <obo:OGG_0000000006>4072</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_3571"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>1064</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: EPCAM</rdfs:comment>
        <rdfs:label>Cancer EPCAM protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011371 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011371">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005428"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011371</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:19034678</obo:IAO_0000119>
        <obo:IAO_0000119>PMID:32164575</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1066</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/371</obo:IAO_0000233>
        <obo:OGG_0000000006>7422</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000532"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1319"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>1066</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: VEGFA</rdfs:comment>
        <rdfs:label>Cancer VEGFA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011372 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011372">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011372</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1058</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001818>1058</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>cancer retroviral vector vaccine encoding Cd40lg</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011373 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011373">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011373</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:/7533183</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1059</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/317</obo:IAO_0000233>
        <obo:OGG_0000000006>12524</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000344"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>1059</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: Cd86</rdfs:comment>
        <rdfs:label>Cancer DNA Vaccine pLXSHDmB7-2 encoding Cd86</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011374 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011374">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001362"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011280"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011374</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1054</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011280"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1205"/>
        <obo:VO_0001818>1054</obo:VO_0001818>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Phleum pratense allergy Phl p 12 subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011375 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011375">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000925"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011027"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5865"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011375</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. bovis GST-12D3</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=791</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011027"/>
        <obo:VO_0001818>791</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5865"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Babesia bovis GST-12D3 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011377 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011377">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011036"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011377</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pertussis BrkA protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=796</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011036"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>796</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis BrkA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011378 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011378">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012161"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011051"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011378</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=825</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011051"/>
        <obo:VO_0001818>825</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11901"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine leukemia virus DNA vaccine encoding Env</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011379 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011379">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012161"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011050"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011379</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011050"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11901"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine leukemia virus DNA vaccine encoding Tax</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011380 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011380">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001225"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010908"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011380</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. abortus DNA vaccine encoding RplL and Omp16</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=831</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010908"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11077"/>
        <obo:VO_0001818>831</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_235"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Brucella abortus DNA vaccine encoding RplL and Omp16</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011381 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011381">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011041"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011381</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=821</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011041"/>
        <obo:VO_0001818>821</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 DNA vaccine AdCMVgD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011382 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011382">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011382</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=823</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011043"/>
        <obo:VO_0001818>823</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 DNA vaccine AdCMVgC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011383 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011383">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000987"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011042"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011383</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=824</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011042"/>
        <obo:VO_0001818>824</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 GPI protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011384 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011384">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011020"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011384</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>A. pleuropneumoniae ApxIa and ApxIIa protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=784</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011020"/>
        <obo:VO_0001818>784</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Actinobacillus pleuropneumoniae ApxIa and ApxIIa protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011385">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001130"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011385</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000118>A. pleuropneumoniae HS93C-Ampr</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=786</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>786</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_715"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae</rdfs:comment>
        <rdfs:label>Actinobacillus pleuropneumoniae HS93C-Ampr</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011386">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000820"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001217"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011024"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011386</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=788</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011024"/>
        <obo:VO_0001818>788</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_645"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>The aroA gene was inactivated by inserting a fragment expressing kanamycin resistance within the coding sequence and challenged in fish. The LD50 for unvaccinated fish was 71. In contrast, the LD50 was 1.8 x 104 in fish vaccinated once and 3 x 105 in fish vaccinated twice</rdfs:comment>
        <rdfs:label>A. salmonicida live-attenuated vaccine encoding AroA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011387 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011387">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000726"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010859"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011387</metadata:prefixIRI>
        <obo:IAO_0000115>An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus NP protein.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>NP-VRP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=443</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010859"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4325"/>
        <obo:VO_0001818>443</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NP-VRP vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011388 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011388">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000767"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011234"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_780"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011388</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1044</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011234"/>
        <obo:VO_0001818>1044</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_780"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rickettsia rickettsii vaccine using M. vaccae expressing R. rickettsii OmpA Protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011389 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011389">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000484"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000767"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011235"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_780"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011389</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1045</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000636"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011235"/>
        <obo:VO_0001818>1045</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_780"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rickettsia DNA vaccine encoding OmpB Protein boosted with recombinant OmpB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011391 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011391">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011033"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011391</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pertussis DNA vaccine encoding Prn</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=808</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011033"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>808</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis DNA vaccine encoding Prn</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011392 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011392">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012162"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011165"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011392</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=993</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011165"/>
        <obo:VO_0001818>993</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Virus Vaccine rFPV/gI</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011393 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011393">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012162"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011164"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011393</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=994</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011164"/>
        <obo:VO_0001818>994</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s Disease Virus Vaccine rFPV/gB1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011394 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011394">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012163"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011163"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011394</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=997</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011163"/>
        <obo:VO_0001818>997</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg Virus Nucleoprotein Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011395 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011395">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011105"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011395</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=986</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011105"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001818>986</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus E7 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011396 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011396">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011241"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011396</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum Hsp90 Protein Subunit Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=987</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011241"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>987</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum Hsp90 protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011397 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011397">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011106"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011397</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=988</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011106"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001818>988</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus L2 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011398 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011398">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011109"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011398</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=989</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011109"/>
        <obo:VO_0001818>989</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>IHNV DNA vaccine pIHNw-G</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011399 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011399">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012166"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11588"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011399</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=990</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011319"/>
        <obo:VO_0001818>990</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11588"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rift Valley Fever Virus DNA Vaccine encoding N Protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011400 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011400">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011088"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011400</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=949</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011088"/>
        <obo:VO_0001818>949</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Puumala virus PUUVsSgp1 (NP) protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011401 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011401">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011086"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011401</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=950</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011086"/>
        <obo:VO_0001818>950</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Sin Nombre virus DNA vaccine encoding G1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011402 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011402">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011085"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011402</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=951</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011085"/>
        <obo:VO_0001818>951</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Seoul virus vaccine rCAV-2-Gc</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011403 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011403">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011089"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011403</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=952</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011089"/>
        <obo:VO_0001818>952</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Topografov virus N protein vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0011404 -->

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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011404</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=968</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011094"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001818>968</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B virus DNA vaccine pVAX-PS</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011405 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011405</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=969</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011100"/>
        <obo:VO_0001818>969</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus type 2 DNA vaccine encoding ICP27</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011406 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011406</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=970</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011097"/>
        <obo:VO_0001818>970</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus type 2 DNA vaccine encoding GB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011407 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011407</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=971</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>971</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>NIpah Virus G and F Proteins subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011408 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011408</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=972</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>972</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus type 1 DNA vaccine encoding GC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011409 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012170"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011409</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=963</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>963</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052223"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hendra virus G protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011410 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011410</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=964</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>964</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis DNA vaccine encoding Ag85B protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011411 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011411</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=965</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>965</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B virus DNA vaccine encoding HBVgp2 pre-S1/pre-S2/S</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011412 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011412</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>M. tuberculosis Mtb72F protein subunit vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=967</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011173"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>967</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis Mtb72F protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011413 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011413">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011413</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pertussis DNA vaccine encoding TcfA</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis DNA vaccine encoding TcfA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011414 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011414">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012171"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011326"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011414</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. histolytica CEL-170/4 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=918</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011326"/>
        <obo:VO_0001818>918</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Entamoeba histolytica CEL-170/4 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011415 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011415">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011415</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum Subunit SE36 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=919</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011210"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>919</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum subunit SE36 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011416 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011416">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012171"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011324"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011416</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. histolytica SREHP protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=920</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011324"/>
        <obo:VO_0001818>920</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Entamoeba histolytica SREHP protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011417 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011417">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010991"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011417</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=921</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010991"/>
        <obo:VO_0001818>921</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli C3389 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011418 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011418">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011223"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011418</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum Pfen Protein Subunit Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=922</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>922</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum Pfen protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011419 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011419">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000656"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011419</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=973</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        <obo:VO_0001818>973</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560602"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mumps HN protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011420 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011420">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012168"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011102"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011420</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=974</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>974</obo:VO_0001818>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus type 2 vaccine using phage displaying GG protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011421 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011421</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=975</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>975</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus type 1 DNA vaccine encoding GD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011422 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011422</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=976</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8622"/>
        <obo:VO_0001818>976</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Measles Virus vaccine VEE/SIN-H+F</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011423 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011423">
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011423</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Rebecca Racz</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=977</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011104"/>
        <obo:VO_0001818>977</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:comment>An HSV-1 gE (Us8) deletion strain, NS-gEnull, was used as a live attenuated vaccine. After HSV-1 challenge, latent virus was recovered by DRG explant cocultures from &lt;10% of vaccinated mice compared with 100% of mock-vaccinated mice</rdfs:comment>
        <rdfs:label>Herpes simplex virus type 1 DNA vaccine encoding GE</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011424 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011424">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011424</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. pneumoniae DNA vaccine encoding PknD</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=887</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>887</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83558"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila pneumoniae DNA vaccine encoding PknD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011425 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011425</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. pneumoniae DNA vaccine encoding Ssb</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=888</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>888</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83558"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila pneumoniae DNA vaccine encoding Ssb</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011426 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011426</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. psittaci DNA vaccine pcDNA1/MOMP</obo:IAO_0000118>
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        <obo:VO_0001818>889</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila psittaci DNA vaccine pcDNA2/MOMP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011427 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011427</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=890</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>890</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Classical swine fever virus vaccine VAC-E0</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011428 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011428</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. abortus DNA vaccine encoding GatC</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=878</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>878</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus DNA vaccine encoding GatC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011429 -->

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        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011429</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. abortus DNA vaccine encoding OmlA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=879</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>879</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus DNA vaccine encoding OmlA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011430 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011430</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. abortus DNA vaccine encoding MOMP</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=880</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010881"/>
        <obo:VO_0001818>880</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus DNA vaccine encoding MOMP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011431 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011431">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011058"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011431</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. abortus DNA vaccine Pomp90A</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=881</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011058"/>
        <obo:VO_0001818>881</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus DNA vaccine Pomp90A</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011432 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011432">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012173"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010884"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83558"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011432</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. pneumoniae CopN protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=882</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010884"/>
        <obo:VO_0001818>882</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83558"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila pneumoniae CopN protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011433 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011433">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007660"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011433</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:label>prostate cancer DNA vaccine encoding prostatic acid phosphatase (PAP)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011434 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011434">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011434</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. pneumoniae DNA vaccine encoding FabD</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=884</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>884</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83558"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila pneumoniae DNA vaccine encoding FabD</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011435 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011435">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012173"/>
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            </owl:Restriction>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010883"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011435</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. pneumoniae LcrE protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=885</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>885</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83558"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila pneumoniae LcrE protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011436 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011436">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012175"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011436</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pseudomallei Subunit LolC Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=860</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010921"/>
        <obo:VO_0001818>860</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Burkholderia pseudomallei subunit LolC protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011437 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011437">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012176"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010892"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011437</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum RplF protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=861</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010892"/>
        <obo:VO_0001818>861</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum RplF protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011438 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011438">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012175"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011438</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pseudomallei Subunit PotF Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=862</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010922"/>
        <obo:VO_0001818>862</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Burkholderia pseudomallei subunit PotF protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011439 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011439</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. yoelii MSP1 and MSP4/5 Proteins Subunit Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=984</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011236"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>984</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii MSP1 and MSP4/5 proteins subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011440 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011440">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000087"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011440</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>P. falciparum MSP3 Protein Subunit Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=985</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011220"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12365"/>
        <obo:VO_0001818>985</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum MSP3 protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011441 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011441">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012177"/>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011151"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011441</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1035</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011151"/>
        <obo:VO_0001818>1035</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lassa Virus Nucleoprotein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011442 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011442">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010990"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011442</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=923</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010990"/>
        <obo:VO_0001818>923</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli C4424 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011443 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011443">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010984"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011443</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=924</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010984"/>
        <obo:VO_0001818>924</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli Hma protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011444 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011444">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010985"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011444</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=925</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010985"/>
        <obo:VO_0001818>925</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli IreA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011445 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011445">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000628"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010986"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011445</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=926</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010986"/>
        <obo:VO_0001818>926</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_562"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>E. coli IutA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011446 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011446">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000152"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011075"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011446</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>F. tularensis GroEL protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=928</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011075"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2123"/>
        <obo:VO_0001818>928</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis GroEL protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011447 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011447">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011447</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>F. tularensis DNA vaccine rLm/iglC</obo:IAO_0000118>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0000431"/>
        <rdfs:label>obsolete Francisella tularensis DNA vaccine rLm/iglC</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011448 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011448">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001137"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011064"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011448</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. tenella vaccine rBCG pMV361-Rho</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=912</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011064"/>
        <obo:VO_0001818>912</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria tenella vaccine rBCG pMV361-Rho</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011449 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011449">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001137"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011449</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. tenella DNA vaccine pcDNA-TA4-IL-2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=913</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011065"/>
        <obo:VO_0001818>913</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria tenella DNA vaccine pcDNA-TA4-IL-2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011450 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012171"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011322"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011450</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. histolytica Eh29 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=915</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011322"/>
        <obo:VO_0001818>915</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Entamoeba histolytica Eh29 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011451 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011451">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012171"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011323"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011451</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. histolytica Gal/GalNAc lectin protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=916</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011323"/>
        <obo:VO_0001818>916</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Entamoeba histolytica Gal/GalNAc lectin protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011452 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011452">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000725"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011315"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011452</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=853</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011315"/>
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        <obo:VO_0001818>853</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue vaccine using Vaccinia virus expressing prM protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011453 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011453">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012176"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010890"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011453</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum MOMP protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=854</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010890"/>
        <obo:VO_0001818>854</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum MOMP protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011454 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011454">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000725"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011454</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=855</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011312"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
        <obo:VO_0001818>855</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue DNA vaccine encoding NS1 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011455 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011455">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000725"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011455</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=856</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011316"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12205"/>
        <obo:VO_0001818>856</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue vaccine using Vaccinia virus expressing M protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011456 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011456">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012176"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010893"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011456</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum PmpE/F-2 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=857</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010893"/>
        <obo:VO_0001818>857</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum PmpE/F-2 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011457 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011457">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011457</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=858</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>858</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12637"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dengue subunit E protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011458 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011458">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012176"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011458</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum PmpG-1 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=859</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010891"/>
        <obo:VO_0001818>859</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum PmpG-1 protein vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0011459 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011459</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=847</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011052"/>
        <obo:VO_0001818>847</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine distemper virus DNA vaccine encoding HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011460 -->

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        </rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011460</metadata:prefixIRI>
        <obo:IAO_0000115>a Coccidioides vaccine that contains C. posadasii PMP1 protein</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. posadasii subunit PMP1 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=848</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>848</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5500"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coccidioides posadasii subunit PMP1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011461 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011461</metadata:prefixIRI>
        <obo:IAO_0000115>a Coccidioides vaccine that contains C. posadasii DNA vaccine encoding PRA protein</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. posadasii DNA Vaccine encoding PRA protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=849</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011333"/>
        <obo:VO_0001818>849</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5500"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coccidioides posadasii DNA vaccine encoding PRA protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011462 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011462</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=850</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>850</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine parvovirus DNA vaccine pGT36VP1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011463 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011463</metadata:prefixIRI>
        <obo:IAO_0000115>a Coccidioides vaccine that contains C. immitis subunit URE protein</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. immitis subunit URE protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=851</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>851</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5500"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coccidioides immitis subunit URE protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011464 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012180"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011464</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=852</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>852</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine parvovirus CPMV-PARVO1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011465 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011465</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=901</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>901</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_205488"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Ebola virus DNA vaccine encoding ZEBOV GP and SEBOV GP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011466 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011466</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0001818>902</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella flexneri Invaplex 24 subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011467 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011467</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. maxima Gam82 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=903</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011062"/>
        <obo:VO_0001818>903</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5804"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria maxima Gam82 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011468 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011468">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010994"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010995"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011468</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>S. flexneri Invaplex 50 Subunit Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=904</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010994"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010995"/>
        <obo:VO_0001818>904</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_623"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Shigella flexneri Invaplex 50 subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011469 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011469">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011469</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. tenella DNA vaccine proIE</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=905</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011066"/>
        <obo:VO_0001818>905</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria tenella DNA vaccine proIE</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011470 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011470">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001137"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011470</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. tenella GX3262 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=907</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011067"/>
        <obo:VO_0001818>907</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria tenella GX3262 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011471 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011471">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011471</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. tenella DNA vaccine EtMIC2</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=909</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011063"/>
        <obo:VO_0001818>909</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria tenella DNA vaccine EtMIC2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011472 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011472">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011064"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011472</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>E. tenella DNA vaccine rBCG pMV261-Rho</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=910</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011064"/>
        <obo:VO_0001818>910</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5802"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Eimeria tenella DNA vaccine rBCG pMV261-Rho</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011473 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011473">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012162"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011473</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=397</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>397</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vaxxitek HVT+IBD vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011474 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000446"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001222"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011474</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=398</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9031"/>
        <obo:VO_0001818>398</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle disease virus vaccine by Dow AgroSciences</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011475 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011475">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001061"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5875"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011475</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=427</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:VO_0001818>427</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5875"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Theileria parva vaccine by Centre for Ticks and Tickborne Disease, Malawi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011476 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011476">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000909"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011476</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=428</obo:IAO_0000119>
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        <obo:VO_0001818>428</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5874"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Theileria annulata vaccine by Local veterinary institutes</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011477 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011477">
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011335"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011477</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>H. pylori DNA vaccine encoding UreB</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=960</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011335"/>
        <obo:VO_0001818>960</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori DNA vaccine encoding UreB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011478 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011478">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000077"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011175"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011478</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>M. tuberculosis DNA Vaccine APADNA priming and APAMVA boosting</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=961</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011175"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001818>961</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1773"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycobacterium tuberculosis DNA vaccine APADNA priming and APAMVA boosting</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011479 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011479">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011341"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011479</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>H. pylori VacA protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=962</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011341"/>
        <obo:VO_0001818>962</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori VacA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011480 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011480">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000667"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011107"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011480</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=981</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011107"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11166"/>
        <obo:VO_0001818>981</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10566"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human papillomavirus DNA vaccine pNGVL4a-E6/opt</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011481 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011481">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001524"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011243"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011481</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=982</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011243"/>
        <obo:VO_0001818>982</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_85708"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>PCV2 DNA vaccine encoding ORF2 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011482 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011482">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000586"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010436"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010445"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010447"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011482</metadata:prefixIRI>
        <obo:IAO_0000115>A multivalent vaccine against tetanus, diphtheria, and poliomyelitis.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Ningxian Fan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Td Polio Adsorbed</obo:IAO_0000118>
        <obo:IAO_0000118>Tetanus and Diphtheria Toxoids Adsorbed and Inactivated Poliomyelitis Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=628</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=629</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=630</obo:IAO_0000119>
        <obo:IAO_0000119>WEB: https://www.vaccineshoppecanada.com/document.cfm?file=td_polio_adsorbed_e.pdf</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11405"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_4953"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>628</obo:VO_0001818>
        <obo:VO_0001818>629</obo:VO_0001818>
        <obo:VO_0001818>630</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_138950"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1513"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1717"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Td Polio Adsorbed vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011483 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011483">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011483</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0011482"/>
        <rdfs:comment>This term is obsolete since there is another term with the same name.</rdfs:comment>
        <rdfs:label>obsolete Td Polio Adsorbed</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011484 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011484">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011484</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0011482"/>
        <rdfs:comment>This term is obsolete since there is another term with the same name.</rdfs:comment>
        <rdfs:label>obsolete Td Polio Adsorbed</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011485 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011485">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011047"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011485</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. jejuni FspA1 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=841</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011047"/>
        <obo:VO_0001818>841</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter jejuni FspA1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011486 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011486">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011486</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=842</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011320"/>
        <obo:VO_0001818>842</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS subunit spike protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011487 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011487">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011049"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011487</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. jejuni FspA2 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=843</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011049"/>
        <obo:VO_0001818>843</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter jejuni FspA2 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011488 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011488">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011045"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011488</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. jejuni DNA vaccine pcDNA3.1(+)-peblA</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=844</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011045"/>
        <obo:VO_0001818>844</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter jejuni DNA vaccine pcDNA3.1(+)-peblA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011489 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011489">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012178"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011053"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011489</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=845</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011053"/>
        <obo:VO_0001818>845</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Canine distemper virus DNA vaccine encoding F and HA</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011490 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011490">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012179"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5500"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011490</metadata:prefixIRI>
        <obo:IAO_0000115>a Coccidioides vaccine that contains C. posadasii subunit GEL1 protein</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. posadasii subunit GEL1 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=846</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
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        <obo:VO_0001818>846</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5500"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coccidioides posadasii subunit GEL1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011491 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011491">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012184"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5691"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011491</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. brucei DNA Vaccine encoding TSA protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=836</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011338"/>
        <obo:VO_0001818>836</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5691"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma brucei DNA vaccine encoding TSA protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011492 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011492">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012184"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011334"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5691"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011492</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. brucei Subunit p15 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=837</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011334"/>
        <obo:VO_0001818>837</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5691"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma brucei subunit p15 Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011493 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011493">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011046"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011493</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. jejuni MBP-FlaA protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=838</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011046"/>
        <obo:VO_0001818>838</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter jejuni MBP-FlaA protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011494 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011494">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001061"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5875"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011494</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. parva Subunit p67 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=839</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011183"/>
        <obo:VO_0001818>839</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5875"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Theileria parva Subunit p67 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011495 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011495">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012182"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011048"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011495</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. jejuni FlaC protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=840</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011048"/>
        <obo:VO_0001818>840</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter jejuni FlaC protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011498 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011498">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000765"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011030"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011498</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pertussis FhaB and 69 kDa OMP protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=805</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011030"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_1116"/>
        <obo:VO_0001818>805</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_520"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bordetella pertussis FhaB and 69 kDa OMP protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011499 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011499">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012185"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010916"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011499</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>H. influenzae Hap protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=936</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010916"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001818>936</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae Hap protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011500 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011500">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000665"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011147"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011500</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1033</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011147"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001818>1033</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus DNA vaccine encoding NS1 (pUSK-NS1)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011501 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011501">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000665"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011148"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011501</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1034</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011148"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001818>1034</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus DNA vaccine pUJENS3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011502 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011502">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012160"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011309"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011502</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. parvum DNA vaccine encoding CP15/60</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=900</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011309"/>
        <obo:VO_0001818>900</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5807"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Cryptosporidium. parvum DNA vaccine encoding CP15/61</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011503 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011503">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012186"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011321"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011503</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Y. enterocolititica Subunit V Antigen Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=896</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011321"/>
        <obo:VO_0001818>896</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia enterocolititica Subunit V Antigen Protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011504 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011504">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011504</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. botulinum FHc protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=897</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010901"/>
        <obo:VO_0001818>897</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Clostridium botulinum FHc protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011505 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011505">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012188"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011306"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011505</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=898</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011306"/>
        <obo:VO_0001818>898</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>WEEV DNA vaccine encoding 6K-E1 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011506 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011506">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012188"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010897"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011506</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=899</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010897"/>
        <obo:VO_0001818>899</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>WEEV Subunit E2 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011507 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011507">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0005425"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011507</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:C5187854</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=891</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/367</obo:IAO_0000233>
        <obo:OGG_0000000006>7015</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000631"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000887"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10283"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>891</obo:VO_0001818>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: TERT</rdfs:comment>
        <rdfs:label>Cancer Subunit GV1001 Protein Vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011508 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011508">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010897"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011508</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=892</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010897"/>
        <obo:VO_0001818>892</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Classical swine fever virus vaccine VAC-E2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011509 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011509">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001012"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010899"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011509</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=893</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010899"/>
        <obo:VO_0001818>893</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Classical swine fever virus E1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011510 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011510">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0007657"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0000547"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011510</metadata:prefixIRI>
        <obo:IAO_0000117>Eliyas Asfaw</obo:IAO_0000117>
        <obo:IAO_0000117>Ibrahim Seleznev</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>PMID:wler=tru</obo:IAO_0000119>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=894</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/366</obo:IAO_0000233>
        <obo:OGG_0000000006>1084</obo:OGG_0000000006>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000562"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:VO_0000547 rdf:resource="http://purl.obolibrary.org/obo/VO_0000340"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_162"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0001818>894</obo:VO_0001818>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>cancer vaccine</oboInOwl:inSubset>
        <rdfs:comment>Gene name: CEACAM3</rdfs:comment>
        <rdfs:label>Cancer Subunit DC (Tat-CEA) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011511 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011511">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012187"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010904"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011511</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. botulinum DNA vaccine pSCARSBHc</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010904"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Clostridium botulinum DNA vaccine pSCARSBHc</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011512 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011512">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012167"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010960"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011512</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=954</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0010960"/>
        <obo:VO_0001818>954</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Dobrava-Belgrade virus S nucleocapsid protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011513 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011513">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011339"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011513</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>H. pylori catalase protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=955</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011339"/>
        <obo:VO_0001818>955</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori catalase protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011514 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011514">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012181"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011337"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011514</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>H. pylori NAP protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=958</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011337"/>
        <obo:VO_0001818>958</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori NAP protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011515 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011515">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000949"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001077"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011178"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011515</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>M. gallisepticum TM-1 Protein Subunit Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=959</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011178"/>
        <obo:VO_0001818>959</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2096"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Mycoplasma gallisepticum TM-1 protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011516 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011516">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000665"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011145"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011516</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1027</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011145"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_10844"/>
        <obo:VO_0001818>1027</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus vaccine BV-G-E</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011517 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011517">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000909"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011187"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5874"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011517</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. annulata Subunit SPAG-1 Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=873</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011187"/>
        <obo:VO_0001818>873</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5874"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Theileria annulata Subunit SPAG-1 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011518 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011518">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001085"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010882"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011518</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. abortus DNA vaccine encoding DnaK</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=874</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010882"/>
        <obo:VO_0001818>874</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus DNA vaccine encoding DnaK</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011519 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011519">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011056"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011519</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. abortus DNA vaccine encoding DnaX</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=875</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011056"/>
        <obo:VO_0001818>875</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus DNA vaccine encoding DnaX</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011520 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011520">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010879"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011520</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. abortus DNA vaccine encoding GatA/GatB</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=876</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010879"/>
        <obo:VO_0001818>876</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus DNA vaccine encoding GatA/GatB</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011521 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011521">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011340"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011521</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii Subunit Rop2-Hsp83 Fusion Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=866</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011340"/>
        <obo:VO_0001818>866</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii Subunit Rop2-Hsp83 fusion protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011522 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011522">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012176"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010886"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011522</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum DNA vaccine encoding TC0757</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=867</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010886"/>
        <obo:VO_0001818>867</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum DNA vaccine encoding TC0757</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011523 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011523">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011523</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii DNA vaccine pcDNA3-MIC3</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=868</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011174"/>
        <obo:VO_0001818>868</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine pcDNA3-MIC3</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011524 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011524">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012176"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010888"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011524</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum DNA vaccine encoding TC0767/768</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=869</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010888"/>
        <obo:VO_0001818>869</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum DNA vaccine encoding TC0767/768</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011525 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011525">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000994"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011000"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011525</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>T. gondii DNA Vaccine encoding SAG1 Protein</obo:IAO_0000118>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011000"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5811"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Toxoplasma gondii DNA vaccine encoding SAG1 protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011526 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011526">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001085"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011059"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011526</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. abortus DNA vaccine encoding CAB049</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=871</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>871</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus DNA vaccine encoding CAB049</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011527 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011527">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001085"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011061"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011527</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. abortus DNA vaccine encoding CAB613</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=872</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>872</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83555"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila abortus DNA vaccine encoding CAB613</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011528 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011528">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011528</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1023</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>1023</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>infleunza virus DNA vaccine encoding NP from Influenza A virus (A/chicken/Henan/12/2004(H5N1))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011529 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011529">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011529</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1024</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>1024</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding NP from influenza A virus (A/chicken/Hubei/489/2004(H5N1))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011530 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011530">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011530</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani DNA vaccine encoding KMP-11</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1025</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011157"/>
        <obo:VO_0001818>1025</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani DNA vaccine encoding KMP-11</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011531 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011531">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000642"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011531</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1026</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>1026</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus NP protein vaccine (influenza A virus (A/nt/60/1968(H3N2)))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011532 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011532">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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            </owl:Restriction>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011532</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani gp63 Protein Subunit Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1022</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000624"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011158"/>
        <obo:VO_0001818>1022</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <obo:VO_0003390 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani gp63 protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011533 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011533</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum DNA vaccine encoding TC0439</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=864</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010887"/>
        <obo:VO_0001818>864</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum DNA vaccine encoding TC0439</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011534 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010885"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011534</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. muridarum DNA vaccine encoding TC0512</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=865</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0010885"/>
        <obo:VO_0001818>865</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum DNA vaccine encoding TC0512</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011535 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000654"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011535</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=978</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>978</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Measles Virus vaccine VVN</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011536 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000654"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011536</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=979</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>979</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Measles Virus vaccine VVP</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011537 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000654"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011537</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=980</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>980</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11234"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Measles Virus vaccine VVM</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011538 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011538">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012175"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011538</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>B. pseudomallei DNA vaccine encoding Flagellin Protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=863</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011303"/>
        <obo:VO_0001818>863</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Burkholderia pseudomallei DNA vaccine encoding Flagellin protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011539 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001142"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011539</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani ORFF Protein Subunit Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1017</obo:IAO_0000119>
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        <obo:VO_0001818>1017</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5661"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani ORFF protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011540 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011540</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1018</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>1018</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding NA from influenza B virus (B/Ibaraki/2/85)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011541 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011541</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1019</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000623"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001818>1019</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza virus DNA vaccine encoding NA from influenza A virus (A/chicken/Henan/12/2004(H5N1))</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011542 -->

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            </owl:Restriction>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003390"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011542</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>L. donovani DNA Vaccine encoding NH36 Protein</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1020</obo:IAO_0000119>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011161"/>
        <obo:VO_0001818>1020</obo:VO_0001818>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania donovani DNA vaccine encoding NH36 Protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011543 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011543</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=945</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:RO_0002292 rdf:resource="http://purl.obolibrary.org/obo/VO_0011087"/>
        <obo:VO_0001818>945</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Sin Nombre virus DNA vaccine encoding SNVsSgp1 (NP)</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011544 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011544</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>S. equi Subunit EAG, FNZ and SFS Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=832</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>832</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1336"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus equi Subunit EAG, FNZ and SFS protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011545 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011545</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>C. jejuni DNA vaccine pcDNA3.1(+)-cadF</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=833</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>833</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter jejuni DNA vaccine pcDNA3.1(+)-cadF</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011546 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011546">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011546</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>S. equi Subunit CNE Protein Vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=834</obo:IAO_0000119>
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        <obo:VO_0001818>834</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1336"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Streptococcus equi Subunit CNE protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011548 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011548</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=930</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>930</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_263"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Francisella tularensis DNA vaccine pTUL4-15</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011549 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000534"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011549</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=931</obo:IAO_0000119>
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        <obo:VO_0001818>931</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5820"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Plasmodium berghei CS protein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011550 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011550</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>932</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5741"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Giardia duodenalis DNA vaccine encoding CWP2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011551 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011551">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012185"/>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011551</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>H. influenzae D15 protein vaccine</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=933</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0001818>933</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae D15 protein vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011552 -->

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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011552</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=934</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>934</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2560319"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Newcastle Disease Virus HN glycoprotein subunit vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011553 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011553">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011553</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=816</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>816</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies DNA vaccine encoding Rabies virus Glycoprotein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011554 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011554">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011554</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=817</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>817</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 DNA vaccine tgD-VP22</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011555 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011555">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000650"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011555</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=818</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>818</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rabies vaccine rVac-N</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011556 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011556">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000635"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000768"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011556</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Vivotif L</obo:IAO_0000118>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=645</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001818>645</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_590"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Vivotif L vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011557 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0011557">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000032"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0011557</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>VIOLIN: https://violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=815</obo:IAO_0000119>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000208"/>
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        <obo:VO_0001818>815</obo:VO_0001818>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10320"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Bovine herpesvirus 1 DNA vaccine pRSV-gC</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0011558 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0011561 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0011562 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0011564 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0011565 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0012158 -->

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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012158</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Leishmania amazonensis.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Leishmania amazonensis</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5659"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania amazonensis vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012159 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012159">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
                    </owl:Restriction>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000762"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012159</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Leishmania infantum.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Leishmania infantum</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5671"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Leishmania infantum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012160 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012160">
        <owl:equivalentClass>
            <owl:Class>
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                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5807"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5807"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012160</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Cryptosporidium parvum.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Cryptosporidium parvum</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5807"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Cryptosporidium parvum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012161 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012161">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11901"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11901"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012161</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Bovine Leukemia virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>bovine leukemia virus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11901"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>bovine leukemia virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012162">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000727"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012162</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Marek&apos;s disease virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Marek&apos;s; disease virus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10390"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marek&apos;s disease virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012163 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012163">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012163</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Marburg Virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Marburg Virus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_186537"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Marburg Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012165 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012165">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012165</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Infectious Hematopoietic Necrosis Virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Infectious Hematopoietic Necrosis Virus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11290"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Infectious Hematopoietic Necrosis Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012166 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012166">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11588"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11588"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012166</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Rift Valley Fever virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Rift Valley Fever virus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11588"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rift Valley Fever virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012167 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012167">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012167</metadata:prefixIRI>
        <obo:IAO_0000115>Viral vaccine that protects against Hantavirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Hantavirus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1980442"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hantavirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012168 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012168">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000727"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012168</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Herpes simplex virus type 1 and 2.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Herpes simplex virus type 1 and 2</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10298"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Herpes simplex virus type 1 and 2 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012169 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012169">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012169</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Nipah virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052225"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Nipah virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012170 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012170">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052223"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052223"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012170</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Hendra virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Hendra virus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052223"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hendra virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012171 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012171">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012171</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Entamoeba histolytica.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Entamoeba histolytica</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5759"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Entamoeba histolytica vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012173 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012173">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000573"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83558"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012173</metadata:prefixIRI>
        <obo:IAO_0000115>A Chlamydia vaccine that protects against Chlamydophila pneumoniae.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83558"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila pneumoniae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012174 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012174">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000573"/>
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            <owl:Restriction>
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                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012174</metadata:prefixIRI>
        <obo:IAO_0000115>A Chlamydia bacterial vaccine against Chlamydophila psittaci infection</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83554"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydophila psittaci vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012175 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012175">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003532"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012175</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Burkholderia pseudomallei.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Burkholderia pseudomallei</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_28450"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Burkholderia pseudomallei vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012176 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012176">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000573"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012176</metadata:prefixIRI>
        <obo:IAO_0000115>A Chlamydia vaccine that protects against Chlamydia muridarum.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Chlamydia muridarum</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_83560"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Chlamydia muridarum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012177 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012177">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012177</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Lassa Fever Virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Lassa Fever Virus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052310"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Lassa Fever Virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012178">
        <owl:equivalentClass>
            <owl:Class>
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                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003543"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012178</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Canine distemper virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_3052342"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>canine distemper virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012179 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012179">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000267"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5500"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000267"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5500"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012179</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Coccidioides spp.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Coccidioides spp. vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5500"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Coccidioides vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012180 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012180">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012180</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Canine parvovirus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Canine parvovirus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10788"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>canine parvovirus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012181">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000165"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012181</metadata:prefixIRI>
        <obo:IAO_0000115>Vaccine that protects against Helicobacter pylori infection.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Helicobacter pylori</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_210"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Helicobacter pylori vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012182">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000568"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012182</metadata:prefixIRI>
        <obo:IAO_0000115>A Campylobacter vaccine that protects against Campylobacter jejuni.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Campylobacter jejuni vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012183 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012183">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_2901879"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004897"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_694009"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012183</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against SARS-CoV.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>SARS-CoV vaccine</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_694009"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012184">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5691"/>
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                </owl:intersectionOf>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000417"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012184</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Trypanosoma brucei.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Trypanosoma brucei</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_5691"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Trypanosoma brucei vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012185">
        <owl:equivalentClass>
            <owl:Class>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
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                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000661"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012185</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Haemophilus influenzae.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080179"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_727"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012186 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012186">
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000601"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012186</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Yersinia enterocolitica.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Yersinia enterocolitica</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_150052"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yersinia enterocolitica vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012187 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012187">
        <owl:equivalentClass>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000639"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012187</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Clostridium botulinum .</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Clostridium botulinum</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1491"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Clostridium botulinum vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012188 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012188">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000609"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012188</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Western equine encephalomyelitis virus.</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>Western equine encephalomyelitis virus</obo:IAO_0000118>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11039"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Western equine encephalomyelitis virus vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012190 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012190">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003546"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0050175"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012190</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine that protects against Tick-borne Encephalitis Virus (TBEV).</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>tick-borne encephalitis vaccine</obo:IAO_0000118>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0050175"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11084"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Tick-borne Encephalitis Virus (TBEV) vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012212 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012212">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000177"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012212</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a Cancer vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0000177"/>
        <oboInOwl:hasAlternativeId>VO:0001236</oboInOwl:hasAlternativeId>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>cancer vaccine preparation</rdfs:label>
        <rdfs:seeAlso>VIOLIN Pathogen ID: 99</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012213 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012213">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000590"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0001362"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012213</metadata:prefixIRI>
        <obo:IAO_0000115>A vaccine preparation that results in the generation of a Allergy vaccine</obo:IAO_0000115>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:OBI_0000299 rdf:resource="http://purl.obolibrary.org/obo/VO_0001362"/>
        <oboInOwl:inSubset>vaccine preparation</oboInOwl:inSubset>
        <rdfs:label>allergy vaccine preparation</rdfs:label>
        <rdfs:seeAlso>VIOLIN Pathogen ID: 114</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012355 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012355">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012355</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Staphylococcus aureus protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012356 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012356">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012356</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Streptococcus agalactiae protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012357 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012357">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010752"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012357</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Streptococcus pyogenes protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012358 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012358">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010751"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012358</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Treponema pallidum protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012359">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010759"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012359</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>YopH from Y. pestis strain: CO92, biovar: Orientalis</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 51; NCBI Gene GI: 1172712; NCBI Protein GI: 16082755; NCBI Protein Accession: NP_395201; NCBITaxon: 214092</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012360 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012360">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012370"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012360</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>The oprF gene was cloned into plasmid vector pVR1020, and the plasmid vaccines were delivered to mice by biolistic (gene gun) intradermal inoculation. Following the initial immunization and two consecutive boosts, each at 2-week intervals, protection was demonstrated in a mouse model of chronic pulmonary infection by P. aeruginosa. Eight days postchallenge, both lungs were removed and examined. A significant reduction in the presence of severe macroscopic lesions, as well as in the number of bacteria present in the lungs, was seen [PubMed: 11292786].</rdfs:comment>
        <rdfs:label>OprF</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 843; NCBI Gene GI: 878442; NCBI Protein GI: 15596974; NCBI Protein Accession: NP_250468; NCBITaxon: 208964</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012361 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012361">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012370"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012361</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Burned Pseudomonas aeruginosa-infected mice immunized against PcrV, a type III virulence system translocating protein, showed significantly enhanced survival compared to controls [PubMed: 11500471].</rdfs:comment>
        <rdfs:label>PcrV</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 844; NCBI Gene GI: 882997; NCBI Protein GI: 15596903; NCBI Protein Accession: NP_250397; NCBITaxon: 208964</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012362 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012362">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012370"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012362</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant OprI protein was used to immunize mice, and was found to be protective against a challenge with a four- to fivefold 50% lethal dose of P. aeruginosa [PubMed: 2114360].</rdfs:comment>
        <rdfs:label>OprI</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 845; NCBI Gene GI: 879851; NCBI Protein GI: 15598049; NCBI Protein Accession: NP_251543; NCBITaxon: 208964</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012363 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012363">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010764"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012363</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>AY243312</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 68; NCBI Nucleotide GI: 29692106</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012364 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012364">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012364</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In mice, a primary vaccination with Ag85B-encoding plasmid DNA (DNA-85B) was protective against Mycobacterium tuberculosis (MTB) infection and associated with Ag85B-specific CD4+ T cells producing IFN-gamma and controlling intramacrophagic MTB growth [PubMed: 17250590].</rdfs:comment>
        <rdfs:label>Ag85B from M. tuberculosis H37Rv</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 118; NCBI Gene GI: 885785; NCBI Protein GI: 15609023; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012365 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012365">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012365</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>znuA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 228; NCBI Gene GI: 3341411; NCBI Protein GI: 62317941; NCBI Protein Accession: YP_223794; NCBITaxon: 262698</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012366 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012366">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012366</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intravenous vaccination with recombinant bacteria carrying expression plasmid for  MPB/MPT51 in BALB/c mice elicited significant protective responses, comparable to those evoked by a live Mycobacterium bovis BCG vaccine [PubMed: 15039321].</rdfs:comment>
        <rdfs:label>FbpD</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 814; NCBI Gene GI: 7562680; NCBI Protein GI: 224992215; NCBI Protein Accession: YP_002646905; NCBITaxon: 561275</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012367 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012367">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012367</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>DNA vaccines encoding secreted proteins Ag85B and MPT64 protect mice from the tuberculosis H37Rv strain [PubMed: 15498274]. 
*Note* MPT64 in combination with Ag85B was protective, DNA vaccine of just MPT64 was mildly protective in mice.</rdfs:comment>
        <rdfs:label>MPT64</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 815; NCBI Gene GI: 885925; NCBI Protein GI: 15609117; NCBI Protein Accession: NP_216496; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012368 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012368">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012368</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In a prophylactic vaccine model, immunization with the Mycobacterium tuberculosis protein ESAT-6 with LANAC adjuvant elicited significant protective immunity against aerosol challenge with virulent M. tuberculosis [PubMed: 16751377].</rdfs:comment>
        <rdfs:label>ESAT-6</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 816; NCBI Gene GI: 886209; NCBI Protein GI: 57117165; NCBI Protein Accession: YP_178023; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012369 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012369">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012369</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>DNA vaccines encoding  KatG antigen fused to TPA signal sequences evoked  a significant protective response in mice aerogenically challenged with low doses of Mycobacterium tuberculosis Erdman 17 to 21 days after the final immunization [PubMed: 10456931].</rdfs:comment>
        <rdfs:label>KatG</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 817; NCBI Gene GI: 885638; NCBI Protein GI: 15609045; NCBI Protein Accession: NP_216424; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012370 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012370">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012370</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice vaccinated with PstS-3 DNA demonstrated significant and sustained reduction in bacterial CFU numbers in spleen and lungs for 3 mo after M. tuberculosis challenge, as compared with CFU counts in mice vaccinated with control DNA [PubMed: 9916741].</rdfs:comment>
        <rdfs:label>PstS3</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 818; NCBI Gene GI: 885366; NCBI Protein GI: 57116798; NCBI Protein Accession: YP_177768; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012371 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012371">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012371</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A selection of previously identified protective Mycobacterium tuberculosis DNA vaccines were re-formulated as proteins and administered with a Th1-inducing adjuvant to help stimulate the relevant immune responses necessary for protection. One candidate (Rv1806-1807) induced protection in the guinea pig aerosol infection model 30 days post-challenge on the basis of reducing the bacterial burden of M. tuberculosis in the lungs [PubMed: 16520093].</rdfs:comment>
        <rdfs:label>PE20</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 819; NCBI Gene GI: 885537; NCBI Protein GI: 57116919; NCBI Protein Accession: YP_177843; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012372 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012372">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012372</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A selection of previously identified protective Mycobacterium tuberculosis DNA vaccines were re-formulated as proteins and administered with a Th1-inducing adjuvant to help stimulate the relevant immune responses necessary for protection. One candidate (Rv1806-1807) induced protection in the guinea pig aerosol infection model 30 days post-challenge on the basis of reducing the bacterial burden of M. tuberculosis in the lungs [PubMed: 16520093].</rdfs:comment>
        <rdfs:label>PPE31</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 820; NCBI Gene GI: 885072; NCBI Protein GI: 57116920; NCBI Protein Accession: YP_177653; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012373 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012373">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012373</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Purified preparations of HBHA were emulsified in a dimethyldioctadecylammonium bromide-monophosphoryl lipid A adjuvant and tested for the ability to reduce M. tuberculosis infection in the mouse aerosol challenge model for tuberculosis. The HBHA-containing vaccine gave a approximately 0.7-log reduction in CFU in both mouse lungs and spleens compared to adjuvant controls 28 days following challenge [PubMed: 15557600].</rdfs:comment>
        <rdfs:label>HBHA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 821; NCBI Gene GI: 5211814; NCBI Protein GI: 148660242; NCBI Protein Accession: YP_001281765; NCBITaxon: 25177</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012374 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012374">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012374</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>immunization with the soluble recombinant rMTB41 protein plus adjuvant, a regimen known to generate primarily CD4+ T cells, resulted in induction of protection comparable to BCG in two well-established animal models of tuberculosis (mice and guinea pigs) [PubMed: 15917115].</rdfs:comment>
        <rdfs:label>PPE14</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 822; NCBI Gene GI: 885069; NCBI Protein GI: 57116795; NCBI Protein Accession: YP_177765; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012375 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012375">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010758"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012375</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>GAPDH (Gap) associated with murine IL-12 gene in a DNA vaccine formulation partially protected mice against experimental infection [PubMed: 12171297].</rdfs:comment>
        <rdfs:label>Gap</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 823; NCBI Gene GI: 3340207; NCBI Protein GI: 62290600; NCBI Protein Accession: YP_222393; NCBITaxon: 262698</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012376 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012376">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012376</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>rHtrA was found to be very immunogenic and partially protective in both the passive infant rat model of bacteremia and the active chinchilla model of otitis media [PubMed: 9488373].</rdfs:comment>
        <rdfs:label>HtrA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 824; NCBI Protein GI: 2935168; NCBITaxon: 727</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012377 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012377">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010855"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012377</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Orogastric immunization of mice with recombinant H. pylori HspA proteins protected 80%  of animals from a challenge dose of 10^4 Helicobacter felis bacteria [PubMed: 7604021].</rdfs:comment>
        <rdfs:label>HspA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 825; NCBI Protein GI: 712830; NCBITaxon: 210</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012378 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012378">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010855"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012378</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Orogastric immunization of mice with recombinant H. pylori HspB proteins protected 70% of animals from a challenge dose of 10^4 Helicobacter felis bacteria [PubMed: 7604021].</rdfs:comment>
        <rdfs:label>HspB from Helicobacter pylori</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 826; NCBI Protein GI: 712831; NCBITaxon: 210</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012379 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012379">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010855"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012379</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice were immunised with the citrate synthase protein by intra-Peyer&apos;s patch immunisation. Pre-immunisation with the citrate synthase protein led to a 84-91% reduction in H. pylori infection compared to unimmunised controls [PubMed: 10378424].</rdfs:comment>
        <rdfs:label>GltA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 827; NCBI Protein GI: 2493711; NCBITaxon: 210</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012380 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012380">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010778"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012380</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Recombinant TbpA protein was used in a mouse intraperitoneal-infection model to determine their ability to protect against meningococcal infection and to induce cross-reactive and bactericidal antibodies. TbpA was found to afford protection against meningococcal challenge when administered as the sole immunogen [PubMed: 11179327].</rdfs:comment>
        <rdfs:label>TbpA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 833; NCBI Protein GI: 8926211; NCBITaxon: 487</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012381 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012381">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015471"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012381</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <obo:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000137"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In chimpanzees (Pan troglodytes), the primates most closely related to humans and that share a similar susceptibility to P. falciparum liver-stage infection, immunization with LSA-3 induced protection against successive heterologous challenges with large numbers of P. falciparum sporozoites [PubMed: 11062538].</rdfs:comment>
        <rdfs:label>LSA-3</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 834; NCBI Gene GI: 812783; NCBI Protein GI: 124801463; NCBI Protein Accession: XP_001349701; NCBITaxon: 36329</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012382 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012382">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010771"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012382</metadata:prefixIRI>
        <obo:BFO_0000051 rdf:resource="http://purl.obolibrary.org/obo/OPL_0000242"/>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>1 of 3 Monkeys vaccinated with EBA-175 was protected from challenge of parasitized erythrocytes [PubMed: 11471569].</rdfs:comment>
        <rdfs:label>eba-175</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 835; NCBI Gene GI: 2654998; NCBI Protein GI: 296004911; NCBI Protein Accession: XP_001349207; NCBITaxon: 36329</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012383 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012383">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010779"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012383</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with rPhpA-79 protein adjuvanted with monophosphoryl lipid A (for subcutaneous immunization) or a mutant cholera toxin, CT-E29H (for intranasal immunization), protected CBA/N mice against death and bacteremia, as well as reduced nasopharyngeal colonization, following intranasal challenge with a heterologous pneumococcal strain [PubMed: 11349048].</rdfs:comment>
        <rdfs:label>phpA-79</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 836; NCBI Protein GI: 13447096; NCBITaxon: 32630</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012384 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012384">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012368"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012384</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with recombinant OspA protein were protected from challenge with Borrelia burgdorferi [PubMed: 8168958].</rdfs:comment>
        <rdfs:label>OspA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 838; NCBI Gene GI: 1194357; NCBI Protein GI: 11496927; NCBI Protein Accession: NP_045688; NCBITaxon: 224326</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012385">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012368"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012385</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with recombinant OspB protein were protected from challenge with Borrelia burgdorferi [PubMed: 8168958].</rdfs:comment>
        <rdfs:label>OspB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 839; NCBI Gene GI: 1194340; NCBI Protein GI: 11496910; NCBI Protein Accession: NP_045689; NCBITaxon: 224326</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012386">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012368"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012386</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with recombinant OspC protein were protected from challenge with Borrelia burgdorferi [PubMed: 8168958].</rdfs:comment>
        <rdfs:label>OspC</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 840; NCBI Gene GI: 1194415; NCBI Protein GI: 11497024; NCBI Protein Accession: NP_047005; NCBITaxon: 224326</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012387 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012387">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012368"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012387</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with recombinant DbpA protein are protected against challenge with Borrelia burgdorferi [PubMed: 11035759].</rdfs:comment>
        <rdfs:label>DbpA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 841; NCBI Gene GI: 8319341; NCBI Protein GI: 256041910; NCBI Protein Accession: YP_003110629; NCBITaxon: 521009</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012388 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012388">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012369"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012388</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In an attempt to generate a subunit vaccine in this experimental disease model, eukaryotic plasmid DNA expression vectors containing genes encoding either the wild-type or modified forms of recombinant listeriolysin O (hly) were generated and used for genetic vaccination of naive mice. Results of these studies indicate that the intramuscular immunization of mice with specifically designed plasmid DNA constructs encoding recombinant forms of listeriolysin O (hly) stimulates peptide-specific CD8+ immune T cells that exhibit in vitro cytotoxic activity. More importantly, such immunization can provide protective immunity against a subsequent challenge with viable L. monocytogenes [PubMed: 10384131].</rdfs:comment>
        <rdfs:label>Hly</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 842; NCBI Gene GI: 987033; NCBI Protein GI: 16802248; NCBI Protein Accession: NP_463733; NCBITaxon: 169963</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012389 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012389">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012355"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012389</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice were immunized with a recombinant fragment of CNA protein, and were then challenged  with the S. aureus clinical isolate strain Phillips. At 14 d after inoculation, mortality in the collagen adhesin-vaccinated group was only 13%, compared with 87% in the control antigen immunized group [PubMed: 9637697].</rdfs:comment>
        <rdfs:label>CNA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 846; NCBI Nucleotide GI: 387879; NCBI Protein GI: 387880; NCBI Protein Accession: AAA20874.1; NCBITaxon: 1280</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012390 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012390">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012355"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012390</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with recombinant ClfA and challenged with S. aureus developed less-severe arthritis than did mice immunized with a control antigen [PubMed: 11740733].</rdfs:comment>
        <rdfs:label>ClfA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 847; NCBI Gene GI: 5330438; NCBI Protein GI: 151220968; NCBI Protein Accession: YP_001331790; NCBITaxon: 426430</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012391 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012391">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012355"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012391</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>An internal region from the transpeptidase domain from the PBP2a (encoded by mecA) was cloned into a mammalian expression vector, to be used as DNA vaccine in a Murine model. After three sets of DNA vaccination, the immune response represented by antibodies against a fragment of PBP2a was evaluated by enzyme linked immunosorbent assay (ELISA), showing a significant antibody response. The antibacterial effect of the DNA vaccine was evaluated by intraperitoneal immunization and challenge with a sublethal dose of MRSA for 7 days in mice. After the challenge, the number of bacteria from kidneys from immunized and non-immunized mice were determined. Kidneys from immunized mice had 1000 times less on bacteria than the positive controls (non-immunized mice) [PubMed: 12744903].</rdfs:comment>
        <rdfs:label>MecA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 848; NCBI Gene GI: 2861157; NCBI Protein GI: 49482291; NCBI Protein Accession: YP_039515; NCBITaxon: 282458</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012392 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012392">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012355"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012392</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice were immunized with fusion proteins encompassing the fibronectin-binding domain of a staphylococcal fibronectin-binding protein (FnBP-A). Vaccination of mice with recombinant FnBP resulted in significant protection against challenge with S. aureus [PubMed: 7975852].</rdfs:comment>
        <rdfs:label>FnbA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 849; NCBI Protein GI: 120457; NCBITaxon: 93061</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012393 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012393">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012356"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012393</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization of mice with recombinant BPS protein by the subcutaneous route produced an efficient antigen-specific response, and immunized animals survived challenge with a lethal dose of a virulent strain [PubMed: 11796614].</rdfs:comment>
        <rdfs:label>BPS</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 850; NCBI Protein GI: 5327234; NCBITaxon: 1311</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012394 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012394">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012357"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012394</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Intranasal immunization of mice with either SfbI alone or coupled to cholera toxin B subunit (CTB) triggered efficient SfbI-specific humoral (mainly IgG) and lung mucosal (14% of total IgA) responses. SfbI-vaccinated animals showed 80% and 90% protection against homologous and heterologous challenge, respectively [PubMed: 10068585].</rdfs:comment>
        <rdfs:label>SfbI</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 851; NCBI Nucleotide GI: 511149; NCBI Protein GI: 511150; NCBI Protein Accession: CAA48133.1; NCBITaxon: 1314</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012395 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012395">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012357"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012395</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice subcutaneously or orally immunized with FBP54 survived significantly longer following the challenge with S. pyogenes than did nonimmunized mice [PubMed: 11159987].</rdfs:comment>
        <rdfs:label>FBP54</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 852; NCBI Nucleotide GI: 496254; NCBITaxon: 1314</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012396 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012396">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012357"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012396</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with FbpA were protected from challenge with group A streptococcus [PubMed: 19254483].</rdfs:comment>
        <rdfs:label>FbaA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 853; NCBI Protein GI: 14915682; NCBITaxon: 1314</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012397 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012397">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012357"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012397</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice were intranasally immunized with diphtheria toxoid (DT) conjugated polypeptides encompassing a conformational-constrained B cell epitope of the M1 protein (J8). Vaccinated mice were challenged 10 days after the last boost by the intranasal route. Animals had 60% protection against challenge [PubMed: 16828529].</rdfs:comment>
        <rdfs:label>Emm1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 854; NCBI Nucleotide GI: 311757; NCBI Protein GI: 311758; NCBI Protein Accession: CAA44062.1; NCBITaxon: 1314</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012398 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012398">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012357"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012398</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with Sib 35 enhanced survival rates in mice challenged with a GAS strain, while exhibiting no toxicity in hosts [PubMed: 15990202].</rdfs:comment>
        <rdfs:label>Sib35</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 855; NCBI Protein GI: 90567992; NCBITaxon: 342023</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012399 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012399">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012358"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012399</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with the recombinant GlpQ significantly protected rabbits from subsequent T. pallidum challenge, altering lesion development at the sites of challenge [PubMed: 9826352].</rdfs:comment>
        <rdfs:label>GlpQ</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 856; NCBI Gene GI: 2611763; NCBI Protein GI: 15639249; NCBI Protein Accession: NP_218698; NCBITaxon: 243276</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012400 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012400">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012358"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012400</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Treponema pallidum-susceptible guinea pigs of strain C4D were immunized with recombinant T. pallidum antigen TmpB. Guinea pigs receiving TmpB antigen demonstrated protection expressed by the development of significantly (P less than 0.01) smaller, atypical lesions of significantly (P less than 0.01) shorter duration and devoid of or containing fewer T. pallidum organisms than lesions in the remaining immunized and control animals [PubMed: 1937794].</rdfs:comment>
        <rdfs:label>TmpB</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 857; NCBI Gene GI: 2611387; NCBI Protein GI: 15639756; NCBI Protein Accession: NP_219206; NCBITaxon: 243276</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012401 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012401">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012358"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012401</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with recombinant Tp92 partially protected rabbits from subsequent T. pallidum challenge [PubMed: 10762571].</rdfs:comment>
        <rdfs:label>Tp92</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 858; NCBI Protein GI: 159158965; NCBITaxon: 243276</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012402 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012402">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012356"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012402</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Immunization with the recombinant Sip protein efficiently protected CD-1 mice against deadly challenges with six GBS strains of serotypes Ia/c, Ib, II/R, III, V, and VI [PubMed: 10992461].</rdfs:comment>
        <rdfs:label>Sip</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 859; NCBI Gene GI: 3685788; NCBI Protein GI: 76788047; NCBI Protein Accession: YP_328758; NCBITaxon: 205921</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012403 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012403">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012356"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012403</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination of mice with the Rib protein protected against two strains of capsular type III and two strains of type II, and vaccination with the alpha protein protected against one strain of type II and one strain of type Ib [PubMed: 8751893].</rdfs:comment>
        <rdfs:label>Rib</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 860; NCBI Protein GI: 1620648; NCBITaxon: 1311</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012404 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012404">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0012369"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012404</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mice immunized with p60 encapsulated in  liposomes launched a strong CTL response and were protected against a subsequent challenge with L. monocytogenes [PubMed: 18433404].</rdfs:comment>
        <rdfs:label>p60</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 862; NCBI Protein GI: 215422507; NCBITaxon: 1639</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012405 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012405">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012405</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Mouse antiserum directed against the recombinant NucA protein was reactive on Western immunoblots and whole-cell ELISA with all H. influenzae strains tested including Eagan and was bactericidal for two heterologous strains tested. The antiserum also resulted in a log reduction in bacteremia, in an infant-rat protection study with H. influenzae type b as the challenge strain [PubMed: 10768940].</rdfs:comment>
        <rdfs:label>NucA</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 863; NCBI Protein GI: 4929317; NCBITaxon: 727</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012406 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012406">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010772"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012406</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>When chinchillas were immunized with recombinant P1 (rP1) obtained from one of these isolates (BCH-3), all animals developed antibodies specific for rP1. Immunized animals were protected against disease when challenged with BCH-3, but not with an ompP1 mutant of BCH-3 or a strain (BCH-2) possessing a heterologous P1 (91% identity). We conclude that (i) while P1 induces protection against NTHI-mediated otitis media, development of a polyvalent vaccine reflecting the variability of P1 would be necessary to construct an efficacious vaccine [PubMed: 10899849].</rdfs:comment>
        <rdfs:label>OmpP1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 864; NCBI Protein GI: 9716645; NCBITaxon: 727</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012407 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012407">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012407</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>Vaccination with the recombinant PstS-1 antigen and cholera toxin significantly protected against the challenge given 10 days later, but only marginally after 12 weeks [PubMed: 10869767].</rdfs:comment>
        <rdfs:label>PstS1</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 865; NCBI Gene GI: 885724; NCBI Protein GI: 57116801; NCBI Protein Accession: YP_177770; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012408 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012408">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012408</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>In an ex vivo transfection approach with a retroviral vector a single antigen (hsp70) could evoke strong protection in mice [PubMed: 9234527].</rdfs:comment>
        <rdfs:label>DnaK from Mycobacterium tuberculosis</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 866; NCBI Gene GI: 885946; NCBI Protein GI: 15607491; NCBI Protein Accession: NP_214864; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0012409 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0012409">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0001232"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010770"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0012409</metadata:prefixIRI>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000457"/>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:comment>A single DNA vaccine encoding the MPT-83 tuberculosis antigens evoked partial protection against an aerogenic challenge with M. tuberculosis Erdman in the mouse model of pulmonary tuberculosis [PubMed: 10715531].</rdfs:comment>
        <rdfs:label>MPT83</rdfs:label>
        <rdfs:seeAlso>Protegen ID: 867; NCBI Gene GI: 887155; NCBI Protein GI: 15610010; NCBI Protein Accession: NP_217389; NCBITaxon: 83332</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015001">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003451"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018834"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015001</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/803365</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>803365</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0003560>hepatitis A vaccine (inactivated) strain HM175 720 UNT/ML / hepatitis B surface antigen vaccine 0.02 MG/ML [Twinrix]</obo:VO_0003560>
        <obo:VO_0010151>19131619</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Twinrix]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015006"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018834"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015003</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/803371</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
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    <!-- http://purl.obolibrary.org/obo/VO_0015004 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015005 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015006 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015008 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015009 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015011 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015016 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015017 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015020 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015022 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015023 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015024 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015025 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015026 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015027 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015028 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015029 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015030 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015031 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015032 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015038 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015039 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015040 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015041 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015042 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015044 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015045 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0015046 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0015047 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015048 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015049 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015050 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015053 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015054 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015060 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015061 -->

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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015071</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.bioontology.org/ontology/RXNORM/797634</obo:IAO_0000119>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>797634</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <obo:VO_0003560>Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>528298</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015072 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015072">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015072</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>injectable suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015073">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>injectable solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015074 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015074">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118>injection</obo:IAO_0000118>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>injection form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015075">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015061"/>
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>intramuscular solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015076">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015076</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>drug package</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015077 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015077">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015077</metadata:prefixIRI>
        <obo:IAO_0000115>An information content entity that specifies a family of drug products containing a specific active ingredient.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.nlm.nih.gov/research/umls/rxnorm/docs/appendix5.html</obo:IAO_0000119>
        <oboInOwl:inSubset>information content entity</oboInOwl:inSubset>
        <rdfs:label>drug brand name</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015080 -->

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        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015080</metadata:prefixIRI>
        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone 2015-2016 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015081 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015062"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone 2015-2016 Injectable Product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015084 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015084">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000919"/>
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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>1657128</obo:VO_0003198>
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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Influenza A virus (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015085 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
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        <obo:VO_0003198>1657131</obo:VO_0003198>
        <obo:VO_0003560>influenza A virus (H3N2) antigen</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015086 -->

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        <obo:IAO_0000117>Khadeejah Khan</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza B virus antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015087 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0010151>41409674</obo:VO_0010151>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 100 UNT/ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015088 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015093 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015094 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015095 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015096 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015098 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015099 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015100 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015101 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015102 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015104 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015105 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015106 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015107 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015108 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015109 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015110 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015111 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015112 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015113 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015114 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015115 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015116 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015117 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015118 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0015119 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015120 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015121 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015122 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015123 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015124 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015125 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015132 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015133 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015134 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015135 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015136 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015137 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015138 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015139 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015140 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015141 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015142 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015143 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015144 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015145 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015146 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015152 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015153 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015154 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015155 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015156 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015157 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015158 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015159 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015160 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015162 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015163 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015164 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015165 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015167 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015168 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015172 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015179 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015180 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015181 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015182 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015184 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015185 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015186 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015187 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015188 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015190 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015191 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015192 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015193 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015194 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003560>1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injectable Suspension [Havrix] Box of 1 by Glaxosmithkline</obo:VO_0003560>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015195 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015196 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
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        <rdfs:label>obsolete 1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015197 -->

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        <obo:VO_0010151>41333720</obo:VO_0010151>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015198 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015199 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015200 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015201 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015202 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015203 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015204 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015205 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015206 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015207 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015208 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015213 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015214 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015215 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015216 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015218 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015219 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0015220 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015221 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015222 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015223 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015224 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015225 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015226 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015227 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015228 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0015229 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015230 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015231 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015232 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015237 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015238 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015239 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015240 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015241 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015243 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015247 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015248 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015249 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015250 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015252 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015253 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015254 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015255 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015256 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015261 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015262 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015263 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015264 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015265 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015266 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015268 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015269 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015270 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015272 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015273 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015275 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015276 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015277 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015278 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015281 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015295 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015296 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015297 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015300 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015301 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015302 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015303 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015314 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015315 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015316 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015317 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015318 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015319 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015320 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015321 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015322 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015323 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015324 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015325 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015326 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015327 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015329 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015330 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015332 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015334 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015335 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015336 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015337 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015338 -->

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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML [Vivaxim]</obo:VO_0003560>
        <obo:VO_0010151>43258581</obo:VO_0010151>
        <obo:VO_0010152>OMOP558178</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML [Vivaxim]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015339 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015339">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0015337"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010438"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010451"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015337"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015339</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML Injection</obo:VO_0003560>
        <obo:VO_0010151>43264016</obo:VO_0010151>
        <obo:VO_0010152>OMOP558179</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML Injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015340 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015340">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0015339"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015345"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015338"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015339"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015345"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015340</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML Injection [Vivaxim]</obo:VO_0003560>
        <obo:VO_0010151>43285829</obo:VO_0010151>
        <obo:VO_0010152>OMOP558180</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis A Virus 160 UNT/ML / Salmonella Typhi Inactivated Antigen 0.025 MG/ML Injection [Vivaxim]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015471 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015471">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010771"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015471</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium falciparum protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015472 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015472">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010771"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015472</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium knowlesi protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015473 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015473">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010771"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015473</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium vivax protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015474 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015474">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010771"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015474</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium yoelii protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015475 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015475">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010771"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015475</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium berghei protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015476 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015476">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010771"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015476</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Plasmodium chabaudi protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015478 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015478">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010755"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015478</metadata:prefixIRI>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Leishmania protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015483 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015483">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010829"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015483</metadata:prefixIRI>
        <obo:IAO_0000117>Anthony Huffman</obo:IAO_0000117>
        <oboInOwl:inSubset>protein</oboInOwl:inSubset>
        <rdfs:label>Giardia lamblia protein</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015484 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015484">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003960"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015484</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003560>Neisseria meningitidis Group B Membrane vesicles External Omv</obo:VO_0003560>
        <obo:VO_0010151>36878723</obo:VO_0010151>
        <obo:VO_0010152>OMOP990054</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis Group B Membrane vesicles External Omv</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015485 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015485">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015489"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011093"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015485</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011093"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>830258</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003560>0.5 ML hepatitis B surface antigen vaccine 0.005 MG/ML Prefilled Syringe</obo:VO_0003560>
        <obo:VO_0005279>0.5 ML hepatitis B surface antigen vaccine 0.0005 % Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>19133383</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015486 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0015486">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015499"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0011093"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0015486</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011093"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_2043"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2050057</obo:VO_0003198>
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        <obo:VO_0005279>hepatitis B surface antigen vaccine 0.04 MG/ML per 0.5 ML Prefilled Syringe</obo:VO_0005279>
        <obo:VO_0010151>35201908</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0015487 -->

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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0002180 rdf:resource="http://purl.obolibrary.org/obo/VO_0011093"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015488 -->

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        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis Recombinant Fusion Protein Fhbp Group B</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0015489 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0015490 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015491 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015492 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015493 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015500 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015501 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015502 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015503 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015504 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015505 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015506 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015507 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015508 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015509 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015510 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015511 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015512 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015513 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0015514 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0015515 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015516 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015517 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015518 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015519 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015520 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015521 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015522 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015523 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015524 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015525 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015526 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015527 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015528 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015529 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015530 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015531 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015533 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015537 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015538 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015539 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015540 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015541 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015542 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015543 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015544 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015545 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015546 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015547 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015548 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015549 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015550 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015551 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015552 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015553 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015554 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015555 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015558 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015559 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015560 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015561 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015562 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015563 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015565 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015569 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015570 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015572 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015575 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015579 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015580 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015582 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015584 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015585 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015586 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015587 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015588 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015589 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015590 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015591 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015592 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015593 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015594 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015595 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015596 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015597 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015598 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015600 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015601 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015602 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015603 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015604 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015605 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015608 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015611 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015612 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015613 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015614 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015615 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015616 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015617 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015618 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015619 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015620 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015621 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015622 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015623 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015624 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015626 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015627 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015628 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015629 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015631 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015632 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015633 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015634 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015635 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015636 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015637 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015638 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015639 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015640 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015641 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015642 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015643 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015644 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015646 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015647 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015648 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015649 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015650 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015651 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015669 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015670 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015671 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015672 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015676 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015677 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015678 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015680 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015682 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015683 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015701 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015710 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015711 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015712 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015713 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015714 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015715 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015716 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015717 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015718 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015719 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015720 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015721 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015722 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015723 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015724 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015729 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015730 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015731 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015733 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015734 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015735 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015736 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015737 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015738 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015740 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015749 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015750 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015755 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015756 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015765 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015766 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015767 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015800 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015801 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015802 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015812 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015815 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015816 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015817 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015818 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015819 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015820 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015821 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015822 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015823 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015824 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015825 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015826 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015827 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015828 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015829 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015830 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015831 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015832 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015833 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015834 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015835 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015836 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015837 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015838 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015839 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015840 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015841 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015842 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015843 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015845 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015847 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015849 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015850 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015851 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015852 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015853 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015854 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015855 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015856 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015857 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015858 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015859 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015860 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015865 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015875 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015876 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015877 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015878 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015899 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015900 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015901 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015904 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015905 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015909 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015910 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015911 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015913 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015914 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015915 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015916 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015917 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015918 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015919 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015920 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015921 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015922 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015923 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015924 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015925 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015927 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015929 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015931 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015932 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015980 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015981 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015982 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015983 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015984 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015987 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015996 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0015998 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016000 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016001 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016002 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016003 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016004 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016005 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016006 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016007 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016008 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016010 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016011 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016012 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016013 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016021 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016022 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016023 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016024 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016031 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016032 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016034 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016037 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016038 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016067 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016080 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016083 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016089 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016090 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016091 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016092 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016093 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016094 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016095 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016096 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016097 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016098 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016099 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016100 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016101 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016102 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016103 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016104 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016106 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016107 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016108 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016109 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016110 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016111 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016112 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016113 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016114 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016115 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016116 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016117 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016118 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016119 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016120 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016121 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016122 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016123 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016124 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016125 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016126 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016127 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016128 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016129 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016130 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016131 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016132 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016133 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016134 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016135 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016136 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016137 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016138 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016139 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016140 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016141 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016142 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016143 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016144 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016145 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016146 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016147 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016148 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016151 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016154 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016155 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016156 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016157 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016158 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016159 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016160 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016161 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016162 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016163 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016164 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016166 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016167 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016168 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016169 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016170 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016179 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016180 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016183 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016184 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016185 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016186 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016187 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016188 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016189 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016190 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016191 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016193 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016194 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016195 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016196 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016197 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016198 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016199 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016200 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016201 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016202 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016203 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016204 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016205 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016206 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016207 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016208 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016209 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016210 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016211 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016212 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016213 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016214 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016215 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016216 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016217 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016218 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016219 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016220 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016221 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016222 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016223 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016224 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016225 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016226 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016227 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016228 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016229 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016230 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016231 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016232 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016233 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016234 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016235 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016236 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016237 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016238 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016239 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016240 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016241 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016244 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016247 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016248 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016249 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016250 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016251 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016254 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016257 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016258 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016259 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016260 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016261 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016262 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016265 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016266 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016267 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016268 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016273 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016281 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016282 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016287 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016288 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016296 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016297 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016298 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016299 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016300 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016301 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016302 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016303 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016304 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016305 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016306 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016307 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016308 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016309 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016310 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016311 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016312 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016313 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016314 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016315 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016316 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016317 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016318 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016319 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016320 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016321 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016322 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016323 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016325 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016326 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016327 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016328 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016329 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016330 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016331 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016332 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016333 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016334 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016335 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016336 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016337 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016338 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016339 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016341 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016342 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016343 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016344 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016345 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016346 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016347 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016348 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016349 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016350 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016351 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016352 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016353 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016354 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016363 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016364 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016365 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016367 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016375 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016396 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016397 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016398 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016399 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016400 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016401 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016402 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016416 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016417 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016418 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016419 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016420 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016421 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016422 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016423 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016424 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016425 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016426 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016432 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016433 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016434 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016435 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016436 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016439 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016455 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016456 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016475 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016477 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016478 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016479 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016480 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016482 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016483 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016487 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016488 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016490 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016491 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016492 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016493 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016494 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016495 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016507 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016508 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016509 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016510 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016514 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016515 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016518 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016519 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016520 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016521 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016522 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016523 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016524 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016525 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016526 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016534 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016535 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016536 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016537 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016540 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016542 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016547 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016550 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016551 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016552 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016554 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016556 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016572 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016573 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016574 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016575 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016576 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016586 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016587 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016611 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016618 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016619 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016620 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016621 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016623 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016624 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016630 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016631 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016632 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016638 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016639 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016642 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016643 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016644 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016645 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016667 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016668 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016669 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016672 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016673 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016674 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016675 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016676 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016685 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016688 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016689 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016690 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016691 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016711 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016714 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016715 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016716 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016717 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016719 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016720 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016721 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016722 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016723 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016725 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016726 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016728 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016729 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016730 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016731 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016733 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016734 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016735 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016736 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016791 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016792 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016794 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016818 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016819 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016820 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016822 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016823 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016824 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016828 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016847 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016848 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016849 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016850 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016852 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016853 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016854 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016872 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016873 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016874 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016875 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016921 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016922 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016923 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016925 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016929 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016957 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016987 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016988 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016989 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016990 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0016999 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017003 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017021 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017022 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017042 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017044 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017054 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017056 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017057 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017101 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017102 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017112 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017113 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017114 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017123 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017128 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017129 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017130 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017131 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017162 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017179 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017180 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017181 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017182 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017185 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017186 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017196 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017198 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017199 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017200 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017201 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017206 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017210 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017262 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017332 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017360 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017361 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017376 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017377 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017378 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017379 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017381 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017388 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017392 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017393 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017394 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017395 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017396 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017413 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017414 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017415 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017416 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017417 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017437 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017438 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017451 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017452 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017454 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017480 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017481 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017484 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017489 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017490 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017491 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017499 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017503 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017504 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017505 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017512 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017513 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017514 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017515 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017517 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017518 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017519 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017522 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017523 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017524 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017525 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017526 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017528 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017529 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017534 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017537 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017539 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017543 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017544 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017548 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017577 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017590 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017591 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017592 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017593 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017611 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017614 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017615 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017616 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017618 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017619 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017620 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017621 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017622 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017632 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017638 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017639 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017649 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017652 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017653 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017654 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017655 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017656 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017657 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017660 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017663 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017664 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017665 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017666 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017667 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017668 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017670 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017672 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017673 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017674 -->

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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0017675 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0017676 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0017677 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <rdfs:label>hepatitis B virus subtype ADW2 HBsAg surface protein antigen</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0017678 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017679 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017680 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017681 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017714 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017715 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017716 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017717 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017718 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017719 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017720 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017721 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017722 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017723 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017724 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017725 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017726 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017727 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017728 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017729 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017730 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017731 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017740 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017746 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017748 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017772 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017773 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017774 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017775 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017776 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017777 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017778 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017779 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017785 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017786 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017787 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017788 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017789 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017790 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017797 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017798 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017799 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017800 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017802 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017806 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017807 -->

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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0017811</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus antigen, Hong Kong 330-2001 / meningococcal group C polysaccharide</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017812 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0017812">
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        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0017812</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017813 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0017813">
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0017813</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Meningococcal Polysaccharide Vaccine, Groups A &amp; C</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017814 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0017814">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000053"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000195"/>
        <rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0017814</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000625"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus B Conjugate Vaccine / meningococcal group C polysaccharide</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017815 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0017815">
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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y / tetanus toxoid vaccine, inactivated</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017816 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0017816">
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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group C polysaccharide / tetanus toxoid vaccine, inactivated</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017817 -->

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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017818 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0017818</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <rdfs:label>Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injectable Solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017819 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017820 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017821 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017822 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017825 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017826 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017827 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017828 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017829 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017830 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017831 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017832 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017833 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017834 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017835 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017836 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017837 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017838 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017839 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017840 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017841 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017842 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017843 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017844 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017845 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017846 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080176"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_487"/>
        <obo:VO_0003560>meningococcal group A polysaccharide 0.008 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>44026807</obo:VO_0010151>
        <obo:VO_0010152>OMOP1021438</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group A polysaccharide 0.008 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017852 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0003560>meningococcal group A polysaccharide 0.5 MG</obo:VO_0003560>
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        <obo:VO_0010152>OMOP1047516</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group A polysaccharide 0.5 MG</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017853 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0017853</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003560>meningococcal group A polysaccharide 2.5 MG</obo:VO_0003560>
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        <obo:VO_0010152>OMOP1021439</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group A polysaccharide 2.5 MG</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017854 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0017854">
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003560>meningococcal group B vaccine 0.3 MG/ML</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group B vaccine 0.3 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017855 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017856 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>meningococcal group C polysaccharide 0.5 MG</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017857 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017858 -->

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        <rdfs:label>MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.008 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0017859 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017860 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017861 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017862 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017863 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017864 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017865 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017866 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017867 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017870 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017877 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017881 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017884 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017885 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017887 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017889 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017890 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017891 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017893 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017909 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017910 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017911 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017912 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017913 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017914 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017915 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017916 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017917 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017918 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017919 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017920 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017921 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017922 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017923 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017924 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017925 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017926 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017927 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017928 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017929 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017930 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017931 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017932 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017933 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017934 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017935 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017936 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017937 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017938 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017939 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017940 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017957 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017958 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017959 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017960 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017979 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017989 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017990 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017991 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017992 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017993 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017994 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0017996 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018008 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018009 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018010 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018011 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018012 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018013 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018014 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0018015 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018016 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018017 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018018 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018019 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018020 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018021 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018022 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018023 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018024 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018025 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018026 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018027 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018028 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018029 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018030 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018031 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018032 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018033 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018034 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018035 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018037 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018038 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018039 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018040 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018043 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018044 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018045 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018046 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018047 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018048 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018049 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018052 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018093 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018094 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018095 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018096 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018098 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018099 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018100 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018109 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018110 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018111 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018121 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018126 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018132 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018133 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018134 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018140 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018141 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018142 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018144 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018159 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018160 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018161 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018180 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018181 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018182 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018183 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018185 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018193 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018194 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018195 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018197 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018198 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018199 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018200 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018201 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018202 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018204 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018205 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018206 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018207 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018208 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018210 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018212 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018216 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018217 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018219 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018227 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018228 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018229 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018230 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018232 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018242 -->

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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0018243 -->

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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0018244 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018245 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018246 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018247 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018252 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018253 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018254 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018255 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018256 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018257 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018258 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018259 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018260 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018261 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018262 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018263 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018264 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018265 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018266 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018267 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018278 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018293 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018294 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018295 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018296 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018298 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018299 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018300 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018302 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018313 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018316 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018317 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018318 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018319 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018320 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018323 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018326 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018328 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018338 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018339 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018340 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018341 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018380 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018386 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018390 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018391 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018392 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018393 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018394 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe [Pnu-Imune]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0018396 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 1 vaccine Prefilled Syringe [Prevnar]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0018397 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0018398 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0018399 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018400 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018401 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018402 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018403 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0003560>pneumococcal capsular polysaccharide type 18C vaccine 0.004 MG</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 18C vaccine 0.004 MG</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018404 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <rdfs:label>pneumococcal capsular polysaccharide type 18C vaccine 0.006 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0018405 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>pneumococcal capsular polysaccharide type 19F vaccine 0.004 MG</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0018406 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <rdfs:label>pneumococcal capsular polysaccharide type 19F vaccine 0.006 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018407 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018408 -->

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        <rdfs:label>pneumococcal capsular polysaccharide type 23F vaccine 0.002 MG/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0018409 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018410 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018411 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018412 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018413 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018414 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018415 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018416 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018417 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018418 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018419 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018425 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018426 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018427 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018428 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018431 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018433 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018434 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018435 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018513 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018514 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018515 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018516 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018518 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018525 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018526 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018527 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018528 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018529 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018530 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018531 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018532 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018533 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018534 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018535 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018536 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018539 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018548 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018549 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018550 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018551 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018560 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018561 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018562 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018566 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018567 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018569 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018570 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018571 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018572 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018573 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018582 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018586 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018587 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018588 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018589 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018590 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018591 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018592 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018593 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018594 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018595 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018596 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018597 -->

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        <obo:VO_0010151>44039976</obo:VO_0010151>
        <obo:VO_0010152>OMOP1034607</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 2210000 UNT</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018598 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018598</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10912"/>
        <obo:VO_0003560>Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 770000 PFU/ML</obo:VO_0003560>
        <obo:VO_0010151>43296580</obo:VO_0010151>
        <obo:VO_0010152>OMOP558085</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 770000 PFU/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018599 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018599">
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018599</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0003560>Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 772000 PFU/ML</obo:VO_0003560>
        <obo:VO_0010151>588735</obo:VO_0010151>
        <obo:VO_0010152>OMOP3137149</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 772000 PFU/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018600 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018600">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004823"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018600</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003560>Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 2840000 UNT</obo:VO_0003560>
        <obo:VO_0010151>44039975</obo:VO_0010151>
        <obo:VO_0010152>OMOP1034606</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 2840000 UNT</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018601 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018601">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004823"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018601</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003560>Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 980000 PFU/ML</obo:VO_0003560>
        <obo:VO_0010151>43275027</obo:VO_0010151>
        <obo:VO_0010152>OMOP558092</obo:VO_0010152>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 980000 PFU/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018602 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018602">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0004824"/>
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003560>Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 2220000 UNT</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 2220000 UNT</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018603 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018603">
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003560>Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 770000 PFU/ML</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 770000 PFU/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018604 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 772000 PFU/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018605 -->

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        <obo:VO_0003560>Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 2040000 UNT</obo:VO_0003560>
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        <obo:VO_0010152>OMOP1021630</obo:VO_0010152>
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        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 2040000 UNT</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0018606 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0018607 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 700000 PFU/ML</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0018608 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003560>Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 2290000 UNT</obo:VO_0003560>
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        <rdfs:label>Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 2290000 UNT</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0018609 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018610 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018611 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018612 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018613 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018614 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018615 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018616 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018617 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018618 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018619 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018626 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018630 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018631 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018632 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018633 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018634 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018636 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018637 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018638 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018639 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018642 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018643 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018644 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018645 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018646 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018647 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018648 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018649 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018650 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018651 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018652 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018653 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018672 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018673 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018674 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018675 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018677 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018678 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018679 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018680 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018681 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018682 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018684 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018685 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018688 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018689 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018690 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018695 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018698 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018699 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018700 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018701 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018702 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018703 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018704 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018705 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018706 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018709 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018710 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018711 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018712 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018713 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018714 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018715 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018716 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018717 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018718 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018719 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018720 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018721 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018732 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018733 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018734 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018749 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018750 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018752 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018754 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018755 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018756 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018757 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018758 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018759 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018760 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018761 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018764 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018766 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018772 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018773 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018777 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018778 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018779 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018780 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018781 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018782 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018783 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018784 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018785 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018789 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018792 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018793 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018794 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018795 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018796 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018797 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018799 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0018800 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018801 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018802 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018803 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018804 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018805 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018806 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018806</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11260"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1658029</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11292"/>
        <obo:VO_0003560>rabies virus vaccine flury-lep strain Injection</obo:VO_0003560>
        <obo:VO_0010151>46275153</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>rabies virus vaccine flury-lep strain Injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018807 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018807</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003198>762819</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11041"/>
        <obo:VO_0003560>rubella virus vaccine live (Wistar RA 27-3 strain) Injectable Solution</obo:VO_0003560>
        <obo:VO_0010151>40148731</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) Injectable Solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018808 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003560>yellow fever virus strain 17D-204 live antigen Injectable Suspension</obo:VO_0003560>
        <obo:VO_0010151>42800063</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>yellow fever virus strain 17D-204 live antigen Injectable Suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018809 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018809">
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_9682"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Yellow-Fever Virus Vaccine, 17D-204 strain Injectable Suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018843 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>oral</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018844 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018844">
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <rdfs:label>oral suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018845 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018845">
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>powder for oral suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018846 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>oral capsule</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018847 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018847">
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>oral tablet</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018848 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018848">
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0018849 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003198>1804260</obo:VO_0003198>
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    <!-- http://purl.obolibrary.org/obo/VO_0018850 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <rdfs:label>influenza A virus A/Indonesia/05/2005 (H5N1) antigen 0.0075 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018851 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018852 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018853 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018854 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018855 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018856 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018857 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018858 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018859 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018860 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018861 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018862 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018863 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018864 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018865 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018866 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018867 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018868 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018869 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018870 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018871 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018872 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018873 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018874 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018875 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018876 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018877 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018878 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018879 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018880 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018881 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018882 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018883 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018884 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018885 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018886 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018887 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018888 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018889 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018890 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018891 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018892 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018893 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018894 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018895 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018896 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018897 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018898 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018899 -->

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        <obo:VO_0003198>2564394</obo:VO_0003198>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <obo:VO_0003560>influenza A virus A/Tasmania/503/2020 (H3N2) antigen 158000000 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>701447</obo:VO_0010151>
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    <!-- http://purl.obolibrary.org/obo/VO_0018900 -->

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        <obo:VO_0003560>influenza A virus A/Victoria/1/2020 (H1N1) antigen 158000000 UNT/ML</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0018901 -->

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        <obo:VO_0010151>1758559</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0018902 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018903 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018904 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018905 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018906 -->

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        <obo:VO_0003198>2605098</obo:VO_0003198>
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    <!-- http://purl.obolibrary.org/obo/VO_0018907 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018908 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018909 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018910 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018911 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018912 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0018913 -->

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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2607742</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_119210"/>
        <obo:VO_0003560>influenza A virus A/Norway/16606/2021 (H3N2) antigen 158000000 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>1525409</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Norway/16606/2021 (H3N2) antigen 158000000 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018914 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018914">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003519"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018914</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2607743</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>influenza B virus B/Austria/1359417/2021 antigen 158000000 UNT/ML</obo:VO_0003560>
        <obo:VO_0010151>1525410</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Austria/1359417/2021 antigen 158000000 UNT/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018915 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018915">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003498"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018915</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2630222</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.0857 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>1301743</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.0857 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018916 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018916">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000362"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000455"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003498"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010415"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018916</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2630656</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_114727"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML</obo:VO_0003560>
        <obo:VO_0010151>1301766</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Sydney/5/2021 (H1N1) antigen 0.03 MG/ML</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018917 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018917">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018917</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Brisbane/02/2018 (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018918 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018918">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018918</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Darwin/6/2021 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018919 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018919">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018919</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Darwin/9/2021 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018920 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018920">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018920</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Guangdong-Maonan/SWL1536/2019 (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018921 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018921">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018921</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Hong Kong/2671/2019 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018922 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018922">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018922</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Kansas/14/2017 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018923 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018923">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018923</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Sydney/5/2021 (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018924 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018924">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015085"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018924</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Tasmania/503/2020 (H3N2) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018925 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018925">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015084"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018925</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus A/Victoria/2570/2019 (H1N1) antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018926 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018926">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015086"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018926</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Austria/1359417/2021 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018927 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018927">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015086"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018927</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Michigan/01/2021 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018928 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018928">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015086"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018928</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza B virus B/Washington/02/2019 antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018929 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0018929">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000919"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0018929</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xumeng Zhang</obo:IAO_0000117>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>yellow fever virus strain 17D-204 live antigen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019097">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015061"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019097</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>oral product</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019098 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019098">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015061"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019098</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>pill</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019099">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0018846"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019099</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>delayed release oral capsule</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015061"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019100</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <oboInOwl:inSubset>material entity</oboInOwl:inSubset>
        <rdfs:label>nasal spray</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019101">
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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0019102 -->

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        <rdfs:label>delayed release oral tablet</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0019103 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019104 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019105 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019106 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019107 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019116 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019117 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019118 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019119 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019120 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019121 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019122 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019123 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019124 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019125 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019126 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019127 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019128 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019129 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019133 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019134 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019135 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019136 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019137 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019138 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019165 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019169 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019173 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019174 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019175 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019176 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019177 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019178 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019179 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019180 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019181 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019182 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019183 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019184 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019185 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019186 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019187 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019188 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019189 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019190 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019191 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019192 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019193 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019194 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019195 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019196 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019197 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019198 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019199 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019200 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019201 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019202 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019203 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019204 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019205 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019206 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019207 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019208 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019209 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019210 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019211 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019212 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019213 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019216 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019217 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019218 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019220 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019221 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019222 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019223 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019224 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019225 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019226 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019227 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019228 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019229 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019230 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019231 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019232 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019233 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019234 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019235 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019236 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019237 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019238 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019239 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019240 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019241 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019242 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019243 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019244 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019245 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019246 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019247 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019248 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019249 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019250 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019251 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019252 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019253 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019254 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019255 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019256 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019257 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019258 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019259 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019260 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019261 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019262 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019263 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019264 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019265 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019266 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019268 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019269 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019270 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019271 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019272 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019273 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019275 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019278 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019299 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019300 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019302 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019308 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019310 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019311 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019315 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019316 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019317 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019318 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019320 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019349 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019350 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019351 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019352 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019353 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019354 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019355 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019356 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019357 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019358 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019360 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019361 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019362 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019363 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019364 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019365 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019366 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019367 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019368 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019370 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019371 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019372 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019373 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019403 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019441 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019442 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019443 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019444 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019445 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019457 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019470 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019474 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019475 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019476 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019477 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019493 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019497 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019498 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019499 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019500 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019501</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000194"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010008"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1658062</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0003560>hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Injection [Havrix]</obo:VO_0003560>
        <obo:VO_0005279>Havrix 1440 UNT/ML Injection</obo:VO_0005279>
        <obo:VO_0010151>46275173</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Injection [Havrix]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019502 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019502">
        <owl:equivalentClass>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0003431"/>
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                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
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                </owl:intersectionOf>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003431"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_12549"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019502</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003198>1359766</obo:VO_0003198>
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        <obo:VO_0003560>hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Prefilled Syringe</obo:VO_0003560>
        <obo:VO_0010151>42902653</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019503 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019503">
        <owl:equivalentClass>
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                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0015344"/>
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        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003827"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015279"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0019502"/>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019503</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003198>1360146</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_12092"/>
        <obo:VO_0003560>hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Prefilled Syringe [Havrix]</obo:VO_0003560>
        <obo:VO_0010151>42903033</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis A vaccine (inactivated) strain HM175 1440 UNT/ML Prefilled Syringe [Havrix]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019504 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019504">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003434"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis A vaccine (inactivated) strain HM175 720 UNT/ML Injectable Suspension</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019505 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019505">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019505</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0015315"/>
        <rdfs:label>obsolete hepatitis A vaccine (inactivated) strain HM175 Injectable Suspension</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019506 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019506">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0018869"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis A virus strain CR 326F antigen, inactivated 50 UNT/ML Injection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019507 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019507</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
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    <!-- http://purl.obolibrary.org/obo/VO_0019510 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019513 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019514 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019515 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019516 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019517 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019518 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019520 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019521 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019522 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019523 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019524 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019525 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019526 -->

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        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019526</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>1360035</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10407"/>
        <obo:VO_0003560>hepatitis B surface antigen vaccine 0.01 MG/ML Prefilled Syringe [Recombivax]</obo:VO_0003560>
        <obo:VO_0010151>42902922</obo:VO_0010151>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B surface antigen vaccine 0.01 MG/ML Prefilled Syringe [Recombivax]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019527 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019527">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003256"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019527</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003198>798453</obo:VO_0003198>
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        <obo:VO_0003560>hepatitis B surface antigen vaccine 0.02 MG/ML [HB-VAX]</obo:VO_0003560>
        <obo:VO_0010151>19030113</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B surface antigen vaccine 0.02 MG/ML [HB-VAX]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019528 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019528">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015493"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019528</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003198>798455</obo:VO_0003198>
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        <obo:VO_0003560>hepatitis B surface antigen vaccine 0.02 MG/ML Injectable Suspension [HB-VAX]</obo:VO_0003560>
        <obo:VO_0005279>HB-VAX 0.02 MG/ML Injectable Suspension</obo:VO_0005279>
        <obo:VO_0010151>528354</obo:VO_0010151>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B surface antigen vaccine 0.02 MG/ML Injectable Suspension [HB-VAX]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019529 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019529">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019529</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0003230"/>
        <rdfs:label>obsolete hepatitis B surface antigen vaccine 0.04 MG/ML</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019530 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019530">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003230"/>
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0010151>19133387</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B surface antigen vaccine 0.04 MG/ML [Recombivax]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019531 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019531">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003152"/>
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        </rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019531</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0005279>Heplisav-B 0.04 MG/ML Injection</obo:VO_0005279>
        <obo:VO_0010151>793521</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B surface antigen vaccine 0.04 MG/ML Injection [Heplisav-B]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019532 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019532">
        <owl:equivalentClass>
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                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0015498"/>
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                </owl:intersectionOf>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0015498"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0019532</metadata:prefixIRI>
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        <obo:VO_0003198>1657686</obo:VO_0003198>
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        <obo:VO_0003560>hepatitis B surface antigen vaccine 0.04 MG/ML Injection [Recombivax]</obo:VO_0003560>
        <obo:VO_0005279>Recombivax 0.04 MG/ML Injection</obo:VO_0005279>
        <obo:VO_0010151>46276311</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>hepatitis B surface antigen vaccine 0.04 MG/ML Injection [Recombivax]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019533 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0019533">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003152"/>
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    <!-- http://purl.obolibrary.org/obo/VO_0019534 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019535 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019536 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019537 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019539 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019540 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019542 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019545 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019546 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019547 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019548 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019549 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019550 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019551 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019552 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019553 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019554 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019555 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019556 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019557 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019558 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019559 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019560 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019561 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019562 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019563 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019564 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019565 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019566 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019567 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019568 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019569 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019570 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019571 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019572 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019573 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019574 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019575 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019576 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019577 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019583 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019585 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019586 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019588 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019589 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019590 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019591 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019592 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019593 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019594 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019595 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019596 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019597 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019598 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019599 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019600 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019601 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019602 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019603 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019604 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019605 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019606 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019607 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019608 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019609 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019610 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019611 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019612 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019613 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019614 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019615 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019616 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019617 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019618 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019619 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019620 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019621 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019622 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019623 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019624 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019625 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019626 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019627 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019628 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019629 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019630 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019631 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019632 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019633 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019634 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019635 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019640 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019641 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019642 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019643 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019644 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019645 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019646 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019647 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019648 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019649 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019652 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019654 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019655 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019656 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019657 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019658 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019659 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019660 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019661 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019662 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019663 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019664 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019665 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019666 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019667 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019669 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019670 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019671 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019672 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019673 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019674 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019675 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019676 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019677 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0019678 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019679 -->

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        <rdfs:label>Bordetella pertussis as vaccine component</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0019680 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019681 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019682 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019683 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019684 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019685 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019686 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019687 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019688 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019689 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019690 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019691 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019692 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019693 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019694 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019695 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019696 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019697 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019698 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019699 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019700 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019701 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019702 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019703 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019704 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019705 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019706 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019707 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019708 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019709 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019710 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019711 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019712 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019713 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019714 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019715 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019716 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019717 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019718 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019720 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019721 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019722 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019723 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019724 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019725 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019726 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019727 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019728 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019729 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019730 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019731 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019732 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019733 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019734 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019735 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019736 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019737 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019738 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019739 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019740 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019743 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019744 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019745 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019746 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019747 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019748 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019749 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019750 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019752 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019753 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019754 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019755 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019756 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019757 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019758 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019759 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019760 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019761 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019762 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019763 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019764 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019765 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019766 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019767 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019768 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019769 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019770 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019771 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019772 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019773 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019774 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019775 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019776 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019777 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019778 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019779 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019780 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019781 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019782 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019783 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019784 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019785 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019786 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019787 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019788 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019789 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019790 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019791 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019792 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019793 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019794 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019795 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019796 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019797 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019798 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019799 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019800 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019801 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019802 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019803 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019804 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019805 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019806 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019807 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019808 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019809 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019810 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019811 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019812 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019813 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019814 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019815 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019816 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019817 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019818 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019819 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019820 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019821 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019822 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019823 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019824 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019825 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019826 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019827 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019830 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019831 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019832 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019833 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019834 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019835 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019836 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019837 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019838 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019839 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019840 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019841 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019842 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019843 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019844 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019845 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019846 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019847 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019848 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019849 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019850 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019851 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019852 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019853 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019854 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019855 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019856 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019857 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019858 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019859 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019860 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019861 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019862 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019863 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019864 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019865 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019866 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019872 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019876 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019879 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019883 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019884 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019885 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019887 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019889 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019892 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019893 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019894 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019895 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019896 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019897 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019898 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019899 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019900 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019901 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019902 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019903 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019904 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019905 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019906 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019907 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019908 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019909 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019910 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019911 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019912 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019913 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019914 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019917 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019918 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019919 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019920 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019921 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019923 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019924 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019925 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019926 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019927 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019928 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019930 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019931 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019932 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019933 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019934 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019935 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019936 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019938 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019939 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019940 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019941 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019942 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019947 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019948 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019953 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019956 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019957 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019958 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019959 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019961 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019966 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019967 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019968 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019969 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019970 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019971 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019972 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019977 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019979 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019990 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019991 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019992 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019993 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019994 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019995 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019996 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019998 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0019999 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020000 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020001 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020002 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020003 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020004 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020005 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020006 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020007 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020008 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020009 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020010 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020011 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020012 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020013 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020014 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020016 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020017 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020018 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020019 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020020 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020028 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020029 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020030 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020032 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020033 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020034 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020035 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020037 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020039 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020046 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020060 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020065 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020069 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020071 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020080 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020089 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020090 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0020091 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020092 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020093 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020094 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020095 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020096 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020097 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020098 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020099 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020100 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020101 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020102 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020103 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020104 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020105 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020106 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020109 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020110 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020112 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020113 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020114 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020115 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020116 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020117 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020118 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020119 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020120 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020121 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020122 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020123 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020124 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020125 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020126 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020127 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020128 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020129 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020130 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020131 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020132 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020133 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020134 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020135 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020136 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020137 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020138 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020139 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020158 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020159 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020160 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020161 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020162 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020163 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020164 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020172 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020173 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020176 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020177 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020178 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020179 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020180 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020181 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020183 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020188 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020189 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020190 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020191 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020192 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020193 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020194 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020195 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020196 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020197 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020199 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020200 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020201 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020202 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020203 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020204 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020205 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020206 -->

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        <rdfs:label>SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.2 MG/ML Injectable Suspension [Spikevax]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0020207 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020208 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020209 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020210 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020211 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020212 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020213 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020214 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020215 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020216 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020217 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020218 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020219 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020220 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020221 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020222 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020223 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020224 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020225 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020226 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020227 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020228 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020229 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020230 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020232 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020233 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020234 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020239 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020240 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020258 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020262 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020264 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020266 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020268 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020269 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020270 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020271 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020272 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020273 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020273</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>tetanus toxoid vaccine, inactivated 5 LFU Injectable Solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020274 -->

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            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_11338"/>
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        <obo:VO_0003560>tetanus toxoid vaccine, inactivated Injectable Solution [TE Anatoxal Berna]</obo:VO_0003560>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>tetanus toxoid vaccine, inactivated Injectable Solution [TE Anatoxal Berna]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020275 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020275">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020275</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0020469"/>
        <rdfs:label>obsolete typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020276 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020276">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020276</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <rdfs:label>obsolete typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
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    <!-- http://purl.obolibrary.org/obo/VO_0020277 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020277</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0020470"/>
        <rdfs:label>obsolete typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typhim VI]</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020278 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <rdfs:label>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Injectable Solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020279 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Injectable Solution [Typhim VI]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020280">
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020281 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020282 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020283 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020284 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020285 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020286 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020287 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020288 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020289 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020290 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020291 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020292 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020293 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020294 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020295 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020296 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020297 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020298 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020299 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020301 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020310 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020311 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020314 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020315 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020316 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020317 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020318 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020319 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020320 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020321 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020322 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020323 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020324 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020325 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020326 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020329 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020330 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020331 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020332 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020333 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020334 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020335 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020336 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020342 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020345 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020351 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020352 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020353 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020359 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020360 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020361 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020362 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020363 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020364 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020365 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020366 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020367 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020368 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020369 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020370 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020377 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020378 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020379 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020380 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020381 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020382 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020383 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020389 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020390 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020391 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020392 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020393 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020394 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020395 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020401 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020402 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020403 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020404 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020405 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020406 -->

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        <obo:VO_0010152>OMOP740521</obo:VO_0010152>
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        <rdfs:label>1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 20</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020407 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020407</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003560>1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 50</obo:VO_0003560>
        <obo:VO_0010151>43770504</obo:VO_0010151>
        <obo:VO_0010152>OMOP740523</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 50</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020408 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020409 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020409</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
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        <rdfs:label>obsolete 0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI]</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020410 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020410</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0010152>OMOP5207894</obo:VO_0010152>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020411 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020411</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typherix]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020412 -->

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        <rdfs:label>1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension Box of 10</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020413 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020414 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020415 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020416 -->

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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 100</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020419 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020419</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003560>Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 50</obo:VO_0003560>
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        <obo:VO_0010152>OMOP707743</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] Box of 50</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020420 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020420">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020420</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0020421"/>
        <rdfs:label>obsolete Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020421 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020392"/>
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            <owl:Restriction>
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            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020421</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0010152>OMOP4707289</obo:VO_0010152>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020422 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020422">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020422</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
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        <rdfs:label>obsolete Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020423 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020423</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0010151>36947181</obo:VO_0010151>
        <obo:VO_0010151>40749996</obo:VO_0010151>
        <obo:VO_0010152>OMOP4707290</obo:VO_0010152>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020424 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020393"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typherix] Box of 1</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020425 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020426 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020427 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020428 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020429 -->

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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018837"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020431</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] by Glaxosmithkline</obo:VO_0003560>
        <obo:VO_0010151>43738118</obo:VO_0010151>
        <obo:VO_0010152>OMOP719054</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typherix] by Glaxosmithkline</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020432 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020432">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020432</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0020433"/>
        <rdfs:label>obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Sanofi</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020433 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020433">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020410"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0018838"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020433</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Sanofi</obo:VO_0003560>
        <obo:VO_0010151>36934225</obo:VO_0010151>
        <obo:VO_0010151>43594110</obo:VO_0010151>
        <obo:VO_0010152>OMOP5207895</obo:VO_0010152>
        <obo:VO_0010152>OMOP719052</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Sanofi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020434 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020434">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020434</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0020435"/>
        <rdfs:label>obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Waymade</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020435 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020435">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020410"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020435</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
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        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Waymade</obo:VO_0003560>
        <obo:VO_0010151>36952652</obo:VO_0010151>
        <obo:VO_0010151>40719395</obo:VO_0010151>
        <obo:VO_0010152>OMOP4737834</obo:VO_0010152>
        <obo:VO_0010152>OMOP5207896</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] by Waymade</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020436 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020436">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020405"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015018"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020436</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_13258"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_90370"/>
        <obo:VO_0003560>1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 10 by Glaxosmithkline</obo:VO_0003560>
        <obo:VO_0010151>43698680</obo:VO_0010151>
        <obo:VO_0010152>OMOP740520</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 10 by Glaxosmithkline</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020437 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020437">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020406"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015018"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020437</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0010151>43734586</obo:VO_0010151>
        <obo:VO_0010152>OMOP740522</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015072"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>1 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML Injectable Suspension [Hepatyrix] Box of 20 by Glaxosmithkline</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020438 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020438">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020407"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020438</metadata:prefixIRI>
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    <!-- http://purl.obolibrary.org/obo/VO_0020439 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020440 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020441 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020442 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020443 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020444 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020444</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0010152>OMOP4737835</obo:VO_0010152>
        <obo:VO_0010152>OMOP5207897</obo:VO_0010152>
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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020445 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
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        <rdfs:label>obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 1</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0020446 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0020447"/>
        <rdfs:label>obsolete 0.5 ML typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI] Box of 10</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
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    <!-- http://purl.obolibrary.org/obo/VO_0020447 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0020448 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020449 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020450 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020457 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020458 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020459 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020459</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0020460 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020461 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020462 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020463 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020464 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020465 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
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    <!-- http://purl.obolibrary.org/obo/VO_0020466 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020467 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020468 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020469 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020470 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020471 -->

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        <rdfs:subClassOf>
            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020471</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluvirin 2011-2012 Formula vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020472 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020472">
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0003855"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020280"/>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020472</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003198>1359739</obo:VO_0003198>
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        <obo:VO_0003560>typhoid Vi polysaccharide vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe</obo:VO_0003560>
        <obo:VO_0010151>42902626</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020473 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020473">
        <owl:equivalentClass>
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                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019032"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000001"/>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010418"/>
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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
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            <owl:Restriction>
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            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020473</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluvirin 2012-2013 Formula vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020474 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020474">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020470"/>
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            <owl:Restriction>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020474</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typhim VI]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020475 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020475">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020475</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
        <obo:IAO_0000233 rdf:resource="https://github.com/vaccineontology/VO/issues/737"/>
        <obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/VO_0019351"/>
        <rdfs:label>obsolete 0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020476 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020476">
        <owl:equivalentClass>
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                        <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0019033"/>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020476</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluvirin 2013-2014 Formula vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020477 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020477">
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020477</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluvirin 2014-2015 Formula vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020478 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020478">
        <owl:equivalentClass>
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    <!-- http://purl.obolibrary.org/obo/VO_0020480 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020481 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020484 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020485 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020486 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020487 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020489 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020490 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020491 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020492 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020493 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020494 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020494</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2022 Southern Hemisphere vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020495 -->

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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020495</metadata:prefixIRI>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2022-2023 vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0020496 -->

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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone Quadrivalent 2023 Southern Hemisphere vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0020497 -->

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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS-CoV-2 (COVID-19) vaccine, mRNA-1273</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0020498 -->

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        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>SARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020499 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020499">
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1364467</obo:VO_0003198>
        <obo:VO_0003560>Haemophilus influenzae</obo:VO_0003560>
        <obo:VO_0010151>43012721</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020500 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020500">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1491863</obo:VO_0003198>
        <obo:VO_0003560>hepatitis C virus</obo:VO_0003560>
        <obo:VO_0010151>44814323</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>hepatitis C virus as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020501 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020501">
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1312375</obo:VO_0003198>
        <obo:VO_0003560>influenza A virus</obo:VO_0003560>
        <obo:VO_0010151>42903441</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza A virus as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020502 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020502">
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1312376</obo:VO_0003198>
        <obo:VO_0003560>influenza B virus</obo:VO_0003560>
        <obo:VO_0005279>influenza B virus whole</obo:VO_0005279>
        <obo:VO_0010151>42903442</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>influenza B virus as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020503 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020503">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1439114</obo:VO_0003198>
        <obo:VO_0003560>Japanese encephalitis virus</obo:VO_0003560>
        <obo:VO_0010151>44506749</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Japanese encephalitis virus as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020504 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020504">
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>7288</obo:VO_0003198>
        <obo:VO_0003560>Neisseria meningitidis</obo:VO_0003560>
        <obo:VO_0010151>515671</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Neisseria meningitidis as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020505 -->

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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1648419</obo:VO_0003198>
        <obo:VO_0003560>rabies virus</obo:VO_0003560>
        <obo:VO_0010151>46234308</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>rabies virus as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020506 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020506">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020506</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1744460</obo:VO_0003198>
        <obo:VO_0003560>Rickettsia prowazekii</obo:VO_0003560>
        <obo:VO_0010151>35603526</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Rickettsia prowazekii as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020507 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020507">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020507</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1365969</obo:VO_0003198>
        <obo:VO_0003560>rubella virus</obo:VO_0003560>
        <obo:VO_0010151>43012953</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>rubella virus as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020508 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020508">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020508</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1432993</obo:VO_0003198>
        <obo:VO_0003560>Yersinia pestis</obo:VO_0003560>
        <obo:VO_0010151>43560347</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Yersinia pestis as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020509 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020509">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020509</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>50937</obo:VO_0003198>
        <obo:VO_0003560>Haemophilus influenzae type b</obo:VO_0003560>
        <obo:VO_0010151>19113026</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Haemophilus influenzae type b as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020510 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020510">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020510</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1491862</obo:VO_0003198>
        <obo:VO_0003560>hepatitis A virus</obo:VO_0003560>
        <obo:VO_0010151>44814322</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>hepatitis A virus as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020511 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020511">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020511</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1427211</obo:VO_0003198>
        <obo:VO_0003560>hepatitis B virus</obo:VO_0003560>
        <obo:VO_0010151>43532406</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>hepatitis B virus as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020512 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020512">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020512</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1427212</obo:VO_0003198>
        <obo:VO_0003560>poliovirus</obo:VO_0003560>
        <obo:VO_0010151>43532418</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>poliovirus as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020513 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020513">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000420"/>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020513</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:VO_0003198>1432992</obo:VO_0003198>
        <obo:VO_0003560>Vibrio cholerae</obo:VO_0003560>
        <obo:VO_0010151>43560345</obo:VO_0010151>
        <oboInOwl:inSubset>vaccine component</oboInOwl:inSubset>
        <rdfs:label>Vibrio cholerae as vaccine component</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020514 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020514">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020699"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020514</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0010038"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
        <obo:VO_0003560>0.1 ML BCG, Live, Connaught Strain 1 MG/ML Injectable Solution</obo:VO_0003560>
        <obo:VO_0010151>44132415</obo:VO_0010151>
        <obo:VO_0010152>OMOP1127046</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.1 ML BCG, Live, Connaught Strain 1 MG/ML Injectable Solution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020515 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020515">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020514"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
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            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
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        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
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        </rdfs:subClassOf>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020515</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_399"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_1765"/>
        <obo:VO_0003560>0.1 ML BCG, Live, Connaught Strain 1 MG/ML Injectable Solution by Sanofi</obo:VO_0003560>
        <obo:VO_0010151>44132431</obo:VO_0010151>
        <obo:VO_0010152>OMOP1127062</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015073"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.1 ML BCG, Live, Connaught Strain 1 MG/ML Injectable Solution by Sanofi</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020516 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020516">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020946"/>
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            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <rdfs:subClassOf>
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            <owl:Restriction>
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        <rdfs:subClassOf>
            <owl:Restriction>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
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        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0020516</metadata:prefixIRI>
        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
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        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11520"/>
        <obo:VO_0003560>0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML Nasal Spray</obo:VO_0003560>
        <obo:VO_0010151>44132442</obo:VO_0010151>
        <obo:VO_0010152>OMOP1127073</obo:VO_0010152>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0019100"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML Nasal Spray</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020517 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0020517">
        <owl:equivalentClass>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0020516"/>
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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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        <obo:VO_0003560>0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML Nasal Spray [FluMist Quadrivalent]</obo:VO_0003560>
        <obo:VO_0010151>44132460</obo:VO_0010151>
        <obo:VO_0010152>OMOP1127091</obo:VO_0010152>
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        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.2 ML influenza A-California-7-2009-(H1N1)v-like virus vaccine 160000000 /ML / influenza B virus antigen 160000000 /ML Nasal Spray [FluMist Quadrivalent]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020518 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020519 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0020520 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020521 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020522 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020523 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020524 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020525 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020526 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020527 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020528 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020529 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020530 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020531 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020532 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020533 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020538 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020542 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020543 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020544 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020545 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020546 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020548 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020549 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020550 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020551 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020552 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020564 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020565 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020568 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020569 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020570 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020571 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020572 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020573 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020574 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020575 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020576 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020578 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020579 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020580 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020581 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020582 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020583 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020600 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020601 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020609 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020610 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020611 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020612 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020613 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020614 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020615 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020616 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020617 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020618 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020619 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020620 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020621 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020622 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020623 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020624 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020625 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020626 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020627 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020628 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020629 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020630 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020631 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020632 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020633 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020634 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020635 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020636 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020637 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020638 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020639 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020640 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020641 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020642 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020643 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020644 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020645 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020646 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020667 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020668 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020670 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020672 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020673 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020674 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020675 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020676 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020677 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020678 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020679 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020681 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020682 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020683 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020684 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020685 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020686 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020687 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020688 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020697 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020698 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020699 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020700 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020701 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020702 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020703 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020708 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020709 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020710 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020711 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020712 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020713 -->

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        <obo:VO_0003560>BCG, Live, Connaught Strain 1920000000 CFU Injection [ImmuCyst]</obo:VO_0003560>
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    <!-- http://purl.obolibrary.org/obo/VO_0020714 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0020715 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020716 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020717 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020718 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020719 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020720 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020721 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020722 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020723 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020724 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020725 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020726 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020727 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020728 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020729 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020730 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020731 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020732 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020733 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020734 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020735 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020736 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020737 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020738 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020739 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020740 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020741 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020742 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020743 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020744 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020745 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020746 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020747 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020752 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020753 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020754 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020755 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020756 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020757 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020758 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020759 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020761 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020763 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020764 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020765 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020766 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020767 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020768 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020769 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020770 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020771 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020772 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020774 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020775 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020776 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020777 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020785 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020786 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020787 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020788 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020791 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020792 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020793 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020794 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020795 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020796 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020798 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020807 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020809 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020810 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020811 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020833 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020834 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020835 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020836 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020837 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020838 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020839 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020840 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020841 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020842 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020843 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020844 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020845 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020846 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020847 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020848 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020849 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020850 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020851 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020852 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020853 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020854 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020855 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020856 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020857 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020858 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020859 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020860 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020861 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020862 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020864 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020876 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020881 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020882 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020883 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020884 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020890 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020891 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020892 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020893 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020894 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020895 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020896 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020897 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020898 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020899 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020900 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020901 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020902 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020903 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020904 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020905 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020906 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020907 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020908 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020909 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020910 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020911 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020912 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020913 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020914 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020915 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020918 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020919 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020920 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020921 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020922 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020923 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020924 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020925 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020926 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020927 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020928 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020929 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020930 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020931 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020932 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020933 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020934 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020935 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020936 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020937 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020938 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020939 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020940 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020941 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020942 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020943 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020944 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020945 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020947 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020948 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020949 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020950 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020951 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020952 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020953 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020954 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020955 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020962 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020963 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020964 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020965 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020966 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020968 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020969 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020970 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020971 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020972 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020976 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020977 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020978 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020979 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020980 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020981 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020982 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020983 -->

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        <obo:IAO_0000117>OHDSI Vaccine WG</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0020984 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020985 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020986 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020987 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020988 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020989 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020990 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020991 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020992 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020993 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020994 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020995 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020996 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020997 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020998 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0020999 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021000 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021001 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021002 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021003 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021004 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021005 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021006 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021007 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021008 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021009 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021010 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021011 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021012 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021013 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021014 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021015 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021016 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021017 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021018 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021019 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021020 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021021 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021022 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021023 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021024 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021025 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021026 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021027 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021028 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021030 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021031 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021032 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021033 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021035 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021038 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021041 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021042 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021043 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021044 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021048 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021096 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021097 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021098 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021099 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021100 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021101 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021102 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021103 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021104 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021105 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021106 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021107 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021108 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021109 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021110 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021111 -->

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    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021112 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021113 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021114 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021115 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021116 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021117 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021118 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021119 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021120 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021121 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021122 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021123 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021124 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021125 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021126 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021127 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021128 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021129 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021130 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021131 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021132 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021133 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021134 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021135 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021136 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021137 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021138 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021139 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021140 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021141 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021142 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021143 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021144 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021145 -->

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        <rdfs:label>Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Quadracel]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0021164 -->

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        <obo:IAO_0000115>A varicella-zoster virus live vaccine designed to prevent shingles (herpes zoster). </obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0021165 -->

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        <obo:IAO_0000115>A varicella-zoster virus vaccine, also known as the chickenpox vaccine, that protects against the varicella-zoster virus (VZV) causes chickenpox.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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        <rdfs:label>varicella virus vaccine</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/VO_0021166 -->

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        <obo:IAO_0000115>A DTP-Haemophilus influenzae type b conjugate and hepatitis B vaccine that is used outside USA.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0021167 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0021168 -->

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        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
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    <!-- http://purl.obolibrary.org/obo/VO_0021169 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021170 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021172 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021173 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021174 -->

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    <!-- http://purl.obolibrary.org/obo/VO_0021175 -->

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            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010460"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0021177</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2664811</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0010460"/>
        <obo:VO_0003560>0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Prefilled Syringe</obo:VO_0003560>
        <obo:VO_0010151>747824</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Prefilled Syringe</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0021178">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0021176"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010460"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0021178</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2664822</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0010460"/>
        <obo:VO_0003560>0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Injection [Spikevax 2023-2024]</obo:VO_0003560>
        <obo:VO_0010151>747827</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015074"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Injection [Spikevax 2023-2024]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021179 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0021179">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0021177"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0010460"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015007"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0015002"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010459"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0021179</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Yuanyi Pan</obo:IAO_0000117>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0007747"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_0080600"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003198>2664817</obo:VO_0003198>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/VO_0010460"/>
        <obo:VO_0003560>0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Prefilled Syringe [Spikevax 2023-2024]</obo:VO_0003560>
        <obo:VO_0010151>747825</obo:VO_0010151>
        <obo:VO_0015007 rdf:resource="http://purl.obolibrary.org/obo/VO_0015065"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>0.5 ML SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 OMICRON (XBB.1.5) 0.1 MG/ML Prefilled Syringe [Spikevax 2023-2024]</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021180 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/VO_0021180">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0000079"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/VO_0010426"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001011"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0001243"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0003355"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/VO_0010396"/>
                <owl:hasValue rdf:resource="http://purl.obolibrary.org/obo/VO_0010407"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VO:0021180</metadata:prefixIRI>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/766</obo:IAO_0000233>
        <obo:RO_0000085 rdf:resource="http://purl.obolibrary.org/obo/VO_0000452"/>
        <obo:RO_0000087 rdf:resource="http://purl.obolibrary.org/obo/VO_0000630"/>
        <obo:VO_0001011 rdf:resource="http://purl.obolibrary.org/obo/DOID_8469"/>
        <obo:VO_0001243 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_11320"/>
        <obo:VO_0003355 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_197912"/>
        <oboInOwl:inSubset>vaccine</oboInOwl:inSubset>
        <rdfs:label>Fluzone High-Dose 2010-2011 vaccine</rdfs:label>
    </owl:Class>
    


    <!-- http://www.w3.org/2002/07/owl#Thing -->

    <rdf:Description rdf:about="http://www.w3.org/2002/07/owl#Thing">
        <metadata:prefixIRI rdf:datatype="http://www.w3.org/2001/XMLSchema#string">owl:Thing</metadata:prefixIRI>
    </rdf:Description>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Individuals
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/IAO_0000002 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000002">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
        <obo:IAO_0000111 xml:lang="en">example to be eventually removed</obo:IAO_0000111>
        <rdfs:label xml:lang="en">example to be eventually removed</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000103 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000103">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
        <obo:IAO_0000111 xml:lang="en">failed exploratory term</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Person:Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">failed exploratory term</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000120 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000120">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
        <obo:IAO_0000111 xml:lang="en">metadata complete</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">metadata complete</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000121 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000121">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
        <obo:IAO_0000111 xml:lang="en">organizational term</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Term created to ease viewing/sort terms for development purpose, and will not be included in a release</obo:IAO_0000115>
        <rdfs:label xml:lang="en">organizational term</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000122 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000122">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
        <obo:IAO_0000111 xml:lang="en">ready for release</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking &quot;ready_for_release&quot; should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed &quot;ready_for_release&quot; will also derived from a chain of ancestor classes that are also &quot;ready_for_release.&quot;</obo:IAO_0000115>
        <rdfs:label xml:lang="en">ready for release</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000123 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000123">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
        <obo:IAO_0000111 xml:lang="en">metadata incomplete</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">metadata incomplete</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000124 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000124">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
        <obo:IAO_0000111 xml:lang="en">uncurated</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Nothing done yet beyond assigning a unique class ID and proposing a preferred term.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">uncurated</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000125 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000125">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
        <obo:IAO_0000111 xml:lang="en">pending final vetting</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">pending final vetting</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000224 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000224">
        <obo:IAO_0000115 xml:lang="en">Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
        <rdfs:label xml:lang="en">obsolete_core</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000226 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000226">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
        <obo:IAO_0000111 xml:lang="en">placeholder removed</obo:IAO_0000111>
        <rdfs:label xml:lang="en">placeholder removed</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000227 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000227">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
        <obo:IAO_0000111 xml:lang="en">terms merged</obo:IAO_0000111>
        <obo:IAO_0000116 xml:lang="en">An editor note should explain what were the merged terms and the reason for the merge.</obo:IAO_0000116>
        <rdfs:label xml:lang="en">terms merged</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000228 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000228">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
        <obo:IAO_0000111 xml:lang="en">term imported</obo:IAO_0000111>
        <obo:IAO_0000116 xml:lang="en">This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use.</obo:IAO_0000116>
        <rdfs:label xml:lang="en">term imported</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000229 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000229">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
        <obo:IAO_0000111 xml:lang="en">term split</obo:IAO_0000111>
        <obo:IAO_0000116 xml:lang="en">This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created.</obo:IAO_0000116>
        <rdfs:label xml:lang="en">term split</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000410 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000410">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000409"/>
        <obo:IAO_0000111 xml:lang="en">universal</obo:IAO_0000111>
        <obo:IAO_0000116 xml:lang="en">Hard to give a definition for. Intuitively a &quot;natural kind&quot; rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf</obo:IAO_0000119>
        <rdfs:label xml:lang="en">universal</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000420 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000420">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000409"/>
        <obo:IAO_0000111 xml:lang="en">defined class</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">&quot;definitions&quot;, in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">defined class</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000421 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000421">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000409"/>
        <obo:IAO_0000111 xml:lang="en">named class expression</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A named class expression is a logical expression that is given a name. The name can be used in place of the expression.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <rdfs:label xml:lang="en">named class expression</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000423 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000423">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
        <obo:IAO_0000111 xml:lang="en">to be replaced with external ontology term</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">Terms with this status should eventually replaced with a term from another ontology.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">group:OBI</obo:IAO_0000119>
        <rdfs:label xml:lang="en">to be replaced with external ontology term</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000428 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/IAO_0000428">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000078"/>
        <obo:IAO_0000111 xml:lang="en">requires discussion</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">group:OBI</obo:IAO_0000119>
        <rdfs:label xml:lang="en">requires discussion</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0001000 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OMO_0001000">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
        <obo:IAO_0000115 xml:lang="en">The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">This obsolesence reason should be used conservatively. Typical valid examples are: un-necessary grouping classes in disease ontologies, a phenotype term added on the assumption it was a disease.</obo:IAO_0000116>
        <obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0001-5208-3432"/>
        <obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/77</obo:IAO_0000233>
        <obo:IAO_0000234>https://orcid.org/0000-0001-5208-3432</obo:IAO_0000234>
        <rdfs:label>out of scope</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/OMO_0001002 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/OMO_0001002">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/IAO_0000225"/>
        <obo:IAO_0000115 xml:lang="en">The term was added to the ontology on the assumption it was a valid domain entity, but it turns out the entity does not exist in reality.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">This obsolesence reason should be used conservatively. For example: Obsoleting class that describes a breed of cow based on a record in an existing database, that was later retracted as faulty (breed does not exist). Do not use this term to obsolete a historic concept (that was once valid, but not anymore). </obo:IAO_0000116>
        <obo:IAO_0000117 rdf:resource="http://orcid.org/0000-0002-4142-7153"/>
        <obo:IAO_0000233>https://github.com/information-artifact-ontology/ontology-metadata/issues/136</obo:IAO_0000233>
        <obo:IAO_0000234>https://orcid.org/0000-0002-4142-7153</obo:IAO_0000234>
        <rdfs:label>domain entity does not exist</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000023 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000023">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Invitrogen</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000056 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000056">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>United Vaccines, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000057 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000057">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Heska Corporation</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000058 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000058">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Texas Vet lab, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000059 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000059">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>SolidTech Animal Health, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000060 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000060">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>MVP Laboratories, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000061 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000061">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Addison Biological Laboratory, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000062 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000062">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000119>neotechvaccines.com</obo:IAO_0000119>
        <rdfs:label>Neotech, LLC</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000149 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000149">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Aceto Pharma Corp</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000204 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000204">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000116>Intervet has merged with Schering-Plough Animal Health  and become Intervet/Schering-Plough Animal Health™ (YL.)</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Intervet</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000205 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000205">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Fort Dodge</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000264 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000264">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000119>www.protatek.com</obo:IAO_0000119>
        <rdfs:label>ProtaTek International, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000265 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000265">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000119>www.arkolabs.com</obo:IAO_0000119>
        <rdfs:label>Arko Laboratories Ltd</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000268 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000268">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000119>www.newportlabs.com</obo:IAO_0000119>
        <rdfs:label>Newport Laboratories, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000269 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000269">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Texas Agricultural Experiment Station</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000296 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000296">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Brinton Laboratories Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000570 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000570">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <rdfs:label>Novartis Animal Health US, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000607 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000607">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Intercell Biomedical</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000686 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000686">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Acambis, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000687 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000687">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Berna Biotech, Ltd</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000688 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000688">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>BioPort Corp</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000689 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000689">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>CSL Limited</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000690 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000690">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A British multinational pharmaceutical company headquartered in Brentford, England</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">GSK</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/GlaxoSmithKline</obo:IAO_0000119>
        <rdfs:label>GlaxoSmithKline plc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000691 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000691">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Greer Laboratories Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000693 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000693">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Massachusetts Public Health Biologic Lab</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000694 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000694">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>MedImmune Vaccines, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000695 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000695">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">Merck Sharp &amp; Dohme Corp.</obo:IAO_0000118>
        <rdfs:label>Merck &amp; Co., Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000696 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000696">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Novartis Vaccines and Diagnostics</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000697 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000697">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000116>100 Rodolphe Street
Building 1300
Durham, NC 27712</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Organon Teknika Corp LLC</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000698 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000698">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Research Foundation for Microbial Diseases of Osaka University</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000699 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000699">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Sanofi Pasteur Limited</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000700 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000700">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Sanofi Pasteur, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000701 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000701">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Wyeth Pharmaceuticals Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000703 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000703">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Sanofi Pasteur, SA</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000821 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000821">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Vetech Labs</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000841 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000841">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Pfizer Animal Health</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000846 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000846">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>BIOPHARM</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000848 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000848">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Cutter Biological</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000861 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000861">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Bioproperties</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000869 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000869">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Solvay Pharmaceuticals</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000877 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000877">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Websters Animal Health</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000890 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000890">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Colorado Serum Company CZ Veterinaria</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000892 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000892">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Biken</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000893 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000893">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Schering-Plough</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000895 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000895">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Baxter Healthcare Corporation</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000896 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000896">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Merck Frosst</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000901 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000901">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Boehringer-Ingelheim Vetmedica, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000904 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000904">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>SBL Vaccine</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000905 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000905">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Allen Xiang</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Wyeth Canada</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000914 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000914">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Virbac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000959 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000959">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Embrex</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000964 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000964">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Novartis Animal Health</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000971 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000971">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">Aqua Health</obo:IAO_0000118>
        <rdfs:label>Novartis</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0000989 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0000989">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Novus International</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001001 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001001">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Biomune</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001006 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001006">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Vical, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001010 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001010">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Promega</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001027 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001027">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Lohman Animal Health International</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001058 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001058">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Centre for Ticks and Tickborne Disease, Malawi</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001069 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001069">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>ImmunoVaccine Technologies, Canada</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001079 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001079">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Local veterinary institutes</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001092 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001092">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000450"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">United States Department of Agriculture</obo:IAO_0000118>
        <rdfs:label>USDA</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001119 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001119">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Merial, Inc</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001174 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001174">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000116>Intervet has merged with Schering-Plough Animal Health  and become Intervet/Schering-Plough Animal Health‚Ñ¢ (YL.)</obo:IAO_0000116>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Schering-Plough Animal Health</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001179 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001179">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Bayer Leverkusen</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001212 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001212">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Coopers Animal Health</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001219 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001219">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Dow AgroSciences</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001458 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001458">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.duckhealth.com/idrc.html</obo:IAO_0000119>
        <rdfs:label>International Duck Research Cooperative, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0001529 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0001529">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <rdfs:comment>Vaccicel, Inc. has a location in Belton, TX. Active officers include Andre Menchu, Andres Menchu, Kathryn M Baker, Katheryn Becker and Andres Menches. Vaccicel, Inc. filed as a Domestic For-Profit Corporation on Tuesday, August 22, 1995 in the state of Texas and is currently active. Andres Menchu serves as the registered agent for this organization.The company&apos;s line of business includes Mfg Research &amp; Development Veterinary Bacterial Vaccines. 
(http://www.corporationwiki.com/Texas/Belton/vaccicel-inc/34296230.aspx)</rdfs:comment>
        <rdfs:label>VacciCel, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0002498 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0002498">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <rdfs:comment>GSK Acquires Influenza Vaccine Manufacturer ID Biomedical Corporation
http://www.medicalnewstoday.com/releases/34803.php

GlaxoSmithKline plc (NYSE:GSK) announced the completion of the acquisition of ID Biomedical. This follows regulatory clearances of the transaction and adoption of the acquisition agreement by ID Biomedical&apos;s shareholders (which occurred on the 16th of November). ID Biomedical becomes a wholly-owned subsidiary of GSK. ...</rdfs:comment>
        <rdfs:label>ID Biomedical Corporation of Quebec</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003069 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003069">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000119>http://www.proteinsciences.com/</obo:IAO_0000119>
        <rdfs:label>Protein Sciences Corporation</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003076 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003076">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Valneva SE</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003078 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003078">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>An Israeli research and development laboratory</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Israel_Institute_for_Biological_Research</obo:IAO_0000119>
        <rdfs:label>Israel Institute for Biological Research</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003079 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003079">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>PaxVax, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003089 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003089">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:comment>Out of buisness</rdfs:comment>
        <rdfs:label>Lederle Laboratories Division</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003123 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003123">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Abbot Laboratories</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003125 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003125">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Parke, Davis, Company</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003132 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003132">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Max Planck Institute for Infection Biology</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003137 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003137">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Bio-Manguinhos</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003145 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003145">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Mylan Products Limited</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003149 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003149">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>French National Agency for Research on AIDS and Viral Hepatitis (ANRS)</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003153 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003153">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A company trhat is located at Berkeley, CA, USA. Its website is: http://www.dynavax.com.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Randi Vita</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.dynavax.com/</obo:IAO_0000119>
        <rdfs:label>Dynavax Technologies Corporation</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003157 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003157">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>Novavax, Inc. is a clinical-stage biotechnology company committed to delivering novel products to prevent a broad range of infectious diseases.</obo:IAO_0000115>
        <obo:IAO_0000119>http://novavax.com/</obo:IAO_0000119>
        <rdfs:label>Novavax, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003163 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003163">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Teva Pharmaceuticals USA, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003164 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003164">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Seqirus, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003166 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003166">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>Located in Swiftwater, Pennsylvania, this company is now known as Sanofi Pasteur Limited.</obo:IAO_0000115>
        <obo:IAO_0000117>Kallan Roan</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>Connaught Laboratories, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0003179 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0003179">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <rdfs:label>Chiron Behring Vaccines Private Ltd</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004892 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004892">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000119>https://www.advent-gmp.com/about-us/</obo:IAO_0000119>
        <rdfs:comment>ADVENT SRL
VIA CRESCENZIO 9
ROMA, ROMA, 00193  Italy
+39-0691093692
Company Type: Corporation Subsidiary
http://www.hoovers.com/company-information/cs/company-profile.advent_srl.aebb99e74ae57b09.html?aka_re=1</rdfs:comment>
        <rdfs:label>Advent Srl., Italy</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004932 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004932">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A pharmaceutical company that was founded in 1953 by Paul Janssen, is headquartered in Beerse, Belgium, and owned by Johnson &amp; Johnson.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Janssen_Pharmaceutica</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.janssen.com/us/</obo:IAO_0000119>
        <rdfs:label>Janssen Pharmaceutica</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004945 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004945">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="zh">康希诺生物</obo:IAO_0000118>
        <obo:IAO_0000119>http://www.cansinotech.com/</obo:IAO_0000119>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/CanSino_Biologics</obo:IAO_0000119>
        <rdfs:label>CanSino Biologics</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004946 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004946">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A German biotechnology company that is dedicated to the development and manufacture of active immunotherapies for a patient-specific approach to the treatment of serious diseases.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/BioNTech</obo:IAO_0000119>
        <rdfs:label>BioNTech</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004947 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004947">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>An American multinational pharmaceutical corporation headquartered in New York City.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Pfizer</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.pfizer.com/</obo:IAO_0000119>
        <rdfs:label>Pfizer Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004948 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004948">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A British-Swedish multinational pharmaceutical and biopharmaceutical company with its headquarters in Cambridge, United Kingdom and Sodertalje, Sweden. AstraZeneca makes products for major disease areas including cancer, cardiovascular, gastrointestinal, infection, neuroscience, respiratory and inflammation.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/AstraZeneca</obo:IAO_0000119>
        <rdfs:label>AstraZeneca</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004949 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004949">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.cnbg.com.cn/</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.trialsitenews.com/chinas-beijing-institute-of-biological-products-covid-19-vaccine-reportedly-ready-for-phase-iii/</obo:IAO_0000119>
        <rdfs:label>Beijing Institute of Biological Products</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004950 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004950">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">Sinopharm</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">Sinopharm Group</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="zh">国药控股股份有限公司</obo:IAO_0000118>
        <obo:IAO_0000119>http://www.sinopharm.com/1156.html</obo:IAO_0000119>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Sinopharm_Group</obo:IAO_0000119>
        <rdfs:label>Sinopharm Group Co., Ltd.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004951 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004951">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>http://www.wibp.com.cn</obo:IAO_0000119>
        <rdfs:label>Wuhan Institute of Biological Products</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004952 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004952">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Gamaleya_Research_Institute_of_Epidemiology_and_Microbiology</obo:IAO_0000119>
        <obo:IAO_0000119>https://gamaleya.org/en/</obo:IAO_0000119>
        <rdfs:label>Gamaleya Research Institute</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004953 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004953">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Moderna</obo:IAO_0000119>
        <obo:IAO_0000119>https://www.modernatx.com/</obo:IAO_0000119>
        <rdfs:label>Moderna</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004954 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004954">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A biopharmaceutical company headquartered in Beijing, China</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">Sinovac</obo:IAO_0000118>
        <obo:IAO_0000119>http://www.sinovac.com/</obo:IAO_0000119>
        <rdfs:label>Sinovac Biotech Ltd</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004955 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004955">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>AnGes, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004956 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004956">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>An American biotech company focused on the discovery, development and commercialization of therapeutics for rare diseases with focus on RNA</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Arcturus_Therapeutics</obo:IAO_0000119>
        <rdfs:label>Arcturus Therapeutics</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004957 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004957">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Beijing Minhai Biotechnology Co., Ltd.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004958 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004958">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Vaxxinity</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004959 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004959">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Beijing Wantai Biological Pharmacy</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004960 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004960">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">FBRI SRC VB VECTOR</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">Federal Budgetary Research Institution State Research Center of Virology and Biotechnology</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">Vector Institute</obo:IAO_0000118>
        <rdfs:label>State Research Center of Virology and Biotechnology VECTOR</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004961 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004961">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Genexine, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004962 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004962">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>An American biotechnology company focused on the discovery, development, and commercialization of synthetic DNA products for treating cancers and infectious diseases</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Inovio_Pharmaceuticals</obo:IAO_0000119>
        <rdfs:label>Inovio Pharmaceuticals, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004963 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004963">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Kentucky Bioprocessing, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004964 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004964">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Anhui Zhifei Longcom Biopharmaceutical Co., Ltd.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004965 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004965">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A manufacturer of immunobiological drugs including vaccines in India</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Serum_Institute_of_India</obo:IAO_0000119>
        <rdfs:label>Serum Institute of India</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004966 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004966">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Zydus Cadila</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004967 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004967">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Adimmune Corporation</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004968 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004968">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A China-based company principally engaged in the research, development, production and distribution of vaccines, monoclonal antibodies and blood products</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.reuters.com/companies/300142.SZ</obo:IAO_0000119>
        <rdfs:label>Walvax Biotechnology Co., Ltd.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004969 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004969">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Symvivo</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004970 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004970">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Chulalongkorn University</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004971 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004971">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A public research university in London</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Imperial_College_London</obo:IAO_0000119>
        <rdfs:label>Imperial College London</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004972 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004972">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A Canadian biotechnology company focused on the discovery, development, and commercialization of virus-like particles using plants as &quot;bioreactors&quot; to produce proteins as candidate vaccines and medications</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Medicago_Inc.</obo:IAO_0000119>
        <rdfs:label>Medicago Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004973 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004973">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Entos Pharmaceuticals</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004974 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004974">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>ReiThera Srl</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004975 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004975">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>ImmunityBio, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004976 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004976">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>NantKwest, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004977 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004977">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>The teaching hospital of the University of Hamburg and one of the largest hospitals in Hamburg, Germany</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/University_Medical_Center_Hamburg-Eppendorf</obo:IAO_0000119>
        <rdfs:label>University Medical Center Hamburg-Eppendorf</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004978 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004978">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Medigen, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004979 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004979">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A public research university in Chengdu, Sichuan, China</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="zh">四川大学</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Sichuan_University</obo:IAO_0000119>
        <rdfs:label>Sichuan University</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004980 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004980">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Vaxine Pty Ltd.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004981 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004981">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Instituto Finlay de Vacunas</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004982 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004982">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Clover Biopharmaceuticals, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004983 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004983">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">Pasteur Institute</obo:IAO_0000118>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Pasteur_Institute</obo:IAO_0000119>
        <rdfs:label>Institut Pasteur</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004984 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004984">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>COVAXX</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004985 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004985">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A public research university located primarily in Brisbane, Queensland, Australia</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/University_of_Queensland</obo:IAO_0000119>
        <rdfs:label>University of Queensland</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004986 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004986">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>An American biotechnology company focused on the discovery, development, and commercialization of oral recombinant vaccines</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Vaxart</obo:IAO_0000119>
        <rdfs:label>Vaxart, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004997 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004997">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Cellid Co., Ltd.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0004998 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0004998">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>University Medical Center Groningen</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005080 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005080">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>AIVITA Biomedical, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005086 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005086">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>Sanofi S.A. is a French multinational pharmaceutical company headquartered in Paris, France.</obo:IAO_0000115>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://en.wikipedia.org/wiki/Sanofi</obo:IAO_0000119>
        <rdfs:label>Sanofi S.A.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005208 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005208">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.curevac.com/en/</obo:IAO_0000119>
        <rdfs:label>CureVac AG</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005209 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005209">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Research Institute for Biological Safety Problems</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005210 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005210">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Bharat Biotech International Limited</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005211 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005211">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>University of Munich (Ludwig-Maximilians)</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005212 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005212">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>West China Hospital</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005213 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005213">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>University Hospital Tuebingen</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005214 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005214">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Shenzhen Geno-Immune Medical Institute</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005215 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005215">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Providence Health &amp; Services</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005216 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005216">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>City of Hope Medical Center</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005217 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005217">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <obo:IAO_0000119>https://codagenix.com/</obo:IAO_0000119>
        <rdfs:label>Codagenix, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005218 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005218">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Center for Genetic Engineering and Biotechnology</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005219 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005219">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Biological E. Ltd</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005220 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005220">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>GeneOne Life Science, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005221 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005221">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Nanogen Pharmaceutical Biotechnology</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005222 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005222">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Shionogi</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005223 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005223">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Altimmune, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005224 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005224">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Erciyes University</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005225 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005225">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Philip Huang</obo:IAO_0000117>
        <rdfs:label>Vaccine and Infectious Disease Organization</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005280 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005280">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
        <obo:IAO_0000115>An NIAID compendium repository that stores vaccine adjuvants derived from their research studies.</obo:IAO_0000115>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000117>Wolfgang Leitner</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">VAC</obo:IAO_0000118>
        <obo:IAO_0000119>https://vac.niaid.nih.gov/</obo:IAO_0000119>
        <rdfs:label>Vaccine Adjuvant Compendium</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005564 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005564">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.dnb.com/business-directory/company-profiles.barr_laboratories_inc.5fc4bde57c6b28b4257534a1c35fe57e.html</obo:IAO_0000119>
        <rdfs:label>Barr Laboratories, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005565 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005565">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.daiichisankyo.com</obo:IAO_0000119>
        <rdfs:label>Daiichi Sankyo Co., Ltd.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005566 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005566">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A company advancing its controllable self-replicating RNA technology to develop therapies for a broad spectrum of diseases, including rare diseases, aging-related disorders, and cancer.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://elixirgentx.com</obo:IAO_0000119>
        <rdfs:label>Elixirgen Therapeutics, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005567 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005567">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A company offers pharmaceutical and specialized products to healthcare providers located in United States.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.bloomberg.com/profile/company/49277Z:US</obo:IAO_0000119>
        <rdfs:label>Emergent BioDefense Operations Lansing LLC</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005568 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005568">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A company located in Gaithersburg, Maryland.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://taggs.hhs.gov/Detail/RecipDetail?arg_EntityId=%2FLjAxy73AkKHW18%2FTlCD%2Fw%3D%3D</obo:IAO_0000119>
        <rdfs:label>Emergent Product Development Gaithersburg, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005569 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005569">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000115>A company dedicated to the production of a vaccine protective against malaria caused by the pathogen Plasmodium falciparum.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://sanaria.com</obo:IAO_0000119>
        <rdfs:label>Sanaria Inc., Rockville, MD</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005570 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005570">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.dnb.com/business-directory/company-profiles.seqirus_(australia)_pty_ltd.a3a1cc9f0ea41e8031a3b20bec6d9097.html</obo:IAO_0000119>
        <rdfs:label>Seqirus Pty. Ltd</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005571 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005571">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://find-and-update.company-information.service.gov.uk/company/03970089</obo:IAO_0000119>
        <rdfs:label>Seqirus Vaccines Limited</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0005572 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0005572">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000119>https://www.syneoshealth.com</obo:IAO_0000119>
        <rdfs:label>Syneos Health</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010377 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010377">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>Organon Teknika Corp., LLC</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010379 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010379">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>Merck Sharp &amp; Dohme LLC</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010380 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010380">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>Emergent Product Development Gaithersburg Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010381 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010381">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>Valneva Austria GmbH</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010382 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010382">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>Bavarian Nordic</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010383 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010383">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>ModernaTX, Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010384 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010384">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>Pfizer Ireland Pharmaceuticals</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010385 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010385">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>VBI Vaccines (Delaware) Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010386 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010386">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>Moderna Tx Inc.</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010387 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010387">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>MassBiologics</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010388 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010388">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>MSP Vaccine Company</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010392 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010392">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0000299"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>BioNTech Manufacturing GmbH</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010397 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010397">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2013-2014</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010398 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010398">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2014-2015</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010399 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010399">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2012-2013</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010400 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010400">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2011-2012</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010401 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010401">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010402 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010402">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010403 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010403">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010404 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010404">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2021-2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010405 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010405">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010406 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010406">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010407 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010407">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2010-2011</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010408 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010408">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010409 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010409">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2022-2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010410 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010410">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010411 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010411">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010412 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010412">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010413 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010413">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010414 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010414">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0010395"/>
        <obo:IAO_0000117>Ellen Zhang</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Xingxian Li</obo:IAO_0000117>
        <rdfs:label>flu season 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010458 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010458">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Comirnaty 2023-2024</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0010459 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0010459">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Spikevax 2023-2024</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015078 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015078">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 1</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015079 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015079">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 10</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015082 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015082">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 20</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015083 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015083">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 50</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015341 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015341">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Vaqta</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015342 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015342">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Epaxal</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015343 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015343">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Havpur</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015344 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015344">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Havrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015345 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015345">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Vivaxim</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015346 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015346">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Hepatyrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015347 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015347">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>ViATIM</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015348 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015348">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Hav Sorbat Ssw</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015349 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015349">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 2</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015350 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015350">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 3</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015351 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015351">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 5</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015352 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015352">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 25</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015353 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015353">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 40</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015354 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015354">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 80</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015355 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015355">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 100</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015356 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015356">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 250</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015357 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015357">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>AC Vax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015358 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015358">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Acel Imune</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015359 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015359">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Acel P Lederle</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015360 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015360">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Acel-P</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015361 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015361">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Act-HIB DTP</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015362 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015362">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>ActHIB</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015363 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015363">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>ACWY Vax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015364 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015364">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Adacel</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015365 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015365">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Adt Booster</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015366 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015366">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">Adt Vaccine</obo:IAO_0000118>
        <rdfs:label>Adt</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015367 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015367">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Ambirix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015368 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015368">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Anrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015369 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015369">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Arilvax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015370 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015370">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Attenuvax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015371 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015371">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Begrivac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015372 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015372">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Bexsero</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015373 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015373">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Bimmugen</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015374 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015374">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Biothrax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015375 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015375">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Boostrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015376 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015376">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Cervarix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015377 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015377">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Cervarix Grk</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015378 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015378">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Clostet</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015379 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015379">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Covaxis</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015380 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015380">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Di Te Tuss Asid</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015381 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015381">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Di Tetasorbat</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015382 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015382">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Diftavax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015383 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015383">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Dipht Toxoid Asid</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015384 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015384">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Diphtherie-Adsorbat-Impfstoff Behring</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015385 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015385">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Dpt Merieux</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015386 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015386">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Dpt Vaccinol</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015387 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015387">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Dt Impfstoff</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015388 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015388">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Dt Rix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015389 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015389">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Dt Vaccinol</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015390 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015390">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Dt Wellcovax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015391 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015391">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Dtp Rix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015392 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015392">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Engerix-B</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015393 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015393">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Enzira</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015394 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015394">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Ervevax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015395 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015395">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Eurim Pharm</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015396 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015396">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fendrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015397 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015397">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fsme Immun</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015398 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015398">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Gardasil</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015399 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015399">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Gemvites</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015400 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015400">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Gen Vax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015401 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015401">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>H B Vax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015402 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015402">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>H-B-Vax II</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015403 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015403">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>HBvaxPRO</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015404 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015404">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Hepasorbat</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015405 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015405">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Heptavax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015406 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015406">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Hevac B</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015407 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015407">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>HEXYON</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015408 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015408">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Hib Dpt Merieux</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015409 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015409">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Hibdpt Vaccinol</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015410 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015410">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Hibdt</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015411 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015411">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Hiberix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015412 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015412">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>HibTITER</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015413 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015413">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Imojev</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015414 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015414">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Imovax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015415 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015415">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Imuvac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015416 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015416">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Infanrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015417 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015417">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Infanrix Hexa</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015418 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015418">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Infanrix-Hib</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015419 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015419">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Invivac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015420 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015420">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Ipol</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015421 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015421">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Ixiaro</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015422 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015422">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Japanese encephalitis GCVC</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015423 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015423">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Je-Vax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015424 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015424">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Jespect</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015425 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015425">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Lt Grk</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015426 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015426">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>M-M-R II</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015427 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015427">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>M-M-RVAXPRO</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015428 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015428">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Mastaflu</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015429 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015429">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Menactra</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015430 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015430">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Mencevax Acwy</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015431 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015431">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Mengivac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015432 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015432">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Mengivac A + C</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015433 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015433">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Meningitec</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015434 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015434">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Menitorix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015435 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015435">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Menjugate</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015436 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015436">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Menquadfi</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015437 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015437">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Menveo</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015438 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015438">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Mmr Priorix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015439 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015439">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Moniarix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015440 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015440">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Multitest Cmi</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015441 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015441">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Mumpsvax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015442 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015442">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Neisvac C</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015443 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015443">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Nimenrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015444 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015444">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pa Vaccinol</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015445 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015445">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pac Merieux</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015446 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015446">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pediacel</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015447 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015447">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>PedvaxHIB</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015448 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015448">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pertuvac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015449 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015449">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pneumopur</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015450 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015450">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pneumorix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015451 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015451">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pneumovax 23</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015452 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015452">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pneumovax II</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015453 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015453">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pnu-Imune</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015454 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015454">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Polio Sabin-Rit Multi</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015455 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015455">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Polio Sabin-S</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015456 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015456">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Poliovaccine Ssi</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015457 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015457">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Prevnar</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015458 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015458">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Priorix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015459 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015459">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Priorix-Tetra</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015460 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015460">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Procomvax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015461 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015461">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>ProQuad</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015462 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015462">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Quadracel</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015463 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015463">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Quatro Virelon No</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015464 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015464">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>RabAvert</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015465 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015465">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Rabipur</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015466 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015466">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Rabivac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015467 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015467">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Recombivax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015468 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015468">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Repevax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015469 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015469">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Revaxis</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015470 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015470">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Rotarix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015477 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015477">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>RUDIVAX</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015479 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015479">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Silgard</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015480 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015480">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Stamaril</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015481 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015481">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Synflorix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0015482 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0015482">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>T Immun</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018810 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018810">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>T Medevax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018811 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018811">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>T Polio Adsorbed</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018812 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018812">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>T Vaccinol</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018813 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018813">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>T Wellcovax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018814 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018814">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>T-Immun Immuno</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018815 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018815">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tab Impfstoff</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018816 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018816">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Td Impfstoff</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018817 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018817">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Td-Impfstoff Merieux</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018818 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018818">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Td-Pur</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018819 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018819">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tet Aktiv</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018820 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018820">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tetabulin</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018821 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018821">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tetamun</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018822 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018822">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tetanol</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018823 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018823">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tetanus-Impfstoff Merieux</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018824 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018824">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tetasorbat</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018825 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018825">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tetatoxoid</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018826 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018826">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tetravac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018827 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018827">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>TicoVac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018828 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018828">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tollwut-Impfstoff</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018829 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018829">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tri-Immunol Im</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018830 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018830">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Triaxis</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018831 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018831">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tripacel</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018832 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018832">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Trumenba</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018833 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018833">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tussoglobin</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018834 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018834">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Twinrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018835 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018835">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Twinrix Adult</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018836 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018836">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Twinrix Paediatric</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018837 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018837">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Typherix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018838 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018838">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Typhim VI</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018839 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018839">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>VACCIN GENHEVAC B</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018840 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018840">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>VACCIN RABIQUE INACTIVE MERIEUX</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018841 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018841">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Verorab</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018842 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018842">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Vivotif Berna</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018930 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018930">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>ACAM2000</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018931 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018931">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>ACEL-IMUNE</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018932 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018932">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria 2010-2011 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018933 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018933">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria 2011-2012 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018934 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018934">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018935 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018935">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018936 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018936">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018937 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018937">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018938 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018938">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018939 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018939">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018940 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018940">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018941 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018941">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria Quadrivalent 2016-2017 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018942 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018942">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria Quadrivalent 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018943 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018943">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria Quadrivalent 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018944 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018944">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria Quadrivalent 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018945 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018945">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria Quadrivalent 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018946 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018946">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria Quadrivalent 2021-2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018947 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018947">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria Quadrivalent 2022-2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018948 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018948">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Agriflu 2010-2011 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018949 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018949">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Agriflu 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018950 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018950">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Biavax II</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018951 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018951">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Certiva</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018952 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018952">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Comirnaty</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018953 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018953">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>COMVAX</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018954 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018954">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Daptacel</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018955 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018955">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Decavac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018956 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018956">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Dryvax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018957 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018957">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>FLUAD 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018958 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018958">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluad 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018959 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018959">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluad 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018960 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018960">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluad 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018961 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018961">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluad 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018962 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018962">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluad 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018963 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018963">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluad Quadrivalent 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018964 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018964">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluad Quadrivalent 2021-2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018965 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018965">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluad Quadrivalent 2022-2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018966 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018966">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix 2010-2011 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018967 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018967">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix 2011-2012 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018968 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018968">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018969 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018969">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018970 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018970">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018971 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018971">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix Quad 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018972 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018972">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix Quadrivalent 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018973 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018973">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix Quadrivalent 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018974 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018974">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix Quadrivalent 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018975 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018975">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix Quadrivalent 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018976 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018976">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix Quadrivalent 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018977 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018977">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix Quadrivalent 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018978 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018978">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix Quadrivalent 2021-2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018979 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018979">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix Quadrivalent 2022-2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018980 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018980">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018981 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018981">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018982 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018982">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018983 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018983">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018984 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018984">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018985 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018985">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018986 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018986">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok Quadrivalent 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018987 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018987">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok Quadrivalent 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018988 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018988">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok Quadrivalent 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018989 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018989">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok Quadrivalent 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018990 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018990">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok Quadrivalent 2021-2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018991 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018991">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flublok Quadrivalent 2022-2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018992 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018992">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018993 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018993">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018994 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018994">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018995 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018995">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018996 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018996">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax Quadrivalent 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018997 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018997">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax Quadrivalent 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018998 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018998">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax Quadrivalent 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0018999 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0018999">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax Quadrivalent 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019000 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019000">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax Quadrivalent 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019001 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019001">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax Quadrivalent 2021-2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019002 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019002">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flucelvax Quadrivalent 2022-2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019003 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019003">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>FluLaval 2010-2011 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019004 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019004">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval 2011-2012 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019005 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019005">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019006 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019006">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019007 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019007">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019008 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019008">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval Quad 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019009 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019009">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval Quad 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019010 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019010">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>FluLaval Quadrivalent 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019011 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019011">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval Quadrivalent 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019012 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019012">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval Quadrivalent 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019013 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019013">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval Quadrivalent 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019014 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019014">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval Quadrivalent 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019015 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019015">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval Quadrivalent 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019016 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019016">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval Quadrivalent 2021-2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019017 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019017">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flulaval Quadrivalent 2022-2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019018 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019018">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>FluMist 2010-2011 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019019 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019019">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flumist 2011-2012 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019020 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019020">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flumist 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019021 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019021">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flumist 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019022 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019022">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flumist 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019023 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019023">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flumist Quadrivalent 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019024 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019024">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flumist Quadrivalent 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019025 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019025">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flumist Quadrivalent 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019026 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019026">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>FluMist Quadrivalent 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019027 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019027">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flumist Quadrivalent 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019028 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019028">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>FluMist Quadrivalent 2021-2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019029 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019029">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>FluMist Quadrivalent 2022-2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019030 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019030">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluvirin 2010-2011 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019031 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019031">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluvirin 2011-2012 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019032 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019032">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluvirin 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019033 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019033">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluvirin 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019034 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019034">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluvirin 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019035 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019035">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluvirin 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019036 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019036">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluvirin 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019037 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019037">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluvirin 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019038 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019038">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2010-2011 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019039 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019039">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2011-2012 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019040 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019040">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019041 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019041">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019042 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019042">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019043 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019043">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019044 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019044">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019045 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019045">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019046 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019046">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019047 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019047">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019048 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019048">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone High-Dose 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019049 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019049">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone High-Dose 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019050 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019050">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone High-Dose 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019051 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019051">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Intradermal 2012-2013 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019052 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019052">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Intradermal 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019053 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019053">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Intradermal 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019054 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019054">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2013-2014 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019055 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019055">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2014-2015 Formula</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019056 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019056">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2015-2016</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019057 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019057">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2016 Southern Hemisphere</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019058 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019058">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2016-2017</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019059 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019059">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2017-2018</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019060 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019060">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2018-2019</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019061 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019061">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2019-2020</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019062 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019062">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2020 Southern Hemisphere</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019063 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019063">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2020-2021</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019064 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019064">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2021 Southern Hemisphere</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019065 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019065">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2021-2022</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019066 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019066">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2022 Southern Hemisphere</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019067 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019067">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2022-2023</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019068 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019068">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluzone Quadrivalent 2023 Southern Hemisphere</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019069 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019069">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Gardasil 9</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019070 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019070">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>HB-VAX</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019071 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019071">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Heplisav-B</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019072 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019072">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Kinrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019073 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019073">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Liquid PedvaxHIB</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019074 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019074">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>MenHibrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019075 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019075">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Meningovax-AC</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019076 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019076">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Menomune A/C/Y/W-135</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019077 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019077">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Meruvax II</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019078 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019078">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>OmniHIB</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019079 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019079">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pediarix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019080 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019080">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pentacel</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019081 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019081">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Prehevbrio</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019082 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019082">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Prevnar 13</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019083 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019083">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Prohibit</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019084 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019084">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>RotaTeq</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019085 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019085">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Shingrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019086 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019086">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Spikevax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019087 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019087">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tdvax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019088 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019088">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>TE Anatoxal Berna</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019089 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019089">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tenivac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019090 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019090">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Tripedia</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019091 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019091">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Varivax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019092 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019092">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Vaxchora</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019093 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019093">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Vaxelis</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019094 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019094">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Vivotif</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019095 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019095">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>YF-Vax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019096 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019096">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Zostavax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0019418 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0019418">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Liquid Pedvax HIB</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020356 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0020356">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Typhim V</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020357 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0020357">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Typhoral L</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020650 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0020650">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Afluria</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0020653 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0020653">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Agrippal</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021049 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021049">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Alpha RIX Tetra</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021050 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021050">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Bcg Medac</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021051 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021051">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Begripal</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021052 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021052">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluad</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021053 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021053">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluarix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021054 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021054">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluenz</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021055 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021055">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Flumist</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021056 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021056">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>FluMist Quadrivalent</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021057 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021057">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Fluvax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021058 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021058">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Grippe-Impfstoff Csl</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021059 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021059">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Grippe-Impfstoff Stada</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021060 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021060">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Grippeimpfstoff Ratiopharm</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021061 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021061">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>ImmuCyst</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021062 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021062">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>IMMUGRIP</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021063 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021063">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Inflexal</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021064 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021064">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Influsplit</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021065 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021065">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>INFLUVAC</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021066 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021066">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Intanza</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021067 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021067">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>InterVax</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021068 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021068">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Metavirulent</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021069 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021069">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>OncoTICE</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021070 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021070">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Oncotice Bcg</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021071 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021071">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pacis</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021072 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021072">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Pandemrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021073 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021073">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Preflucel</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021074 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021074">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Varilrix</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021075 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021075">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>VAXIGRIP</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021076 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021076">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Vaxigrip Junior</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021077 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021077">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Viroflu</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021078 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021078">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015077"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Xanaflu</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- http://purl.obolibrary.org/obo/VO_0021079 -->

    <owl:NamedIndividual rdf:about="http://purl.obolibrary.org/obo/VO_0021079">
        <rdf:type rdf:resource="http://purl.obolibrary.org/obo/VO_0015076"/>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <rdfs:label>Box of 6</rdfs:label>
    </owl:NamedIndividual>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotations
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <rdf:Description rdf:about="http://bioportal.bioontology.org/ontologies/versionSubject">
        <owl:versionInfo>2025-05-24</owl:versionInfo>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <obo:IAO_0000111 xml:lang="en">has part</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">my body has part my brain (continuant parthood, two material entities)</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this year has part this day (occurrent parthood)</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a core relation that holds between a whole and its part</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)

A continuant cannot have an occurrent as part: use &apos;participates in&apos;. An occurrent cannot have a continuant as part: use &apos;has participant&apos;. An immaterial entity cannot have a material entity as part: use &apos;location of&apos;. An independent continuant cannot have a specifically dependent continuant as part: use &apos;bearer of&apos;. A specifically dependent continuant cannot have an independent continuant as part: use &apos;inheres in&apos;.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">has_part</obo:IAO_0000118>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000054">
        <obo:IAO_0000111 xml:lang="en">realized in</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">this disease is realized in this disease course</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this fragility is realized in this shattering</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this investigator role is realized in this investigation</obo:IAO_0000112>
        <obo:IAO_0000118 xml:lang="en">is realized by</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">realized_in</obo:IAO_0000118>
        <obo:IAO_0000600 xml:lang="en">[copied from inverse property &apos;realizes&apos;] to say that b realizes c at t is to assert that there is some material entity d &amp; b is a process which has participant d at t &amp; c is a disposition or role of which d is bearer_of at t&amp; the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])</obo:IAO_0000600>
        <rdfs:comment>Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process</rdfs:comment>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">realized in</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000055">
        <obo:IAO_0000111 xml:lang="en">realizes</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">this disease course realizes this disease</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this investigation realizes this investigator role</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this shattering realizes this fragility</obo:IAO_0000112>
        <obo:IAO_0000600 xml:lang="en">to say that b realizes c at t is to assert that there is some material entity d &amp; b is a process which has participant d at t &amp; c is a disposition or role of which d is bearer_of at t&amp; the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])</obo:IAO_0000600>
        <rdfs:comment>Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process</rdfs:comment>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">realizes</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062">
        <obo:IAO_0000111 xml:lang="en">preceded by</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) &lt;= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C.    The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">is preceded by</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">preceded_by</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <terms:source>http://www.obofoundry.org/ro/#OBO_REL:preceded_by</terms:source>
        <rdfs:label xml:lang="en">preceded by</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066">
        <obo:IAO_0000111 xml:lang="en">occurs in</obo:IAO_0000111>
        <obo:IAO_0000115 xml:lang="en">b occurs_in c =def b is a process and c is a material entity or immaterial entity&amp; there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.&amp; forall(t) if b exists_at t then c exists_at t &amp; there exist spatial regions s and s’ where &amp; b spatially_projects_onto s at t&amp; c is occupies_spatial_region s’ at t&amp; s is a proper_continuant_part_of s’ at t</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">occurs_in</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">unfolds in</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">unfolds_in</obo:IAO_0000118>
        <rdfs:comment>Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant</rdfs:comment>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/bfo.owl"/>
        <rdfs:label xml:lang="en">occurs in</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000136">
        <obo:IAO_0000112 xml:lang="en">This document is about information artifacts and their representations</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">A (currently) primitive relation that relates an information artifact to an entity.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of &quot;mentions&quot; relation. Weaken the is_about relationship to be primitive. 

We will try to build it back up by elaborating the various subproperties that are more precisely defined.

Some currently missing phenomena that should be considered &quot;about&quot; are predications - &quot;The only person who knows the answer is sitting beside me&quot; , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">person:Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Smith, Ceusters, Ruttenberg, 2000 years of philosophy</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">is about</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000142">
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">An information artifact IA mentions an entity E exactly when it has a component/part that denotes E</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">7/6/2009 Alan Ruttenberg. P4 RC1 munges our GCI so remove it for now: mentions some entity equivalentTo has_part some (&apos;generically denotes&apos; some entity)</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">7/6/2009 Alan Ruttenberg: Add this relation following conversation with Jonathan Rees that N&amp;S GCI for is_about was too strong. Really it was simply sufficient. To effect this change we introduce this relation, which is subproperty of is_about, and have previous GCI use this relation &quot;mentions&quot; in it&apos;s (logical) definition</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Jonathan Rees</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Person: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/iao.owl"/>
        <rdfs:label xml:lang="en">mentions</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000293">
        <obo:IAO_0000111>has_specified_input</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">see is_input_of example_of_usage</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">The inverse property of is_specified_input_of</obo:IAO_0000115>
        <obo:IAO_0000116>8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how &apos;has participant&apos; works.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Larry Hunter</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Melanie Coutot</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">has_specified_input</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000295">
        <obo:IAO_0000111>is_specified_input_of</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">is_specified_input_of</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000299">
        <obo:IAO_0000111>has_specified_output</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">The inverse property of is_specified_output_of</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Larry Hunter</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">has_specified_output</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000312">
        <obo:IAO_0000111>is_specified_output_of</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
        <obo:IAO_0000115 xml:lang="en">A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000117>PERSON:Bjoern Peters</obo:IAO_0000117>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label xml:lang="en">is_specified_output_of</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000417">
        <obo:IAO_0000111>achieves_planned_objective</obo:IAO_0000111>
        <obo:IAO_0000112>A cell sorting process achieves the objective specification &apos;material separation objective&apos;</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.</obo:IAO_0000115>
        <obo:IAO_0000117>BP, AR, PPPB branch</obo:IAO_0000117>
        <obo:IAO_0000119>PPPB branch derived</obo:IAO_0000119>
        <obo:IAO_0000232>modified according to email thread from 1/23/09 in accordince with DT and PPPB branch</obo:IAO_0000232>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>achieves_planned_objective</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000643">
        <obo:IAO_0000111>has grain</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. Definition take from the definition of granular parthood in the cited paper. Needs work to put into standard form</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">PERSON: Alan Ruttenberg</obo:IAO_0000117>
        <obo:IAO_0000119>PAPER: Granularity, scale and collectivity: When size does and does not matter, Alan Rector, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>has grain</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0001938">
        <obo:IAO_0000111>has value specification</obo:IAO_0000111>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A relation between an information content entity and a value specification that specifies its value.</obo:IAO_0000115>
        <obo:IAO_0000117>PERSON: James A. Overton</obo:IAO_0000117>
        <obo:IAO_0000119>OBI</obo:IAO_0000119>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/obi.owl"/>
        <rdfs:label>has value specification</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <obo:IAO_0000111 xml:lang="en">inheres in</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">this fragility is a characteristic of this vase</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this red color is a characteristic of this apple</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">inheres_in</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:comment>Note that this relation was previously called &quot;inheres in&quot;, but was changed to be called &quot;characteristic of&quot; because BFO2 uses &quot;inheres in&quot; in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.</rdfs:comment>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000056">
        <obo:IAO_0000111 xml:lang="en">participates in</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">this blood clot participates in this blood coagulation</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this input material (or this output material) participates in this process</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this investigator participates in this investigation</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between a continuant and a process, in which the continuant is somehow involved in the process</obo:IAO_0000115>
        <obo:IAO_0000118 xml:lang="en">participates_in</obo:IAO_0000118>
        <rdfs:label xml:lang="en">participates in</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000057">
        <obo:IAO_0000111 xml:lang="en">has participant</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">this blood coagulation has participant this blood clot</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this investigation has participant this investigator</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this process has participant this input material (or this output material)</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between a process and a continuant, in which the continuant is somehow involved in the process</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">has_participant</obo:IAO_0000118>
        <terms:source>http://www.obofoundry.org/ro/#OBO_REL:has_participant</terms:source>
        <rdfs:label xml:lang="en">has participant</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000085">
        <obo:IAO_0000112 xml:lang="en">this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">has_function</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">has function</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000086">
        <obo:IAO_0000112 xml:lang="en">this apple has quality this red color</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">has_quality</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">has quality</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <obo:IAO_0000112 xml:lang="en">this person has role this investigator role (more colloquially: this person has this role of investigator)</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">has_role</obo:IAO_0000118>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000091">
        <obo:IAO_0000115 xml:lang="en">a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence</obo:IAO_0000115>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">has disposition</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001000">
        <obo:IAO_0000112 xml:lang="en">this cell derives from this parent cell (cell division)</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this nucleus derives from this parent nucleus (nuclear division)</obo:IAO_0000112>
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115 xml:lang="en">a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">This is a very general relation. More specific relations are preferred when applicable, such as &apos;directly develops from&apos;.</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">derives_from</obo:IAO_0000118>
        <rdfs:label xml:lang="en">derives from</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001025">
        <obo:IAO_0000111 xml:lang="en">located in</obo:IAO_0000111>
        <obo:IAO_0000112 xml:lang="en">my brain is located in my head</obo:IAO_0000112>
        <obo:IAO_0000112 xml:lang="en">this rat is located in this cage</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">a relation between two independent continuants, the target and the location, in which the target is entirely within the location</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1.    Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/</obo:IAO_0000116>
        <obo:IAO_0000118 xml:lang="en">located_in</obo:IAO_0000118>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <terms:source>http://www.obofoundry.org/ro/#OBO_REL:located_in</terms:source>
        <rdfs:label xml:lang="en">located in</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162">
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115>x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0001-9227-417X"/>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/17921072"/>
        <obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20973947"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/ro/subsets#ro-eco"/>
        <rdfs:comment>Connects a biological entity to its taxon of origin.</rdfs:comment>
        <rdfs:label>in taxon</rdfs:label>
        <rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002180">
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115>w &apos;has component&apos; p if w &apos;has part&apos; p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.</obo:IAO_0000115>
        <obo:IAO_0000116>The definition of &apos;has component&apos; is still under discussion. The challenge is in providing a definition that does not imply transitivity.</obo:IAO_0000116>
        <obo:IAO_0000232 xml:lang="en">For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like &apos;has part exactly 5 digit, you would instead use has_component exactly 5 digit.</obo:IAO_0000232>
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        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/ro/subsets#ro-eco"/>
        <rdfs:label xml:lang="en">has component</rdfs:label>
        <rdfs:seeAlso rdf:resource="http://ontologydesignpatterns.org/wiki/Submissions:Componency"/>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002292">
        <obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
        <obo:IAO_0000115>y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process.</obo:IAO_0000115>
        <obo:IAO_0000117 rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <rdfs:label xml:lang="en">expresses</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002351">
        <obo:IAO_0000115>has member is a mereological relation between a collection and an item.</obo:IAO_0000115>
        <obo:IAO_0000119>SIO</obo:IAO_0000119>
        <obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
        <rdfs:label xml:lang="en">has member</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0004019">
        <obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ro.owl"/>
        <oboInOwl:created_by rdf:resource="https://orcid.org/0000-0002-6601-2165"/>
        <oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-11-05T03:26:47Z</oboInOwl:creation_date>
        <rdfs:label>disease has basis in</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000531">
        <obo:IAO_0000115>An object property that specifies a relation between a vaccine and a vaccine allergen</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has vaccine allergen</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0000547">
        <obo:IAO_0000115>An object property that specifies a relation between a vaccine and a vaccinate route</obo:IAO_0000115>
        <rdfs:label>vaccinated in route</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001011">
        <obo:IAO_0000115>A shortcut relation that is equivalent to:
&apos;processed material&apos; and (is_specified_output_of some &apos;vaccine preparation&apos;) and (&apos;has function&apos; some (&apos;vaccine function&apos; and (&apos;is realized by&apos; only (&apos;vaccine immunization&apos; and (realizes some (&apos;vaccine host role&apos; and (role_of some &apos;organism&apos; and has_disposition some disease)))))))).
The domain of this relation is a vaccine.
The range of this relation is a disease.</obo:IAO_0000115>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>immunization against disease</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine immunization against disease</obo:IAO_0000118>
        <rdfs:label>immunizes against disease</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001039">
        <obo:IAO_0000115>An object property that represents an organism has a mutation of a specific gene from the organism genome.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has gene mutation</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0001243">
        <obo:IAO_0000115>A shortcut relation that is equivalent to:
&apos;processed material&apos; and (is_specified_output_of some &apos;vaccine preparation&apos;) and (&apos;has function&apos; some (&apos;vaccine function&apos; and (&apos;is realized by&apos; only (&apos;vaccine immunization&apos; and (realizes some (&apos;vaccine recipient role&apos; and (role_of some &apos;organism&apos;)))))))).
The domain of this relation is a vaccine.
The range of this relation is a organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Anna Maria Masci</obo:IAO_0000117>
        <obo:IAO_0000117>Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000117>Barry Smith</obo:IAO_0000117>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>immunization for host</obo:IAO_0000118>
        <obo:IAO_0000118>immunization for recipient</obo:IAO_0000118>
        <obo:IAO_0000118>immunizes host</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine immunization for host</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine immunization for recipient</obo:IAO_0000118>
        <rdfs:label>immunizes recipient</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0003355">
        <obo:IAO_0000115>A shortcut relation that is equivalent to:
processed material and (is_specified_output_of some vaccine preparation) and (has function some (vaccine function and (is realized by only (vaccine immunization and (realizes some (&apos;immunization target role&apos; and (role_of some &apos;pathogen&apos;))))))))

The domain of this relation is a vaccine.
The range of this relation is a pathogen (a bacterium, a virus, a fungus, and a parasite)
Ranges: organism and &apos;has role&apos; some &apos;pathogen role&apos;</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>immunization against pathogen</obo:IAO_0000118>
        <obo:IAO_0000118>immunizes against microbe</obo:IAO_0000118>
        <obo:IAO_0000118>vaccine immunization against pathogen</obo:IAO_0000118>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/675</obo:IAO_0000233>
        <rdfs:label>immunizes against pathogen</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0003390">
        <obo:IAO_0000115>A shortcut relation that is equivalent to:
(&apos;vaccine&apos; and &apos;has function&apos; some (&apos;vaccine function&apos; and (&apos;is realized by&apos; some (&apos;vaccine immunization&apos; and &apos;has participant&apos; some (&apos;organism&apos; and &apos;has role&apos; some &apos;laboratory animal model role&apos;))))).
The domain of this relation is a vaccine.
The range of this relation is a organism.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>test in lab animal model</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0005312">
        <obo:IAO_0000115>An object property that represents a relation between a material entity (such as vaccine or vaccine adjuvant) and an immune profile where the material entity can induce the immune profile in a host.</obo:IAO_0000115>
        <obo:IAO_0000117>Amogh Madireddi</obo:IAO_0000117>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>induces immune profile</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0005377">
        <obo:IAO_0000112>A vaccine adjuvant T-vant has molecular receptor of TLR4. Reference: https://vac.niaid.nih.gov/view?id=61.</obo:IAO_0000112>
        <obo:IAO_0000115>An object property that represents a relation between a material entity and a molecular entitiy that serves as the molecular receptor to the material entity.</obo:IAO_0000115>
        <obo:IAO_0000117>Oliver He</obo:IAO_0000117>
        <rdfs:label>has molecular receptor</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0005561">
        <obo:IAO_0000115>A relation between a vaccine and a parasite where the vaccine immunizes against some parasite such that the parasite is blocked transmitting to additional hosts or vectors.</obo:IAO_0000115>
        <obo:IAO_0000233>https://github.com/vaccineontology/VO/issues/675</obo:IAO_0000233>
        <rdfs:label>blocks transmission of pathogen via vaccine</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0005562">
        <obo:IAO_0000115>A relation between a vaccine X and organism Y where the vaccine X generates an immune response in a vaccinated organism and the immune product (e.g., antibody) can be transferred to the organism Y</obo:IAO_0000115>
        <rdfs:label>vaccine immunity response transferrable to organism</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/VO_0015007">
        <obo:IAO_0000117>Jie Zheng</obo:IAO_0000117>
        <obo:IAO_0000233>drug form</obo:IAO_0000233>
        <rdfs:label>has drug dose form</rdfs:label>
    </rdf:Description>
    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/vo.owl">
        <protege:defaultLanguage>en</protege:defaultLanguage>
        <dc:contributor>Chris mungall</dc:contributor>
        <dc:contributor>Erica Marcos</dc:contributor>
        <dc:contributor>Ningxian Fan</dc:contributor>
        <dc:contributor>Paul Fabry</dc:contributor>
        <dc:contributor>Randi Vita</dc:contributor>
        <dc:contributor>Ryan R. Brinkman</dc:contributor>
        <dc:contributor>Shunzhou Deng</dc:contributor>
        <dc:creator>Alan Ruttenburg</dc:creator>
        <dc:creator>Alexander D. Diehl</dc:creator>
        <dc:creator>Amogh Madireddi</dc:creator>
        <dc:creator>Anna Maria Masci</dc:creator>
        <dc:creator>Anthony Huffman</dc:creator>
        <dc:creator>Barry Smith</dc:creator>
        <dc:creator>Bjoern Peters</dc:creator>
        <dc:creator>Edison Ong</dc:creator>
        <dc:creator>Ellen Zhang</dc:creator>
        <dc:creator>Hong Yu</dc:creator>
        <dc:creator>Jason Hu</dc:creator>
        <dc:creator>Jie Zheng</dc:creator>
        <dc:creator>Kallan Roan</dc:creator>
        <dc:creator>Khadeejah Khan</dc:creator>
        <dc:creator>Lindsay Cowell</dc:creator>
        <dc:creator>Melanie Courtot</dc:creator>
        <dc:creator>Ningxian Fan</dc:creator>
        <dc:creator>Omar Tibi</dc:creator>
        <dc:creator>Philip Huang</dc:creator>
        <dc:creator>Randi Vita</dc:creator>
        <dc:creator>Rebecca Racz</dc:creator>
        <dc:creator>Richard H. Scheuermann</dc:creator>
        <dc:creator>Rohit Goru</dc:creator>
        <dc:creator>Ronak Sutariya</dc:creator>
        <dc:creator>Samantha G. Sayers (SGS)</dc:creator>
        <dc:creator>Taiyu Lin</dc:creator>
        <dc:creator>Thomas Todd</dc:creator>
        <dc:creator>Xingxian Li</dc:creator>
        <dc:creator>Yongqun &quot;Oliver&quot; He (YH)</dc:creator>
        <dc:creator>Yu Lin (YL)</dc:creator>
        <dc:creator>Yuanyi (Penny) Pan</dc:creator>
        <dc:creator>Yuping Zheng</dc:creator>
        <dc:creator>Zuoshuang &quot;Allen&quot; Xiang</dc:creator>
        <dc:description xml:lang="en">The Vaccine Ontology (VO) is a community-based biomedical ontology in the domain of vaccine and vaccination. VO aims to standardize vaccine types and annotations, integrate various vaccine data, and support computer-assisted reasoning. The VO supports basic vaccine R&amp;D and clinical vaccine usage. VO is being developed as a community-based ontology with support and collaborations from the vaccine and bio-ontology communities.</dc:description>
        <dc:format xml:lang="en">OWL-DL</dc:format>
        <dc:subject xml:lang="en">An ontology in the domain of vaccine and vaccination</dc:subject>
        <dc:title xml:lang="en">Vaccine Ontology</dc:title>
        <terms:license rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
        <owl:versionInfo>2025-05-24</owl:versionInfo>
    </rdf:Description>
    


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                        <rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
                        <swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0000085"/>
                        <swrl:argument1 rdf:resource="urn:swrl:var#e"/>
                        <swrl:argument2 rdf:resource="urn:swrl:var#d"/>
                    </rdf:Description>
                </rdf:first>
                <rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
            </rdf:Description>
        </swrl:head>
    </rdf:Description>
</rdf:RDF>



<!-- Generated by the OWL API (version 4.5.18) https://github.com/owlcs/owlapi -->

